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   1 y cohorts (one discovery and one replication data set).                                              
     2  cancer cell lines and applied CERES to this data set.                                               
     3 ubmitted for 51 466 patients in the pharmacy data set.                                               
     4 n Evaluation of Cancers of the Thorax) NSCLC data set.                                               
     5 e performance on our data and an independent data set.                                               
     6 al was also significant in each contributing data set.                                               
     7 Scientific Registry of Transplant Recipients data set.                                               
     8 pplied this method to the TCGA breast cancer data set.                                               
     9 l and on an internal and external validation data set.                                               
    10 was biologically validated in an independent data set.                                               
    11  attributes are stored and collected for the data set.                                               
    12  fixed cells to provide a large and detailed data set.                                               
    13 lidated in a similar analysis of an external data set.                                               
    14  in the cell line panel and in a human tumor data set.                                               
    15  strains and to compare results for the four data sets.                                              
    16  limiting their application to small, single data sets.                                              
    17 at combined case-control and cross-sectional data sets.                                              
    18 portant information from complex biochemical data sets.                                              
    19 t to be applied easily to other large fossil data sets.                                              
    20 d increased the concordance with post-mortem data sets.                                              
    21  be applied to study PC development in large data sets.                                              
    22 oach for investigating novel aspects of eQTL data sets.                                              
    23 y of the method is validated using simulated data sets.                                              
    24 y, validate and quantify peptidoforms in DIA data sets.                                              
    25 quencing data sets and 637 methylation array data sets.                                              
    26 hallenges in applying this approach to large data sets.                                              
    27 framework with applications to two empirical data sets.                                              
    28 verified in several independent public ccRCC data sets.                                              
    29  a variety of germline, cancer and stem cell data sets.                                              
    30  = 33820) or external validation (n = 54716) data sets.                                              
    31 711) and out-of-sample replication (n = 477) data sets.                                              
    32 om comorbidity data recorded in longitudinal data sets.                                              
    33 tions and real iCLIP and single-cell RNA-seq data sets.                                              
    34  classifier design using small, unstructured data sets.                                              
    35 t biological knowledge from high-dimensional data sets.                                              
    36 roblems with use of other publicly available data sets.                                              
    37 om the modENCODE consortium and other public data sets.                                              
    38 probabilities using analysis of hydrological data sets.                                              
    39 onsensus transcriptome from multiple RNA-seq data sets.                                              
    40 decisions, and should be evaluated in larger data sets.                                              
    41 for animal model analyses of wild population data sets.                                              
    42 ss of the Bayesian approach for the sparsest data sets.                                              
    43                      We fit our model to two data sets.                                              
    44 e determination of somatic variants in these data sets.                                              
    45 nisms, some patterns emerge from these large data sets.                                              
    46 e significance that replicate in independent data sets.                                              
    47 ning methods, and (3) balancing the training data sets.                                              
    48 rocessing large immune repertoire sequencing data sets.                                              
    49 bination of time-activity and meteorological data sets.                                              
    50  HRGP classes in existing and emerging omics data sets.                                              
    51 of adding sequenced genomes to transcriptome data sets.                                              
    52 deAtlas releasing the results of reprocessed data sets.                                              
    53  of interest and excellent coregistration of data sets.                                              
    54 T for accuracy and reliability using several data sets.                                              
    55 enced 10x Genomics sarcoma and breast cancer data sets.                                              
    56 c resonance imaging scans were obtained from Data set 1: 155 patients with schizophrenia (mean durati
    57 (P<0.05) in an independent post-mortem DLPFC data set (182 schizophrenia and 212 control subjects), a
  
    59 ess of 7 years) and 79 healthy controls, and Data set 2: an independent cohort of 46 schizophrenia pa
  
  
    62 reveals novel variants, missed in short-read data sets, a large proportion of which are retrotranspos
    63 nerating accurate segmentations of large MSI data sets acquired on the newest generation of MSI instr
    64 bDEMC 2.0 documents 209 expression profiling data sets across 36 cancer types and 73 subtypes, and a 
  
