ライフサイエンスコーパス: be best known for

1 Although Ntn1 is best known for acting as an axon guidance cue through

2 Adenosine deaminases acting on RNA (ADARs) are best known for altering the coding sequences of mRNA

3 Although the basal forebrain is best known for, and often equated with, acetylcholine

4 RF is best known for antigenic variation caused by the sequ

5 quency bands, from 20-40 THz and 60-100 THz, are best known for applications in thermography.

6 Tim-3 is a transmembrane protein that is best known for being highly expressed on terminally e

7 Serum amyloid A (SAA) is best known for being the main component of amyloid in

8 ethylglutaryl coenzyme A (HMG-CoA) reductase is best known for catalysing a rate-limiting step in cho

9 ases are structurally conserved enzymes that are best known for catalyzing the production of the calc

10 of the total protein in these cells, but it is best known for containing the 2 prototypic Pleckstrin

11 e with no lysine (K) (WNK) family of enzymes is best known for control of blood pressure through regu

12 AID/APOBEC family enzymes are best known for deaminating cytosine bases to uracil

13 Deadenylases are best known for degrading the poly(A) tail during mRN

14 ted decay (NMD) is an important process that is best known for degrading transcripts that contain pre

15 ZEB1 is best known for driving an epithelial-to-mesenchymal t

16 quired in response to replication stress and is best known for ensuring the fidelity of homologous re

17 The SMC family member condensin is best known for establishing long-range chromatin inte

18 Augustus Jacob Lockhart Clarke (1817-80) is best known for his descriptions of spinal cord anatom

19 Although he is best known for his research and his ideas, he was a g

20 This issue is honoring Donald Leung, who is best known for his work in atopic dermatitis (AD), al

21 The nucleolus is best known for housing the highly ordered assembly li

22 Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-kapp

23 RNA-binding proteins of the ZFP36 family are best known for inhibiting the expression of cytokine

24 L3) was of little interest to immunologists, being best known for its role in regulating circadian rh

25 DNA polymerase eta (pol eta) is best known for its ability to bypass UV-induced thymi

26 a component of the Wnt signaling pathway and is best known for its ability to downregulate beta-caten

27 NLRP3 is best known for its ability to form inflammasomes and

28 E7 is best known for its ability to inactivate pRb, the pro

29 Although E7 protein is best known for its ability to inactivate the retinobl

30 E6 is best known for its ability to inactivate the tumor su

31 Cofilin is best known for its ability to sever actin filaments a

32 In eukaryotes, carnitine is best known for its ability to shuttle esterified fatt

33 Whereas it is best known for its ability to suppress immune respons

34 In contrast, CFTR is best known for its activity as an ATP-dependent chlor

35 ng the most common neurological diseases and is best known for its adverse effects on brain regions t

36 The CP1 domain is best known for its amino acid editing activity.

37 Protein S is best known for its anti-thrombotic activity, serving

38 ream effector of the PI 3-kinase pathway and is best known for its antiapoptotic effects [2,3] and th

39 n is a densely charged polysaccharide, which is best known for its anticoagulant activity, although i

40 The prion protein (PrP) is best known for its association with prion diseases.

41 While UPF1 is best known for its basal cytoprotective role in degra

42 is a member of the molybdoenzyme family and is best known for its catalytic role in purine degradati

43 Although it is best known for its cholinergic neurons, the BF is in

44 The BAFF-APRIL system is best known for its control of B cell homeostasis, and

45 m(6)A modification is best known for its critical role in controlling multi

46 The IL-4/IL-13 axis is best known for its critical role in T helper 2 (Th2)

47 Adenomatous polyposis coli (APC) is best known for its crucial role in colorectal cancer

48 The ventral tegmental area (VTA) is best known for its dopamine neurons, some of which pr

49 Although erythropoietin (Epo) is best known for its effects on erythropoiesis, recent

50 ascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood vessel gr

51 The African trypanosome Trypanosoma brucei is best known for its extraordinarily sophisticated anti

52 The extracellular matrix (ECM) is best known for its function as a structural scaffold

53 Leukocyte-antigen-related-like (Lar), which is best known for its function in axonal migration and s

54 As HCF1 is best known for its function in herpes simplex virus 1

55 imer, a structure-specific DNA endonuclease, is best known for its function in the nucleotide excisio

