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4 e fed a high fat/sucrose diet also exhibited elevated levels of activated JNK as well as enhanced p70
5 weight loss after 9 weeks, whereas mice with elevated levels of activin A lost 11% of their body weig
6 to increased stability of miRNPs along with elevated levels of Ago2-bound cytokine mRNA in Ld-infect
7 in memory, DN, and naive B cells in SLE show elevated levels of Aiolos, whereas Ikaros levels are unc
8 pared with the wild-type mice accompanied by elevated levels of alanine aminotransferase, a marker of
14 arine inhabitants of the area are exposed to elevated levels of anthropogenic underwater sound, parti
15 thway, regulated miR-125B1 and miR-29B1, and elevated levels of antioxidants glutathione S-transferas
16 and alveolar macrophage transcriptomes, and elevated levels of apoptotic endothelial cell microparti
17 We observed that beta-adrenergic activation elevated levels of approximately fifty lipid species, in
18 Moreover, ALDH(high) tumor cells expressing elevated levels of aromatase stimulated tumor/host estro
20 mosaicism in disease pathogenesis; although elevated levels of ASC, IL-6, and IL-18 in patients' ser
23 ma1-induced IL-10-producing Bregs, expressed elevated levels of B and T lymphocyte attenuator (BTLA)
27 have utility in the treatment of SLE, where elevated levels of BAFF and Aiolos may prime CD27(+) mem
28 osis tissue from patients with NF1 and found elevated levels of beta-catenin compared to unaffected b
29 sucrose consumption might be associated with elevated levels of beta-glucuronidase, an enzyme previou
31 the impacts of artificial topography contain elevated levels of biogenic elements and heavy metals, i
33 tasis but that sustained inflammation due to elevated levels of both HDPs and MRGPRX2-expressing mast
34 including ceh1, a mutant with constitutively elevated levels of both the stress-specific plastidial r
35 Wastewaters in coastal regions may contain elevated levels of bromide (Br(-)) and iodide (I(-)) fro
38 ted metabolite measurements, we found highly elevated levels of CAM-cycle enzyme transcripts and thei
39 rdingly, in the myocardium of Des(-/-) mice, elevated levels of cardiac actin correlated with alterat
44 ompanied by reduced levels of p27 as well as elevated levels of CCAAT/enhancer-binding protein beta (
45 inical specimens of glioblastoma multiforme, elevated levels of CCL2 expression correlated with reduc
47 Distinct isotope fingerprints, combined with elevated levels of CCR tracers, provide strong evidence
48 other hand, Tollip deficient neutrophils had elevated levels of CCR5, responsible for their homing to
49 reduced class-switched memory B cells and an elevated level of CD21(lo) B cells (Freiburg 1a), and ma
52 and CRAF is substantially increased under an elevated level of cellular Hsp90 and in the presence of
58 th an inflammatory response characterized by elevated levels of circulating CD14(+), CD16(+), CD4(+),
59 hat both wild-type and Per3(-/-) mice showed elevated levels of circulating corticosterone and increa
63 tosis, an antiangiogenic plasma profile, and elevated levels of circulating monocytes and T, but not
64 less atherosclerosis, despite having highly elevated levels of circulating proinflammatory cytokines
65 s associated with low-grade inflammation and elevated levels of circulating saturated fatty acids, wh
66 revealed that SLE patients had significantly elevated levels of circulating U1 and/or Y1 RNA compared
67 ion data revealed a high correlation between elevated levels of CNTD2 and decreased overall survival
69 of psychedelic phenomenology constitutes an elevated level of consciousness - as measured by neural
70 North Dakota is remarkably persistent, with elevated levels of contaminants observed in spills sites
71 lar counterparts of the viral oncogene v-Crk Elevated levels of Crk and CrkL have been observed in ma
79 n the general population and, in the case of elevated levels of depressive symptoms, persist into you
82 nts with anxiety disorders, individuals with elevated levels of dispositional anxiety are prone to in
83 ring extraskeletal tumors show significantly elevated levels of Dkk1 in bone microenvironment relativ
