ライフサイエンスコーパス: play a critical role in

1 serted portions of the hemagglutinin protein play a critical role in achieving fusion.

2 opercularis IFG, PMv and IPL, each of which plays a critical role in action perception and execution

3 step concerted process, with the nucleophile playing a critical role in activating the olefin for con

4 Thyroid hormone signaling plays a critical role in activating M-opsin and repressi

5 en menin and mixed lineage leukemia 1 (MLL1) plays a critical role in acute leukemias with translocat

6 Epigenetic mechanisms have been shown to play a critical role in adaptive and maladaptive process

7 CD8(+) T cells play a critical role in adaptive immunity, differentiati

8 B lymphocytes play a critical role in adaptive immunity.

9 induction of C/EBPbeta and C/EBPdelta, PAGR1 plays a critical role in adipogenesis.

10 Noninvasive molecularly targeted imaging may play a critical role in aiding visualization and underst

11 The innate immune system plays a critical role in allograft rejection.

12 growth factor and pro-inflammatory cytokine, plays a critical role in alveolar macrophage homeostasis

13 Beta-amyloid (Abeta) is thought to play a critical role in Alzheimer's disease (AD), and ap

14 that the dysregulation of neuronal iron may play a critical role in Alzheimer's disease.

15 phosphoinositide 3-kinase (PI3K)/Akt, which plays a critical role in angiogenesis.

16 hese water-conducting specialized cells have played a critical role in angiosperm evolution; they det

17 Sound localization plays a critical role in animal survival.

18 Lymphocytes play a critical role in antitumor immune responses.

19 the "arm" region that studies have shown to play a critical role in assembly.

20 Smooth muscle cells (SMC) play a critical role in atherosclerosis.

21 ical locus ceruleus (LC) activity, as the LC plays a critical role in attentional modulation.

22 e adult somatic cell homeostasis in vivo, it plays a critical role in B-cell lymphomagenesis.

23 E STATEMENT Dopamine signals in the striatum play a critical role in basal ganglia function, such as

24 1A mutant suggest that H2AX ADP-ribosylation plays a critical role in base excision repair (BER).

25 is unclear despite that soil microorganisms play a critical role in biogeochemical cycling.

26 Tumor associated macrophages (TAMs) play a critical role in biology of various cancers, incl

27 The reduced partial pressure of oxygen plays a critical role in boosting battery lifespan.

28 t between the ligand and cobalt in Co(II)CPY plays a critical role in boosting its activity.

29 tudy provides in vivo evidence that RAD51AP1 plays a critical role in breast cancer growth and metast

30 tion studies provided evidence that Rad51ap1 plays a critical role in breast cancer stem cell (BCSC)

31 y, our work establishes that the Tat pathway plays a critical role in Brucella virulence.

32 Vitamin D plays a critical role in calcium homeostasis and in the

33 Breast cancer stem cells (BCSCs) play a critical role in cancer recurrence and metastasis

34 Dysregulated Wnt/beta-catenin activation plays a critical role in cancer progression, metastasis,

35 g evidence indicates that the nervous system plays a critical role in cancer progression.

36 Tissue stiffening plays a critical role in cancer progression.

37 s biosynthesis, we showed that this molecule plays a critical role in capsule biosynthesis and mainta

38 Direct air capture (DAC) is positioned to play a critical role in carbon removal, yet remains unde

39 Magnesium ions play a critical role in catalysis by many enzymes and co

40 zed by two invariant histidine residues that play a critical role in catalytic activity.

41 MAF1 is a phosphoprotein that plays a critical role in cell growth control as the cent

42 aments into distinct cytoskeletal structures plays a critical role in cell physiology, but how protei

43 Multisite protein phosphorylation plays a critical role in cell regulation [1-3].

44 II collagen) is a hemidesmosomal protein and plays a critical role in cell-cell matrix adhesion in th

45 Voltage-gated sodium channels play a critical role in cellular excitability, amplifyin

46 Medullary thymic epithelial cells (mTECs) play a critical role in central immune tolerance by medi

47 ngeal anastomoses or pial collateral vessels play a critical role in cerebral blood flow (CBF) restor

48 Since the intrauterine milieu plays a critical role in childhood growth, we explored t

49 ity recorded over frontotemporal MEG sensors plays a critical role in choice option integration.SIGNI

50 Microglia and macrophages play a critical role in choroidal neovascularization (CN

51 olecule conferred by the extended linker can play a critical role in circumventing this unproductive

52 h Arp2/3 complex-dependent actin nucleation, plays a critical role in CNS myelination, and its absenc

53 tone H3 glutamine 5 dopaminylation (H3Q5dop) plays a critical role in cocaine-induced transcriptional

54 een the thalamus and prefrontal cortex (PFC) play a critical role in cognitive function and arousal.

