ライフサイエンスコーパス: be significantly associated with

1 h 5-mug/dL higher childhood blood lead level was significantly associated with 1.19-cm2 smaller corti

2 The polygenic risk score was significantly associated with 10-year CHD incidence

3 VAT and SAT were significantly associated with 155 (101 urine) and 4

4 p = 0.0003) and rs35418153 (p = 0.0004) that are significantly associated with a mental composite sco

5 e (odds ratio [OR] = 0.72, 95% CI 0.56-0.91) is significantly associated with a 28% reduced likelihoo

6 We discovered a genomic region at 1q32 that was significantly associated with a 0.12-L decrease in t

7 h 5-mug/dL higher childhood blood lead level was significantly associated with a 2.07-point lower IQ

8 The decline in global efficiency was significantly associated with a decline in psychomot

9 replacement from 2013-2017, the BPCI model 3 was significantly associated with a decrease in mean ins

10 In the overall population, excess GWG was significantly associated with a decreased risk of pr

11 (measured using Magnetisation Transfer, MT) was significantly associated with a disinhibition phenot

12 The presence of an ophthalmologist was significantly associated with a greater proportion o

13 acebo, among women who had an intact uterus, was significantly associated with a higher breast cancer

14 Lower preoperative levator function was significantly associated with a higher frequency of

15 pecific CHCs, instead of transplant receipt, was significantly associated with a higher prevalence of

16 us poor level in both midlife and late life) was significantly associated with a lower dementia risk

17 At 12 months, BB was significantly associated with a lower incidence of m

18 Ivor Lewis TMIE was significantly associated with a lower incidence of p

19 Living surrounded by greener environments was significantly associated with a lower prevalence of

20 rming PCI, compared with not performing PCI, was significantly associated with a lower rate of MACE f

21 nd free of ASCVD at baseline, new statin use was significantly associated with a lower risk of all-ca

22 ntihypertensive agents compared with control was significantly associated with a lower risk of incide

23 re, a 1-unit increase in ESD consensus score was significantly associated with a more responsive ESD

24 ntihypertensive agents compared with control was significantly associated with a reduced risk of deme

25 Prolonged ART-treatment (>=10 years) was significantly associated with a richer gut microbiot

26 d achievement of MRD negativity in BM and PB were significantly associated with a lower CIR rate, aft

27 Along with lower T stage, MSI(+) cases were significantly associated with a reduced pCR rate (o

28 n-echo lesions (odds ratio, 1.06; P = 0.036) were significantly associated with a retrospectively mor

29 The intellectual disability gene set was significantly associated with ADHD risk in the disco

30 dence within a disadvantaged US neighborhood was significantly associated with adherence to initial d

31 ecimens showed that the expression of PIK3CG was significantly associated with advanced clinical stag

32 226 (28%) patients died and risk of death was significantly associated with advancing patient age

33 ct masking indoors; indoor social distancing was significantly associated with age, and race/ethnicit

34 Furthermore, this SNV was significantly associated with AgP in a population-ba

35 Furthermore, elevated plateletcrit was significantly associated with AIS/CES, eosinophil pe

36 Nine of these loci were significantly associated with alcohol-related cirrh

37 phase 1 validation cohort; 6 of these 9 loci were significantly associated with alcohol-related cirrh

38 Diabetic retinopathy was significantly associated with all outcomes on multiv

39 Postneonatal mortality was significantly associated with all pollutants: NO2, 1

40 In those without diabetes, PN was significantly associated with all-cause mortality (H

41 In adjusted models, PN was significantly associated with all-cause mortality (h

42 Among these CpGs, 12 CpGs were significantly associated with all-cause mortality (

43 F readmissions (HR, 2.10 [95% CI,1.17-3.76]) were significantly associated with all-cause mortality.

44 whereas involvement of thoracic lymph nodes was significantly associated with an adverse outcome (P

45 LTFU was significantly associated with an ED revisit within 4

46 Blood loss was significantly associated with an increase in operati

47 nt admission between diagnosis and treatment was significantly associated with an increase in time to

48 In this South Indian cohort, a low BMI was significantly associated with an increased risk for

49 this matched study of aging individuals, HIV was significantly associated with an increased risk of N

