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1 at the Miller&Payne 4/5 pathological response, indicating 90-100% tumor-cell loss, is more likely to
2 initiation factor 4A [eIF4A], eIF4B, and Ded1), indicating a common mechanism of translational repres
3 kinetochore MAD2 was dependent on APC/C(CDC20), indicating a feedback control of APC/C to SAC during
5 could be observed during cisplatin treatment, indicating a cell line-specific and platin-dependent a
6 ut also additional modifications are detected, indicating a certain plasticity of the pathway in the
7 3K9me3 in mdx mice compared to wild-type mice, indicating a chromatin conformation less prone to tran
8 ost in some tumors, it is increased in others, indicating a conditional pro-survival function of casp
9 th or without deficiency in adaptive immunity, indicating a critical role for innate immunity in endo
10 s were eventually detected in large intestine, indicating a critical role of the plasmid in chlamydia
11 y replenishing extracellular glutamate levels, indicating a defect linked with decreased extracellula
12 ion to cope with exogenous oxidative stresses, indicating a direct link between both thiol systems.
13 silencing results in reduced ZIKV replication, indicating a direct role of Hippo pathway in regulatin
14 tral surround suppression in excitatory cells, indicating a dominant causal role for SOM(+) cells in
15 th rate when compared with their founder cell, indicating a dynamic nature in the capacity to survive
16 ing effector that can induce c-Myc expression, indicating a functional departure from the canonical M
18 tive site under comparable X-ray illumination, indicating a much more rigid protein architecture.
20 s once a pure carbon dioxide feed is restored, indicating a negligible long-term impact of nitrogen o
21 een VDAC1 and other receptor tyrosine kinases, indicating a novel role for this family of receptors i
23 the constant development of B cells in vitro, indicating a possible low frequency or exhaustion of t
24 ategy in women and lower strength individuals, indicating a possible role in knee joint injury and mo
25 ignatures similar to postmortem brain studies, indicating a potential common biological mechanism.
26 helial cell cluster almost exclusively in DFU, indicating a potential important role in wound healing
27 total HBV core antibody (anti-HBc) positivity, indicating a previous or ongoing HBV infection, among
29 osinophil migration, additively with 1-NM-PP1, indicating a role for matrix metalloproteases in TrkA
31 transcription factor PIF4 fails to accumulate, indicating a role of SPAs in regulating the phyB-PIF4
34 away from surfaces when vision is unavailable, indicating a short-range, mechanosensory collision-avo
35 red to the same stretch in the CF(3) analogue, indicating a significantly stronger HB interaction in
37 ently captured in pharmacovigilance databases, indicating a strong need for a more robust system of r
38 common than those from cardiovascular disease, indicating a transition in the predominant causes of d
39 matched against the full Arabidopsis proteome, indicating a unique evolution of plastid targeting.
40 glutamine and other nitrogen-rich amino acids, indicating active protein breakdown, at a rate ~10 tim
41 ation than those from the carbonate catchment, indicating adaptation to use H(2) as a reductant in ba
42 nd a high twitch/tetanus ratio (0.91 +/- 0.05), indicating adaptations for fast excitation-contractio
43 n of border coding in RSC, but not vice versa, indicating allocentric-to-egocentric transformation.