56 APETALA2 (AP2) is best known for its function in the outer two floral w

57 BRCA1 is best known for its functions in double-strand break r

58 ap is best known for its fundamental role as a dorsal selec

59 Vitamin D is best known for its influence on skeletal health.

60 The transcription factor CREB is best known for its involvement in learning and memory

61 The PIN family of proteins is best known for its involvement in polar auxin transpo

62 Acid sphingomyelinase (ASM; E.C. 3.1.4.12) is best known for its involvement in the lysosomal stora

63 This system is best known for its lethal use in deploying effectors

64 Protein C is best known for its mild deficiency associated with ve

65 chemotherapeutic agent 5-Fluorouracil (5FU) is best known for its misincorporation into DNA and inhi

66 ESCO World Heritage site in Gibraltar, which is best known for its occupation by Neanderthals at time

67 NF-kappaB is best known for its pro-inflammatory and anti-apoptoti

68 of Mildew resistance Locus O (MLO) proteins is best known for its profound effect on the outcome of

69 cumbens, a site within the ventral striatum, is best known for its prominent role in mediating the re

70 t herpesviruses that commonly infect humans, is best known for its propensity to cause disease in imm

71 PolySia is best known for its proposed role in modulating neuron

72 While FFAR4 is best known for its protective role in obesity and dia

73 Although RpoS is best known for its regulation of genes induced in sta

74 e IRF family of transcription factors, which is best known for its regulation of interferon and inter

75 le-associated cyclin-dependent kinases, CDK5 is best known for its regulation of signaling processes

76 frequently inactivated in human cancers and is best known for its regulation of the G1/S-phase trans

77 utophagy-related 1 (Atg1) family of proteins is best known for its regulatory role in initiating auto

78 raditionally, gamma-aminobutyric acid (GABA) is best known for its role as a primary inhibitory neuro

79 Airway smooth muscle is best known for its role as an airway constrictor in d

80 Gastric inhibitory peptide (GIP) is best known for its role as an incretin hormone in con

81 Histamine is best known for its role in allergies, but it could al

82 precursor protein-cleaving enzyme 1 (BACE1) is best known for its role in Alzheimer's disease amyloi

83 is a G-protein-coupled receptor (GPCR) that is best known for its role in B cell migration and local

84 Although thrombin is best known for its role in blood coagulation, it has

85 E2F is best known for its role in cell-cycle regulation and

86 e3) is a conserved histone modification that is best known for its role in constitutive heterochromat

87 In muscle, Ca is best known for its role in contractile activation.

88 Fas ligand (FasL/CD95L) is best known for its role in delivering apoptotic signa

89 ex (PPC), part of the dorsal visual pathway, is best known for its role in encoding salient spatial i

90 Myelin is best known for its role in increasing the conduction

91 ing factor 3 (ILF3), an RNA-binding protein, is best known for its role in innate immunity by partici

92 ICAM-1 is best known for its role in mediating leukocyte adhesi

93 e yeast stress-activated protein kinase Hog1 is best known for its role in mediating the response to

94 he transcription factor Ascl1 (Mash1), which is best known for its role in neurogenesis, also functio

95 The Ionotropic Receptor (IR) superfamily is best known for its role in olfaction, but virtually n

96 contains two distinct motor polypeptides and is best known for its role in organelle transport in neu

97 The vascular endothelium is best known for its role in oxygen and nutrient delive

98 The planar cell polarity (PCP) pathway is best known for its role in polarizing epithelial cell

99 It is best known for its role in promoting type 2 immune re

100 es at the inner membrane of mitochondria and is best known for its role in regulating autophagy again

101 ghly conserved GTPase of the Rho family that is best known for its role in regulating cell polarity a

102 Cat-1 is best known for its role in regulating cell shape and

103 small GTPase Rho is a molecular switch that is best known for its role in regulating the actomyosin

104 Human DNA polymerase eta (Pol eta) is best known for its role in responding to UV irradiati

105 Ascorbate (vitamin C) is best known for its role in scurvy, in which the hydro

106 The Grb2 adaptor protein is best known for its role in signaling to the small GTP

107 The cohesin protein complex is best known for its role in sister chromatid cohesion,

108 reticulum (SR) of skeletal muscle, where it is best known for its role in store-operated Ca2+ entry

109 I (CaMKII) is a serine/threonine kinase that is best known for its role in synaptic plasticity and me

110 f activated T cells (NFAT) signaling pathway is best known for its role in T lymphocyte activation.

