ライフサイエンスコーパス: recreate

1 m motion photogrammetry (SfM) was applied to recreate 3D representations of video transects along the

2 t nanolithography technologies are unable to recreate 4D nanostructures with the chemical or architec

3 ontext of a different response regulator, we recreated 51 analogous amino acid substitutions at corre

4 h is to use our understanding of a system to recreate a biological function with specific properties.

5 esidues between DENV serotypes and partially recreate a complex antibody epitope, while retaining vir

6 om widely used high-throughput techniques to recreate a given phenotype and ultimately to make predic

7 Cancer cells in the biomimetic matrix recreate a hypoxic environment that affects their growth

8 Multimers of the 19-base-pair (bp) block recreate a Krml1-like pattern in r5/r6, but the 45-bp bl

9 In human CD34(+) cells, ABE8 can recreate a natural allele at the promoter of the gamma-g

10 Efforts to recreate a prebiotically plausible protocell, in which R

11 ry phenotype combined with their capacity to recreate a secondary tumor in a distant tissue.

12 habitat, namely in the bulge, could help to recreate a similar melanoma-suppressive signaling enviro

13 C57BL/6 mice to determine if these intervals recreate a Sjogren's syndrome (SS)-like phenotype.

14 ectronic health records from 1997 to 2016 to recreate a UK population-based cohort of 1.3 million wom

15 critical periods of craniofacial development recreated a continuum of HPE-related defects.

16 All models successfully recreated a majority of the variation in current wetland

17 sgene onto a Gbx2-null mutant background and recreated a new Otx2/Gbx2 border in the anterior hindbra

18 annel gating and the other for SecA binding, recreates a functional translocation unit.

19 This "lineage infidelity" recreates a state akin to transient wound repair that pe

20 evance of the mutation was also validated by recreating a lymphatic phenotype in a zebrafish model, w

21 topographic connections in the optic tectum, recreating a two-dimensional map of the visual field in

22 However, it is not known whether ICMS could recreate active texture exploration-the ability to infer

23 ffects could be reversed and acute rejection recreated after adjunctive treatment of rats with recomb

24 sual cortex, in which a stimulus sequence is recreated after only a subset of the visual input is pro

25 -splicing at ratchet points--5' splice sites recreated after splicing.

26 However, it is not possible to recreate all cellular aspects of the bone marrow microen

27 ernal sensory organ formation and is able to recreate an ectopic proneural field.

28 We find that the transposase MuA can recreate an essentially similar topology on nicked subst

29 l in the debate over whether Congress should recreate an Office of Technology Assessment (OTA).

30 In this issue of Neuron, de Calignon et al. recreated an early stage of neurofibrillary tangle patho

31 h several case studies that use its tools to recreate and expand upon the published analysis of cance

32 idely accessible simple preclinical model to recreate and explore underpinning pathways of lethal dis

33 This review represents my best effort to recreate and memorialize events that occurred 44 years a

34 dvent of high-intensity lasers enables us to recreate and study the behaviour of matter under the ext

35 A number of approaches have been taken to recreate and to study the role of genes associated with

36 these protein engineering principles, while recreating and extending natural functions.

37 es form part of technologies that attempt to recreate animal and human physiological functions on a c

38 the soma and dendrites of ganglion cells to recreate antagonistic center-surround receptive field in

39 vitro, largely because of the complexity of recreating appropriate environmental signals in culture.

40 ith these, the selected heterozygotes can be recreated as F1 hybrids, greatly increasing the number o

41 SEMA3B to normal CTBs inhibited invasion and recreated aspects of the PE phenotype.

42 the first dramatic successes in mouse models recreating aspects of Alzheimer disease (AD) were report

43 samples gathered from study participants who recreated at Boqueron Beach, Puerto Rico.

44 sest to the carboxyl terminus of p90ATF6, we recreated ATF6(f).

45 electrodes to stimulate auditory neurons and recreate auditory sensations in deaf people.

