ライフサイエンスコーパス: -mediated activation

1 tumor growth, but was essential for dectin-1-mediated activation of macrophages and natural killer (N

2 Thus, HIF-1-mediated activation of 5-HT signalling promotes axon reg

3 nhibitor substantially inhibits LFA-1/ICAM-1-mediated activation of Notch signaling.

4 skeleton contributes to IRS-2- but not IRS-1-mediated activation of AKT by IGF-1.

5 In this study, we investigated the MCP-1-mediated activation of Pyk2 (particularly by the phospho

6 onfirmed PTH1R-mediated inhibition and Mkl-1-mediated activation of Col3a1 transcription.

7 tion in platelets markedly decreases talin-1-mediated activation of platelet beta1- and beta3-integri

8 L-1R) expression, are refractory to IL-1beta-mediated activation in vitro and in vivo, and fail to re

9 ition, and PKCdelta was required for PIP(2) -mediated activation of TRPC1 currents.

10 annel expression, but not changes in Ca(2+) -mediated activation of SK channels, contributes to exace

11 icus (SE), driven partly by cyclooxygenase-2-mediated activation of prostaglandin EP2 receptors.

12 Notably, 4-CPPC inhibited MIF-2-mediated activation of CD74 and reduced CD74-dependent s

13 irst time that IL10 suppresses Smad-miRNA-21-mediated activation of BM-FPCs and thus modulates cardia

14 The 25HC-mediated activation of acyl-CoA:cholesterol acyltransfer

15 to better understand the impact of caspase-3-mediated activation of kinase activity.

16 -13 production strongly depends on the MK2/3-mediated activation of ERK1/2 and PI3K signaling.

17 transducer and activator of transcription 3-mediated activation of the focal adhesion kinase and its

18 itinase, DUB3, as a target of CDK4/6; CDK4/6-mediated activation of DUB3 is essential to deubiquitina

19 One involves cAMP/protein kinase A-mediated activation of the Src homology region 2 domain-

20 that telomere dysfunction drives pATM/c-ABL-mediated activation of the YAP1 transcription factor, up

21 BP1- is strictly dependent on the amino-acid-mediated activation of RagC and RagD GTPases, but is ins

22 nt tropomyosin cofilaments affects the actin-mediated activation of NM-2B and the release of the ATP

23 tress through a mechanism that requires 2-AG-mediated activation of CB(2) receptors, whose transcript

24 efine the minimal sequence required for AggR-mediated activation and show that the correct positionin

25 e these activities, we monitored KOR agonist-mediated activation of ROS in transfected live cells by

26 We found that agonist-mediated activation of prostaglandin F receptors and pro

27 enesis and gene rescue studies show that Akt-mediated activation of PRAS40 via threonine 246 phosphor

28 However, TNF-alpha-mediated activation of TonEBP did not cause induction of

29 Specifically, alpha6beta4-mediated activation of Src and STAT3 suppresses expressi

30 gment IgA production by integrin alphavbeta8-mediated activation of transforming growth factor-beta (

31 AMPK-mediated activation of mTORC2 did not result from AMPK-m

32 PARK2 depletion contributes to AMPK-mediated activation of endothelial nitric oxide synthase

33 ore, we discuss the control of anaphylatoxin-mediated activation of dendritic cells and allergic effe

34 idine-initiated and p-toluenesulfinate anion-mediated activation of the allenyl sulfone analogous to

35 y titres, NK cell-mediated ADCC and antibody-mediated activation of MIP-1beta in NK cells as the four

36 ally, we were interested in whether antibody-mediated activation through the classical pathway was a

37 stimulatory signal to T cells during antigen-mediated activation.

38 s crucial to beta-2-adrenoceptor (beta(2)AR)-mediated activation of cystic fibrosis transmembrane con

39 tochondrial biogenesis, contributing to aROS-mediated activation of the DDR and cell cycle arrest.

40 as a potent repressor of both XBP1s and ATF6-mediated activation.

