ライフサイエンスコーパス: a large number of genes

1 phenotypes, as well as the misregulation of a large number of genes.

2 oles in maintaining the normal expression of a large number of genes.

3 h accumulation of polymerases in the body of a large number of genes.

4 LuxR is capable of activating and repressing a large number of genes.

5 cular variations are generally correlated to a large number of genes.

6 l transduction and altered the expression of a large number of genes.

7 red transcription profiles were detected for a large number of genes.

8 ent of DNA sequence that harbors the eQTL of a large number of genes.

9 ed very similar changes in the expression of a large number of genes.

10 movement, stomata opening, and expression of a large number of genes.

11 involving changes in the expression level of a large number of genes.

12 ), induced significant expression changes in a large number of genes.

13 been found to regulate the transcription of a large number of genes.

14 is required for the normal transcription of a large number of genes.

15 as a gene required for the transcription of a large number of genes.

16 rtions correspond to antisense sequences for a large number of genes.

17 cerevisiae resulted in the identification of a large number of genes.

18 le SNPs in a large number of individuals and a large number of genes.

19 AP-1 potentially controls the expression of a large number of genes.

20 des a negative regulator of transcription of a large number of genes.

21 that the complexes both repress and activate a large number of genes.

22 strong functional similarity and co-regulate a large number of genes.

23 ancer driver genes from the regions encoding a large number of genes.

24 ew models significantly improve accuracy for a large number of genes.

25 n part and therefore regulates expression of a large number of genes.

26 may have important functions associated with a large number of genes.

27 modulating DNA methylation and expression of a large number of genes.

28 ith the potential to affect translation from a large number of genes.

29 NAs therefore have the potential to regulate a large number of genes.

30 cription factor that regulates expression of a large number of genes.

31 ssion of ATHB13 influenced the expression of a large number of genes.

32 ts incited changes in poly(A) site choice in a large number of genes.

33 tical to enabling high-resolution studies of a large number of genes.

34 an be observed in the expression profiles of a large number of genes.

35 A large number of genes affected by presence/absence and

36 ning method to mutate and then rapidly clone a large number of genes affecting vertebrate development

37 ding to the transcriptional up-regulation of a large number of genes after actin polymerization.

38 d a strikingly altered expression pattern of a large number of genes along with HTLV-I-mediated T-cel

39 added to penalized logistic modeling due to a large number of genes and a small number of subjects.

40 mily oncoproteins regulate the expression of a large number of genes and broadly stimulate elongation

41 at is associated with reduced rhythmicity of a large number of genes and disrupted nocturnal protein

42 the last Haloarchaea common ancestor gained a large number of genes and expanded its aerobic respira

43 We identified a large number of genes and gene sets that were potentia

44 wi-Snf complex is required for expression of a large number of genes and has the ability to remodel c

45 oss of either ADA2 or ADA3/NGG1 also affects a large number of genes and inhibits the rapid global in

46 Pbx1 controls chromatin accessibility to a large number of genes and is entirely conserved betwee

47 applications to the large datasets including a large number of genes and many data points.

48 or cells are the earliest events that affect a large number of genes and may predispose breast tissue

49 How the organism commands such a large number of genes and proteins for biomass degrada

50 BORIS gene leads to altered transcription of a large number of genes and the differentiation of K562

51 . the high-computational cost when analyzing a large number of genes and the inefficiency in exploiti

52 ntitative traits in plants are controlled by a large number of genes and their interaction with the e

53 we used an RNase protection assay to examine a large number of genes and we determined the level of u

54 phenomenon which is both profound (involving a large number of genes) and enigmatic.