46 ciation curve for mouse blood was accurately recreated based on measurements during deoxygenation of

47 The CD200(+) CD45(-) BCC subpopulation recreated BCC tumor growth in vivo with typical histolog

48 uter simulations using adhesive dynamics can recreate bead rolling dynamics and show that the mechano

49 ed "nucleation site." We show that our model recreates both the extent of spreading and the presence

50 eed to be obliterated and midfacial contours recreated, but swallowing function, phonation, and masti

51 of AT1 receptor activation by Ang II can be recreated by a reciprocal exchange of aromatic and amide

52 reducing gut microbes using antibiotics and recreated by adding back Lactobacillus plantarum We sugg

53 rait differences in ancient hybrids could be recreated by complementary gene action in synthetic hybr

54 is a developmental ground state that can be recreated by direct reprogramming.

55 Human EPHX2 mutants were recreated by site-directed mutagenesis and fused downstr

56 Each mutation was individually recreated by site-directed mutagenesis and studied in tr

57 und in databases or reported elsewhere, were recreated by site-directed mutagenesis and were assessed

58 Pluripotency can be recreated by somatic cell reprogramming.

59 However, the 5J7 epitope was only partially recreated by transplantation of the core residues becaus

60 mediated TLR4-driven local inflammation, and recreated cardinal features of liver IR injury.

61 rdiac anatomy at different depth planes, and recreate casts of blood flow of the chambers and great v

62 Strikingly, inactivation of Lmx1a and Lmx1b recreates cellular features observed in Parkinson's dise

63 ion rate for selectin bonds, we were able to recreate characteristics of the shear threshold effect s

64 Our feedback control model can recreate chromosome movement from prometaphase to anapha

65 he great star coral Montastraea cavernosa, a recreated common ancestor of green and red proteins turn

66 as '3D magnetic printing', has enabled us to recreate complex bioinspired reinforcement architectures

67 rtunity to overcome previous limitations and recreate critical elements of the in vivo microenvironme

68 yonic stem cell-derived cardiomyocytes could recreate de novo myocardium with higher efficiency, alth

69 extensive simulation scheme was developed to recreate different scenarios of copy number changes and

70 Here, using microfluidic devices to recreate discretely organized neuronal connections, we s

71 of one original light chain allele, thereby recreating dual receptor expression on these surviving B

72 self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear.

73 ack resources, simulated deer were unable to recreate empirical migratory routes.

74 ability of populations of simulated cells to recreate experimental expression data and the effects of

75 ng approach to produce model fits that could recreate experimental outcomes.

76 inal cells were assessed by their ability to recreate experimental patterns of prostate cell prolifer

77 region of the prostate duct was able to best recreate experimental patterns of prostate proliferation

78 This is spurring interest in recreating extracellular influences in simplified forms,

79 We have been successful in reproducibly recreating functionally normal breast tissues from reduc

80 We used these composites to recreate fundamental folded patterns, derived from compu

81 ental population processes have successfully recreated general species-abundance patterns without acc

82 mal model to design an ex vivo platform that recreates genetic susceptibility to T-cell-mediated dama

83 We have recreated glutamine-repeat disease in Drosophila using a

84 Furthermore, recreating granule cell hyperexcitability in control mic

85 Recreating heterotypic cell-cell interactions in vitro i

86 ASOs represent a new and powerful tool for recreating HGPS pathophysiology in wild-type cells.

87 We recreated his experiment 47 years later using a contempo

88 the basic PF are more capable of faithfully recreating historical influenza incidence time series, w

89 This deficiency has hampered efforts to recreate human liver diseases in mice, and has cast doub

90 stablishment of effective protocols aimed at recreating human liver tissue in vitro.

91 employed a microfluidic co-culture system to recreate important interactions in the liver stem cell n

92 , investigators have unsuccessfully tried to recreate in experimental animals the cardiovascular comp

93 es of DNA synthesis have made it possible to recreate in principle all known viruses independent of n

94 These substitutions recreate in RNase A the basic surface found in bovine se

95 maining challenge is to induce human iPSC to recreate in vitro key structural and functional features

96 We have undertaken to recreate in vitro the evolutionary competition between v

97 Recently, selectin-mediated rolling was recreated in a cell-free system; it was shown that sialy

98 Thus, an engineered signalling cascade is recreated in an artificial cellular system.

99 ed expression of HC genes that can easily be recreated in any laboratory from any mouse of interest.