41 est with protein aggregate clearance by Atg8-mediated activation of the Nrf2-like transcription facto

42 odulator protein, implicating a role for ATM-mediated activation of canonical NF-kappaB transcription

43 However, prolonged ATP-mediated activation of P2X(7) leads to formation of a po

44 The rapid, ATP-mediated activation of P2X(7) induces a fast-inward cati

45 ATR-mediated activation of DUX requires GRSF1-dependent post

46 in vivo metastatic melanoma model, ephrin-B2-mediated activation of EphB4 induces tumor cell repulsio

47 signal-regulated kinase signalling after BCR-mediated activation compared with healthy controls.

48 ne deacetylase 6 (HDAC6) modulates TGF-beta1-mediated activation of the Notch pathway.

49 ist based on its ability to block (i) BigLEN-mediated activation of GPR171 in heterologous cells, (ii

50 hypothesized that mithramycin inhibited bile-mediated activation of the farnesoid X receptor (FXR).

51 ered action potentials in FSIs preceding BLA-mediated activation of MSNs.

52 sed GM2-synthase transcription, and butyrate-mediated activation of GM2-synthase mRNA expression in S

53 ively, our findings demonstrate that calcium-mediated activation of the calcineurin pathway acts as a

54 es AMPK after energy stress, whereas calcium-mediated activation of AMPK requires CaMKK2, although th

55 CALR C terminus is required for mutant CALR-mediated activation of JAK-STAT signaling.

56 evels in Or47b ORNs, likely leading to CaMKI-mediated activation of the histone-acetyl transferase CB

57 emoval of ATP primes the holoenzyme for cAMP-mediated activation.

58 s widely accepted to be associated with cAMP-mediated activation of protein kinase A (PKA).

59 ich to study the mechanisms regulating CASP8-mediated activation of cell death and inflammatory signa

60 alidate the model by inhibiting beta-catenin-mediated activation of DPAGT1 expression and predicting

61 ng protein DDB2 is critical for beta-catenin-mediated activation of RNF43, which restricts Wnt signal

62 pose that the postnatal ethanol-induced CB1R-mediated activation of CDK5 suppresses Arc and Rac1 expr

63 This CB1R-mediated activation of CDK5 signaling during active syna

64 menin via cholecystokinin B receptor (CCKBR)-mediated activation of PKA.

65 blood monocytes, and that CD300c and CD300e-mediated activation was quantitatively different in neon

66 lo-like kinase (Plk) control Cdc20- and Cdh1-mediated activation of the APC/C.

67 ranodal T cell migration, and dendritic cell-mediated activation of antiviral CD8+ T cells.

68 tosis was initiated by multiple myeloma cell-mediated activation of Notch signaling and was further a

69 gene expression patterns indicative of cell-mediated activation and NK cytotoxicity.

70 suggests that UAG is subject to target cell-mediated activation - a novel mechanism for manipulating

71 ischemia and that fenofibrate rescues CEPT1-mediated activation of PPARalpha.

72 We also show that CLEC5A-mediated activation of macrophages enhanced cytokine ela

73 Cobalt-mediated activation of peroxymonosulfate (PMS) has been

74 t BIVV009 significantly inhibited complement-mediated activation and proliferation of primary human B

75 hypothesized that stress, via corticosteroid-mediated activation of the glucocorticoid receptor (GR),

76 opy of a haploinsufficient gene using CRISPR-mediated activation (CRISPRa) in Sim1 and Mc4r heterozyg

77 revealed that mutation D22A accelerated CTSB-mediated activation by 2-fold.

78 Interestingly, CTSB-mediated activation of the K24G mutant became more sensi

79 Experimental separation of CTSB-mediated activation from autoactivation in mice is possi

80 grin-linked kinase to be essential for CXCL1-mediated activation of NLRP3 inflammasome.

81 rpesvirus 68 are defective in BCR- and CXCR4-mediated activation of the PI3K pathway, and this, we sh

82 on between STAM1 and beta-arr1 reduces CXCR4-mediated activation of FAK and chemotaxis.

83 versus activated macrophages where cytokine-mediated activation renders Mtb tolerant to four frontli

84 ansmission at direct pathway synapses and D1-mediated activation of motor activity.

