ライフサイエンスコーパス: be down-regulated by

1 In this study, we showed that MIF expression is down-regulated by 0.75 +/- 0.10-fold of the control i

2 Finally the apoptosis inducer Trp53 was down-regulated by -1.54 fold (p<0.01), possibly asso

3 Because VEGF was down-regulated by 14.7-fold in the AP-2-transfected

4 aspase-3 precursor and 17-kDa active subunit was down-regulated by 30% and 56%, respectively, with 40

5 ncoding the cell cycle-related kinase (CCRK) was down-regulated by 50% in HF heart compared with cont

6 with normal donors, CXCR2 surface expression was down-regulated by 50% on PMN from septic patients (p

7 ically targeted by RvE1 receptor binding and was down-regulated by 65.4%.

8 They are down-regulated by a GTPase reaction in which GTP is

9 Therefore, a complete head cannot be down-regulated by a regulatory domain (without the mo

10 Expression of the human alpha subunit can be down-regulated by a splice variant of FcepsilonRIbeta

11 in A expression, but not lamin C expression, is down-regulated by a brain-specific microRNA, miR-9.

12 CD2AP.Cbl-3/c complex, suggesting that Ret9 was down-regulated by a fundamentally different mechanis

13 e genes were up-regulated by ABA at 8 h than were down-regulated by ABA.

14 Most genes (70%) were down-regulated by AbetaO treatment, suggesting a pr

15 elationship between transpiration, which can be down-regulated by abscisic acid (ABA) or by high humi

16 rmore, we discovered that the AtPGM promoter was down-regulated by abscisic acid and hydroxyurea, whe

17 togen-activated protein kinase substrate but is down-regulated by activated extracellular signal-regu

18 We previously demonstrate that OAT1 activity was down-regulated by activation of protein kinase C (PK

19 utamate dehydrogenase (GDH2) gene expression is down-regulated by ammonia under conditions where NCR

20 -1 mRNA is not decreased by miR145, while it is down-regulated by an siRNA targeting IRS-1.

21 CXCR4 mRNA and protein was down-regulated by anti-TNF-alpha antibody or by targ

22 CXCR1 expression was down-regulated by antigen stimulation both in vitro

23 , our data support the hypothesis that COX-2 is down-regulated by APC and up-regulated by nuclear bet

24 COX-2 promoter luciferase activity is down-regulated by APC in a promoter reporter construc

25 SUR1 and Kir6.2 mRNA levels are down-regulated by approximately 40-50% in response t

26 eeler mice (HRM), in which reelin expression is down-regulated by approximately 50%, showed a signifi

27 loop in prostate cancer: miR-190a expression was down-regulated by AR activation; YB-1 functions are

28 ased SLA II expression 20- to 60-fold, which was down-regulated by atorvastatin.

29 tly, several lymphoma-related ERK substrates were down-regulated by AZD6244 including MCT-1, c-Myc, B

30 at MITF is an anti-proliferation factor that is down-regulated by B-RAF signaling and that this is a

31 BCR-ABL-induced leukemias, we show that Pten is down-regulated by BCR-ABL in leukemia stem cells in C

32 red by flux through pyruvate dehydrogenase), were down-regulated by beta-lapachone treatment.

33 dicate that PKC-alpha protein expression can be down-regulated by both RNase H-dependent and -indepen

34 One protein, PotF, was found to be down-regulated by both surface-associated growth and

35 , TNFAIP2, TNFR2, ELF4, RAR gamma, and HoxA1 were down-regulated by both fusion proteins in the absen

36 nes were commonly up-regulated, and 57 genes were down-regulated by both fusion proteins suggesting t

37 Seventy four genes were up-regulated and 9 were down-regulated by both ligands.

38 g, and regulation of immune system processes were down-regulated by caffeine at 3 h.

39 ive and calcium-induced T-plastin expression was down-regulated by calcineurin inhibitors and involve

40 lated when the heart was rapidly growing and was down-regulated by caloric restriction, suggesting a

41 The activity of GFAT is down-regulated by cAMP, thus placing regulation on th

42 53, in multiple lines of human cancer cells, is down-regulated by cardiac glycoside drugs digoxin and

43 cell cycle progression, repressor potential is down-regulated by Cdk-dependent phosphorylation, resu

44 ceptor IIb, CD79b, and immunoglobulin D that are down-regulated by cell triggering and activation.

