ライフサイエンスコーパス: tyrosine hydroxylase

1 ng somatostatin, calretinin, parvalbumin, or tyrosine hydroxylase.

2 om chromaffin cells and in the expression of tyrosine hydroxylase.

3 )/calmodulin-dependent protein kinase II and tyrosine hydroxylase.

4 d with dopamine antibodies but not with anti-tyrosine hydroxylase.

5 ing and immunohistochemistry directed toward tyrosine hydroxylase.

6 urons (DaNs) using the intracellular marker, tyrosine hydroxylase.

7 axons were stained immunohistochemically for tyrosine hydroxylase.

8 A neurons, identified by their expression of tyrosine hydroxylase.

9 and establishes the first bacterial class of tyrosine hydroxylases.

10 in knockdown did not alter the expression of tyrosine hydroxylases 1 and 2, choline acetyltransferase

11 continuously generates neurons that express tyrosine hydroxylase 2 (th2).

12 human alpha-synuclein and overexpression of tyrosine hydroxylase (a model of sporadic PD).

13 Surprisingly, these cells immunolabeled for tyrosine hydroxylase, a key component in dopamine synthe

14 The absence of coexpression of tyrosine hydroxylase, a marker for dopamine production,

15 from striatal neurons, and many also express tyrosine hydroxylase, a marker of dopaminergic neurons.

16 Human tyrosine hydroxylase activity is regulated by phosphoryl

17 cyclo-DOPA, CYP76AD6 uniquely exhibits only tyrosine hydroxylase activity.

18 ir targeting miRNAs, 145 and 133b; increased tyrosine hydroxylase and alpha-synuclein expression with

19 staining using antibodies targeted for anti-tyrosine hydroxylase and anti-calcitonin gene-related pe

20 s, including reductions in the expression of tyrosine hydroxylase and catechol-O-methyltransferase (C

21 Tyrosine hydroxylase and Cre reporter were found to be c

22 5 knock-out and control mice show comparable tyrosine hydroxylase and dopamine transporter expression

23 antia nigra pars compacta were processed for tyrosine hydroxylase and dopamine transporter immunohist

24 NA levels were decreased in the NAc, whereas tyrosine hydroxylase and dopamine transporter mRNA level

25 imbic dopaminergic system was assessed using tyrosine hydroxylase and dynorphin in situ hybridization

26 Tyrosine hydroxylase and Early Growth Response factor-1

27 ivity toward regular R-substrates (including tyrosine hydroxylase and GluR1) was significantly furthe

28 Timothy syndrome show abnormal expression of tyrosine hydroxylase and increased production of norepin

29 ic input, as indicated by abundant levels of tyrosine hydroxylase and neuropeptide Y.

30 the B2AR and catecholamine synthetic enzymes tyrosine hydroxylase and phenylethanolamine-N-methyltran

31 ne (CRH), vasoactive intestinal polypeptide, tyrosine hydroxylase, and aromatase, and labeling densit

32 tered mRNA expression of dopamine receptors, tyrosine hydroxylase, and dopamine transporter genes in

33 eptors (GalR1-R3), tryptophan hydroxylase 2, tyrosine hydroxylase, and nitric oxide synthase as well

34 Wounding downregulated B2AR, tyrosine hydroxylase, and phenylethanolamine-N-methyltra

35 rease of immunoreactivity of neuropeptide Y, tyrosine hydroxylase, and somatostatin.

36 Contents of dopamine, tyrosine hydroxylase, and the 5-HT5A serotonin receptor

37 s immunoreactive for the DA synthetic enzyme tyrosine hydroxylase; and 3) nearly all RMTg axons forme

38 Double-label IHC experiments with tyrosine hydroxylase antiserum suggested that the D(2alp

39 DNA methylation of a specific set of genes, tyrosine hydroxylase, brain-derived neurotrophic factor

40 also led to a decrease in protein levels of tyrosine hydroxylase, but not of tryptophan hydroxylase.

