ライフサイエンスコーパス: help( to|) explain

1 Our results thus help to explain a range of puzzling behaviors, such as e

2 affecting putative regulatory elements might help explain additional risk of simplex autism.

3 sttranslationally modified and regulated and help explain an evolutionary pressure to retain the high

4 than neuronal cell bodies in STN, which may help explain anatomic variation in stimulation efficacy.

5 The domain architecture of a large RNA can help explain and/or predict folding, function, biogenesi

6 affinities and kinetic parameters, which may help to explain and predict Kv11.1-mediated cardiotoxici

7 This study may help explain aspects of PD pathophysiology and the mecha

8 These findings may help explain associations between arsenic exposure and c

9 lling case for how evolutionary thinking can help explain behaviours that cluster with deprivation.

10 suggest that the history of host shifts may help explain both the striking phenotypic diversity with

11 -specific regulatory circuitry of DLX5 might help explain certain aspects of preeclampsia.

12 ed to significant changes in ecosystems that help explain changes in current archaeological patterns

13 ain how ribosomopathies may provide clues to help explain Dameshek's paradox and highlight some of th

14 Thus, observing brushing performance might help to explain deficits in oral hygiene.

15 in this study, with additional analysis, may help explain diet-related differences in health outcomes

16 The binding models help explain differences in AR and GR genomic binding an

17 ndently from each other and whether they can help explain differences in CVD mortality between Easter

18 reveal subtle differences in signaling that help explain differences in drug response.

19 e differences in specific phenolic compounds help to explain differences in AC observed between varie

20 ing spontaneous excitatory activity, and may help to explain differences observed in the activity of

21 curring variation of the immune response may help to explain differential susceptibility to disease o

22 Age at first trauma could help explain discrepancies in results of past studies of

23 mic contributions to particle deposition may help to explain discrepancies between model-based expect

24 volumes of unique microenvironments that may help to explain discrepancies in deep-sea biogeochemical

25 ween lateral and basal nuclei, these results help to explain disparate findings about the effects of

26 ith triple-negative breast cancer that might help explain disparities in incidence and aggressive cha

27 emperature during particular life stages may help explain each of these ecological responses to clima

28 t favorably influence energy balance and may help explain epidemiologic associations between whole-gr

29 ces among different ethnic groups, and could help explain ethnic differences in colorectal cancer inc

30 d temporal heterogeneities of drug dosing to help explain, examine, and prove this concept.

31 rves from laboratory growth rate experiments help explain field observations of relative abundances:

32 The findings in this study can help to explain field observations in previous studies.

33 These neuroanatomical changes help explain functional phenotypes of this animal model,

34 allucinations of Parkinson's disease and can help to explain handicaps in driving capacities and dysf

35 lity of negatively charged halocomplexes may help explain Hg methylation in marine systems such as th

36 system, providing a functional link that may help explain high impulsivity in methamphetamine-depende

37 In particular, this might help explain histological patterns of grey matter connec

38 Sedimentation and eutrophication help explain historical changes in intermediate host ran

39 hemosensory afferents inside taste buds will help explain how a coherent output is formed before bein

40 The findings provide a mechanism to help explain how a strong pOFC pathway, which is poised

41 These functions could help explain how activin A modulates physiological signa

42 It can also help explain how an oncogenic mutation or SNP works.

43 Neighbourhood effects also help explain how and why the benefits of interventions v

44 Our results help explain how Arp2/3 complex is locked in an inactive

45 This mechanism might help explain how chaperones can facilitate the folding o

46 portant for hemostasis and wound healing and help explain how fibrinolysis is greatly retarded as clo

47 ct a cancer-miRNA-pathway network, which can help explain how miRNAs are involved in cancer.

48 These findings help explain how mTORC1 selects its substrates, how its

49 k between evolution and machine learning can help explain how natural selection across fluctuating en

50 These results help explain how reproduction of HSV-1, a ubiquitous, me

51 of nicotine reward-related behavior and may help explain how smokers of menthol cigarettes exhibit r

52 This may help explain how stress contributes to substance abuse a

53 Together, our findings help explain how the spatial and temporal behaviors of t

54 To help explain how these small structural differences can

55 Climate drives phenology and traits help explain how this takes place biologically.

56 becomes localized during regeneration would help explain how wounds establish pattern in new tissue.