  
    67 ations of training on available experimental data sets, alternative approaches that utilize propertie
  
    69 r analysis of The Cancer Genome Atlas (TCGA) data set and observe that bi-allelic pathogenic alterati
    70 -species 210-genome 96-sample synthetic mock data set and then applied it to the Tara Oceans microbio
  
    72 trated on simulated data, various biomedical data sets and a clinical data set, to which diverse ML m
  
  
    75 We tested LAIT using both simulated and real data sets and demonstrated that LAIT provides convenienc
    76 se alterations in multiple independent HNSCC data sets and show that, along with previously described
    77 dure on three experimental and 300 simulated data sets and showed that it provides robust fits of the
    78 ogic studies are reproducible include making data sets and software available to other researchers so
    79 hich decreases the sizes of the intersecting data sets and the potential for biological insights.    
  
    81 ysis of 61 whole-genome bisulfite sequencing data sets and validation with 101 reduced-representation
    82 eam analysis of large, heterogeneous RNA-Seq data sets and we demonstrate its use with data from the 
    83 orrelations was generally reduced in imputed data sets, and this effect increased with the amount of 
    84 demonstrated in 27 independent breast cancer data sets, and through visualization of the data in the 
  
    86 classification to multinomial mixtures where data sets are both small and unlabeled, enables superior
    87 er molecules inside the pore, both LT and RT data sets are consistent with the positions observed in 
    88 , and its implementation for several RNA-Seq data sets, as well as the whole genome sequencing data t
    89 tain multidetector computed tomographic (CT) data sets at multiple radiation exposure levels within t
    90 and validated to synthesize multidetector CT data sets at multiple radiation exposure levels within t
  
  
    93 tation and by using a refined, more reliable data set, based on a new release of the ProNIT database,
  
    95  Machine Learning Repository, and a clinical data set built to determine suicide risk from the langua
    96  conclude with a discussion of how synthetic data sets can be used by researchers with cancer registr
    97 xomes sequenced, and access to the resulting data sets can provide valuable information for variant i
    98 MD in African American and European American data sets collected as part of the Yale-Penn study of th
    99     Analysis of EBV PAR-CLIP miRNA targetome data sets combined with pathway analysis revealed multip
   100 redictive deep neural network on the lincRNA data sets compared with support vector machine and tradi
   101  phylogenetically informed framework using a data set comprising > 216 000 world-wide observations of
  
   103 However, projects are generating ever-larger data sets comprising RNA-Seq data from hundreds or thous
   104     We demonstrate the approach on different data sets containing RNA-seq gene transcripton and up to
  
   106 ed prediction models by means of an election data set covering 86 countries and more than 500 electio
   107 tative SSP genes based on 144 RNA sequencing data sets covering various stages of macronutrient defic
  
  
  
  
  
  
  
   115 Statistics' period linked birth/infant death data set files for 2007-2013 for 26546503 US births thro
   116  We provide a bias corrected (*) Pic du Midi data set for 2012-2014 that shows GOM* and RM* levels in
   117 ramework on a comprehensive miRNA expression data set for alcohol dependence and identify the causal 
   118  used on a comprehensive and well-documented data set for bromamine decomposition, allowing new inter
  
  
  
   122 g and archiving and a globally comprehensive data set for onward use by the scientific community.    
  
