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2 ERAD pathways each are well-understood, very little is known about any direct cross-talk between them
4 e disorder (AUD) in patients with cirrhosis, little is known about AUD treatment patterns and their i
5 pathways, including fat oxidation; however, little is known about cafestol's effects on fatty acid m
7 f the highest expression levels of CB1R, but little is known about CB1R in the developing cerebellum.
8 th viral control during HIV-1 infection, but little is known about CD8 cross-reactivity in the contex
11 red with intra-aortic balloon pumps (IABPs), little is known about clinical outcomes associated with
17 ell activation has been extensively studied, little is known about epigenetic regulation of these pro
20 US are performed in outpatient settings, yet little is known about facility-level variation in short-
25 SIVH admissions to the US over recent years, little is known about health conditions in SIV children.
27 continuous clearing of cellular debris, but little is known about homeostatic mechanisms in the TM e
29 ce of antibiotic resistance in bacteria, but little is known about how antibiotics affect within-host
30 ies examining AVT in male fishes, relatively little is known about how AVT expression varies with fem
33 mediating the ability of ungulates to surf, little is known about how drought shapes the green wave
34 has never been measured in live retina, and little is known about how ECS alpha varies following phy
36 set of vemurafenib-resistant melanomas, but little is known about how EGFR, or possibly other recept
40 hair cell mechanotransduction channels, but little is known about how force is sensed by TMC channel
44 d states are formed by phase separation, yet little is known about how material properties are encode
50 quester C for climate change mitigation, yet little is known about how reactive Fe and Al minerals af
59 y and display regional specificity; however, little is known about how these communities differ with
61 ased susceptibility to antibiotics; however, little is known about how these mutations influence bact
63 ors to ecosystem functioning, but relatively little is known about how they respond to extreme storm
64 and DNA-damage-inducible) gene family, very little is known about how this family regulates activity
65 icated in stress-induced susceptibility, but little is known about how this pathway might encode futu
66 ptional condensates for gene expression, but little is known about how this process is controlled.
67 al hepatitis C incidence by 80% by 2030, but little is known about how this reduction could be achiev
69 the model species Arabidopsis thaliana, but little is known about how transcriptional dynamics chang
70 al membrane to the extracellular matrix, but little is known about integrin's regulators in the glia.
73 rs resistant to many conventional therapies, little is known about its influence on VDA activity.
76 ies available for SD-associated itch because little is known about its pathophysiological mechanism.
77 lutionary conservation of CK1 in eukaryotes, little is known about its regulation and the factors tha
78 pathogenesis of acute cardiac injuries, but little is known about its role in chronic cardiac dysfun
79 omeostasis and colorectal cancer, relatively little is known about its role in colon formation during
80 ies of cell fate focus on specification, but little is known about maintenance of the differentiated
81 4-S) has been studied more extensively, very little is known about mechanisms of regulation or signal
89 ferences during chronic HIV-1 infection, but little is known about sex differences in the acute phase
91 erate OE cells ceases.SIGNIFICANCE STATEMENT Little is known about signals that activate dormant stem
93 ogenesis has been largely clarified, whereas little is known about somatic mutations in noncoding DNA
97 naptic changes after social stress, although little is known about stress-induced inhibitory synaptic
106 tant response to salt stress, but relatively little is known about the biological importance of speci
115 D incidence compared with non-Hispanics, but little is known about the CKD incidence in this populati
119 l-penetrating peptides (CPPs); however, very little is known about the design of CPPs for efficient t
123 have been limited to single populations, and little is known about the dynamics of inbreeding depress
124 tcomes following surgery have been examined, little is known about the effect of a patient's communit
127 n bind to TARPs with variable stoichiometry, little is known about the effect that this stoichiometry
129 ures contribute to reduced fetal growth, but little is known about the effects of complex metal mixtu
140 ulation and in several cancers, surprisingly little is known about the function or structure of MiDAC
144 opean ancestry remain understudied, and thus little is known about the genetic architecture of phenot
148 er (CRC) cases have familial aggregation but little is known about the genetic factors that contribut
149 e pathogenesis of multiple sclerosis(2), but little is known about the heterogeneity of astrocytes an
150 involvement of the animal's microbiome, but little is known about the host's actual role and if it b
153 llergy is a growing public concern; however, little is known about the immunological mechanism(s) tha
156 the pathogenesis of complex human diseases, little is known about the impact of host genetics on sal
157 Although microbes influence plant growth, little is known about the impact of microbial diversity
159 at these molecules are harmful for patients, little is known about the impact of such antileishmanial
160 s based on their whole-genome sequences, but little is known about the impact of this diversity on th
166 trated in MFS patients and mouse models, but little is known about the intrinsic effect on the cardio
167 nsights into the viral infection cycle, very little is known about the location and folding stability
170 ncentrations in avascular peritoneal tumors, little is known about the mechanism of nanoparticle accu
173 nificant role in medication error reporting, little is known about the mechanisms by which these cult
174 ding, rehydration, and pathogen invasion-but little is known about the mechanisms by which this occur
175 xic to most aquatic nontarget organisms, but little is known about the mechanisms causing some specie
