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   1 tetraenoic acid [15(S)-HETE] and 15-oxo-ETE, confirming the role of 15-LO-1 in mediating AA metabolit
     2 ylgeranyl pyrophosphate reversed the effect, confirming the role of 3-hydroxy-3-methylglutaryl coenzy
  
     4    The analysis of in frame deletion mutants confirmed the role of a hydroxymethylglutaryl-coenzyme A
  
  
     7 iated with lipid responses to SRL treatment, confirming the role of ABCB1 gene in SRL pharmacokinetic
  
  
  
    11 logical studies and animal models to further confirm the role of ADE in the development of congenital
    12 rophages from A(3)-/- but not A(2A)-/- mice, confirming the role of adenosine A(2A) receptors in this
  
    14 y prevented effects on photosynthetic yield, confirming the role of Agd as a cause of the observed ef
  
    16 all pathogenic repeat carrier brain samples, confirming the role of altered histone methylation in di
    17 ble-blind, randomized controlled trials have confirmed the role of alternative tumour necrosis factor
    18 es and density functional theory simulations confirmed the role of amine groups for stabilizing key i
    19   Mutational studies based on this structure confirmed the role of amino acid residues in the capsid 
  
  
  
  
  
  
    26 B::lacZ and gdhA::lacZ translational fusions confirmed the role of ArgR in mediating arginine repress
  
  
  
  
    31 ile in patients with previously treated MZL, confirming the role of BCR signaling in this malignancy.
    32 dministration of an LTB4 receptor antagonist confirming the role of BLT1 in CD8+ T cell-mediated AHR.
    33  BMP inhibitor noggin prevents the disorder, confirming the role of BMP4 in the pathogenesis of the d
    34 Consistently, RT-PCR and proliferation assay confirmed the role of both genes in cell cycle progressi
  
  
    37 delivered into the upper genital tract, both confirming the role of C5 in promoting hydrosalpinx and 
    38 ish blood and by a fish macrophage cell line confirmed the role of capsule in virulence and highlight
  
    40 tion of CBFbeta in an EBNA3C-conditional LCL confirmed the role of CBF in the regulation of EBNA3C-in
  
  
    43 y of the model is demonstrated by accurately confirming the role of CD4 help for antibody persistence
  
  
    46 th the expansion of CD8 tetramer(+) T cells, confirming the role of CD8 T cells in this treatment str
  
  
  
    50 l overlap among CESTA and its homologues and confirmed the role of CESTA in the positive control of B
    51  components of the pathway are conserved and confirm the role of CgPHO81, CgPHO80, CgPHO4, and CgMSN5
    52   Application to data from England and Wales confirms the role of children as key infection spreaders
  
    54 e, we use an in vitro pre-clinical model and confirm the role of cIAP1 in invasion and the role of cI
    55 ta and canonical WNT/beta-CATENIN signaling, confirming the roles of classical signaling in human neu
  
  
  
    59    Subsequent experiments in mammalian cells confirmed the role of conserved extracellular threonine 
  
    61 lar mechanism underlying ADCC, which further confirms the role of Cx50 in the maintenance of human le
    62 nt of micro 1 (Cys679 substituted by serine) confirmed the role of Cys679 and suggested that the ds b
    63  of tumor necrosis factor alpha (TNF-alpha), confirming the role of cystatin E/M in the regulation of
    64 sing radioiodinated D-KRYRR and L-KRYRR, and confirmed the role of D-amino acids in enhancing tumor u
  
  
  
    68 somni transmigration across BAT2 monolayers, confirming the role of DR2/Fic in pathogenesis and corre
  
  
  
    72 agenesis, CovR binding was reduced in vitro, confirming the role of each thymine pair in binding.    
  
    74 elevates pol III transcript expression, thus confirming the role of endogenous Maf1 as an inhibitor o
    75 o negatively affect mTOR-FKBP38 interaction, confirming the role of endogenous PA in this regulation.
  