50 Medicaid expansion policies were significantly associated with an increase in dilate

51 Two factors were significantly associated with an increased likeliho

52 analysis showed that the following variables were significantly associated with an increased risk for

53 BRCA2 and MSH2 were significantly associated with an increased risk for

54 bumin (HR = 2.1; 95% CI = 1.5-2.9; P < 0.01) were significantly associated with an increased risk of

55 AO from the first to second blood collection were significantly associated with an increased risk of

56 ty, and increased (68)Ga-PSMA-11 uptake time were significantly associated with an overall poorer ima

57 variable logistic regression model, headache was significantly associated with any tinnitus (odds rat

58 GPS was significantly associated with AP when adjusted for d

59 , the presence of artifacts on the RNFL scan was significantly associated with artifacts on the macul

60 Serious complications were significantly associated with ASA 4/5 (OR, 3.84; 95

61 EAAs detected by OCTA in diabetic eyes are significantly associated with baseline DR severity,

62 Ct tertile was significantly associated with baseline CSF lactate (

63 ession analysis demonstrated the progression was significantly associated with baseline SVC EAA (odds

64 ntrast, the advance in autumn farming phases was significantly associated with below average summer w

65 dditionally, the GReX of KCTD12 was found to be significantly associated with beta-amyloid (p value =

66 Higher income and more education were significantly associated with better adherence (P <

67 y localized CD3+ T-cells at the tumor center were significantly associated with better disease-free s

68 In contrast to topo IIalpha, topo IIbeta was significantly associated with blast percentage in ma

69 Although a variant from 15q24.3 was found to be significantly associated with both NSCPO and NSCLP, t

70 res, and pain/discomfort at the implant site were significantly associated with both outcomes (increa

71 els showed no FSC from the 12 profiled foods were significantly associated with BP, other endogenous

72 and development effects), variations in iWUE were significantly associated with changes in c(a) and S

73 , of which hsa-miR-155-5p and hsa-miR-532-5p were significantly associated with changes in dexamethas

74 Age, SMA type, and ambulatory status were significantly associated with changes in mean HFMSE

75 out cross-validation demonstrated that these were significantly associated with children's cognitive

76 cross-validation showed that these profiles were significantly associated with children's learning a

77 howed that allele turnover of candidate SNPs was significantly associated with climate gradients.

78 ndent melanoma cohorts, NMD-escape mutations are significantly associated with clinical-benefit to ch

79 NASH and concomitant advanced fibrosis (AF) was significantly associated with clinical outcomes (haz

80 -free DNA sequencing at day 7 after infusion was significantly associated with clinical response (P =

81 Perinatal HIV infection was significantly associated with community composition

82 , or imperfect daily adherence (P = .35) but was significantly associated with completing 2 or more 2

83 Among older adults, dysanapsis was significantly associated with COPD, with lower airwa

84 % of wristbands, and 6 OPEs and 4 phthalates were significantly associated with corresponding urinary

85 Obesity (BMI > 30) was significantly associated with cortical and subcortic

86 anuloma or moderate-severe ileitis on biopsy were significantly associated with Crohn's development (

87 nhancer that is predicted to target CRKL and is significantly associated with CTD risk (GH22J020946,

88 Increased willingness was significantly associated with current employment or

89 In multivariable analysis, peak ALT was significantly associated with death or discharge to

90 ponin I >0.03 to 0.09 ng/ml; n = 455; 16.6%) were significantly associated with death (adjusted hazar

91 increased risk of EOCRC, and aspirin use to be significantly associated with decreased risk; these f

92 tion of liraglutide, a type 2 diabetes drug, is significantly associated with decreased risk of AD di

93 overweight or obese (relative to normal BMI) were significantly associated with decreased odds of EOC

94 Higher viral load was significantly associated with dengue severity; for e

95 We report 77 traits that are significantly associated with depression-PRS, in bot

96 .25) and lack of social cohesion (OR = 1.76) were significantly associated with depression in the ful

97 In the evaluation cohort, HER2DX was significantly associated with disease-free survival

98 nimal studies suggest that sleep disturbance is significantly associated with disruptions in protein