57 These data help to explain how an enveloped virus such as NiV can i

58 These findings help to explain how chronic TLR-mediated inflammation ma

59 The features of this multiplexed mechanism help to explain how complex connectivity is encoded and

60 observed heterogeneity in origin firing and help to explain how defined replication timing profiles

61 These experiments help to explain how dogs exploit the fluid dynamics of t

62 actin nucleator Arp2/3 complex, which might help to explain how environmental signals are translated

63 These results help to explain how even short-term HS diets may impact

64 nding of the two kinds of photoreceptors and help to explain how gene duplication and the formation o

65 Here we present two mechanisms that help to explain how mutations in one VGSC gene, Scn8a, c

66 r flow rates than larger outcrops, which may help to explain how so much lithospheric heat is extract

67 The model can help to explain how success or failure of PS-mediated Fe

68 f cellular host defense responses, which may help explain HTLV-1-related pathogenesis and oncogenesis

69 These data help explain, in part, the seemingly paradoxical observa

70 Our results may also help to explain individual variation in susceptibility t

71 ures differing in severity and duration will help explain interesting properties of plasticity, such

72 lesterol on the amyloidogenicity of IAPP and help explain its debated role in type 2 diabetes mellitu

73 che space in its introduced range, which may help explain its invasiveness.

74 rpine hydrochloride on the Schlemm canal may help explain its pharmacologic mechanism of action and b

75 eripheral metabolism throughout life and may help to explain its dysregulation in diabetes.

76 pidly under oxidized conditions, which could help explain low concentrations of organics within some

77 the Precambrian, when low-seawater SO4 could help explain low seawater (87)Sr/(86)Sr.

78 tion prevalence, with less serotype III, may help to explain lower GBS disease incidence in regions s

79 s associated with inherited cancer syndromes help explain mechanisms of sporadic carcinogenesis and o

80 These suggestions may help to explain most of the major established epidemiolo

81 educed phasic responses for relevant stimuli help to explain negative symptoms and provide a unified

82 rce-limited Early Triassic environments, and help explain observed body size distributions of some di

83 bility of MYCs and JAZs by FR-enriched light help explain (on the molecular level) the long-standing

84 the authors that limited control can indeed help explain part of the difference in observed present-

85 netic variants in intron 1 could conceivably help explain past findings relating familial atypical th

86 dditional information on gastric motility to help explain patients' symptoms.

87 These findings may help explain patterns of amphibian declines driven by a

88 The findings help explain patterns of axial motoneuron recruitment an

89 Targeted approaches have been widely used to help explain physiological adaptations, but few studies

90 These data help explain pneumococcal virulence after IAV infection

91 These structural observations help to explain preexisting mutational data and provide

92 n the ON signal transmitted to the brain may help to explain preferential reports of 'bright' phosphe

93 ht and timing of synaptic drive, which would help explain premotor population shifts.

94 of the M and G proteins, respectively, which help explain previously observed differences between NiV

95 zed phosphatase is a novel activity that can help explain previously observed increases in PTP1B oxid

96 This perspective may help to explain qualitative differences and functional o

97 These associations may help to explain racial differences in US stroke rates an

98 it transitional structural features that may help explain reaction divergence.

99 droxylation was invoked over 40 years ago to help explain reactivity patterns in cytochrome P450, and

100 stance associated with the H58 haplotype may help to explain recent outbreaks of typhoid in Malawi an

101 These results will help to explain remodeling of excitation-contraction cou

102 ng the idea that using such a component will help explain reported adverse health trends as well as h

103 Our findings may help explain reported health benefits of exposure to nat

104 s, which are recognised in nephrology, could help to explain residual risk of cardiovascular events i

105 erropericlase across the spin transition can help explain seismic and mineralogical models of the low

106 This latter finding could help to explain sexual dimorphism in F0 and formants tha

107 ITAM and Jak-STAT signaling pathways and may help explain signal integration by those pathways.

108 ys for novel fatty acid production in seeds, help explain some of the current limitations to accumula

109 dentate gyrus in children with OSAS that may help explain some of the neurocognitive deficits describ

110 Our findings help explain some of the ocular surface anomalies seen i

111 These illustrations help explain some of the principal problems of health po

112 Imaging biomarkers may help explain some of this variance, as diffusion weighte

113 Our findings may help to explain some of the phenotypes of Arabidopsis pr

114 suggests that the intestinal microbiota may help to explain some of these differences in disease exp

115 The closer match in ON pathway responses may help to explain some preferential reporting of bright st

116 hydrometeor formation in climate models will help to explain sources of model diversity in cloud forc

117 e variation to land surface models (LSM) can help explain spatial patterns of mortality.