85 Altogether, we present a DAG-mediated activation mechanism for TRPC4/5 channels tight

86 stance involves diacylglycerol-mediated (DAG-mediated) activation of protein kinase C-epsilon (PKCeps

87 DNA damage-mediated activation of extracellular signal-regulated ki

88 sed the impact of HFD on dendritic cell (DC)-mediated activation of T cells.

89 dipogenesis in vivo and demonstrate that DEX-mediated activation of GR accelerates, but is dispensabl

90 RDA2 is required for DFPM-mediated activation of immune signaling, including phosp

91 Diabetes-mediated activation of cardiomyocyte FOXO1 increases KLF

92 Importantly, Dip1-mediated activation of Arp2/3 complex creates linear fil

93 Cytosolic DNA-mediated activation of the transcription factor IRF3 is

94 d IFN-alpha production in pDC requires DOCK2-mediated activation of Rac1 leading to activation of IKK

95 neurons, and (iii) feeding induced by DREADD-mediated activation of BigLEN containing AgRP neurons in

96 athoinhibition elicited by selective, DREADD-mediated activation of ArcN NPY/AgRP neurons.

97 In vivo, DREADD-mediated activation of GABAergic NTS neurons increased s

98 Drug-mediated activation of adipocyte G(i) signaling may prov

99 ecretion, which depended critically on DUOX1-mediated activation of epithelial epidermal growth facto

100 Thus, DUX4-mediated activation of Ret prevents myogenic differentia

101 ies directly a host factor involved in EBNA3-mediated activation and provides a new insight into how

102 First, EGF-mediated activation of EGFR blunted fusion kinase inhibi

103 &2 kinase activities reveals concomitant EGF-mediated activations of both kinases in HeLa cells.

104 Raft targeting of p110alpha allowed its EGFR-mediated activation by GPCRs.

105 ing complex allowed IL-33 to induce the EGFR-mediated activation of the MAP-kinase signaling pathway

106 tivated kinase alpha, abrogated endorepellin-mediated activation and co-localization of Beclin 1 and

107 our knowledge, a novel mechanism of eotaxin-mediated activation of TrkA and its role in regulating e

108 ing assay that is capable of monitoring EPAC-mediated activation of cellular Rap1 in an isoform-speci

109 Epigenetic-mediated activation of non-canonical WNT/beta-catenin/MM

110 ERbeta represses ERalpha-mediated activation of the ERE and the RET promoter cont

111 EREG-mediated activation of EGFR enhanced nociception through

112 t expression of DUSP2 inhibits ERK3 and ERK4-mediated activation of its downstream substrate MK5.

113 entified the SRC kinase contributing to ETV2-mediated activation of the hemangiogenic program.

114 fecting thousands of genes that we call exon-mediated activation of transcription starts (EMATS), in

115 phosphorylation of c-Src and subsequent FAK-mediated activation of ERK and AKT signaling pathways.

116 ce of IL-6 were also more susceptible to Fas-mediated activation-induced cell death in vitro.

117 cell differentiation status in promoting Fc-mediated activation of NK cells after vaccination, raisi

118 tions including development, IgE:FcepsilonRI-mediated activation, and responses to food allergen.

119 f mast cell function on repeated FcepsilonRI-mediated activation.

120 is produced after antigen-specific IgE/FceRI-mediated activation signals and functions as an endogeno

121 FGF19-mediated activation of SHP via phosphorylation recruits

122 Obviously, avoidance of flagella-mediated activation of host immunity is advantageous for

123 These sequences provide EWS/FLI-mediated activation to reporter constructs, suggesting t

124 gration are regulated through the Arl4C-FLNa-mediated activation of Cdc42.

125 to the granules and lipid bodies during fMLP-mediated activation.

126 se results highlight the importance of c-Fos-mediated activation of lipid synthesis for proper nervou

127 duced ATP release and subsequent P2Y2/Gq/G11-mediated activation of downstream signaling that results

128 ric human beta(3) GABA(A)R that enables GABA-mediated activation.

