ライフサイエンスコーパス: , designated

1 Both F(ab)s, designated 1D10 and 2G10, were bound specifically and

2 Here, we constructed five vaccine candidates, designated 2012-RBD, 2013-RBD, 2014-RBD, 2015-RBD, and

3 pression of a TDP-43 CTF (amino acids 208-414, designated 208 TDP-43 CTF), previously identified in F

4 broadly reactive monoclonal antibodies (mAbs), designated 3/11 and AP33, recognizing a distinct, but

5 ations in chromosomal genes tc0237 and tc0668 (designated a chromosomal mutant) or deficient in plasm

6 mutant) or deficient in plasmid-encoded pGP3 (designated a plasmid mutant) is unable to do so.

7 Five clusters (designated A through E) were distinguished by indicato

8 sus clones of L10 (designated SFV6) and A7(74) (designated A774wt) were used to construct a panel of

9 dicated that the protein encoded by this gene, designated AAEL001915, belongs to a clade of RTKs rela

10 H) binding domains against both TcdA and TcdB (designated "ABA") that reverses fulminant CDI in mice

11 with equal numbers of a prototype ABSA strain, designated ABSA 1014, and any one of several UPSA stra

12 ncoding a 30-kDa Ae. aegypti salivary protein, designated Aed a 3, was isolated from an expression li

13 dividual ALV subgroup E (ALV-E) field strains, designated AF227 and AF229, were isolated from two dif

14 m the RubyACR from Aurantiochytrium limacinum (designated AlACR1) under single-turnover excitation ex

15 subunit of a respiratory antimonate reductase, designated anrA.

16 SP, preparative separation into two fractions, designated anthocyanins (AF) and copigments (CF), was

17 We demonstrate in this article that this CAR, designated anti-PSCA-DAP12, consisting of DAP12 fused

18 calcium-dependent membrane-targeting protein (designated Arabidopsis [Arabidopsis thaliana] Soybean

19 oteins, two peptides with an unknown function (designated ARACIN1 and ARACIN2) have been identified.

20 redicted LacI-type transcription factors (TFs), designated AraQ and MalR1, are involved in regulating

21 Fields with different levels of productivity (designated as "most" and "least" productive fields) we

22 spartic acid (designated as D-Tg) or alanines (designated as A-Tg).

23 activator that binds to a conserved sequence (designated as AW box) boxes in the promoters of many g

24 to alanine, C54A,C61A,C65A, C187A,C192A,C198A (designated as C6A); N55I; and Q58L).

25 , and Ser(227) were replaced by aspartic acid (designated as D-Tg) or alanines (designated as A-Tg).

26 creatic resection databases of 3 institutions (designated as institutions A, B, or C) were queried on

27 The ectopic expression of rice DGAT1 (designated as OsDGAT1-1 and OsDGAT1-2) genes restored

28 e generated an RRV-TUCH rotavirus reassortant (designated as T(R(VP2,VP4)) ) that when injected into

29 1 located on homoeologous group 3 chromosomes (designated as TaG3NPR1) and three on homoeologous grou

30 and three on homoeologous group 7 chromosomes (designated as TaG7NPR1).

31 we derived PSCs from mice, horses, and humans (designated as XPSCs) that are permissive for direct PG

32 It appears that the two NEIL3 Zf-GRF motifs (designated as Zf-GRF repeat) are dispensable for its D

33 d zinc finger motifs containing GRXF residues (designated as Zf-GRF).

34 were previously Sanger sequenced, with 55 (61%) designated as carrying the wild-type pncA gene and 33

35 atomic isotopes ((12)C 98.89% or (1)H 99.9844%, designated as (12)C or (1)H, respectively).

36 eletion in the third intracellular loop (ICL3) (designated as GPRC6A(ICL3_KGKY)) that replaces the an

37 antly impaired in Rag1(-/-)Rag2(-/-)Il2rg(-/Y) (designated as SD-RG) rats.

38 x 5 regimen, reaching a plateau at 60 mg/m(2) (designated as the biologically effective dose).

39 0% of frontotemporal lobar degeneration (FTLD), designated as FTLD-TDP.

40 But notice, designated as a fundamental privacy principle in a dif

41 a and proinsulin 2 (PI2)-deficient background, designated as A22Calpha(-/-)PI2(-/-) NOD mice.

