ライフサイエンスコーパス: 1,3-butadiene

1 soprene; 1,3-pentadiene; 1,4-pentadiene; and 1,3-butadiene).

2 nvestigated for the conversion of ethanol to 1,3-butadiene.

3 requires consideration of both conformers of 1,3-butadiene.

4 s to platform chemicals such as p-xylene and 1,3-butadiene.

5 eaction was well suited with a less-reactive 1,3-butadiene.

6 ance of the products was mainly ethylene and 1,3-butadiene.

7 ture a planar s-trans-conformation just like 1,3-butadiene.

8 ce exposed to a model DNA-damaging chemical, 1,3-butadiene.

9 radical or via cyano radicals reacting with 1,3-butadiene.

10 with classical double bonds of a 2,3-disila-1,3-butadiene.

11 7-99%) with no ene product from 2,3-dimethyl-1,3-butadiene.

12 ylation of terminal alkenes and 2,3-dimethyl-1,3-butadiene.

13 sence of a radical trap such as 2,3-dimethyl-1,3-butadiene.

14 putative ultimate carcinogenic metabolite of 1,3-butadiene.

15 hyde, trapped in 80% yield with 2,3-dimethyl-1,3-butadiene.

16 o-5-methoxybenzoquinone (14) and substituted 1,3-butadienes.

17 s an easy entry to the NHC-stabilized 1-bora-1,3-butadienes.

18 vailable and safe 4-alkoxycarbonyl-1,2-diaza-1,3-butadienes.

19 nes to afford predominantly (E,E)-1,4-diaryl-1,3-butadienes.

20 Dehydrohalogenation gives 2-alkyl-1,3-butadienes.

21 thesis was developed to generate (E)-1-cyano-1,3-butadiene (1) (10:1 E/Z) via tandem S(N)2 and E2' re

22 Diels-Alder cycloaddition of s-trans-1,3-butadiene (1) should yield trans-cyclohexene (7), ju

23 2' reactions leading to (E)- and (Z)-1-cyano-1,3-butadiene (1) were analyzed by density functional th

24 zyl radical, benzylallenyl radical, 1-phenyl-1,3-butadiene, 1,2-dihydronaphthalene, and naphthalene),

25 Exchange of toluene for anisole, 1,3-butadiene, 1,3-cyclohexadiene, thiophenes, pyrroles,

26 fferent organic pai systems (ethene, ethyne, 1,3-butadiene, 1,3-cyclopentadiene, furan, benzene) were

27 s for the isotopomeric species produced from 1,3-butadiene-1,1,4,4-d(4) dissociation.

28 tail, further studies were carried out using 1,3-butadiene-1,1,4,4-d(4).

29 der adducts of p-methoxycarbonylbenzyl trans-1,3-butadiene-1-carbamate and N,N-dimethylacrylamide hav

30 nthesized from (Z,Z)-1,4-bis(tert-butylthio)-1,3-butadiene (2) to evaluate the effects of electron-wi

31 yloxy-tert-butyldimethylsilane, (E)-1-phenyl-1,3-butadiene, 2,3-dihydrofuran, and 2,5-dihydrofuran) p

32 Z-1), 4-cyano-1,2-butadiene (2), and 2-cyano-1,3-butadiene (3).

33 benzyloxy-3Z,5E-hexadienoyl)- 1-aza-2-ethoxy-1,3-butadiene (40) undergoes cycloaddition to produce as

34 s, such as 1-methoxybutadiene (6g) and alkyl 1,3-butadienes (6a, 6j), the diamination is first-order

35 ) generated polymer-bound 2-(phenylsulfonyl)-1,3-butadiene (9) in situ which underwent Diels--Alder c

36 inal oxygen atoms stem from CO reacting with 1,3-butadiene, a C(2)H(2) reduction intermediate.

37 Reaction of 1 with 2,3-dimethyl-1,3-butadiene afforded the compound [Ar*GaCH(2)C(Me)C(Me

38 1,2-diazines; and 1,3,4-oxadiazoles), 1-aza-1,3-butadienes, alpha-pyrones, and cyclopropenone ketals

39 catalysts for the selective hydrogenation of 1,3-butadiene,, an industrially important reaction.