45 tes in the underexpression of molecules that are down-regulated by cell triggering and in the uniform

46 2 in an autocrine manner, and PGE2 secretion is down-regulated by cell-to-cell contact, attenuating i

47 r signal-regulated kinase, and this activity was down-regulated by chemical and biological inhibition

48 Activation of Notch2 was down-regulated by CHSY1 siRNA treatment.

49 inally, in adult males, aromatase expression is down-regulated by circulating estradiol in the hippoc

50 We demonstrate that PXY signalling is down-regulated by CLE41.

51 The -2251-bp CD-RAP promoter activity was down-regulated by co-transfection with C/EBP express

52 In most Brachypodium accessions BdODDSOC2 is down-regulated by cold, and in one of the winter acce

53 Drosophila, but unlike the fly Robos cannot be down-regulated by Commissureless.

54 , as well as other copper-deficiency markers are down-regulated by copper.

55 Rat1-ras cells than in Rat1 cells and could be down-regulated by cotransfection with a dominant nega

56 The expression level of the p(L) operon is down-regulated by Cro repressor.

57 cules expressed on NK cells or transfectants were down-regulated by cross-linking with mAbs or cell s

58 This response can be down-regulated by cryptococcal capsular polysaccharid

59 y response genes (day 14 posttreatment) that were down-regulated by CSA.

60 The protein expression of the SHH pathway was down-regulated by cyclopamine, further confirming th

61 The expression of spl was down-regulated by cytokines in INS1E cells and rat i

62 Surface CXCR4 expression was down-regulated by cytokines interleukin-4 (IL-4), IL

63 r with experiments in which AP-1 and IkappaB were down-regulated by decoy oligonucleotides and siRNA,

64 Pcsk9 expression is down-regulated by dietary cholesterol, and mutations

65 onsumer of methyl donors, and this synthesis is down-regulated by dietary/supplemental creatine.

66 for leptin, suggesting that these genes may be down-regulated by different molecular mechanisms.

67 ry molecules such as Cdc25C, Cdk1, cyclin B1 were down-regulated by DIM.

68 (TNF-alpha, IL-6, IL-12, TGF-beta, and VEGF) were down regulated by DMDD.

69 ppressor activity in HNSCC, but also that it is down-regulated by DNA promoter methylation.

70 methylation showed that LOC146880 expression was down-regulated by DNA methylation in its promoter.

71 Activity of the -88/+54 VEGF promoter was down-regulated by dominant negative Akt and up-regul

72 Furthermore, AKT-induced IGF-IR expression was down-regulated by dominant-negative Src or PTEN.

73 target genes, including the AR itself, that are down-regulated by ebp1 overexpression.

74 n, since a Bcl-2 promoter-reporter construct was down-regulated by ectopic expression of PTEN in LNCa

75 nearly all of the mitochondria-related genes were down-regulated by EE.

76 ones expressed a functional ERalpha that (a) was down-regulated by estrogen, (b) conferred estrogen-i

77 In addition, 15-PGDH levels were down-regulated by estrogen but up-regulated by the

78 ave identified a novel growth inhibitor that is down-regulated by estrogens and colocalizes with ER a

79 s, and suggest that neuronal zinc uptake may be down-regulated by excess zinc levels, but only under

80 owed that leaf hydraulic conductance (Kleaf) was down-regulated by exogenous ABA, with strong variati

81 Caspase-3, Atg5, and Beclin1 levels were down-regulated by exposing cells to their respectiv

82 ctive Pgp and that the expression of Pgp can be down-regulated by exposure to antisense oligonucleoti

83 Syk-cDNA and suppressed when Syk expression was down-regulated by expression of Syk-small interferin

84 Cell invasion, migration, and growth were down-regulated by expression of phosphatase-active

85 hat hepatocyte uptake of sulfobromophthalein was down-regulated by extracellular ATP.

