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1 ow-level viremia that persists in most HIV-1-positive individuals on antiretroviral therapy (ART) is
2 were found to accumulate in TNC-C and NRP-1-positive areas in clinical tumor samples, suggesting a t
4 of matriglycan, retention of synaptotagmin-1-positive EYS secretory vesicles within the outer nuclear
6 degradation pathway and instead enter Rab 11-positive recycling endosomes, where they are returned to
7 vaccine history, 1,561 (47%) were HPV-16/18-positive, 136 (4%) received 1 dose of HPV vaccine, 108 (
8 e direct target sites of E2A-PBX1 in t(1,19)-positive pre-B ALL cells and show that, compared with no
11 immunoglobulin M in 87% (52 of 60) COVID-19-positive serum samples collected 6 or more days after sy
12 of glucagonlike peptide 1 receptor (GLP-1R)-positive lesions, using the GLP-1 agonist exendin-4 labe
16 r, pulmonary vascular engraftment of miR-210-positive interstitial lung macrophages was observed in k
17 llular localization by directing it to Rab 5-positive (Rab 5(+)) vesicles and targeting it for seques
18 stinal epithelial cells, with chromogranin A-positive enteroendocrine cells (EECs) identified as a pe
20 near-normal density of acetylcholinesterase-positive process arborization, which was significantly i
21 use oocytes results from a gradient of actin-positive vesicle activity and is essential for developme
23 tability and robustness of networks with all-positive interactions by studying the distribution of th
24 ain-/- human signal regulatory protein alpha-positive (RRGS) rats combining Rag1 and Il2rg deficiency
26 tion of T cells induced cytolysis of antigen-positive HCC cells and cells infected with HBV in vitro,
27 ts were anti-HIV/hepatitis B surface antigen-positive adults from eight clinical sites in the United
28 therapy-independent outcomes of autoantibody-positive patients without encephalitis suggests immunoth
32 ime, we observed that the proportion of BrdU-positive ZCs remained greater than 60% up to 11 months.
33 tribution properties in mouse models of CAIX-positive clear cell renal cell carcinoma (ccRCC) and col
37 11 patients with relapsed or refractory CD19-positive cancers (non-Hodgkin's lymphoma or chronic lymp
38 =18 years) had histologically confirmed CD20-positive relapsed or refractory non-Hodgkin lymphoma, ha
40 tic large-cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lym
43 istence and a terminally differentiated CD39-positive state (CD39(+)CD69(+)) associated with poor TIL
48 e platelet-derived CD61-positive EVs and CD9-positive EVs, isolated by IAC, were further fractionated
49 analysis in patients with PD-L1 immune cell-positive tumours, median overall survival was 25.0 month
52 rence, and 28% of patients had (11)C-choline-positive suspected recurrences outside the initial treat
55 ce Plus MP identified 93.3% of the confirmed-positive specimens, whereas 83.6, 64.6, and 55.7% were i
58 tibody-negative, endothelial cell crossmatch-positive sera obtained from 12 cardiac allograft recipie
61 ositive in 27/5,594 (0.5%) bacterial culture-positive anaerobic bottles that contained cultures colle
62 Change in clinical management for culture-positive eyes was based on declining vision (3 eyes), wo
64 analyzed Mycobacterium tuberculosis culture-positive cases reported to the National TB Surveillance
65 ive for diphtheria toxin gene, 1 was culture-positive without further testing, and the remaining 3 we
67 S. epidermidis-colonized screws were culture-positive and displayed minor changes in peri-implant bon
72 a lower rate of somatic mutation, whereas D3-positive tumors were less likely to integrate, had later
77 the TCGA database indicated a higher double-positive signal in basal-like breast cancer than in lumi
80 gene (ESR1) mutations occur frequently in ER-positive metastatic breast cancer, and confer clinical r
81 med on the MCF-7 breast cancer cell line (ER-positive and HER(2)-negative) demonstrated specific upta
82 en associated with disease progression of ER-positive breast cancer patients and resistance to tamoxi
83 ter clinical outcome in tamoxifen treated ER-positive breast cancer patients by repressing estrogen s
85 In a cohort of postmenopausal women with ER-positive DCIS, preoperative letrozole resulted in signif
87 RFI1 is selectively downregulated in ERalpha-positive breast cancers and breast cancers driven by ERB
93 ent, lower associated morbidity, fewer false-positive and false-negative results, lower-cost, and hig
96 t have their drawbacks, including high false-positive rates and limited antibody availability, respec
98 ved as a result of screening, and many false-positive results required additional, subsequent MRI sca
102 ry prostate cancer, an equal number of false-positive lesions was observed among the different recons
103 ficiency with a negligible increase of false-positive risk, it contains several step-by-step operatio
105 architectures are capable of producing false-positive rates that are orders of magnitude lower than a
109 irus and SARS-CoV-2, which can lead to false-positive dengue serology among COVID-19 patients and vic
114 Viral genome sequencing of the paired first-positive and reinfection viral specimens was conducted t
115 stration of a neutralizing/effector function-positive bNAb via the airway and systemic routes showed
117 nti-tumour activity against NTRK gene fusion-positive solid tumours, including CNS activity due to it
119 even [10%] of 68 patients in the NTRK fusion-positive safety population and in 18 [5%] of 355 patient
120 (six [86%] of 7 patients) and PDGFRB fusion-positive B-cell acute lymphocytic leukaemia (43 [88%] of
122 d Feb 19, 2019, 159 patients with TRK fusion-positive cancer were enrolled and treated with larotrect
