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1                 Each founder cell appears to be instrumental in generating a single larval muscle wit
2 1p-dependent mitochondrial dysfunction could be instrumental in promoting acute Ca2+ dyshomeostasis.
3 generic framework proposed in this work will be instrumental in developing allosteric therapies align
4 uctural and functional abnormalities and can be instrumental in diagnosing ALVC.
5                                    They will be instrumental in discovering and characterizing their
6 iously been identified for connexins and may be instrumental in guiding and understanding novel aspec
7 orchestration of head movements, which might be instrumental in guiding animals towards spatial targe
8  versus atypical motor development will also be instrumental in teasing apart the mechanistic functio
9  reticulum (ER) stress response was shown to be instrumental in initiating apoptosis in THP-1 myeloid
10          Further studies of small SMCs could be instrumental in understanding atherosclerosis pathoge
11  of a PLD3/4-specific biochemical assay will be instrumental in understanding better both nucleases a
12 of gastric epithelial cell EGF receptors may be instrumental in regulating both proliferative and inf
13 s impact the joint angles of the elderly can be instrumental in optimizing cabinet designs for elderl
14         Thus, the evolution of resisters may be instrumental in preserving cooperative behaviour in t
15                  Biological fluid stains can be instrumental in solving crimes.
16 rial DNA variants produced by MitoScape will be instrumental in diagnosing disease in the context of
17           Sequencing herbarium specimens can be instrumental in answering ecological, evolutionary, a
18                          These results could be instrumental in defining effective interventions that
19 uld help control interpandemic influenza and be instrumental in preparing for pandemic influenza.
20 ity and generalizability of the method could be instrumental in combating future viral outbreaks.
21 ll MAP kinases by H. pylori cag+ strains may be instrumental in inducing gastroduodenal inflammation,
22 ability, the olfactory cortex might prove to be instrumental in uncovering general functional princip
23 quired susceptibility in the population will be instrumental in developing health and regulatory poli
24 molecular dynamics simulations were found to be instrumental in outlining how the employed cyclizatio
25   Biochemical and structural approaches will be instrumental in revealing how potential exosites in d
26 their synergy with classical blocker Abs may be instrumental in potentiating immunotherapy strategies
27 improving durable functional islet mass will be instrumental in facilitating islet transplantation as
28 0 and other compounds identified by HTS will be instrumental in defining Kir channel structure, physi
29 into this critical biological event but also be instrumental in advancing knowledge of brain developm
30 we believe adiabatic quantum computers might be instrumental in training machine learning models effi
31 architecture, regulation and assembly - will be instrumental in expediting natural product discovery.
32  high expression in the immature brain could be instrumental in regulating neurogenesis and cell prol
33 ward, evolutionary theoretical modeling will be instrumental in advancing new research in the field,
34                              These data will be instrumental in identifying novel early cancer biomar
35           In particular, this approach could be instrumental in validating novel MRI-based techniques
36    Further interweaving of these fields will be instrumental in extending our understanding of the la
37 2)e emission hot-spot life-cycle stages will be instrumental in identifying pathways to achieving net
38                      Molecular imaging could be instrumental in improving patient care on both fronts
39  work targeting DDR specific phenotypes will be instrumental in improving patient outcomes.
40 rmalities in mobile sensor data patterns can be instrumental in identifying potential changes in symp
41                            This finding will be instrumental in developing practical and user-friendl
42    The age pattern of under-5 mortality will be instrumental in assessing progress towards the declin
43 Here we report a novel phenomenon that could be instrumental in triggering protein aggregation in neu
44 wth factors and cytokines have been shown to be instrumental in guiding such changes in keratinocyte
45 illations are coupled and the coupling might be instrumental in aligning temporally the initiation of
46 methods used to monitor HDV viremia and will be instrumental in achieving that goal.