  
   125 cells, we generated 63 chromatin interaction data sets for 37 active DNA regulatory elements that col
  
   127  peptide migration standards, collect larger data sets for modeling through the alignment of multiple
   128 Here we use three source time function (STF) data sets for subduction zone earthquakes, with moment m
   129 n gland tumor experiment, the only extensive data-set for dose response modelling with a variety of p
  
  
  
  
  
  
  
  
   138 unity from publicly available gut metagenome data sets from human populations with different geograph
  
   140  Here we exploit representative whole-genome data sets from six diverse bacterial species: Staphyloco
   141   Longitudinal cohort study using harmonized data sets from the British 1946, 1958, and 1970 national
   142  A user-friendly web database populated with data sets from The Cancer Genome Atlas (TCGA) is provide
   143 mpared with measured water concentrations in data sets from the greater Denver area, Minnesota lakes,
   144 ing simulated classifier outputs, biomedical data sets from the University of California, Irvine (UCI
   145 ithms and a data repository consisting of 13 data sets from various microscopy modalities, the challe
   146 cancer molecular profiles, including genomic data sets, from four patient cohorts identifying lncRNA 
  
  
  
  
  
   152 ree-dimensional (3D) biomolecular structural data sets have been hindered by the geometric and biolog
  
  
  
  
   157 the kauri and Atlantic marine sediment (14)C data sets, implying limited changes in deep water format
  
  
   160 s that are performed and evaluate large GWAS data sets in a reasonable amount of computation time.   
   161 thm to multiplexed droplet-based digital PCR data sets in both EvaGreen and probes-based schemes, and
  
   163 ght opportunities for researchers to use big data sets in the fields of gastroenterology and hepatolo
  
   165 ventory calculations, a harmonized inventory data set including both nominal and uncertainty data is 
  
   167 ian approach is demonstrated on a variety of data sets, including simulated classifier outputs, biome
   168 ated in breast cancer; interrogation of TCGA data set indicates that upregulation of DHX9 in breast c
   169 sis (n = 52 of 1001; 5.19% in the derivation data set), indicating the need for transdiagnostic predi
  
  
  
   173 ectories of the Global Drifter Program (GDP) data set, it was found that oceanic eddies are asymmetri
   174 h expression level, and that in human tissue data sets, MAE genes show increased expression variabili
   175  a large collection of public mass cytometry data sets, measuring intra-cellular signaling proteins o
   176 The Cancer Genome Atlas (TCGA) breast cancer data set (n = 1215) to calculate previously described im
  
  
   179 by the special opportunities associated with data sets, nearly all of which have been observational, 
   180 Here we exploit a bidecadally resolved (14)C data set obtained from New Zealand kauri (Agathis austra
   181 re was no significant difference between the data sets obtained from both methods, indicating no in v
  
  
   184 ghput sequencing to assemble and interpret a data set of 143 mammoth mitochondrial genomes, sampled f
   185 tion methodologies using an aquatic toxicity data set of 3448 chemicals, compare the approaches, and 
  
  
  
  
  
  
   192  and Markov state model analysis to a 50-mus data set of molecular dynamics trajectories of the human
   193 Predictions were evaluated on an exceptional data set of plankton with 15 years of weekly samples enc
   194 ing Machine Learning methods on an extensive data set of proprietary bioactivity data combined with o
   195 melanogaster, first generating our own novel data set of sequenced MA lines and performing a meta-ana
  
   197 NAP participants and nonparticipants.Using a data set of US households' (n = 98,256 household-by-quar
  
  
   200 n tumors detected tissue-specific and shared data sets of known and candidate genes involved in cance
   201 expression data and compares them with large data sets of normal expression profiles compiled from pu
   202 t a complementary statistical analysis of 13 data sets of phytoplankton and periphyton communities ex
  
  
  
   206  British Cardiovascular Intervention Society data set on all CTO-PCI procedures performed in England 
   207 statistical analyses of a spatially resolved data set on cod eggs covering a period (1959-1993) with 
   208 MM, and BOLT-LMM, we investigate an existing data set on eye (n = 625) and skin (n = 684) color from 
  
   210 Application to several large-scale screening data sets on nuclear and mitotic cell morphologies demon
  
  
   213  successfully simulate the entire adsorption data set over all uranium loadings, pH values, and disso
   214 lity (CP) plots for spatially representative data sets, preferably containing >1000 determinations.  
  