41 compartment as identified by costaining with tyrosine hydroxylase, but not outside these clusters.

42 We find that transgenes under control of the tyrosine hydroxylase, but not the dopamine transporter,

43 one opsin, as well as other retinal markers (tyrosine hydroxylase, calbindin, PKCalpha and Brna3), in

44 Numbers of tyrosine hydroxylase-, calbindin-, and calretinin-expres

45 Efferent nerve fibers were predominant (tyrosine hydroxylase/calcitonin gene-related peptide rat

46 urons that exhibited dual immunostaining for tyrosine hydroxylase (catecholaminergic neurons) and c-F

47 anges were associated with a greater loss of tyrosine hydroxylase cell content and intense neuroinfla

48 ucted for simultaneous detection of NOS with tyrosine hydroxylase, choline acetyltransferase, calbind

49 The putative tyrosine hydroxylase coded by orf13 of the anthramycin b

50 ns were identified as DA neurons (defined by tyrosine hydroxylase colocalization).

51 ons, implying cholinergic regulation; and by tyrosine hydroxylase-containing axons, implying adrenerg

52 In mice expressing ChR2 in tyrosine hydroxylase-containing neurons, optical activat

53 g Kluver-Barrera (myelin and cell bodies) or tyrosine hydroxylase (dopaminergic neurons) immunohistoc

54 We use GAL4;UAS-mediated rescue of tyrosine hydroxylase (DTH) mutant (ple) flies to study t

55 ation, whereas mutations decreasing VMAT and tyrosine hydroxylase exacerbated toxicity.

56 These results are consistent with tyrosine hydroxylase existing in two different conformat

57 decreased DA re-uptake and resulted in more tyrosine hydroxylase expressing neurons in the SN than i

58 Whole-cell recordings were obtained from tyrosine hydroxylase-expressing (TH(+)) neurons in stria

59 loss of the E3-ubiquitin ligase, UBE3A, from tyrosine hydroxylase-expressing neurons impairs mesoaccu

60 ly thought to originate exclusively from the tyrosine-hydroxylase-expressing (TH(+)) neurons in the v

61 dopamine levels or dopamine transporter and tyrosine hydroxylase expression after lesioning with MPT

62 e, release, D2 autoreceptor sensitivity, and tyrosine hydroxylase expression and activity as mechanis

63 AT) undergo alternative activation to induce tyrosine hydroxylase expression and catecholamine produc

64 as: an increase in LC bursting activity; in tyrosine hydroxylase expression and that of the noradren

65 n, gene expression analysis revealed reduced tyrosine hydroxylase expression and the regulation of ge

66 tive turnover throughout life and regulating tyrosine hydroxylase expression in an activity-dependent

67 pancreas, GLUT2 expression in the liver, and tyrosine hydroxylase expression in dopaminergic neurons.

68 Additionally, we found no difference in tyrosine hydroxylase expression in the substantia nigra

69 brain cortex neurotransmitter synthesis and tyrosine hydroxylase expression on intracellular ascorba

70 nts but not adults, there was an increase in tyrosine hydroxylase expression that was selective to th

71 macrine cells (brain nitric oxide synthetase/tyrosine hydroxylase expression) and ganglion cell axons

72 ling attenuated the stress-induced change in tyrosine hydroxylase expression.

73 (CT-alpha-syn) in axons, rescued the loss of tyrosine hydroxylase fibers in striatum, and improved mo

74 PKA and PKC phosphorylate and activate tyrosine hydroxylase, further increasing dopamine synthe

75 Regulation of tyrosine hydroxylase gene (Th) transcription is critical

76 Overall, the putative function of Orf13 as a tyrosine hydroxylase has been confirmed and establishes

77 essing neurons almost invariably stained for tyrosine hydroxylase, identifying them as dopaminergic.