  
    78  ERM kinase of importance in lymphocytes and confirm the role of ERM phosphorylation in regulating ce
    79  BQ788 blocked the effects of IRL-1620, thus confirming the role of ETB receptors in the neurovascula
  
  
  
  
    84 nts with human bone marrow stroma cocultures confirm the role of fibronectin ligation in maintaining 
  
  
  
  
  
  
  
  
  
  
    95 ecretion; the effect on insulin and glucagon confirms the role of GLP-1 in glycemic control through i
    96 et morphology, and gene expression, and they confirm the role of glucagon as a tonic insulin antagoni
    97 covery from agonist-induced desensitization, confirming the role of gravin in organization of G-prote
    98 on of (18)O into the Asp carboxyl side chain confirming the role of H2O2 in the oxidation of the Met 
    99 d isozyme-specific small interfering RNAs to confirm the role of HDACs 1 and 6 as key mediators in fa
   100   Knockdown and overexpression lines of HER2 confirmed the role of HER2, which encodes an oxidoreduct
   101 l novel capabilities of human FcgammaRI that confirm the role of high-affinity IgG receptors in vivo.
   102 rt transplanted over the course of 3 decades confirms the role of HLA-identical sibling transplantati
  
   104 s NPM1/NRAS-G12D-mutant AML and functionally confirm the role of HOXA genes in NPM1c-driven AML.     
  
  
  
   108 anti-IL-7 monoclonal antibody (MAb) in vivo, confirmed the role of IL-7 protein in the observed TgB p
   109 nd Vegf expression and new vessel formation, confirming the role of IL-6 trans-signaling in these pro
  
  
  
   113 process of tripartite ICE integration and to confirm the role of integrase genes intS, intM, and intG
  
  
   116 a block in IL-4, IL-5, and IL-13 production, confirming the role of IRE1alpha in the regulation of IL
   117 V-1 constructed by site-directed mutagenesis confirmed the role of K103N, G190S, and Y188L substituti
   118 uclease complex, allowing us to identify and confirm the role of key residues (Phe123, Met256, and Ty
  
   120 at overexpress adrenergic alpha2A receptors, confirming the role of leucine in insulin secretion.    
  
   122 nts defective in relevant defense mechanisms confirmed the role of LPG in oxidant resistance but call
  
  
  
  
   127  (M1R) exhibited enhanced neurite outgrowth, confirming the role of M1R in tonic suppression of axona
   128 down experiments on ProGENI-identified genes confirmed the role of many new genes in sensitivity to t
   129 king STAT1s or the type I IFN receptor chain confirmed the role of MAPKKs and IRF7 in Tat-mediated mo
  
  
  
   133 icted P1 inhibitory reactive site amino acid confirmed the role of Met(26) in mediating inhibition of
  
   135 inhibitor of DNA methyltransferases, further confirmed the role of methylation in PTPRO gene expressi
  
   137  gene that causes recessive form of CMT6 and confirms the role of mitochondrial dysfunction in this c
   138 ith mutant MRE11, we experimentally tried to confirm the role of MRE11 in conferring sensitivity to P
   139 ramework of the developing brain and further confirms the role of mRNA translation in autism pathogen
   140 dria results in defective bacterial killing, confirming the role of mROS in bactericidal activity.   
   141 re elevated in Msh2-deficient ES cell lines, confirming the role of Msh2 in blocking recombination be
   142  reproduced the effect of rapamycin, thereby confirming the role of mTOR and of S6K in the acquired r
   143 ockout and transgenic mouse studies, further confirmed the role of mu-calpain in the endothelial adhe
   144 ing, identifying new driver genes while also confirming the role of myeloid differentiation primary r
  
  
  
  
   149  growth and invasive morphology in Matrigel, confirming the role of NF-kappaB in epithelial to mesenc
  
