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1 beyond its role in regulating OT secretion, it is not known whether a deficit in CD38 expression lea
2 f cardiovascular disease at the adult stage, it is not known whether a difference in doxorubicin-rela
6 ite a long tradition of perception research, it is not known whether access to consciousness is requi
10 iome has been the subject of recent studies, it is not known whether alterations among commensal micr
18 neurotoxicity in Alzheimer disease (AD), but it is not known whether anti-Abeta antibodies are capabl
21 hibit the induction of IFN by IRF3; however, it is not known whether any RRV vIRFs inhibit ISG induct
27 are transported along the secretory pathway, it is not known whether BACE1 and APP share the same pos
28 in aged rodents has been poorly studied, and it is not known whether beneficial mechanisms evidenced
30 ficient to decrease cell viability; however, it is not known whether blocking lipogenesis in vivo can
31 vity following noxious skin stimulation, but it is not known whether brain processing of nociceptive
33 r risk of developing schizophrenia; however, it is not known whether C4 plays a causative role in thi
34 isms of p300 acetyltransferase activity, but it is not known whether CBP activity is controlled simil
46 alters metabolism in the adult and fetus but it is not known whether cortisol in the pregnant mother
47 2 are generated at the site of inflammation, it is not known whether crosstalk exists between these 2
49 d is essential for virus infection; however, it is not known whether D2 is also important for infecti
50 tivation of G protein-coupled receptors, but it is not known whether DAG modulates TRPV1 during desen
51 ds as the main sources of carbon and energy, it is not known whether de novo synthesis of amino acids
53 entrosomes are connected via MTs in mitosis, it is not known whether defects in either one of the two
55 y terminals have not been characterized, and it is not known whether developmental plasticity compens
64 ately documented across a number of species, it is not known whether each response occurs together wi
71 vents are crucibles for rapid evolution, but it is not known whether evolutionary changes arise mainl
73 ith cardiovascular and respiratory diseases, it is not known whether exposure to contemporary air pol
78 the actin-binding protein filamin A (FLNA); it is not known whether FLNA binds to WHIM CXCR4 mutants
80 clusive ligands for signaling through IFNLR, it is not known whether genetic ablation of these cytoki
81 hanges in fluid shear stress (FSS); however, it is not known whether GFR modulates PT endocytosis to
83 is well established for some drugs of abuse, it is not known whether glutamate receptors within the m
85 ing is highly specialized rhythmic behavior, it is not known whether high-conductance states and irre
88 miRNA are known to inhibit specific viruses, it is not known whether host-directed microRNAs, downstr
97 nerable to antibody neutralization; however, it is not known whether infection established by the maj
100 ated by tissue-intrinsic contractility(5,6), it is not known whether interactions between the tissue
102 hough associated with chronic HIV-1 control, it is not known whether interleukin-21 (IL-21) contribut
104 an animal model of human visual processing, it is not known whether invariant visual object recognit
105 e gamma-tubulin complex remains elusive, and it is not known whether it also regulates assembly of th
106 It has antiinflammatory effects; however, it is not known whether it can affect a biologic pathway
107 nophen causes oxidative injury in the liver, it is not known whether it causes oxidative stress in th
108 eight is a known risk factor for asthma, but it is not known whether it might also increase asthma ri
109 aling regulates multiple steps in oogenesis, it is not known whether it regulates Drosophila ovulatio
110 uitment remains mechanistically unclear, and it is not known whether kinetochore proteins other than
113 ity of P4-ATPases has not been explored, and it is not known whether lipid transfer between membrane
117 mor burden in murine models of CRC; however, it is not known whether LRH-1 is required for tumorigene
118 erstanding these various macrophage subsets, it is not known whether macrophages of one activation st
119 plicated in increased susceptibility to NTS, it is not known whether malaria affects resistance to in
121 sary for some of the responses to SSRIs, but it is not known whether mature dentate gyrus granule cel
123 bilities is currently lacking; specifically, it is not known whether metabolic redundancy will foster
124 metabolic syndrome (MetS) appear heritable, it is not known whether MetS severity as assessed by a c
125 s by specializing on particular species, but it is not known whether microbes that specialize within
127 volumes are often elevated in athletes, but it is not known whether moderate physical activity is al
128 corresponding neural correlates in monkeys, it is not known whether monkeys distort probability in a
131 y" to describe short-term memory in animals, it is not known whether multiple, independent memory sys
132 m from sequestering RNA polymerase; however, it is not known whether MvaT and MvaU function similarly
133 nvironmental fate of these new products, and it is not known whether nanoformulations can be evaluate
136 esidents of disadvantaged neighborhoods, but it is not known whether neighborhood inequalities are sp
139 n has not been examined in the GI tract, and it is not known whether Neurod1 can similarly switch cel
140 r, given potential alternative explanations, it is not known whether neuronal inhibition is in fact n
143 with physiological cardiac growth; however, it is not known whether or how physical activity-induced
145 Although inflammation promotes fibrogenesis, it is not known whether other events, such as hepatocyte
148 similar beta-sheet secondary structures, but it is not known whether pancreatic amylin affects amyloi
150 luenced by metabolite levels in culture, but it is not known whether physiological variations in meta
152 for negative compared with positive events, it is not known whether post-encoding increases in amygd
153 ERCA2) contributes to septic cardiomyopathy, it is not known whether prevention of the down-regulatio
154 orted to allosterically activate the lipase, it is not known whether Rap1A has the same ability or wh