129 GABA(A)R are sufficient to reconstitute GABA-mediated activation and suggests that Tyr(87) prevents i

130 hat promote mitophagy reversed LPS/IFN-gamma-mediated activation of macrophages and led to immunopara

131 these two residues were essential for GAPDH-mediated activation of TNF receptor-associated factor 2

132 revealed that PKD1 is indispensable for GBS-mediated activation of MAPKs and NF-kappaB and subsequen

133 pbp2(-/-) mice (Ishimura et al., 2016), GCN2-mediated activation of the integrated stress response (I

134 res guanine nucleotide exchange factor (GEF)-mediated activation of downstream Ras family small GTPas

135 -gHgL neutralizing antibodies can block gHgL-mediated activation of gB through different surface epit

136 uring development, measure ambient glutamate-mediated activation of developing cortical interneurons,

137 ing nerve injury in mice, perhaps via a GPCR-mediated activation mechanism, and suggest that inhibiti

138 Moreover, GPCR-mediated activation of G(q) signaling also stimulated gl

139 nduced positive GC response element [(+)GRE]-mediated activation of transcription are partially under

140 ne Pgamma contribute to Gt(alpha)*-GTPgammaS-mediated activation of PDE6.

141 cores, which release H2S directly upon H2O2-mediated activation.

142 iated suppression of StBMI1-1/3, and H3K4me3-mediated activation of miR156 in StMSI1-OE plants.

143 (HCMV) and that THY-1 is important for HCMV-mediated activation of phosphatidylinositol 3-kinase (PI

144 We then studied the mechanism of HDAC1-mediated activation.

145 suggesting a causal relationship between HMR-mediated activation of PIF4 target-genes and PIF4 accumu

146 from this domain competitively inhibits HopQ-mediated activation of the Cag virulence pathway, as gen

147 ocious B-lymphoid differentiation, while Hox-mediated activation of Meis1 suppresses myeloid differen

148 f AhR target genes in M-MO and that the 5-HT-mediated activation of AhR is 5-HT(2B) dependent because

149 ote PABP recruitment and necessary for ICP27-mediated activation.

150 IgE-mediated activation of mast cells is a hallmark of an an

151 was associated with STAT6 signaling and IgE-mediated activation controlled by eosinophils, mast cell

152 ressed the combined effects of IL-33 and IgE-mediated activation on mouse and human mast cells.

153 us inhibitor of IgE loading to FceRI and IgE-mediated activation.

154 tic reactions by essentially eliminating IgE-mediated activation of mast cells.

155 ducing mast cell responses and enhancing IgE-mediated activation.

156 tantially different releasates following IgE-mediated activation.

157 asma cells (PCs), which are required for IgE-mediated activation of mast cells and basophils.

158 viously reported effects of TGF-beta1 on IgE-mediated activation, demonstrate that TGF-beta1 can prov

159 nistically, the omega-3 epoxides promote IgE-mediated activation of mast cells by downregulating Srci

160 estive of a direct link between repeated IgE-mediated activation of mast cells and chronic allergy.

161 tory receptor CD33 profoundly suppressed IgE-mediated activation of mast cells, prevented anaphylaxis

162 on, rendering mast cells unresponsive to IgE-mediated activation.

163 IL6-mediated activation of STAT3 is implicated as a critical

164 MEDI5117 inhibited IL6-mediated activation of STAT3, suppressing the growth of

165 dopamine control, through a concomitant ILC-mediated activation of the pmVTA.

166 gulating ILK enrichment in exosomes, and ILK-mediated activation of NF-kappaB pathway in recipient ce

167 On the other hand, inflammasome-mediated activation drives accumulation of neutrophils,

168 Finally, mTECs regulate both iNKT-mediated activation of thymic dendritic cells, and iNKT

169 ned whether Elmo2 contributes to the insulin-mediated activation of Rac1 and Akt.

170 that alphaE-catenin inhibits beta4 integrin-mediated activation of SRC tyrosine kinase.SRCis the fir

171 of phorbol 12-myristate 13-acetate/ionomycin-mediated activation signals.

