ライフサイエンスコーパス: 1-butanol

1 ty under high submicellar conditions (10-25% 1-butanol).

2 y and the inhibition of the Shaw2 channel by 1-butanol.

3 S4-S5 linkers conferred weak potentiation by 1-butanol.

4 ed by genistein, PD98059, and PLD-inhibitor, 1-butanol.

5 butane oxidation capability and accumulated 1-butanol.

6 inactivated was unable to grow on butane or 1-butanol.

7 y be more important in the detoxification of 1-butanol.

8 d the excess hydrogen-bond acceptor sites of 1-butanol.

9 well as leucine analogues, such as 3-methyl-1-butanol.

10 and elution with a 2:1 mixture of 1-propanol:1-butanol.

11 ediated signaling, 2,3-diphosphoglycerate or 1-butanol.

12 ethyl-2-buten-1-ol, and 300 mg/L of 3-methyl-1-butanol.

13 uction to 3-methyl-2-buten-1-ol and 3-methyl-1-butanol.

14 tectable 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

15 13)C,(1)H] correlations in the test molecule 1-butanol.

16 timulated ERK activity was also inhibited by 1-butanol.

17 However, they show increased resistance to 1-butanol.

18 atment of neutrophils with ethanol (0.8%) or 1-butanol (0.3%), which results in the accumulation of p

19 Application of 1-butanol (1-buOH), a selective inhibitor of PtdOH produ

20 4-nonadienal, (E,E)-2,4-decadienal, 3-methyl-1-butanol, 1-hexanol, and 2-pentyl-furan, were employed

21 ic compounds identified in this study, e.g., 1-butanol, 1-octen-3-ol, 2-and 3-methyl butanoic acid, h

22 Hexanal, 3-methyl-1-butanol, 1-pentanol, 1-octen-3-ol, acetic acid, furfur

23 ence of a vertical concentration gradient as 1-butanol/1-hexanol droplets evaporate.

24 asure concentration gradients in evaporating 1-butanol/1-hexanol droplets on a hydrophobic surface.

25 s and higher alcohol esters, namely 3-methyl-1-butanol, 2,3-butanediol, ethyl lactate, 3-methyl-1-but

26 rotein interactions and low levels of fruity 1-butanol, 2-methyl-, acetate.

27 roduce higher alcohols including isobutanol, 1-butanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-

28 of yeast promoted the formation of 3-methyl-1-butanol, 2-methyl-1-propanol and 3-(methylsulfanyl)-pr

29 d acetic acid, followed by hexanol, 3-methyl-1-butanol, 2-phenylethanol, 3-methylbutanal, hexanal, be

30 etate, isoamyl acetate, isobutanol, 2-methyl-1-butanol, 2-phenylethanol, E-2-hexenol, octanal, nonana

31 en the PLS analysis were evaluated, 3-methyl-1-butanol, 2-phenylethyl alcohol, nonanal, and benzaldeh

32 oline/1-octen-3-ol, for Venere, and 3-methyl-1-butanol/2-methyl-1-butanol, for Apollo, were also foun

33 variations during smoking, of which 3-methyl-1-butanol, 3,7-dimethyl-1,3,6-octatriene, hydroxy butano

34 ls including isobutanol, 1-butanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from g

35 aining emulsions had high levels of 2-methyl-1-butanol, 3-methyl-1-butanol, and 2-butanone after stor

36 sional spectra were acquired from samples of 1-butanol (55 nmol) and ethylbenzene (250 nmol).

37 ed urine 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol (a biomarker of cigarette smoke exposure) on

38 ry vesicles from the TGN was sensitive to 1% 1-butanol, a concentration that inhibited PLD-catalyzed

39 of BOH and BDH at three different levels of 1-butanol, a nontoxic level (0.1 mM), a growth-supportin

40 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol, a validated tobacco-specific marker, was meas

41 presented the highest contents of 3/2-methyl-1-butanol, acetoin and organic acids.

42 known negative regulators of ABA signaling: 1-butanol, an inhibitor of phospholipase D, and abi1-1,

43 its activation by electron transfer to yield 1-butanol and (n-Bu3Sn)2O.