100 sions and recruit ACAP effectively, could be recreated in either untransfected cells or cells express

101 rase II complexes to arrest may therefore be recreated in promoter-distal complexes simply by shorten

102 The mutations of three of these mutants were recreated in the clinical serotype A strain H99: deletio

103 Pathological mutations were recreated in the Dictyostelium protein and expressed in

104 le contexts underlying a single event can be recreated in the same network.

105 e used to monitor the public health risks of recreating in surface waters.

106 subunit residues into the gamma2 subunit to recreate, in alphabeta gamma receptors, the proton modul

107 dataset and is considerably more accurate in recreating individual axonal morphologies.

108 ic medical center; videotapes were made in a recreated intensive care unit environment using a high-f

109 t has been distributed it is not possible to recreate it by LOCC.

110 oth in establishing liver microstructure and recreating it after injury.

111 exact details of those events, but rather by recreating its own selective pictures based on cognitive

112 rization and melting alone are sufficient to recreate jamming and rescue.

113 -1(Hi) CD4+, but not TIM-1(Lo) CD4+ T cells, recreated liver IRI in RAG(-/-) mice.

114 er of WT but not TIM-4-deficient BMM readily recreated local inflammation response/hepatocellular dam

115 Mechanisms to recreate many anthocyanin blue hues in nature are not fu

116 Our simulations qualitatively recreate many empirical patterns and lead to a descripti

117 lf-organize into embryo-like structures that recreate many features of early mouse development.

118 These cultures effectively recreate many of the physiological features of the tumou

119 ndrites induces robust dendritic growth that recreates many features of uninjured dendrites, includin

120 hysiologically relevant in vitro models that recreate mechanical loading conditions seen in both norm

121 yers lack a sufficient membrane reservoir to recreate membrane budding and fission events.

122 , called primitive lung-in-a-dish (PLiD), to recreate metastatic disease using primary and establishe

123 carcinoma cells in polymeric scaffolds that recreated microenvironmental characteristics representat

124 Current approaches to recreate morphogenetic processes in vitro rely on poorly

125 ogues, but whether these classic systems can recreate morphology in the absence of a preexisting temp

126 cesses individually and that, when combined, recreate most of the behaviors of chemotactic cells.

127 of At1g01050 using a seed-preferred promoter recreated most features of the lo15571 seed phenotype, i

128 of CD34(+) cells with the b3a2-BCR/ABL cDNA recreates most, if not all, phenotypic abnormalities see

129 easured, predicted, and finally artificially recreated multimodal cues from individual flowers visite

130 Site-directed mutagenesis has been used to recreate mutations observed in individuals with TCS.

131 By closely recreating natural OM behavior, this model provides a mu

132 culative, owing to the extreme difficulty in recreating neutral matter-antimatter plasmas in the labo

133 Our integrated model recreates neutrophil arrest within physiological timesca

134 ve WT, but not from TIM-3 Tg donors, readily recreated OLT damage in otherwise IR-resistant RAG(-/-)

135 ed on various animal models that are able to recreate one or more conditions or elevate risk factors

136 rstood because the structure is difficult to recreate or study in vitro.

137 in the precision of finding proteins of the recreated pathways compared to random simulation.

138 tested whether reduced DAT functioning would recreate patterns of deficient decision making of BD pat

139 ionary device that is capable of storing and recreating photonic qubits with a higher fidelity than a

140 (nASI) has all the determinants required to recreate proper neural-specific RNA processing seen with

141 utomated text mining has been widely used in recreating protein interaction networks, as well as in d

142 in MS B cells is the potential to accurately recreate recombinant Abs from these overrepresented H an

143 rIL-2 or freshly alloactivated spleen cells recreated rejection in thymectomized, but not euthymic,

144 th cytolytic anti-CD4, but not anti-CD8, mAb recreated rejection of test cardiac allografts with simu

145 describe beta-sheet formation in membranes, recreated remarkably well the unusual shape and concentr

146 nal method our group has shown to accurately recreate rolling dynamics, we include a generic, tunable

147 the novel ChainRank method was evaluated on recreating selected signalling pathways from a human pro

148 in target affinity and then combine them to recreate several of the mechanisms employed by nature to

149 OCN014 recreated signs of disease in experimentally infected co

150 Specifically, we recreated skeletal muscle specific signaling networks in

151 In an attempt to recreate some features of the complex set of cues arisin

152 agenesis in mice infected with Plasmodium to recreate some of the hallmark characteristics of Burkitt

153 sting model of auxin transport sufficient to recreate spiral phyllotactic patterns and find previousl

154 n determined on a range of media designed to recreate stresses experienced in microbial habitats or a

155 ost current tooth engineering systems cannot recreate such developmental processes.

