ライフサイエンスコーパス: methylmalonic acid

1 total transcobalamin, total haptocorrin, and methylmalonic acid.

2 ular mitochondrial inhibitor and neurotoxin, methylmalonic acid.

3 th higher concentrations of homocysteine and methylmalonic acid and higher odds ratios for cognitive

4 w serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels.

5 the C-H and C-N modulated CSA experiments on methylmalonic acid and N-tBoc-glycine, respectively.

6 e highest concentrations of homocysteine and methylmalonic acid and the lowest concentration of holot

7 eficiency who received treatment (15 of 21), methylmalonic acid and total homocysteine levels decreas

8 sorders characterized by the accumulation of methylmalonic acid and/or homocysteine in blood and urin

9 Elevated methylmalonic acid and/or total homocysteine are sensiti

10 lasma total vitamin B-12, 3 studies measured methylmalonic acid, and 6 studies measured total homocys

11 rum and red blood cell folate, vitamin B-12, methylmalonic acid, and homocysteine concentrations amon

12 ean pretreatment values for serum cobalamin, methylmalonic acid, and homocysteine were, respectively,

13 the amount of B12 bound to TCII (holoTCII), methylmalonic acid, and homocysteine, in 128 healthy old

14 elevation of the metabolites, homocysteine, methylmalonic acid, and the ligand, transcobalamin II, i

15 serum concentrations of total vitamin B-12, methylmalonic acid, and total homocysteine are all effec

16 Serum levels of vitamin B12, folate, methylmalonic acid, and total homocysteine measured befo

17 Serum levels of vitamin B(12), folate, methylmalonic acid, and total homocysteine were assayed

18 n status (defined by low cobalamin, elevated methylmalonic acid, and/or elevated homocysteine concent

19 ry results were significantly raised urinary methylmalonic acid compared with age-matched controls (p

20 n B-12 concentration < 148 pmol/L or a serum methylmalonic acid concentration > 210 nmol/L-the maximu

21 n B-12 concentration <148 pmol/L or a plasma methylmalonic acid concentration > or =210 nmol/L, the p

22 re, each 2-fold increment in homocysteine or methylmalonic acid concentration was associated with a d

23 with vitamin B-12 was associated with lower methylmalonic acid concentrations (P < 0.001).

24 Mean serum vitamin B-12 and methylmalonic acid concentrations did not differ; howeve

25 In addition, mean methylmalonic acid concentrations were significantly low

26 ed blood cell folate, serum homocysteine, or methylmalonic acid concentrations.

27 and beta-carotene and lower homocysteine and methylmalonic acid concentrations.

28 vitamin B-12 deficiency with elevated serum methylmalonic acid concentrations.

29 one users also had significantly lower serum methylmalonic acid concentrations.

30 ither vitamin B-12 or folate deficiency, and methylmalonic acid for detection of vitamin B-12 deficie

31 B-12 function (vitamin B-12 <200 pmol/L and methylmalonic acid >0.27 micromol/L) in the total group

32 in B-12 concentrations <150 pmol/L, or serum methylmalonic acid >376 nmol/L.

33 Homocysteine, methylmalonic acid, holotranscobalamin, ratio of holotra

34 One year after transplant, urine methylmalonic acid indicates good vitamin B12 absorption

35 using markers such as holotranscobalamin and methylmalonic acid, it has been found that cognition is

36 depression, had a significantly higher serum methylmalonic acid level and a nonsignificantly lower se

37 2 level less than 221 pmol/L and an elevated methylmalonic acid level; 2) a serum vitamin B12 level l

38 The higher serum cobalamin and lower serum methylmalonic acid levels at 4 months posttreatment in t

39 alization of elevated total homocysteine and methylmalonic acid levels may prevent the development of

40 Methylmalonic acid may contribute to neuronal injury in

41 tus [ie, plasma vitamin B-12 < 148 pmol/L or methylmalonic acid (MMA) > 210 nmol/L] with respect to a

42 racteristics of metabolic biomarkers such as methylmalonic acid (MMA) and holotranscobalamin II, whos

43 exists at which the relation between plasma methylmalonic acid (MMA) and SB-12 changes slope to diff

44 al, cognitive, routine diagnostic, and serum methylmalonic acid (MMA) and total homocysteine (tHcy) t

45 olate, serum vitamin B-12, homocysteine, and methylmalonic acid (MMA) concentrations in US children b

46 12, and plasma total homocysteine (tHcy) and methylmalonic acid (MMA) in the US population.

47 Methylmalonic acid (MMA) is a by-product of propionic ac

48 sis on the association between rs1801198 and methylmalonic acid (MMA) lacked statistical power.

49 Urinary methylmalonic acid (MMA) may be a more informative bioma

50 anscobalamin, total homocysteine (tHcy), and methylmalonic acid (MMA) were measured before and after

51 B(12) status, total homocysteine (tHcy) and methylmalonic acid (MMA), among adult participants in ph

52 min B-12, holotranscobalamin (holoTC), tHcy, methylmalonic acid (MMA), and folate with the use of lin

53 amin B-12, plasma total homocysteine (tHcy), methylmalonic acid (MMA), and holotranscobalamin into on

54 However, diagnostic algorithms using Cbl, methylmalonic acid (MMA), and homocysteine (HCys) measur

55 tus used in past NHANES--serum vitamin B-12, methylmalonic acid (MMA), and total homocysteine (tHcy)-

56 parison of baseline serum cobalamin, folate, methylmalonic acid (MMA), total homocysteine (tHcy), and

57 Methylmalonic acid (MMA), total homocysteine, and other

58 ma cobalamin, total homocysteine (tHcy), and methylmalonic acid (MMA).

59 n and elevated total homocysteine (tHcy) and methylmalonic acid (MMA).

60 plasma total homocysteine (tHcy), and plasma methylmalonic acid (MMA)].

61 the use of vitamin B-12 than with the use of methylmalonic acid (MMA; 3-26% and 2-6%, respectively).

62 vels of cobalamin (normal, 200 to 900 pg/mL) methylmalonic acid (normal, 73 to 271 nmol/L), and homoc

63 ne, kynurenine, leucine, lysine, methionine, methylmalonic acid, ornithine, phenylalanine, proline, s

64 in the brain was evident from the increased methylmalonic acid (P<0.01-0.04), homocysteine (P<0.01),

65 , show failure to thrive, and show increased methylmalonic acid, propionylcarnitine, odd chain fatty

66 ene of Pseudomonas aeruginosa, which encodes methylmalonic acid semialdehyde dehydrogenase (MSDH) and

67 rum vitamin B-12, total homocysteine (tHcy), methylmalonic acid, serum folic acid, and 5-methyltetrah

68 ion test and measurement of homocysteine and methylmalonic acid, to cobalamin status has identified t

69 mentation may be effective in lowering serum methylmalonic acid values in the elderly.

70 s of vitamin B-12, folate, homocysteine, and methylmalonic acid were measured.

71 Methylmalonic acid, which is formed from the MCM substra

72 as associated with elevated homocysteine and methylmalonic acid, which were reduced by folate and vit

73 f folate, cobalamin, total homocysteine, and methylmalonic acid with cognitive performance at 2 occas

74 elderly population as documented by elevated methylmalonic acid with or without elevated total homocy

75 The use of serum vitamin B-12 and plasma methylmalonic acid would provide continuity with past NH