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1 and Toll-like receptor (TLR) signals in vitro, thereby promoting a B cell-intrinsic break in toleranc
2 tional activator of UCP1 as well as PGC1alpha, thereby promoting a BAT program.
3 uence of oxidative-induced structural changes, thereby promoting a gain of function in integrin bindi
4  macrophages leads to enhanced JNK activation, thereby promoting a phenotypic switch from an anti-inf
5 ances plasmin-mediated activation of TGF-beta, thereby promoting a profibrosing phenotype.
6 o function by limiting translation initiation, thereby promoting a ribosome-free mRNA that is targete
7 ous, proinflammatory TGFBR2 signaling in SMCs, thereby promoting AAD formation.
8 roxyvitamin D3 inhibits TCR-driven activation, thereby promoting abatacept sensitivity.
9 he sensitivity to punishment in LgA rats only, thereby promoting abstinence.
10 ives mast cells and basophils into exocytosis, thereby promoting allergic and potentially anaphylacti
11 a6beta4 integrins and with other tetraspanins, thereby promoting alpha3beta1 and alpha6beta4 associat
12 myloidogenic conformations of AL light chains, thereby promoting amyloid formation, whereas chondroit
13 ed PPARgamma and enhanced PPARbeta expression, thereby promoting an activated phenotype.
14 from other APCs that cause negative selection, thereby promoting an overall larger number of survivin
15 invasion, in part, by hyperactivation of mTOR, thereby promoting and sustaining protein synthesis und
16 l-associated gammadelta T-cell subpopulations, thereby promoting angiogenesis and cancer development.
17 and MMP release in the tumor microenvironment, thereby promoting angiogenesis and metastasis.
18 is may target AUF1 destruction by proteasomes, thereby promoting ARE mRNA stabilization.
19 stic pattern increases APD dispersion in LQT2, thereby promoting arrhythmia.
20 naling cascade in a ligand-independent manner, thereby promoting arteriogenesis in diseased tissues.
21  them from the mRNA cap binding protein eIF4E, thereby promoting assembly of the eIF4E.eIF4G complex.
22 e cooperate to deplete cIAP1, cIAP2, and XIAP, thereby promoting assembly of the ripoptosome, a RIP1/
23 d its accumulation by artery wall macrophages, thereby promoting atherosclerosis.
24  occurrence of EBW during atrial fibrillation, thereby promoting atrial fibrillation persistence.
25 to the C6-hydroxyl of MurNAc in peptidoglycan, thereby promoting attachment of wall teichoic acid (WT
26 at TPL2 mediates TAK1 axis of IL-17 signaling, thereby promoting autoimmune neuroinflammation.
27 of T lymphocytes toward T-helper (Th)17 cells, thereby promoting autoimmunity in systemic lupus eryth
28 ty of neurotrophic factors in the lesion site, thereby promoting axonal regeneration and locomotor fu
29 tion of RPS3 Ser209 and blocked RPS3 function, thereby promoting bacterial colonization and diarrhea
30 servoirs for intracellular S. aureus survival, thereby promoting bacterial resistance to antibiotic t
31 red gene that controls an ancestral regulator, thereby promoting bacterial virulence.
32 (ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting beta-catenin destabilization.
33 stimulation decreases LAMTOR/BORC association, thereby promoting BORC- and Arl8b-dependent lysosomal
34 echanical activation in proprioceptive organs, thereby promoting Ca(2+) influx, which is required for
35 tion of inhibitor of apoptosis proteins (IAPs), thereby promoting cancer cell death.
36 ds to and enhances the kinase activity of Akt, thereby promoting cancer progression.
37 beta-catenin-TCF/LEF-mediated transactivation, thereby promoting cancer stemness.
38 for enhancing the carbon corrosion resistance, thereby promoting catalyst stability.
39  net negative charge of the bacterial surface, thereby promoting cationic antimicrobial peptide resis
40 Unc5A-D) interact with FLRT proteins (FLRT1-3), thereby promoting cell adhesion and repulsion, respec
41 ellin with CAV1 stimulated integrin recycling, thereby promoting cell adhesion.
42 it from cleaving a cell surface-bound adhesin, thereby promoting cell adhesion.
