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1 d macrophages induce an interleukin-1 (IL-1)-dependent inflammatory cytokine response by recruited mo
2 ults from cancerous cervical cells, K(Ca)3.1-dependent H33258 uptake was rarely observed in epithelia
4 680I/M680I) FMF knock-in mice exhibited IL-1-dependent increased survival relative to wild-type knock
7 e discovery of the cadherin family of Ca(2+)-dependent cell-cell adhesion proteins, which play essent
10 rocessed into RNA-dependent RNA polymerase 6-dependent small RNAs, resulting in their continued turno
12 constitutively active form of acetylcholine-dependent K(+) current (I(KACh)), called I(KH); this is
13 2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2)
14 cy of APTi with two gene families, the actin-dependent motor, myosin XI (a,b), and the putative chiti
16 w that Zn(2+) inhibits AMPARs in an activity-dependent manner, opening up this pathway as a means to
18 Within mammalian brain circuits, activity-dependent synaptic adaptations, such as synaptic scaling
19 Conclusion: (225)Ac-L1 demonstrated activity-dependent efficacy with minimal treatment-related organ
21 Despite the growing interest in activity-dependent plasticity, it is still unclear whether synapt
23 y thought to reflect the outcome of activity-dependent forms of synaptic plasticity, yet activity-ind
24 bilise target cell activity through activity-dependent global scaling have been observed only within
25 the question remains as to whether adjuvant-dependent modulation of T(fh) cells enhances HIV-1 vacci
29 urrent respiratory infections, revealing age-dependent variation and suggesting a role for IgG glycos
30 detected lipids, 95% showed significant age-dependent concentration differences clustering into four
34 dogenic processing of APP, combined with age-dependent iron elevation in the tissue, increases pro-ox
36 These responses are nucleated via the AKAP5-dependent clustering of P2Y(11)/ P2Y(11)-like receptors,
37 Likewise, BMP9/10 treatment induced an ALK1-dependent phenotypic switch from synthetic to contractil
44 table complex with Pol II and acts as an ATP-dependent processivity factor that helps Pol II across a
46 ate that both condensin I and II exhibit ATP-dependent motor activity and promote extensive and rever
47 droxylation signals for dioxgen availability-dependent HIF-alpha degradation via the ubiquitin protea
48 carrier and multicarrier mechanisms for axis-dependent conduction polarity and their identifying band
49 h in turn activates a nuclear factor kappa B-dependent metabolic pathway, leading to aerobic glycolys
50 in a TGF-beta receptor/PI3K/protein kinase B-dependent manner, to regulate hepatic acetyl-CoA and cho
51 -4Ralpha regulation of MMC9s is in part BATF-dependent and occurs via modulation of metabolic transcr
52 ional B cells, through B cell receptor (BCR)-dependent positive selection of fetally derived precurso
53 tors at the plasma membrane to modulate BDNF-dependent gene expression and neuronal dendritic growth
57 Here, we report that the Arabidopsis calcium-dependent protein kinase CPK3 is a key regulator of both
58 acellular Ca(2+) through a Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)-mediated mechanism,
60 of the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA), leading to activation of
62 ted B cells)-dependent inflammation, caspase-dependent apoptosis, or necroptosis in response to extra
64 on in the C-repeat/DREB binding factor (CBF)-dependent and CBF-independent cold signaling pathways to
65 reporter mice; it also exploited both CCL17-dependent and unique CCL17-driven inflammatory pain and
67 th specific binding sites promote rapid Cdk8-dependent Notch turnover, and thereby reduce Notch-depen
69 urine model, Alp1 elicits helper T (Th) cell-dependent lung eosinophilia that is initiated by the rap
70 a-light-chain-enhancer of activated B cells)-dependent inflammation, caspase-dependent apoptosis, or
72 capacities, implicating dysregulation of CoA-dependent intermediary metabolism rather than respirator
