ライフサイエンスコーパス: -seeking

1 ing responses for alcohol; (2) after alcohol-seeking behavior was well established; and (3) after the

2 itazone reduces alcohol drinking and alcohol-seeking behavior in rats.

3 subsequent development of compulsive alcohol-seeking behavior.

4 r that is associated with compulsive alcohol-seeking behavior.

5 during extinction of cue-conditioned alcohol-seeking behavior.

6 acilitate long-lasting extinction of alcohol-seeking behavior.SIGNIFICANCE STATEMENT Alcohol use diso

7 Only alcohol-seeking, not alcohol-taking, responses became dependent

8 pecific ALDH2 inhibition can prevent alcohol-seeking behavior.

9 ow how different forms of relapse to alcohol-seeking are assembled from VP cell types and their proje

10 ow how different forms of relapse to alcohol-seeking in male rats are assembled from activity across

11 rent VP cell types during relapse to alcohol-seeking provoked by renewal (context-induced reinstateme

12 Here we show how relapse to alcohol-seeking relates to activity in specific VTA and accumben

13 H neurons in two forms of relapse to alcohol-seeking: renewal (context-induced reinstatement) and rea

14 of exendin-4 that reduced opioid-taking and -seeking behaviors and did not produce adverse feeding ef

15 tly established models of opioid-taking and -seeking behaviors, we showed that systemic administratio

16 houlder dislocations are a form of attention-seeking.

17 y help account for the tendency for audience-seeking news around the world to be predominantly negati

18 N-glycans, which were up-regulated in brain-seeking cell line 231BR, likely play a role in brain met

19 chanisms that give rise to aberrant cannabis-seeking behavior.

20 t of volitional cannabis intake and cannabis-seeking behaviors.SIGNIFICANCE STATEMENT The evolving le

21 urst and an increase in cue-induced cannabis-seeking behavior relative to VEH.

22 diagnosis, patient characteristics, and care-seeking patterns associated with missed diagnosis.

23 ry 2017 and February 2019, to ascertain care-seeking behavior for individuals with 1) fever for >=3 c

24 re at ages 1-14 years, and increases in care-seeking among horizontally infected adolescents aged 15-

25 by province, to respond to variances in care-seeking patterns and the capacities of public and privat

26 rian economic recession that influenced care-seeking and hospital function during the study period, p

27 nerated content to characterize patient care-seeking context which could ultimately enable better all

28 which were effective in attenuating cocaine-seeking behavior.

29 and an inverse relationship between cocaine-seeking activity and subsequent cocaine motivation.

30 e strongest in the most compulsively cocaine-seeking individuals, this may also indicate that VP play

31 ng the acquisition of cue-controlled cocaine-seeking behavior have not been elucidated.

32 or the acquisition of cue-controlled cocaine-seeking behavior.

33 ly activated (indexed by Fos) during cocaine-seeking tests after 0 (no-extinction) or 7 extinction se

34 d efficiently protects the mice from cocaine-seeking behavior and cocaine overdose.

35 displayed a significant reduction in cocaine-seeking behavior compared to rats housed in isolation.

36 ry for nicotine-induced increases in cocaine-seeking, and that D2 receptors and CX3CL1 play a mechani

37 idation reduced drug context-induced cocaine-seeking behavior 3 d, but not three weeks, later.

38 (1) subsequent drug context-induced cocaine-seeking behavior as well as (2) cellular adaptations and

39 nd significantly reduced cue-induced cocaine-seeking behaviors in rats.

40 dministration and reduce cue-induced cocaine-seeking behaviors.

41 hell inhibited cue- and drug-induced cocaine-seeking, respectively.

42 ng abstinence attenuated cue-induced cocaine-seeking.

43 ne to attenuate the reinstatement of cocaine-seeking and assessed reinstatement-induced Fos expressio

44 ting extinction and reinstatement of cocaine-seeking and perform detailed characterization of its pro

45 l area (VTA) in the reinstatement of cocaine-seeking behavior, an animal model of relapse.

46 rug context-induced reinstatement of cocaine-seeking behavior.