156 ion (STED) imaging of collective samples and recreated superresolved relative localizations of eight

157 with two shorter counterstrands designed to recreate the above duplex damage site.

158 RNA microhelices that recreate the acceptor stems of transfer RNAs are charged

159 pase-8 alone are necessary and sufficient to recreate the adhesive and biochemical phenotypes observe

160 RNA minihelices that recreate the amino acid acceptor domain of the two-domai

161 DFL16.1 sequence could use N nucleotides to recreate the amino acid sequence associated with the cla

162 rticipants' memory was tested by having them recreate the appearance of the object features using a c

163 of DGAT1 in skeletal muscle is sufficient to recreate the athlete's paradox and illustrates a mechani

164 he program Rosetta to predict sequences that recreate the authentic fold of thioredoxin.

165 We were able to recreate the author's findings to a high degree, thus pr

166 tation used to stabilize the enzyme does not recreate the balance of conformational flexibility evolv

167 Our biomimetic cilia recreate the beat shape of embryonic nodal cilia, simult

168 t a specific histone-DNA concentration could recreate the behavior observed in two-cell embryos: acqu

169 We recreate the breast tumor mechanical environment by cont

170 -dimensional (3D) epithelial culture systems recreate the cardinal features of glandular epithelium i

171 e, simultaneous chemoattractant cues and can recreate the cellular response to combinations of tempor

172 models have been developed in an attempt to recreate the chronic HF phenotype that arises following

173 In order to recreate the clinical space lost to caries or trauma nec

174 oduce the changes in minor groove widths and recreate the curved Fis-bound DNA structure.

175 Furthermore, we recreate the deletion formation process in vitro using o

176 A mixture of Nd and Cd fails to recreate the DNA looping effect of native DnaD but produ

177 ging of Drosophila embryos have been used to recreate the dynamic activities of a complex transcripti

178 However, few simulators exist to recreate the dynamic interactions during real tool use,

179 course study and the simulation was found to recreate the dynamics and time scale of the systems resp

180 l metamorphism in the crust in the effort to recreate the effect of the LHB on the Earth as a whole;

181 or progression, mutation rates sufficient to recreate the epidemiology of colorectal cancer were esti

182 Here, we recreate the evolutionary pathway between two modern hum

183 To faithfully recreate the features of the human neurodegenerative dis

184 New synthetic materials that also recreate the fibrous structural hierarchy of natural mat

185 small number of plane projections is used to recreate the full multidimensional spectrum in the famil

186 bio-inspired artificial cell components that recreate the function of key cellular and physiological

187 Our system appears to recreate the HDAC-independent component of MeCP2-mediate

188 is an acute need for biomaterial tools that recreate the heterogeneous brain-tumor microenvironment.

189 p micro-engineered tissue platforms that can recreate the highly inhomogeneous tissue microstructures

190 sed small molecule screen was established to recreate the hypothesized interactions involving newly s

191 last glacial cycle (the past 130,000 years) recreate the ice core record and capture the late Holoce

192 odopsin-expressing, grafted neurons does not recreate the impairment, indicating that its reversal is

193 t simulated competition may be sufficient to recreate the in vivo frequency dependence of the CaM-dep

194 care unit was equipped and staffed to nearly recreate the intensive care environment.