55 rmatocytes fail to initiate transcription of a large number of genes, and arrest before entry into th

56 Most maize traits are controlled by a large number of genes, and linkage analysis of several

57 nd the transcriptome favor the expression of a large number of genes appropriate for the specific tum

58 modulation of gene expression and show that a large number of genes are aberrantly expressed in the

59 we find that early in the second trimester, a large number of genes are differentially expressed acr

60 with progenitor cells, which suggested that a large number of genes are epigenetically silenced in A

61 of human genes has led to the proposal that a large number of genes are expressed in a cell-cycle-sp

62 put experiments are being conducted in which a large number of genes are investigated in a single stu

63 A large number of genes are involved in liver regenerati

64 In Escherichia coli a large number of genes are involved in the repair of ox

65 Although a large number of genes are known to be required for neu

66 Rare damaging variants in a large number of genes are known to cause monogenic dev

67 ification error rates are obtained even when a large number of genes are pre-selected for class predi

68 This work demonstrates that a large number of genes are probably important in suscep

69 Although a large number of genes are regulated by c-MYC, only a f

70 The fact that a large number of genes are regulated by mgrA implies th

71 r to familial cases of deafness, variants in a large number of genes are responsible for moderate to

72 ne to user-introduced error, especially when a large number of genes are to be examined.

73 tatistically overrepresented within a set of a large number of genes are typically used to describe t

74 lex process that involves the interaction of a large number of genes as well as environmental factors

75 ed by the contribution of common variants in a large number of genes, as well as environmental factor

76 contribute to transcriptional activation of a large number of genes, as well as to replication, sile

77 yc transcription factor in the activation of a large number of genes associated with cell growth, inc

78 We show that a large number of genes associated with heart and liver

79 littermates, primarily in the expression of a large number of genes associated with inflammation and

80 Furthermore, a large number of genes associated with vision pathways

81 simultaneously quantitate the expression of a large number of genes at the copy number level from a

82 ading to fate divergence are associated with a large number of genes being differentially expressed b

83 ge-scale RNA sequence analysis revealed that a large number of genes belong to the sigH regulon, espe

84 Gene expression data usually contains a large number of genes, but a small number of samples.

85 A large number of genes can cause inherited retinal dege

86 However, the function of a large number of genes cannot be determined on this bas

87 Expression of a large number of genes changes in response to enrichmen

88 Intriguingly, a large number of genes coding for ionotropic and metabo

89 xhibit significant overlap, and GR regulates a large number of genes considered to be AR pathway-spec

90 During development, a large number of genes coordinately express protein iso

91 Recent genomic studies have indicated that a large number of genes could be regulated at steps afte

92 remodeling to allow sustained expression of a large number of genes critical for CD8 T cell function

93 (TPL) and its paralogs coordinately regulate a large number of genes critical to plant development an

94 d sigE) were differentially coregulated with a large number of genes depending on the type of each st

95 ed in these closely related pathogens, while a large number of genes derepressed during iron starvati

96 Molecular profiling indicated a large number of genes differentially expressed between

97 Analysis of the expression of a large number of genes displayed on a cDNA array reveal

98 ntracellular lifestyle of Salmonella demands a large number of genes distributed around the chromosom

99 SVs affected the expression of a large number of genes during fiber elongation, and a t

100 ion of stage-specific expression patterns of a large number of genes during potato somatic embryogene

101 showed changes in the expression patterns of a large number of genes during this metabolic transition

102 Sequence analysis showed that a large number of genes encode defense-related proteins,

103 s revealed that the Rrp1 regulon consists of a large number of genes encoded by the core Borrelia gen

104 'PR box') present in the promoter region of a large number of genes encoding 'pathogenesis-related'

105 ce that is present in the promoter region of a large number of genes encoding 'pathogenesis-related'

106 Many microbes have a large number of genes encoding DGCs and PDEs that are

107 Given that RpoE activated a large number of genes encoding envelope maintenance an

108 Plant genomes contain a large number of genes encoding for berberine bridge en

109 eins in mammalian cells, we demonstrate that a large number of genes encoding proteins important for

110 The identification of a large number of genes encoding proteins involved in ce

111 ated genes in switched parasites, as well as a large number of genes encoding proteins that are eithe

112 While a large number of genes encoding transcription factors (

113 GC-rich sequences found in the promoters of a large number of genes essential for mammalian cell hom

114 The identification of a large number of genes essential for serum resistance i

115 This screen also yielded a large number of genes expressed in a lamina-specific m

116 ein synthesis, targeting, and secretion, and a large number of genes for proteins with antimicrobial

117 t colonize the human gastric mucosa, possess a large number of genes for restriction-modification (R-

118 FixK2 is a regulatory protein that activates a large number of genes for the anoxic and microoxic, en

119 , has provided a method with which to sample a large number of genes from an organism.