99 High SOX11 levels in breast tumours are significantly associated with distant metastasis and

100 HER2DX was significantly associated with distant metastasis-fre

101 uch as noninfective enteritis and colitis to be significantly associated with DST shifts in the Unite

102 teristics, only receiving a disability grant was significantly associated with dual non-adherence at

103 , or malignant because the malignant lesions are significantly associated with early enhancement curv

104 nonuclear cells, we identified 15 sites that were significantly associated with eGFR (false discovery

105 In multivariable analysis, severe ALI was significantly associated with elevated inflammatory

106 To identify which adducts were significantly associated with embryo malformations,

107 DED was significantly associated with female gender p = (0.0

108 Noninvasive HMV use compared with no device was significantly associated with fewer all-cause hospit

109 that a high Simpson's Dominance index (SDom) was significantly associated with fewer metastases (P =

110 The SNPs rs17111495 and rs17843626 were significantly associated with FGF23 level, with the

111 ng a radio-genomics dataset, Statistical RMS was significantly associated with FOXF2 gene by both cor

112 Diabetic retinopathy is significantly associated with future risk of CVA, MI,

113 In the LBC1936, 22 of the proteins were significantly associated with general fluid cogniti

114 othesize that healthcare market factors will be significantly associated with geographic variation in

115 effect (p = 9.4 x 10-3), whereas BP alleles were significantly associated with gestational duration

116 cations such as rejection and early glaucoma were significantly associated with graft failure.

117 iences (adjusted odds ratio range=1.04-1.18) were significantly associated with greater odds of comor

118 ited States, several types of primary cancer were significantly associated with greater risk of devel

119 eal involvement, perimeter, and circularity) were significantly associated with growth rate.

120 ) and high BMI (OR = 1.19, 95% CI 1.07-1.33) were significantly associated with having cirrhosis.

121 n who have sex with men (28.21; 5.19-153.38) were significantly associated with HBV exposure.

122 Importantly, frequencies of T(FH) cells were significantly associated with HCV RNA reduction, ex

123 Both direct and caretaker DNA repair GAs were significantly associated with high TMB (P = 0.0005

124 ), and ICU stay at transplantation (p=0.029) were significantly associated with high-grade viremia.

125 Higher comorbidity burden was significantly associated with higher adjusted risk o

126 The risk allele A in rs7175922 (CYP19A1) was significantly associated with higher levels of estra

127 neighborhood-level cardiovascular resilience was significantly associated with higher LS7 (beta=0.23

128 Higher individual psychosocial resilience was significantly associated with higher LS7 (beta=0.38

129 Emergency esophageal resection was significantly associated with higher QLQ-OG25 scores

130 nente Northern California, follow-up testing was significantly associated with higher rates of hospit

131 eatment exposure, compared with nonexposure, was significantly associated with higher risk of any men

132 esiding in a food insecure hotspot community was significantly associated with higher subsequent inci

133 level, and history of living in a rural area were significantly associated with higher adjusted odds

134 Higher AAMRs were significantly associated with higher all-cause mort

135 to control one's schedule, and work setting were significantly associated with higher OLBI scores.

136 .g., troponin I >0.09 ng/dl; n = 530; 19.4%) were significantly associated with higher risk (adjusted

137 ascular disease, diabetes, and renal disease were significantly associated with higher risk for aHF a

138 r mean QA values along the identified tracts were significantly associated with higher striatal (11)C

139 lanine, glycerol-3 phosphate, and isocitrate were significantly associated with higher T2D risk (17-4

140 As and 85/91 (93.4%) of the correlated genes were significantly associated with higher tumor-grade wh

141 spnea, hospitalization, and disease severity were significantly associated with higher VN titer.

142 ophil-to-lymphocyte ratio and platelet count were significantly associated with HPD status (P = 0.038

143 Development of nonsevere cGVHD was significantly associated with improved overall survi

144 4.21), and rheumatoid arthritis (HR = 3.30) were significantly associated with incident ERD.