86 , (System L amino acid transporter isoforms) was down-regulated by fADN infusion.

87 The SCL21 transcript itself is down-regulated by far-red light in a phytochrome A- a

88 One of the identified miRNAs, miR-190, was down-regulated by fentanyl but not by morphine.

89 he beta-catenin signaling target connexin-43 were down-regulated by FH535, and functional blockade of

90 PGC1-alpha mRNA was down-regulated by FK506.

91 posed that the levels of available MMP-2 may be down-regulated by formation of a complex with TSP-2 t

92 xtent by PKA-CQR and of the transcripts that were down-regulated by FSH, 76% were also down-regulated

93 hough both mature and nascent ErbB2 proteins are down-regulated by GA, only nascent ErbB1 is sensitiv

94 ression of HvWRKY38 in barley aleurone cells is down-regulated by GA, but up-regulated by SA and ABA.

95 e produce full neural specific activity that is down-regulated by GABA in transiently transfected neo

96 genesis (vascular endothelial growth factor) were down-regulated by gamma-tocotrienol.

97 reduced in plants in which PAL activity had been down-regulated by gene silencing.

98 These studies demonstrate that SK1 is down-regulated by genotoxic stress, and that basal SK

99 use alpha(1) integrin gene transcription can be down-regulated by glucocorticoids, the response of ce

100 149 were up-regulated and, surprisingly, 83 were down-regulated by GnRHA treatment.

101 tumor mouse model, her-2 receptor signaling was down-regulated by GnT-V knock-out, resulting in a si

102 ed that the serine/threonine kinase Aurora B is down-regulated by GpIb alpha in p53-deficient primary

103 ), encoding an antagonist of MAPK signaling, was down-regulated by GPx-1 suppression.

104 PHLPP activities in PaCa cells were down-regulated by growth factors and Nox4 reduced n

105 l regulator of cell survival and metastasis, was down-regulated by GRP-R silencing.

106 e up-regulated by >/= 2.3-fold and 266 genes were down-regulated by >/= 2-fold in response to INZ tre

107 Cellular signaling by small G-proteins is down-regulated by GTPase-activating proteins (GAPs),

108 This binding was down-regulated by GTPgammaS, but not ADPgammaS, and

109 their own, established that full-length MICA was down-regulated by HCMV, and the truncated form was n

110 to express three proteins that are known to be down-regulated by high CO(2): periplasmic and mitocho

111 the activity of nitric oxide synthase (NOS) is down-regulated by high levels of caveolin-3 in the he

112 on proteins corneodesmosin and desmoglein-1, was down-regulated by histamine.

113 cient rats, HJV shedding in these cell lines was down-regulated by holo-transferrin in a concentratio

114 es ontologically classified as developmental were down-regulated by HRG, whereas those involved in tr

115 A variety of tumor suppressor genes are down-regulated by hypermethylation during carcinogen

116 the Dicer-dependent microRNA miR-185, which is down-regulated by hypoxia.

117 Interestingly, CD40L expression is down-regulated by IFN-gamma, a type 1 cytokine with a

118 regulator (CFTR) and the NKCC1 cotransporter were down-regulated by IFN-gamma, and ST/LA pretreatment

119 the up-regulation of HIF-1alpha, HIF-2alpha was down-regulated by IH.

120 o partially rely on IL-18 and IL-2 and could be down-regulated by IL-10.

121 The RXRalpha:RARalpha complex was down-regulated by IL-1beta in HepG2 cells.

122 and ACAN expression in OA chondrocytes that was down-regulated by IL-1beta.

123 which are encoded in target genes of Stat3, were down-regulated by indirubin derivatives, followed b

124 saccharide (LPS)-induced production of IL-12 was down-regulated by infection with virulent L. pneumop

125 cells of the spleen, liver, and bone marrow is down-regulated by inflammation.

126 However, it is down-regulated by inflammatory cytokines, including t

127 turnover, and drug resistance were found to be down-regulated by inhibition of JNK2 expression, furt

128 and focal adhesion kinase (FAK) thus induced were down-regulated by inhibition of PTK7 expression usi

129 hyaluronic acid-CD44 independent manner that is down-regulated by inhibitors of the JAK/STAT pathway

130 observed when the transcript level of TcCHT5 was down-regulated by injection of TcCHT5-specific dsRNA

131 thers showed that the phosphorylation of PKR is down-regulated by insulin.