47 ne, and it facilitated extinction of cocaine-seeking behavior.

48 gion that controls the expression of cocaine-seeking behavior.

49 designer drugs) during a variety of cocaine-seeking behaviors, revealing nuanced, pathway-specific r

50 amate efflux during reinstatement of cocaine-seeking.

51 NA) core during the reinstatement of cocaine-seeking.

52 essive effects of GLP-1R agonists on cocaine-seeking behavior are largely unknown.

53 NorBNI did not induce or potentiate cocaine-seeking behavior induced by OrxA but reversed DynA effec

54 iated contextual memories can reduce cocaine-seeking behavior, however the molecular mechanisms withi

55 n the nucleus accumbens, and reduced cocaine-seeking behavior.

56 lves a new form of learning, reduces cocaine-seeking behavior; however, the molecular mechanisms unde

57 s a robust intervention for reducing cocaine-seeking behaviors in animals when given during forced ab

58 d forebrain nuclei known to regulate cocaine-seeking behavior.

59 sure to drug-related cues reinstated cocaine-seeking behavior and increased AMPK and p70s6k phosphory

60 te or pathogen, the host may respond by cold-seeking behavior.

61 the autonomic cold defense and for the cold-seeking response to LPS, we studied rats with small ther

62 Therefore, cold-seeking behavior is beneficial to F. occidentalis when i

63 This cold-seeking behavior suppressed the growth of B. bassiana in

64 Compensation-seeking populations predominate in the PVT literature.

65 he et al. argue that affiliation and contact-seeking are key responses to danger.

66 Cool-seeking behaviour was determined from total time receivi

67 demonstrate that skin wetness augments cool-seeking behaviour during passive heat stress independent

68 hat elevations in skin wetness augments cool-seeking behaviour during passive heat stress.

69 etness enhances the desire to engage in cool-seeking behaviour during passive heat stress.

70 kin wetness amplifies the engagement in cool-seeking behaviour during passive heat stress.

71 iscomfort, the precursor to engaging in cool-seeking behaviour.

72 indicates that skin wetness stimulates cool-seeking behaviour to a greater extent than increases in

73 pendent contribution of skin wetness to cool-seeking behaviour during heat stress has never been esta

74 ging of IL-NAc neurons in rats during a drug-seeking test.

75 o decrease consumption, withdrawal, and drug-seeking associated with several drugs of abuse and thus

76 uch as ethanol, can trigger craving and drug-seeking behavior.

77 aptive plasticity that drives food- and drug-seeking behaviors.

78 xperience-dependent neuroplasticity and drug-seeking behaviors.

79 alterations to these genes may augment drug-seeking.

80 s "novelty-seeking" predicts compulsive drug-seeking behavior.

81 ceptual distinctions between compulsive drug-seeking behaviour and compulsive drug-taking behaviour (

82 addiction is associated with compulsive drug-seeking, and exposure to the drug or to drug-associated

83 ble rates of responding and conditioned drug-seeking behavior.

84 h the ability of multiple cues to drive drug-seeking behavior after just one reactivation and treatme

85 xual context appears to enhance further drug-seeking behavior.

86 However, drug-seeking behavior was significantly higher in concurrent

87 Next, drug-seeking behaviors were measured during cue reactivity, e

88 , but not cue-induced, reinstatement of drug-seeking behavior, whereas inhibition of SNr GABA neurons

89 and may have a role in the etiology of drug-seeking behavior.

90 ence of Meth triggered reinstatement of drug-seeking in concurrent animals.

91 ine and stress-induced reinstatement of drug-seeking.

92 in drug-taking and the reinstatement of drug-seeking.

93 stration (SA) underlie reinstatement of drug-seeking.

94 The influence of social cues on drug-seeking behavior has garnered attention recently, but fe

95 T2) neurons have contrasting effects on drug-seeking behavior, our data may indicate a complex role f

96 erative to BDNF's suppressive effect on drug-seeking.