43 thin lipid rafts to prevent Notch1 activation, thereby promoting cell proliferation and tumor formati
44 RP1)-DNA complexes trapped by PARP inhibitors, thereby promoting cell survival after drug treatment.
45 DLBCL) to drive aberrant NF-kappaB activation, thereby promoting cell survival and propagation.
46  a metabolic advantage to photoreceptor cells, thereby promoting cell survival.
47 uced apoptosis and by inhibiting RB1 function, thereby promoting cell-cycle progression.
48 n by increasing DeltaNp63alpha protein levels, thereby promoting cellular proliferation.
49 e transcription of the tumor suppressor TAp63, thereby promoting cellular senescence and blocking ski
50 is is to disrupt the Sgo1-cohesin interaction, thereby promoting centromeric cohesion de-protection a
51 y enhancing the interaction of CheY1 and CheA, thereby promoting CheY1-P dephosphorylation, which res
52 base excision repair of endogenous DNA damage, thereby promoting chromosome stability in normal human
53 or macrophage retention at inflammatory sites, thereby promoting chronic inflammation and disease dev
54 f hepatic macrophages toward the M1 phenotype, thereby promoting chronic liver injury and fibrosis pr
55 rcadian transcriptional and cytosolic rhythms, thereby promoting circadian oscillations to integral p
56 elical conformations of the bulge nucleotides, thereby promoting coaxial stacking of helices.
57 e Rac and RhoA activation in epithelial cells, thereby promoting complex functions such as sheet migr
58 rosine kinase Fyn and the exchange factor Vav, thereby promoting conjugate formation between NK cells
59 t signals to activate the FAK/p130Cas pathway, thereby promoting CRC cell migration, invasion and met
60  by blocking the ubiquitin-proteasome pathway, thereby promoting CRC development.
61 g via the Notch and Wnt/beta-catenin pathways, thereby promoting crypt regeneration, and also repleni
62 d N-terminal RxxxR motif and the Cupin domain, thereby promoting CuxR dimerization and DNA binding.
63 7 functions by modulating tubulin acetylation, thereby promoting daughter centriole stability.
64 pineal prevents this Tcf7l2-dependent process, thereby promoting dHbl differentiation.
65 neural progenitor markers Geminin and Foxd4l1, thereby promoting differentiation.
66  balance toward a proinflammatory state in MS, thereby promoting disease activity and progression.
67 ectly interacts with and deubiquitinates CtIP, thereby promoting DNA end resection and HR.
68  and SUV4-20H, to enhance its K20 methylation, thereby promoting DNA synthesis and repair.
69 r minichromosome maintenance complex proteins, thereby promoting DNA synthesis complex assembly and c
70  complex to sites of DNA double-strand breaks, thereby promoting early ATM checkpoint responses and h
71 ty of the D-loop to dissociation by helicases, thereby promoting ectopic telomere formation.
72 istone H3 acetylation and chromatin structure, thereby promoting efficient DNA repair of UV-induced l
73 oordinates resection and nucleotide synthesis, thereby promoting efficient HR repair and genome stabi
74 esicles likely become tethered while they bud, thereby promoting efficient retrograde transport.
75 n together to protect Hrs from ubiquitination, thereby promoting EGFR intraluminal sorting.
76 y increases bile salt exporter protein levels, thereby promoting enterohepatic bile acid recirculatio
77 quired for ER to bind both p38gamma and c-Jun, thereby promoting ER relocation from ERE to AP-1 promo
78 embly of the LIG4/XRCC4 complex at DNA breaks, thereby promoting error-free NHEJ.
79  within-population phenotypic differentiation, thereby promoting evolutionary divergence.
80 b of the holoenzyme and weakens its integrity, thereby promoting exchange.
81  repression of key stem cell identity factors, thereby promoting exit from stemness.
82 ormation competent for 3'-splice site docking, thereby promoting exon ligation.
83 the pre-mRNA might bring exons 6 and 9 closer, thereby promoting exon skipping.
84 eta1 inhibits expression of the miR-29 family, thereby promoting expression of ECM components.
