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2 ectly classified 456 out of the 457 COVID-19-negative serum samples tested (424 of them collected bef
4 ast cancer cell line (ER-positive and HER(2)-negative) demonstrated specific uptake with a maximum in
8 Study 1 randomly assigned (1:1) HLA-B*5701-negative adults without hepatitis B virus co-infection t
9 nting the number of Ki-67-positive and Ki-67-negative tumor cells within a subjectively picked hot-sp
10 type-1 BrS pattern after ajmaline (ajmaline-negative); (4) 47 normal subjects; (5) 18 patients with
12 neurodegeneration, 19 patients with amyloid-negative neurodegeneration, and 17 healthy controls were
13 d various strains of both Gram-positive and -negative bacteria revealed distinct binding patterns, wh
14 .5) from a discovery cohort of HLA antibody-negative, endothelial cell crossmatch-positive sera obta
16 review, 91.1% of manual-positive/automation-negative specimens were due to expert rules that reporte
17 om the lowest concentrations in amyloid beta-negative young adults and cognitively unimpaired older a
21 colleagues perform a genome-wide CRISPR-Cas9-negative loss-of-function screen and identify WEE1 kinas
22 ucts, we identified a memory-progenitor CD39-negative stem-like phenotype (CD39(-)CD69(-)) associated
23 months vs 19% and 1.6 months for classifier-negative patients (hazard ratio, 0.49; 95% confidence in
24 phthalmitis (2 Candida glabrata, 2 coagulase-negative Staphylococcus, 1 Streptococcus pneumoniae).
25 howed the following sensitivities (coagulase-negative staphylococci not included): Gram-positive bact
26 for the clinical observation that coagulase-negative staphylococci are a highly prominent infectious
27 ), 29 (31.5%), and 13 (14.1%) were coagulase-negative staphylococci, other gram-positive, and gram-ne
29 522 influenza ED visits, N = 274 226 culture-negative pneumonia hospitalizations, and N = 113 997 cul
30 ia hospitalizations, and N = 113 997 culture-negative pneumonia ED visits included in our analyses.
31 Change in clinical management for culture-negative endophthalmitis eyes was based on worsening cli
34 htheriae by culture and Elek, 6 were culture-negative but PCR-positive for diphtheria toxin gene, 1 w
39 ations drive pathogenesis through a dominant-negative loss-of-function mechanism in autophagy and tha
40 t the fusion protein acts through a dominant-negative mechanism to cause this fatal mitochondrial dis
41 of the Spc110 C terminus acts as a dominant-negative mutant that titrates endogenous Spc110 from the
42 n in AML patients (R882H) encodes a dominant-negative protein that reduces methyltransferase activity
43 paB kinase inhibitor BAY11-7085 and dominant-negative mutant IkappaBalphaM inhibited NF-kappaB activi
46 cal neurons using overexpression of dominant-negative forms of several transcription factors, includi
48 ed vesicle traffic similarly to the dominant-negative truncated protein SYP121(DeltaC), which blocks
49 es to differentiate from CD4(-)CD8(-) double-negative (DN) cell to CD4(+)CD8(+) double-positive (DP)
50 identify CD4(-)CD8(-)TCRalphabeta(+), double-negative (DN) T cells, in mouse secondary lymphoid organ
52 r reactivity to autoantigens compared to DSA-negative (P < .0001) and AMR patients with DSA and PRA >
54 w that SOX11 confers distinct features to ER-negative DCIS.com breast cancer cells, leading to popula
62 ed morbidity, fewer false-positive and false-negative results, lower-cost, and higher analytical freq
66 d on high-risk characteristics, and no false-negative tears progressed to detachment at follow-up.