132 th SirT1, and the acetylation level of IRS-2 was down-regulated by insulin treatment.

133 y cloned GLN domain, the catalytic subdomain is down-regulated by interactions with the attenuation d

134 bound iron by hepatocytes even after TfR has been down-regulated by iron overload, and this uptake co

135 Instead, Smf3p is down-regulated by iron through a mechanism that does

136 s support the possibility that the APE1 gene is down-regulated by its own product, which would be the

137 ast, transcription factors of vascular cells are down-regulated by Jagged1 activation of the Notch1 p

138 We found that miR-539 and miR-381 are down-regulated by KIT signaling and they repressed M

139 ivated protein kinase phosphatase 1 (MKP-1), is down-regulated by KLF5 ablation.

140 an umbilical vein endothelial cell migration was down-regulated by knockdown of calponin 2 expression

141 Expression of ET-1 in DU145 CaP cells was down-regulated by knocking down endogenous beta-cat

142 rs of the GT-2 family, GmGT-2 message levels are down-regulated by light in a phytochrome-dependent m

143 all plant tissues, at a very low level, and is down-regulated by light.

144 lls, both caveolin-1 mRNA and protein levels are down-regulated by LPS.

145 reased endogenous Elk-3 mRNA levels that had been down-regulated by LPS in macrophages.

146 ich is up-regulated by LPS, whereas NAPE-PLD is down-regulated by LPS and functions as a salvage path

147 BCR signals are down-regulated by Lyn, which phosphorylates inhibito

148 apoptosis of glomerular mesangial cells can be down-regulated by M(phi) binding/ingestion of apoptot

149 -Myb binding site and the finding that c-Myb is down-regulated by mAsh1 RNA interference suggest that

150 LC expression of DO is down-regulated by maturation stimuli.

151 IL-12 production by monocytes was down-regulated by measles; the addition of recombina

152 protein 1 (GLIPR1), a novel p53 target gene, is down-regulated by methylation in prostate cancer and

153 enes was inhibited when NF-kappaB activation was down-regulated by MG132, a proteasome inhibitor, or

154 tions of the CCND1 mRNA alter its ability to be down-regulated by microRNAs in MCL.

155 Furthermore, we show that NMDAR activity is down-regulated by Mind bomb-2.

156 Among the many mRNAs that are down-regulated by miR-206, the p180 subunit of DNA p

157 g to gene ontology analysis of proteins that are down-regulated by miR-7.

158 ssor protein PDCD4 (programmed cell death 4) is down-regulated by miR-21 in breast cancer cells expre

159 nd CCNJ, a protein controlling cell mitosis, is down-regulated by miR-98 via targeting 3'-untranslate

160 tion and cellular effects, miR-21 expression was down-regulated by miR-21 inhibitor and up-regulated

161 mitochondrial permeability transition pore, was down-regulated by miR-7 through targeting 3'-untrans

162 t levels of Cu/Zn superoxide dismutase (CSD) are down-regulated by miR398.

163 In principal laminae, they are down-regulated by monocular deprivation lasting 8-21

164 the remaining livers after 50% PH, 30 miRNAs were down-regulated by more than 50%, and among them, mi

165 identified 3234 genes in cardiac grafts that were down-regulated by MR1 in naive (at least 5-fold), b

166 both mouse tissues and human HEK 293 cells; was down-regulated by MsrB1 small interfering RNA, selen

167 ression of ARHI from the paternal allele can be down-regulated by multiple mechanisms in addition to

168 m, which retards or prevents hypertrophy and is down-regulated by multiple physiological and patholog

169 affinity nerve growth factor receptor, TrkA, is down-regulated by mutant TBP in cells.

170 Importantly, SL synthesis is down-regulated by mutations in genes of the Nod LCO s

171 evels of IL-17 and IL-21 and these cytokines were down-regulated by nasal anti-CD3.