111 The Cas2 family of proteins is best known for its role in the bacterial and archeal

112 Piccolo, a presynaptic active zone protein, is best known for its role in the regulated assembly and

113 APETALA2 (AP2) is best known for its role in the regulation of flower m

114 JAK/STAT signaling is best known for its roles in immunity.

115 B is an N-terminal processive kinesin-2 that is best known for its roles in intracellular transport.

116 Although the small GTPase Ran is best known for its roles in nucleocytoplasmic transpo

117 a member of the Ras superfamily of GTPases, is best known for its roles in nucleocytoplasmic transpo

118 LIN28 is an RNA-binding protein that is best known for its roles in promoting pluripotency vi

119 FXII (coagulation factor XII) is best known for its roles in the contact and kallikrei

120 CX3CL1, also known as fractalkine, is best known for its signaling activity through interac

121 Ubiquitously expressed sodium pumps are best known for maintaining the ionic gradients and r

122 This is surprising, since this pathway is best known for maintaining undifferentiated germline

123 Although mammalian long non-coding (lnc)RNAs are best known for modulating transcription, their post-

124 an long intergenic noncoding RNAs (lincRNAs) are best known for modulating transcription.

125 lassified as a heterotrimeric kinesin-2 that is best known for organelle transport in neurons, yet in

126 IgE antibodies are best known for pathogenic roles in allergic diseases

127 Streptomyces are best known for producing antimicrobial secondary met

128 Although oxidative phosphorylation is best known for producing ATP, it also yields reactive

129 Caspases are best known for promoting apoptosis, yet their role i

130 They are best known for promoting neutrophil recruitment into

131 Whereas adenosine is best known for promoting anti-inflammatory activities

132 Cortical excitability is best known for promoting cell protrusion and allowing

133 Snail family transcription factors are best known for regulating epithelial-mesenchymal tra

134 In hematopoiesis, SOCS-box proteins are best known for regulating the actions of cytokines t

135 Arp2/3 is best known for regulating membrane dynamics and vesic

136 n factor Rpn4 mediates one such response and is best known for regulating the abundance of the protea

137 Dehalogenating enzymes, on the other hand, are best known for removing halogen atoms from man-made

138 a nuclear receptor/transcription factor that is best known for responding to environmental toxicant e

139 ins Par-6, Bazooka (Par-3), aPKC, and Cdc42, is best known for roles in asymmetric cell division and

140 X-rays are best known for showing where bones have fractured, b

141 PHD1 and its isoforms 2 and 3 are best known for stabilizing transcriptional regulator

142 NT Wnts are a class of secreted factors that are best known for stimulating cell division in developm

143 environments, photosymbiosis with microalgae is best known for sustaining benthic coral reef ecosyste

144 Ubiquitin is best known for targeting protein destruction by the 2

145 Arrestins are best known for terminating signaling by G protein co

146 These proteins are best known for the key roles that they play in norma

147 ULL (AP1/FUL) MADS box transcription factors are best known for the role of AP1 in Arabidopsis sepal

148 Andre Toupet is best known for the posterior fundoplication that bear

149 the class II MHC-associated invariant chain, is best known for the regulation of Ag presentation.