67 been misinterpreted, reviews causes of false-negative and false-positive results, and provides strate
70 on rate (CDR) per 1000 women screened, false-negative rate per 1000 women screened, positive predicti
72 diagnostic test results (ie, suspected false-negative test results) compared with a representative po
81 ility testing using a collection of 297 Gram-negative bacilli, including members of the order Enterob
84 he MICs of CFDC were determined for 610 Gram-negative bacilli, including 302 multinational Enterobact
86 wn requirements for PIC targeting are a Gram-negative cell envelope and a unique cell surface antigen
89 ore cephalosporin with activity against Gram-negative bacterial species that are resistant to carbape
90 folding is an essential process in all Gram-negative bacteria, and considering the looming crisis of
92 ibit both gram-positive (S. aureus) and gram-negative (E. coli) bacteria on solid and porous surfaces
94 phylococcus aureus bacteremia (SAB) and gram-negative bacteremia (GNB) to compare the characteristics
95 ilters quickly killed Gram-positive and Gram-negative bacteria aerosols in vitro, with CFU reductions
97 The proportion of Gram-positive and Gram-negative bacteria were 135(68.2%) and 63(31.8%) respecti
99 for Gram-positive Bacillus subtilis and Gram-negative Escherichia coli as model organisms to monitor
101 80% of prostatitis cases are caused by Gram-negative uropathogenic Escherichia coli (UPEC) or Gram-p
104 HCT subjects were studied (7.5% develop gram-negative infection), with 4,768 fecal samples for analys
105 microbial resistance phenotypes, during Gram-negative bacterial infection and will advance our unders
107 lly efficacious therapy for fermenting, gram-negative bacteria in blood culture(s) if they were afebr
108 a high-throughput scRNA-seq method for Gram-negative and Gram-positive bacteria that can resolve het
110 isoprenoid synthesis, is essential for Gram-negative bacteria, mycobacteria and apicomplexans(2,3).
114 portant cell surface polysaccharides in gram-negative bacteria where they extend core lipopolysacchar
115 alent cause of antibiotic resistance in Gram-negative bacteria, i.e., the deactivation of the most wi
117 LPS transfection; however, its role in Gram-negative bacteria-mediated NLRP3 inflammasome activation
122 ivity against multidrug-resistant (MDR) Gram-negative pathogens as the pipeline of antibiotics is ess
123 monoderm) and those with two membranes (Gram-negative or diderm) is a fundamental open question in th
125 captures single-cell transcriptomes of Gram-negative and Gram-positive bacteria with high purity and
127 The asymmetric outer membrane (OM) of Gram-negative bacteria functions as a selective permeability
128 The highly asymmetric outer membrane of Gram-negative bacteria functions in the defense against cytot
133 the decoration of the outer surface of gram-negative bacteria with proteins tethered to the outer me
134 ), a component of the outer membrane of gram-negative bacteria, disrupts the alveolar-capillary barri
137 use our findings to propose a model of Gram-negative cell envelope stabilization that includes cell
138 study investigated the inactivation of Gram-negative Escherichia coli (E. coli) and Gram-positive En
141 nce genes, and both Pan Candida and Pan Gram-Negative targets that are unique to the BCID-GP Panel.
145 stic and frequently multidrug-resistant Gram-negative bacterial pathogen that primarily infects criti
148 prokaryotes, and in particular, several Gram-negative bacterial pathogens including Neisseria meningi
149 eered to attach specifically to several Gram-negative organisms, including the human pathogens Escher
150 re covalently attached to PG in several Gram-negative species, including Coxiella burnetii, Agrobacte
155 regate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli However, the physiol
157 s spanning different classes within the Gram-negative phylum Proteobacteria: Agrobacterium tumefacien
162 rial including adults hospitalized with gram-negative bacteremia conducted in 3 Swiss tertiary care h
163 stion "Does transitioning patients with gram-negative bloodstream infections from intravenous to oral
164 pared to the cell-grown vaccine but the H3N2-negative population had significantly greater titers to
165 gration of intrahepatic HBV DNA in the HBeAg-negative stage may be higher than previously anticipated
167 lantation of 30 HCV-viremic kidneys into HCV-negative recipients, followed by early initiation of an
170 an epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer represents a major mil
171 an epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who had received <=2 c
172 an epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer with prior clinical be
173 lly or cytologically confirmed advanced HER2-negative breast cancer, an Eastern Cooperative Oncology
174 iscrimination between HER2-positive and HER2-negative tumors as early as 2 h after injection (tumor-t
176 Premenopausal women with HR-positive/HER2-negative breast cancer and high recurrence risk, as defi
177 Overall, 202 untreated patients with HER2-negative AEGC and a Zubrod performance status of 0-1 wer
180 from 1802 human immunodeficiency virus (HIV)-negative children aged 1-59 months enrolled in the Pneum
186 l load) were virally suppressed, and 673 HIV-negative men (40% of 1673) were circumcised in intervent
188 ed 3 rapid urine tests in 372 ambulatory HIV-negative individuals suspected of having TB in South Afr
190 ype IV-B, was the most prevalent in both HIV-negative (38% at baseline, 30% at the follow-up visit) a
191 mong 598 HIV-positive and 550 comparable HIV-negative participants aged >= 45 years of the AGEhIV Coh
192 In both high- and low-income countries, HIV-negative children born to HIV-positive mothers (HIV expo
193 ch therapy with dolutegravir in healthy, HIV-negative adults was halted early after two of the four p
194 s are required to match drug exposure in HIV-negative patients.Conclusions: Weight-based dosing of ri
195 %, led to specificities of 91.3-95.3% in HIV-negative women and 77.0-85.8% in HIV-positive women.