195 Computer simulations using the 2S3B model recreate the ion concentration dependencies of single-ch

196 ng to this theory, laypeople can intuitively recreate the laws of familiar and unfamiliar cultures, e

197 To recreate the local presentation of Wnt proteins often se

198 st to the Galton-Watson model, our model can recreate the log-normal segment-length distribution of t

199 e molecular ion of each hydrocarbon group to recreate the magnitude and mass spectra of the chromatog

200 Here we accurately recreate the mechanical shedding of L-selectin and its e

201 s show that overexpression of LSP1 alone can recreate the morphologic and motile defects seen in NAD

202 erentiation and identify the conditions that recreate the native bone marrow environment, combinatori

203 tial of MSC and identify the conditions that recreate the native cartilage environment, we used time-

204 s are noninfectious viruslike particles that recreate the native envelope glycoprotein structure and

205 prompting a number of approaches designed to recreate the native glycoprotein complex that exists on

206 onstraints and delayed alignment was able to recreate the observed spatial actor-reactor patterns.

207 Particle-based simulations recreate the observed trends, suggesting that cell divis

208 To recreate the patient's heterozygous genotype, we perform

209 vasion, we used O2-controllable hydrogels to recreate the physiopathological O2 levels in vitro.

210 Here, using tomographic data, we recreate the plate-tectonic geometry of the subducted Na

211 this way, the review process was designed to recreate the presentation of information in a prospectiv

212 id carrying the three attP sites was used to recreate the process of tripartite ICE integration and t

213 Both models recreate the progressive adult-onset dysfunction and deg

214 e explanation is that the immunogens fail to recreate the proper molecular environment in which the e

215 een demonstrated in a number of systems that recreate the requisite topological conditions.

216 lpha-syn into the OB of wild-type mice would recreate the sequential progression of Lewy-like patholo

217 Our ability to recreate the shear threshold effect in a cell-free syste

218 culate and brainstem terminals was needed to recreate the size distribution of the parent RD terminal

219 n between contractile cells is sufficient to recreate the spatial rearrangement of traction forces ob

220 major work on models that aim to capture and recreate the structure and dynamics of scientific evolut

221 bitors of protein-protein interactions is to recreate the three-dimensional arrangement of side chain

222 e also being increasingly utilized to better recreate the tissue microenvironment and better understa

223 To recreate the transition from rolling to firm adhesion, w

224 We developed a microfluidic-based assay to recreate the tumor-vascular interface in three-dimension

225 rom two to 42 capsid protein molecules) that recreate the various surfaces in infectious capsids.

226 Notably, rVSVDeltaG*/BDVG recreated the cell tropism and entry pathway of bona fid

227 We recreated the corticostriatal circuit in microfluidic ch

228 ng lymphopenia during Aire turnoff in adults recreated the disease, which, conversely, could be ameli

229 Such in utero androgen excess recreated the dyslipidaemia and hormonal profile observe

230 urthermore, treatment of T cells with PGE(2) recreated the effects seen with infected supernatant.

231 utative causative mutations in one clone and recreated the evolved phenotype in the ancestral strain.

232 Bone marrow transplantation recreated the haemopoietic phenotype of increased circul

233 e with apoptotic cells, we selected one that recreated the major serum specificity for apoptotic cell

234 teraction patterns created by the model only recreated the observed interactions, i.e. chases, and be

235 of the sadA gene by homologous recombination recreated the original mutant phenotype.

236 The third study recreated the original operant discrimination, and selec

237 Xenografts of CD133+ SCCas recreated the original SCCa tumor histology and organiza

238 a-hemorrhagic shock lymph into naive animals recreated the RBC changes observed after actual trauma-h

239 Transcription of these plasmids in cells recreated the replication of PaV RNA1 and RNA2, synthesi

240 2+ was replaced by water in the active site, recreated the salt bridges and hydrogen-bonding patterns

241 on-silenced subline through in vitro culture recreated the silenced phenotype of T(3)31 and the molec

242 RCS-10 recreates the 100% incidence seen in (NZOxNON)F1 males,

243 In contrast, an aminoacyl RNA fragment that recreates the 3'-side of the tRNA acceptor stem has a mu

244 This TIPS mutation recreates the biotechnology-engineered commercial first

245 tin and the lamina are added, the same model recreates the conventional nuclear organization.

