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1 ted a mean vertebrate decline of more than 50% since 1970 (Living Planet Index(2)).

2 used by the Danish Breast Cancer Group (DBCG) since 1982.

3 red in francophone Africa, a decrease of 45.3% since 1990.

4 irst cART in the Swiss HIV Cohort Study (SHCS) since 1996.

5 Despite this, since 1997, dollars invested in PDAC research produced

6 tewide species richness has increased by ~ 10% since 2001.

7 ting in cumulative catch losses ranging 76-91% since 2003.

8 ifrons stable and O. taurus increasing by 800% since 2003.

9 th white race), and more recent entry to care (since 2005 compared with 1994-2004).

10 s early diagnosis of PDAC has decreased by 19% since 2007.

11 e of atmospheric methane concentration (XCH(4)) since 2007, but remains debated.

12 overage in the city of Rio de Janeiro, Brazil, since 2008.

13 r year from 1994 to 2018 in the United States. Since 2008, HZO incidence declined in individuals youn

14 s, an increase of 267% and 294%, respectively, since 2009.

15 y, have supported the Ministry of Health (MOH) since 2011 to provide good quality contraceptive servi

16 or young adult men who have sex with men (MSM) since 2011.

17 In Ontario, Canada, since 2012, some hospitals discontinued contact precau

18 new infections among PWID, an increase of 115% since 2016.

19 , referred from other healthcare institutions, since 2016.

20 n marine ecosystems is a formidable challenge, since 40% of the detected compounds lack information r

21 e of thermal damage in the UHPH-treated musts, since 5-hydroxymethylfurfural was not detected.

22 s is the mechanistic pathway that they follow, since a deep knowledge of this mechanism may enable us

23 igin of these widespread phenomena is unclear, since a direct benefit is not always apparent.

24 ding pathogenic subpopulations is a challenge, since a distinction between physiological variation an

25 mg/L level was safety for oral administration, since a minor number of dead cells were found in red c

26 data fusion and PARADISe presented advantages, since a more comprehensive understanding of the relati

27 great importance for archaeological sciences, since a predominantly European haplogroup has been ide

28 clusion localization was not species specific, since a similar phenotype was observed with C. muridar

29 In particular, since a toxic element cannot have 'deficiency symptoms

30 autophosphorylation on Y130 in interdomain A, since a Y130E phosphomimetic form of Syk is predicted

31 ct of age at menarche on adult sleep duration, since age of menarche also affects obesity, our novel

32 rtually restricted to colocalization analyses, since an organizing core, without which NS cannot form

33 nd theorem and algorithm cannot be overstated, since an upper bound alone is not sufficient for deter

34 majority subunit of T4P) as a vaccine antigen, since antibodies directed against PilA are expected to

35 n alternative antigen for vaccine development, since antibodies to NS1 do not bind to the virion, the

36 vices raises the problem of how to power them, since batteries have not scaled down as much as the im

37 nclear how sequence encodes these differences, since biochemically distinct motors often have nearly

38 increased considerably over the past decades, since biodiversity within brown, red and green marine

39 r mass or through modulation of the afterload, since blood pressure was not changed.

40 and MHC-II affect antibody isotype switching, since both PIV-vaccinated B2m KO and MHC-II KO mice pr

41 ener color when compared to control treatment - since by default controls are not treated.

42 Additionally, since cancer cells are under selective pressure and ar

43 nd Q to human prostate carcinoma DU-145 cells, since catalase increased the survival of the cells sub

44 er mild conditions is a significant challenge, since cationic polymerization reactions are highly sen

45 verexpressing or knocking down protein levels, since changes in protein expression can be coupled via

46 ance should be at least partly size invariant, since changes only in scale do not affect an object's

47 le by mutagenesis and, possibly, by evolution, since chimpanzee cytomegalovirus UL148 retains CD58 bu

48 ous status may represent persistent infection, since Chlamydia genomes proliferated in the same tissu

49 tude is not linked to elevation of hemoglobin, since CMS(+) and CMS(-) individuals had similar levels

50 ltiarmed-bandit tasks offer an ideal test bed, since computational tools such as approximate Kalman f

51 inly in macerated forms, should be encouraged, since concentrations of riboflavin, vitamin E and flav

52 a hallmark model for vertebrate regeneration, since contrary to adult mammals, it is able to faithfu

53 therapy in patients with brain metastasis (BM) since contrast-enhanced MRI often remains inconclusive

54 quence of the virion infecting any given cell, since conventional techniques such as flow cytometry a

55 lved in light-dependent root growth promotion, since dark-grown seedlings have reduced root apical me

56 tive individuals into HCV-negative recipients, since de novo infection can be routinely cured.