44 that inflammatory genes are highly translated, indicating alternative post-transcriptional regulation
45 was inversely correlated with PD-1 expression, indicating an exhausted status of SATB1-negative malig
47 ement provides manual feedback to the surgeon, indicating an impending breach if continued directiona
48 size decreased, polymer degradation increased, indicating an increase in aerosol acidity at smaller p
50 gnificant FMREs at cancer genes and processes, indicating an unexplored landscape of infrequent drive
51 d AID activity during the pre-malignant phase, indicating antigen-responsiveness and germinal center
52 ndogenous homologous transcript as a template, indicating ATXN3's role in PNKP-mediated error-free C-
54 ory pigment analysis displayed similar trends, indicating chlorophytes were the dominant microalgal g
55 HCFC-141b, HCFC-142b, CH(2)Cl(2), and HCFC-22, indicating co-location of the emissions of these compo
56 a flux period of h/e (h is Planck's constant), indicating coherent transport of single electrons thr
57 n of ZmPTPN inhibited plant drought tolerance, indicating conserved and positive roles of PTPN in pla
58 e commonness and rarity of individual species, indicating considerable turnover in community composit
59 oxygen sensor RELATED TO APETALA2 12 (RAP2.12), indicating convergence of oxygen signaling with epige
60 blocked by both alpha-bungarotoxin and apamin, indicating coupling of ACh-mediated effects to small-c
61 ining telomere dysfunction-induced foci (TIFs), indicating defects in DNA damage checkpoint signaling
62 h growth and DTG expression requires the PIFs, indicating direct action on PIF activity, rather than
63 r El Nino events of 1983, 1997/98 and 2015/16, indicating drought conditions with less river runoff,
64 nd phenotypic effects of prolonged treatments, indicating durable changes in cellular physiologic ide
65 lets, but not in type 2 diabetic (T2D) islets, indicating dysregulation of lipolysis in T2D islets.
66 ly increased the performance of the community, indicating ecosystem-wide multitrophic complementarity
68 d higher in dead fry than in live fingerlings, indicating either off-target effects or pleiotropic ef
70 ilms grown at 200 degrees C under 15 mTorr Ar, indicating excellent crystallinity and surface smoothn
71 and snRNP assembly in the absence of flwt-Smn, indicating exon 2B is not required for the essential f
72 lants containing F187 were completely fertile, indicating fertility restoration, and plants containin
74 onize the phenotypes induced by P. gingivalis, indicating functionally specialized roles for bacteria
75 rphology of fully differentiated neural cells, indicating fusion between the cancer and neural stem c
76 ans was also observed in the Deltagpi7 mutant, indicating GPI-anchored proteins are required for immu
78 mponent scores for refined grains and protein, indicating higher age-appropriate intakes (P < 0.05).
81 in the Kyrgyz Republic between 1997 and 2014, indicating increased intrauterine growth and populatio
83 compared to PBC patients and healthy controls, indicating increased Th17 differentiation in vivo.
86 role in the maintenance of the CSC phenotype, indicating it is a potential therapeutic target in HNS
88 nd reversed immunosuppression in mouse models, indicating its potential as an in vivo tool compound f
89 electivity to NTMT1/2 among a panel of 41 MTs, indicating its potential to achieve high selectivity w
90 hy and skeletal muscle weakness of human IOPD, indicating its utility for evaluation of novel therape
92 fluences that affect one stage of development, indicating limited pleiotropic consequences for most m
94 s were absent from the bone marrow and spleen, indicating local acquisition of the SiglecF(hi) signat
96 ere significantly lower in males than females, indicating males spent more time foraging south of the
98 ) m s(-1) (10-100 mm day(-1) to 1-10 m day(-1)), indicating meter sized crystals could have formed wi
99 RLT were preventable such as DR, DMO and RVO, indicating need to control systemic diseases such as d
101 RCIST1 and imPERCIST5 (P = 0.5), respectively, indicating no significant difference between analyzing
105 to the ratio of carbon isotopes ((13)C/(12)C), indicating positive correlations to dietary intake of
106 ent size fractions to classify viral clusters, indicating potential diverse interactions with their h
107 tus (T2DM) show cognitive and mood impairment, indicating potential for brain injury in regions that
109 ingly enriched at DARs during differentiation, indicating regulatory networks that likely drive GIN d
110 in undetectable using isolation-based methods, indicating selective culturability for some members of
112 ing the day were nearly double those at night, indicating sifnificant fermentation rates even during
113 bond-length alternation upon photoexcitation, indicating significant cumulenic character of the brid
114 s in improved late-life ejaculate performance, indicating simultaneous amelioration of both somatic a
115 rtionality after amputation in normal animals, indicating STRIPAK represses Wnt signaling for scaling
116 ion was achieved and rhabdoms remained narrow, indicating strong circadian control on the process.