44 -azioctanol, the photoactivatable analogs of 1-butanol and 1-octanol, to photolabel the purified Ig1-

45 o our results, dimethyl disulphide, 3-methyl-1-butanol and 1-octen-3-one odorants showed the highest

46 hol inhibition of WT-L1 adhesion was between 1-butanol and 1-pentanol.

47 PLD inhibitors 1-butanol and 2, 3-diphosphoglycerate, or the ARF6(N48R)

48 ethyl acetate, 2-methyl-1-propanol, 3-methyl-1-butanol and 2-methyl-1-butanol and furan derivatives l

49 ethyl acetate, 2-methyl-1-propanol, 3-methyl-1-butanol and 2-methyl-1-butanol was determined by means

50 nol, 1-butanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from glucose, a renewable

51 e exception of 2-methyl-1-propanol, 3-methyl-1-butanol and 2-phenylethyl alcohol, which decreased 68%

52 Inhibitors of phospholipase D (1-butanol and a dominant negative construct) prevented t

53 C4 column and were eluted with a mixture of 1-butanol and acetic acid.

54 d higher levels of 2-phenylethanol, 3-methyl-1-butanol and diethyl succinate, and lower concentration

55 1-propanol, 2-methyl-1-propanol, 3/2-methyl-1-butanol and ethyl octanoate were evaporated whereas th

56 These aroma compounds were 3-methyl-1-butanol and eugenol, phenethyl alcohol, 2-phenethyl ac

57 -1-propanol, 3-methyl-1-butanol and 2-methyl-1-butanol and furan derivatives like 5-(hydroxymethyl)-2

58 on the inhibition of the K-Shaw2 channel by 1-butanol and halothane.

59 uptake; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides (total NNAL), a biomarker

60 well as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides (total NNAL), and cotinin

61 For 1-butanol and nonane, kappa decreases with increasing pr

62 tions, we used a mixture of Triton X-100 and 1-butanol and observed that water-soluble natural and sy

63 y 56% and 44% conversions were achieved when 1-butanol and octadecanol were employed, respectively.

64 exanal concentration was higher and 2-methyl-1-butanol and toluene lower for C and GSC than for GSPC.

65 tes included n-pentane, n-hexane, n-heptane, 1 -butanol, and 1-pentanol.

66 he homologous series of 1-alkanols (ethanol, 1-butanol, and 1-hexanol) with Shaw2 K(+) channels in Xe

67 ation of four alcohols (ethanol, 1-propanol, 1-butanol, and 1-pentanol) to the corresponding carboxyl

68 high levels of 2-methyl-1-butanol, 3-methyl-1-butanol, and 2-butanone after storage.

69 ella, Lachnospiraceae, 4-methyl-2-pentanone, 1-butanol, and 2-butanone could discriminate NAFLD patie

70 effects for n-pentane, n-hexane, n-heptane, 1-butanol, and benzene solutes at infinite dilution.

71 aPKCs were inhibited by genistein, PD98059, 1-butanol, and expression of dominant-negative forms of

72 e, urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and hair and nail nicotine levels were measur

73 enyl)-7H-pyrrolo[2,3-d]pyrimidin-4-y l]amino-1-butanol, and NBI-27914 at doses (30 mg/kg, i.p.) that

74 mmunoglobulin G, and apoferritin with water, 1-butanol, and nonane.

75 The substrate activation with ethanol and 1-butanol are explained by an ordered mechanism with an

76 that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need

77 for oxidation of ethanol, cyclohexanol, and 1-butanol are quantitatively explained with the abortive

78 Commercial availability of (S)-2-methyl-1-butanol as a relatively inexpensive material suggested

79 Interestingly, replacing n-heptane with 1-butanol as a solvent led to a reactivity decrease of s

80 otope effect was determined to be 0.67 using 1-butanol as the substrate.

81 nickel to generate a catalyst that generates 1-butanol at unprecedented faradaic efficiencies (xi = 4

82 bly, rat NRK and GH3 cells were treated with 1-butanol, BFA, or nocodazole.