145 DVs (hazard ratio, 2.45 [95% CI, 1.48-4.04]) were significantly associated with incident HF hospitali

146 For many genes, SVs are significantly associated with increased numbers or g

147 ans, we found increasing age and male sex to be significantly associated with increased risk of EOCRC

148 This variant's rare allele is significantly associated with increased BP in middle-

149 samples confirmed that high eIF4E expression was significantly associated with increased ERalpha and

150 resence of APOE epsilon4 where tau pathology was significantly associated with increased microglial c

151 rses of antibiotics (P-value > 0.05), but it was significantly associated with increased number of po

152 usting for disease risk and donor group, RIC was significantly associated with increased relapse (haz

153 Clarithromycin use was significantly associated with increased risk of CV h

154 NASH was significantly associated with increased risk of hepa

155 Severe illness was significantly associated with increased total IgA (s

156 azard of a thrombotic event (P = .4163), but were significantly associated with increased hazard of d

157 e cortex and hippocampal grey matter density were significantly associated with increased NFL concent

158 erior temporal and inferior temporal regions were significantly associated with increased odds of pro

159 o intervention (OR, 1.09; 95% CI, 1.07-1.12) were significantly associated with increased registratio

160 justed analyses, increasing age and male sex were significantly associated with increased risk of EOC

161 6 and TNF-alpha, but not IL-1RA or TGF-beta, were significantly associated with increased risk of hos

162 ients with cancer after SARS-CoV-2 infection was significantly associated with increasing age, rising

163 HCV infection was significantly associated with injection drug use (od

164 Levels of 41 metabolites were significantly associated with IS compared to NCs.

165 by the patient in the week before admission were significantly associated with isolation success (P

166 oma, eye examination and higher income level were significantly associated with knowledge of glaucoma

167 with limited-interventions orders, older age was significantly associated with less POLST-discordant

168 The PGSs for MD were significantly associated with lithium treatment res

169 onstruct outcome variables on CSF biomarkers were significantly associated with long-term cognitive d

170 etastases also had a diagnosis of ICH, which was significantly associated with longer length of stay

171 common variant rs2853669 (at position -245) was significantly associated with longer telomere length

172 prescriptions top-ranked repositioned drugs are significantly associated with lower odds of AD diagn

173 d HR 0.69, 95% CI 0.55-0.88), while ACEI/ARB was significantly associated with lower all-cause mortal

174 f US adults, a greater number of daily steps was significantly associated with lower all-cause mortal

175 er eating frequency (>=5 eating occasions/d) was significantly associated with lower BMI (-1.88; 95%

176 among women who had a previous hysterectomy, was significantly associated with lower breast cancer in

177 Deficient compared with higher vitamin B-12 was significantly associated with lower cognitive score

178 Initiation of pulmonary rehabilitation was significantly associated with lower mortality across

179 ally proxied inhibition of HMG-CoA reductase was significantly associated with lower odds of epitheli

180 Decline in FM was significantly associated with lower risk of both HF

181 Every 3 additional sessions was significantly associated with lower risk of death (H

182 Initiation within 90 days was significantly associated with lower risk of death ov

183 Furthermore, decline in WC was significantly associated with lower risk of HF with

184 In contrast, decline in WC was significantly associated with lower risk of HF with

185 Noninvasive HMV, compared with no device, was significantly associated with lower risk of hospital

186 BPAP compared with no device was significantly associated with lower risk of mortalit

187 rehabilitation within 3 months of discharge was significantly associated with lower risk of mortalit

188 Socioeconomic deprivation was significantly associated with lower uptake for the c

189 whole grains, nonjuice fruit, and vegetables were significantly associated with lower odds of prevale

190 6 months of death, treatment-limiting POLSTs were significantly associated with lower rates of ICU ad

191 CRF and weight loss over a 4-year follow-up were significantly associated with lower risk of HF (haz

192 aving Medicaid or being uninsured (P < .001) were significantly associated with LTFU.

193 7), GLS and LA reservoir strain below median were significantly associated with MACE.