172 ined native chemical ligation and isonitrile-mediated activation strategies.

173 n the overexpression of IFN-beta: first, JNK-mediated activation of c-jun, which binds to the IFN-bet

174 ion and replication by suppressing NF-kappaB-mediated activation of viral transcription.

175 pression in EMT cells through p38 MAP kinase-mediated activation of the JunB transcription factor.

176 NO levels, ASS1 expression facilitates KSHV-mediated activation of the STAT3 pathway, which is criti

177 LasR-mediated activation occurs at the distal promoter site,

178 eptor is required for its appropriate ligand-mediated activation by PDGF-AA.

179 ARbeta/delta in cancer is dictated by ligand-mediated activation.

180 eceptors, allowed cross-reactivity of ligand-mediated activation and growth.

181 ed by PPARD that failed to respond to ligand-mediated activation.

182 Light-mediated activation (660 nm) of the Mito-FAP-MG-2I compl

183 nterface without the need for heat- or light-mediated activation.

184 The initial visible light-mediated activation of a variety of monosubstituted or d

185 inhibition of NF-kappaB abolished LINC00305-mediated activation of cytokine expression.

186 BTKB66 potently inhibited lipopolysaccharide-mediated activation of bone marrow-derived neutrophils a

187 LPS-mediated activation of Toll-like receptor 4 (TLR4) in ma

188 demonstrate that prevention of p38beta MAPK-mediated activation of p300 by the FDA-approved kinase i

189 Whereas NLRX1 suppressed MAVS-mediated activation of IRF3, it conversely facilitated v

190 In the absence of LGP2, MDA5-mediated activation of type I IFN signaling was abrogate

191 ast to the well-established transition-metal-mediated activation of white phosphorus (P(4)), the meta

192 These actions depend on metformin-mediated activation of AMP kinase (AMPK).

193 ibition in human THP1 cells enables microRNA-mediated activation.

194 Methods: MMP-mediated activation of PA-L1 was correlated to anthrax r

195 Importantly, the Mn2+-mediated activation positively couples with dsDNA-depend

196 MrgprB2-mediated activation of local mast cells also clears cuta

197 mulation of phosphorylated PRAS40 and mTORC1-mediated activation of HIF1alpha.

198 Finally, we demonstrate that the eMaSC-MVs-mediated activation of the Wnt/beta-catenin signaling pa

199 e-dependent manner, has no role in the Mxr1p-mediated activation of ACS1 expression.

200 vely, our results demonstrate that TLR/MyD88-mediated activation of XBP1 causes skeletal muscle wasti

201 an senescent fibroblasts, DDR precluded MYOD-mediated activation of the myogenic program.

202 ing myoblast determination protein 1 (MYOD1)-mediated activation of myogenic differentiation.

203 ily kinases (SFKs) are involved in both NMDA-mediated activation of TrkB- and TrkB-mediated tyrosine

204 the degradation of ribosomal proteins by p17-mediated activation of E3 ligase MDM2 that targets ribos

205 n cancer cells and subsequently promotes p53-mediated activation of its transcriptional targets such

206 phagy in the development of PDAC through p62-mediated activation of NRF2.

207 effects occur, at least in part, through p63-mediated activation of enhancers at pro-inflammatory cyt

208 ch enables tumor models to evade palbociclib-mediated activation of RB, could be targeted using a cli

209 cretion, (ii) synergistic enhancement of PAR-mediated activation of the small GTPase RAP1, a regulato

210 ing cancer cells via non-canonical paracrine-mediated activation of GLI activity that is dependent on

211 We also explored the mechanism of Pax8-mediated activation of potential target genes in inner m

212 nd provide novel mechanistic insights for PB-mediated activation of hPXR.

213 ory responses by inhibiting phosphoinositide-mediated activation of TAK1.

214 LMP1-transformed cells led to phosphorylase-mediated activation of the PI3K/AKT pathway and inductio

215 e pathway genes and inducing phosphorylation-mediated activation of components of the DNA damage path

216 ation of RhoA in this system depends on PI3K-mediated activation of GEF-H1 and p115 RhoGEF.