85 active AR for ubiquitin-dependent degradation, thereby promoting expression of select AR target genes
86 lating DNA damage-induced EZH2 downregulation, thereby promoting EZH2-mediated gene silencing and can
87 lates the Ca(2+) affinity depending on the pH, thereby promoting fast ligand release.
88  Bin3's role is to bind and stabilize 7SK RNA, thereby promoting formation of a repressive RNA-protei
89 he enzyme by inducing a conformational change, thereby promoting formation of the persulfide intermed
90  and mechanical properties of actin filaments, thereby promoting fragmentation of partially decorated
91 formation modes and store more elastic energy, thereby promoting fragmentation.
92 excessive consumption of glucose and fructose, thereby promoting further weight gain.
93 ircumference and heart rate responses to SAHC, thereby promoting g-tolerance.
94 riving force for long-term silencing of BRCA1, thereby promoting genome instability and tumor progres
95 r destabilization and translational silencing, thereby promoting germ cell development.
96 S increased the numbers of viable tumor cells, thereby promoting glioma cell proliferation.
97 ation and Akt substrate AS160 phosphorylation, thereby promoting Glut4 membrane translocation.
98  factor 1alpha (Hif1alpha)-independent manner, thereby promoting glutamine-based anaplerosis.
99 t redirects blood flow away from the aneurysm, thereby promoting growth of a new endothelial lining a
100 to modulate autocrine Hedgehog (Hh) signaling, thereby promoting GSC lineage differentiation.
101 117 accelerates intrinsic nucleotide exchange, thereby promoting GTP loading.
102 teins that repress IMD activity in the midgut, thereby promoting gut hyperplasia.
103 zes protonated sites on the protruding chains, thereby promoting H(+) retention on the protein.
104 a dopamine imbalance in striatal compartments, thereby promoting habits and vulnerability to maladapt
105  I to resolve a long double-flap intermediate, thereby promoting hairpin removal and preventing TNR e
106 can provide a buffer against this time famine, thereby promoting happiness.
107 nfiltration of immune cells upon liver injury, thereby promoting hepatic inflammation and fibrosis.
108 damage responses and hepatocyte proliferation, thereby promoting hepatocarcinogenesis in mice.
109 damage responses and hepatocyte proliferation, thereby promoting hepatocarcinogenesis.
110 ircadian clocks to daily environmental cycles, thereby promoting homeostasis.
111 iquitinates the Fanconi anemia protein FANCD2, thereby promoting homologous recombination and DNA cro
112 nd regulating ATR-Rad9/ATR-ETAA1 interactions; thereby promoting homologous recombination (HR) and PA
113 ha and ubiquitinates HP1alpha at residue K154, thereby promoting HP1alpha degradation through the aut
114 ly transmit coastally perturbed change inland, thereby promoting ice-sheet instability.
115 ntigens enhance ILC2-derived IL-13 production, thereby promoting IgE-mediated experimental food aller
116 val, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors.
117 histocompatibility complex class II molecules, thereby promoting immunity.
118 ges and, in turn, diminishes SIRT3 expression, thereby promoting inflammation.
119 ory and immune responses to pancreatic islets, thereby promoting inflammatory destruction and immune
120 al cells (PECs) invade glomerular capillaries, thereby promoting injury and kidney failure.
121 spase-1-dependent interleukin-1beta secretion, thereby promoting interferon-gamma production and T he
122 th neighboring ERGIC membranes upon uncoating, thereby promoting interorganellar cargo transport.
123 ng in the secretion of pro-fibrotic cytokines, thereby promoting interstitial fibrosis in a paracrine
124 hosphorylate Y88 or Y88 and Y74, respectively, thereby promoting intra-assembly phosphorylation (of p
125 elevated levels of EGFR protein and signaling, thereby promoting ISC self-renewal.
126 , protects Mcl-1 from proteasomal degradation, thereby promoting its antiapoptotic activity.
127 membrane and simultaneously binds plasminogen, thereby promoting its conversion to plasmin to destroy
128 ting dimerization of the oncoprotein survivin, thereby promoting its degradation along with spontaneo
129 t sugar moieties on ADAMTS13 interact with MR, thereby promoting its endocytosis by APCs.