97 d hyperkatifeia, which drive pronounced drug-seeking behavior via processes of negative reinforcement

98 GR127935 was most effective in reducing drug-seeking on ED1, whereas betaxolol/ICI-118 551 was ineffe

99 Yet how relapse to drug-seeking is assembled from activity across the mesolimbic

100 ade of MORs in the VTA counteracted two drug-seeking behaviors, locomotor activity and place preferen

101 osensory behavior: each is important for dry-seeking by hydrated flies and together they underlie moi

102 However, those roles for ethanol-seeking behaviors remain unknown.

103 aversive stimuli and plays a role in ethanol-seeking behavior.

104 To investigate ethanol-seeking behaviors, we used an ethanol-containing reward

105 ional state (v = 0) and the lowest low-field-seeking quantum state.

106 duced food intake, food-motivation, and food-seeking, while blocking endogenous PVT GLP-1R signaling

107 ally inactivated during consumption and food-seeking.

108 to escape from the stressful condition: food-seeking roaming mediated by the opioid peptide NLP-24 an

109 he VTA (mNAc->VTA) are inhibited during food-seeking and food consumption in male mice.

110 When motivation for food-seeking competes with avoidance of danger, the PFC likel

111 The target article addresses increased food-seeking behaviors in times of instability, particularly

112 of NAc projections to the VTA inhibits food-seeking and food intake (in both sexes), while optogenet

113 ty of postingestive signals to modulate food-seeking behaviors.

114 hese compounding selection pressures on food-seeking motivation during breeding, as well as the hormo

115 inhibition of this circuit potentiates food-seeking behavior.

116 well balanced for all covariates and health-seeking behavior indicators.

117 d from each study area to investigate health-seeking behaviour in cases of self-reported fever lastin

118 aby's bedside as a driver of maternal health-seeking behaviors, with women not seeking or delaying me

119 ing reports, population biases in the health-seeking behaviour, and the lack of a common definition o

120 vey was administered to ascertain healthcare-seeking behavior in individuals with recent suspected en

121 Characterizing healthcare-seeking patterns for acute febrile illness is critical f

122 racterize differences in outcomes among help-seeking individuals at clinical high risk for psychosis

123 spent trying, trying force, affect, and help-seeking behaviour on the task.

124 ollowed by tailored advice would modify help-seeking behaviour.

125 nsitivity, targeting individuals in non-help-seeking samples based only on more severe symptom cutoff

126 Replicable subgroups of help-seeking clinical high-risk cases can be ascertained base

127 ated research into the underpinnings of help-seeking individuals at risk for developing psychosis, ai

128 ication Test (AUDIT), and self-reported help-seeking from clinical and welfare providers comparing th

129 rescribing behaviour, or young people's help-seeking behaviour.

130 ient participation in cancer screening, help-seeking for new and/or changing symptoms and clinicians'

131 e, the field has progressed to studying help-seeking individuals who are at clinical high risk based

132 icothalamic projections did not alter heroin-seeking behavior.

133 eural plasticity, reduce alcohol- and heroin-seeking behaviour, and produce antidepressant-like effec

134 in the encoding of heroin-taking and heroin-seeking in rats.

135 self-administration context for a 3 h heroin-seeking test under extinction conditions during which co

136 ing vulnerability to reinstatement of heroin-seeking and provide insight into the specific neurobiolo

137 cerbates cue-induced reinstatement of heroin-seeking in high- but not low-risk rats, again with no ef

138 pressing cue-induced reinstatement of heroin-seeking in high- but not low-risk rats.

139 feeding may be important in Ae. aegypti host-seeking activity and thus can be candidates for mosquito

140 hemically similar to host plants affect host-seeking or ovipositional behavior of swede midge?

141 hat infected mosquitoes exhibit altered host-seeking behaviours, with suppression and activation of b

142 on, these odorants elicit attraction by host-seeking mosquitoes, emphasising that Ors alone can media

143 Understanding mechanisms of endogenous host-seeking suppression may allow them to be 'weaponized' ag

144 primary and non-redundant role in human host-seeking behaviors.

