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1 We directly define modifications on molecules, thereby ensuring 100% chemical validity.
2 ding sites in its 3' untranslated region (UTR), thereby ensuring a dual control of unwanted cell deat
3  for Cig2 destruction during anaphase and G(1), thereby ensuring a spike pattern of Cig2 levels, peak
4 o allosterically activate Lon to degrade DnaA, thereby ensuring a cell-cycle arrest.
5  a maximal amount of antigen in a single dose, thereby ensuring a clonal burst that involves the larg
6 ctroporation and assessment biosensing system, thereby ensuring a consistent and reliable means of ac
7 tae membrane with the inner boundary membrane, thereby ensuring a contiguous inner membrane.
8 s thought to mitigate recombination reactions, thereby ensuring a high quantum yield of water oxidati
9 and other partial reaction steps of the cycle, thereby ensuring a high rate of Ca(2+) transport under
10 ly maintain the low basal expression of SHLD1, thereby ensuring a proper balance between end protecti
11 ppress parasitic Mn migration and dissolution, thereby ensuring a reversible electrochemical cycling.
12 output between both halves of the spinal cord, thereby ensuring a symmetrical pattern of locomotor ac
13  that do not match the codon of messenger RNA, thereby ensuring accuracy in translation of the geneti
14 romosome biorientation precedes SAC silencing, thereby ensuring accurate chromosome segregation.
15 at APC/C(Cdh1) controls the stability of TPX2, thereby ensuring accurate regulation of the spindle as
16 unoglobulin heavy chain or TCRbeta chain loci, thereby ensuring allelic exclusion.
17 selective disposal of proteins and organelles, thereby ensuring amino acid recycling.
18 e also find that RDE-8 promotes RdRP activity, thereby ensuring amplification of siRNAs.
19 ork's ability to capture fine-grained details, thereby ensuring an effective improvement in segmentat
20  also necessary to maintain a functional PRC1, thereby ensuring appropriate levels of repressive H2Au
21 neural progenitors in the embryonic hindbrain, thereby ensuring appropriate neural circuit formation,
22  classes of neuronal processes within the OPL, thereby ensuring appropriate ribbon synapse formation,
23 riptional control of mevalonate pathway genes, thereby ensuring balanced biosynthesis of cholesterol
24 lasma membrane and regulates turnover of LpxC, thereby ensuring balanced biosynthesis of LPS and phos
25 cal force, PAK2 is protected from proteolysis, thereby ensuring cell survival.
26 eviations from physiological set-point levels, thereby ensuring cholesterol homeostasis.
27 ing YAC-specific, unique, recombinogenic ends, thereby ensuring co-integration of the markers.
28 trations with the efflux of acrosomal calcium, thereby ensuring complete fusion of the large acrosoma
29 rgy source without problematic waste build-up, thereby ensuring consistent performance over time.
30 ing of receptor/transcriptional DNA complexes, thereby ensuring continued hormone response.
31 y to silence the key EBV lytic switch protein, thereby ensuring continued viral latency in B lymphocy
32  progression and repress V gene accessibility, thereby ensuring coordination of proliferation with im
33 inker joins the recognition and lysis domains, thereby ensuring correct folding of the individual dom
34 ntly to clear the ER from metaphase chromatin, thereby ensuring correct progression through mitosis a
35 e, which operates independently of references, thereby ensuring cost-efficiency by circumventing the
36 ogous end joining (NHEJ) pathway is inhibited, thereby ensuring crossover formation and accurate chro
37  proteins directly interact with SERK kinases, thereby ensuring effective BRI1-SERK interaction and t
38 ining cochlear partition mechanical impedance, thereby ensuring effective transfer of OHC isometric f
39  nuclear import signals within the PABPC RRMs, thereby ensuring efficient cytoplasmic retention of th
40 in the nucleus during zygotic DNA replication, thereby ensuring efficient DNA methylation reprogrammi
41 n of replication and the host cell chromosome, thereby ensuring efficient partitioning of viral genom
42 f up-stream and downstream signaling proteins, thereby ensuring efficient propagation of signals carr
43 he avidity and longevity of Vpr-Gag complexes, thereby ensuring efficient Vpr packaging.
44 ay be activated in response to meiotic errors, thereby ensuring elimination of chromosomally abnormal
45 ins intact despite near-complete delithiation, thereby ensuring excellent cycling stability for 4.7 V
46  remyelinate or re-ensheath regenerated axons, thereby ensuring functional recovery.
47 e breaks and restore broken replication forks, thereby ensuring genome stability and cell survival.
48 ls transposon expression in animal germ cells, thereby ensuring genome stability over generations.
49 ation, which prevent aberrant fork processing, thereby ensuring genome stability.
50 rigin firing and replication fork progression, thereby ensuring genome stability.
51 and terminates at their polyadenylation sites, thereby ensuring global co-directionality of transcrip
52  breeding site with the local onset of spring, thereby ensuring gosling benefit from the peak in nutr
53 on through the G-rich lagging strand telomere, thereby ensuring high fidelity telomere replication.
54 nslationally repress cyclin CLB3 in meiosis I, thereby ensuring homologous chromosome segregation.