130 ibitory effect on FoxM1b by SUMO modification, thereby promoting its nuclear translocation and preven
131 nt an ideal niche in which Salmonella resides, thereby promoting its persistence and dissemination.
132 se the translation of the MDA-7/IL-24 protein, thereby promoting its subsequent toxic effects in panc
133 reased activity of the STAT3 and ERK pathways, thereby promoting keratinocyte growth.
134 f mitotic centromere-associated kinesin (MCAK), thereby promoting leading-edge MT growth and cell pol
135 hield FLT3-ITD from external cytokine control, thereby promoting leukemogenesis.
136 gingival endothelial cell expression of Del-1, thereby promoting LFA-1-dependent recruitment of neutr
137 nd restrain its activation by diverse stimuli, thereby promoting lipogenesis, cholesterol synthesis,
138 n primary tumors and in draining sentinel LNs, thereby promoting LN metastasis.
139 n and pathogenicity of herpes simplex virus 1, thereby promoting long-term infection.
140 feedback that increases type IV pili activity, thereby promoting long-term surface attachment that ca
141 ted because of decreased sirtuin-2 expression, thereby promoting loss of PCK1.
142 molecule 1 (VCAM-1)(+) metastatic tumor cells, thereby promoting lymph node metastasis.
143  tumor-associated lymphatic and blood vessels, thereby promoting lymphatic and hematogenous metastasi
144 stabilize the structure of the mutant protein, thereby promoting lysosomal delivery over retrograde d
145 D ligands MICA and ULBP2 by enhanced shedding, thereby promoting malignant character.
146 nAChR/JAK2/STAT3 downstream signaling cascade, thereby promoting metastasis of PC.
147 loid-derived suppressor cells and macrophages, thereby promoting metastatic tumor growth.
148 ls, and which impairs immune cell homeostasis, thereby promoting MIA-CID development.
149  Th17 lymphocytes induce lung cancer cell EMT, thereby promoting migration and metastatic spreading a
150 e (2-nt 3' overhang) through mono-uridylation, thereby promoting miRNA biogenesis.
151 reduced ubiquitination of mitofusin via HUWE1, thereby promoting mitochondrial fusion and function.
152 incorrect kinetochore-microtubule attachments, thereby promoting mitotic fidelity.
153 ion of the p55alpha/p50alpha subunits of PI3K, thereby promoting more efficient PI3K signaling during
154 mulate epithelial-mesenchymal transition (EMT), thereby promoting motility and in vitro metastasis of
155 alytic subunit to the ING5 and hEaf6 subunits, thereby promoting MOZ HAT activity.
156 d Pontin/Reptin in an energy-dependent manner, thereby promoting mTORC1 activity by facilitating mTOR
157 ity of ubiquitin-specific peptidase 48 (USP48), thereby promoting Na(+)-H(+) exchanger (NHE)-3 degrad
158 ases feeding and increases energy expenditure, thereby promoting negative energy balance.
159 ucible factor-1 alpha (HIF-1alpha) activation, thereby promoting neovascularization and enhancing reg
160 ing opposes BMP signaling during gastrulation, thereby promoting neural induction and the development
161  increases beta-catenin levels in the nucleus, thereby promoting neural progenitor proliferation.
162 te elevated Notch signaling due to trisomy 21, thereby promoting neural stem cell cycling that delays
163 ween pericytes and NSCs was induced by CORM-3, thereby promoting neurogenesis.
164 either miRNA alone, strongly suppressed Rap2a, thereby promoting neuronal differentiation of neural s
165 o potentiate the action of CXCL5 (ENA-78/ LIX), thereby, promoting neutrophil migration into the peri
166 and its RNF4-VCP mediated clearance from DSBs, thereby promoting NHEJ.
167 l lines from autologous or allogeneic sources, thereby promoting NK cytotoxic activity against target
168 ulating the bioavailability of growth factors, thereby promoting normal crosstalk between podocytes a
169 at HG negatively regulates sestrin 2 and AMPK, thereby promoting Nox4-mediated eNOS dysfunction and i
170 opeia virus NP to Z and the budding apparatus, thereby promoting NP incorporation into virions.