73 dy [cPRA] class I and/or II >99%, complement-dependent cytotoxicity panel reactive antibody [CDC PRA+
75 s in infected macrophages in a concentration-dependent manner and demonstrated activity against Trypa
76 d reduction was revealed to be concentration-dependent interfacial chemistry that only occurs among c
77 to membranes in a cholesterol concentration-dependent manner and that the binding is facilitated by
78 ental niche is associated with the condition-dependent expression of immune function and stress respo
80 broad terms developmental stage and context-dependent functions of lineage-defining transcription fa
82 sferred thyroid hormones (THs) exert context-dependent effects on offspring survival and physiology b
83 ing CRISPR-Cas9 technology or in a Postn-Cre-dependent manner (Eprs(flox/+); Postn(MCM/+)) strongly r
88 Cip1) /p27(Kip1) ) inhibit cyclin and cyclin-dependent kinase (CDK) complex that promotes fibrosis an
89 , cyclin-specific docking motifs help cyclin-dependent kinases (CDKs) phosphorylate different substra
91 he Arabidopsis (Arabidopsis thaliana) cyclin-dependent kinase G1 (CDKG1) is necessary for recombinati
93 luenced by DP, but also observed apparent DA-dependent priming activity, with the ADDD+DADD fraction
96 demonstrating the importance of demographic-dependent selection in shaping functional phenotypic var
98 s related to top-down, bottom-up and density-dependent regulation of demographic rates in an imperill
99 experiments beyond range boundaries, density-dependent population models built from long-term demogra
103 ings suggest that PIR-1 modulates both Dicer-dependent and Dicer-independent Argonaute pathways and p
105 te, also showed a phthiocerol dimycocerosate-dependent growth compromise upon limitation of the corre
107 f GOLPH3 and its colocalization with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).
108 tion of multilocus region 34 protein (Dom34)-dependent ribosome recycling system, which splits Lso2-c
113 blocker of HCNs-for 24 h resulted in a dose-dependent higher HRV and lower heart rate at 5 days post
114 in the cochlea, rather cisplatin had a dose-dependent impact on cochlear clock rhythms only after tr
115 ve male NSCLC cell lines demonstrated a dose-dependent induction of linc-SPRY3-2/3/4 following irradi
116 er epithelial progenitor cell line in a dose-dependent manner, achieving far higher efficiency and co
117 levels in both dams and offspring in a dose-dependent manner, but did not change TSH levels, weight,
118 ion and restorative division rates in a dose-dependent manner, leading to tumorous overproliferation
122 ministration of (212)Pb-L2 demonstrated dose-dependent inhibition of tumor growth in the PSMA(+) flan
123 rhbeta-gal uptake by the fibroblasts is dose-dependent and saturable and can be competitively inhibit
127 e near absence of mTOR, CDK1 activates eIF4E-dependent translation in MPs through phosphorylation of
128 ere that a Transcriptional Repressor of EIN3-dependent Ethylene-response 1 (TREE1) interacts with EIN
129 tic hypothesis involves impaired endothelium-dependent vasodilation through reactive oxygen species (
130 response in a conductor involves the energy-dependent mean free path of the charge carriers and is a
131 invariant polynomials or sums of environment-dependent atomic contributions, which have recently emer
133 Hypoxia activates hypoxia-inducible factor-dependent signaling, which in turn regulates metabolic r
136 hereas levels of the other incretin, glucose-dependent insulinotropic polypeptide, were not as profou
137 n cob(II)alamin intermediate via glutathione-dependent alkyltransferase or reductive elimination acti
139 derived from human tissue, stimulated HDAC3-dependent proliferation and countered butyrate inhibitio
142 Here we implement robust, scalable history-dependent programs by distributing the computational lab
143 -independent as well as the pubertal hormone-dependent branching of the mammary epithelium and for pr
144 ermined by the tissue niche in a sex-hormone-dependent manner to limit adipose tissue inflammation.