55 cent findings reveal that VAN signaling also plays a critical role in cognitive processes, including

56 WNT/beta-catenin (CTNNB1) signaling pathway plays a critical role in colorectal carcinogenesis.

57 Freeze-thaw cycle dynamics play a critical role in controlling cold season CO(2) an

58 T regulatory cells (Tregs) play a critical role in controlling the immune response,

59 Molecular orientation plays a critical role in controlling carrier transport i

60 It is now apparent that p53 plays a critical role in controlling immune recognition

61 This barrier plays a critical role in controlling the acquisition of

62 The marine phosphorus cycle plays a critical role in controlling the extent of globa

63 ranscriptional regulation of gene expression plays a critical role in controlling the inflammatory re

64 The prefrontal cortex (PFC) plays a critical role in curbing impulsive behavior, but

65 Inhibitory neurons, which play a critical role in decision-making models, are ofte

66 oteins made by key brain genes-stoichiometry-plays a critical role in defining the clinical features

67 2A/Bbeta2-mediated dephosphorylation of Drp1 play a critical role in determining the severity of cere

68 Point defects in metal halide perovskites play a critical role in determining their properties and

69 porting the notion that species interactions play a critical role in determining upslope range limits

70 under investigation, these carriers clearly play a critical role in determining what an insect can s

71 The exocyst complex plays a critical role in determining both temporal and s

72 The tumor immune microenvironment plays a critical role in determining response to ICT; th

73 The tumour microenvironment plays a critical role in determining tumour fate.

74 Just as research played a critical role in developing early EHR prototype

75 We suggest that CDNF plays a critical role in development and long-term maint

76 is typically assessed by flow cytometry and plays a critical role in diagnosis, classification, and

77 The size of the cycloalkene rings plays a critical role in dictating the product distribut

78 SARS-CoV-2 asymptomatic infections may play a critical role in disease transmission.

79 , and inflammation within an arthritic joint plays a critical role in disease progression.

80 ssociated with TBI, where acute inflammation plays a critical role in disease progression.

81 e division site and mitotic microtubules and plays a critical role in division plane orientation in p

82 f PrimPol K29-linked ubiquitination by USP36 plays a critical role in DNA replication stress and chem

83 uctural region indicated that these proteins play a critical role in driving in vivo fitness and viru

84 that one or both of the cross-linked regions play a critical role in driving the friction-limited fol

85 s, somatomotor, and posterior insula regions play a critical role in dysconnectivity shared across de

86 Nicotinamide adenine dinucleotide (NAD(+)) plays a critical role in energy metabolism and bioenerge

87 endothelial cell population that ultimately plays a critical role in ensuring appropriate alveolar s

88 strate that RSK2 (p90 ribosomal S6 kinase 2) plays a critical role in ER stress-induced autophagy in

89 dicate that the mIgE B-cell antigen receptor plays a critical role in establishing or maintaining the

90 The orbitofrontal cortex (OFC) plays a critical role in evaluating outcomes in a changi

91 nd CD70 but not CD80/CD86 signaling in cDC1s played a critical role in expansion and antitumor effica

92 The basolateral amygdala (BLA) plays a critical role in fear conditioning and is extrem

93 non-linearity in the acoustic transformation plays a critical role in feature extraction.