57 episome persistence, they are not sufficient, since deletion of all internal LANA sequence renders L

58 core of NS is likely formed by SON and SRRM2, since depletion of SON leads only to a partial disasse

59 vatives are known to show several derivatives, since derivatization is incomplete as well as highly m

60 However, since DNA methylation is known to regulate transcripti

61 First, since e-skin will be exposed to prolonged stresses of

62 hondrial gene pool of ancient Umbri over time, since early Neolithic, including gene flows with centr

63 c considerations from other enzymatic systems, since enzyme can be lost to proteolytic degradation.

64 ubangstrom precision is, however, challenging, since epitaxially grown 2D layers exhibit complex rest

65 les between epithelial and mesenchymal tumors, since epithelial-mesenchymal transition is a key parad

66 p to explain tumor suppression encoded by p53, since erupting LINE1s produced acute oncogenic threats

67 This approach, however, is somewhat limiting, since everyday scenes are composed of complex images,

68 ociated health risks are somewhat paradoxical, since evolutionary pressures tend to favor energy-mini

69 a long sought fundamental question in science, since Faraday's 1857 work.

70 Moreover, since fenofibrate is an FDA-approved drug that has an

71 or designable structures remains a challenge, since few existing metrics capture high-level structur

72 estimation of sodium intake from cooked pasta, since food composition tables that do not reflect vari

73 aptation to risk could explain this behaviour, since foraging in fields is likely less risky under th

74 Also, since formaldehyde is the byproduct of biochemical rea

75 challenging from a computational perspective, since gene circuit models are complex systems with man

76 ars to increase the activity of EV biogenesis, since HCMV-infected fibroblasts have increased vesicle

77 scent probes based on small organic molecules, since higher selectivity for this organelle can be ach

78 75 to 282) on viral replicative capacity (VRC) since HLA-mediated reduction in VRC is a central mecha

79 In addition, since human skin proteins were also identified, this m

80 if large-scale product formation is an issue, since hydrogen is inexpensive and abundantly available

81 y angiography after a median of 7 days (4-8 d) since ICU admission and 12 days (9-16 d) days since th

82 This is counter-intuitive, since immune escape due to increased avidity (due itse

83 RS-CoV-2) in an older population is important, since increased incidences of illness and death from c

84 power for generating high confidence datasets, since information about phosphopeptide identity, site-

85 nsience as a measure of costs of reproduction, since initial detections are often associated with fir

86 ields provide an immediate option for storage, since injection infrastructure is in place and there i

87 l for functioning within dynamic environments, since interacting with a moving object (e.g., catching

88 erties across local regions in a protein; (ii) since interactions are specific between antibody-antig

89 arn predictive structural representations: (i) since interfaces are formed from multiple residues in

90 ideration of confounding factors is essential, since interventions for AF will be effective in reduci

91 ococcal disease, most notably in older adults, since introducing a 13-valent pneumococcal conjugate v

92 rican admixture nor Neanderthal introgression, since introgressed Neanderthal alleles are enriched in

93 ays a central role in Alzheimer's disease (AD), since it drives the cognitive decline.

94 he favored mechanism for catalytic activation, since it allows a significant reduction of the barrier

95 e vectorcardiography-derived QRS area is used, since it allows for a more detailed quantification of

96 Polymer design in this study is crucial, since it allows one to tightly control nanoparticle si

97 ntal form of eukaryotic cell-cell interaction, since it also occurs in multicellular organisms, where

98 emission is a particularly appealing prospect, since it avoids continuous exposure to treatment and p

99 comes even stronger in a multi-boundary world, since it can ameliorate many other planetary pressures

100 is mainly due to a maternal cytosolic defect, since it can be largely rescued by normal oocyte cytos

101 niaturized bioanalytical systems with enzymes, since it can provide information about the local enzym

102 e a major driver of the overall CS (OCS) rate, since it carries intrinsic risk of repeat CS (RCS) in

103 119, 276-293 (1928)] is not, since it converges too slowly.