78 ditory end organ, the saccule, combined with tyrosine hydroxylase immunofluorescence (TH-ir) revealed

79 Anterograde tracing combined with tyrosine hydroxylase immunohistochemistry demonstrates A

80 f putative dopaminergic cells and fibers (by tyrosine hydroxylase immunohistochemistry) and dopamine

81 tracer injections, both in combination with tyrosine hydroxylase immunohistochemistry, to characteri

82 ergic neurons was quantitatively assessed by tyrosine hydroxylase immunohistochemistry.

83 Tyrosine hydroxylase-immunolabeled (sympathetic) nerve t

84 nt did not alter Fos-immunoreactivity within tyrosine hydroxylase-immunolabeled neurons of VTA, but d

85 Dopamine- and tyrosine hydroxylase-immunopositive cells (TH cells) mod

86 easuring striatal dopamine levels, total and tyrosine hydroxylase immunoreactive neuron numbers and B

87 allopregnanolone promotes the restoration of tyrosine hydroxylase immunoreactive neurons and total ce

88 O-treated rats had increased preservation of tyrosine hydroxylase immunoreactive neurons in the subst

89 mid-forebrain bundle increased the number of tyrosine hydroxylase immunoreactive neurons in the subst

90 with melanin concentrating hormone (MCH) and tyrosine hydroxylase immunoreactive neurons of the hypot

91 mmunoreactive bipolar cells (one likely also tyrosine hydroxylase immunoreactive) that bore ciliated

92 mmunohistochemistry revealed that almost all tyrosine hydroxylase-immunoreactive (TH-ir) axons in the

93 eatment resulted in a significant sparing of tyrosine hydroxylase-immunoreactive (THir) neurons in th

94 is possibility, we quantified the density of tyrosine hydroxylase-immunoreactive axons as a measure o

95 Tyrosine hydroxylase-immunoreactive fibers as well as D(

96 More tyrosine hydroxylase-immunoreactive neurons and signific

97 ates of the number of melanin-containing and tyrosine hydroxylase-immunoreactive neurons in the subst

98 Lower density of tyrosine hydroxylase-immunoreactive neurons in the ventr

99 noreactive plexus and an apparently separate tyrosine hydroxylase-immunoreactive plexus.

100 d the innervation patterns of both 5-HT- and tyrosine hydroxylase-immunoreactive processes relative t

101 ad1b and gad2 expression in combination with tyrosine hydroxylase immunoreactivity in 4-day-old larva

102 Another finding was a loss of tyrosine hydroxylase immunoreactivity in gut neurons wit

103 Tyrosine hydroxylase immunoreactivity was evident in sev

104 ity measurements of dopamine transporter and tyrosine hydroxylase immunoreactivity, which were all si

105 striatal dopamine, and stereologic counts of tyrosine hydroxylase-immunostained neurons in substantia

106 (Nacc) shell, accompanied by a reduction of tyrosine hydroxylase immunostaining and postsynaptic den

107 n using virally mediated RNA interference of tyrosine hydroxylase impaired temporal control, and seco

108 rons in the sympathetic ganglia, increase in tyrosine hydroxylase in both nerve terminals in the SAT

109 The absence of tyrosine hydroxylase in GABAergic nerve terminals in the

110 a and astrocytes and decreased expression of tyrosine hydroxylase in periglomerular cells, vesicular

111 -mouse IgG1(a) autoantibody colocalized with tyrosine hydroxylase in the basal ganglia within dopamin

112 al for dephosphorylation and inactivation of tyrosine hydroxylase in vitro and in PC12 cells.

113 erations in dopaminergic phenotypic markers (tyrosine hydroxylase) in the early stages of Parkinson's

114 nsity of sensory (CGRP) but not sympathetic (tyrosine hydroxylase) innervation for Old versus Young M

115 catenin in the midline progenitors using the tyrosine hydroxylase-internal ribosomal entry site-Cre (

116 dependent on thalamic activation of striatal tyrosine hydroxylase interneurons (THINs).