94 The National Institutes of Health (NIH) plays a critical role in funding scientific endeavors in

95 Direct Cx43 interaction with ZO-1 plays a critical role in gap junction regulation.

96 Mitochondria play a critical role in generating energy to support the

97 id dendritic cells (pDCs) have been shown to play a critical role in generating viral immunity and pr

98 The kynurenine pathway (KP) plays a critical role in generating cellular energy in t

99 These findings demonstrate that pIC neurons play a critical role in GI malaise perception, and that

100 e., mangroves, salt marshes, and seagrasses) play a critical role in global carbon (C) cycling, stori

101 The deep sea plays a critical role in global climate regulation throu

102 It was found that T cells play a critical role in graft rejection, but can also be

103 The Netrin-1/DCC guidance cue pathway plays a critical role in guiding growing axons toward th

104 Feature screening plays a critical role in handling ultrahigh dimensional

105 GABA interneurons play a critical role in higher brain functions.

106 This eukaryote-specific appended domain also plays a critical role in hLysRS nuclear localization, th

107 . tuberculosis exposure and whether such AwM play a critical role in host defense against M. tubercul

108 Host microbiomes play a critical role in host fitness and health.

109 In contrast, contextual valence plays a critical role in how the PL is recruited in init

110 Our data show that MN1 plays a critical role in human craniofacial and brain de

111 ance imaging and vascular imaging techniques play a critical role in identifying disease mechanisms.

112 s I major histocompatibility complexes (MHC) play a critical role in immune cell recognition and can

113 et, with tumor-associated macrophages (TAMs) playing a critical role in immune suppression.

114 Thus, antibody glycosylation plays a critical role in immune responses to enveloped v

115 (Th) cells are CD4(+) effector T cells that play a critical role in immunity by shaping the inflamma

116 into skin and sites of inflammation, thereby playing a critical role in immunity.

117 n E6 of high-risk human papillomavirus (HPV) plays a critical role in inducing cell immortalization a

118 hat Abeta42/40 ratio, not total Abeta level, plays a critical role in inducing neurofibrillary tangle

119 demonstrated that HIV-induced telomeric DDR plays a critical role in inducing telomere loss, prematu

120 Gut microbiota play a critical role in infant health.

121 Glycosylation within the human host plays a critical role in influenza virus biology.

122 Thus, Chd4 plays a critical role in integrating Fezf2- and Aire-med

123 Necroptosis signaling pathway plays a critical role in intestinal cell injury.

124 d MAPK/ERK-2-mediated phosphorylation of Vpx plays a critical role in its interaction with human Nup1

125 e deacetylases (HDACs), and Tet2 hydroxylase play a critical role in keeping cancer cells in a highly

126 predicts poor diagnosis and outcome but also plays a critical role in leukemia transformation and mai

127 of cytosolic double-stranded RNA (dsRNA) and play a critical role in limiting viral infection.

128 We observe that PD-L1 on DC plays a critical role in limiting T cell responses.

129 Oxidative stress plays a critical role in liver tissue damage and in hepa

130 ed common and rare genetic variants that may play a critical role in lung function among Puerto Rican

131 Immune microenvironment plays a critical role in lung cancer control versus prog

132 th a critical dimension for surface features plays a critical role in maintaining intercellular cohes

133 These results indicate that Tet1 plays a critical role in maintaining the quiescence and

134 Electron-electron interactions play a critical role in many condensed matter phenomena,

135 lters the function of macrophages (M ) which play a critical role in many physiological processes in

136 Microglia play a critical role in many processes fundamental to le

137 mic reticulum (SR) calcium has been shown to play a critical role in mediating mitochondrial dysfunct

138 We show that ORAI2 and ORAI3 channels play a critical role in mediating the regenerative Ca(2+

139 tein, poly(ADP-ribose) polymerase 1 (PARP1), plays a critical role in mediating IAV HA-induced degrad

140 Whether this clustering plays a critical role in membrane fusion is poorly under

141 Thus, hippocampal CIM6P/IGF2R plays a critical role in memory consolidation by control

142 Together, these findings suggest that SETD6 plays a critical role in memory formation and may act as

143 eceptor for advanced glycation end-products) play a critical role in metabolic pathways, which we env

144 Finally, we demonstrate that tamalin plays a critical role in mGluR-mediated internalization

145 ssed homologous proteins in eukaryote cells, playing a critical role in mitochondrial fusion.

146 These results indicate that astrocytic YY1 plays a critical role in Mn-induced neurotoxicity in viv

147 ue to warmer conditions, while precipitation played a critical role in moderating the balance between

148 ations both demonstrated that the surfactant plays a critical role in modifying the surface energy an

149 y indicate that radiation dose fractionation plays a critical role in modulating levels of KLF2, its

150 s to N or P limitation, we suggest S. bescii plays a critical role in modulating stress imposed by li

151 e that genotype at the ABO blood group locus plays a critical role in modulating the platelet HXP phe

152 ve shown that the focal adhesion kinase Pyk2 plays a critical role in monocyte motility.