171 the trafficking of viral cores to the nucleus, thereby promoting nuclear entry of the viral genome an
172  effects on endocrine and metabolic functions, thereby promoting obesity and associated metabolic dis
173 e fatty acid release from visceral adipocytes, thereby promoting obesity-induced hepatic insulin resi
174 ease their ability to migrate into the uterus, thereby promoting one of the earliest and most importa
175 c cells promote both slow and fast myogenesis, thereby promoting overall maturation of muscle fiber t
176 cellular calcium and oncogenic Kras signaling, thereby promoting pancreatitis and progression to PDA.
177 uit host machinery to sites of virus assembly, thereby promoting particle release from the infected c
178 abrogates the interaction of PD-L1 with CMTM6, thereby promoting PD-L1 degradation.
179 mulating IL-1beta-mediated NF-kappaB activity, thereby promoting peritoneal metastasis of ovarian can
180 at this complex antagonizes the Rrm3 helicase, thereby promoting PFA, by preserving the integrity of
181 rs via fast, repetitive synaptic transmission, thereby promoting phase locking between the presynapti
182  multivalent interactions between nucleosomes, thereby promoting phase separation.
183 gulating phosphatase and tensin homolog (PTEN), thereby promoting phosphorylation of Akt, which leads
184  miR-155 specifically reduced levels of SHIP1, thereby promoting PI3K/Akt activation.
185 on-fragmentation chain transfer (RAFT) system, thereby promoting polymerization of various monomers f
186     GLP-1 and liraglutide activate the GLP-1R, thereby promoting pre-adipocyte proliferation and inhi
187 on of epithelial PAGE4 modulates AR signaling, thereby promoting progression to advanced lethal PCa a
188                 Myofibroblasts drive fibrosis, thereby promoting progressive tissue damage and leadin
189 onset of chaperone-mediated Rpt ring assembly, thereby promoting proper proteasome holoenzyme formati
190 egulated kinase 1/2-dependent mTOR inhibition, thereby promoting pSTAT1 nuclear translocation.
191  in observational studies and clinical trials, thereby promoting public health efforts related to iod
192 differentiation until they reach high density, thereby promoting radial sorting.
193 nuclease activity on the 3'-terminated strand, thereby promoting recombination.
194 IMA kinase Fin1 blocked PP1(Dis2) recruitment, thereby promoting recruitment of Polo to Cut12 and the
195  ensure that sperm move when and where needed, thereby promoting reproductive success.
196 reduces Ca(2+) influx that triggers apoptosis, thereby promoting resilience of the vascular wall duri
197 ly active transcription factors in CRPC cells, thereby promoting resistance to AR-targeted therapies.
198 ive stress and improve mitochondrial function, thereby promoting RGC survival.
199 e that NOD1 detects PG within early endosomes, thereby promoting RIP2-dependent autophagy and inflamm
200 itment of MSK1 and Cdk9 to the cox-2 promoter, thereby promoting RNA polymerase II phosphorylation.
201 trinsic mechanisms regulate cellular behavior, thereby promoting robustness of population dynamics.
202 stabilizes p130, a pRb-related pocket protein, thereby promoting S-phase reentry in postmitotic, diff
203 ducer and activator of transcription 3 (STAT3), thereby promoting self-renewal and tumor progression
204 nition and elicit repulsion between processes, thereby promoting self-avoidance.
205 decreased Hes1 and increased Neurog2 activity, thereby promoting sensory neuron differentiation.
206  (stiff) and decorated (compliant) boundaries, thereby promoting severing.
207 ithin a narrow window of ligand concentration, thereby promoting signaling control.
208 mplex is in kinetic competition with splicing, thereby promoting siRNA production from transposon tra
209 orchestrate higher-order chromosome structure, thereby promoting sister chromatid cohesion, chromosom
210 and boosts the frequency of action potentials, thereby promoting sleep.
211 bly factor to localize at the spindle midzone, thereby promoting spindle midzone dissolution.
212  allergy and affects the epigenome of T cells, thereby promoting stable Treg differentiation and func
213 s beta-amylases at the starch granule surface, thereby promoting starch degradation.