42 cterize another such factor encoded by PD0956, designated as an antivirulence secreted protease "PrtA

43 phylogenetically divided into eight clusters, designated as APN1-8.

44 o auxiliary iron-sulfur cluster binding sites, designated as AuxI and AuxII, use distinctive ligands

45 -engineered the extracellular regions of beta, designated as beta-c1, for prokaryotic production to b

46 uce BoNT serotype B (BoNT/B) and a novel BoNT, designated as BoNT/H.

47 a monophyletic clade of nine fungal TPS genes, designated as BTPSL for bacterial TPS-like genes, from

48 pation of a distantly related partner protein, designated as CPT-binding protein (SlCPTBP), which is

49 Our methodology, designated as CRISPR RNP Electroporation of Zygotes (C

50 The novel endonuclease, designated as Endonulcease Q (EndoQ), recognizes uraci

51 l and molecular features from mice and humans, designated as extended pluripotent stem (EPS) cells, w

52 vel subtype of familial partial lipodystrophy, designated as FPLD4.

53 These patients, designated as having proportionate MR, respond favorab

54 These patients, designated as having severe but disproportionate MR, r

55 pecifically controlling awn development on LR, designated as Lsa1 for lateral spikelet awnless 1.

56 a P3-inducible U-box type E3 ubiquitin ligase, designated as P3-inducible protein 1 (P3IP1), which in

57 The dissociation constant of the best aptamer, designated as P4G13, was estimated to be 17 nM by elec

58 identified a secreted glycoprotein of 15 kDa, designated as Ppal15kDa, using liquid chromatography t

59 there are two D14 homologs in P. trichocarpa, designated as PtD14a and PtD14b that are over 95% simi

60 nd distinct molecular and functional features, designated as region-selective pluripotent stem cells

61 air that resembles and is linked to RRS1/RPS4, designated as RRS1B/RPS4B, which confers recognition o

62 at directly or indirectly associate with SR45, designated as SR45-associated RNAs (SARs).

63 ural antisense transcript at the MALAT1 locus, designated as TALAM1, that positively regulates MALAT1

64 This clinical entity, designated as the 'cannabis-fruit/vegetable syndrome',

65 This complex, designated as the 'florigen activation complex' (FAC),

66 zing the protein import apparatus of plastids, designated as the translocon at the outer and inner en

67 Deletion of seven genes within G-LSR2, designated as VdDf genes, produced the nondefoliation

68 This gene, designated as WHEAT TANDEM KINASE 2 (WTK2), confers in

69 Three antigenic sites, designated AS108, AS112 (an N-terminal E1 site), and A

70 The complex contains eight subunits (designated AUG) including AUG8, which is an MT-associa

71 We show that, for the first of these mutants, designated awake1, the maternal allele is required for

72 Characterization of the stalled complexes (designated B(028)) revealed that U4/U6 snRNP proteins

73 e but rather a beta-1,4-glucuronyltransferase, designated B4GAT1, towards both alpha- and beta-anomer

74 f bezafibrate and medroxyprogesterone acetate (designated BaP) has potent in vivo anticancer activity

75 An algorithm, designated "BBB Score", composed of stepwise and polyn

76 The prototypic design, designated BG505 SOSIP.664, incorporates an intersubun

77 The recombinant proteins, designated BiFae1A and BiFae1B, were functionally assi

78 BaMn3Ti4O14.25, designated BMT-134, possesses the signature channel-li

79 ralizing diverse HIV-1 primary virus isolates (designated broadly neutralizing antibodies [bNAbs]) re

80 f this network derives from graded expression, designated by antigen receptor signal strength, of a p

81 entified a novel cellulose synthase inhibitor, designated C17.

82 primary C3 activation fragment-derived ligand, designated C3d, it coassociates with CD19 on B cells t

83 These cells (designated CAF-MSCs) enhanced in vitro neuroblastoma c

84 study, an R2R3-MYB transcription factor gene, designated CaMYB31, was isolated and characterized in

85 hospitals and National Cancer Institute (NCI) -designated cancer centers within federal exchange net

86 ived care at a National Cancer Institute (NCI)-designated cancer center (8.6% [95% CI, 8.1%-9.2%] amo

87 tain one of 69 National Cancer Institute (NCI)-Designated Cancer Centers.