40 ween 2 equiv of (E,E)-1,4-bis(4-bromophenyl)-1,3-butadiene and 1,4-benzoquinone led to the formation

41 artially deuterated counterparts (1,1,4,4-D4-1,3-butadiene and 2,3-D2-1,3-butadiene) at two collision

42 ry studies of the photochemistry of 1-phenyl-1,3-butadiene and 4-phenyl-1-butyne.

43 -Alder cycloaddition, which occurs between a 1,3-butadiene and an alkene.

44 bonyls, and C1-C8 hydrocarbons (particularly 1,3-butadiene and benzene) were determined.

45 tly, a new reaction between 2-nitroperchloro-1,3-butadiene and electron-deficient anilines producing

46 Over 1000 transitions for s-trans-Z-1-cyano-1,3-butadiene and for syn-periplanar-4-cyano-1,2-butadie

47 Isoprene is the 2-methyl analog of 1,3-butadiene and is a possible human carcinogen (IARC G

48 rylhydrazine, starting from 2-nitroperchloro-1,3-butadiene and para-nitro aniline, and generated the

49 1,3-butadiene and styrene are main components of the car

50 der reactions of 1-methoxy-4-trimethylsiloxy-1,3-butadiene and the corresponding o-xylylene with acry

51 -consistent basis sets were applied to trans-1,3-butadiene and trans-isoprene as the smallest buildin

52 -consistent basis sets were applied to trans-1,3-butadiene and trans-isoprene as the smallest buildin

53 ted a(3)Pi(u) state have been conducted with 1,3-butadiene and two partially deuterated counterparts

54 s-Alder (DA) reactions of phosphaethene with 1,3-butadiene and with isoprene reveal asynchronous tran

55 The s-trans conformers of E-1-cyano-1,3-butadiene and Z-1-cyano-1,3-butadiene are observed,

56 es that were obtained from 2,3-disubstituted 1,3-butadienes and naphthoquinone followed by dehydrogen

57 omers (1,5-hexadiyne, fulvene, and 2-ethynyl-1,3-butadiene) and o-benzyne are detected, and their bra

58 aque development: the vapor phase component, 1,3 butadiene, and the tar component, the tobacco-specif

59 taminants such as benzene, nitrogen dioxide, 1,3-butadiene, and particulate matter.

60 toxins acrolein; acrylamide; acrylonitrile; 1,3-butadiene; and ethylene oxide) than combustible ciga

61 ers of E-1-cyano-1,3-butadiene and Z-1-cyano-1,3-butadiene are observed, while both the anti-clinal a

62 However, 1,3-butadienes are also formed in the case of ortho-subs

63 dienes, the 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes are still very reactive in Diels-Alder re

64 alkenes (ethylene, propylene, 1-butene, and 1,3-butadiene) are investigated by experiments and densi

65 The photodissociation dynamics of 1,3-butadiene at 193 nm have been investigated with phot

66 allyl cyanide, 1-octene, and trans-1-phenyl-1,3-butadiene at low temperatures and pressures with pas

67 erparts (1,1,4,4-D4-1,3-butadiene and 2,3-D2-1,3-butadiene) at two collision energies of 12.7 and 33.

68 k assessment due to inhalational exposure to 1,3-butadiene (BD) and styrene (ST) performed among work

69 1,3-Butadiene (BD) is an important industrial and enviro

70 1,3-Butadiene (BD) is an important industrial chemical a

71 P2 efficiently to 1,3-cyclohexadiene (CHD), 1,3-butadiene (BD), and (C2H4)Pt(PPh3)2 to form P2(CHD)2

72 -shift), closure to trialene (bicyclo[1.1.0]-1,3-butadiene), bond-shift isomerization to exchange C-2

73 omers of DEB are produced metabolically from 1,3-butadiene, but S,S-DEB is the most cytotoxic and gen

74 a reducing the ambient levels of benzene and 1,3-butadiene by 39.3-75.7 and 14-69.3%, respectively, a

75 should possess simultaneous high uptakes for 1,3-butadiene (C(4)H(6)) and n-butene (n-C(4)H(8)) count

