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1    Given the short-term nature of the observational record, it is difficult to assess the historical importance of this m
2 nteractions between fine scale fuel heterogeneity and wind, it is difficult to assess the success of thinning operations
3 lular complexity, such as the central nervous system (CNS), it is difficult to attribute microRNA changes to a particular
4 ssion(2), altered splicing(3) and gene fusions(4); however, it is difficult to attribute these to underlying genomic chan
5                                                    However, it is difficult to construct model SACs according to a genera
6 provide extensive information about these changes, although it is difficult to continuously observe changes over many day
7 een sleep disturbances and subsequent disturbances in mood, it is difficult to determine from self-reported data which sp
8                    However, with behavioral evidence alone, it is difficult to determine whether attention speeds visual
9 is associated with dramatic changes in gene expression, but it is difficult to determine which regulated genes are oncoge
10                                                  Therefore, it is difficult to develop a mathematical or artificial intel
11                                                     Because it is difficult to directly measure the wiring diagrams of ne
12                                                    However, it is difficult to discriminate one thiol from another becaus
13                                  Using traditional methods, it is difficult to disentangle modality-specific activation f
14                                                    However, it is difficult to distinguish the borderline and malignant t
15                           However, in noise-induced models, it is difficult to distinguish the effects of noise trauma fr
16 g-term negative psychological outcomes, but in such studies it is difficult to distinguish the effects of THC from those
17 role in the properties of a molecular organic material, but it is difficult to elucidate in the absence of single crystal
18                                                       While it is difficult to establish direct causal linkages to thinly
19                                                    However, it is difficult to estimate the actual benefit in the field,
20 ehavioural change during search is rarely evaluated because it is difficult to examine the actual encounter dynamics.
21 resistance, in fact, is such a common feature in fungi that it is difficult to identify species that exhibit widely diffe
22 erences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because d
23 ions influence social dynamics has remained elusive because it is difficult to identify the vocalizing animal among mice
24 re is no (or very little) genetic diversity among subjects, it is difficult to identify unique allelic variants, gene mod
25                                              On this basis, it is difficult to imagine graphene-a material composed of on
26                                                    However, it is difficult to interpret microarray data and identify str
27  Without adequate descriptions of placebo or sham controls, it is difficult to interpret results about the benefits and h
28 erimental design: due to the flexibility of complex models, it is difficult to intuitively design experiments that will e
29                                                       While it is difficult to investigate the reasons of poor functional
30                                                    However, it is difficult to isolate at will a single tautomer, as dyna
31                                                    However, it is difficult to load highly water-soluble drugs and achiev
32 ear how these different effects balance out, partly because it is difficult to observe them directly.
33 interiors, in particular, for non-crystalline samples where it is difficult to obtain conclusive results from X-ray diffr
34  of epigenetic inheritance in humans is challenging because it is difficult to obtain multigeneration cohorts, to collect
35                                  Our results highlight that it is difficult to predict feedback outcomes from phylogeny a
36 dividuals at clinical high risk for psychosis (CHR) is that it is difficult to predict their future clinical outcomes.
37  accumulation than deeper, millennial-aged peat (catotelm), it is difficult to project how much more aerobic decompositio
38                     Because LINE-1 elements are repetitive, it is difficult to quantify LINE-1 RNA at specific loci and t
39                   Additionally, in biological samples where it is difficult to quantify specific growth conditions, it be
40 ivery of pro-angiogenic factors has shown some benefit, but it is difficult to recapitulate the complex set of factors re
41                                                    However, it is difficult to recognize and identify wild Pulsatilla spe
42                                      In equilibrium models, it is difficult to reconcile the reported short transcription
43 Although feedback connections are ubiquitous in the cortex, it is difficult to see how they could deliver the error signa
44 s a graph, enabling individual tracking even in cases where it is difficult to segment animals from one another, or where
45 MS) of hand motor cortex (M1) as a model, but in this model it is difficult to separate out the relative contribution of
46       Therefore, in the absence of proto-pterosaur fossils, it is difficult to study how flight first evolved in this gro
47                Yet, because lies often remain undiscovered, it is difficult to study if some politicians are more honest
48 s not ideal for managing chronic neurodegeneration, because it is difficult to synthesize in defined sizes, may have poor
49                                                    However, it is difficult to test the relative contributions of migrato
50                    Because these properties are correlated, it is difficult to understand each property's unique contribu