86 synthesis in rad53-1 cells is suppressed by elevated levels of dNTPs in vivo, and the activity of Po
87 3 is overexpressed in breast cancer and that elevated levels of DPP3 mRNA correlate with increased NR
88 the insulin signaling (IS) pathway revealed elevated levels of Drosophila insulin-like peptide 2 (Di
89 anscription factor E2F3, we demonstrate that elevated levels of E2F3 drive ectopic proliferation in m
92 and other epithelial tumors associated with elevated levels of EGFR and especially those demonstrati
96 e in M-ILK-deficient mice is correlated with elevated levels of epithelial Stat3 activation and proli
99 xenografts and DEN-induced-HCC tumors showed elevated levels of ERK, RSK, ELK1 and DR5 along with dec
100 location-specific information that revealed elevated levels of essential lipids to be related to inf
101 differential cholesterol profile, including elevated levels of esterified cholesterol, that is consi
103 oliferation-infected primary B cells express elevated levels of factors associated with plasma cell (
105 onfirmed undiagnosed diabetes was defined as elevated levels of fasting glucose (>/=7.0 mmol/L [>/=12
106 secretion of glucagon and insulin positions elevated levels of fatty acids as potential triggering f
116 aT- and Th17-cells; yet in the CNV eye, only elevated levels of gammadeltaT-cells were observed.
117 p with early replicating fragile sites, show elevated levels of gammaH2AX, and suffer frequent mutati
120 nal activity by whole-cell patch-clamp shows elevated levels of glutamatergic transmission and change
121 in the chorioamnion was also associated with elevated levels of granulocyte colony-stimulating factor
122 in increased spontaneous DNA damage foci and elevated levels of H2AK15ub and impairs DNA damage respo
124 taining, and HGF ELISA assays confirmed that elevated levels of HGF protein were present only in U87M
127 eiofaunal species have been reported to have elevated levels of horizontal gene transfer (HGT) events
128 l proliferation and carcinogenesis resulting elevated levels of host antibodies (e.g., anti-HPV16 E7
129 ound that HP1gamma is upregulated in PCa and elevated levels of HP1gamma in PCa predict poor outcome.
130 ae as a model eukaryote, we demonstrate that elevated levels of Hsp90 attenuate efficient DNA damage
132 essing hTDP1 and rhabdomyosarcoma cells with elevated levels of hTdp1 were more sensitive to histone
136 hat decreased Herpud1 protein levels lead to elevated levels of hypertrophic markers in cultured rat
138 hypersensitivity skin of Sash mice exhibited elevated levels of IFN-gamma, IL-17alpha, and IL-23, as
139 implanted with MPM cells expressing EPCR had elevated levels of IFNgamma and TNFalpha compared to mic
141 number of these B cell subsets, we detected elevated levels of IgG3 natural Abs and a striking incre
142 ternatively-activated macrophages, displayed elevated levels of IL-13, and extensive fibrosis, wherea
144 d disease severity, which is associated with elevated levels of IL-1beta and checkpoint kinase 1 phos
145 ated with the activation of inflammasome and elevated levels of IL-1beta at primary and metastatic si
146 combined deletions of YopJ and YopM induces elevated levels of IL-1beta/IL-18 in vitro and in vivo a
149 who previously were PWID continue to harbor elevated levels of immune activation, as defined by incr
150 of refractory/relapsed AML patients contains elevated levels of immunosuppressive exosomes which inte
153 of the cytosolic protein damage sensor HSF1, elevated levels of K48-polyubiquitinated cytoplasmic pro
154 , leukopenia in 59%; lymphopenia in 45%; and elevated levels of lactate dehydrogenase in 82%, asparta
155 Although single HSP90 mutants showed subtly elevated levels of lesions, double mutant analysis disag
156 expression significantly correlated with the elevated levels of Lin28B expression and subsequently in
157 onset retinal degeneration, associated with elevated levels of lipofuscin and its bis-retinoid compo
158 Microbial translocation, characterized by elevated levels of lipopolysaccharide (LPS) and related
159 tered microbiota metagenome characterized by elevated levels of lipopolysaccharide and flagellin.