76 e separation performance of the membrane for 1,3-butadiene (C(4)H(6)) from other C(4) hydrocarbons, w

77 on of the silicon nitride (SiN) radical with 1,3-butadiene (C(4)H(6)) via single collision conditions

78 system involving the cyano radical (CN) and 1,3-butadiene (C(4)H(6)), which predominantly yields an

79 exoergic reaction of the ethynyl radical and 1,3-butadiene, C(2)H + H(2)CCHCHCH(2) --> C(6)H(6) + H,

80 icon-bearing radical, silylidyne (SiH), with 1,3-butadiene (C4 H6 ) in the gas phase under single-col

81 is(2,6-dialkylphenyl)-1,4-diaza-2,3-dimethyl-1,3-butadiene) carrying nearly unperturbed nitric oxide

82 The abatement of 9 polychloro-1,3-butadienes (CBDs) in aqueous solution by ozone, UV-C

83 A 1,4-diamino-2,3-disila-1,3-butadiene derivative of composition (Me2-cAAC)2(Si2C

84 odular and atom-efficient synthesis of 2-aza-1,3-butadiene derivatives has been developed via nickel-

85 Polydienes, particularly 1,3-butadiene derivatives, are integral to the chemical

86 1G* of selected dilithium derivatives of the 1,3-butadiene dianion including cis-dilithio-1,4-bis(TMS

87 o)-1,1'-binaphtyl (BINAP) or 1,4-diphosphino-1,3-butadiene (dpb).

88 r reactions, somewhat more than 1,3-dialkoxy-1, 3-butadienes (e.g., Danishefsky's diene).

89 and isolated as pure compounds: (E)-1-cyano-1,3-butadiene (E-1), (Z)-1-cyano-1,3-butadiene (Z-1), 4-

90 mational equilibria of 10 methyl-substituted 1,3-butadienes [(E)- and (Z)-1,3-pentadiene; 2-methyl-1,

91 ienes [(E)- and (Z)-1,3-pentadiene; 2-methyl-1,3-butadiene; (E)-2-methyl-1,3-pentadiene; 2,3-dimethyl

92 e; (E)-2-methyl-1,3-pentadiene; 2,3-dimethyl-1,3-butadiene; (E,E)-, (E,Z)-, and (Z,Z)-2,4-hexadiene;

93 nd initiated by 1-ethoxy-1-(trimethylsiloxy)-1,3-butadiene (ETSB), our method enables rapid polymeriz

94 , isobutane, propylene, 2-methylpropene, and 1,3-butadiene even xenon are coencapsulated with other g

95 aptable to molecular epidemiology studies on 1,3-butadiene-exposed workers.

96 the radical to the diene moiety of 2-methyl-1,3-butadiene followed by extensive isomerization (hydro

97 esized by low-cost anionic polymerization of 1,3-butadiene followed by solution hydrogenation, restor

98 ed in mice treated with 3, 62.5, or 1250 ppm 1,3-butadiene for 10 days and rats exposed to 3 or 62.5

99 or 10 days and rats exposed to 3 or 62.5 ppm 1,3-butadiene for 10 days, or to 1000 ppm 1,3-butadiene

100 pm 1,3-butadiene for 10 days, or to 1000 ppm 1,3-butadiene for 90 days, using a newly developed immun

101 By contrast, Y-DeAlBEA was highly active for 1,3-butadiene formation but exhibited no activity for et

102 exhibited three phases of isoprene (2-methyl-1, 3-butadiene) formation, corresponding to (i) glucose

103 1-alkyl- or 1,3-dialkyl-substituted 1-boryl-1,3-butadienes forms secondary alkylboronates with excel

104 In this context, on-purpose production of 1,3-butadiene from biomass-derived feedstock is an inter

105 ission of the hydrocarbon isoprene (2-methyl-1,3-butadiene) from many C3 plants.

106 acetaldehyde and exhibited low activity for 1,3-butadiene generation.