117 rgic centres of Insm1 mutants, expression of tyrosine hydroxylase is delayed in the locus coeruleus a

118 rate-limiting enzyme for dopamine synthesis, tyrosine hydroxylase, is specifically disrupted in the r

119 comprising the first 50 amino acids of human tyrosine hydroxylase, isoform 1 (hTH1), that contain the

120 In mice after tMCAO, tyrosine hydroxylase levels in sympathetic fibers and bo

121 In contrast, expression of tyrosine hydroxylase mRNA, the rate-limiting enzyme in c

122 onal protein C/D, choline acetyltransferase, tyrosine hydroxylase, neuronal nitric oxide synthase, an

123 it for both at embryonic day [E]12.5-E13.5), tyrosine hydroxylase neurons (E15.5), nitric oxide synth

124 Survival of tyrosine hydroxylase neurons in the substantia nigra was

125 s localized to neurons in the VTA, including tyrosine hydroxylase neurons, but not astrocytes.

126 hat express channel-rhodopsin-2 (ChR2) in LC tyrosine hydroxylase neurons.

127 n C/D, as well as choline acetyltransferase, tyrosine hydroxylase, nitric oxide synthetase, and vasoa

128 iminished, consistent with the dependence of tyrosine hydroxylase on BH4.

129 aSWNTs attenuated METH-induced increases in tyrosine hydroxylase or synaptic protein expression.

130 f D2S but not D2L prevents the inhibition of tyrosine hydroxylase phosphorylation and, thereby, of do

131 m neurons expressing Per2 and Per3 and their tyrosine hydroxylase phosphorylation is regulated in a c

132 ode the enzymes dopa decarboxylase (Ddc) and tyrosine hydroxylase (ple).

133 Mice lacking ErbB4 in tyrosine hydroxylase-positive (TH+) neurons, but not in

134 ve study to determine the plastic changes of tyrosine hydroxylase-positive (TH1(+); mainly dopaminerg

135 with allopregnanolone restored the number of tyrosine hydroxylase-positive and total cell numbers in

136 Sympathetic innervation (tyrosine hydroxylase-positive axon density) and endothel

137 esicular ACh transporter immunoreactivity in tyrosine hydroxylase-positive cardiac sympathetic fibers

138 with motor impairment, as well as postmortem tyrosine hydroxylase-positive cell counts and striatal d

139 dures demonstrated that these cells were not tyrosine hydroxylase-positive cells in the Kolliker-Fuse

140 nts, there were more melanin-containing than tyrosine hydroxylase-positive cells.

141 ositive neurons in the nigra and decrease in tyrosine hydroxylase-positive fibers and neurotransmitte

142 ned how dopamine is stored and released from tyrosine hydroxylase-positive GFP (TH(+)-GFP) mouse peri

143 Immunohistochemistry of fos in tyrosine hydroxylase-positive LC neurons following IV ve

144 The density of tyrosine hydroxylase-positive nerves in the left stellat

145 h striatal dysfunctions preceding SN loss of tyrosine hydroxylase-positive neurons and that other neu

146 ra pars compacta, there was a 50-90% loss of tyrosine hydroxylase-positive neurons from the earliest

147 rdingly, castration also induced the loss of tyrosine hydroxylase-positive neurons in the nigra and d

148 it of motor function, diminished the loss of tyrosine hydroxylase-positive neurons in the substantia

149 symptoms are associated with massive loss of tyrosine hydroxylase-positive neurons in the substantia

150 showed neuroprotective effects by preserving tyrosine hydroxylase-positive neurons in the substantia

151 striatal denervation and loss of melanin and tyrosine hydroxylase-positive neurons, is poorly underst

152 at microRNA-7 (miR-7), which is expressed in tyrosine hydroxylase-positive nigral neurons in mice and

153 /vehicle-treated animals, almost 40% loss of tyrosine hydroxylase-positive norepinephrine neurons was

154 RDN reduced tyrosine hydroxylase-positive sympathetic nerve staining

155 hysiotropic tuberoinfundibular dopaminergic (tyrosine hydroxylase-positive) neurons; however, <10% of

156 tran-labeled axons (135 of 136 sampled) were tyrosine hydroxylase-positive.