160 -mediated KDM1A eviction was associated with elevated levels of local histone H3 lysine 4 dimethylati
161 etic disorder, is characterized by extremely elevated levels of low-density lipoprotein cholesterol (
162 ra from symptomatic pregnant patients showed elevated levels of M2-skewed immunosuppressive cytokines
164 n NF2-mutant cells renders them sensitive to elevated levels of malonyl-CoA, as occurs following bloc
165 Placentas from preterm Nrf2(-/-) mice showed elevated levels of markers of inflammation, oxidative st
166 at bexarotene treatment reduced neuron loss, elevated levels of markers of synaptic integrity that wa
167 llergy was associated with increased odds of elevated levels of maternal-reported symptoms of depress
171 is a functional polymorphism that results in elevated levels of MDM2 (due to enhanced SP1 binding to
173 g treatment of S. stercoralis infection, the elevated levels of microbial translocation markers, acut
175 ing mneP are Mn(II) sensitive and accumulate elevated levels of Mn(II), and these effects are exacerb
177 et-like cells were depleted of mucus and had elevated levels of MUC2 mRNA expression after G. duodena
179 e transcriptional profiles and significantly elevated levels of multiple pro-inflammatory molecules.
180 the hot-spot p53R172H mutation described an elevated level of mutant p53 in non-cancerous mouse tiss
181 ugh mitochondrial genomes (mtDNA) accumulate elevated levels of mutations in cancer cells, the origin
182 xpression led to high expansion activity and elevated levels of MutSbeta complex, indicating that Mut
183 em from other breast cancer cells, including elevated levels of N-acetylaspartate, a metabolite prima
184 ults in increased transcription of c-Myb and elevated levels of neutrophil infiltration, thereby alle
185 elated kinase A (TrkA) is linked to pain and elevated levels of NGF (the ligand for TrkA) are associa
186 n contrast, immune-intact 5xfAD mice exhibit elevated levels of nonamyloid reactive IgGs in associati
190 ions found in SPG5 patients, indicating that elevated levels of oxysterols might be key pathogenic fa
194 n, people with prediabetes had significantly elevated levels of PDFF and total and visceral fat.
195 Psen1-/- cells, and this was associated with elevated levels of phospho-p38 consistent with decreased
197 essive MS patients exhibited a significantly elevated level of phosphorylated NF-kappaB (p-P65) follo
199 tivity, a marker of cellular senescence; and elevated levels of phosphorylated H2AX (gamma-H2A.X), a
200 mutations in the kinase domain that lead to elevated levels of PI(3,5)P2 and impair the interaction
201 ify mutations in the CCR domain that lead to elevated levels of PI(3,5)P2 Together these findings rev
203 ived cultures contain approximately 1.5-fold elevated levels of PMP22 mRNA, exhibit reduced mitotic p
207 of macrophages with damaged RPE also elicits elevated levels of pro-angiogenic proteins that promote
208 exhibit high proportions of immune cells and elevated levels of pro-inflammatory cytokines predict po
209 Cerebral spinal fluid analysis revealed elevated levels of proinflammatory cytokines before trea
210 onists and (10)Panx1 and are associated with elevated levels of proinflammatory cytokines in cord sli
211 ns causes immune activation characterized by elevated levels of proinflammatory cytokines, including
212 in the developing brain have indicated that elevated levels of proinflammatory mediators leading to
213 lated, as in lactating mice with chronically elevated levels of prolactin, the rate of (125)I-prolact
215 ation, reduced markers of T-cell exhaustion, elevated levels of proteins associated with antigen pres
217 revealed that val1 mutant seeds accumulated elevated levels of proteins compared with the wild type,
220 athione depletion and associated with highly elevated levels of reactive oxygen species and induction
221 sed requirement of ubiquinone is to mitigate elevated levels of reactive oxygen species generated by
222 opmental and neurological abnormalities, and elevated levels of reactive oxygen species have been fou
223 a have abnormal membrane potentials, produce elevated levels of reactive oxygen species, are fragment
225 ve stress and PRP-overexpressing plants have elevated levels of reactive oxygen species, PRP may conn
226 riched breast carcinomas display evidence of elevated levels of replication stress-associated DNA dam
229 h ASD and typically developing controls, and elevated levels of sAPPalpha in ASD and FXS vs. CONTROLS
233 in an asymptomatic individual who exhibited elevated levels of serum autoantibodies and defective pe
235 s and plasmablasts in the spleen, and led to elevated levels of serum IgM and enhanced renal glomerul
236 expression of vanin-1 in skin and blood and elevated levels of serum pantothenic acid that correlate
241 ch MLL2 gene deletion can be induced display elevated levels of sister chromatid exchange, gross chro
242 affinity maturation occurred as evidenced by elevated levels of somatic hypermutation (SHM) in Ab seq
244 ing a delay in epiboly, depleted S1P levels, elevated levels of sphingosine, and resistance to sphing
245 t mice with reduced levels of MDC1 showed an elevated level of spontaneous tumors in aged animals.