104 k may have a substantial translational impact, since it describes a novel molecular pathway that coul

105 put processing of multiple scRNA-seq datasets, since it does not involve an expert curator, and it ca

106 alue anterior segment OCT in CCT measurements, since it is a non-contact method and correlate very we

107 However, since it is an invasive diagnostic procedure, complica

108 underlie the dissociative actions of ketamine, since it is during this phase that ketamine users repo

109 nother using gold standard clinical endpoints, since it is often not clear how much benefit each indi

110 ntify variants, the hypothesis is constrained, since it is typically assumed that the effect of the g

111 Usually, it is neglected, since it is very small when compared with thermal fluc

112 has been proposed as a potential drug target, since it maintains the balance between guanylate deoxy

113 apy efforts have focused on treating the lung, since it manifests the most significant life-threateni

114 -catalyzed [2 + 2 + 2] cycloaddition reaction, since it permits the formation of a wide range of high

115 idterm is not due to wrong or incomplete data, since it persists in error-free, synthetically produce

116 nd validation of candidate quantum processors, since it plays a key role in both performance assessme

117 ly aligned with our electrophysiological data, since it predicted discrimination only for numerosity,

118 le step of data analysis in all those studies, since it removes unwanted, non-biological variability

119 tegrative analysis is usually hard to conduct, since it requires several manual standardization steps

120 EC differs essentially from other condensates, since it takes place simultaneously at +/- k(min).

121 However, since it was developed primarily in animals, we lack i

122 valuation criterion in our numerical analysis; since it is the most fundamental property that can be

123 tant roles in brain development and functions, since its deficiency results in Angelman Syndrome (AS)

124 ay be generally irrelevant to the troposphere, since its initial oxidant generation is similar to str

125 However, since its introduction, high level vancomycin resistan

126 spectroscopy of organic and biological layers, since its refractive index is very similar to that of

127 t NSP4 might also be involved in this process, since knocking down its expression reduces VP7 trimeri

128 in alpha-synuclein-induced neurodegeneration, since knockout of parkin interacting substrate protein

129 t this is an underestimate of the true burden, since LD cases may be underdiagnosed.

130 bsence of microglia, uveitis does not develop, since leukocytes cannot gain entry through the blood-r

131 However, since limited analytical approaches are available for

132 Therefore, since little is known about the evolutionary dynamics

133 sociated, radiation-sensitive cell population, since long-bone removal or pre-transplant donor irradi

134 Indeed, since magnons are believed to exhibit attractive inter

135 epoxides generated in tumor cells and/or host, since many depended upon co-administration of a solubl

136 Finally, since many glycosylases are inhibited from working on

137 This process is complicated in cyanobacteria, since many, including Synechocystis sp. PCC 6803, cond

138 elds in medically relevant materials research, since microbial colonization of medical implants and d

139 of microhomology-mediated end joining mostly, since microhomologies between human and BKPyV genomes

140 ow reagent amounts and low energy consumption, since microwave irradiation is used only for sample ig

141 ond, we find evidence of a segregation effect, since mobility contraction is stronger in municipaliti

142 We believe that, since molecularly alike tumors could respond similarly

143 citly encode the context of the partner; (iii) since more data are available for general protein-prot

144 FPs bind transposable elements (TEs), however, since most TEs are inactive in humans it is unclear wh

145 standard means of diagnosis in the laboratory, since most viruses have a short period of replication,

146 These Abs typically have limited breadth, since mutations frequently arise in HA head epitopes.

147 y requires both in vivo and in vitro analyses, since Mycobacterium tuberculosis is a highly specializ

148 ent on the natural killer cell receptor (NCR1), since NCR1-deficient mice still inhibited mutant colo

149 tory profile unique to Abeta-burdened neurons, since neighboring glial cells did not express similar

150 However, since neurogenesis declines dramatically with age, it

151 ontinuous IL-4 production in the steady state, since NKT2 cells lost IL-4 production when intrathymic