145 Our findings suggest that HSI2- and HSL1-dependent histone methylation plays critical roles in re
147 a from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for glycolipid in the
148 sistance, explaining why short-term, insulin-dependent glucose utilization does not promote insulin r
149 n human aortic SMCs resulted in increased IP-dependent cAMP production and consecutive facilitation o
153 YBX1 inactivation induces apoptosis in JAK2-dependent mouse and primary human cells, causing regress
156 zone under Pi deficiency increased with LAC2-dependent lignification, suggesting a direct relationshi
157 strogen receptor alpha (ERalpha) is a ligand-dependent transcription regulator, containing two transa
158 ramework for therapeutic targeting of ligand-dependent Hh signaling in human cancers with somatic mut
160 tamalin plays a critical role in the ligand-dependent internalization of mGluR1 and mGluR5, members
161 ot fully understood how plants control light-dependent FAS regulation to meet the cellular demand for
164 sical visual cycle works together with light-dependent processes in both the RPE and neural retina to
165 study reveals a previously undiscovered Lyn-dependent exit route of flaviviruses in LC3+ secretory o
166 phosphorylation and is thus exclusively MAT1-dependent by positioning the CDK7 T-loop in its active c
167 ntext (RdRP mice) exhibit constitutive, MDA5-dependent, and quantitatively dramatic upregulation of m
169 lite concentrations and considers metabolite-dependent regulation while still retaining many computat
170 e show that Agd3 deacetylates GAG in a metal-dependent manner, and is the founding member of carbohyd
172 n of IL1beta in vivo was driven by microbial-dependent activation of toll-like receptor 4 (TLR4) sign
173 findings establish a key role for microbiome-dependent circadian GLP-1 secretion in the maintenance o
174 ine N-oxide (TMAO), an intestinal microbiome-dependent metabolite, worsens graft-versus-host disease
176 t mice compromises suppression of microbiota-dependent activation of CD8(+) T cells, resulting in col
178 However, the magnitude of antimicrobial MR1-dependent activation remained as potent and polyfunction
183 ite for the stable immobilisation of an NADH-dependent dehydrogenase (i.e. lactate dehydrogenase), vi
185 n, (5) S-nitrosothiols did not promote NADPH-dependent reduction of tetra-nitro-blue tetrazolium (TNB
187 of its targets, and show how numerous NEDD8-dependent interprotein interactions and conformational c
188 as astrocytes, which exhibit norepinephrine-dependent Ca(2+) elevations during vigilance, are not we
189 ent Notch turnover, and thereby reduce Notch-dependent transcription at other loci and sensitize tiss
190 debenone combination treatment promoted NQO1-dependent Complex I bypass activity in these cells.
192 nzymes (PHDs) are Fe(II)- and 2-oxoglutarate-dependent oxygenases that act as hypoxia-sensing compone
193 s FBXL5 binding to IRP2 to effect its oxygen-dependent degradation, unveiling a novel and previously
194 CoxFluor enabled the detection of oxygen-dependent changes in COX-2 activity that are independent
195 ring fractionated radiotherapy, using oxygen-dependent quenching of phosphorescence, oxygen probe Oxy
196 would raise the hope for a cure to many P2X7-dependent pathologies, including inflammatory, neurologi
197 tric cancers that are sensitive to other p53-dependent cytotoxic drugs, also display increased sensit
198 ailable, the limited overlap of reported p63-dependent genes has made it difficult to decipher the p6
199 eveal the dynamics and specificity of Parkin-dependent ubiquitylation under endogenous expression con
201 f atelectasis, and 2) ventilate in a patient-dependent manner that minimizes the number of lung units
209 we show that this system exhibits physiology-dependent temperate dynamics at environmentally relevant
212 drenergic stimulation of BAT activates a PKA-dependent mitochondrial Ca(2+) extrusion via the mitocho
213 tion of EP2 receptors and the subsequent PKA-dependent phosphorylation of alpha3GlyRs within the intr
214 conclusion, our results reveal distinct PKC-dependent regulation of CF transdifferentiation and prol
217 at PKA-mediated phosphorylation and PP1/PP2A-dependent dephosphorylation of the alpha2 subunit play a
218 reporting protein-protein interaction (PPI)-dependent, mutation-specific, and drug-driven changes of
219 that EWSR1 is essential for promoting PRDM9-dependent histone methylation and normal meiotic progres
220 xhibited a significant reduction of pristane-dependent induction of splenocyte number and weight.
222 ctly address this question for NMDA receptor-dependent long-term depression (LTD) in the hippocampus.