145 Exhaled CO(2) is an important host-seeking cue for Anopheles mosquitoes, which is detected

146 from different plant species influence host-seeking and oviposition behaviors of swede midge?

147 dless of CO(2) stimulation and internal host-seeking status.

148 g human NPY receptors modulate mosquito host-seeking.

149 mbine to produce the full expression of host-seeking suppression?

150 ge, the duration and extent of seasonal host-seeking activity increases in northern California, but d

151 nder a hotter, wetter scenario seasonal host-seeking declines in northern California, but increases i

152 ptors is important for species-specific host-seeking.

153 how environmental suitability for tick host-seeking changes seasonally, how the magnitude and direct

154 ibutions of human-associated stimuli to host-seeking decisions.

155 an-occupied spaces and interfering with host-seeking and blood-feeding.

156 -19 symptoms and prevention) and information-seeking behavior (number of web links demanded out of 10

157 tinx participants' knowledge and information-seeking behavior.

158 ationship between confidence and information-seeking.

159 signals first revealed that both information-seeking choices and decision confidence could be decoded

160 y the level of confidence and by information-seeking choices.

161 but did not significantly change information-seeking incidence.

162 e the diverse motives that drive information-seeking and its avoidance.

163 sy to compute quantity can drive information-seeking, potentially allowing simple organisms to intell

164 engage in such confidence-driven information-seeking.

165 ic valuation systems, in driving information-seeking behavior.

166 ing goal-oriented and epistemic (information-seeking) behaviours in a principled manner.

167 Here, we examine information-seeking responses to the first COVID-19 case public anno

168 both insufficient and excessive information-seeking.

169 ns, suggesting more exploratory, information-seeking gaze behavior.

170 , we show that the incentive for information-seeking can be separated from a long-term learning outco

171 wards and propose how they guide information-seeking, attention, decision-making, and learning to hel

172 nce are functionally involved in information-seeking decisions.SIGNIFICANCE STATEMENT Despite substan

173 ifying individual differences in information-seeking, which we hypothesize may also be diagnostic of

174 test for the role of dopamine in information-seeking.

175 -concordant physicians increased information-seeking incidence from 0.329 (for discordant physicians)

176 fidence should lead to increased information-seeking.

177 particular dopamine, to instruct information-seeking.

178 intentions and population-level information-seeking and this was mediated by activity in ventromedia

179 insight into the neurobiology of information-seeking and generates the prediction that abnormal dopam

180 g framework to capture styles of information-seeking in 149 participants as they explore Wikipedia fo

181 Here we propose a framework of information-seeking that aims to integrate the diverse motives that

182 reduces the impact of valence on information-seeking.

183 versus low confidence predicted information-seeking choices after the initial perceptual decision (a

184 on to the time of the subsequent information-seeking choice (within-condition decoding).

185 Biases in such information-seeking behavior can contribute to the maintenance of in

186 ecordings, we could predict such information-seeking choices based on a neural signature of decision

187 Here we show that information-seeking behavior in humans is driven by subjective value

188 n information and motivates this information-seeking behavior.

189 through monitoring the real-time information-seeking behaviors in the search engine queries, which ar

190 lue of information that leads to information-seeking or avoidance.

191 in valence-dependent changes to information-seeking.

192 ocognitive mechanisms underlying information-seeking behavior.

193 to explore mechanisms underlying information-seeking.

194 long-term learning outcome, with information-seeking best predicted by per-trial outcome uncertainty.

195 Here, we focus on light-seeking navigation in zebrafish larvae.

196 itness at the hands of nonprovisioning, mate-seeking "cads." Recent models require exacting interplay

197 ability of METH-associated memories and METH-seeking behavior to NMII inhibition within the BLA.

198 rated flies and together they underlie moist-seeking by dehydrated flies.

199 Nectar-seeking involves the integration of at least three senso

200 standing the neural basis of mosquito nectar-seeking behaviors.

201 understanding the molecular basis of nectar-seeking.

202 tly tested for sensation-seeking and novelty-seeking.

203 ty to alcohol-aversion and increased novelty-seeking, which may be relevant to excessive drinking.