246 The model recreates the dependence on substrate stiffness of the t

247 within a corral) on the order of 10(3)-10(4) recreates the experimentally measured difference in diff

248 A CaMV35::GR transgene recreates the Gr/Nr-2 mutant phenotype but does not lead

249 tem allows a greater freedom of movement and recreates the hand-eye coordination and three-dimensiona

250 xpression in a novel organotypic system that recreates the molecular and microenvironmental context i

251 This model takes real images as input and recreates the observed topography of human disparity sen

252 Immunopurified tau from these mice recreates the original strains in culture.

253 It also recreates the phenomenon of cell decoupling, in which ce

254 Reduction of the magnitude of this current recreates the reduction in SFA the shift from a type 2 t

255 and sensory and sympathetic impairments, and recreates the same tissue-specific mis-splicing defect s

256 In conclusion, our tree recreates the standard phylogeny of the N, M, L0/L1, L2,

257 This study demonstrates the feasibility of recreating the cartilage and epithelial portion of the t

258 e also discuss current technical hurdles for recreating the cell-type complexity and spatial architec

259 These results show the utility of recreating the cellular environment of the developing hu

260 stabilize GB1, highlighting the challenge of recreating the cellular interior.

261 iously established macroscopic tumor nodule, recreating the clinical scenario of residual microscopic

262 ting all the data to a single kinetic model, recreating the condition-dependent shift in rate-limitat

263 nstituted entirely from purified components, recreating the connection between DNA and microtubule.

264 the central role of ASCO in these events and recreating the dialogue between members of the two field

265 hes to stimulate therapeutic angiogenesis by recreating the embryonic vascular microenvironment using

266 ecies include coculture with other bacteria, recreating the environment in the laboratory, and combin

267 By recreating the exon 3 duplication mutation in a wild-typ

268 ers, and establish a basis for animal models recreating the FSHD transcriptome.

269 However, recreating the function of a naturally complex system wi

270 Recreating the functional principle of such systems and

271 uracy of artificial IT were confirmed by (i) recreating the low threshold calcium potential (LTCP) wi

272 is also modulated by presentation of a movie recreating the mouse's visual experience during natural

273 eral neuropathy, and a mouse model precisely recreating the mutation was produced.

274 Recreating the properties of skin using electronic devic

275 single amino acid replacement is capable of recreating the range of functions that can be achieved b

276 s than in the loss of species, for we cannot recreate them.

277 patterns by computer simulation, and then by recreating them in the laboratory with high fidelity.

278 whether different concentrations of activin recreate these different anteroposterior properties as w

279 We have recreated these mutant transporters for expression in mo

280 l defects, and adding exogenous enterobactin recreates these aberrations, implicating this compound a

281 mportant step on the road towards faithfully recreating these diseases in vitro.

282 ithin brain inhibitory networks essential to recreate this complex neurodevelopmental syndrome.

283 of an analogous laboratory experiment which recreates this astrophysical system.

284 in cells that do not normally express CEM15 recreates this phenotype, but whose antiviral action is

285 Recreating this exchange in vitro, we identified the chr

286 izing antibodies (bnAbs) in infection and to recreate those events by vaccination.

287 ignaling pathway found in human samples were recreated through a series of staged transfection experi

288 Disruption of the pats1 locus was recreated through homologous recombination in several in

289 hich extent realistic GPCR structures can be recreated through modeling, carazolol was docked at two

290 actions, this methodology is often unable to recreate tissue with the hierarchical organization and v

291 Three-dimensional culture recreated tumor microenvironmental cues and led to enhan

292 To this end, we sought to genetically recreate tumorigenesis in normal human cells using genes

293 This pattern was recreated upon expression of VENUS-tagged barley (Hordeu

294 ter injury to the central nervous system, to recreate useful multidimensional control of complex devi

295 -induced calcium responses that could not be recreated using either two-dimensional technique.

296 is limited and probability models need to be recreated using limited family history as an actual vari

297 These modulations can be recreated using synthetic frequency modulated (FM) tones

298 We now have recreated VWF tubule assembly in vitro, starting with on

299 over the nasotemporal axis of the retina is recreated within the pattern of axonal terminations acro

300 ion, injured fetal tissues can be completely recreated, without fibrosis, in a process resembling reg