157 nced green fluorescent protein driven by the tyrosine hydroxylase promoter (TH-EGFP).

158 red fluorescent protein under control of the tyrosine hydroxylase promoter and loaded with the calciu

159 ats with loxP-flanked (floxed) alleles and a tyrosine hydroxylase promoter-driven cre allele and demo

160 tional activity, as measured by induction of tyrosine hydroxylase promoter-luciferase activity, compa

161 s elicits a non-cell-autonomous reduction of tyrosine hydroxylase protein level in the axonal project

162 n measured immunolabeling for phosphorylated tyrosine hydroxylase (pTH-ir), the rate-limiting enzyme

163 deletion led to decreases in phosphorylated tyrosine hydroxylase (pTH-Ser40) levels in the VTA and d

164 GABA neurons were not numerous, and most non-tyrosine hydroxylase/retrogradely labeled cells lacked G

165 stochemistry of the sympathetic nerve marker tyrosine hydroxylase revealed a progressive loss of adre

166 n sections in this same plane is stained for tyrosine hydroxylase, revealing the distribution of cate

167 Tyrosine hydroxylase score, which assesses functional ne

168 t with 6-OHDA and brains were stained with a tyrosine hydroxylase-silver nucleolar (TH-AgNOR) stain.

169 ff and was accompanied by a higher number of tyrosine hydroxylase(+) SN neurons (increase of approxim

170 neuronal stress indicated by hypertrophy of tyrosine hydroxylase stained cell bodies.

171 ected by a reduction of average cell size of tyrosine hydroxylase stained neurons.

172 dopamine measurements and unbiased counts of tyrosine hydroxylase-stained nigral cells.

173 There was no significant difference in tyrosine hydroxylase staining between control subjects a

174 ortem study, a semi-quantitative analysis of tyrosine hydroxylase staining was conducted in nigral do

175 In the post-mortem study we found that tyrosine hydroxylase staining was significantly increase

176 me of these additional fibers also expressed tyrosine hydroxylase, suggesting a sympathetic origin.

177 well as with the dopamine synthesis enzymes tyrosine hydroxylase (TH) and aromatic amino acid decarb

178 In this work, we evaluated whether tyrosine hydroxylase (TH) and cytochrome P450s (CYPs) ca

179 The full length cDNA sequences of tyrosine hydroxylase (TH) and dopa decarboxylase (DDC),

180 nstrate that Hand1 is dispensable for normal tyrosine hydroxylase (TH) and dopamine beta-hydroxylase

181 Tyrosine hydroxylase (TH) and dopamine beta-hydroxylase

182 europathy was studied by staining femurs for tyrosine hydroxylase (TH) and neurofilament 200 (NF-200)

183 tiation into dopaminergic neurons expressing tyrosine hydroxylase (TH) and nuclear receptor related-1

184 ly it also greatly reduced the expression of tyrosine hydroxylase (Th) and other markers of the dopam

185 Expression of the genes Tyrosine Hydroxylase (Th) and Phenylethanolamine N-methy

186 substantia nigra that expressed both FG and tyrosine hydroxylase (TH) and striatal terminals express

187 opamine beta-hydroxylase; these neurons lack tyrosine hydroxylase (TH) and thus are not catecholamine

188 thetic enzymes of DA and 5-HT, respectively, tyrosine hydroxylase (TH) and tryptophan hydroxylase (TP

189 ted to express the neuronal markers Tuj1 and tyrosine hydroxylase (TH) at E10.5, they exited the cell

190 Tyrosine hydroxylase (TH) catalyzes the conversion of l-

191 Tyrosine hydroxylase (TH) catalyzes the rate-limiting st

192 There was a reduction in tyrosine hydroxylase (TH) density in the striatum in the

193 et of this diverse cell population expresses tyrosine hydroxylase (TH) during postnatal rat developme

194 lacing test, and a 272% increase in striatal tyrosine hydroxylase (TH) enzyme activity at 3 weeks aft

195 were euthanized for measurement of striatal tyrosine hydroxylase (TH) enzyme activity.