124 Methods Consecutive women and men with gene-positive Fabry disease who had undergone cardiac MRI at
126 +/-SE: 2.1+/-0.7, P<0.002) and LQTS genotype-positive family members (87.5+/-7.4, difference-in-mean,
131 ile horine was potent primarily against gram-positive pathogens, verine showed broad-spectrum antimic
134 tments have the ability to inhibit both gram-positive (S. aureus) and gram-negative (E. coli) bacteri
135 yeast cells and various strains of both Gram-positive and -negative bacteria revealed distinct bindin
136 is a rare, chronic, infection caused by gram-positive filamentous aerobic actinobacterium Tropheryma
138 oposed EAST is successfully applied for Gram-positive Bacillus subtilis and Gram-negative Escherichia
140 a benzisoxazole scaffold with improved Gram-positive antibacterial activity relative to previously d
142 hol species are important Fe sources in Gram-positive human pathogens, since PiuA functions in the sa
143 t-functionalized filters quickly killed Gram-positive and Gram-negative bacteria aerosols in vitro, w
144 tween cell envelopes with one membrane (Gram-positive or monoderm) and those with two membranes (Gram
145 This modification occurs in numerous Gram-positive pathogens, including methicillin-resistant Stap
148 ent antibiotic against a broad range of Gram-positive bacteria, but its medical applications have bee
149 ly used clinically for the treatment of Gram-positive skin and skin structure infections (SSSI), Stap
150 general blueprint for the conversion of Gram-positive-only compounds into broad-spectrum antibiotics.
151 ycin, an antibiotic that acts mainly on gram-positive bacteria and is restricted to the gut, potentia
152 coagulase-negative staphylococci, other gram-positive, and gram-negative bacteria, respectively.
153 ighly effective approach for preventing gram-positive cocci-related, skin flora-related, or central l
155 have one pathway or the other, but the Gram-positive, facultative intracellular pathogen Listeria mo
156 des when the flies were challenged with Gram-positive bacteria Micrococcus luteus In this setting, os
159 an epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer who have disease progr
160 ted in excellent discrimination between HER2-positive and HER2-negative tumors as early as 2 h after
161 onium 89 ((89)Zr)-pertuzumab can depict HER2-positive metastases in women with HER2-negative primary
162 umab PET/CT was successful in detecting HER2-positive metastases in women with HER2-negative primary
165 stuzumab and chemotherapy in first-line HER2-positive metastatic oesophagogastric cancer is underway.
166 e identifies patients with early-stage, HER2-positive breast cancer who might be candidates for escal
171 erapies are successful in patients with HER2-positive malignancies; however, spatial and temporal het
172 We randomly assigned patients with HER2-positive metastatic breast cancer previously treated wit
174 ears of follow-up was assessed among 598 HIV-positive and 550 comparable HIV-negative participants ag
175 ehavioral changes on HCV incidence among HIV-positive GBM up to 2025 using a HCV transmission model p
177 aseline, 30% at the follow-up visit) and HIV-positive (27% at baseline, 35% at the follow-up visit) w
178 101 individuals were newly identified as HIV-positive out of 1248 total individuals who were HIV-posi
179 er who were not previously identified as HIV-positive, children younger than 15 years who reported be
180 ured by proportion of people known to be HIV-positive or tested HIV-negative in the preceding 12 mont
181 linical guidelines, and higher doses for HIV-positive patients should be considered to provide equiva
185 lity associated with mental disorders in HIV-positive people in South Africa, adjusting for HIV treat
186 cell count, pregnancy incidence rates in HIV-positive women receiving ART were higher than those in u
189 g positive) identified through screening HIV-positive inpatients with sputum and urine diagnostics in
192 ing individuals who are unaware of their HIV-positive status in combination with monitoring the previ
193 countries, HIV-negative children born to HIV-positive mothers (HIV exposed, uninfected [HEU]) are mor
194 ART were higher than those in untreated HIV-positive women (adjusted hazard ratio, 1.63; 95% confide
196 e out of 1248 total individuals who were HIV-positive, representing an 8.1% previously unidentified f
198 ia standardised paper-based surveys with HIV-positive adults who were neither pregnant nor breastfeed
201 uated MPTP-induced CSF1R activation and Iba1-positive cell proliferation, without a reduction of the
203 sual outcomes in a large series of CRMP5 IgG-positive patients to characterize further its clinical p
205 mate was 89% (95% CI, 82% to 94%), with iPET-positive and iPET-negative patients having similar outco
207 r geometric mean titers than mothers of KSHV-positive children; however, there was no difference in t
208 le), and response rates were higher in PD-L1-positive (8/28; 29%) versus PD-L1-negative (0/12; 0%) pa
212 ll substrates are transported via large M6PR-positive vacuoles without degradative xenophagy to the p
213 s lack a VZV trafficking pathway within M6PR-positive large endosomes and (ii) most infectious VZV pa
214 After secondary review, 91.1% of manual-positive/automation-negative specimens were due to exper
219 g intra-striatal delivery, pathological mHTT-positive protein aggregates were distributed widely amon
220 Ectopic expression of Cxcl9l recruits mpeg1-positive macrophages to bone matrix and triggers their d
222 ) were found to be MRD negative, and the MRD-positive patients experienced early subsequent relapse.