172 ces in the cytoplasmic domains, HLA-A and -B are down-regulated by Nef but HLA-C and -E are not affec

173 nstitutively are growth inhibited when Egr-1 is down-regulated by negative signals from BCR or by ant

174 c agents) and leptin secretion by adipocytes are down-regulated by neurons in coculture, effects appa

175 he promoter, RNA, and protein levels of PTEN are down-regulated by NF-kappa B.

176 mponents of the circadian central oscillator were down-regulated by NF and LPS, suggesting that a roo

177 ive role during early stages of the process, were down-regulated by NF and LPS.

178 ated during early postnatal development, and are down-regulated by NMDA receptor function.

179 Photosynthetic light harvesting can be down-regulated by nonphotochemical quenching (NPQ).

180 crosis factor and lymphotoxin beta receptors were down-regulated by NS5A.

181 ion from the p53 gene in breast cancer cells was down regulated by OM.

182 ssion of the transcriptional repressor Par-4 was down-regulated by oncogenic Ras via the Raf-MEK-ERK

183 Oskn2:beta-glucuronidase reporter expression was down-regulated by OsGRF3 and OsGRF10 in vivo, sugges

184 show that thioredoxin reductase mRNA levels are down-regulated by other sequences in the 3'-untransl

185 We report here that bio operon expression is down-regulated by overproduction of AccC, another ace

186 In cultured RPE cells, Bmp6 was down-regulated by oxidative stress and up-regulated

187 ntify a set of genes not known previously to be down-regulated by p53 and indicate that p53-induced c

188 -expressing LM cells, suggesting that it may be down-regulated by p53.

189 PIQ expression is down-regulated by p53 and DNA damage-inducing agents,

190 is a novel target of p53, and its expression is down-regulated by p53 at the promoter level.

191 er activity in a reporter gene system, which was down-regulated by p53.

192 3 kinase/Akt-mediated cell survival pathway, is down regulated by p65 but not by p50.

193 P1, cIAP2, XIAP, and A1/Bfl-1, but not iNOS, were down-regulated by pan-caspase inhibitor benzyloxyca

194 and beta-tubulins, and the androgen receptor were down-regulated by PC-SPES.

195 In summary, our data suggest that p27 is down-regulated by PDGF-BB in vascular smooth muscle c

196 es were significantly up-regulated and 1,243 were down-regulated by pegsunercept (p < 0.05).

197 levels of M3/6, a JNK-specific phosphatase, were down-regulated by PEITC via a proteasome-dependent

198 Adult prefrontal expression of miR-132 can be down-regulated by pharmacologic inhibition of NMDA re

199 tes (PKCalpha, -gamma, -delta, and -epsilon) were down-regulated by phorbol ester, cells remained res

200 mitogen-activated protein kinase activation is down-regulated by phosphatidylinositol 3-kinase throu

201 ondrial pyruvate dehydrogenase complex (PDC) is down-regulated by phosphorylation catalyzed by pyruva

202 by which protein synthesis in starved cells is down-regulated by phosphorylation of the universally

203 The actin-binding activity of fascin is down-regulated by phosphorylation, and we used two di

204 agment 1, have actin-activated MgATPase that is down-regulated by phosphorylation.

205 we have found that the ATP turnover of TrwD is down-regulated by physiological concentrations of mag

206 e that degradation from the cell surface can be down-regulated by physiologically relevant forms of s

207 deleted, 1.2-kb promoter luciferase reporter was down-regulated by PI(3) kinase inhibition.

208 cent reports demonstrate that KCNK3 activity is down-regulated by PKC; however, the mechanisms respon

209 e predominant NOS in rat small intestine and is down-regulated by platelet-activating factor (PAF).

210 se experiments revealed that vascular IGF-1R was down-regulated by platelet miR-223.

211 vating gene 2(-/-) thymocytes, GR expression is down-regulated by pre-TCR complex stimulation.

212 It was determined that the pilus locus is down-regulated by preexisting networks designed for a

213 cerol-dependent isoforms of protein kinase C were down-regulated by prolonged exposure to a phorbol e

214 ARLTS1 was down-regulated by promoter methylation in 25 percent

215 ch both the 24-hydroxylase mRNA and activity are down-regulated by PTH.