194 Higher risk of both progression and death was significantly associated with male gender, worse per

195 maternal antenatal corticosteroid treatment was significantly associated with mental and behavioral

196 RP and positive pathologic lymph node status were significantly associated with metastases outside th

197 The top variant at this locus (rs2571244) was significantly associated with methylation in prefron

198 to 5.63]; p(trend) = 0.019), whereas sdLDL-C was significantly associated with MI alone (HR(Q4): 3.71

199 TRL-C was significantly associated with MI and PAD (MI hazard

200 Liver injury during COVID-19 was significantly associated with mortality (P = 0.007;

201 In contrast, stress hyperglycemia ratio was significantly associated with mortality both in univ

202 se concentration, stress hyperglycemia ratio was significantly associated with mortality in patients

203 Admission glucose was significantly associated with mortality in univariat

204 here were differences in which comorbidities were significantly associated with mortality between age

205 than men to report headache, while older age was significantly associated with musculoskeletal and vi

206 Perceived comfort level with PPE standards was significantly associated with N95 respirator mask av

207 ive pneumonia accounted for 61% of cases and was significantly associated with neoadjuvant chemoradia

208 show that origins of acoustic communication are significantly associated with nocturnal activity.

209 MLR was significantly associated with number of sites at the

210 , disc area, and signal strength of the scan were significantly associated with OCT measurements.

211 Shorter telomere length was significantly associated with older age, male sex, s

212 nd presence of occlusal wear facets on teeth were significantly associated with one of the two outcom

213 2 SNP sets that identified 727 gene loci and were significantly associated with one or more of the ch

214 stant enterococcal infection or colonization is significantly associated with oral vancomycin.

215 Probability of transplantation is significantly associated with organ offer acceptance

216 A-617 was proven by multivariate analyses to be significantly associated with OS and PFS.

217 BSI after treatment, compared with baseline, was significantly associated with OS (P < 0.0001), with

218 lymph node TLG, PALN TLG, and PALN SUV(max) were significantly associated with OS (P < 0.005).

219 IPI risk category, NCCN-IPI risk categories were significantly associated with OS (P <= .01); the re

220 ariates, aBSI (P = 0.01) and ALP (P = 0.001) were significantly associated with OS, whereas PSA value

221 s, endotracheal tube size (<= 7.5 vs >= 8.0) was significantly associated with patients exhibiting an

222 Both TBI and PTSD were significantly associated with PD in single-risk fac

223 ments were recorded in 169 (49.1%) cases and were significantly associated with perinatal outcome, in

224 revealed that higher cortisol and CRP levels were significantly associated with persistent depressive

225 In multivariate analysis, only Dmax(patient) was significantly associated with PFS (P = 0.0014) where

226 aled that PHD finger protein 8 (PHF8, KDM7B) was significantly associated with poor clinical outcome

227 available cohorts, high expression of USP11 was significantly associated with poor survival in ERalp

228 B12 use both before and during chemotherapy was significantly associated with poorer disease-free su

229 Travel distance was significantly associated with post lung transplant s

230 acute and chronic graft versus host disease were significantly associated with post-HCT AIC.

231 wer IOP change, and lower corneal hysteresis were significantly associated with posterior ALCS displa

232 In gene-specific analyses, only DNMT3A CHIP was significantly associated with premature menopause.

233 Human papillomavirus was significantly associated with preterm birth (age-adj

234 POAG was significantly associated with prior HTN (OR 1.31, 95

235 phenotypes within the tumor microenvironment are significantly associated with prognosis and immune e

236 l but not type of antistaphylococcal therapy was significantly associated with prolonged bacteremia a

237 neutralizing antibodies from prior infection was significantly associated with protection against rei

238 ronary artery disease and years of education were significantly associated with psychiatric disorders

239 ence to Western and prudent dietary patterns was significantly associated with radiographic and sympt

240 Human laboratory-confirmed cases were significantly associated with rat IgG positivity an

241 Intraocular pressure was significantly associated with rates of progressive R

242 ion models, a greater area deprivation index was significantly associated with readmissions (beta, 0.

243 8(1.52-6.24 95% CI)] at index colonoscopy to be significantly associated with recurrence of advanced

244 Use of iron during chemotherapy was significantly associated with recurrence (adjHR, 1.7

245 or lower respiratory tract infection (LRTI) was significantly associated with reduced FEV1 and FVC (

246 The paternal transmitted birth weight score was significantly associated with reduced gestational du

247 Active S. stercoralis infection was significantly associated with reduced pre-treatment

248 d.Measurements and Main Results: Weight loss was significantly associated with reductions in tongue f

249 scovered that increases in the provider COCI were significantly associated with reductions in health

250 al patterns of gray matter differences in CD were significantly associated with regional differences

251 flet toward the apex in most young patients, was significantly associated with sarcomere mutations in

252 Genes that were significantly associated with scarring progression

253 ition during the second and third trimesters was significantly associated with SCH in pregnant Chines

254 variants within the 22q11.2 deletion region were significantly associated with schizophrenia.

