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1 At 14 weeks, patients in the combined trials had a mean change from baseline in LDL cholesterol lev
4 Grave faults in design and conduct of clinical trials have also substantially contributed to the failure of
9 ive in specific Ph-like ALL subsets, and precision medicine trials have been initiated for this high-risk ALL subset.
11 yet been conclusively determined as no randomized clinical trials have been published on this issue, and their effective
16 Recent exploratory subgroup analyses of the large phase 3 trials have demonstrated that patients with chronic hepatitis
20 first- and second-generation EGFR TKI, and recent clinical trials have documented their efficacy in patients with EGFR-m
21 es in cardiovascular medicine fueled by innovative clinical trials have dramatically improved the lives of patients world
24 The successes and failures of biologics in clinical trials have facilitated our ability to better understand whic
25 However, meta-analyses of vitamin D supplementation trials have failed to show clear improvements in blood pressu
26 Although case series and controlled prospective trials have found the procedure to be safe, it is unclear whe
29 blood cells can be stored for up to 6 weeks, but randomized trials have not assessed the effects of this final week of st
30 relatively rare disorder, and as such, large-scale clinical trials have not been completed, rendering management decision
34 Successes achieved in both animal models and human clinical trials have proven ASOs both safe and effective.
35 esults from large cohort studies and randomized, controlled trials have provided conflicting messages about the benefits
39 al infarction (STEMI) has been widely used; however, recent trials have questioned its value and safety.
40 mprove outcomes for patients with hepatorenal syndrome, but trials have reported variable efficacy.
48 ds to oligodendrocyte death and demyelination, and clinical trials have tested glial transplants to promote myelin repair
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