225 Together our data show that DNA-PK has RNA-dependent, cNHEJ-independent functions during ribosome b
226 AD(+) capping are instead processed into RNA-dependent RNA polymerase 6-dependent small RNAs, resulti
227 ransgenic mice expressing a picornavirus RNA-dependent RNA polymerase (RdRP) outside the viral contex
229 ions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular fr
233 c42EP5 affects these functions through SEPT9-dependent F-actin cross-linking, which enables the gener
236 lular detachment, which is followed by SIRT3-dependent increases in SOD2 mRNA during sustained anchor
239 of the gut microbiome that elicit a Smarcad1-dependent colitis response, including members of the poo
240 a membrane and promotes activation of an SRC-dependent signaling cascade that controls YAP nuclear sh
241 vented EphB1 binding to Cav-1 as well as Src-dependent Cav-1 phosphorylation, indicating the importan
242 ndicate that it is required for Pnr- and Srp-dependent gene expression, suggesting general GATA cofac
243 of GABA and insulin signaling in starvation-dependent modulation of olfactory sensory neuron (OSN) f
244 (AKT) inhibitor MK2206 blocks the starvation-dependent increase in lysosomal V-ATPase activity withou
245 MS3-6 expression strongly inhibits STAT3-dependent transcriptional activation and disrupts STAT3
248 Robust literature has examined social status-dependent brain gene expression profiles across vertebra
250 -type (WT), but not FX synapses, by stimulus-dependent ATP synthase beta subunit translation; this in
252 release and thus activates the TMEM173/STING-dependent DNA sensor pathway, which results in macrophag
255 xible decision-making functions in substance-dependent individuals are a consequence of drug-induced
256 with experiments that probe proteins in a T-dependent fashion, e.g., for assessing the stability of
257 ile conjugation of long-chain Vi generates T-dependent antigens, the conjugates also retain T-indepen
258 e temperature range, paving the way toward T-dependent high-throughput screening applications by HDX-
261 ute a major role to post-melting temperature-dependent diffusion of hydrogen occurring above the melt
262 ese results identify a plausible temperature-dependent molecular mechanism, which contributes to the
263 ELISA)-based assay that uses the temperature-dependent loss of conformational epitopes to measure the
264 -dynamics simulations reveal the temperature-dependent morphological changes in poplar wood biomass d
266 C-NAc neurons and corresponding testosterone-dependent male resilience to reduced sucrose preference
270 subtypes in the mPFC produced dose and time-dependent antidepressant effects in the forced swim and
273 a time dependent variable by generating time-dependent Cox models; HRs at an ELF threshold of 10.51 w
276 ings, an alternative method of modeling time-dependent inhibition that simplifies assay setup and all
277 t-operative survival was assessed using time-dependent Cox proportional hazard regression analysis an
278 h current criteria increased the 5-year time-dependent area under the curve from 0.68 to 0.81 (P=0.00
279 ermined the role of GSK3beta in spike timing-dependent long-term potentiation (tLTP) in the chronic u
280 hat EPEC induces pyroptosis in IECs in a Tir-dependent but actin polymerisation-independent manner, w
281 sists in muscle, and we asked if this tissue-dependent persistence was linked to MHC expression.
282 interactions, which explains the topography-dependent diversity in fibroblast phenotypes observed he
283 even in the solid state and exhibit topology-dependent pai transmission and exciton migration; these
287 that viperin appears to facilitate ubiquitin-dependent proteasomal degradation of some of the protein
290 esters and siloxanes suggest that volatility-dependent partitioning processes modulate airborne SVOC
291 r in external Ba(2+) than in Ca(2+); voltage-dependent kinetics of activation, inactivation, and deac
293 terminants of S4 helix motion during voltage-dependent transition from the intermediate to the activa
294 Two candidate modules featuring voltage-dependent Ca2+-channels link these outputs to the downst
297 he stiffness gradient corresponds to a Wnt5a-dependent domain of fibronectin expression, raising the
298 study demonstrates that proximal tubule YAP-dependent paracrine mechanisms play an important role in