217 l signaling network involving mTORC2-PKCzeta-mediated activation of the calcium-dependent phospholipa

218 ockdown of LPCAT3 in mice affected PPARdelta-mediated activation of several hepatic genes involving i

219 tion of their surface abundance and pressure-mediated activation in myocytes and thus control of arte

220 es in our laboratory have shown that Gas6/PS-mediated activation of TAM receptors on tumor cells lead

221 Interestingly, this PTPRF-mediated activation of Wnt signaling was blocked in cell

222 However, the molecular mechanism of PXR-mediated activation of ethanol (EtOH)-induced steatosis

223 lity by reducing GABA(B) receptor (GABA(B)R)-mediated activation of G-protein-coupled, inwardly recti

224 and that Rap1 positively regulates the RasC-mediated activation of TORC2 in Dictyostelium.

225 ssential for the P2X purinoceptor 7 receptor-mediated activation of unconventional protein secretion.

226 Moreover, the mutations ablated receptor-mediated activation of serum response factor luciferase,

227 Adipocyte function is regulated by receptor-mediated activation of heterotrimeric G proteins.

228 oxidation, without affecting T cell receptor-mediated activation.

229 Toll-like receptor- and complement receptor-mediated activation.

230 ting FLIP, a key modulator of death receptor-mediated activation of caspase-8.

231 regulation and initiation of death receptor-mediated activation of programmed cell death is the aspa

232 is process is underpinned by 5-HT1A receptor-mediated activation of G-protein-coupled inwardly rectif

233 iposity and implicated in toll-like receptor-mediated activation of macrophages-key cellular players

234 ng from N-methyl-D-aspartate (NMDA) receptor-mediated activation of nicotinamide adenine dinucleotide

235 nucleotide exchange activity yet no receptor-mediated activation of nucleotide exchange.

236 e technology is suited for studying receptor-mediated activation in cell lines endogenously expressin

237 vely in SKM cells demonstrated that receptor-mediated activation of SKM G(q) signaling greatly promot

238 sis for kinetic proofreading in the receptor-mediated activation of Ras.

239 demonstrated that Norbin promotes the P-Rex1-mediated activation of endogenous Rac1 upon stimulation

240 f the MET coreceptor NRP1 and additional Rho-mediated activation of the actomyosin system.

241 e results indicate that IQGAP1 enhances RhoA-mediated activation of DIAPH1 in vivo Collectively these

242 ting protein-1 (IQGAP1), which enhances RhoA-mediated activation of the Diaphanous-related formin (DI

243 , specific cargoes are internalized by ROCK2-mediated activation of myosin II isoforms to mediate spa

244 st-mediated epithelial apoptosis through ROS-mediated activation of beta-catenin/FOXO1 signaling path

245 enable the autocatalytic, and in general ROS-mediated, activation of (1)O2 sensitization providing a

246 We show that there are two modes of 3'RR-mediated activation of I promoters: coactivation and com

247 of IL-36gamma and highlight that cathepsin S-mediated activation of IL-36gamma may be important in th

248 ted cell death by inhibiting gamma-secretase-mediated activation of Notch signaling.

249 hondrial biogenesis, possibly through SERCA2-mediated activation of AMP-activated protein kinase path

250 The molecular details of ferric siderophore-mediated activation of the iron import machinery through

251 These results indicate that Gq-signaling-mediated activation of forebrain excitatory neurons duri

252 NAMPT/SIRT2-mediated activation of LMO2 by deacetylation appears to

253 Mechanistically, SM-mediated activation of NF-kappaB-inducing kinase (NIK) a

254 MYO6 localization to invasion foci, and SopE-mediated activation of PAK recruited MYO6 to actin-rich

255 We demonstrate reactive oxygen species-mediated activation of AMP-activated kinase in Huh7.5 ce

256 ted the key role of this SRE motif in SREBP2-mediated activation of C-ACSL1 gene transcription.

257 ner, which occurs in addition to the Stachel-mediated activation.

258 ned strong evidence in favor of the HN stalk-mediated activation of paramyxovirus fusion.