47 n addition, these mouse models will prove to be instrumental in addressing the role of IFs in the pro
48                         Our model would also be instrumental in assessing the transforming potential
49 populations of viable CD45R- precursors will be instrumental in characterizing the earliest B-lineage
50 localization of some of the FGFR ligands may be instrumental in controlling the spatial restriction o
51                       Upcoming evidence will be instrumental in defining the net benefit of novel dia
52 ured mammalian cells and mice are proving to be instrumental in defining the relationship between the
53 RF binding and subsequent EF-G binding could be instrumental in destabilizing the PoTC and (ii) the m
54 ect, the functionality of beta-catenin could be instrumental in determining the balance between immun
55 -evoked responses in single cells and should be instrumental in determining the factors capable of mo
56  PDZ domain-containing proteins, which could be instrumental in determining the location of interacti
57  regulatory/targeting subunits is thought to be instrumental in directing the phosphatase to specific
58 d to prolonged invasion by exotic plants may be instrumental in distinguishing the role of plant-micr
59 dab:GFP and cd45:DsRed transgenic lines will be instrumental in elucidating the immune response in th
60 ible for productive clinical infection could be instrumental in elucidating the molecular basis of HI
61 d virus and sequences evolving from it could be instrumental in elucidating the transmission of human
62 ing yeast Polo-like kinase Cdc5 was found to be instrumental in establishing the meiosis I chromosome
63 w they correlate with clinical outcomes will be instrumental in guiding the optimal use of immune rec
64 estimates of isotopic abundance patterns may be instrumental in identifying the many unknown compound
65 xt generation sequencing technologies should be instrumental in mapping the specific junctions of mos
66                 These findings will not only be instrumental in matching the various t haplotype sper
67                           These efforts will be instrumental in maximizing the functional potential o
68 riven oscillations in the resource appear to be instrumental in protecting the regulation against mut
69 everal key features of MS lesions and should be instrumental in providing the missing link to transla
70 ies to remove extra-viral DNA impurities may be instrumental in reducing the immunogenic properties o
71 etoprotein (AFP) levels during pregnancy may be instrumental in reducing the subsequent risk of breas
72 rial warning labels on tobacco packaging may be instrumental in reducing the toll of the tobacco epid
73             Thus, ROCK2 signaling appears to be instrumental in regulating the balance between proinf
74      We propose that potentiating p38K might be instrumental in restoring the mitochondrial detoxific
75                       This consistency could be instrumental in simplifying the integration of AI too
76 erturbation to the enzyme/substrate and will be instrumental in studying the assembly of large polyme
77 igh-resolution magneto-optical tweezers will be instrumental in studying the interplay between the to
78 eered mice and mouse-specific reagents, will be instrumental in studying the pathogenesis of MN and e
79 tinued characterization of UPL1 and 2 should be instrumental in understanding the functions of ubiqui
80            The proposed model is expected to be instrumental in understanding the fundamental physics
81 is murine model of type 2 AIH is expected to be instrumental in understanding the immunologic mechani
82                            Our findings will be instrumental in understanding the molecular processes
83 particular DR beta/DQ beta residues that may be instrumental in understanding the pathophysiology of
84                          These advances will be instrumental in unravelling the pathogenesis that und
85 at drive immune tolerance to allergens, will be instrumental in designing therapeutic strategies to t
86                           Such knowledge may be instrumental in transforming therapeutic paradigms.
87 l established in the physical sciences could be instrumental in achieving this goal.
88 onal activator Zelda (ZLD) has been shown to be instrumental in driving this process in Drosophila me
89 ion of critical care medicine can and should be instrumental in helping this happen.
90    In all eukaryotes, catalase is thought to be instrumental in removing this H(2)O(2).
91 applications of chemical biology, which will be instrumental in unraveling this new frontier of ubiqu
92                  Hopefully, this crisis will be instrumental in helping us define novel avenues of re
93 o the expected vast viral diversity, and may be instrumental in understanding viral evolution.
94 led NK cell-mediated injury and, thus, might be instrumental in preserving vision.
95 pport of vaccine licensure.A ZIKV CHIM could be instrumental in determining which of the many ZIKV va