120 n the array was detected, demonstrating that a large number of genes from distantly related species c

121 The expression of a large number of genes (>40 in some cases) is directly

122 Splice variation of a large number of genes has been implicated in various c

123 the natural variation in mRNA expression for a large number of genes has not been measured.

124 osophila melanogaster has been completed and a large number of genes have been annotated as OBPs, bas

125 Polymorphisms of a large number of genes have been associated with differ

126 In maize, a large number of genes have been identified as tassel-p

127 muscular dystrophy gene encoding dystrophin, a large number of genes have been identified that are in

128 A large number of genes have been implicated in neurodev

129 Mutations in a large number of genes have now been linked to ALS, inc

130 A large number of genes identified in this study encode

131 In the past few years, there have been a large number of genes identified that contribute to th

132 A large number of genes implicated in apoptosis and cell

133 These assays identified a large number of genes implicated in the production of

134 reproducibly show differential expression of a large number of genes important for cell cycle control

135 Although SATB1 regulates a large number of genes important for T-cell development

136 otein that can regulate the transcription of a large number of genes in a ligand-dependent fashion.

137 A recent study of a large number of genes in a panel of breast and colorec

138 scription factor that controls expression of a large number of genes in concert with the small-molecu

139 or protein (CRP) regulates the expression of a large number of genes in E. coli.

140 Usp16 binds to the promoter regions of a large number of genes in ESCs, and Usp16 binding is in

141 s sequence-binding protein, directly targets a large number of genes in germinal center B cells inclu

142 nscription factors control the expression of a large number of genes in hematopoietic cells.

143 d to the DNA-binding form and transactivated a large number of genes in lymphoid cells strictly as a

144 A large number of genes in mammalian species can undergo

145 AS6 alters the transcription of a large number of genes in MCF7 cells, but much fewer ge

146 ng the evaluation of transcript abundance of a large number of genes in parallel.

147 meric proteins involved in the activation of a large number of genes in response to inflammatory stim

148 factors may explain the abnormal splicing of a large number of genes in response to Top1cc.

149 on and acquisition of H3K4 trimethylation on a large number of genes in the absence of detectable H2B

150 method MFURE to extract candidate TFBSs from a large number of genes in the availability of microarra

151 s nucleosome positioning in the promoters of a large number of genes in the budding yeast Saccharomyc

152 tress agents by modulating the expression of a large number of genes in the Escherichia coli chromoso

153 In fact, a large number of genes in the signalling pathway of the

154 hestrates temporal and spatial expression of a large number of genes in the T-cell lineage.

155 ription factor involved in the regulation of a large number of genes including housekeeping genes as

156 regulatory genes, KinB and RpoN also control a large number of genes including those involved in carb

157 gene regulator that influences expression of a large number of genes including virulence-related gene

158 IFN) response, resulting in the synthesis of a large number of genes, including bone marrow stromal a

159 e found that ClpC affected the expression of a large number of genes, including capsule genes in Stap

160 ufficiency of CUX1 altered the expression of a large number of genes, including cell cycle regulators

161 e life span by controlling the expression of a large number of genes, including free-radical detoxify

162 tion factors and regulates the expression of a large number of genes, including genes involved in spe

163 We identified a large number of genes, including genes previously asso

164 A large number of genes, including many related to cell

165 an intermediate stage that had already lost a large number of genes, including nearly all of those i

166 messenger RNA (mRNA) alternative splicing of a large number of genes, including those involved in pla

167 which spontaneous coding mutations in any of a large number of genes increases risk by 5- to 20-fold.

168 1 (YP-STAT1), which drives the expression of a large number of genes, increases quickly but then decr

169 ls and other plants involve the induction of a large number of genes, inheritance studies in Triticea

170 Both BR and Glc coregulate a large number of genes involved in abiotic/biotic stres

171 tion factor that regulates the expression of a large number of genes involved in cellular growth, pro

172 he MtSGR function affected the expression of a large number of genes involved in different biological

173 Treatment with 6-OHDA also induced a large number of genes involved in endoplasmic reticulu

174 Intriguingly, a large number of genes involved in energy metabolism we

175 ne gene regulation that specifically removes a large number of genes involved in gametogenesis and ea

176 factor that is crucial in the regulation of a large number of genes involved in glucose, cholesterol

177 small number of heat-responsive TFs regulate a large number of genes involved in heat shock response

178 sses the transcription both of itself and of a large number of genes involved in lipid metabolism.

