1                                                Measurements were compared between groups with a Mann-Whitney test, and me

2 ined as the proportion of patients with at least 1 adenoma) were compared between groups, with a noninferiority margin (r

3                                             Various factors were compared between groups with and without anxiety and dep

4                  Demographic and phenotypic characteristics were compared between groups with and without molecular diagn

5    Changes in BMD were adjusted for confounding factors and were compared between groups with either low (< or =300 mg/d)

6  difficulty of repair, PGY-level, and patient comorbidities were compared between groups with mixed effects-ANOVA and gen

7 -wise free water and fractional anisotropy of tissue (FA-t) were compared between groups with Randomise running in FSL.

8 tment outcomes (cure, failure, death, or loss to follow-up) were compared between groups with respect to glycemic status

9                                               Outcome rates were compared between groups with the Cochran-Mantel-Haenszel

10 c wall redundancy and prevalence of specific gene mutations were compared between groups with the Fisher exact test.

11                                Week 12 TFV-DP distributions were compared between groups with the Wilcoxon test.

12                                Week 12 TFV-DP distributions were compared between groups with Wilcoxon test.