223 n patients with MET-amplified, EGFR mutation-positive, advanced NSCLC, who had disease progression on
231 f second-generation GluN2C/D-selective NMDAR-positive allosteric modulators (PAMs) with a dihydropyrr
232 (HR 0.80 [95% CI 0.66-0.97]; p=0.007), node-positive women (0.76 [0.64-0.91]; p=0.006), and those wi
233 erative systemic chemotherapy exposure, node-positive primary status, and size of largest liver metas
234 ible patients were those with operable, node-positive-or node negative with tumor 1 cm or greater-TNB
235 e consistent with the detection of norovirus-positive EECs in the other three immunocompromised patie
237 further detected a significant loss of OLIG2-positive cells in the corpus callosum of Tmem106b-/- mic
238 t precautions to standard precautions for Pa-positive patients with a surveillance screening program
239 s overactivated in corticolimbic parvalbumin-positive GABAergic interneurons in Grin1 mutant mice.
240 and progressive degeneration of parvalbumin-positive (PV(+)) neurons in substantia nigra pars reticu
241 l excision showed Periodic acid Schiff (PAS)-positive eosinophilic structures inside macrophages.
243 re and Elek, 6 were culture-negative but PCR-positive for diphtheria toxin gene, 1 was culture-positi
244 tive virus was later sequenced from a RT-PCR-positive individual and assessed using phylogenetic anal
246 A total of 104 individuals had an RT-PCR-positive viral test with a cycle threshold (C(T) ) of <3
247 For culture-negative samples, mean cost-per-positive 16S PCR result was pound 568.37 and pound 292.8
249 was calculated as the proportion of PSMA PET-positive patients to all patients independent of the ref
250 atory gene CDK6 is required for Philadelphia-positive (Ph+) acute lymphoblastic leukemia (ALL) cell g
251 ut was 530-fold less infectious than plasmid-positive Chlamydia, suggesting that (i) the noninfectiou
253 vor somatostatin- and pancreatic polypeptide-positive cells at the expense of insulin- and glucagon-p
256 ely in PET-2, we observed a total of 15 PSMA-positive spots in the bone marrow of 6 patients (22%).
258 and in 4 patients additional suspected PSMA-positive lesions were identified (1 patient changed from
260 ing agents to target PSMA and visualize PSMA-positive tumor lesions as shown in preclinical evaluatio
261 and cellular properties of parvalbumin (PV)-positive CINs were altered by the loss of Nf1, without c
266 wild-type mice, knockout mice, and receptor-positive and receptor-negative intercalated cells from t
269 CDK) 4 and 6 inhibitors for hormone receptor-positive and human epidermal growth factor receptor 2 (H
271 proved for the treatment of hormone-receptor-positive metastatic breast cancer following antiestrogen
272 n of Vegfc in endothelial or leptin receptor-positive (LepR+) cells led to a disruption of the BM per
273 Mice bearing CA20948 somatostatin receptor-positive tumor xenografts were treated with (177)Lu-DOTA
276 Compared to RSV-negative ARI cases, RSV-positive cases were associated with cough, apnoea and ho
278 undred four DNA samples extracted from smear-positive sputum sediments, previously sequenced using th
279 -label trial in which individuals with smear-positive pulmonary TB with isoniazid resistance mediated
287 ests with follow-up ultrasonography for test-positives, (2) the enhanced liver fibrosis (ELF) test wi
291 tatic niche created in the lymph node of TRL-positive patients misleads 18F-FDG-PET/CT for detecting
292 rcentage of patients who had at least 1 true-positive PSMA PET lesion localized that corresponded wit
296 omID, the sensitivity was 100%, with no true-positive GBS isolates missed by 48 h of incubation.
297 re-existing PVD at the time of surgery (true-positive results), and 18 eyes were found to have attach
299 However, in up to 18.6% of patients, tumor-positive resection margins are detected on histopatholog
300 transferase dUTP nick end labelling (TUNEL)-positive dying cells and reduced infarct growth from 12