246 esis, ribosomal protein gene expression, and elevated levels of stress response genes such as the act
247 how a highly reduced quinone pool caused by elevated levels of succinate is likely responsible for t
248 MRL/lpr and NZM2410 mice accumulate markedly elevated levels of surface-bound nuclear self-antigens.
250 strongly associated with plasma leakage, and elevated levels of syndecan-1 and claudin-5 are strongly
255 sciatic nerve lesion in adult mice leads to elevated levels of Tet3 and 5-hydroxylmethylcytosine in
258 cytes are hyperactivated in vivo and secrete elevated levels of Th1 and Th2 cytokines after TCR ligat
259 icient mdx muscle, which correlates with the elevated levels of the alpha7beta1 integrin observed in
260 is well documented that aging patients with elevated levels of the amino acid metabolite homocystein
261 ice retain the remaining p73 allele, exhibit elevated levels of the antiapoptotic protein Bcl2 and th
264 own syndrome (DS) and AD, which is caused by elevated levels of the beta-cleaved carboxy-terminal fra
266 ed transgenic CGRP-sensitized mice that have elevated levels of the CGRP receptor hRAMP1 subunit in n
268 When P2-HNF4alpha-only mice (which have elevated levels of the cytokine resistin-like beta, RELM
269 revealed an association of LOXL2 action with elevated levels of the EMT regulatory transcription fact
270 clinical study of nasal secretions in which elevated levels of the human forms of these antimicrobia
272 n clinical specimens of human breast cancer, elevated levels of the mammalian paralogs MMP2, MMP9, an
274 transcript abundance changes in response to elevated levels of the plant hormone ethylene in roots f
276 overexpressed in pancreatic cancer producing elevated levels of the RON tyrosine kinase receptor prot
277 ncreased nuclear localization of YAP/TAZ and elevated levels of the target genes in the endothelium i
278 the presence of glucose that correlates with elevated levels of the toxic catabolite methylglyoxal.
281 hionine tRNA and cancer progression, whereby elevated levels of this tRNA specifically drive synthesi
282 neuroprotection via increased BBB integrity (elevated levels of tight-junction protein, Claudin 5, an
283 r-276a-binding site in the tim 3' UTR causes elevated levels of TIM and approximately 50% arrhythmici
285 risk of autoimmune disorders, accompanied by elevated levels of tissue necrosis factor (TNF) alpha.
288 iles in strains lacking Spt4 reveal globally elevated levels of transcribing RNA Polymerase II (Pol I
289 ome loss impacts core metabolism, leading to elevated levels of tricarboxylic acid cycle intermediate
291 , a class of inflammatory diseases marked by elevated levels of tumor necrosis factor (TNF)-alpha and
292 thermore, we found that ant ail6 plants have elevated levels of two defense hormones: salicylic acid
294 that produce defective CD11b associate with elevated levels of type I interferon (IFN-I) in lupus, s
298 d viral polymerase activity that resulted in elevated levels of viral transcription and virus output.
300 rminal fibroblast growth factor 23 (cFGF23), elevated levels of which are also prospectively associat
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