118 lic' clonotypes found in multiple individuals, indicating strong selection of B cell antigen receptor
119 the same location over the past six millennia, indicating sub-millennia recurrence intervals over thi
121 in Siah2(-/-) mice subjected to PD-1 blockade, indicating synergy between PD-1 blockade and Siah2 los
122 isplayed more release than Syt1 mutants alone, indicating SYT7 does not mediate the residual asynchro
123 total cell-free DNA before treatment was 0.07%, indicating that ultrasensitive assays are needed for
125 after 72 h they outnumbered the control (1.2) indicating that stimulation initially inhibited growth
126 in the related species, Prunus persica (peach), indicating that artificial selection during domestica
127 e directed against the N-terminal domain (NTD), indicating that both of these regions at the top of t
128 with a pooled HR of 1.91 (95% CI: 1.34, 2.73), indicating that higher expression of miR-21 was signi
129 d to test different drugs or drug combination, indicating that 5-fluorouracil (5-FU) + irinotecan (IR
130 amma- Proteobacteria than the deeper sections, indicating that a salinity gradient exists within the
131 the proportion of progressing lesions was low, indicating that a substantial number of lesions appear
133 n addition, NKKC1 mRNA levels remained stable, indicating that ALD modulates NKCC1 protein expression
134 ction of specific changes to the outer capsid, indicating that an optimal fit between inner and outer
135 ngly correlated or anti-correlated in studies, indicating that another factor closely tied to tempera
136 UBP-310 dissociation from GluK1 homotetramers, indicating that antagonist dissociation proceeds in a
137 zed at higher rates than spores with anthrose, indicating that anthrose may serve an antiphagocytic f
138 a manner indistinguishable from wild-type D2R, indicating that arrestin recruitment can drive locomot
139 tors for cell debris in the above experiments, indicating that astrocytes stand by in case of microgl
140 ll deficiency did not impact bacterial burden, indicating that B cells only enhance susceptibility to
141 ed in exposed females and males after 28 days, indicating that brain neurochemistry had not normalize
142 d treated animals that were clustered closely, indicating that c-ART partially reversed the gut dysbi
143 rine EGA are not enriched in cattle or humans, indicating that cattle may be a more informative model
144 l gradients were evident at all ages examined, indicating that cell diversity emerges in early post-n
145 n did not reverse with a [Cl(-)](out) of 5 mm, indicating that ClC-5-mediated exchange of two Cl(-) o
146 ine Nmnat1 knockouts show embryonic lethality, indicating that complete absence of NMNAT1 activity is
147 influence transmission at PC-to-DCN synapses, indicating that conclusions based on studies of Doc2b
148 in the liver correlated with the pKa of DLNPs, indicating that DLNPs with a pKa close to 6.3 could ge
149 lows degradation with either targeting signal, indicating that domain stability and mode of targeting
150 ing activity leads to innate immune induction, indicating that Drosophila Adar, despite being the hom
151 ate of KIF1A was similar to the stepping rate, indicating that during stepping, rear-head detachment
152 iquimod-triggered psoriatic skin inflammation, indicating that E-cadherin on LC does not influence th
153 apping peak was observed on chromosome 5q35.1, indicating that each Native American ancestry allele w
154 ffspring production when allowed to reproduce, indicating that earlier mating can influence subsequen
155 PD-L1 mAb had no significant antitumor effect, indicating that early, self-activating expression of a
156 arrest was not rescued by LA supplementation, indicating that endogenous synthesis of LA is essentia
157 ime and are not correlated with bond strength, indicating that ensemble plasticity is specific to par
158 ermal phyB suppresses thermoresponsive growth, indicating that epidermal PIF4-auxin pathways are esse
159 can be different at high and low temperatures, indicating that even a well-defined genetic or pharmac
160 evel) as a predictor of body nutrient content, indicating that evolutionary history plays a crucial r
161 w) within a factor of 3 and 3.4, respectively, indicating that existing models can reliably predict C
162 s are highly variable in all three accessions, indicating that expression is not strictly coupled wit