196 ation of the flight circuit in pupae reduces Tyrosine Hydroxylase (TH) expression in the PAM neurons

197 PAC) and homovanillic acid (HVA)] levels and tyrosine hydroxylase (TH) expression in the striatum.

198 Neither a knockdown of tyrosine hydroxylase (TH) expression in the VTA by THsiR

199 d dendrite degeneration, progressive loss of tyrosine hydroxylase (TH) expression, and enlarged mitoc

200 O1 directly targets and negatively regulates tyrosine hydroxylase (TH) expression, the rate-limiting

201 Also, REV-ERBalpha repressed tyrosine hydroxylase (TH) gene transcription via competi

202 ergic interneurons that express the gene for tyrosine hydroxylase (TH) have been identified previousl

203 grity by measuring fiber length density with tyrosine hydroxylase (TH) immunohistology and dopamine t

204 In this study we used Nissl staining and tyrosine hydroxylase (TH) immunoreactivity to compare th

205 neurons were dopaminergic (DA), revealed by tyrosine hydroxylase (TH) immunoreactivity.

206 study, we analyzed the activity of striatal tyrosine hydroxylase (TH) in rats at 1 day, 1 week, and

207 are fewer dopaminergic neurons labeled with tyrosine hydroxylase (TH) in the male AVPV than the fema

208 tegmental area (VTA) dopaminergic activity, tyrosine hydroxylase (TH) levels and dopamine synthesis.

209 luciferase reporter gene into the endogenous tyrosine hydroxylase (TH) locus enables rapid and easy q

210 the number of neurons expressing the enzyme tyrosine hydroxylase (TH) near the injected site.

211 ns were significantly reduced by 29% and the tyrosine hydroxylase (TH) negative neurons unaffected af

212 Here we introduce an unexpected neuron, the tyrosine hydroxylase (TH) neuron of the arcuate nucleus

213 whether hypothalamic arcuate (ARC) dopamine/tyrosine hydroxylase (TH) neurons interact with other AR

214 We find that >90% of VTA tyrosine hydroxylase (TH) neurons projecting to the LHb

215 PPG(+) neurons express tyrosine hydroxylase (TH) only in the A1 region of the V

216 neuromelanin pigment or immunolabeling with tyrosine hydroxylase (TH) or calbindin.

217 techolaminergic fibers with somatostatin and tyrosine hydroxylase (TH) or dopamine beta-hydroxylase (

218 PD models when there has been a decrease in tyrosine hydroxylase (TH) positive cells.

219 urons after 25 days of differentiation ( 40% tyrosine hydroxylase (TH) positive, maturing into 25% ce

220 te that VTA GABAergic neurons that coexpress tyrosine hydroxylase (TH) projecting to lateral habenula

221 nced green fluorescent protein driven by the tyrosine hydroxylase (TH) promoter (TH-EGFP) to identify

222 ng 6.3 kb of upstream sequences from the rat tyrosine hydroxylase (TH) promoter to a NFH promoter, an

223 ollowed by an upstream enhancer from the rat tyrosine hydroxylase (TH) promoter, to a neurofilament h

224 ine that expresses eGFP under control of the tyrosine hydroxylase (TH) promoter, we found that mu opi

225 The tyrosine hydroxylase (TH) promoter-driven TH-MYCN transg

226 (3-NT), an indirect index of NO production, tyrosine hydroxylase (TH) protein levels (dopamine termi

227 irment of mitochondrial function and loss of tyrosine hydroxylase (TH) protein, indicative of dopamin

228 rograde tracing and immunohistochemistry for tyrosine hydroxylase (TH) to identify bulbospinal catech

229 is a bona fide coactivator and stimulator of tyrosine hydroxylase (TH) transcription in neuronal cell

230 In contrast, expression of tyrosine hydroxylase (TH) was reduced in the DS, but not

231 leucoagglutinin (PHA-L) injections, whereas tyrosine hydroxylase (TH) was used as a marker for DA ax

232 opeptide Y (NPY)(+), parvalbumin (PV)(+) and tyrosine hydroxylase (TH)(+), we further elucidate this

233 e Y (NPY)(+), proopiomelanocortin (POMC)(+), tyrosine hydroxylase (TH)(+)] and glia (tanycytes).