   151 inant IL-1beta, and IL-1 receptor antagonist confirmed the role of NLRP3 inflammasome-dependent IL-1b
  
  
  
   155 ne profiling of FACS-purified photoreceptors confirmed the role of NR2E3 as a strong suppressor of co
   156  functions are limited when RNA is modified, confirming the role of nucleoside modifications in suppr
  
  
   159 ilm formation in the murine intestinal tract confirmed the role of one of the fimH alleles in this pr
   160 f ORF7a leads to a much greater restriction, confirming the role of ORF7a as an inhibitor of BST-2.  
   161 pidly after injury than control plants, thus confirming the role of P-proteins in sieve tube sealing.
   162 ligodeoxynucleotides and integrin activation confirmed the role of P311 in supporting migration of ma
  
  
   165 tion of conserved ApiAP2 genes in Plasmodium confirmed the role of PbAP2-G and revealed a second ApiA
   166      Finally, we present a novel method that confirms the role of PcAce2 in modulating organism virul
  
  
   169  in vivo and in vitro ubiquitination studies confirm the role of PDLIM2 in formation and degradation 
   170 nt on the pheromone receptors Ste2 and Ste3, confirming the role of pheromone signalling in sexual bi
   171 ailed phenotypic analysis of a phmyb1 mutant confirmed the role of PhMYB1 in the control of cell morp
  
  
   174  loss of secretin function, and additionally confirms the role of PilT as a conditional antagonist of
   175 retreated with the PKC inhibitor Ro-31-8220, confirming the role of PKC in mediating the PMA effect o
  
  
   178 ymphoid organs are almost devoid of B cells, confirming the role of positive selection by Ag in the d
  
  
   181 to trigger the alpha-to-beta transformation, confirms the roles of previously indicated residues E48 
  
   183 tion of genetically engineered animal models confirms the role of PRKAR1A as a tumour suppressor and 
  
   185 face CD45 and restored phosphatase activity, confirming the role of PU.1 in the positive regulation o
  
  
  
  
  
   191  usefulness of the reverse genetic system to confirm the role of residues or proteins in coronavirus 
  
   193 ric analysis of several active site variants confirmed the roles of residues critical to the function
  
  
   196 involvement of MEK/ERK signaling and further confirm the role of ROS/superoxides in POX-induced apopt
  
  
  
  
  
  
  
   204 ffected by the sl(7) mutation, these results confirm the role of Sl in RTK signaling and provide evid
  
  
  
   208 ing activation on this 3D structure, we have confirmed the roles of specialized myofiber tracts such 
   209 xpressed protein, has the power to reveal or confirm the roles of specific components of signaling pa
  
   211 ldehyde from CO hydrogenation on Ni(110) and confirm the role of subsurface hydrogen in the mechanism
   212 diasis resulting from T(H)17 deficiency have confirmed the role of T(H)17 cells and T(H)17 cytokines 
   213 essing an inactive mutant (DeltaZn/DeltaZn), confirming the role of TACE in PMA-induced c-Kit sheddin
  
  
   216 tions had better outcomes 90 days after ICH, confirming the role of TGF-beta1 in functional recovery 
  
   218 tative PCR, and pyrosequencing, were used to confirm the role of the candidate gene in determining sp
   219 itoring PA reassortment in seasonal flu, and confirm the role of the Caspase-1 gene in influenza path
  
  
  
  
  
  
  
  
   228 s in primary progressive aphasia and further confirm the role of the uncinate fasciculus in semantic 
  
   230  mutational analysis of the miR-155 promoter confirmed the role of the Ets2 binding site proximal to 
  
  
  
  
  
   236 ing B cell-specific knockdown strategies, we confirmed the role of the miR-155 target Aicda (activati
   237  and cell surface/solid-phase binding assays confirmed the role of the NGR domain in promoting AAV2-i
  