153 While this strongly argues that the pallidum plays a critical role in motor control, it has been diff

154 ratory activity-which current models suggest plays a critical role in movement initiation-remains unk

155 EF-Tu plays a critical role in mRNA decoding by increasing the

156 NF-kappaB plays a critical role in MS and EAE; however, the effect

157 ile cilia are cellular beating machines that play a critical role in mucociliary clearance, cerebrosp

158 ion (H3K27me3)-mediated epigenetic silencing plays a critical role in multiple biological processes.

159 TEMENT alpha-Synuclein (alpha-syn) pathology plays a critical role in neurodegenerative diseases such

160 ion of tropomyosin receptor kinase B (TrkB), plays a critical role in neuronal proliferation, differe

161 Visceral adipose tissue plays a critical role in numerous diseases.

162 glands (MG) in a process termed meibogenesis-plays a critical role in ocular surface physiology.

163 leted in Colorectal Carcinoma (Dcc) receptor plays a critical role in optic nerve development.

164 f interferon genes (STING) has been shown to play a critical role in orchestrating immune responses t

165 The Hippo pathway, which plays a critical role in organ size control and cancer,

166 Inflammation plays a critical role in osteoarthritis (OA).

167 n using Chlamydia muridarum, IL-1R signaling plays a critical role in oviduct tissue damage.

168 -targeted vaccination, suggesting that cDC1s played a critical role in pDC-mediated cross-priming ind

169 matal conductance (g(s)); therefore, stomata play a critical role in photosynthesis and transpiration

170 ughout life by melanocyte stem cells (MSCs), play a critical role in pigmentation and melanoma.

171 thin layer of soil surrounding plant roots, plays a critical role in plant's adaptation to the envir

172 hat a Rho-guanine nucleotide exchange factor plays a critical role in podocytes.

173 Radiology departments play a critical role in policy and guideline development

174 mprint the host gut mucosal immunity and may play a critical role in precipitating FA.

175 work demonstrates that patrolling monocytes play a critical role in preventing lung tumor metastasis

176 the use of entangled photons in TPA process plays a critical role in probing the detailed electronic

177 transmit signals between synapses and soma, play a critical role in processing functions, such as no

178 Wnt signaling plays a critical role in production and differentiation

179 The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor pr

180 -inducible NAC transcription factor, TaNAC2, plays a critical role in promoting crop growth and nitro

181 The tumor microenvironment plays a critical role in prostate cancer (PC) developmen

182 hat coats all non-keratinized epithelia, and plays a critical role in protecting the human body from

183 proteasome, a complex multisubunit protease, plays a critical role in protein degradation.

184 The periodontal ligament (PDL) plays a critical role in providing immediate response to

185 ules, suggesting that beta-catenin signaling plays a critical role in proximal tubule development.

186 The activation of T helper 17 signaling plays a critical role in psoriasis pathogenesis, and sys

187 signaling mediator in the TLR/IL-1 pathway, plays a critical role in PTB.

188 Twitching motility plays a critical role in redistributing cells on surface

189 r factor erythroid-2-related factor 2 (Nrf2) plays a critical role in reducing oxidative stress by pr

190 specifically Pcdhgc3, Pcdhgc4, and Pcdhgc5, play a critical role in regulating cIN survival during t

191 In this study, we show that alphav integrin plays a critical role in regulating B cell TLR signaling

192 GJ intercellular communication (GJIC) plays a critical role in regulating behaviors of human e

193 dhesion molecule-1 (ICAM-1), a molecule that plays a critical role in regulating blood-to-brain immun

194 DNA methylation plays a critical role in regulating gene expression, gen

195 odeling factor Snf2h (also known as Smarca5) plays a critical role in regulating meiotic cell cycle p

196 Tgf-beta3 plays a critical role in regulating murine palate develo

197 unding a central pair apparatus (CPA), which plays a critical role in regulating proper ciliary funct

198 ivision cycle 23 (Cdc23, also known as APC8) plays a critical role in regulating the oocyte chromosom

199 er, these data indicate that phosphorylation plays a critical role in regulating the structure and fu

200 Nuclear YAP1 plays a critical role in regulation of stem cell prolife

201 Uncertainty plays a critical role in reinforcement learning and deci

202 Because tissue macrophages play a critical role in removing apoptotic/necrotic cell

203 age-gated potassium 11.1 (K(v)11.1) channels play a critical role in repolarization of cardiomyocytes

204 The Hippo (MST1/2) pathway plays a critical role in restricting tissue growth in ad

205 l of Na(+) from the cytosol into the vacuole plays a critical role in salinity tissue tolerance, but

206 overproduction of urates and renal function plays a critical role in serum uric acid levels.