214 helps to reduce flaw sensitivity in the glass, thereby promoting structural reliability.
215 larization and osmotic swelling in precursors, thereby promoting surface expression of the epidermal
216 mulates the translation of G4 harboring mRNAs, thereby promoting survival of leukemic cells.
217 s with FoxO1 in the nucleus of cardiomyocytes, thereby promoting survival.
218 hemokines and produce reactive oxygen species, thereby promoting T cell activation.
219 nt induction of CXCR4 cell surface expression, thereby promoting T cell migration in response to CXCL
220 on and the antigen-presenting capacity of DCs, thereby promoting T cell responses.
221 D4(+) T cells could be controlled by TGF-beta, thereby promoting T(H)17 polarization.
222 enitor cells from IL-2-delivered mTOR signals, thereby promoting Tfh differentiation during acute vir
223 lation of cluster of differentiation 36 (CD36), thereby promoting the formation of inflammatory foam
224  of Nek1 leads to underphosphorylation of TAZ, thereby promoting the abnormal accumulation of PC2.
225 ation of TMPs responding to weak TCR agonists, thereby promoting the accumulation of high-affinity T
226 cobalt ions in desymmetrized "entatic" states, thereby promoting the activation of B(12) -cofactors f
227 ulsion between PV cells and pyramidal neurons, thereby promoting the assembly of perisomatic inhibiti
228 uced phosphorylation of p38, JNK1/2, and BCL2, thereby promoting the autophagic flux.
229  of this cation disfavors meta-C-H borylation, thereby promoting the challenging para-selective react
230 rRNA) and the synthesis of ribosomal proteins, thereby promoting the complex process of ribosome biog
231 asure to prevent the execution of necroptosis, thereby promoting the continued survival of infected m
232 phorylation of p27(KIP1) specifically at T157, thereby promoting the cytosolic mislocalization of p27
233 eposit drug patches at the surface of tissues, thereby promoting the delivery of drugs into target ti
234 ulates the HIF-1alpha pathway in chondrocytes, thereby promoting the demise of these cells.
235 lecules associated with live biological hosts, thereby promoting the development of mitochondria-targ
236 ivate host prothrombin and form fibrin cables, thereby promoting the establishment of infectious lesi
237 y protect a subpopulation of cells from death, thereby promoting the establishment of persistent infe
238 t post-TLI/ATG by increasing HSC cell cycling, thereby promoting the exit of host HSC from the marrow
239 irradiation recovery for efficient DSB repair, thereby promoting the extraordinary radioresistance of
240 esterol in chemokine receptor oligomerization, thereby promoting the formation of a signaling hub ena
241 eracts with tubulin in a GTP-dependent manner, thereby promoting the formation of microtubules.
242 is in turn increases sympathetic input to WAT, thereby promoting the formation of rBAT within white f
243    These interactions in turn stabilize TMH 2, thereby promoting the inhibited conformation of DtpA.
244 tant increase in oxidized nitric oxide levels, thereby promoting the inhibition of PTEN by S-nitrosyl
245 nd spCSF-1 increases with advancing nephritis, thereby promoting the intrarenal recruitment of monocy
246 rotein 1 (TPPP1) mRNA and downregulates TPPP1, thereby promoting the invasion and migration of EBV-re
247 s pre-organized to bind the first Rev monomer, thereby promoting the overall Rev-RRE assembly process
248  prevents the binding of USP9x deubiquitinase, thereby promoting the proteasomal degradation of FOXO3
249 r signals of cortical and subcortical origins, thereby promoting the recruitment of appropriate movem
250 hosphorylating a PP1-docking site in PP2A-B56, thereby promoting the recruitment of PP1.
251  structural component of the nuclear envelope, thereby promoting the release of DNA in the cytosol.
252 ls, which attracts macrophages into the tumor, thereby promoting the resistance to gemcitabine treatm
253 observed in the structure of the closed state, thereby promoting the resulting conformational switch
254  the tubuloglomerular feedback (TGF) response, thereby promoting the rise in GFR.
255 ome assembly leads to activation of caspase 1, thereby promoting the secretion of bioactive interleuk
256 3 nucleotide cleft and the hydrophobic groove, thereby promoting the short-pitch conformation.