204 eased social interaction, and social novelty-seeking).

205 l propensity to take drugs; whereas "novelty-seeking" predicts compulsive drug-seeking behavior.

206 behavioral phenotype correlated with novelty-seeking, impulsive response to reward, and vulnerability

207 lopment and persistence of compulsive opioid-seeking behavior.

208 s similarly regulate reinstatement of opioid-seeking remains unknown, as is their role in modulating

209 istration and the reinstatement of oxycodone-seeking behavior in rats.

210 istration and the reinstatement of oxycodone-seeking behavior without affecting ad libitum food intak

211 on responding and reinstatement of oxycodone-seeking behavior.

212 Here we studied how partner-seeking termites update their search strategies dependin

213 oraging and pollination behaviors, but plant-seeking and oviposition behaviors are sustained through

214 stigated the role of glutamate in pregabalin-seeking behavior with ceftriaxone (CEF), a potent GLT-1

215 involved in reinstatement of psychostimulant-seeking.

216 ation gathering (e.g., checking, reassurance-seeking), and uncertainty about possible, often catastro

217 on impaired inhibitory but not active reward-seeking, the latter effect being diametrically opposite

218 ork also plays a key role in adapting reward-seeking behavior when the contingencies linked to a cue

219 d insulin secretion, food intake, and reward-seeking behaviors.

220 in different aspects of avoidance and reward-seeking, but their respective contribution in instigatin

221 as required for Pavlovian conditioned reward-seeking and defensive behaviors.

222 rticipates in learning of conditioned reward-seeking behaviors.

223 and iMSNs regulate ethanol-containing reward-seeking behaviors.SIGNIFICANCE STATEMENT Our findings hi

224 Mice exhibiting ethanol-containing reward-seeking showed a reduction of the indirect medium spiny

225 y, mice exhibiting ethanol-containing reward-seeking showed the reduction of the DMS iMSNs activity,

226 perant conditioned ethanol-containing reward-seeking, whereas inhibiting this neuronal activity resto

227 -GPe iMSNs reduced ethanol-containing reward-seeking, whereas optogenetic inhibition of the DMS-GPe i

228 activation reduces ethanol-containing reward-seeking, which may provide a potential therapeutic targe

229 onist and restored ethanol-containing reward-seeking.

230 activity restored ethanol-containing reward-seeking.

231 ng that disinhibiting iMSNs decreases reward-seeking behaviors.

232 exposure potentiated A(2A)R-dependent reward-seeking.

233 sure potentiated the A(2A)R-dependent reward-seeking.

234 tum (DMS) in regulating goal-directed reward-seeking behavior has been long appreciated.

235 ifting from habitual to goal-directed reward-seeking behavior.

236 sition from habitual to goal-directed reward-seeking behaviors upon astrocyte activation, while resto

237 oped either habitual or goal-directed reward-seeking behaviors.

238 res an ability to coordinate discrete reward-seeking and reward-retrieval behaviors.

239 Cues can also promote dysfunctional reward-seeking behavior, as in overeating.

240 ch conditioned stimuli (CS) can guide reward-seeking behavior in adaptive (e.g., locating food) and m

241 Habitual reward-seeking behavior is a hallmark of addictive behavior.

242 xin system, leading to impairments in reward-seeking and active coping mechanisms.

243 henotype, unrelated to differences in reward-seeking and Pavlovian fear, and due to a failure of inst

244 ABA neurons facilitates adaptation in reward-seeking behaviors.

245 eciding whether and when to engage in reward-seeking rather than to decide which action to perform.

246 eciding whether and when to engage in reward-seeking rather than to decide which action to perform.SI

247 relevant inputs to accurately inform reward-seeking behavior.

248 motivational properties and initiate reward-seeking behaviors.

249 rons prevented cues from invigorating reward-seeking behavior, an effect that was mediated by activat

250 The amplification of reward-seeking behavior under uncertainty described by Anselme

251 uence of a reward-predictive cue over reward-seeking actions in male and female rats.