179 embles tumor-associated monocytes, expresses a large number of genes involved in matrix remodeling.

180 an clocks control the rhythmic expression of a large number of genes involved in metabolism and other

181 MeJA treatment induced the expression of a large number of genes involved in phenylpropanoid bios

182 distinct-UVB eliciting dramatic increases in a large number of genes involved in pigmentation as well

183 lysis revealed predominant downregulation of a large number of genes involved in proliferation and ap

184 A large number of genes involved in responses to biotic

185 Interestingly, a large number of genes involved in RNA processing showe

186 ry genes observed for a bacterial genome and a large number of genes involved in the catabolism, tran

187 MIA strongly upregulates expression of a large number of genes involved in translation initiati

188 tissues elicits a differential response from a large number of genes involved in various cellular pro

189 play key roles in development by repressing a large number of genes involved in various functions.

190 ndicate that spatially limited expression of a large number of genes is part of flower development an

191 tasets contain a small number of samples and a large number of genes, it is usually desirable to iden

192 Moreover, YAP binds directly to promoters of a large number of genes known to be important for stem c

193 using co-expression analysis have identified a large number of genes likely to be involved in seconda

194 Expression of a large number of genes linked to developmental processe

195 erate to prevent Sir-dependent repression of a large number of genes located across the genome, rathe

196 o-repressor that regulates the expression of a large number of genes, many of which are involved in d

197 ensional gene expression datasets consist of a large number of genes, many of which do not play a sig

198 genome-wide alterations in the expression of a large number of genes, many of which exhibited tempora

199 We identified a large number of genes mis-expressed in SCNT embryos.

200 e and negative transcriptional regulation of a large number of genes, most of which are not regulated

201 stingly, acidic pH induced the regulation of a large number of genes (n=597), suggesting the high sen

202 Unexpectedly, a large number of genes (nearly 30% of all genes) displa

203 /PA biosynthesis, transcription factors, and a large number of genes of unknown function.

204 Mycobacterium tuberculosis possesses a large number of genes of unknown or predicted function

205 SFPS regulates pre-mRNA splicing of a large number of genes, of which many are involved in r

206 In general, experiments that perturb a large number of genes offer more information for opero

207 A) sensors that are mainly found to regulate a large number of genes/operons in bacteria.

208 nerally struggled on simulated datasets with a large number of genes or implanted biclusters.

209 e is not random,it is rather surprising that a large number of genes overlap in the mammalian genomes

210 A large number of genes, particularly those involved in

211 tory response and statistically dysregulates a large number of genes, pathways and PPIs subnetworks i

212 A large number of genes previously determined to be expr

213 These results implicate a large number of genes previously unconnected to cell c

214 Gene expression microarrays revealed a large number of genes regulated by adipocyte-RARs.

215 ed with general growth arrest and stress; 4) A large number of genes regulated by S availability enco

216 were employed to quantitate mRNA levels from a large number of genes regulated by the p53 transcripti

217 nscription factors control the expression of a large number of genes regulating hematopoietic cell de

218 ofiles in rhd6, modulating the expression of a large number of genes related to cell wall composition

219 A large number of genes related to nervous system struct

220 omparative transcriptome analysis identified a large number of genes related to the vascular tissue f

221 IRF4 ChIP-chip showed that IRF4 regulated a large number of genes relevant to Th cell differentiat

222 In addition to identifying a large number of genes required for palate development,

223 The two-component system PhoP/PhoQ controls a large number of genes responsible for a variety of phy

224 The identification of a large number of genes selectively expressed by lymphat

225 in that it can generate expression data for a large number of genes simultaneously across multiple s

226 fic gene-expression profiling and identified a large number of genes specifically expressed in all cl

227 anscriptional states in pluripotent cells at a large number of genes subject to dynamic regulation du

228 acetylation and regulates the expression of a large number of genes, suggesting that MCRS2 could als