163 GPase activity and lower sucrose in the roots, indicating that feedforward loops enhanced sink capaci
164 shows a low-intensity or absent D band for FG, indicating that FG has among the lowest defect concent
165 ly, mutation of Fig4 results in lower PI3,5P2, indicating that Fig4 is also required for PI3,5P2 prod
166 r activated BMMCs but not by TWEAK(-/-) BMMCs, indicating that Fn14 is crucial for endothelial barrie
167 missense mutations in TEM-1 were deleterious, indicating that for some proteins collateral fitness e
168 ssociated with worsen in psychomotor symptoms, indicating that future psychological interventions sho
169 from PAN-PDE4 inhibitor-induced gastroparesis, indicating that gastric retention may result from the
170 nt inducers of GVHD-induced colonic pathology, indicating that GM-CSF constitutes a nonredundant infl
171 ndent increase in lysosomal V-ATPase activity, indicating that H89 and dorsomorphin modify V-ATPase a
172 ymatic function, permit normal stratification, indicating that HDAC3's roles in this context are larg
173 e relationship between weight and temperature, indicating that high temperatures may be a constraint
174 M1 macrophages, and decreased M2 macrophages, indicating that host Wnt5a promotes an immunosuppressi
175 one another through the premalignancy cascade, indicating that increased epithelial cell expression o
176 ned, the obligate transducer of Shh signaling, indicating that Inpp5e functions within the cilium to
177 synthetic urine for two of the three sealants, indicating that ionization and hydrophilicity control
178 d by trapping the linker in the resting state, indicating that isomerization of the beta11-12 linker
180 of cells in most tissues would contain fibers, indicating that it is unlikely that the disease would
181 alone is sufficient for the generation of IBs, indicating that it plays an important role in IB forma
182 r stress inhibited YK-4-279-induced apoptosis, indicating that low-flow vessels may be uniquely susce
183 es and are frequently not direction-selective, indicating that mainly interocular comparisons serve t
184 s of terrestrial and marine origins was found, indicating that marine samples are better represented
185 cking genes required for proper SG maturation, indicating that maturation of SGs might occur in a man
186 of neutralizing antibodies on both cell types, indicating that ME is not simply deficient at cell-fre
187 yer-engaged BRCs than a transmembrane peptide, indicating that mechanisms other than domain partition
188 ic infection and the germinal center response, indicating that MHV68 may, in a B cell-intrinsic manne
189 rgence towards predictable trait combinations, indicating that morphological variation is organized i
190 is important for MTR4 expression in HCC cells, indicating that MTR4 is a mediator of the functions of
191 m in the absence of all hipBA operons or spoT, indicating that multiple pathways lead to persister ce
192 cerols were detected in both bleached mutants, indicating that mutant cells retain some plastid remna
193 xchange or stomatal conductance significantly, indicating that neither flooding itself, nor seawater
194 and experimental autoimmune encephalomyelitis, indicating that NKG2D is an important target for the a
195 alpha(1A)-adrenergic receptor from astroglia, indicating that norepinephrine acts directly on these
196 blocking the function of Pdcd4 in depression, indicating that Pdcd4 might be a new potential target
197 tion in biogenic SOA loadings over the Amazon, indicating that photolysis exerts a substantial contro
198 rozoites that additionally are not infectious, indicating that PIMMS43 is also essential for sporogon
199 significantly upregulated in the mutant mice, indicating that pre-translational splicing defects may
200 r gymnosperms between 1950-1969 and 1990-2009, indicating that previous model simulations assuming in
201 ain was hypersensitive to tenofovir treatment, indicating that PrimPol protects against tenofovir-ind
202 endent expression after reproductive maturity, indicating that pubertal processes that occur after SE
203 rom proviral PVCVs accumulated in aged plants, indicating that PVCV was activated as the host plant a
204 increase the percentage of animals colonized, indicating that QS-dependent colonization is responsiv