259 iggering, a notion consistent with the stalk-mediated activation model of paramyxovirus fusion.

260 w insights into the role of acetylated STAT3-mediated activation of IGF2 transcription in HDI resista

261 CBs promote vascular remodeling through STIM-mediated activation of ORAI.

262 tress in beta-cells by suppressing ER stress-mediated activation of all three branches of unfolded pr

263 DNA replication stress-mediated activation of the ATR kinase pathway is importa

264 Consequently, we hypothesized that stress-mediated activation of the GR can stimulate productive i

265 stimulated insulin secretion by promoting SU-mediated activation of Epac2.

266 t these receptors are required for substrate-mediated activation of the proteasome's unfolding abilit

267 ich can be prevented by topical sulforaphane-mediated activation of NRF2.

268 ownstream TGF-beta signaling identified TAK1-mediated activation of p38 MAPK as the critical pathway

269 ts imply that cell cycle arrest inhibits Tax-mediated activation of sense transcription without affec

270 Consistently, TBL1XR1-mediated activation of Wnt signaling was up-regulated by

271 ells, which depends on T cell receptor (TCR)-mediated activation of beta(2)-integrins.

272 -2, IL-4, and IL-7 responses, as well as TCR-mediated activation and proliferation, of CD4+ T cells.

273 TGFbeta-mediated activation of autophagy has recently been sugge

274 Mechanistically, GRM3 antagonizes TGFbeta-mediated activation of protein kinase A and inhibition o

275 l drug adefovir dipivoxil attenuated TGFbeta-mediated activation of LX-2 or primary rat HSCs in vitro

276 I receptor sensitizing PDAC cells to TGFbeta-mediated activation of p38 and SMAD signals.

277 he contribution of PAR1 and PAR4 to thrombin-mediated activation of the platelet fibrin receptor (GPI

278 Although TLR-mediated activation of MZ B is known to trigger humoral

279 ults define a differential regulation of TLR-mediated activation and differentiation of MZ B cells by

280 lipoylated E2 subunit of PDH to suppress TLR-mediated activation of host macrophages by bacterial lip

281 Here we demonstrate that TLR-mediated activation of CD5+ B-1 cells induced the rapid

282 ic cells (DCs) and plasmacytoid DCs upon TLR-mediated activation and detectable by Nkrp1g, which damp

283 er the rate of IFN-gamma production upon TLR-mediated activation.

284 he lungs can be sustained by persistent TLR4-mediated activation of lung conventional dendritic cells

285 IRAK4 repressed SLE immune complex- and TLR7-mediated activation of human plasmacytoid dendritic cell

286 appears to be of crucial importance for TLR9-mediated activation of Syk.

287 y nuclear translocation of IRF3 whereas TLR9-mediated activation occurs through IRF7.

288 as TAK1, IKKs, and PP2A, that impairs TRAF6-mediated activation of NF-kappaB and expression of pro-i

289 g, a process that was dependent on TLR-TRAF6-mediated activation of A20.

290 binding, and this suggests that upon TRIM25-mediated activation of RIG-I, RIG-I moves away from TRIM

291 Here we reveal that TrkB-mediated activation of Akt protects against hippocampal

292 We subsequently demonstrated that TrkB-mediated activation of phospholipase Cgamma1 is required

293 We previously discovered that TrkB-mediated activation of phospholipase Cgamma1 promotes ep

294 This downregulation, in turn, inhibits TRPA1-mediated activation of FGFR2, hindering the metastatic p

295 cular cells was due to the inhibition of TSH-mediated activation of the mTOR complex 1/ribosomal prot

296 its ability to directly regulate urokinase -mediated activation of plasminogen (Pg).

297 ich was further evidenced by CRISPR/Cas9-VPR-mediated activation of NICI expression.

298 ation but is a specific requirement for WASP-mediated activation.

299 atin landscaping, we show that following WNT-mediated activation of McSCs, BMP and WNT pathways colla

300 Thus, TORC2-dependent and Ypk1-mediated activation of Muk1 provides a control circuit f