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1 Given the short-term nature of the observational record, it is difficult to assess the historical importance of this m
2 nteractions between fine scale fuel heterogeneity and wind, it is difficult to assess the success of thinning operations
3 lular complexity, such as the central nervous system (CNS), it is difficult to attribute microRNA changes to a particular
4 ssion(2), altered splicing(3) and gene fusions(4); however, it is difficult to attribute these to underlying genomic chan
6 provide extensive information about these changes, although it is difficult to continuously observe changes over many day
7 een sleep disturbances and subsequent disturbances in mood, it is difficult to determine from self-reported data which sp
8 However, with behavioral evidence alone, it is difficult to determine whether attention speeds visual
9 is associated with dramatic changes in gene expression, but it is difficult to determine which regulated genes are oncoge
16 g-term negative psychological outcomes, but in such studies it is difficult to distinguish the effects of THC from those
17 role in the properties of a molecular organic material, but it is difficult to elucidate in the absence of single crystal
20 ehavioural change during search is rarely evaluated because it is difficult to examine the actual encounter dynamics.
21 resistance, in fact, is such a common feature in fungi that it is difficult to identify species that exhibit widely diffe
22 erences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because d
23 ions influence social dynamics has remained elusive because it is difficult to identify the vocalizing animal among mice
24 re is no (or very little) genetic diversity among subjects, it is difficult to identify unique allelic variants, gene mod
27 Without adequate descriptions of placebo or sham controls, it is difficult to interpret results about the benefits and h
28 erimental design: due to the flexibility of complex models, it is difficult to intuitively design experiments that will e
32 ear how these different effects balance out, partly because it is difficult to observe them directly.
33 interiors, in particular, for non-crystalline samples where it is difficult to obtain conclusive results from X-ray diffr
34 of epigenetic inheritance in humans is challenging because it is difficult to obtain multigeneration cohorts, to collect
36 dividuals at clinical high risk for psychosis (CHR) is that it is difficult to predict their future clinical outcomes.
37 accumulation than deeper, millennial-aged peat (catotelm), it is difficult to project how much more aerobic decompositio
38 Because LINE-1 elements are repetitive, it is difficult to quantify LINE-1 RNA at specific loci and t
39 Additionally, in biological samples where it is difficult to quantify specific growth conditions, it be
40 ivery of pro-angiogenic factors has shown some benefit, but it is difficult to recapitulate the complex set of factors re
43 Although feedback connections are ubiquitous in the cortex, it is difficult to see how they could deliver the error signa
44 s a graph, enabling individual tracking even in cases where it is difficult to segment animals from one another, or where
45 MS) of hand motor cortex (M1) as a model, but in this model it is difficult to separate out the relative contribution of
46 Therefore, in the absence of proto-pterosaur fossils, it is difficult to study how flight first evolved in this gro
47 Yet, because lies often remain undiscovered, it is difficult to study if some politicians are more honest
48 s not ideal for managing chronic neurodegeneration, because it is difficult to synthesize in defined sizes, may have poor
50 Because these properties are correlated, it is difficult to understand each property's unique contribu