118 he biological target of the toxin which will help explain such potent neurological activity is still

119 ite strong innate and antibody immunity, may help to explain susceptibility in these individuals and

120 ability of myosin binding to actin and could help explain the acceleration of cross-bridge interactio

121 The results help explain the apparent similarities as well as some i

122 t into the filaggrin-deficient phenotype and help explain the barrier defect in patients with AD with

123 quent macrophage damage by SIV infection may help explain the basis of more rapid disease progression

124 for the antimicrobial effects of bile salts, help explain the beneficial effects of bile salt mixture

125 dings shed light on the pathogenesis of SLE, help explain the benefit of agents that target B cells a

126 These differences may help explain the benefit of palliative care involvement

127 These findings help explain the broad tropism of human cytomegalovirus

128 emical similarities among carbon sources can help explain the causes of these constraints.

129 They use this cell-based assay system to help explain the clinical manifestations of some otherwi

130 previously unknown signaling platforms that help explain the complex behavior of cannabinoids and ma

131 ession of MMP-9 and specific MMP-9 forms may help explain the constitutive vascular remodeling and in

132 These findings may help explain the counterintuitive relationship between B

133 Results from these DNA rearrangements may help explain the CTD copy number variation seen across e

134 The time scale of soil MeHg retention may help explain the decadal time lag frequently observed fo

135 persal and mutation are all factors that may help explain the decoupled biogeographic patterns for th

136 cteristics of the decatenation mechanism and help explain the differences between their activities.

137 cofactor, which are also pH-dependent, could help explain the different reactivities of the wild-type

138 homeostasis in dopaminergic neurons that may help explain the differential neuronal vulnerability obs

139 The findings of this study may help explain the difficulty of inducing beta cell prolif

140 It is suggested that these factors help explain the discrepancy between promising outlooks

141 In addition, these findings might help explain the ecological success reported for P. astr

142 partitioning of non-native proteins and may help explain the etiology of septin-linked human disease

143 Together, our results might help explain the evolution of foveated visual systems wi

144 se results are relevant for wine experts and help explain the evolution of wine at the bottling stage

145 In addition, this tradeoff can help explain the extensive phenotypic variation we obser

146 e HBV-infected Mongolian subjects, which may help explain the extraordinarily high rate of hepatocell

147 r IgLlambda becomes the dominant isotype may help explain the extreme deviations in the IgLkappa/IgLl

148 aling and cellular energy processes that may help explain the facile resistance exhibited by certain

149 ns in several distributed brain networks may help explain the following seemingly disparate symptoms

150 ility that early emerging stereotypies might help explain the foundations of the link between speech

151 MYC as a novel bona fide SPOP substrate, and help explain the frequent inactivation of SPOP in human

152 These alternate strategies help explain the health correlations of deprivation and

153 previously unrecognized role of ILC2s might help explain the heightened susceptibility of human asth

154 Follow-up studies might help explain the high frequency of ALS- or FTLD-affected

155 ductivity is a general phenomenon, which may help explain the high ionic conductivity in doped fluori

156 These results may help explain the high level of lipid oxidation in PE-con

157 These findings may help explain the historically low incidence of meningoco

158 pathways affected by SOX11-target genes may help explain the impact of SOX11 expression on patient o

159 tational changes into functional groups that help explain the impediments to the emergence of maravir

160 ivation is insufficient in vivo, it may also help explain the inconclusive results in human studies w

161 glucose tolerance, providing a mechanism to help explain the increased diabetes risk in shift worker

162 own of North Pacific climate variability can help explain the large magnitude and potentially the qui

163 part regarding optoelectronic properties and help explain the long carrier lifetime in halide perovsk

164 This newly uncovered role for AFPs may help explain the long-speculated role of AFPs in freeze-

165 These results help explain the low level of antibiotic production obse

166 eract to cause sex-specific effects that may help explain the male bias in ASD incidence.

167 ronmental factor x sex) theory of autism may help explain the male predominance.

168 persists in vulnerable individuals, it could help explain the morning peak in adverse cardiovascular

169 depression of neurotransmission we found may help explain the motor impersistence in HD patients.

170 examined for clinical information that could help explain the negative outcome.

171 To help explain the observed cleavage patterns, we also use

172 encing fitness in clonal plants and may also help explain the occurrence of genetic diversity in ster

173 Our results help explain the paradox of specificity in alloreactive

174 well as their influence on alpha7 nAChRs may help explain the pathophysiology of schizophrenia and ma

175 The results help explain the phenomenon of aggressive local tumor re

176 nvestigate how selective vulnerability could help explain the phenotypes and analysed the effect of m

177 These findings help explain the poorer prognosis of t(4;14) MM and furt

178 to and signal through alpha4beta7, which may help explain the preferential infection of gut CD4(+) T

179 These Cu uptake strategies help explain the presence and distribution of dissolved

180 th as redox buffer and complexant, which may help explain the presence of Fe(II) in oxic circumneutra

181 isms balance robustness and evolvability and help explain the prevalence of hypermutation in various

182 These results help explain the previously described vacuolar acidifica

183 nents independently of lamins A/C, which may help explain the proliferation-promoting function of LAP

184 reveal novel aspects of CSL binding that may help explain the range of binding observed in vivo.