  
  
  
  
   220 nal Cardiac Arrest Registry), an 87-question data set representing 44 centers in the United States an
  
  
   223 sed principal component analysis of the same data set revealed that dopaminergic modulation activates
   224 sion analysis of The Cancer Genome Atlas AML data set reveals that GLI3 expression is silenced in mos
  
  
  
   228 nnotator in an untargeted metabolomics human data set shows that 80% of features with high or medium 
   229 ; chemical formula; collision cross section] data sets shows that the WAF composition changes as a fu
   230 take high-precision alignment of key climate data sets spanning iceberg-rafted debris event Heinrich 
  
   232  RNA contamination, no published genome-wide data set supports the concept of delayed paternal genome
  
   234 gical diffusion can be implemented for large data sets that are distributed densely across space and 
   235 iven the availability of two tracer exchange data sets that explore pH and particle size effects, we 
  
  
  
  
  
   241 eanalysis of a published genetic and genomic data set through iFORM/eQTL gain new discoveries on the 
  
   243 e linked the United States Renal Data System data set to Medicare claims to estimate cumulative costs
  
   245 each unfolded form observed in our gas-phase data set to the disruption of specific domains within th
   246 approach to examine the potential for RADseq data sets to accurately estimate effective population si
  
   248 e, we discuss ways we can leverage molecular data sets to develop new hypotheses for disease mechanis
  
   250  HCA algorithms were performed on all of the data sets to explore the relationships between, and natu
   251  of analyzing and exploring high dimensional data sets to generate hypotheses and discovering novel i
   252 enable institutions handling massive genomic data sets to shift part of their analysis to the cloud w
  
   254 ex examples, along with programming code and data sets, to show how Bayesian analysis takes evidence 
   255 s of 11 genome-wide association case-control data sets, totalling 17,045 endometriosis cases and 191,
   256 amples in dropdowns for navigation among the data sets, utilizes human-readable configuration files t
  
   258   The Nationwide Emergency Department Sample data set was examined for temporal trends in the number 
   259  among more than 23 million people, a custom data set was obtained using the data of all patients hav
   260 hospholipids present in human serum, and the data set was used to evaluate the value of product ion m
  
   262 ngly associated with signature 3 and, in our data set, was highly enriched in basal-like breast cance
   263 idates, which did not appear in the training data set, was validated in a previous research work.    
  
  
  
  
  
  
  
  
  
  
   274 yzing over 23,000 publicly available RNA-Seq data sets, we show that Tradict is robust to noise and a
  
   276 fluence wider genome organization, our DamID data sets were contrasted with TADs and compartments.   
  
  
  
   280 , predictive variables available in national data sets were used to estimate high arsenic in unsample
  
   282 s, which compare the distributions of entire data sets, were used to determine if the ammonia removal
   283 esting issue, we implement filters to remove data sets where the hypotheses to be tested cannot achie
   284 d MetaboDIA to a clinical serum metabolomics data set, where we built a DDA-based spectral library co
  
  
   287  donor and recipient factors, based on local data sets, will be more beneficial in the Australian con
  
  
   290  and more than 500 elections, and a separate data set with extensive polling data from 146 election r
   291 es at the single-molecule level, providing a data set with large sequencing depth for the characteriz
  
   293 ced prostate cancer in 18 available clinical data sets with a total amount of 1,095 prostate samples.
   294 sting methods on both a variety of synthetic data sets with a wide range of settings, and three real 
  
  
   297 y, we reanalyzed data from seven independent data sets with totally 1079 breast cancer patients.     
   298 d was most influenced by the size of the SNP data set, with 25,000-50,000 SNPs required for accurate 
   299   After recalculating MDD PRS using MDD GWAS data sets without comorbid MDD-AD cases, significant evi
   300 sembly from a 90x coverage whole-genome Hi-C data set yielded high-resolution haplotypes (78.6% of va
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