252 s) can have oppositional control over reward-seeking and associative learning and are critically invo

253 ulatory systems implicated in primary reward-seeking, in particular dopamine, to instruct information

254 concurrent assessment of punishment, reward-seeking, and Pavlovian fear.

255 irectionally altered rats' subsequent reward-seeking behavior.

256 ism by which VTA activity can support reward-seeking behaviors.

257 ganglia region functionally linked to reward-seeking behavior.

258 somedial striatum (DMS) contribute to reward-seeking behaviors.

259 ortical structures that contribute to reward-seeking behaviours, such as the ventral striatum and mid

260 e stimuli orient the attention toward reward-seeking, whereas instructive stimuli inform about the ac

261 nuates the ability of cues to trigger reward-seeking, while some aspects of the motivation for the re

262 uence motor decision-making and improve risk-seeking bias.

263 In addition to the effect on risk-seeking for gains, low-weight participants also exhibite

264 ss biases people to make risk-averse or risk-seeking decisions, respectively.

265 effect on impulsive choice, but reduced risk-seeking for gains in more-impulsive subjects.

266 (Macaca mulatta) appear to be robustly risk-seeking in computerized gambling tasks typically used fo

267 dly confirmed that humans show a strong risk-seeking bias, selecting a risky strategy over an optimal

268 e, the subjects robustly switched their risk-seeking strategy to a risk-averse strategy.

269 incentive salience attribution and sensation-seeking behavior that were not previously apparent.

270 eased opportunity for diversion by sensation-seeking users.

271 For example, "sensation-seeking" is predictive of the initial propensity to take

272 ing'), and subsequently tested for sensation-seeking and novelty-seeking.

273 ng studies have largely focused on sensation-seeking traits and approach behavior, the neural substra

274 ed reinstatement of cocaine- but not sucrose-seeking behavior.

275 t food, cue-induced reinstatement of sucrose-seeking, and motivation to work for sucrose were employe

276 ituting the cocaine- compared to the sucrose-seeking ensemble.

277 ate-dependent expression of water- and sugar-seeking memories.

278 ces of excessive sun exposure, modifying sun-seeking behavior is challenging because it appears to be

279 In a GWAS meta-analysis of sun-seeking behavior in 261,915 subjects of European ancestr

280 ated education effort can improve transplant-seeking behaviors and waitlisting rates.

281 Treatment-seeking adults aged 18-65 years who had moderate or seve

282 The sample included 97 treatment-seeking adult men with GD, diagnosed according to DSM-5

283 ich moderate drinkers (N = 30) and treatment-seeking individuals with alcohol use disorder (AUD: N =

284 istic framework reflecting complex treatment-seeking pathways.

285 ticipants and 156 medication-free, treatment-seeking patients with anxiety) completed a differential

286 ment and its prognostic utility in treatment-seeking adult outpatients with major depressive disorder

287 ulation, and significant shifts in treatment-seeking behaviour following implementation of a new anti

288 r population growth and changes in treatment-seeking behaviour, the incidence of P. falciparum malari

289 In treatment-seeking populations, opioid agonist therapy and naltrexo

290 y derived from trials conducted in treatment-seeking populations.

291 82; replication: n = 326) included treatment-seeking youth with anxiety disorders, with disruptive mo

292 laria spending, as well as malaria treatment-seeking, costs of patient care, and drug prices.

293 A total of 48 non-treatment-seeking heavy drinkers (16 women) who met DSM-IV criteri

294 Fifty-six, non-treatment-seeking heavy drinkers, with alcohol dependence and a po

295 tal and community-based studies on treatment-seeking pathways to hospitals for severe disease would i

296 A bright and tumor-seeking donor-acceptor-donor (D-A-D) dye, IR-FD, is scre

297 ) ) limits, with and without shade- or water-seeking behaviours.

298 FO(GLUT)) restored cue-evoked food- or water-seeking, InsCtx ongoing activity continued to reflect ph

299 consumption without affecting food- or water-seeking.

300 ncrease in serum osmolality reinstates water-seeking behavior, demonstrating preservation of the phys