185 These findings help explain the range of published observations of Nano

186 n(s) and patterns of paralog retention could help explain the rapid radiation and current ecological

187 This may help explain the rarity of PDAC in persons with chronic

188 lution of variable substrate specificity may help explain the reduced dermonecrotic potential of some

189 are central to host defense, these data may help explain the reduced effectiveness of glucocorticoid

190 in the development of schizophrenia and may help explain the reduced numbers of synapses in the brai

191 rom both experiments and 3D simulations, may help explain the relationship between bleeding time in v

192 Together, these observations help explain the remarkably specific genetic consequence

193 ion by miR-H2 has been a major hypothesis to help explain the repression of lytic gene expression dur

194 The findings help explain the results of the Simplirix trial.

195 t puberty, these early emerging biases might help explain the robust prosocial and financial biases m

196 The measurements described here may help explain the role of electrostatics in many other en

197 , we provide evidence that could potentially help explain the somewhat counterintuitive overexpectati

198 Our results help explain the specificity of Eco 6S RNA for Esigma(70

199 ine-containing substrate/inhibitor ENSA, can help explain the temporal sequence of events during exit

200 Our findings help explain the tremendous variation in species respons

201 the coevolutionary perspective, our work may help explain the ubiquity of small-world topologies aris

202 restrial traits in cardiac function that may help explain the unique sensitivity of some deep-diving

203 ation multiple non-covalent interactions can help explain the well-ordered complexity of many biologi

204 py (cryo-EM), reveal structural details that help explain the wide functional diversity of this ABC t

205 iety of structural and process criteria that help explain the wide outcome variations that occur acro

206 This finding could help explain the wide range of Alport syndrome onset and

207 Our results help explain the widely divergent, previously published

208 These findings help to explain the alterations in permeability and nucl

209 These help to explain the autonomous regulation of albumin and

210 in Symbiodinium cells in hospite, they could help to explain the breakdown of the coral-Symbiodinium

211 reductive and oxidative half-reactions that help to explain the broad substrate repertoire of NR.

212 Associations with blood pressure (BP) may help to explain the cardiovascular effects of air pollut

213 Our findings help to explain the cell-type-dependent virus neutraliza

214 ryonic and postembryonic cell behaviour, and help to explain the constancy of tissue architecture tha

215 A-867744, compared with TBS-516 and TQS, may help to explain the distinct functional effects of A-867

216 both typical and adverse soil conditions may help to explain the diversification and coexistence of t

217 ysterious aspects of the meiotic process and help to explain the evolutionary basis of functional ada

218 for Abl kinases in prostate cancer that may help to explain the failure of Abl kinase inhibitor imat

219 ated conformational stabilization of CTD may help to explain the functional roles of MHR not only dur

220 his favors productive ligand binding and may help to explain the generally increased functional activ

221 dwarf planets in the Kuiper belt, which may help to explain the high albedos shown by some of these

222 l determinants of raft localization may both help to explain the hysteresis of antidepressant action

223 f autonomic dysfunction that we describe may help to explain the increased cardiovascular risk in RA,

224 Nevertheless, the findings might help to explain the increased prevalence of type 2 diabe

225 This mechanism may help to explain the increased sensitivity of some stress

226 This could help to explain the inferior immunological responses to

227 We discuss how our results help to explain the large effect of the X chromosome in

228 ggested that decreased nature experience may help to explain the link between urbanization and mental

229 ion, the meiofaunal habit of Saccorhytus may help to explain the major gap between divergence times s

230 Finally, they help to explain the mechanism of action of a novel class

231 Imaging studies help to explain the mechanism of the association.

232 segregated dendritic compartments, which may help to explain the morphology of neocortical pyramidal

233 pression and function of CD300 receptors may help to explain the peculiarities and distinctness of th

234 derstanding of cutaneous HPV biology and may help to explain the potential connection between some be

235 es of schizophrenia, our findings might also help to explain the potential mechanism of emotional abn

236 olated from the convecting mantle, which may help to explain the preservation of early Hadean (>4.5 b

237 al evolution during antibiotic treatment can help to explain the processes leading to antibiotic resi