83 ol (MeOH), ethanol (EtOH), 2-propanol (IPA), 1-butanol (BuOH), acetonitrile (ACN) and the solvent mix

84 that increasing concentrations of ethanol or 1-butanol but not 2-butanol (0.05-0.5%) inhibited fMLP-i

85 e mutant of PLD1 or by the presence of 50 mM 1-butanol but not tert-butanol, an indication that these

86 O(2) and 5% CO(2)) in the presence of 0.05% 1-butanol, but not tertiary-butanol, stimulated PLD as e

87 Although production of 1-butanol by the fermentative coenzyme A (CoA)-dependent

88 ersion of the product of the PLD reaction by 1-butanol caused a partial loss of the [3H]thymidine res

89 were inhibited by genistein, PD98059, UO126, 1-butanol, cell-permeable myristoylated PKC-zeta pseudos

90 l, trans-2-hexenal) and alcohols (1-hexanol, 1-butanol, cis-3-hexenol) and had significant discrimina

91 During washout of 1-butanol, clathrin, a ubiquitous coat protein implicate

92 reover, the pretreatment of neutrophils with 1-butanol decreased Fgr activity in cells stimulated wit

93 Conversely, inhibition of PLD1 activity by 1-butanol decreases betaAPP trafficking in both wt and P

94 alkanols, the step that limits 2-butanol and 1-butanol dehydration rates; the latter two reactions sh

95 a grown on butane or 1-butanol expresses two 1-butanol dehydrogenases, a quinoprotein (BOH) and a qui

96 ol/vol) O(2), CuSO(4) (0.5 microM) repressed 1-butanol-dependent induction of beta-galactosidase acti

97 the mineral salts of standard growth medium, 1-butanol-dependent induction was significantly represse

98 kers showed that the potentiation induced by 1-butanol depends on the combination of a single mutatio

99 A structural analog of choline, 3,3-dimethyl-1-butanol (DMB), is shown to non-lethally inhibit TMA fo

100 risk, and can be suppressed by 3,3-dimethyl-1-butanol (DMB).

101 pressed by supplementation with 3,3-dimethyl-1-butanol (DMB).

102 However, 1-butanol does not always effectively reduce PA accumula

103 Inhibition of PLD activity by 0.1% 1-butanol during the initial 20 min of ABA treatment res

104 e solvent environment most closely resembles 1-butanol (epsilon = 17), although the energetic contrib

105 responses of Escherichia coli (DH5alpha) to 1-butanol exposure (1.2% [vol/vol]).

106 typic responses of E. coli to 1.2% (vol/vol) 1-butanol exposure included the following: (i) decreased

107 Pseudomonas butanovora grown on butane or 1-butanol expresses two 1-butanol dehydrogenases, a quin

108 1-Butanol extraction of chicken egg yolk homogenates con

109 y in organic solvents, ImmE1 was purified by 1-butanol extraction of isolated membranes, followed by

110 for Venere, and 3-methyl-1-butanol/2-methyl-1-butanol, for Apollo, were also found to act as ageing

111 time the direct photosynthetic production of 1-butanol from cyanobacteria Synechococcus elongatus PCC

112 bol-13-acetate-stimulated IL-8 production by 1-butanol further strengthened this observation.

113 d methyl heptenone) and four minor (3-methyl-1-butanol, gamma-hexalactone, 2-nonanone, and dodecanoic

114 1-Butanol had no effect on Cch-stimulated Pyk2, Ras, and

115 okers by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol had similar severity of lung injury as patient

116 nd urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol identified 27 of the 28 nonsmokers by history

117 nd urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol identified considerably more active smokers th

118 sing 100 mM sodium dodecyl sulfate (SDS) and 1-butanol in 10 mM sodium-phosphate (pH 7.2) at a flow r

119 opha H16, to produce isobutanol and 3-methyl-1-butanol in an electro-bioreactor using CO(2) as the so

120 from readily available aldehydes and 4-nitro-1-butanol in three steps.

121 Since 4-nitro-1-butanol in turn is prepared in two steps via Michael a

122 l compound using an alcohol (e.g., methanol, 1-butanol) in the presence of a relatively strong Lewis

123 1-Butanol increased Cch-stimulated protein secretion and

124 ications to the 2- and 3-carbon positions of 1-butanol increased potency, whereas modifications that

125 tion coefficients; e.g., the Kovats index of 1-butanol increases by more than 150 Kovats units.