255 t, 284 and 279 candidate genes were found to be significantly associated with seed oil-related traits

256 Importantly, these structural alterations were significantly associated with sensory function with

257 34), CHD (P < 0.001), and hs-CRP (P < 0.001) were significantly associated with serum ADMA, whereas i

258 We found the derived allele was significantly associated with several adiposity trai

259 Hyperferritinemia was significantly associated with severe acute kidney in

260 roblems, especially the depressive problems, were significantly associated with short sleep duration

261 Furthermore, elevated DOCK6 expression was significantly associated with shorter cumulative sur

262 ate, regression, and lymphovascular invasion were significantly associated with SN status.

263 s were compared; however, neonatal mortality was significantly associated with SO2 (1.207 [1.154, 1.2

264 -analysis which demonstrated that those SNPs were significantly associated with SSRI treatment outcom

265 Clonal loss of functional TP53 is significantly associated with subclonal gains of MCL-

266 Index scores are significantly associated with suboptimal retention a

267 Baseline IOP > 18 mmHg was significantly associated with success both at 2 and

268 he target sample, PRS for self-harm ideation were significantly associated with suicide thoughts and

269 itude higher than >500 m, and GDP per capita were significantly associated with survival in all patie

270 sis/gluconeogenesis-related metabolites that was significantly associated with T2D risk in a Mediterr

271 Several SNP were significantly associated with taxa at the three tim

272 1 SNP sets that identified 736 gene loci and were significantly associated with temperament.

273 and endoscopic sphincterotomy were found to be significantly associated with the development of PEP.

274 the fatty acid desaturase 3 (FADS3) gene to be significantly associated with the plasma d18:2/d18:1

275 excluded, belong to poor class were found to be significantly associated with the poor child health o

276 f the ECG signal (e.g., T-wave, ST-interval) is significantly associated with the hypoglycemic event

277 The presence of a left common trunk was significantly associated with the absence of ECs (29

278 Weekly measured FVIII activity was significantly associated with the bleeding rate, but

279 9; CDH10, P = 1.2 x 10-8) and one locus that was significantly associated with the metabolic subtype

280 etformin concentration threshold of 9.9 mg/L was significantly associated with the occurrence of lact

281 on in the strength of rich-club connectivity was significantly associated with the participants' perf

282 le mixed-effects regression, brain stiffness was significantly associated with the presence of MRI le

283 resence of true progression on the RNFL scan was significantly associated with the presence of true p

284 In conclusion, maternal GWG was significantly associated with the risk of preterm bi

285 s had preoperative adduction deficits, which were significantly associated with the finding of an int

286 many genes encoding mediators of parasitism were significantly associated with the level and stage o

287 iral load, and the number of sexual partners were significantly associated with the patient's CD4 cou

288 ysis, severe glaucoma, hypertension, and age were significantly associated with the presence of artif

289 T360 and lower levels of Rothia dentocariosa were significantly associated with the presence of perio

290 All scores were significantly associated with the primary outcome (

291 ept for ALT (alanine transaminase), all GRSs were significantly associated with their traits.

292 eater number of antihypertensive medications was significantly associated with thinner average RNFL (

293 Cases were significantly associated with travel to either Euro

294 set of three genes; CD36, FAPB3 and RAETE1; were significantly associated with TTP.

295 down-regulated metallothionein-family genes are significantly associated with tumor invasion.

296 and FGF9/FGFR3 expression in human neck fat is significantly associated with UCP1 expression.

297 aring these biopsies to matched controls, TE was significantly associated with UOC (odds ratio 2.69;

298 Refractive error (myopia or hyperopia) was significantly associated with VI in the eye-level an

299 indicating that higher expression of miR-21 was significantly associated with worse OS in glioma pat

300 DCP EAA was significantly associated with worse visual acuity (r