197 ithelial neoplasia grade 2 or greater in HIV-negative women using manufacturer-defined cycle threshol
201 CD4 T cells from the blood and rectum of HIV-negative (HIV(-)) and antiretroviral therapy (ART)-suppr
204 Consecutive PLWH (n = 169) and at-risk HIV-negative individuals (n = 126) were recruited from 2 US
205 with anal precancer in HIV+ and at-risk HIV-negative women from the Atlanta Women's Interagency HIV
207 eople known to be HIV-positive or tested HIV-negative in the preceding 12 months; proportion of peopl
208 or guardian, and individuals who tested HIV-negative within the past 3 months but who reported a rec
209 nce interval [CI], -2.8 to .1) less than HIV-negative individuals during the first 2 months of tuberc
212 partnerships where both individuals were HIV-negative, we compared observed concordance in preexposur
219 ut compared to converters, persistently IGRA-negative contacts produced more proinflammatory cytokine
227 plays a crucial role in the survival of LEE-negative STEC as well as inducing apoptosis of the host
228 one marrow, CSF1R-FRed was absent in lineage-negative hematopoietic stem cells, arguing against a dir
229 cultured erythroid progenitor cells from MAM-negative individuals show markedly increased proliferati
232 ere 72% and 84% for ITT, 85% and 91% for MRD-negative patients, and 57% and 72% for patients with hig
237 hing sample, this benefit persisted for node-negative women (HR 0.80 [95% CI 0.66-0.97]; p=0.007), no
239 deconvolution analysis by implementing a non-negative linear least-squares fitting algorithm in conju
241 nalysis, independent component analysis, non-negative matrix factorization, t-distributed stochastic
242 A valid dwell time solution should be non-negative and duplicate the shape of the desired removal
244 fragmentation patterns via unsupervised non-negative matrix factorization and quantifies the reprodu
245 mtDNA depletion and cytochrome c oxidase-negative cells were found ex vivo in biopsies of affecte
246 itor pevonedistat decreased growth of Rb/p53-negative patient-derived cell lines and mouse xenografts
248 case series of 12 patients with culture/PCR-negative body fluids but for whom an infectious diagnosi
249 native viral infections in SARS-CoV-2 RT-PCR-negative PUIs (n = 30) and viral coinfections in SARS-Co
252 PET scans (n = 103), the 5-year TTP for PET-negative cases by Deauville criteria (D1-D3, DX) was 91%
256 LB as case study, we monitored healthy (qPCR-negative) in-field grown citrus trees and compared their
257 atistical analysis, we also showed that qPCR-negative plants exhibited HLB-specific spectral characte
258 out mice, and receptor-positive and receptor-negative intercalated cells from the same knockout mice.
259 ecimen was spiked into pooled SARS-CoV-2 RNA-negative specimen remnants for the various medium types.
260 Virulence inhibitory activity in the RND-negative background resulted from OmpR repression of the
265 connectivity between task-positive and task-negative networks in pediatric OCD may contribute to the
266 ll, binding across both tau-positive and tau-negative non-Alzheimer disorders did not reliably corres
280 et assays indicated that 8a decreases triple-negative breast cancer cell viability, and immunoblottin
281 ma (T98G) and a high ABCB1 expressing triple-negative breast cancer cell line (MDA-MB-231-luc) were t
282 y stage bone and lung metastasis from triple-negative breast cancer that should be given prior to con
283 iety of cancer cells, including human triple-negative breast cancer (TNBC) and patient-derived TNBC c
286 specific to tumor-initiating cells in triple-negative breast cancer xenografts that rely on LEFTY1 fo
287 ly recurrent inoperable or metastatic triple-negative breast cancer using a block method (block size
291 maintain the mesenchymal phenotype of triple-negative breast cancer cells and that CBFbeta-depleted c
293 OTULIN or Wnt/beta-catenin sensitizes triple-negative breast cancer xenograft tumors to chemotherapeu
294 f ZEB1 in basal-like tumor cells, two triple-negative breast cancer (TNBC) subtypes, to demonstrate t
295 roved prospective study, a woman with triple-negative breast cancer (age, 49 years) underwent (13)C M
297 sitive for cancer; and 264 patients had true-negative findings based on follow-up imaging for a minim
298 tached vitreous at the time of surgery (true-negative results), and 8 eyes had pre-existing PVD at th