205 gosome-lysosome fusion inhibitor, chloroquine, indicating that Rab27b KD induces a defect in autophag
206 st one P-element insertion in a piRNA cluster, indicating that repressor alleles are produced by de n
207 ased scattering time for free charge carriers, indicating that scattering mechanisms limiting the mob
208 higher speed and performed larger tail bends, indicating that Somatostatin 1.1 inhibits spontaneous
209 ut only 21% were reported by standard culture, indicating that standard work-up provides an incomplet
210 one substitution in comparison to its removal, indicating that surface species leading to isopropanol
211 ermeability increase in response to endotoxin, indicating that targeting of DVRGLL motif within MYLK-
212 eaches the activity of the B. subtilis gyrase, indicating that the activities of enzymes containing m
213 8 g, with an encephalization quotient of 1.73, indicating that the African wild dog has a relatively
214 3-fold increase of 2-methylhopanoid abundance, indicating that the biosynthetic reaction mechanism is
215 PdL are involved in the rate-determining step, indicating that the C-H activation step may be partial
216 owing a good correlation between both methods, indicating that the cannabinoid reporter assay can be
217 ational flexibility and functional importance, indicating that the cavities facilitate functional mov
219 autophagy, and apoptosis pathway transcripts, indicating that the DAP1 risk allele mediates enhanced
220 o engage RLRs and modulate the IFN-I response, indicating that the distinction between self and non-s
221 subsets show a common vibrational fingerprint, indicating that the diverse electronic absorbers in eu
222 s in one strain can be deleterious in another, indicating that the evolutionary constraints of antige
223 stage rate, associated with bilayer formation, indicating that the first-stage reaction is more favor
225 ion by Salmonella in the murine colitis model, indicating that the HilD-dependent signaling pathway f
226 eta preceded fixations to retrieved locations, indicating that the hippocampus coordinates memory-gui
227 rease in glycated lysine residues in collagen, indicating that the imine formed between circulating g
228 onse of specific secondary structure elements, indicating that the intracellular environment affects
229 d access to inpatient penicillin skin testing, indicating that the majority of US hospitals lack suff
230 spondence with the original connectivity maps, indicating that the model recovers functional relation
231 emale humoral immune measures were unaffected, indicating that the propensity for post-mating effects
232 cells and in CL-deleted yeast crd1Delta cells, indicating that the role of CL in iron-sulfur biogenes
233 revent Gag-gRNA interactions in the cytoplasm, indicating that the two ZFs display redundant roles in
234 PV E6 more broadly impairs cellular signaling, indicating that the viral protein dysregulates the HP.
235 ion of CpxA despite its asymmetric structures, indicating that these asymmetric domain arrangements a
237 mutants was higher in neutropenic mouse lungs, indicating that these genes encode proteins that prote
238 y poor correlations for certain types of LCDs, indicating that these scales may not capture secondary
240 sive epigenomic signatures in the naive state, indicating that they are poised for expression prior t
241 nriched in DCB versus TCE enrichment cultures, indicating that they may play a role in dechlorination
242 tically higher than expected under neutrality, indicating that this difference may have been driven b
243 receptor potential vanilloid type-1 receptors, indicating that this effect was caused by acid activat
244 pairs remained invariant across activity type, indicating that this measure could be employed as a ro
245 hibited differential sakuranetin accumulation, indicating that this metabolic diversity predates rice
246 are compatible with results in the literature, indicating that this or similar systems will be useful
248 the former but was dispensable for the latter, indicating that TRAF6-mediated polyubiquitination and
249 the expression of cell cycle-associated genes, indicating that tumor growth and cell proliferation we
251 ere enriched in the polysomes of upf1 mutants, indicating that UPF1/NMD suppresses the translation of
252 p11 homozygous null embryos die prior to E8.5, indicating that Wbp11 is essential for development.