88 platform for the detection of small molecules, designated CaT-SMelor (CRISPR-Cas12a- and aTF-mediated

89 caused by expansion of specific sub-lineages, designated CC17-A1, CC17-A2 and CC23-A1.

90 he proportion of infiltrating CD20(+) B cells (designated CD20Hi and CD20Lo, respectively).

91 ver CD34+ cells were comprised of two subsets, designated CD34+CD146+ and CD34+CD146-, and hematopoie

92 We have developed a DSB repair assay system, designated CDDR (CRISPR-Cas9-based Dual-fluorescent DS

93 and care at a National Cancer Institute (NCI)-designated center (OR 1.70, CI 1.58-1.82).

94 nclude with the identification of compound 48 (designated CFI-400945) as a novel clinical candidate f

95 K223 include a predicted alpha-helical region (designated CH) immediately preceding the conserved C-t

96 generate chemically switchable split nanobody (designated Chessbody) for ligand-gated antigen recogni

97 a (CIN) grades 2-3 and adenocarcinoma in situ (designated CIN2+) from the HPV Vaccine Impact Monitori

98 describe here a human antibody clonal lineage, designated CL6649, members of which bind a third conse

99 The genomic sequence of the resistant virus, designated clone 7, contained mutations in 16 open rea

100 nase in Magnaporthe oryzae, and urate oxidase (designated ClUrase) were functionally characterized.

101 two separable regions of the C-terminal tail, designated cluster 1 (Thr(347), Thr(349), and Ser(350)

102 The resultant population, designated CMG28, displays markedly reduced in vitro d

103 These new molecular entities, designated "CNS neuroblastoma with FOXR2 activation (C

104 The triple helix, designated Col108, is expressed in Escherichia coli us

105 atment alone or in combination with anti-CD20 (designated combo therapy) inhibited T1D development.

106 and AKU mice novel microanatomical structures, designated concentric lamellae, were identified surrou

107 The demethylation of a specific CpG site (designated CpG 2), which is juxtaposed to a key cAMP-r

108 ntification of a cDNA for a DGAT1-type enzyme, designated CpuDGAT1, from the transcriptome of C. avig

109 as9 and a modified guide RNA scaffold gRNA2.0 (designated CRISPR-Act2.0) yielded stronger transcripti

110 However, the second enzyme (designated CsGA1ox/ds) performed multiple reactions, i

111 The antibody, designated CT149, was isolated from convalescent patie

112 A newly identified hantavirus, designated Dakrong virus (DKGV), was detected in one o

113 The mutation, designated dek38-Dsg, is embryonic lethal, has a defec

114 inant GPCMV with a targeted deletion of gp145 (designated Delta145), a viral protein kinase R (PKR) i

115 oxed Irf8 and Spi1 (encoding PU.1) by Mb1-Cre (designated DKO mice) in the B cell lineage resulted in

116 of T-cell acute lymphoblastic leukemia (T-ALL), designated early T-cell precursor ALL, which is chara

117 singly, the EDM of TTF-1(+) lung cancer cells (designated EDM-TTF-1(+)) displayed an anti-angiogenic

118 ization of the E. festucae antifungal protein, designated Efe-AfpA.

119 We identified 2 zebrafish elavl1 genes, designated elavl1a (the predominant isoform during emb

120 fy an Arabidopsis thaliana long-noncoding RNA, designated ELF18-INDUCED LONG-NONCODING RNA1 (ELENA1),

121 A new catalytically active zeolite, designated EMM-17 (ExxonMobil Material-17), with a thr

122 of a synthetic model complex ([Fe6S9(SEt)2](4-); designated Fe6(RHH)) into the catalytic component of

123 Two new methods, designated filter-capture DNA isolation (FCDI) and fil

124 ry and characterization of a second polymorph, designated Form II, which can be isolated as single cr

125 asurements estimated by 2 mathematical models (designated Formula 1 and Formula 2) were compared to t

126 (Foxj1 and Scgb1a1) for a floxed-Stat1 allele (designated Foxj1-Scgb1a1-Cre-Stat1(f/f) mice) to targe

127 The wheat homologue of FT, designated FT1 (= VRN3), activates expression of VRN1

128 rotein was identified as myosin light chain 1, designated Gallus domesticus 7 (Gal d 7).