126 le, brefeldin A (BFA), and primary alcohols (1-butanol) induce reversible fragmentation of the Golgi

127 alactosidase activity, was used to show that 1-butanol induced the BMO promoter in the presence or ab

128 Ethanol and 1-butanol inhibit L1-mediated cell-cell adhesion (L1 adh

129 1-Alcohols from methanol through 1-butanol inhibit with increasing potency the cell-cell

130 A screen for 1-butanol-insensitive mutants identified additional prot

131 butol [Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol] is used to treat tuberculosis as well as diss

132 plets made of cetyltrimethylammonium bromide/1-butanol/isooctane.

133 tyrate and ethyl 2-methylbutyrate), 3-methyl-1-butanol, isopropyl acetate, and finally the two sulfid

134 on PKC translocation and degranulation, and 1-butanol itself had no effect on PKC translocation when

135 BOH exhibited high affinity towards 1-butanol (K(m) = 1.7 +/- 0.2 microM).

136 nts with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels consistent with active smoking and was

137 nts with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels in the active smoking range were younge

138 Urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels were consistent with active smoking in

139 tectable 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels.

140 otonated monomers and proton-bound dimers of 1-butanol, limits of detection of 1.9 ppt(v) and 110 ppt

141 (Z)-3-hexen-1-ol, 3-methyl-1-butanol, linalool, citronellol, and geraniol presented

142 to the surface properties of neat water and 1-butanol liquids.

143 ng catalyst system toward chemically similar 1-butanol makes it possible to synthesize the competent

144 r under micellar conditions using 1-2% (v/v) 1-butanol mobile phase to remove plasma proteins and con

145 ordination environment upon interaction with 1-butanol molecules, which after a thermal treatment abo

146 ributions suggests that the formation of the 1-butanol monolayer is driven by an excellent match betw

147 A dense 1-butanol monolayer is observed at the surface of the wa

148 g/L) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) (0.2 ng/L) along with the reduction of

149 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides (sum of which is d

150 smoking: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its O-glucuronide, 4-[(methylnitros

151 NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) as the targets, we first developed a so

152 tabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine is frequently used as a biomar

153 rosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is present in the urine of tobacco user

154 ine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a metabolite of the powerful lung carc

155 ng total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a tobacco-specific carcinogen.

156 abolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), is an important mechanism for 4-(methy

157 ry total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), N'-nitrosonornicotine (NNN), and cotin

158 NK), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), NNAL-N-beta-glucuronide, and NNAL-O-be

159 abolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), was sequestered in the lung.

160 product 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), which, in turn, can be glucuronidated,

161 urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

162 urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

163 omarker [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)], an established biomarker (cotinine),

164 tabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [NNAL]) and VOCs (including metabolites of the

165 osamine (4-[methylnitrosamino]-1-[3-pyridyl]-1-butanol [NNAL]) in addition to clinical history.

166 ncluding 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol [NNAL]), metals, polycyclic aromatic hydrocarb

167 The effects of ethanol and 1-butanol on cell-cell adhesion were antagonized by 1-pe

168 products due to the strong chemisorption of 1-butanol onto the Bronsted acid sites.

169 cal content of ImmE1 is approximately 80% in 1-butanol or 2,2,2-trifluoroethanol, consistent with a p

170 rgin whether PLD function was disrupted with 1-butanol or the small inhibitory RNAs.

171 NZVI (RL-Pd-NZVI) when reacted with TCE in a 1-butanol organic phase with limited amounts of water re

172 d BDH mRNAs were induced whenever the cell's 1-butanol oxidation activity was induced.

173 odel is proposed in which the electrons from 1-butanol oxidation follow a branched electron transport

174 ion of 1-hexanol production by extending the 1-butanol pathway provides the possibility to produce ot

175 holipase D (PLD) activity, the PLD inhibitor 1-butanol prevented the unsaturated fatty acid-induced r

176 ndent alcohol dehydrogenase (YqhD) increased 1-butanol production by 4-fold.

177 fficiency occurs at -1.48 V vs Ag/AgCl, with 1-butanol production commencing at an overpotential of 3

178 atio of the rates of 2-butanol production to 1-butanol production compared to Rev WT.