55 ins (SPs) to initiate procapsid (PC) assembly, thereby ensuring incorporation of only one portal ring
56 lps to maintain MYC phosphorylation at Ser 62, thereby ensuring its cooperation with oncogenic KRAS i
57 tuberculosis can evade host defense processes, thereby ensuring its survival and pathogenesis.
58 ulted in nuclear translocation of p65NFkappaB, thereby ensuring its survival.
59  spatiotemporal pattern of guidance signaling, thereby ensuring neural projections occur with high fi
60 itochondrial Ca(2+) uniporter are unavailable, thereby ensuring neuronal metabolic flexibility.
61 egulated p53 tetramerization occludes its NES, thereby ensuring nuclear retention of the DNA-binding
62 ian system regulates all biological processes, thereby ensuring optimal function at the appropriate t
63 novo centriole formation before fertilization, thereby ensuring paternal inheritance of the centrosom
64  fusogenic effectors at the site of infection, thereby ensuring pathogen-directed responses during in
65 to the emerging daughter during cell division, thereby ensuring progeny viability.
66 ed RhoGTP levels are achieved in late mitosis, thereby ensuring proper cell division.
67 iptional level to level out these differences, thereby ensuring proper cell number homeostasis.
68 centriole stability during and after assembly, thereby ensuring proper centriole number.
69 to maintain proper Bre1 and H2BK123ub1 levels, thereby ensuring proper control of gene expression.
70 for adequate expression of maternal behaviour, thereby ensuring proper development of the offspring.
71 llectively control actin filament homeostasis, thereby ensuring proper execution of actin-dependent p
72 e flagellum-associated hook complex structure, thereby ensuring proper flagellum positioning and atta
73 on within a limited developmental time window, thereby ensuring proper forebrain development.
74 mpairs the negative regulatory role of StBPA1, thereby ensuring proper immune signaling.
75  of the Golgi apparatus and neuronal polarity, thereby ensuring proper neuronal migration and differe
76 replicated chromosomes to the mitotic spindle, thereby ensuring proper sister chromatid separation du
77 stem-like cell type in Caenorhabditis elegans, thereby ensuring proper temporal cell fate patterning.
78 G, which function similar to an OR logic gate, thereby ensuring Qrr1 is expressed during colonization
79 related mitofusins in the tethering mechanism, thereby ensuring rapid and high fidelity Ca(2+) signal
80 y compared to conventional biological enzymes, thereby ensuring reliable sensor operation.
81 o carefully control and trace source material, thereby ensuring results are accurate, complete, and a
82 ation of deuterium atoms on the aromatic ring, thereby ensuring retention of the isotope label during
83 and enhanced inhibition in the null direction, thereby ensuring robust directional selectivity.
84 xhibit an equally high c-Fos expression level, thereby ensuring robustness in IL-2 response within th
85 le extrinsic pathways that favor self-renewal, thereby ensuring robustness of neuronal fate transitio
86 ic GTP hydrolysis of the GTP-binding proteins, thereby ensuring signal termination.
87 romeric heterochromatin is to attract cohesin, thereby ensuring sister centromere cohesion and proper
88  of cohesin specifically onto chromosome arms, thereby ensuring sister chromatid cohesion and proper
89  catalytic domains to the ubiquitination site, thereby ensuring site-specific ubiquitination of NEMO.
90 ract upon guest binding, as studied by VT-NMR, thereby ensuring strong binding of both small and larg
91  His leads to strong binding of the Pd center, thereby ensuring substantial stability of the system.
92  of controlling adhesion at the leading front, thereby ensuring successful tissue fusion.
93 tes rapid regulation of inflammatory pathways, thereby ensuring sufficient but not excessive response
94 tant gene in all diseased photoreceptor cells, thereby ensuring sufficient transduction efficiency.
95 ase promoting complex (APC)-proteasome system, thereby ensuring temporal control of late mitotic even
96 nteracts the CHD7-induced chromatin expansion, thereby ensuring temporally and spatially controlled '