229 g an unbiased Oct1 target screen we identify a large number of genes targeted by Oct1 specifically un

230 Genetic studies have identified a large number of genes that affect various aspects of p

231 responds to multiple stresses and activates a large number of genes that allow bacteria to adapt to

232 Phytopathogenic bacteria possess a large number of genes that allow them to grow and caus

233 These data identified a large number of genes that are differentially expresse

234 iling in Caenorhabditis elegans has revealed a large number of genes that are expressed in the fully

235 Development of the mammalian face requires a large number of genes that are expressed with spatio-t

236 Using microarrays, we identified a large number of genes that are regulated by the system

237 d type comparisons, we were able to identify a large number of genes that are, within flowers, predic

238 nules requires the coordinated regulation of a large number of genes that comprise the constituent pr

239 factor that is involved in the regulation of a large number of genes that control various aspects of

240 Bioinformatic analysis identified a large number of genes that could be regulated by one o

241 from synchronized transformed cells reveals a large number of genes that cycle exclusively in primar

242 PhoP regulates expression of a large number of genes that differ both in their ancest

243 Thus, LPS acts to modulate the expression of a large number of genes that favor apoptosis of fibrobla

244 ly, studies of S. cerevisiae have identified a large number of genes that function in metal ion trans

245 ility of c-Myc to activate the expression of a large number of genes that promote rapid proliferation

246 Genomic association studies have implicated a large number of genes that regulate neuromodulation an

247 A large number of genes that were differentially express

248 This approach found a large number of genes that were not previously thought

249 hat responded in a lexA-dependent manner and a large number of genes that were upregulated in a lexA-

250 v can model the expression co-variability of a large number of genes, thereby outperforming state-of-

251 ven a small number of biological samples yet a large number of genes, this problem suffers from the d

252 ansduction pathway that alters expression of a large number of genes to induce these responses.

253 r signaling is the coordinated regulation of a large number of genes to optimize plant growth and dev

254 ccurred that was associated with transfer of a large number of genes to the nucleus.

255 nished the transcriptional responsiveness of a large number of genes to two distinct extracellular st

256 YjiE regulates a large number of genes upon hypochlorite stress.

257 in dynamically regulating the expression of a large number of genes upon temperature shifts.

258 hich directly integrates multi-omics data of a large number of genes using the fully connected dense

259 A large number of genes was misregulated in plants lacki

260 To validate this signature for a large number of genes, we tested a recently developed

261 A large number of genes were found to be differentially

262 A large number of genes were found to be similarly modul

263 Transcript profiling revealed that a large number of genes were up-regulated in roots by RA

264 Among them, the 33.4-kb GI12 contains a large number of genes which constitute the K (capsule)

265 ascent RNAs and RNA polymerase II binding at a large number of genes, which are positively correlated

266 ronectin resulted in increased expression of a large number of genes, which was strongly potentiated

267 , Wnt3a acutely suppresses the expression of a large number of genes while inducing osteoblast differ

268 enic capacity, but leads to dysregulation of a large number of genes whose expression is altered in o

269 We also identified a large number of genes whose expression is prolonged in

270 Our approach allowed us to identify a large number of genes whose expression levels likely e

271 costs; and additionally, there usually exist a large number of genes whose methylation level cannot b

272 A large number of genes whose mRNA levels are modulated

273 RNA sequence analyses of rrc1-3 identified a large number of genes whose pre-mRNA splicing is alter

274 We have identified a large number of genes whose transcription is influence

275 We identified a large number of genes with altered expression in infec

276 Identification of a large number of genes with cancer-specific methylation

277 s sites with distinct features and regulates a large number of genes with cooperative function in reg

278 q analysis of PHAROH knockouts revealed that a large number of genes with decreased expression contai

279 tree for a large group of species containing a large number of genes with long nucleotides sequences.

280 translation toolbox allows the expression of a large number of genes with multiple transcription fact

281 e course of genomic events that delete TSGs, a large number of genes with no apparent direct role in

282 While both groups share a large number of genes with other environmental Deltapr

283 enetic mosaic of chlamydial genes, including a large number of genes with phylogenetic origins from e

284 A large number of genes, with wide ranging functions, ar