207 e, the relationship between these two spaces plays a critical role in setting range limits.

208 The mammalian male-specific Y chromosome plays a critical role in sex determination and male fert

209 Dendritic cells (DCs) play a critical role in shaping adaptive immunity.

210 ell of origin and the genetic driver lesions play a critical role in shaping the phenotypes of lung t

211 Corneal stiffness plays a critical role in shaping the cornea with respect

212 Overall, hypoxia plays a critical role in shaping the genomic and evoluti

213 ing global phosphorus cycling, and therefore plays a critical role in shaping the global oxygen cycle

214 ivation of NOD2, indicating that MDP sensing plays a critical role in shaping the immune response to

215 channel subfamily V member 3 (TRPV3) channel plays a critical role in skin physiology, and mutations

216 The hippocampus plays a critical role in sleep-related memory processes

217 use effect and energy crisis, and thereby it plays a critical role in solving environmental problems

218 ivating the retrieval (mental frame syncing) plays a critical role in spatial memory recollection.

219 odorants in the environment and consequently play a critical role in species survival.

220 p1) is a neuropeptide and hormone thought to play a critical role in stress response (Stroth et al.,

221 which each nucleus transcribes even-skipped plays a critical role in stripe formation.

222 tor plasticity mediated by the GluA1 subunit plays a critical role in sustaining and amplifying seizu

223 Our results suggest that astrocytes play a critical role in synaptic computation during post

224 EphB2 plays a critical role in synaptic development; its poten

225 e in situ generated oxides/hydroxides, which play a critical role in synergistically reducing energet

226 Here, we report that CD2 costimulation plays a critical role in target cell killing by freshly

227 The results show that S100A4 plays a critical role in tension development in airway S

228 For canid species, scent marking plays a critical role in territoriality, social dynamics

229 cent Tpm molecules define Tpm continuity and play a critical role in the ability of Tpm to cooperativ

230 tic 5-HT(1A) autoreceptor, has been shown to play a critical role in the antidepressant-like actions

231 strated that chromatin modifying enzymes can play a critical role in the conversion to CRPC.

232 nocortinergic circuit that we identified may play a critical role in the counterregulatory response t

233 Adjuvants play a critical role in the design and development of no

234 tivity of nociceptors have been suggested to play a critical role in the development of chronic neuro

235 ary cilia and interstitial inflammation both play a critical role in the disease, the reciprocal inte

236 interactions within the same beta-sheet may play a critical role in the formation of polymorphic fib

237 xal 5'-phosphate (PLP)-binding proteins that play a critical role in the homeostasis of vitamin B(6)

238 Polymorphonuclear neutrophils (PMNs) play a critical role in the innate immune response to in

239 neurons located in the lateral hypothalamus play a critical role in the maintenance of arousal and c

240 ata and explain how periodic microstructures play a critical role in the midinfrared.

241 mu-Opioid receptors (mu-ORs) play a critical role in the modulation of pain and media

242 Fibroblast-like synoviocytes (FLS) play a critical role in the pathogenesis of rheumatoid a

243 impaired KIF21B autoregulation and function play a critical role in the pathogenicity of human neuro

244 gests that bone marrow-derived myeloid cells play a critical role in the pathophysiology of pulmonary

245 al peptide-expressing (VIP) interneurons may play a critical role in the proper development and funct

246 Consequently, RNA-binding proteins play a critical role in the regulation of mRNA and prote

247 piRNAs play a critical role in the regulation of transposons an

248 s have been linked to flash droughts and can play a critical role in the spread of human ignited wild

249 The Akt/mTOR pathway played a critical role in the AML-EV-induced phenotypica

250 iously associated with monogenic disease and plays a critical role in the activation and function of