129 mon features including a structural signature, designated "gamma-core motif".

130 Null mutants for GCS (designated 'gcs-1') were viable as seedlings, albeit s

131 propose the establishment of a new GH family, designated GH161.

132 In this study, we report a GI (designated GIVchS12) from a non-O1/O139 strain of V. c

133 at the F. fujikuroi polyketide synthase PKS13, designated Gpy1, is responsible for gibepyrone A biosy

134 These mAbs, designated group A, display high binding affinities fo

135 Another mAb, designated group B, inhibits fVIII procoagulant activi

136 icomponent RNA virus isolated from mosquitoes, designated Guaico Culex virus (GCXV).

137 by the orthologous human ICR (hIC1) sequence, designated H19(hIC1) We show that hIC1 can functionall

138 oultry markets detected three A(H5) genotypes, designated H5N1-R1, H5N1-R2, and H5N2-R3, that arose f

139 as the cause of severe respiratory infections, designated hantavirus pulmonary syndrome, with case fa

140 titis B virus core protein (HBc) as a carrier, designated HBc-E1/2.

141 compassing aa 412 to 423 revealed two subsets, designated HC33 HMAbs.

142 broadly neutralizing combinations of two NAbs, designated HEPC74/HEPC98, also displayed enhanced pote

143 We found that one enzyme (designated here CsGA3ox5) has GA 3-oxidation activity.

144 tigenic site on the globular head domain of F, designated here antigenic site VIII, which occupies an

145 NCgl2764/Rv0224c encodes a methyltransferase, designated here as MtrP.

146 Using transposon mutagenesis, a gene, designated hmpF, was identified as involved in motilit

147 biopsy specimen-derived EBV (NPC-EBV) genomes, designated HN1 to HN18.

148 One AS, designated Homo sapiens keratin 7 (KRT7-AS), was selec

149 With appropriate precautions and resources, designated hospitals in the United States can safely p

150 ying the pathobiology of HPV-associated OPSCC (designated HPV(+) OPSCC) remain unclear.

151 optimized expectation-maximization algorithm, designated HPV-EM, to address the ambiguities caused b

152 into a highly specific aggregation inhibitor (designated HTB1M) of two familial amyotrophic lateral

153 Here we show that the HU-308 enantiomer, designated HU-433, is 3-4 orders of magnitude more pot

154 um smegmatis has two such [NiFe] hydrogenases, designated Huc and Hhy, that belong to different phylo

155 de units on both sides of the porphyrin plane (designated "HuPhyrin") have been effectively construct

156 rections by strand-displacement amplification, designated hybridization cascade plus strand-displacem

157 activity of at least six maturation proteins, designated HypA-F.

158 This enzyme, designated IgdE forimmunoglobulinG-degradingenzyme ofS

159 essor of a placental-specific Igf2 transcript (designated Igf2-P0) in mice.

160 that protects neurons and limits inflammation, designated "immune privilege." However, there is not a

161 e expressing the Notch-4 intracellular domain (designated Int3) in the mammary gland have two phenoty

162 Here we describe an insecticidal protein, designated IPD072Aa, that is isolated from Pseudomonas

163 T3 substrate and identified JAK3 inhibitor VI (designated JI6 hereafter) as a novel FLT3 inhibitor, w

164 ed in coupling a pair of [Fe(4)S(4)] clusters (designated K1 and K2) concomitant with carbide inserti

165 olation, and two virus isolates were obtained, designated Karyana virus (KARYV) and Kundal virus (KUN

166 we report a novel C-terminal Hsp90 inhibitor, designated KU675, that exhibits potent antiproliferati

167 insertion into an [Fe(8)S(9)C] cofactor core (designated L) on NifB.

168 ibe a mutant murine methionyl-tRNA synthetase (designated L274GMmMetRS) that charges the noncanonical

169 ce, almost entirely due to a single phylotype, designated Lactobacillus 4228.