179 ed upon exposure of the calcined material to 1-butanol, providing stability against water and, most i

180 alyst for the Guerbet reaction of ethanol to 1-butanol, providing turnover numbers up to 725 000 Ru(-

181 ation of Maillard reaction products 3-methyl-1-butanol, pyrazine, 2-ethylpyrazine, 2-ethyl-3-methylpy

182 us failed to reform efficiently after BFA or 1-butanol removal.

183 regulation of phosphoinositide production by 1-butanol resulted in diminished PIP(2) in the plasma me

184 D-mediated PA synthesis, by incubation with 1-butanol, resulted in the complete fragmentation of the

185 wth hormone and prolactin, were treated with 1-butanol resulting in the synthesis of phosphatidylbuta

186 h 0.4M perchloric acid and purification with 1-butanol significantly shortened sample preparation (30

187 iquid interfaces of mutually saturated water/1-butanol solutions at a temperature of 298.15 K were in

188 everal alcohols, notably isoamyl alcohol and 1-butanol, stimulate filamentous growth in haploid cells

189 by extending the coenzyme A (CoA)-dependent 1-butanol synthesis reaction sequence catalyzed by exoge

190 . butanovora could tolerate higher levels of 1-butanol than the P. butanovora boh::tet strain and the

191 Most significantly, in the presence of 1-butanol the architecture of the Golgi apparatus was di

192 en-1-ol, 3-methyl-2-buten-1-ol, and 3-methyl-1-butanol, three C5 alcohols that serve as potential bio

193 to Ala-33, increased the alcohol cutoff from 1-butanol to 1-decanol.

194 expressing wild-type Arf6 by treatment with 1-butanol to inhibit the formation of phosphatidic acid

195 ce of nucleophilic and biomimetic substrates 1-butanol, tosylhydrazine, or tetrahydrofurfuryl alcohol

196 nalytical methodologies were applied to both 1-butanol-treated and control cells to draw correlations

197 -opening of chiral trans-stilbene oxide with 1-butanol used as a test reaction.

198 ) system, where neither 3-hydroxybutanal nor 1-butanol was detected.

199 -1-propanol, 3-methyl-1-butanol and 2-methyl-1-butanol was determined by means of head space solid ph

200 story or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol was not associated with acute respiratory dist

201 by urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol was significantly associated with acute respir

202 3-Methyl-1-butanol was the major compound identified in the ferme

203 Instead, upon 1-butanol washout, it maintained a compact, tight morpho

204 tanoate, whereas phenyl ethanol and 3-methyl-1-butanol were dominating alcohols.

205 the TSNA 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol were identified and quantified in authentic dr

206 anone, 2-pentanone, 2-heptanone and 3-methyl-1-butanol were identified as relevant VOCs for Lactobaci

207 anone, 2-pentanone, 2-heptanone and 3-methyl-1-butanol were identified as relevant VOCs for Lactobaci

208 2-Butanone and 3-methyl-1-butanol were identified in Lactococcus lactis subsp. l

209 2-Butanone and 3-methyl-1-butanol were identified in Lactococcus lactis subsp. l

210 L [urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol] were measured to categorize smoking status.

211 Beas-2B exposure to 1-butanol, which converts the PLD-generated phosphatidic

212 Incubating embryos with 1-butanol, which diverts production of phosphatidic acid

213 on of PA is inhibited by the primary alcohol 1-butanol, which has thus been widely employed to identi

214 broblasts deficient in PLD activity and also 1-butanol, which inhibits phosphatidic acid production b

215 resistant membrane fractions is inhibited by 1-butanol, which subverts production of phosphatidic aci

216 sporulation, because treatment of cells with 1-butanol, which supports Spo14p-catalyzed PtdCho breakd

217 edium in the presence of different levels of 1-butanol, wild-type P. butanovora could tolerate higher

218 o synthesize the competent Guerbet substrate 1-butanol with >99% selectivity.

219 his is the first electrocatalyst to generate 1-butanol with high faradaic efficiency.

220 An abrupt cutoff exists after 1-butanol, with 1-pentanol and higher 1-alcohols showing

221 ten from flour defatted with water-saturated 1-butanol (WSB; extracted at 20 degrees C) and 2-propano

222 ith adenoviruses overnight or the inhibitors 1-butanol, Y-27632, or C3 exotoxin before stimulation wi