159 drocytes from resident progenitors; however, it is not known whether regeneration restores the comple
161 t neuronal subtypes can differ [13, 14], but it is not known whether regulation of myelination by act
167 n pulmonary arterial hypertension (PAH), but it is not known whether sex hormones are risk factors fo
169 rectly on axons to regulate their outgrowth, it is not known whether signals transduced in dendrites
171 ls of the myoblast lineage secrete exosomes, it is not known whether skeletal muscle fibers (myofiber
176 e and objective sleep disturbances; however, it is not known whether stress disrupts sleep and releva
177 silence activates the auditory cortices, but it is not known whether such activation reflects immedia
178 ted superconductors has been suggested(1-7), it is not known whether such inhomogeneities-if they exi
183 -translational modification SUMOylation, but it is not known whether SUMOylation is required for func
184 segregation at high-symmetry boundaries, but it is not known whether superstructures exist at general
185 se delta (Pol delta) initiates BIR; however, it is not known whether synthesis of the invading strand
187 s polymerase-associated factor 1 (Paf1), but it is not known whether TEFs have gene-specific function
188 of grass that flower at different times, but it is not known whether temporal turnover in species com
193 d an advantage for highly trained musicians, it is not known whether the benefits measured in laborat
194 le and prevents apoptosis of host cells, but it is not known whether the cell cycle phases influence
196 perceptual interpretation of sensory inputs, it is not known whether the combination of sensory and m
198 l or multiple metals from the cytoplasm, and it is not known whether the CTD takes an active regulato
199 eural activity in oculomotor brain circuits, it is not known whether the decision-related activity in
203 channels, and while it is highly conserved, it is not known whether the functional role of this spli
209 en regeneration by CNS axons is facilitated, it is not known whether the intra-axonal content of tran
210 PTEN has been described by multiple groups, it is not known whether the loss of INPP4B affects AR ac
213 is going to get much bigger, very soon, but it is not known whether the needs of genomics will excee
216 mation relies on the same neural system, but it is not known whether the organisational principles go
220 can intervenes in the symbiotic process, and it is not known whether the plant lysin-motif receptor-l
221 ereotyped song that is stable for years, but it is not known whether the precise neural patterns unde
227 mponents, however, is poorly understood, and it is not known whether the static component requires th
228 s associated with impaired memory formation, it is not known whether the synaptic underpinnings of me
231 ium during branching morphogenesis; however, it is not known whether the vasculature has instructive
234 rks have primarily been studied in mice, and it is not known whether there are species- or clade-spec
239 se transporters and glycolytic enzymes(3-5), it is not known whether there is direct regulation of me
241 adjacent to the face-selective patches, but it is not known whether these body-selective patches for
244 eriences represent separable cell types, and it is not known whether these differentially active cell
245 some treatment-resistant patients; however, it is not known whether these effects are independent, o
248 re more active than homodimers in vitro, but it is not known whether these heterodimers signal in viv
249 of pruritus are not yet fully understood and it is not known whether these mechanisms diverge between
250 eurons in the inferior temporal (IT) cortex, it is not known whether these neurons respond differenti
251 and temporal code for spatial position, but it is not known whether these oscillations mediate simul
255 ions at early stages of cortical processing, it is not known whether these representations include mi
256 and cleavage capability of mesotrypsin, but it is not known whether these residues fully account for
257 dilate in response to surprising events, but it is not known whether these responses are primarily st
263 hare common ligands and signalling pathways, it is not known whether they act in concert to drive pat
264 eplication by inducing G-to-A hypermutation, it is not known whether they are copackaged and whether
265 from LC neurons can exert analgesic actions, it is not known whether they can act independently of as
266 ll migration and cell-cell adhesion; however it is not known whether they control formation of vessel
267 ins regulate the same developmental process, it is not known whether they function in the same molecu
268 e been reported during anaesthesia(2-7), but it is not known whether they have a role during waking p
269 cy decisions; however, many models exist and it is not known whether they produce consistent predicti
272 ciated with higher type 2 diabetes risk, but it is not known whether this association is causal.
273 functions in human cell differentiation, but it is not known whether this class of introns has a simi
274 i are correlated with many muscle disorders, it is not known whether this common phenotype is the res
276 tion and motility of the kinesin-5, Eg5, but it is not known whether this domain regulates kinesin-12
278 binoids inhibit GABA release in the RVM, but it is not known whether this effect persists in chronic
279 ng goal-directed actions and their outcomes, it is not known whether this function is localized withi
280 h different intracellular localizations, but it is not known whether this heterogeneity of viral anti
286 India originate from a recent common source, it is not known whether this is the case for populations
287 unction (TJ) complex protein expression, but it is not known whether this mechanism is utilized in es
289 is indispensable for cell survival; however, it is not known whether this pathway functions in the pr
290 n zebrafish embryos and in mouse cell lines, it is not known whether this phenomenon is observed acro
291 ough coordination with the cytoskeleton, but it is not known whether this response impacts adhesion f
293 died in the context of other drugs of abuse, it is not known whether toluene exposure differentially
296 Exercise reduces insulin resistance, but it is not known whether TRPC1 is involved in exercise-in
297 with global two-dimensional simulations, but it is not known whether turbulence driven by this instab