170 e near-complete cranium of a large individual, designated LES1, with an endocranial volume of approxi

171 Remarkably, one copy, designated LeuRS-I, had key amino acid substitutions w

172 A monoclonal antibody, designated LM26, binds to the cell wall of phloem siev

173 smembrane helices and two large luminal loops, designated Loop1 and Loop7.

174 lethanolamine (LPE) with acyl-coenzyme A (CoA), designated LYSOPHOSPHATIDYLETHANOLAMINE ACYLTRANSFERA

175 We studied the expression of the gene, designated M truncatula Cystathionine-beta-Synthase-li

176 9-1370 fusion N (6)-adenine methyltransferase, designated M.HpyAXVII.

177 ion at its cofactor center ([(Cit)MoFe7S9C](n-); designated M-cluster).

178 009-16 showed emergence of a new emm1 lineage (designated M1(UK))-with overlap of pharyngitis, scarle

179 parental m1 VacA protein, a chimeric protein (designated m2/m1) containing m2 sequences in the N-ter

180 This neutralizing MAb, designated MAb EBOV237, recognizes an epitope in the g

181 alis secretes nanosized exosome-like vesicles, designated MalaEx, that carry allergens and can induce

182 Four molecular endotypes for sepsis, designated Mars1-4, were identified in the discovery c

183 n was distributed into 8 distinct MC profiles, designated MC-1 to MC-8.

184 s in DNA methylation and expression of Isyna1 (designated mIno1), which encodes the rate-limiting enz

185 rial haplotypes from different mouse strain(s)-designated Mitochondrial Nuclear Exchange (MNX)-we sho

186 Here, we show that a dominant mutation (designated mlaA*, maintenance of lipid asymmetry) that

187 of mutagenized seeds identified a mutant line, designated MO12, which produced brown seeds as opposed

188 One transgenic event, designated MON88702, has been selected for further dev

189 ydrophobic base of the capsid (core) proteins, designated motifs I, II, and III, are highly conserved

190 Here we report a novel bioluminescence assay, designated MPO activity on a polymer surface (MAPS), f

191 encodes 11 homologues of plant PR-1 proteins, designated MpPR-1 proteins, but their precise mode of

192 sive disease caused by drug-resistant strains, designated MRSA (methicillin-resistant S. aureus), is

193 independent nsp15 mutant mouse coronaviruses, designated N15m1 and N15m3, and found that these virus

194 overy of a diversified family of fish viruses, designated nackednaviruses, which lack the envelope pr

195 ns belong to a previously undescribed variant, designated NAPCR1.

196 n-collagenous (NC) 1 domain, a 28-kDa peptide, designated NC1-peptide, from the C-terminal region, vi

197 ) into the catalytic component of nitrogenase (designated NifDK(apo)).

198 ing the conformation of the resultant protein (designated NifDK(Fe)) similar to the one upon insertio

199 firmly establishing the M-cluster-bound NifEN (designated NifEN(M)) as the only protein other than Ni

200 20 encodes two putative nickel import systems, designated Nik and Ynt.

201 This GECI, designated NIR-GECO1, enables imaging of Ca(2+) transi

202 Here, we report 2 improved NIR GECI variants, designated NIR-GECO2 and NIR-GECO2G, derived from NIR-

203 Five homologous genes, designated NnOMT1-5 and encoding polypeptides sharing

204 37L) in NOD mice using the CRISPR/Cas9 system (designated NOD.Tnfsf9 (-/-)).

205 ngrafted with human tissues 1 day after birth (designated NSG-1d mice) were highly susceptible to inf

206 We isolated a 1000th generation descendant, designated NT that exhibited increased biofilm and agg

207 Whole-genome sequences of the isolate, designated NVAV strain Te34, were identical to that am

208 o recombinant hypoallergenic mosaic molecules, designated P and Q, which were constructed out of elem

209 compounds with isomeric 15-carbon acyl lipids, designated P-A1 (linear lipid), P-A2 (anteiso lipid),

210 1) and N-terminally truncated P proteins (tPs), designated P2, P3, P4, and P5.

211 ergo limited proteolysis to yield two domains, designated p33 and p55.