257 ss the proliferation of lower-affinity clones, thereby promoting the specificity of the response.
258 s involved in DNA damage signaling and repair, thereby promoting the stability of these transcripts/p
259 nase-1 (PFK1) and inhibits aerobic glycolysis, thereby promoting the utilization of glucose to suppor
260 nd localization within the reproductive tract, thereby promoting their access to oocytes.
261  transport espin-1 to the tips of stereocilia, thereby promoting their elongation.
262 GULATED 15A (COR15A) with GCC or DRE elements, thereby promoting their expression.
263  invadopodium function in breast cancer cells, thereby promoting their invasiveness.
264 ses (E3s), many E2s can also autoubiquitinate, thereby promoting their own proteasomal turnover.
265  and contributes to mitochondrial dysfunction, thereby promoting therapeutic resistance and prostate
266  receptor expression and upregulate autophagy, thereby promoting therapy resistance in breast cancer
267 ruiting Dachs to the apical junctional region, thereby promoting tissue growth.
268 unctions as an inhibitory molecule on T cells, thereby promoting tissue tolerance by limiting long-te
269 e AIP4 with respect to ESCRT-0 ubiquitination, thereby promoting trafficking of CXCR4.
270 er that is dependent on its helicase activity, thereby promoting transcription of its target genes.
271  the ability to traverse the first nucleosome, thereby promoting transcription of most genes.
272 alpha, and its downstream effector kinase MK2, thereby promoting transcription, mRNA stabilization, a
273 which turns eIF5 into translational inhibitor, thereby promoting translation of GCN4, the yeast ATF4
274 tophagy as a cytoprotective adaptive response, thereby promoting treatment resistance.
275 h pulls the alpha1-helix out of the interface, thereby promoting trimerization.
276  breaks the interaction between ShcD and Grb2, thereby promoting TrkB-Grb2 association.
277 diates non-degradative ubiquitination of TSC1, thereby promoting TSC1-TSC2 dimerization and TSC2 stab
278 provide a metabolic advantage to cancer cells, thereby promoting tumor cell proliferation, tumorigene
279 f keratinocytes harboring oncogenic mutations, thereby promoting tumor development.
280 s that activate pattern recognition receptors, thereby promoting tumor growth and metastasis.
281  angiogenesis and lymphangiogenesis in cancer, thereby promoting tumor growth and spread.
282 tivation alters the tumor inflammatory milieu, thereby promoting tumor growth.
283 at NRP-1 activates the tumor microenvironment, thereby promoting tumor growth.
284  chemotherapeutic and immunotherapeutic drugs, thereby promoting tumor growth.
285 rosis factor alpha/nuclear factor kappaB axis, thereby promoting tumor malignancy and subsequent rela
286 TIMP-3 loss might induce chronic inflammation, thereby promoting tumor malignancy as well as poor sur
287 calized MDSC expansion and immune suppression, thereby promoting tumor progression.
288 that impact both tumor and host cell behavior, thereby promoting tumor progression.
289 broblasts (CAFs) in head and neck cancer (HNC), thereby promoting tumorigenesis via modifying the tum
290 ammatory DCs to produce interleukin-12 (IL-12), thereby promoting type 1 polarized immunity.
291 e Cdk6 promoter and activated Cdk6 expression, thereby promoting uncontrolled cell proliferation.
292 ides an outlet for lateral compressive forces, thereby promoting vertical mechanical buckling, which
293 TNF)-related apoptosis-inducing ligand (TRAIL), thereby promoting viral persistence.
294 ffer the ability to directly cleave viral DNA, thereby promoting viral clearance.
295 ein down-regulates BST2 from the cell surface, thereby promoting viral release.
296 uld keep infected cells in an activated state, thereby promoting viral replication.
297  extracellular bacterial cyclic dinucleotides, thereby promoting virulence.
298 y Wnt signaling in the lungs of infected mice, thereby promoting virus-associated disease.
299 tase and stabilizes the AnxA2-S100A10 complex, thereby promoting VWF release.
300 ltransferase MLL1 to promote H3K4 methylation, thereby promoting Wnt target gene transcription.

 
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