251 These AAA unfoldases include spastin, which plays a critical role in the architecture of eukaryotic

252 plaque, and the formation of F-actin patches plays a critical role in the assembly of gap junction ch

253 evidence that BZR1-dependent ROS production plays a critical role in the BR-mediated regulation of t

254 Dopamine (DA) plays a critical role in the brain, and the ability to d

255 Importantly, the TP53-stabilizing DINO plays a critical role in the cell death response of HPV1

256 d breaks, MAD2L2-containing shieldin complex plays a critical role in the choice between homologous r

257 1)/eyes absent (EYA) transcriptional complex plays a critical role in the development of multiple org

258 MOF-mediated acetylation plays a critical role in the DNA damage response (DDR) a

259 TREM-1 plays a critical role in the eCIRP-mediated increase of

260 stin et al., we suggest that spatial context plays a critical role in the encoding and retrieval of e

261 Excessive serotonin (5-HT) signaling plays a critical role in the etiology of alcohol use dis

262 Hepatic LDLr plays a critical role in the flow of macrophage-derived

263 lpha (ERalpha), but not ERbeta, in the liver plays a critical role in the formation of estrogen-induc

264 For example, iron plays a critical role in the generation of reactive oxyg

265 ozone-depleting agent, nitrous oxide (N(2)O) plays a critical role in the global climate.

266 pped DNA intermediate, and the ligation step plays a critical role in the joining of noncomplementary

267 ppocampal neurons, we show here that tamalin plays a critical role in the ligand-dependent internaliz

268 Intracranial pressure monitoring plays a critical role in the management of severe trauma

269 ew is incorrect, and that solvation dynamics plays a critical role in the mechanism.

270 DNA-dependent protein kinase (DNA-PK) plays a critical role in the non-homologous end joining

271 microglia/macrophages at the site of injury plays a critical role in the onset of many pathological

272 ptibility and reinforces the concept that RA plays a critical role in the pathophysiology of arrhythm

273 d metabolite, sphingosine 1-phosphate (S1P), plays a critical role in the pDC functions and interfero

274 Endoscopy plays a critical role in the posttransplant management o

275 , a pyridoxal 5'-phosphate-dependent enzyme, plays a critical role in the progression of hepatocellul

276 Interferon (IFN) type I plays a critical role in the protection of mice from let

277 The protein kinase PfCLK3 plays a critical role in the regulation of malarial para

278 the needs of regulatory agencies, where AUC plays a critical role in the solution-based characteriza

279 ibitory synaptic transmission within the NAc plays a critical role in the stress response.

280 Hence, Dot1l plays a critical role in the thermogenic program and may

281 The higher-order structure (HOS) of proteins plays a critical role in their function; therefore, it i

282 n antigens and thus, their genetic diversity plays a critical role in their functions.

283 tial gene in E. coli and S. typhimurium that plays a critical role in their virulence by changing the

284 , we show that histone acetyltransferase MOF plays a critical role in this process through directly a

285 Xase complex by showing that exosite binding plays a critical role in this process, which they descri

286 The human leukocyte antigen (HLA) locus plays a critical role in tissue compatibility and regula

287 In plants and mammals, DNA methylation plays a critical role in transcriptional silencing by de

288 ns.SIGNIFICANCE STATEMENT The olfactory bulb plays a critical role in transforming broad sensory inpu

289 region but also in codingregion of transgene plays a critical role in transgene expression regulation

290 Hospital systems play a critical role in treating injuries during disaste

291 (CAFs) and extracellular matrix (ECM), which plays a critical role in tumor initiation, progression,

292 oteins are frequently hijacked in cancer and play a critical role in tumorigenesis.

293 hat l-methionine (l-Met) and its metabolites play a critical role in tumorigenesis.

294 Particle phase state plays a critical role in understanding and predicting ae

295 Multiple-choice examinations play a critical role in university admissions across the

296 internal RNA modification of mammalian mRNA, plays a critical role in various developmental processes

297 aptor STING (stimulator of interferon genes) play a critical role in vascular inflammation and destru

298 des in the Golgi apparatus and is thought to play a critical role in vesicular trafficking.

299 astic reduction of lipid droplets (LDs) that play a critical role in virus assembly.

300 by transforming growth factor-beta (TGFbeta) play a critical role in wound healing.