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1 t 60 mg/m(2) (designated as the biologically effective dose).

2 T to estimate whole-body radiation exposure (effective dose).

3 ever, 11 induces hypertriglyceridemia at its effective dose.

4 at most 4% in both organ-absorbed doses and effective dose.

5 ng a reduction of the chemotherapeutic agent effective dose.

6 docetaxel, allowing a four-fold reduction in effective dose.

7 ses the focus should be on using the minimum effective dose.

8 ing technical dose descriptors and estimated effective dose.

9 should continue to receive it in the lowest effective dose.

10 with titrating controllers to the minimally effective dose.

11 n in the liver and derivation of the optimal effective dose.

12 or contrast-to-noise ratio (CNR); noise; and effective dose.

13 imaging accounted for 74% of the cumulative effective dose.

14 MBq for (64)CuCl2 translated into a 5.7-mSv effective dose.

15 e liver and bone marrow doses as well as the effective dose.

16 weighting factors were used to calculate the effective dose.

17 ithout significant normal tissue toxicity at effective doses.

18 in mice with no apparent side effects at the effective doses.

19 cells would decrease systemic toxicities at effective doses.

20 ite patients had higher cumulative estimated effective doses.

21 twice daily, which were earlier shown to be effective doses.

22 atients, although little data exist to guide effective dosing.

23 lees, with a doubling in the mean per capita effective dose (1.2 mSv vs 2.3 mSv) and the proportion o

24 al dose-length product (DLP) was 746 mGy cm (effective dose, 11.2 mSv), with a range of 307-1497 mGy

25 P of 200 mGy cm or lower (a "reduced dose") (effective dose, 3 mSv), and only 10% of institutions kep

29 10% of institutions kept DLP at 400 mGy cm (effective dose, 6 mSv) or less in at least 50% of patien

33 ex (CTDIvol), dose-length product (DLP), and effective dose, along with the interquartile range (IQR)

34 e doses reduced to 15 +/- 1 muSv/MBq for the effective dose and 103 +/- 4 muGy/MBq for the absorbed d

37 IPV shows promise as a means to decrease the effective dose and cost of IPV, but prior studies, all u

38 by the absence of studies defining the most effective dose and dose-response latency for targeting t

39 indings provide initial evidence of the most effective dose and dose-test interval for future experim

45 es the antidepressant action at behaviorally effective doses and suggest that the rapid change in cyc

46 on on the potential source of dermal NO, the effective doses and wavelengths, the responsiveness of d

47 rmine the maximum tolerated and biologically effective dose, and identify the recommended phase 2 dos

48 The resulting ventralized phenotype, the effective dose, and the NiCl(2) sensitive response perio

54 performed in 69 patients, for whom radiation effective dose averaged 0.99 mSv and study duration, 117

60 on of the AAs and calculating tumor biologic effective dose (BED) along the normal-organ MTBED limits

61 ntitumor biologic effects using biologically effective dose (BED) and equivalent uniform dose (EUD) w

62 , liver, spleen, and red marrow biologically effective doses (BEDs) for a maximal kidney BED (20 Gy2.

64 nt patient resulted in a 30% higher maternal effective dose but a 3.4-6 times lower embryo/fetal dose

71 by multiplying the dose-length product by an effective dose conversion factor of 0.014 mSv/mGy cm and

72 The prospects of achieving a submillisievert effective dose CT examination routinely are assessed.

73 eau were measured and used for a qualitative effective dose curve comparison with proton and carbon-i

74 distribution, and elimination), whereas the effective dose delivered is dependent on the delivery sy

75 he liver results in highly variable biologic effective doses depending on the modality used: a biolog

76 ctor row volume scanner and evaluate how the effective dose depends on scan mode and the calculation

84 quality, coronary segment interpretability, effective dose (ED), and diagnostic accuracy were assess

85 over the parent design in vivo with a median effective dose (ED50) of 1 mg/kg following a single dose

86 g efficiency in excess of 90%, with a median effective dose (ED50) of 1.5nM, whereas the maximum gene

88 ection of 555 MBq (15 mCi) will result in an effective dose equivalent of 5.9 mSv (0.59 rem) and a lu

89 (51)Mn in an adult human male would yield an effective dose equivalent of approximately 13.5 mSv, rou

91 ) (median [interquartile range])-fold median effective dose equivalent versus 0.57 (0.45-0.64)-fold m

93 and female phantoms, respectively), and the effective dose equivalent was 6.9 +/- 0.6 and 8.7 +/- 0.