152 However, since no biomarker for the identification of patients

153 vortices appear and disappear-is also unknown, since no changes, except for an intruder that visited

154 o be secondary to the motor skill acquisition, since no correlation was observed between neurophysiol

155 The single-vessel principle was fulfilled, since no further dilution or liquid transfer was requi

156 of their biosynthesis is not fully understood, since no gene has been identified that encodes plasman

157 o question the autophagy modulator cysteamine, since no rescue of mutant CFTR function was detected f

158 A-A*01:01pos could benefit from such products, since no T cells recognizing any EBV-derived peptide i

159 robably recalcitrant and more slowly degraded, since only highly specialized organisms can effectivel

160 h ALT-EJ and HDR, but via distinct mechanisms, since only the former is dependent on KU.

161 vize practices such as study pre-registration, since optimization requires a pre-specified analysis p

162 In addition, since oxylipids such as 5-, 12-, and 15-HETE are signa

163 ons in a S100B/RAGE/NFkappaB-dependent manner, since pentamidine, a S100B inhibitor, prevented 5-FU-i

164 pain-related conditions is also a possibility, since peppers contain capsaicinoids, carotenoids, phen

165 dependent on L. murinus-produced lactic acid, since pH neutralization of the conditioned medium abor

166 t Fe sources in Gram-positive human pathogens, since PiuA functions in the same way as SstD from Stap

167 In addition, since porphyrinoid-cyclodextrin systems comprise third

168 More importantly, since practically there are an unlimited number of bui

169 Finally, since prey-predator mixing is the key factor that regu

170 ional annotation of the protein is inadequate, since protein activities depend on posttranslational m

171 e sympathetic nerve activity (SNA) is unclear, since PVN leptin receptors (LepR) are sparse.

172 However, since radiation is prohibited in these systems, far-fi

173 otential determinants of host response switch, since RANKL imprint a tolerogenic phenotype in DCs, de

174 se-modifying treatments for synucleinopathies, since RBD represents an early prodromal stage of synuc

175 rived IL-13 was sufficient for RSV-driven AHR, since reconstitution of wild-type ILC2 rescued RSV-dri

176 However, since reducing hyperfine fields sharpens the Zeeman pe

177 uring the accuracy and reliability of results, since repeatability has been a problem in studies util

178 ffective in the case of multiple amino groups, since retention is stabilized through interaction with

179 NAs regulate the subcellular location of Ro60, since Ro60 is reduced in the cytoplasm and increased i

180 xylem production compared with the wild type (since secondary walls were thinner).

181 eir differential responses to the environment, since several long noncoding RNAs (lncRNAs) are known

182 However, since several oxidation products display the same mass

183 Furthermore, since several PFAS are expected to be highly present i

184 probably due to lack of molecular resolution, since shifting the third strand by a single nucleotide

185 hijacking a function of a cellular chaperone, since simian immunodeficiency virus T antigen was prev

186 s has advantages over conventional approaches, since simple modifications can be applied to recover a

187 ity are theorized to amplify sexual selection, since some males attract multiple mates or copulate wi

188 s prediction accuracy for a wider application, since specific interaction features are inevitably obs

189 ometry method for multiple allergen detection, since specificity, robustness and sensitivity of the o

190 om the activity in this population of neurons - since speed and direction must often be combined to p

191 h of practical spaced seeds to be constrained, since storing spaced seeds can be costly.

192 rin (A-PRF) has further confused many readers, since studies have not always used centrifugation para

193 actors and/or mitochondrial dynamics/function, since Sub2 controls mRNA splicing and Mdm30 regulates

194 es, 'value' was coupled to a behavioural goal, since subjects had to choose the item they preferred.

195 ompatible thin film sorbent coatings are used, since such materials have been commonly applied as mea

196 ontrol CD4(+) T helper 2 (Th2) cell responses, since suppressive and activating roles have been repor

197 l heteromers also applied to the steady-state, since sustained Btnl expression is required to maintai

198 However, since thalassemia is endemic in many under-developed c

199 onfirms the concept of "biological invariance" since the altered pathways should be independent of th

200 roups despite both having similar HbA(1c) (~8%) since the end of DCCT, when 96% of participants enter

201 esulted in the release of 11-21 Tg CO(2) (-eq) since the 1950s, increasing cumulative CO(2) emissions

202 and nation of Samoa (2016 population, 195 979) since the 1960s and has persisted through 2019, despit

203 y, the "Latest Amber Bioinclusions Gap" (LABG) since the late Miocene to the end of the Pleistocene i

204 in Bahamian biodiversity (including endemism) since the Late Pleistocene.