212 e also noted that Lp01 lacks a mobile element, designated p45, whose presence correlates with virulen

213 , we evaluated synthetic, poly-basic peptides, designated p5 and p5+14, as alternative radiotracers f

214 ide libraries, we identified a tetramer (FSSE, designated P5779) as a specific MD-2 antagonist preven

215 study characterized an E. coli O157:H7 strain, designated PA2, that belongs to the hypervirulent clad

216 The PD-L1-overexpressing platelets (designated PD-L1 platelets) accumulate in the inflamed

217 e, we describe the isolation of a pen3 allele, designated pen3-5, that encodes a dysfunctional protei

218 d cloned from Vietnamese P. monodon specimens, designated Penaeus monodon metallodensovirus (PmMDV).

219 One variant, designated PG9_N100(F)Y, possessed increased potency a

220 identify a family of nuclear protein kinases, designated Photoregulatory Protein Kinases (PPK1-4; fo

221 uct genomes of two genotypes of a novel virus, designated PhV1 type A and PhV1 type B.

222 d a unique mouse Pneumocystis surface protein, designated Pneumocystis cross-reactive antigen 1 (Pca1

223 bonucleotides to the 3' termini of these RNAs (designated poly(UG) or pUG tails)(5).

224 ylated into various lipid signaling molecules, designated polyphosphoinositides (PPIs).

225 have been identified in Arabidopsis thaliana--designated PORA, PORB, and PORC--that are differential

226 Here, a novel circovirus, designated porcine circovirus 3 (PCV3), was identified

227 )/Osx-Cre(+/-) genotypic male and female mice (designated postnatal-OIRKO).

228 This putative photoperiod insensitive allele (designated Ppd-A1a.4) includes a 684 bp deletion which

229 ugh the use of an alternate upstream promoter, designated Pro1, that is active only in immature NK ce

230 ets by extending long cytoplasmic protrusions, designated proplatelets, into sinusoidal blood vessels

231 equences of type 2 PRRSVs, a consensus genome (designated PRRSV-CON) was generated by aligning these

232 dihydroxyphenyl)sulfonyl]isoindoline-4,6-diol, designated PS10, inhibits all four PDK isoforms with I

233 folium cytochrome P450 family member, CYP82Q3 (designated Pyrethrolone Synthase; TcPYS), appeared to

234 lidated data set, we trained a neural network, designated Q1VarPred, specifically for predicting the

235 (p.Arg167Glu) or c.518_519GC>AG (p.Arg173Glu), designated R167Q or R173Q mice, respectively, were ge

236 don tetranucleotide manner when overexpressed, designated readthrough-inducing tRNAs (rti-tRNAs).

237 that has been optimized for clinical samples, designated REFtb, along with a more specific fluorogen

238 ynthetic bacterium Rhodopseudomonas palustris, designated regulatory proteins RpBphP2 and RpBphP3, ar

239 The new 143.9-Mb reference sequence, designated Release 6, effectively exhausts clone-based

240 mutations yielding constitutive Rgg2 activity, designated Rgg2Sp*, were identified, and five of them

241 e three right open reading frame kinase genes (designated riok-1, riok-2 and riok-3).

242 der region of the mRNA specifying the protein, designated Roc for regulator of colonization.

243 pose that these previously unidentified cells, designated "rogue GC B cells," are a major driver of a

244 >95%) short-chain galactooligosaccharide (GOS), designated "RP-G28," significantly improved clinical

245 An infectious clone of one such mutant virus, designated rP11, appeared to be genetically stable in

246 domas secreting mAbs with anti-LukAB activity (designated SA-13, -15, and -17) were generated from B

247 The samples, designated SAM2X5-600 and SAM2X5-630, are X-ray amorph

248 Here we report a new microporous MOF (designated SBMOF-2) that is selective toward Xe over K

249 ogenetically distinct clades of S Senftenberg, designated SC1 and SC2, harboring variations in Salmon

250 The vibriophage, designated Seahorse, was classified in the family Siph

251 here the discovery of two novel DNA sequences, designated SEGS-1 and SEGS-2 (forsequencesenhancinggem

252 three SEIPIN homologs in Arabidopsis thaliana, designated SEIPIN1, SEIPIN2, and SEIPIN3.