94 uivalent versus 0.57 (0.45-0.64)-fold median effective dose equivalent was associated with lower odds

96 owed a favorable radiation dosimetry with an effective dose estimate of 0.0045 mSv/MBq, resulting in

98 timation, doses to patients are converted to effective doses, even though the International Commissio

102 s depending on the modality used: a biologic effective dose for 50% (BED50) of 115, 93, and 250 Gy fo

108 dose index volume, dose-length product, and effective dose for ASiR CT (3.0 +/- 2.0 mGy, 148 +/- 85

109 ow as 1.8 mSv, substantially underestimating effective dose for both volume and helical coronary CT a

111 ological Protection warns against the use of effective dose for epidemiologic studies or for estimati

112 unit exposure (0.04% versus 0.02% per 1-mSv effective dose for females versus males, respectively; P

116 )Rb, (86)Y, and (124)I) and the absorbed and effective doses for 21 positron-emitting labeled radiotr

118 rolled cortical impact injury, we determined effective doses for candesartan and telmisartan, their t

124 rom 10 to 200 pmol drastically decreased the effective dose from 0.0908 to 0.0184 mSv/MBq and decreas

125 conversion coefficients are used to estimate effective dose from DLP, they should be appropriate for

126 010 an average herder received an integrated effective dose from incorporated (137)Cs of about 18 mSv

128 to identify the steps required to reduce the effective dose from routine CT examinations to less than

132 apies, yet prominent side effects of BETi at effective doses have been reported in phase I clinical t

133 sociated with notable toxicity at clinically effective doses, highlighting the need for better unders

136 inhibitory concentration and the in vivo 99% effective dose in mice, establishing in vitro and in viv

140 namic analyses to determine the biologically effective dose included all patients for whom samples we

143 s indicated its lower cytotoxicity and lower effective dose inducing maximal reactivation, might be a

144 t, albeit with 4-fold potency reduction (the effective dose inhibiting 50% of the Ang II-induced maxi

148 e therapy in kidney transplant recipients is effective, dosing is conventionally adjusted empirically

149 Although method B increases the amount of effective dose, it provides high diagnostic quality imag

152 -based annual rates of radiation exposure to effective doses < or =3 mSv/year (background level of ra

153 nteractions were found between assignment to effective dose medication and publication year (t260=-5.

154 9, r=0.52, P=.001), while the mean change in effective dose medication arms decreased significantly (

155 SB-710622 and GSK931145 had lower minimum effective doses (MEDs) in the MEST test than other GlyT1

156 the normal-organ maximum-tolerated biologic effective doses (MTBEDs) arising from the combined radio

158 annual population-based rate of receiving an effective dose of >3 to 20 mSv/year was 89.0 per 1,000;

159 dose (+/-SD) was 4.5 +/- 0.5 muSv.MBq(-1)The effective dose of (11)C-GMOM is at the lower end of the

163 Injection of (111)In-ABY-025 yielded a mean effective dose of 0.15 mSv/MBq and was safe, well tolera

166 6-slice CTPA exposure resulted in a maternal effective dose of 1 mSv and an embryo/fetal dose of 0.05

170 x 1,480 MBq (80 mCi) would result in a mean effective dose of 3.7 mSv using the weighting factors of

172 exposure: median total fluoroscopy time and effective dose of 6.08 (1.51-12.36) minutes and 2.15 (0.