205 species and the disparate timescales involved, since the aggregating proteins are simultaneously the

206 The results extend theories of surface growth, since the behavior is consistent with surface evolutio

207 resistance of I/LnJ BMDMs was specific to MNV, since the cells supported infection of other viruses c

208 Moreover, since the classical 12/23 rule for the V(D)J recombina

209 ablish a model of spurge chromosome evolution, since the common paleopolyploid event occurred before

210 mall scale and large scale brewed beer groups, since the content of these components can vary between

211 In Iceland, since the detection of the first macrolide-resistant i

212 e to adjourn due to changes in fluid rheology, since the drilling fluids may lose their effectiveness

213 predominantly performed via 2D static images, since the embedding of interactive 3D structures in we

214 information about how to navigate the search, since the encountered surrounding is composed of prote

215 he role of the centrale in the hominoid wrist, since the fusion of this bone with the scaphoid is amo

216 containing 3 (NLRP3) inflammasome activation, since the genetic ablation and pharmacological inhibit

217 xperiments using genetically modified animals, since the genotypic composition of the social environm

218 Furthermore, since the ILP formulations for the conserved versions

219 terial pressure response to the initial fluid, since the implications include decreased arterial tone

220 noids, esters and chlorophylls were evaluated, since the influence of esterification on bioaccessibil

221 d to be more stable than the dimer in toluene, since the latter more readily forms direct Li/Cl inter

222 or informing cancer progression and therapies, since the lipid content and macromolecular cargo of EV

223 tRNAs is the essential function of the enzyme, since the majority of 5'-immature tRNAs can be aminoac

224 Moreover, since the mapping of error-prone reads to ETRs remains

225 n other bacteria hint at additional functions, since the most conserved Y RNA contains a domain that

226 However, since the mouse has a wide repertoire of motor actions

227 the analysis of standard reference materials, since the obtained data were in close agreement with r

228 th crisis of this generation and, potentially, since the pandemic influenza outbreak of 1918.

229 e very close to the laser acceleration source, since the particle density within the bunch is strongl

230 tainty space in phenotype prediction problems, since the probabilistic parameterization of the uncert

231 s catalyzed by sub-nanometer Pt or Pd species, since the reactivity control is shifted toward subtle

232 directions rather than the weights themselves, since the relevant function underlying classification

233 ikely a conserved feature of the metazoan SAC, since the relevant PLK1 and PP2A-B56 binding motifs ha

234 Overall survival was not analyzed, since the required number of events to trigger the fin

235 cts as a reporter of leaving-group reactivity, since the ring-opened product is obtained under polar

236 rane retention allowed for enzyme reusability, since the same conversion yield was obtained in three

237 allows working with increased chemical spaces, since the same elements can take on a large number of

238 they are not immune to the risk of explosion, since the sealing structure adopted by current batteri

239 mic interactions are particularly challenging, since the technique requires excellent photon statisti

240 t a particular challenge for these algorithms, since the temporal ordering of cells is not directly o

241 Finally, since the training needs to be performed only once, th

242 ed the impact of manganese (Mn) on As removal, since the two often co-occur in groundwater.

243 Furthermore, since the U.S. electric grid is rapidly changing, we u

244 In materials science, since the use of nitroxides often limits the signal en

245 Finally, since the way machine learning algorithms are reported

246 : Since their discovery, neutrophil extracellular traps

247 rates of HZ and post-herpetic neuralgia (PHN) since their introduction.

248 vasive serogroup B meningococcal disease (IMD) since their licensure in 2013 and 2014.