107 cid ethyl ester with 2,3-bis(phenylsulfonyl)-1,3-butadiene gives rise to a 7-oxa-1-azanorbornane cycl

108 2-Dimethylphenylsilyl-1,3-butadiene has also been prepared from chloroprene on

109 1.0]but-2-ylmethanols (endo- and exo-9) from 1,3-butadiene has been developed.

110 2-Triethoxysilyl-substituted 1,3-butadiene has been prepared in 30-g quantities from

111 ried out in a 4.4 M solution of 2,3-dimethyl-1,3-butadiene in CH2Cl2.

112 luded; experiments with partially deuterated 1,3-butadiene indicate the formation of the thermodynami

113 ice, a strain that acquired higher levels of 1,3-butadiene-induced DNA damage, around the same genes,

114 AST/EiJ mice, which acquired relatively less 1,3-butadiene-induced DNA damage, we observed increased

115 1,3-Butadiene is an important industrial chemical used i

116 droxyflavones with trans, trans-1,4-diphenyl-1,3-butadiene is described.

117 antioselective carboboration of 1,1-bisboryl-1,3-butadiene is developed to generate enantioenriched 3

118 The dehydration of crotyl alcohol to 1,3-butadiene is facile and occurs over the mildly Brons

119 surement of styrene, ethylene, 1-octene, and 1,3-butadiene is illustrated.

120 1,3-Butadiene is metabolized to several epoxides that fo

121 Together, these data show that 1,3-butadiene is primarily metabolized via the 3-butene-

122 ontrast, hole upconversion in C2-substituted 1,3-butadienes is activated by acceptors with the oxidat

123 A two-step procedure for preparing 2-alkyl-1,3-butadienes is described.

124 ric Diels-Alder reaction of N-sulfonyl-1-aza-1,3-butadienes is reported enlisting a series of 19 enol

125 Isoprene (2-methyl-1,3-butadiene) is emitted to the atmosphere each year in

126 oaches to purify commodity chemicals such as 1,3-butadiene, isobutene, and 1-butene, but the very sim

127 Approximately 500 Tg of 2-methyl-1,3-butadiene (isoprene) is emitted by deciduous trees e

128 ynyl (methylethynyl, CH(3) CC) with 2-methyl-1,3-butadiene (isoprene, C(5) H(8) ).

129 (X(1) Sigmag (+) , a(3) Piu ), with 2-methyl-1,3-butadiene (isoprene; C5 H8 ; X(1) A') accessing the

130 present in cigarette smoke (e.g., acrolein, 1,3-butadiene, isoprene, acrylamide, benzene, and toluen

131 ght into species and exposure differences in 1,3-butadiene metabolism.

132 The analyses of several adducts derived from 1,3-butadiene metabolites provided new insight into spec

133 ining N(2)-guanine adducts of stereoisomeric 1,3-butadiene metabolites.

134 lene/ethylene, propyne/propylene, and butyne/1,3-butadiene mixtures, with unprecedented dynamic separ

135 he carbon-carbon double bond of the 2-methyl-1,3-butadiene molecule.

136 actions of ethynyl radicals with substituted 1,3-butadiene molecules.

137 Although neither s-trans-E-1-cyano-1,3-butadiene nor anti-clinal-4-cyano-1,2-butadiene can

138 ed through reaction of pyridyl radicals with 1,3-butadiene or sequentially with two acetylene molecul

139 for both the direct conversion of ethanol to 1,3-butadiene or the formation of this product by the re

140 odds ratio (OR) = 2.30; 95% CI: 1.44, 3.67], 1,3-butadiene (OR = 2.23; 95% CI: 1.28, 3.88), benzene,

141 lorobenzene (OR = 3.27; 95% CI: 1.17, 9.14), 1,3-butadiene (OR = 3.15; 95% CI: 1.57, 6.32), and benze

142 monitoring data, concentrations of benzene, 1,3-butadiene, perchloroethylene, and hexavalent chromiu

143 .2.2]octa-2,5-diene, and benzobarrelene with 1,3-butadienes proceed in excellent yields using cobalt-

144 ability of the substituent to stabilize the 1,3-butadiene radical cation by electron donation or con

145 of the (E) and (Z) isomers of the resulting 1,3-butadiene radical cations depends largely on steric

146 lecules (C(2)) with C(4)H(6) isomers such as 1,3-butadiene represent a potential, but hitherto unnoti

147 10 with cyclohexa-1,3-diene and 2,3-dimethyl-1,3-butadiene (several cycloadducts characterized by X-r

148 For example, donors at C1 in 1,3-butadiene shift the reaction to the hole-upconverted

149 Allenyl carbonate was used as a 1,3-butadiene surrogate to develop a photocatalytically

150 arbon atoms are attached to C2 and C3 of the 1,3-butadiene tether.

