ライフサイエンスコーパス: increased bone mass

1 hese data, JDP2(-/-) mice were found to have increased bone mass.

2 show decreased lysosomal gene expression and increased bone mass.

3 ion, which results in decreased body fat and increased bone mass.

4 istance to PPARgamma is dominant, leading to increased bone mass.

5 As a consequence, Ciz-deficient mice develop increased bone mass.

6 overexpressing a soluble receptor for leptin increased bone mass.

7 a single allele of OF45 caused significantly increased bone mass.

8 Ablation of OF45 resulted in increased bone mass.

9 tivation of osteoclastogenesis, resulting in increased bone mass.

10 Vav3-deficient mice have increased bone mass and are protected from bone loss ind

11 n of cannabinoid type 1 (CB1) receptors have increased bone mass and are protected from ovariectomy-i

12 deletion of Phd2 in chondrocytes resulted in increased bone mass and bone formation rate (normalized

13 Mice lacking RAGE had increased bone mass and bone mineral density and decreas

14 CD47(-/-) mice had increased bone mass and defective osteoclast function in

15 formation, improved bone microarchitecture, increased bone mass and enhanced mechanical properties i

16 rostin antibody and zoledronic acid combined increased bone mass and fracture resistance when compare

17 Smad3+/- mice had increased bone mass and matrix properties, suggesting th

18 signaling in mature osteoblasts resulted in increased bone mass and protection from bone loss in old

19 eceptor signaling in osteocytes that exhibit increased bone mass and remodeling, recognized skeletal

20 mBMPR1A treatment also increased bone mass and strength in mice with bone loss

21 eletal impact, female HeyL null mice display increased bone mass, and Hey2 inactivation is developmen

22 lls or in differentiated osteoblasts, showed increased bone mass as adults.

23 Despite their increased bone mass, beta3-null mice contain 3.5-fold mo

24 OA patients have increased bone mass, but no corresponding decrease in fr

25 We confirmed the increased bone mass caused by inhibition of osteoclast a

26 C5aR1(-/-) and C5aR2(-/-) mice displayed an increased bone mass compared to wild-type controls due t

27 Increased bone mass could partially be rescued by bone m

28 The functional outcomes considered were increased bone mass, decreased rates of bone loss, impro

29 tion of central ERalpha signaling results in increased bone mass, demonstrating that the balance betw

30 t low oral dose of 1 (mg/kg)/day body weight increased bone mass density and volume, expression of os

31 However, a second phenotype of significantly increased bone mass developed by 2 months, which continu

32 Shn3 display adult-onset osteosclerosis with increased bone mass due to augmented osteoblast activity

33 tion of Atp6v0d2 in mice results in markedly increased bone mass due to defective osteoclasts and enh

34 We showed significantly increased bone mass in 30-d SPI-fed young rats compared

35 lower spacing between trabeculae as well as increased bone mass in both males and females compared t

36 ation of giant, nonresorbing osteoclasts and increased bone mass in male mice and protected female mi

37 pectively, in an osteoblast-specific manner, increased bone mass in mice.

38 We propose that the increased bone mass in nestin-ERalpha(-/-) mice is media

39 osteogenesis by stromal cells in culture and increased bone mass in osteoporotic mice in vivo.

40 The increased bone mass in the Foxo-deficient mice was accou

41 inc finger protein Schnurri-3 (Shn3) display increased bone mass, in part, attributable to augmented

42 terized by reduced bone mass (osteoporosis), increased bone mass (osteopetrosis), or abnormalities in

43 he current study, we postulated that IGFBP-2 increased bone mass partly through the activity of its h

44 mice develop osteopetrosis characterized by increased bone mass, reduced medullary cavity space and

45 In intact tibiae, ALN increased bone mass significantly more than PTH did.

46 Increased bone mass was associated with a reduction in t

47 lous bone histomorphometry revealed that the increased bone mass was the result of increased osteobla

48 Loss of SRC-2 resulted in increased bone mass, with SRC-2 KO mice having 80% highe