   239 f oleosin in a range of sec61 mutant alleles confirmed the role of the SEC61 translocon in insertion 
   240 truction of bona fide sat operon mutants and confirmed the role of the SRP pathway in acid resistance
   241 tion were inhibited by unconjugated aptamer, confirming the role of the aptamer in receptor-mediated 
   242 mide blocked the modulatory effects of ACTH, confirming the role of the cAMP/PKA pathway in microEOD 
   243 and Madin-Darby canine kidney Tet-Off cells, confirming the role of the carboxyl-terminal phosphoryla
   244  catalytic activity and acetate competition, confirming the role of the cavity in acetate escape.    
   245  was converted into a classical endo enzyme, confirming the role of the extended Arg(203)-Ala(230) lo
   246 ults in a constitutively activated integrin, confirming the role of the extracellular clasp in restra
   247  the cells to 3-nitropropionic acid (3-NPA), confirming the role of the nitronate monooxygenase prote
  
   249 istance defect in the counter-immune mutant, confirming the role of the protein in resistance to macr
   250 and 190 copies/100,000 cells, respectively), confirming the role of the thymus in maintaining the per
   251    Furthermore, electron population analysis confirms the role of the alkene as a "stepping stone" fo
  
  
   254 irection and localization of these responses confirms the role of the mu-opioid receptor system in th
   255 onal overlap among members of the family and confirm the role of these phosphatases in the control of
   256 ndings justify future prospective studies to confirm the roles of these molecules in mediating chemot
  
   258 nd Uhpra1, and their subsequent replacement, confirmed the role of these genes in initiation of the s
   259 on and quantification by confocal microscopy confirmed the role of these genes in the maturation of t
   260 mains IIIS6 and IVS6 of alpha(1CII) subunits confirmed the role of these L-type-specific amino acid r
  
  
  
   264 s that are crucial for c-di-GMP binding, and confirmed the roles of these residues through biochemica
   265  and accuracy of single nose poke responses, confirming the role of these areas in guiding responses 
   266 ce conditions but not for random conditions, confirming the role of these regions in the representati
   267  synaptic potentiation in an intact circuit, confirming the role of these vesicular SNAREs in setting
  
  
  
  
  
   273   The phenotypes of the Scnm1Delta3-5 mutant confirm the role of this splice factor in processing the
   274 sure that lead normal cells to tumorigenesis confirm the role of this steroid hormone in cancer initi
   275 ing the individual RRM domains from hnRNP LL confirm the role of this transcription factor in activat
  
   277  for the propane monooxygenase enzyme (PrMO) confirmed the role of this enzyme in the biotransformati
   278 ntation using a recombinant wild-type allele confirmed the role of this mutation in the cytadherence 
  
   280 reversed the anti-apoptotic effects of NRG4, confirming the role of this cascade in NRG4-induced cell
   281 ion probability was highly significant, thus confirming the role of this DUT mutation in this syndrom
   282 ibody shifted nuclear protein-DNA complexes, confirming the role of this factor in regulating the exp
  
   284 value and a much lower catalytic efficiency, confirming the role of this residue in substrate binding
   285 ocked proton transfer by binding to Glu-282, confirming the role of this residue in the identified pa
   286 egregating with macular dystrophy phenotypes confirms the role of this gene in a subset of dominant m
   287 etic complementation of a Thf1 knockout line confirms the role of this gene in chloroplast and leaf d
   288 ndent, tissue-specific growth regulation and confirmed the roles of three such genes in the phytochro
  
   290 did those from their wild type counterparts, confirming the role of TopIIbeta in neurite outgrowth.  
  
   292 ometric evidence in vivo as well as in vitro confirmed the role of transient receptor potential chann
  
  
  
  
   297 complex mutation linked to human disease and confirms the role of very short telomeres as a diagnosti
   298 ocked down transgenic tobacco plant analysis confirmed the role of XET gene in roots growth and droug
  
   300 eased in ZAT6 overexpressing plants, thereby confirming the role of ZAT6 in regulating Pi homeostasis
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