216 Human pyruvate dehydrogenase complex (PDC) is down-regulated by pyruvate dehydrogenase kinase (PDK)

217 Although cyclin D1 is down-regulated by rapamycin, the role of this down-re

218 he latter construct but not the former could be down-regulated by RasN17, supporting the importance o

219 podia and increased Rac1 activity that could be down-regulated by re-expression of syndecan-4 in the

220 ion of transfected Crh-luciferase constructs was down-regulated by REST/NRSF in a RE-1/NRSE-dependent

221 Active GTP-bound RHO proteins are down-regulated by RHO GTPase-activating proteins (RH

222 orter showed that AP1-mediated transcription is down-regulated by RhoB.

223 ed when the cellular level of beta-arrestin1 is down-regulated by RNA interference but is decreased o

224 When the expression of PNPase was down-regulated by RNAi in Chlamydomonas, very few po

225 nous genes located within 20 kb of telomeres are down-regulated by RPD3 deletion.

226 lows: Gpr30 that is stimulated and Rgs2 that is down-regulated by Runx2.

227 xane synthase and microsomal PGE(2) synthase was down-regulated by selenium.

228 e negatively regulated by Pax6, which itself is down-regulated by Shh from the ZLI in this area.

229 a is not effective when EXTL3 overexpression is down-regulated by shRNA.

230 s and human breast cancer cells in which BAK was down-regulated by shRNA were more resistant to pacli

231 Pitx2 expression is down-regulated by siRNA knockdown of Fgf9, suggesting

232 e confirmed and their nuclear translocations were down-regulated by siRNAs of TRAF6 and TAK1.

233 or-mediated signaling in cells, in which GAK is down-regulated by small hairpin RNAs.

234 otein expression and function when PPARalpha is down-regulated by small interfering RNA.

235 286), and SOX9 was reduced when beta-catenin was down-regulated by small interfering RNA (siRNA), ind

236 Furthermore, endogenous MT1-MMP was down-regulated by small interfering RNA in DU145 hum

237 ular expression in HT1080 human fibrosarcoma was down-regulated by small interfering RNA methodology,

238 reduced when expression of endogenous PrP(C) was down-regulated by small interfering RNAs.

239 Type II collagen expression, which was down-regulated by SMase treatment, was restored by t

240 It is therefore hypothesized that APC may be down-regulated by some of the venom components.

241 ppaB DNA-binding activity, and both of which were down-regulated by soy isoflavones, confirming the c

242 ve in human NSCLCs and that tumor growth can be down-regulated by specific inhibition of aromatase.

243 ral apoptotic and inflammatory pathways that are down-regulated by ST18 siRNA.

244 cancer cells in which PELP1/MNAR expression is down-regulated by stable expression of PELP1/MNAR-spe

245 vitro and less metastatic in vivo when Id-1 is down-regulated by stable transduction with antisense

246 Subcomplex levels of Aph-1 are down-regulated by stepwise addition of Psn, suggesti

247 l cells after F. nucleatum stimulation could be down-regulated by subsequent infection with P. gingiv

248 ressed in preselection DP thymocytes, but it is down-regulated by T cell receptor-mediated positive s

249 tified a large number of cellular genes that were down-regulated by TAZ.

250 evidence that cytokine-induced HMG-I(Y) can be down-regulated by TGF-beta1.

251 f miR-17/92 cluster and miR-374b/421 cluster was down-regulated by THC.

252 total lipin protein and PAP activity levels are down-regulated by the combined depletion of lipins 1

253 ly 85% of the NF-kappaB-inducible genes that are down-regulated by the R30A mutation are similarly do

254 cells, Pax3, FoxD3, Msx1 and cadherin 6B all are down-regulated by the start of migration.