150 wide variety of actin filament functions and is best known for the role that it plays together with t

151 While cladribine is best known for the treatment of hairy cell leukemia a

152 Dendritic cells (DCs) are best known for their ability to activate naive T cel

153 atile, multifunctional adapter proteins that are best known for their ability to desensitize G protei

154 pDCs are best known for their ability to function as vigilant

155 Toll-like receptors (TLRs) are best known for their ability to recognize microbial

156 Annexins are soluble proteins that are best known for their ability to undergo reversible C

157 Type I interferons are best known for their antiviral role.

158 Although RNA and DNA are best known for their capacity to encode biological i

159 Monarch butterflies are best known for their continent-scale migration in No

160 They are best known for their cytotoxicity in dicot plants th

161 Mast cells (MCs), which are best known for their detrimental role in patients wi

162 Malate synthases are best known for their established role in the glyoxyl

163 2 (ULK1/2) are serine/threonine kinases that are best known for their evolutionarily conserved role i

164 Naked mole-rats (NMRs) are best known for their extreme longevity and cancer re

165 PAZ/PIWI Domain family RNA-binding proteins, are best known for their function in silencing transposo

166 r gene and its close relatives p107 and p130 are best known for their function in the control of cell

167 nopis and Asianopis, the ogre-faced spiders, are best known for their giant light-capturing posterior

168 Subsequently, pathways that are best known for their importance in regulating embryo

169 hetases (OAS) are a family of enzymes, which are best known for their important role in interferon-de

170 ing cardiac arrhythmias, pain, and seizures, are best known for their inhibitory effects on voltage-g

171 NK cells are best known for their killing of virus-infected cells

172 Both motors are best known for their participation in mitosis in oth

173 Multidrug resistance transporters (MDRs) are best known for their pathological role in neoplastic

174 c artemisinins and other bioactive peroxides are best known for their powerful antimalarial activitie

175 othelial growth factor (VEGF) family members are best known for their powerful mitotic and angiogenic

176 Macrophages are best known for their protective search and destroy f

177 eir mammalian homologs (pRB, p130, and p107) are best known for their regulation of the G1/S transiti

178 e trithorax (trxG) and Polycomb groups (PcG) are best known for their regulatory functions in Drosoph

179 lthough serine proteases and their receptors are best known for their role in blood coagulation and f

180 The MCM proteins are best known for their role in DNA replication, MCM2-7

181 t signaling pathways promote cell growth and are best known for their role in embryogenesis and cance

182 They are best known for their role in growth cone guidance, a

183 Although platelets are best known for their role in hemostasis, they are al

184 rmed in the cytoplasm of some bacteria; they are best known for their role in killing of paramecia by

185 Polycomb group (PcG) proteins are best known for their role in maintaining stable, mit

186 Telomeric proteins are best known for their role in maintenance of telomere

187 on for these specialized kidney cells, which are best known for their role in modulating acid-base ho

188 Nicotinic acetylcholine receptors (nAChR) are best known for their role in neurotransmission, but

189 Chloroplasts are best known for their role in photosynthesis, but the

190 Nebulin family members are best known for their role in regulating the stabiliz

191 ffects on almost all aspects of immunity but are best known for their role in the antiviral response.

192 Although amyloids are best known for their role in the etiology of disease

193 Voltage-gated sodium channels (VGSCs) are best known for their role in the generation and prop

194 They are best known for their role in the host defense in res

195 gnaling molecules from protein families that are best known for their roles as morphogens in specifyi

196 However, MCs are best known for their roles in allergic and inflammat

197 n beta-catenin and its fly homolog Armadillo are best known for their roles in cadherin-based cell-ce

198 The highly conserved HEATR5 proteins are best known for their roles in membrane traffic media

199 Globins are heme-containing proteins that are best known for their roles in oxygen (O(2)) transpor

200 These clusters are best known for their roles in redox proteins such as

201 ta subunits of voltage-gated Ca(2+) channels are best known for their roles in regulating surface exp

202 These proteins are best known for their roles in restraining the G1-S t

203 FGFs are best known for their roles in the early steps of pat

204 Platelets are best known for their vasoprotective responses to inj

205 Brown adipose tissue (BAT) is best known for thermogenesis.

206 Pseudocereals are best known for three crops derived from the Andes: q

207 ELFN1 is best known for trans-synaptically modulating group II

208 -stranded RNA-dependent protein kinase (PKR) is best known for triggering cell defense responses by p

209 This gene is best known for underlying the behavioral strategies o