97        The degradation of Skp2 stabilizes p27, thereby ensuring TGF-beta-induced cell cycle arrest.
98 s array of large-capacitance tunnel junctions, thereby ensuring that all superconducting islands are
99 ns is subject to multiple modes of regulation, thereby ensuring that animals exhibit the responses mo
100 yo along the correct developmental trajectory, thereby ensuring that asymmetric division is robust to
101 ons and positions of the arms of the junction, thereby ensuring that binding is selective for branche
102 se PRIMPOL to facilitate gapped DNA synthesis, thereby ensuring that cells do not accumulate replicat
103 ry surface contact to capture extending axons, thereby ensuring that combinatorial codes of positive
104 CO HR outcome near the centers of chromosomes, thereby ensuring that COs form predominantly at off-ce
105 o simplify the process of metadata annotation, thereby ensuring that data leave a lasting, impactful
106 te an Aurora B-mediated abscission checkpoint, thereby ensuring that daughter cells are generated onl
107 tive guidance receptors on postcrossing axons, thereby ensuring that decussated axons are selectively
108 ose the epithelium controls mesoderm adhesion, thereby ensuring that embryos and, by extension, adult
109 cross all phases of the HIV prevention market, thereby ensuring that individuals can realise their ri
110 initiate BDNF signaling through synaptic TrkB, thereby ensuring that learning will trigger neurotroph
111 nase to boost Cdc25 activity and inhibit Wee1, thereby ensuring that mitotic commitment is a bistable
112 ween conservation practice and policy targets, thereby ensuring that ongoing investment in biodiversi
113 ls to restrict initiation to normal promoters, thereby ensuring that only appropriate mRNAs are synth
114 bits growth of crystals remaining in solution, thereby ensuring that only crystals within fibrils gro
115 etwork activation with cell cycle progression, thereby ensuring that PAR proteins respond specificall
116 ue but reduce variance in cumulative outcomes, thereby ensuring that resources remain above a critica
117 gregating, recruit the highest levels of Mad2, thereby ensuring that SAC activation is proportionate
118 ruited to the surface of the developing spore, thereby ensuring that SpoIVA polymerization only occur
119 f the INTERGROWTH-21st standard were excluded, thereby ensuring that the charts depict body compositi
120 tationally aligns along this axis of polarity, thereby ensuring that the cleavage plane is positioned
121 is-Hin contacts limit rotational processivity, thereby ensuring that the DNA strands religate in the
122 ry traces after cortical memory consolidation, thereby ensuring that the hippocampus is continuously
123 ow to invade middle and upper cortical layers, thereby ensuring that the location of invading interst
124 ontrols T cell cross-reactivity for pMHCI Ags, thereby ensuring that the peripheral T cell repertoire
125 ation of 10, 25 and 50 mg/kg of maslinic acid, thereby ensuring that the procedure is appropriate for
126 d function as internal guides to recruit ClpX, thereby ensuring that the tetrameric complex is a high
127 to inhibit centriole separation at meiosis II, thereby ensuring that the zygote inherits the appropri
128 nriched during the G1 phase of the cell cycle, thereby ensuring that TIRR-dependent inhibition of 53B
129 ivates unwinding by coupling these activities, thereby ensuring the downstream formation of single-st
130  of information relating to executive control, thereby ensuring the efficient allocation of cognitive
131  composite active site at the dimer interface, thereby ensuring the electrostatic and/or structural i
132 olved to counteract these detrimental effects, thereby ensuring the faithful inheritance of G4-contai
133  that recognize the same transmembrane degron, thereby ensuring the fidelity of protein deployment to
134 rred ligand relative to the natural substrate, thereby ensuring the fidelity of removing highly react
135 m generating more than one functional H chain, thereby ensuring the formation of a unique pre-BCR.
136 cillations might be to activate CRAC channels, thereby ensuring the generation of spatially restricte
137 romosomal content generated by mitotic errors, thereby ensuring the genomic integrity of gametes.
138 d-directed, TGF-beta-guided tubule elongation, thereby ensuring the looped morphology characteristic
139 nium adjuvants potentiate the immune response, thereby ensuring the potency and efficacy of typically
140 ll division, and cell growth with one another, thereby ensuring the precise spatial and temporal cont
141 signals that modulate nuclear gene expression, thereby ensuring the proper assembly of the photosynth
142 xygen to a specific region of the active site, thereby ensuring the regio- and stereospecificity of p
143 se to physiological and developmental signals, thereby ensuring the robustness of genetic regulatory
144 to maintain the localization of active myosin, thereby ensuring the spatial control of concerted cont
145 particular closed conformation of the complex, thereby ensuring the stability of the RNA polymerase w
146 nzyme to fine-tune iMet processing of key RPs, thereby ensuring the structural integrity and function
147 ommunication, and sequence encoding/retrieval, thereby ensuring the successful formation and/or retri
148 very in areas affected by severe disturbances, thereby ensuring the sustainability of ecosystem servi
149 endent TCR rearrangements during TCR revision, thereby ensuring the utility of the postrevision reper
150 crystallographic fragment-screening campaigns, thereby ensuring their accessibility for advancing res
151 a coli converts plasmid multimers to monomers, thereby ensuring their correct segregation at cell div
152 o be used to target other proteins to the INM, thereby ensuring their proper and timely localization
153 omains of multipass substrates in the cytosol, thereby ensuring they adopt the correct topology and e
154 s the extent of transcription into the operon, thereby ensuring tight control of cellular NusA levels
155 ukBEF clusters and associated topisomerase IV, thereby ensuring timely chromosome unlinking and segre
156 y preventing APC/C-Cdc20-mediated degradation, thereby ensuring timely mitotic entry.
157 Mn accumulation in the cytoplasm and apoplast, thereby ensuring tolerance to high Mn in the root envi
158  niche support a bloom of Salmonella serovars, thereby ensuring transmission of the pathogen to the n
159 r their needed surgical biopsy and/or removal, thereby ensuring unmissed disease to prevent recurrenc
160 xtra centrosomes into pseudo-bipolar spindles, thereby ensuring viable cell division.
161  interact with multiple transcription factors, thereby ensuring viral replication in a variety of cel

 
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