253 This classifier, designated SeptiCyte Lab, was validated using reverse

254 Consensus clones of L10 (designated SFV6) and A7(74) (designated A774wt) were u

255 Integrity of this CRE, designated SL9266 (alternatively 5BSL3.2), is critical

256 9266 forms the core of an extended pseudoknot, designated SL9266/PK, involving long distance RNA-RNA

257 The first 100 amino acids of SM (designated SM N100) are necessary for this degradative

258 We investigated the function of the protein, designated Spc (short pilin chaperone), encoded by the

259 /XDR isolates belonged to a subclade of ST298 (designated ST298*) of which 100% (21/21) were MDR and

260 culine poppy mutants revealed a genetic locus, designated STORR [(S)- to (R)-reticuline] that encodes

261 The bacterium, designated strain MLFW-2, is a sporulating member of a

262 chemoautotrophic As(III)-oxidizing bacterium, designated strain SY, was isolated from an As-contamin

263 Six subclades (designated subclades A-F) were identified within clade

264 We identified a Samd4 missense mutation, designated supermodel, that caused leanness and kyphos

265 Eight disparate tissue T cell subtypes (designated T1-T8) were identified, with T7 and T8 enri

266 The TAM also consists of an OMP, designated TamA, and a single inner membrane (IM) prot

267 esized a novel class of glucoside amphiphiles, designated tandem malonate-based glucosides (TMGs).

268 the set of messenger RNAs targeted by miR-218, designated TARGET(218), defines a neuronal gene networ

269 cloned and characterized from T. cinnabarinus (designated TcCPR).

270 y a short element upstream of the restart AUG, designated "termination upstream ribosomal binding sit

271 Atg13, and mutation of these residues to AAAA (designated the FIP200-4A mutant) abolished its canonic

272 SAM cluster) and a [Fe4S4]-like cluster pair (designated the K cluster) that can be processed into a

273 ed into an [Fe8S9] precursor to the M cluster (designated the L cluster).

274 erization of an eight-iron cofactor precursor (designated the L*-cluster), which is proposed to have

275 that, upon maturation of a cofactor precursor (designated the L-cluster) on NifEN, the cluster specie

276 cluster pair into an [Fe(8) S(9) C] precursor (designated the L-cluster) prior to insertion of Mo and

277 c scaffold for the cofactor of Mo-nitrogenase (designated the M-cluster).

278 eins containing a SAM-binding [Fe4S4] cluster (designated the SAM cluster) and a [Fe4S4]-like cluster

279 we report on transcellular transport of a CPP, designated the CL peptide, that increases the delivery

280 n FH and a group of closely related molecules, designated the FH-related (FHR) proteins, are currentl

281 (FEN1) plus hairpin DNA probe (hpDNA) system, designated the HpSGN system, for both DNA and RNA edit

282 This motif, designated the hypoxia-responsive promoter element, is

283 amylin, a non-amyloidogenic variant of amylin, designated the Line 44 model.

284 In humans, there are only two TPST isoforms, designated TPST1 and TPST2.

285 The concept, designated Traceback, was prompted by the recognition

286 This process, designated 'trained immunity', is initiated by modulat

287 cifically with a C-terminal domain of Treslin (designated TRCT).

288 composed of a number of distinct phylogroups, designated types IA1, IA2, IB, IC, II, and III, which

289 e derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four

290 t A2AR gene produces a 134-amino acid protein (designated uORF5).

291 expressing one of the 12 modified HA antigens (designated V1 to V12), COBRA HA antigens, or wild-type

292 s generate distinct organelle-like structures, designated viral replication factories.

293 The RdRp, designated VP1, is active inside the DLP; each VP1 ach

294 vel wer mutant from a genetic enhancer screen, designated wer-4, that exhibits an abnormal pattern of

295 KP) with putative kinase-pseudokinase domains, designated WHEAT TANDEM KINASE 3 (WTK3).

296 tance is conferred by a single dominant locus, designated Xo1, that maps to a 1.09 Mbp fragment on ch

297 undancy, CD103(-/-) mice were crossed to mice (designated Y3) whose T cells expressed a mutant IL-2Rb

298 from the stem region of ZIKV envelope protein, designated Z2, potently inhibits infection of ZIKV and

299 glycyl-glycyl-cysteine peptide-based chelator (designated ZHER2:V2) has the best biodistribution prof

300 A notable variant, designated "ZipACR", is particularly promising for inh