255 The p53 tumour suppressor protein is down-regulated by the action of Mdm2, which targets p

256 LMP2 expression is down-regulated by the adenovirus protein E1A, which b

257 Here we report that Atgl is down-regulated by the basal transcription factor Sp1

258 ng growth factor (TGF)-beta signaling, which is down-regulated by the E3 ubiquitin ligase Smad ubiqui

259 strate that the renal D1 receptor expression is down-regulated by the extracellular cAMP-adenosine pa

260 ations indicate that the expression of FABP5 is down-regulated by the Kruppel-like factor KLF2, sugge

261 ncreased when the Bcl-2 family protein Mcl-1 is down-regulated by the Raf/vascular endothelial growth

262 Here, we show that NS is down-regulated by the tumor suppressor p14(ARF) and t

263 cription from the prpBCDE and prpR promoters was down-regulated by the addition of glucose or glycero

264 APK Erk and subsequent protein synthesis but was down-regulated by the alternate MAPK, p38.

265 This proliferative effect was down-regulated by the arginase inhibitor L-norvaline

266 EpCAM promoter luciferase activity was down-regulated by the degradation of beta-catenin or

267 GF induction of the forkhead-dependent genes was down-regulated by the NF-kappaB inhibitor, constitut

268 determined that heavy metal uptake by Smf1p was down-regulated by the product of the S. cerevisiae B

269 that of the orexigenic genes NPY and CaMKK2 was down-regulated by the respective compounds 1, 5, 6 a

270 he expression of RPTPbeta/zeta or syndecan-3 was down-regulated by the RNAi technology.

271 The expression of MUC4 was down-regulated by the stable integration of a plasmi

272 microsomal PGES1, PGES2 and cystosolic PGES) was down-regulated by the TZDs.

273 xpressions of Cyclin B1, Cyclin D1, and HIAP were down-regulated by the inhibition of NF-kappaB.

274 at the immune responses mediated by them can be down-regulated by their own inherent suppressive natu

275 We identify mRNAs that are down-regulated by these miRNAs and propose roles for

276 persists in differentiating Muller glia but is down-regulated by these cells as maturation proceeds.

277 targets of miR-21 and miR-155, respectively, were down-regulated by these miRs.

278 In contrast, the expression of TRIM59 was down-regulated by TLR3 and TLR4 ligands in both huma

279 eride transfer protein and apolipoprotein B) were down-regulated by TM in WT and even more in ATGL KO

280 enzyme required for collagen cross-linking, is down-regulated by TNF-alpha in a concentration- and t

281 Others were down-regulated by TNF inhibition and included genes

282 mone alpha-subunit (TSH alpha) gene promoter is down-regulated by TR in the presence of T(3).

283 ugh microarray analysis, Cited2 was found to be down-regulated by transforming growth factor beta1 (T

284 Expression of CLM-1 mRNA is down-regulated by treatment with receptor activator o

285 Importantly, expression of CD86 on mDCs was down-regulated by Tregs in vitro, and adoptive trans

286 ent expression in dendritic cells (DC) might be down-regulated by tumor cells.

287 s been implicated as a tumor suppressor that is down-regulated by tumor-promoting phorbol esters in b

288 As these potentiated interactions were down-regulated by two pharmacotherapies, this effec

289 rotein kinase A (PKA) inhibitor, KT5720, and was down-regulated by tyrosine kinase inhibitors and a p

290 rsFC strength in an amygdala-insula circuit was down-regulated by varenicline and nicotine in abstin

291 xpressed in vascular smooth muscle cells and is down-regulated by vascular injury.

292 VRN2, a dominant repressor of flowering that is down-regulated by vernalization.

293 d irritant dermatitis in FVB.delta(-/-) mice were down-regulated by Vgamma5(+) DETC, but not by epide

294 This pathway is down-regulated by virus- and host-encoded enzymes tha

295 downstream target genes, ind and msh, which are down-regulated by vndNK-2.

296 Under long days, VRN3 transcription is down-regulated by VRN2, a unique flowering repressor

297 P13, another member of the human MMP family, was down-regulated by wild type p53, whereas all six of

298 O, FZD1, L1CAM, MMP2, NETO2, CTGF, and EDG2, were down-regulated by wild-type but not by mutant Nm23-

299 -3-kinase signal transduction, given that it was down-regulated by Wortmanin treatment.

300 us, the activity of mZip5 does not appear to be down-regulated by zinc repletion.