234 abeling and immunohistochemical detection of tyrosine hydroxylase (TH), a DA marker.

235 (IL)-4 stimulation induces the expression of tyrosine hydroxylase (TH), a key enzyme in the catechola

236 luorescent protein (GFP) and the promoter of tyrosine hydroxylase (TH), a key synthetic enzyme for ca

237 tochemistry to detect the phosphorylation of tyrosine hydroxylase (TH), a rate-limiting enzyme in the

238 RTqPCR for paired-like homeobox 2b (PHOX2B), tyrosine hydroxylase (TH), and doublecortin (DCX) mRNA i

239 munolabeling with antibodies against VGluT2, tyrosine hydroxylase (TH), and PHA-L.

240 th that of choline acetyltransferase (ChAT), tyrosine hydroxylase (TH), and serotonin (5HT) by double

241 esicular acetylcholine transporter [VAChT]), tyrosine hydroxylase (TH), and serotonin (5HT) to identi

242 d from tyrosine by the rate-limiting enzyme, tyrosine hydroxylase (TH), and tyrosine is catabolized b

243 besides neuroprotection, BRF110 up-regulates tyrosine hydroxylase (TH), aromatic l-amino acid decarbo

244 n interact with tyrosinase (TYR) and inhibit tyrosine hydroxylase (TH), both of which are enzymes inv

245 inal whole mounts stained with antibodies to tyrosine hydroxylase (TH), DA cells gave rise to varicos

246 her vector decreased expression of rat SNCA, tyrosine hydroxylase (TH), dopamine transporter (DAT) or

247 n blot analysis to compare protein levels of tyrosine hydroxylase (TH), glutamate decarboxylase (GAD6

248 projections labeled with antibodies against tyrosine hydroxylase (TH), melanin-concentrating hormone

249 Immunostaining for tyrosine hydroxylase (TH), sodium channels (Nav ) and an

250 pha), specific to pain-sensing C-fibers, and tyrosine hydroxylase (Th), specific to low-threshold mec

251 immunohistochemical techniques for detecting tyrosine hydroxylase (TH), the initial rate-limiting enz

252 a-Syn binding inhibits the activity of tyrosine hydroxylase (TH), the rate-limiting enzyme in c

253 In contrast, myeloid-specific deletion of tyrosine hydroxylase (TH), the rate-limiting enzyme in c

254 elanization and reduced immunoreactivity for tyrosine hydroxylase (TH), the rate-limiting enzyme in d

255 protein 1 (MTA1) is an upstream modulator of tyrosine hydroxylase (TH), the rate-limiting enzyme in d

256 used immunohistochemical methods to localize tyrosine hydroxylase (TH), the rate-limiting enzyme in t

257 dopaminergic, as judged by the expression of tyrosine hydroxylase (TH), the rate-limiting enzyme of d

258 eased expression of DA neuron-enriched genes tyrosine hydroxylase (TH), vesicular monoamine transport

259 tivate expression of neuronal genes, such as tyrosine hydroxylase (TH), which is the rate-limiting en

260 ein or mCherry was injected into the RVLM of tyrosine hydroxylase (TH)-Cre rats.

261 ypic lamina-specific neurite arborization of tyrosine hydroxylase (TH)-expressing dopaminergic amacri

262 n slices from neonatal (postnatal days 6-10) tyrosine hydroxylase (TH)-GFP transgenic mice, was about

263 -immunoreactive(ir) axonal varicosities were tyrosine hydroxylase (TH)-ir and the same proportion wer

264 iation with GAD65/67-immunoreactive (ir) and tyrosine hydroxylase (TH)-ir neurons.