253 but phosphorylated variants of CHT7 persisted, indicating that yet-unidentified residues within CHT7
254 ovine Y sequence assembly accounted for 46.49%, indicating the success in the ovine Y chromosome isol
255 nt of the initial configuration of the ligand, indicating the ability of the 18-membered P(4)N(2) mac
256 ts of a 1-in-25 year event exceed >pound 200m, indicating the additional investments justifiable to m
257 n spectra and elution patterns of the samples, indicating the appropriateness of the SVD-based proced
258 presented here to previously reported systems, indicating the capability for substantially enlarging
259 constant with coherent tunneling down to 10 K, indicating the carbon paint does not add spurious ther
260 pathway leads to postreceptor desensitization, indicating the critical balance between normal signali
262 ll as the potentiated corticosterone response, indicating the dependence of the memory enhancement on
263 AMPK deficiency under the conditions examined, indicating the essential role of this kinase and its t
264 n lymphocyte recirculation through the spleen, indicating the existence of separate entry and exit ro
265 on of Ag nanocubes and nanowires respectively, indicating the faster reducing agent formed kineticall
266 lly shown in hematologic malignant K562 cells, indicating the generality of the observed EMD effects.
267 s well as Src-dependent Cav-1 phosphorylation, indicating the importance of CSD in the interaction.
268 ure patients without atherosclerotic diseases, indicating the importance of identifying underlying me
269 vide new insights for rational vaccine design, indicating the importance of preserving both the globa
270 to a loss of induced PIP2 clustering in MACA, indicating the importance of protein multimerization.
271 ants' performance in a semantic judgment task, indicating the importance of this higher-order topolog
272 erobic conditions showed very low correlation, indicating the independence of their genetic control.
273 s show distinct risk factor trend differences, indicating the need for contemporary tailored preventi
274 o 8 was assigned at every pixel of these maps, indicating the number of the surrounding pixels having
275 symptoms than those with high meibum delivery, indicating the pivotal role of meibum secretion in ocu
276 gher arbuscule densities relative to controls, indicating the potential to manipulate the relative pr
277 ptic afferent terminals is likely to increase, indicating the presence of a previously unknown degree
278 y estimated in acellular hemoglobin solutions, indicating the presence of diffusional barriers in int
280 as confirmed in a human hepatoblast cell line, indicating the relevance of this pathway for human liv
281 carboxylases that are poorly activated by Rca, indicating the side chains of these residues form a cr
282 ,5-oxadiazole 2-oxide subunit was synthesized, indicating the stability of prepared compounds toward
283 rease for large oligonucleotides was observed, indicating their alignment over the stationary phase.
284 nsin homologous genes were all down-regulated, indicating their potential contribution to the phenoty
285 which are frequently mutated in skin cancers, indicating their potential role as founding mutations
286 overall promising pharmacokinetic properties, indicating their therapeutic potential for the treatme
287 host species, often in striking fashion [1, 2], indicating there is selection on parasite morphology
288 mutant, which lacks the extracellular domain, indicating these mutations act on the transmembrane (T
289 ods, and 'sphingomyelins' by all but Wilcoxon, indicating these pathways significantly associate with
290 computationally identified for beta-TaFeTe(4), indicating they may contribute to the transport behav
292 to two dramatically different types of cells, indicating this approach could be broadly applicable.
293 rmoxic ventilation with acclimatization to CH, indicating this is a distinct mechanism from the incre
295 relies on the preceding BM fibril deposition, indicating two distinct but interdependent functions.
296 e individuals and within the same tumor sites, indicating ubiquitous variability in immune cell infil
297 ds well beyond its overall genetic background, indicating unexpectedly weak correlation between morph
298 rnal-beam radiotherapy was cell-line-specific, indicating varying levels of intrinsic radiosensitivit
299 -C bond lengths differ by only 0.028 angstrom, indicating virtually complete electron delocalization.
300 urces were negatively related to resource C:P, indicating widespread P limitation in these detritus-b