173 lculated radiation dose estimates yielded an effective dose of 6.3 mSv for an injected activity of 20

174 0-MBq injection of BAY 86-7548 results in an effective dose of 7.7 mSv, which could be reduced to 5.7

176 postinfection viral loads and/or a partially effective dose of a vaginal microbicide aimed at blockin

178 2013, would have received a total committed effective dose of approximately 0.95 mSv a(-1) from comb

180 omes containing H-ferritin siRNA reduced the effective dose of BCNU needed for tumor suppression by m

185 trast, ascorbate supplementation lowered the effective dose of JQ1 needed to successfully inhibit mel

187 he pain and inhibited CPP induced both by an effective dose of morphine and by a sub-threshold dose o

192 gy should also contribute to determining the effective dose of tea polyphenols in achieving better bo

194 utic doxorubicin reduces the therapeutically effective dose of the drug by more than an order of magn

196 ) groups, and then tested for behavior under effective doses of 5-HT1A receptor agonist 8-hydroxy-N,

197 Radiation dosimetry was acceptable, with effective doses of 9.5 muSv/MBq (intravenous administrat

199 turer communities toward routinely achieving effective doses of less than 1 mSv, which is well below

200 caspase activation in response to maximally effective doses of paclitaxel, a PLK1 inhibitor, or cisp

202 onizing radiation, but their contribution to effective doses of radiation in the general population i

203 th doses equivalent to approximately 100 50% effective doses of Yersinia pestis strain CO92 and necro

205 diac imaging procedures, the mean cumulative effective dose over 3 years was 23.1 mSv (range 1.5 to 5

207 nt of ABSSSIs at the 200-mg dose, the lowest effective dose, over a mean of 6.4 days of therapy.

210 CT by using the standard protocol with mean effective dose per series of 3.06 mSv (range, 1.4-7.7 mS

213 objectives of this study were to examine the effective dose range and the test-retest reliability of

214 hievable in patients and provide a plausibly effective dose range for initial phase 2 clinical studie

215 the doses tested were on the low end of the effective dose range, consistent with clinical data repo

222 ns were then performed to identify minimally effective dosing strategies to protect lower female geni

223 eroids should always aim to reach the lowest effective dose that gives the patient good asthma contro

224 ent toxicity, such that at a therapeutically effective dose there were no pathologic changes in the g

226 the specific absorbed dose (or biologically effective dose), they may also be related to discrete tu

228 y/MBq (0.473 rad/mCi), respectively, and the effective dose to 0.0149 mSv/MBq (0.0551 rem/mCi) or 0.0

231 re determined from time-activity curves, and effective doses to individual organs and the whole body

233 measure the radiation dose and estimate the effective doses to pediatric patients during CT for ches

235 ollected and fitted, and the AD and biologic effective dose values to the aortic wall and tumors were

255 ients (38.6%), for whom cumulative estimated effective dose was 121 mSv (IQR, 81-189; mean, 149 mSv).

256 n the bladder wall (32.4), and the resultant effective dose was 19.9 +/- 1.34 muSv/MBq (mean +/- SD).

261 r human biodistribution data, the calculated effective dose was 31 +/- 1 muSv/MBq, and the urinary bl

278 for the dosimetry calculation, and the mean effective dose was estimated to be 5.2 +/- 0.2 muSv/MBq

281 s reduced to 0.10 +/- 0.012 mSv/MBq, and the effective dose was reduced to 0.015 +/- 0.0010 mSv/MBq.

297 ur dosimetric analysis demonstrated a (64)Cu effective dose within the acceptable range for clinical

298 nergic drug combinations at their respective effective doses without unwanted accumulative side effec

299 a typical injected activity of 555 MBq, the effective dose would be 17.2 +/- 0.6 mSv for the 4.8-h m

300 a typical injected activity of 555 MBq, the effective dose would be 21.1 +/- 2.2 mSv for the 4.8-h i

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