238 These findings may help to explain the protumorigenic effect of PRAS40 and

239 Our results may help to explain the rapid exchange of antibiotic resista

240 These findings help to explain the rather discrepant facts of neutropen

241 The results help to explain the regulation of metastatic cells by c-

242 Expression quantitative trait loci (eQTLs) help to explain the regulatory mechanisms underlying the

243 This organization may help to explain the role of the chromosome axes in promo

244 These findings help to explain the selective influence of RppH on bacte

245 Our data help to explain the sensory nature of the migraine aura

246 baseline respiratory tract microbiota might help to explain the so-called frequent-exacerbator pheno

247 Clinically, the findings may help to explain the therapeutic benefit of CGRP-mAb in r

248 eatment of platelet production disorders and help to explain the thrombocytopenia in patients with Be

249 Our results help to explain the trivial-to-topological transition in

250 lts provide mechanistic information that may help to explain the unexpected immunological interaction

251 on CC dimer structure provides insights that help to explain the unusual CC dimer structure and poten

252 s, and elucidates important differences that help to explain the wide range of immunologic phenotypes

253 species (e.g. burrowing/flying ability) may help explain their behavioural response to predation ris

254 integrative recombination pathways, and they help explain their regulation.

255 subpopulations by memantine and ketamine and help to explain their differential clinical effects.

256 ences in outcomes at treating facilities can help explain these age-based racial disparities in survi

257 Incorporation of stroma in the ODM will help explain these discrepancies.

258 clonal evolution models have been invoked to help explain this intratumoral heterogeneity.

259 Maternal age represents one factor that may help to explain this variability.

260 Roaming molecule reactions may help to explain unlikely chemical processes, involving d

261 and the selective pressures they impose may help to explain variability in sex-specific aging across

262 results provide a novel mechanism that could help explain variation in the structure of natural commu

263 a pathway of cholesterol excretion that may help to explain variation in the response of serum LDL-C

264 iopathic intracranial hypertension and could help explain visual impairments in astronauts exposed to

265 ffects its net costs and argue that this can help explain when and where control mechanisms are obser

266 This finding may help explain why adaptive radiation is common on oceanic

267 ion when amending soils with biochar and can help explain why biochar may enhance methane production

268 These findings help explain why CF mice are protected from infection an

269 ctivating epidermal barrier repair genes can help explain why developmental activation of the Toll, E

270 s dependence upon interaction parameters may help explain why experimental work on the temperature de

271 e value gained from the wisdom of elders can help explain why female resident killer whales and human

272 try from grain interiors to grain boundaries help explain why grain boundaries may be beneficial, det

273 These findings may help explain why high intensity sensory experiences are

274 ug efflux have not been described that might help explain why it is so broadly overexpressed in human

275 This paradigm may help explain why microvascular dysfunction is such a pow

276 These findings help explain why modes of symbiont transmission and repr

277 ressing neutrophils ex vivo and in vitro and help explain why neutrophils become easily activated aft

278 Our findings help explain why previous targeting of PKM2 in cancer ce

279 nature are inherently complex these findings help explain why sex is maintained in natural population

280 Our findings may help explain why shift work increases hypertension, infl

281 implications for microvascular flows and may help explain why the effects of physiological RBC aggreg

282 's stiffness to crystallographic orientation help explain why the existing methods of dendrite suppre

283 oncogenic KRas4B-but not by HRas or NRas-may help explain why the KRas4B isoform is especially highly

284 ese factors will be context dependent and so help explain why the pattern of bias is sometimes variab

285 between cecum and colon, a finding that may help explain why these tissues respond differently after

286 e host immune recognition by macrophages may help explain why this commensal is such a successful pat

287 This finding may help explain why, during REM sleep, we remain disconnect

288 ators conferred by their high toxicity might help to explain why calling has not yet disappeared, and

289 Taken together these findings help to explain why CNS neurons die after axotomy, stron

290 The data may also help to explain why genetic insults to alpha4 subunits a

291 ate how ACh strengthens higher cognition and help to explain why genetic insults to the alpha4 subuni

292 of mutational inactivation, our findings may help to explain why microbial interdependencies are comm

293 Here, we provide such evidence and help to explain why others failed to find it.

294 Furthermore, our data help to explain why p40 is an antagonist of IL-23 and IL

295 ed with the loss of sense of agency, and may help to explain why patients report that they do not exp

296 These data may help to explain why some P[II] RVs, such as P[6] and P[1

297 e may be reduced in aged individuals and may help to explain why the risk of injury increases with ag

298 icial role for the SASP in tissue repair and help to explain why the SASP evolved.

299 These findings might help to explain why TNF blockade improves lung function

300 transcriptional and functional analyses, may help to explain why type III strains are associated with