151 is(pentafluorophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene; TFA = trifluoroacetate] has been reported

152 is(pentafluorophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadiene; TFA is trifluoroacetate] converts benzene

153 arbon to one of the terminal carbon atoms of 1,3-butadiene, the collision complex undergoes trans-cis

154 d to the reaction of 1,1-difluoroallene with 1,3-butadiene, the results of which indicate that the us

155 For trans-1-phenyl-1,3-butadiene, the stable alkyl complex is an eta(3)-all

156 To specifically examine metabolism of 1,3-butadiene to 1,2;3,4-diepoxybutane, the formation of

157 d 1,4-addition across the commodity chemical 1,3-butadiene to afford skipped polyene products is repo

158 combination of H2C horizontal lineNH and cis-1,3-butadiene to form a six-membered ring was examined b

159 o proceed efficiently from 1 to 2,3-dimethyl-1,3-butadiene to form Diels-Alder product 3 with a zero-

160 lcohols with methylallene (1,2-butadiene) or 1,3-butadiene to form products of anti-crotylation with

161 e (9) regioselectively reacts with 1-methoxy-1,3-butadiene to provide cycloadduct 16.

162 ibe a [2+2] cycloaddition/oligomerization of 1,3-butadiene to yield a previously unrealized telecheli

163 tion of 1,4-, 1,3-, and 2,3-bis(2-nitroaryl)-1,3-butadienes to afford 2,2'-, 2,3'-, and 3,3'-biindole

164 eaves of many plants emit isoprene (2-methyl-1,3-butadiene) to the atmosphere, a process which has im

165 nyl]benzenes were prepared from 2,3-dimethyl-1,3-butadiene using Diels-Alder cycloadditions and Pd(0)

166 ominantly yields an acyclic product (1-cyano-1,3-butadiene) via a simple addition-elimination pathway

167 ldehydes and ketones, furans, acrylonitrile, 1,3-butadiene, vinyl chloride, and nitromethane) in the

168 Additionally, 1,3-dipyrrolidino-1,3-butadiene was shown to be significantly more reactiv

169 Acrolein, furan, acrylonitrile, and 1,3-butadiene were considered to be the most harmful VOC

170 ative syntheses of several 2,3-disubstituted 1,3-butadienes were achieved.

171 l group nonbonded interactions in conjugated 1,3-butadienes were delineated.

172 and chiral 1-(2-oxazolidinon-3-yl)-3-siloxy-1,3-butadienes were prepared from readily available star

173 was similar in mice exposed to 3 or 62.5 ppm 1,3-butadiene, whereas 2-hydroxy-3-butenyl-valine was 3-

174 selective, while 1-methoxy-4-trimethylsiloxy-1,3-butadiene will give a small preference ( approximate

175 in solution in the presence of 2,3-dimethyl-1,3-butadiene with a quantum efficiency of approximately

176 For the reaction of 2,3-dimethyl-1,3-butadiene with acrylonitrile, the concerted reaction

177 lar cycloaddition of 2,3-bis(phenylsulfonyl)-1,3-butadiene with an appropriate oxime.

178 s a solid catalyst for the polymerization of 1,3-butadiene with high stereoselectivity (>99% 1,4-cis)

179 the volatile hydrocarbon isoprene (2-methyl-1,3-butadiene), with subsequent analysis of isoprene by

180 4-decylaniline and the volatile 2,3-dimethyl-1,3-butadiene, with an outlier being operationally defin

181 (E)-1-cyano-1,3-butadiene (E-1), (Z)-1-cyano-1,3-butadiene (Z-1), 4-cyano-1,2-butadiene (2), and 2-cy