176 e assembled into multiprotein complexes, but little is known about the mechanisms required for assemb
179 ntly to chemical fluxes in the deep sea, yet little is known about the microbial communities inhabiti
182 can lead to neuropsychiatric disorders, yet little is known about the molecular basis underlying inh
188 damage to the liver and the adrenal glands, little is known about the molecular signatures of injury
189 ntaining NPCs during kidney development, but little is known about the molecule(s) regulating FGF sig
190 ation and cognitive and emotional tasks, but little is known about the morphological and molecular di
196 pite this influential theoretical framework, little is known about the neural basis of this predictiv
197 accumbens in motivated performance, but very little is known about the neurochemical underpinnings of
200 hile SLF is a significant pest of vineyards, little is known about the pest in grape agroecosystems i
202 Blob 2.0 peaked in the summer, a season when little is known about the physical drivers of such event
206 ole in homeostasis, regeneration and cancer, little is known about the post-translational regulation
207 portance for neural circuit function, only a little is known about the postnatal development of dendr
209 an lead to profound changes in behavior, but little is known about the precise molecular mechanisms t
210 lciparum, a unicellular eukaryotic pathogen, little is known about the predominant cytosine modificat
214 key for reproductive success, but relatively little is known about the processes that determine the t
215 tive and negative disease outcomes in TB but little is known about the processes that initiate fibros
216 used on overexpressed iRhom1 and -2, so only little is known about the properties of the endogenous p
220 nds on retino-centered reference frames, but little is known about the reference frames that code the
221 lex is essential to the parasitic lifestyle, little is known about the regulation of apical complex b
222 own deleterious impacts on human health, but little is known about the relationship between drought a
225 common in temporal lobe epilepsy (TLE), but little is known about the relationship of hippocampal mo
226 otal arsenic in particulate matter (PM), but little is known about the relative contribution of each
227 sex-osteology, genomics, or proteomics, but little is known about the relative reliability of these
228 diction folklore ("chasing the first high"), little is known about the relevance of cognitive process
229 of stress responses between individuals, but little is known about the relevant synaptic changes asso
231 dependence and smoking-related diseases, but little is known about the role for alpha3-containing (al
233 flow and pressure during exercise in health, little is known about the role of ET-1 in the cardiovasc
235 of dark exposure in adult animals, but still little is known about the role of interneurons and plast
237 nly on differential microbial abundance, and little is known about the role of microbial interactions
238 h has been studied in axial skeletal joints, little is known about the role of Notch in TMJ developme
239 hizosphere harbors a complex microbiome, but little is known about the role of phages in this ecosyst
241 re frequently disrupted in human tumours and little is known about the role of SASH1 in the pathogene
243 er malignancies (e.g. renal cell carcinoma), little is known about the role of this variant in specif
245 nous compounds such as amino acids; however, little is known about the role(s) of nitrogen (N) compou
247 ble improvements in diagnosis and treatment, little is known about the short-term and long-term progn
250 taining baked milk, for example muffins, yet little is known about the specific allergen content of m
251 l large T antigen (TAg), and malignancy, yet little is known about the specific integration mechanism
252 mportant element in HIT etiology, relatively little is known about the specific molecular mechanism o
256 malian glycosyltransferase family, GT31, but little is known about the structure, substrate recogniti
258 ever, the world major crops are monocots and little is known about the transcriptional programs under
260 gh MCC has a high propensity for metastasis, little is known about the underlying mechanisms that dri
261 nsiveness to extracellular stimuli, although little is known about the underlying mechanisms that gov
262 toxins hijack important immune molecules but little is known about the underlying molecular mechanism
263 approach to promote learning and memory, yet little is known about the underlying neural transfer mec
264 access is an option for these patients, but little is known about the utility of this approach to fa
265 nd on the gut microbiota-are chronic(4), and little is known about their BCR repertoires or patterns
271 their orthosteric agonist peptides, however, little is known about their extracellular domain (ECD) c
272 ogaster and some other Dipteran species, but little is known about their function in hemimetabolous i
273 velopment have been extensively studied, yet little is known about their functions during larval deve
274 s are common across various microbiomes, but little is known about their genetic inventories or poten
277 a role in periodontitis, although, to date, little is known about their interaction with the vascula
279 rovide many nutrients to the human diet, but little is known about their mineral elements composition
282 se activity in cholesterol biosynthesis, yet little is known about their post-translational regulatio
283 s) are enriched in the mammalian brain, very little is known about their potential involvement in bra
284 Ps have been associated with human diseases, little is known about their role during development.
285 -1 and DCC is maintained in the adult brain, little is known about their role in mature neurons.
286 polarity have been studied extensively, but little is known about their roles in the cell polarity o
287 tudies revealed their complex social skills, little is known about their social behaviour in the wild
291 f structural and anatomical traits; however, little is known about traits affecting g(m) in C(4) spec
294 al fluctuations in brain state, surprisingly little is known about whether and how seizures vary in t
298 Tissue regeneration declines with ageing but little is known about whether this arises from changes i