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1 tions of electric vehicles (EVs) deployment, it is important to account for emissions from electricit
3 ome in research and clinical settings, where it is important to adhere to strict timing, or where acu
5 Given that such environments arise naturally it is important to ask whether they can instead be turne
9 on to experimentally determined coordinates, it is important to assess the reliability of using predi
13 ptor really depends on its protein sequence, it is important to be able to predict this probability o
19 athogenesis of EIP has yet to be determined, it is important to bring awareness to this unique diseas
20 the functional nature of a set of proteins, it is important to capture the function of the proteins
21 nt effects on seabird populations elsewhere, it is important to carry out further work to determine w
25 c pain, and autism spectrum disorders; thus, it is important to characterize the mechanisms regulatin
26 d modulate the limb-moving lumbar circuitry, it is important to clarify the functional organization o
27 ated increase in extracellular fluid volume, it is important to confirm whether haematocrit increase
28 mpact on placebo-response and drug-response, it is important to consider also the specific factors in
29 re is likely to occur in practice, and thus, it is important to consider an imputation model that acc
31 ict how species loss will affect ecosystems, it is important to consider how biodiversity influences
32 to diagnostic timing and provision of care, it is important to consider Kawasaki Disease in older de
36 ting compounds that induce oxidative stress, it is important to consider the contribution of NKA inhi
37 Thus, to reduce foodborne viral infections, it is important to consider the differences in virus' re
38 rforming QoL or cost-effectiveness analyses, it is important to consider the expected outcomes (e.g.,
39 ficial to some patients with mood disorders, it is important to consider the limitations of the avail
40 ces of evidence from many different sources, it is important to consider the role of data uncertainty
43 discrepant estimates of AMR-related deaths, it is important to consider which method was used and wh
45 entity and difficult to diagnose reason why it is important to continue with clinical investigations
46 n-transmitted campylobacteriosis in mice and it is important to control the elevation of C. jejuni vi
48 ate a population's salt intake distribution, it is important to correct 24-h urinary sodium excretion
50 riven gain-of-function (GOF) mutants of p53, it is important to define a common mechanism to systemat
51 e KPD programs were not designed to help CP, it is important to define allocation metrics that enable
53 e cohort with known metabolic abnormalities, it is important to derive one's own equations based on m
54 r and organismal consequences of aneuploidy, it is important to determine how altered gene doses impa
55 n or dye-sensitized solar cells), and hence, it is important to determine if cadmium-sulfur moieties
58 o make inferences about cognitive processes, it is important to determine the "spatial spread" of ECo
60 mount of Ca(2+) entering during stimulation, it is important to determine the level of the ion close
63 fying PPIs are time-consuming and expensive, it is important to develop automated computational metho
67 tion of added ingredients is difficult, thus it is important to develop rapid techniques for quantifi
73 advance the rational design of CF therapies, it is important to elucidate how mutational defects in C
76 and the small number of studies identified, it is important to ensure established analysis methods a
78 dministrative and resourcing challenges, but it is important to ensuring the robustness of the analys
80 luded in earlier phase studies, and for whom it is important to establish an appropriate standard of
85 many aspects of quantum information science, it is important to establish this phenomenon in molecula
86 variation in human NMNAT2 mRNA expression so it is important to establish whether reduced levels of N
87 As ecosystems progress through recovery, it is important to estimate any resulting deficit in bio
88 genes generate diverse functional products, it is important to evaluate expression at the isoform le
90 ping these changes are evolving quickly, and it is important to evaluate how useful these techniques
92 me imminent, and if programs are to succeed, it is important to evaluate the WHO programmatic guideli
93 disorders such as Parkinson's disease (PD), it is important to examine how AgNPs affect microglial i
94 on's roles, responsibilities, and authority, it is important to examine how the position is perceived
96 f how these proteins mediate 30S maturation, it is important to expand on studies of 30S assembly int
98 ariety of pesticides throughout development, it is important to explore temporal patterns of coexposu
109 pped lineshapes that are typically observed, it is important to go beyond a single-configuration repr
112 geneity of frailty in clinical presentation, it is important to have effective strategies for the del
113 Since the whisker system is a popular model, it is important to have methods for measuring whisker mo
114 gy becomes increasingly used in biomedicine, it is important to have techniques by which to examine t
119 of stroke in people with migraine with aura, it is important to identify and modify any vascular risk
123 the discovery of candidate therapeutics, and it is important to identify markers of disease activity
124 ORTANCE MERS-CoV has pandemic potential, and it is important to identify mutations in viral proteins
126 Therefore, as in other ecological systems, it is important to identify quantitative relationships d
132 directly benefit thermoelectric performance it is important to identify the role of featured topolog
133 usual complication of vitreoretinal surgery, it is important to identify this condition promptly and
141 recapitulate the in vivo oxygen environment, it is important to integrate systems for monitoring and
142 ral based gene therapy is under development, it is important to investigate alternative approaches to
143 rder to use F(E) NO as a reliable biomarker, it is important to investigate factors that influence F(
144 teran population is a special population and it is important to investigate how PTSD in the veteran p
145 ure biomonitoring studies and emphasize that it is important to investigate the biotransformation pat
146 and their impact on mitochondrial function, it is important to investigate the mechanisms that regul
151 mechanical forces affect neuronal outgrowth, it is important to investigate whether mechanosensitive
153 cess or down-line handling of this compound, it is important to know and understand the relationship
155 f a rock by injection of low salinity water, it is important to know i) how the injected low salinity
159 adults, who are less technology experienced, it is important to know whether they are willing to use
160 iesel engines with low environmental impact, it is important to link health and climate-relevant soot
161 y interacts with E-cadherin, indicating that it is important to maintain epithelial integrity beyond
162 as a biomarker of mitochondrial dysfunction, it is important to measure both cellular and cf mtDNA.