265 t are further divided into two subtypes: (1) tyrosine hydroxylase (TH)-positive C-LTMRs that form the

266 a3 and -beta5i subunits are colocalized with tyrosine hydroxylase (TH)-positive cells in the SN of co

267 he diagnosis of PD and demonstrated >300,000 tyrosine hydroxylase (TH)-positive grafted cells per sid

268 in a significant reduction in the number of tyrosine hydroxylase (TH)-positive mDA neurons.

269 d significant protection against the loss of tyrosine hydroxylase (TH)-positive neurons of substantia

270 f the rate-limiting enzyme for CA synthesis, tyrosine hydroxylase (TH).

271 tified following injury using an antibody to tyrosine hydroxylase (TH).

272 of the rate-limiting enzyme in DA synthesis, tyrosine hydroxylase (TH).

273 rate-limiting enzyme for dopamine synthesis, tyrosine hydroxylase (TH).

274 acid decarboxylase (GAD) 65 kDa, 67 kDa, or tyrosine hydroxylase (TH).

275 he immediate early gene c-fos and the enzyme tyrosine hydroxylase (TH).

276 Multiple tyrosine hydroxylase (Th)::Cre and choline acetyltransfe

277 ing [striatal dopamine transporter (DAT) and tyrosine hydroxylase (TH)] and alterations in the mean n

278 expression of a set of five genes [including tyrosine hydroxylase (Th)] that are necessary for differ

279 s assessed using antibodies directed against tyrosine hydroxylase (TH, DAergic marker), Iba-1 (pan-mi

280 by simultaneous detection of VGluT2 mRNA and tyrosine hydroxylase (TH; for identification of dopamine

281 protein 43 (GAP-43; sprouted nerve fibers), tyrosine hydroxylase (TH; sympathetic nerve fibers), CD3

282 esicular acetylcholine transporter [VAChT]), tyrosine hydroxylase (TH; the rate-limiting enzyme in ca

283 ubpopulation that expresses VGluT2 but lacks tyrosine hydroxylase (TH; VGluT2-only neurons), present

284 ted neurons in the NST was approximately 29% tyrosine hydroxylase [TH]-positive [i.e., presumably nor

285 es the survival of grafted dopamine neurons (tyrosine hydroxylase: TH+).

286 translation of the two non-allelic forms of tyrosine hydroxylase (th1 and th2) in zebrafish larvae.

287 urons nor alter protein expression levels of tyrosine hydroxylase, the DA transporter or vesicular mo

288 t attributable to lack of phosphorylation of tyrosine hydroxylase, the key enzyme involved in DA synt

289 sociated with reduced striatal expression of tyrosine hydroxylase, the rate-limited enzyme in DA synt

290 ion of Foxa1/2 results in down-regulation of tyrosine hydroxylase, the rate-limiting enzyme of dopami

291 oactive intestinal peptide, substance P, and tyrosine hydroxylase to quantify nerves, S100beta for gl

292 ectively inhibits phosphorylated (activated) tyrosine hydroxylase to reduce dopamine production via n

293 Tyrosine hydroxylase (TyrH) catalyzes the hydroxylation

294 Tyrosine hydroxylase (TyrH) is a pterin-dependent mononu

295 levels, sympathetic axons (immunostained for tyrosine hydroxylase) undergo robust collateral sproutin

296 ons, leading to downregulation of the enzyme tyrosine hydroxylase, which is essential for dopamine sy

297 sion also caused ectopic zonal expression of tyrosine hydroxylase, which is only expressed in adult P

298 de, vesicular acetylcholine transporter, and tyrosine hydroxylase, which selectively label spinal aff

299 Nigrally targeted expression of mutant tyrosine hydroxylase with enhanced catalytic activity in

300 te-limiting catalyzing catecholamine enzyme (tyrosine hydroxylase) within the LC and their neocortica