249 e of opportunities for potentiometric sensors, since their combination of robustness, simplicity of o

250 tional ensembles of IDPs is of great interest, since their conformational ensembles are the link betw

251 ven-dissipative exciton-polariton condensates, since their non-equilibrium nature is predicted to sup

252 thought to represent the GnRH pulse generator, since their oscillatory activity is coincident with LH

253 Rationale: Since their approval, there has been no real-world or

254 at advantage by providing numerical solutions, since theoretical distributions of test statistics are

255 requires LN biopsy for pathologic evaluation, since there are no clinical imaging approaches that ca

256 However, since there has been a lack of direct measurements cha

257 ry team is essential to care for DBA patients, since there is a significant emotional burden related

258 For in-vivo (intramuscular) experiments, since there is not a gold standard for measuring pO(2)

259 This is especially problematic for inversions, since there is typically no gain or loss of DNA.

260 other populations, but for age and sex trends, since there was a majority of younger women.

261 al pressure drop and boundary layer thickness, since these all factor in to jet stability and collima

262 However, since these bones are highly fragmented and anthropoge

263 allenging in the present best CQD solar cells, since these employ a p-type hole-transport layer (HTL)

264 enerated in the context of helminth infection, since these large pathogens often shed their outermost

265 in the application of such materials at scale, since these two transport phenomena (charge and mass t

266 ted herein are immunogenic peptides (epitopes) since they induced the production of cytokines by PBMC

267 generally less tolerant to cold temperatures, since they are confined to attacking hosts pupating an

268 s investigated as a model bioelectrosynthesis, since they are high-value intermediates in statin synt

269 y for samples prepared from compressed H(2) S, since they are inevitably contaminated with H-depleted

270 nt on SA synthesis and SA perception pathways, since they are lost in isochorismate synthase1/salicyl

271 annerella forsythia, by using in silico tools, since they are potentially associated with inflammator

272 unning a lab we do not think about calamities, since they are rare events for which we cannot plan wh

273 a nanoparticles (DDSNPs) are of high interest, since they can offer several advantages in terms of se

274 can be considered as an environmental concern, since they can retain part of the bioactivity of the p

275 gae are an attractive option for the research, since they can synthesize a group of secondary metabol

276 cteria seem to exploit host cell trogocytosis, since they can use it to spread from cell to cell.

277 les importance in the projection (VIP) values, since they contribute mainly to the discrimination of

278 nV-activated macrophages were different of M1, since they did not produce pro- and anti-inflammatory

279 idates for development of H(2)O(2) biosensors, since they exhibit a good dynamic response range (1-20

280 7 signaling pathway and TNF signaling pathway, since they had 73 potential target genes regulated by

281 lishment and persistence of the HIV reservoir, since they harbor high levels of HIV/SIV, increase the

282 contributors to the HIV/SIV latent reservoir, since they harbor high levels of HIV/SIV; reverse CD4(

283 In this work, we focused on protein antigens, since they induce the largest antibody changes, and pr

284 is less likely to identify infected children, since they often experience milder disease than adults

285 Gold nanostars were used as SERS nanotags, since they provided a better response than nanorods or

286 These effects were mediated by beta-cell M3Rs, since they were absent in mutant mice selectively lack

287 However, since this outcome may overestimate the risk for SCD,

288 t of an enzyme that activates thyroid hormone; since this discovery, the relevance of selenium to thy

289 dwide is outpacing our abilities for analysis, since to date, such datasets have been analyzed in a h

290 9)Zr-immuno-PET will need to move beyond SUVs, since total uptake may contain a significant non-targe

291 or potential vanilloid cation channels (TRPVs) since TRPV1/TRPV4 antagonism blocked the febrile Th2 s

292 eterozygosity events is an attractive concept, since tumor cells may lack enzymatic activities presen

293 Furthermore, since tungsten does not undergo room-temperature alloy

294 However, since typical chemical routes towards activating RNA s

295 iduals are analyzed, which can increase power, since unaffected family members can be susceptibility

296 CAG repeat in HTT [reference: (CAG)n-CAA-CAG], since variants within this region have been previousl

297 upon the maintenance of virological remission, since viral load is found to be the most important fac

298 ression of HIV upon SP treatment interruption, since virus rapidly rebounds when XPB reemerges; howev

299 t with the control of internal joint stresses: Since VM and VL produce opposing mediolateral forces o

300 ptomic changes may belong to the same circuit, since we observed coordinated transcriptomic shifts ac