163 acellular metabolites in cellular processes, it is important to measure the dynamics and fluxes of sm
171 ally had lower concentrations of pesticides, it is important to note that in comparison with NHANES p
178 assumption." In evaluating this assumption, it is important to note that the outcome is to be relati
179 s do project to image-forming brain targets, it is important to note that this is only the first step
180 anding for infectious recurrent pharyngitis, it is important to note that we should consider PFAPA sy
185 critical role in their function; therefore, it is important to our understanding of their function t
186 h this interpretation is not new, we believe it is important to present this framework in light of re
189 ly control, transport behavior under strain, it is important to quantify the effects of strain on the
190 l agents of aphid crop pests [11], and thus, it is important to quantify the scale of their migration
191 space solid-phase microextraction (HS-SPME), it is important to reach the highest level of reproducib
196 remain, in the quest for viral eradication, it is important to recognize that a significant, dynamic
197 those at greater risk of atrophy developing, it is important to recognize that adequately treating ex
198 community adapts to new working conditions, it is important to recognize that some of our actions ma
200 ociated with forest resiliency, finding that it is important to reduce the uncertainty in both of the
201 k between Rett syndrome and MECP2 mutations, it is important to reflect on the tremendous advances in
205 mes more widely used in biomedical research, it is important to revisit existing data analysis paradi
207 r investigating the two pathways of reading, it is important to stimulate each pathway per session su
210 prove the stability qualities of wholegrain, it is important to study lipid stability of wheat variet
212 ted contacts in folding proteins accurately, it is important to study the challenges of reconstructin
213 ng method for childhood lung sound analyses, it is important to study the effect of airflow on the pa
215 nitive hallmark of Alzheimer's disease (AD), it is important to study whether synaptic circuits invol
216 ity is unknown for many enteropathogens, but it is important to support the development of enteric va
225 s across different subcellular compartments, it is important to understand how ERK activity is tempor
228 and how mDA neurons perform these functions, it is important to understand how mDA-specific genes are
231 To reduce social inequalities in mortality, it is important to understand how specific causes of dea
232 set by the position of the anaphase spindle, it is important to understand how spindles become orient
235 s that are often subjected to control, thus, it is important to understand how the reduction of this
237 e mechanism of neurotransmitter release, but it is important to understand how these assays report on
239 es are thought to influence gene regulation, it is important to understand how they are re-establishe
240 soil microbes are primarily carbon limited, it is important to understand how they respond to increa
243 high levels of morbidity and can be lethal, it is important to understand how Toxoplasma traffics to
247 ntibodies necessary for clinical protection, it is important to understand regional patterns of antib
252 or defense against the virus, and therefore, it is important to understand the complex interactions b
254 somatic and germline patterns of variation, it is important to understand the details and exceptions
255 stroke is the most common subtype of stroke, it is important to understand the development of ALI fol
256 cellular homeostasis under oxidative stress, it is important to understand the effect of oxidants on
257 le of Th17 cells in autoimmune pathogenesis, it is important to understand the factors that control T
258 ams is complex and time-consuming, therefore it is important to understand the factors that may hinde
263 this technology continues to evolve rapidly, it is important to understand the indications and contra
265 een developed in women of European ancestry, it is important to understand the limitations of their p
266 f pregnant women are prescribed antibiotics, it is important to understand the mechanisms contributin
268 MR1 and the high prevalence of human MR1Ts, it is important to understand the mechanisms of MR1-depe
272 n order to develop novel drugs and vaccines, it is important to understand the molecular mechanisms t
273 in synthesis and other areas of science, and it is important to understand the nature of the thin fil
275 od is also a time of rapid brain growth, and it is important to understand the potential neurobehavio
278 ll effective vaccines and treatments emerge, it is important to understand the scientific rationale o
280 ion of statistical methods to rare variants, it is important to understand the strengths and limitati
281 o design these advanced bioink formulations, it is important to understand the structure-property-fun
282 ancial conflicts of interest in health care, it is important to understand the types and distribution
284 ing developed and used in clinical practice, it is important to understand their long-term metabolic
292 to the grave risks and complications of FT, it is important to understand whether the psychological
293 in females during their reproductive years, it is important to understand whether the reduction in u
295 fluence public opinion on climate change, so it is important to understand whose perspectives are mos
296 iven the policy applications of this result, it is important to update the scientific record regardin
297 four members contain p40 in different forms, it is important to use a specific monoclonal antibody (m
300 quare meter at the Earth's surface, however, it is important to utilize these incident photons as eff