ライフサイエンスコーパス: 2,2,2-trifluoroethanol

1 lyte trimethylamine N-oxide or the cosolvent 2,2,2-trifluoroethanol.

2 lvents acetonitrile, dimethyl sulfoxide, and 2,2,2-trifluoroethanol.

3 hanol, and a 1:1 (v/v) mixture of CH2Cl2 and 2,2,2-trifluoroethanol.

4 the corresponding imidazolium salts in basic 2,2,2-trifluoroethanol.

5 dichroic spectra obtained in the presence of 2,2,2-trifluoroethanol.

6 E = 1.8), 2-propanol (28 ps, KIE = 1.4), and 2,2,2-trifluoroethanol (4.4 ps, KIE = 3.2), which indica

7 8-65% in aqueous solutions containing 40-80% 2,2,2-trifluoroethanol, a lipomimetic solvent, and was m

8 ing folding, was dramatically accelerated by 2,2,2-trifluoroethanol, a solvent that stabilizes alpha-

9 High concentrations (>50%, v/v) of 2,2,2-trifluoroethanol also dissociate TTR(10-19) fibril

10 re analyzed by circular dichroism in aqueous 2,2,2-trifluoroethanol and in buffered aqueous solutions

11 nthetic channel proteins were transferred to 2,2,2-trifluoroethanol and reconstituted into vesicle me

12 pha-helices in the lower dielectric solvents 2,2,2-trifluoroethanol, and a 1:1 (v/v) mixture of CH2Cl

13 The method was validated with 2,2,2-trifluoroethanol, and applied to analyze heptafluo

14 ile and in acetonitrile solutions containing 2,2,2-trifluoroethanol, and several Arrhenius functions

15 In particular, additions of 2,2,2-trifluoroethanol as a hydrogen bond donor in solut

16 ng ammonia as the amine component, employing 2,2,2-trifluoroethanol as a non-nucleophilic solvent in

17 ) had an alpha-helix content of 100% in 100% 2, 2,2-trifluoroethanol at 0 degrees C.

18 ies of peptides from TFE/H2O mixtures (TFE = 2,2, 2-trifluoroethanol) back to water, the thermal unfo

19 f ImmE1 is approximately 80% in 1-butanol or 2,2,2-trifluoroethanol, consistent with a previous membr

20 oved by omission of the four data points for 2,2,2-trifluoroethanol-ethanol mixtures (F-test value fr

21 Two modifiers (2,2,2-trifluoroethanol, formaldehyde) that produce anion

22 6]) > 2,2-dichloro- > 2-chloro approximately 2,2,2-trifluoroethanol > ethanol.

23 2,2,2-Trifluoroethanol increased response of more hydrop

24 )3, prepared from readily available B2O3 and 2,2,2-trifluoroethanol, is as an effective reagent for t

25 detected by laser flash photolysis (LFP) in 2,2,2-trifluoroethanol (lambda = 580 nm, tau = 690 +/- 1

26 l chloride (2) in aqueous methanol, ethanol, 2,2,2-trifluoroethanol, n-propyl alcohol, isopropyl alco

27 anol-O-d (26 ps), 2-propanol-OD (40 ps), and 2,2,2-trifluoroethanol-O-d (14 ps) are longer than those

28 n donors (methanol, 2-methyl-2-propanol, and 2,2,2-trifluoroethanol) on SmI2-initiated 5-exo-trig ket

29 h NAD(+) and unreactive substrate analogues, 2,2,2-trifluoroethanol or 2,3,4,5,6-pentafluorobenzyl al

30 egions that promote aggregation in 25% (v/v) 2,2,2 trifluoroethanol (TFE) are different from those th

31 re, these active samples were incubated with 2,2,2,-trifluoroethanol (TFE), a product analog that ser

32 ubstrate, and this is facilitated by solvent 2,2,2-trifluoroethanol (TFE) acting as a proton shuttle.

33 The first method uses 2,2,2-trifluoroethanol (TFE) and a large excess of amine

34 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) and 2,2,2-trifluoroethanol (TFE) as reaction media is descri

35 Here we show that low concentrations of 2,2,2-trifluoroethanol (TFE) convert predominately unstr

36 ) (PCL) and poly(vinyl pyrrolidone) (PVP) in 2,2,2-trifluoroethanol (TFE) for the generation of PVP/T

37 ed state of hen lysozyme formed in 60% (v/v) 2,2,2-trifluoroethanol (TFE) has been studied using hydr

38 ted proteins in aqueous solutions containing 2,2,2-trifluoroethanol (TFE) have shown that the formati

39 2,2,2-Trifluoroethanol (TFE) is known to stabilize pepti

40 2,2,2-Trifluoroethanol (TFE) is widely used to induce he

41 2,2,2-Trifluoroethanol (TFE) most stabilizes the alpha-h

42 accomplished with Dowex 1 x 2 (CF3CH2O-) in 2,2,2-trifluoroethanol (TFE) or lithium trifluoroethoxid

43 )N-HSQC spectra of IA(3) in water and in 23% 2,2,2-trifluoroethanol (TFE) shows that the individual r

44 s been investigated in aqueous buffer and in 2,2,2-trifluoroethanol (TFE) using CD and NMR spectrosco

45 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) and 2,2,2-trifluoroethanol (TFE) using different manganese c

46 ts a helical conformation in the presence of 2,2,2-trifluoroethanol (TFE), a solvent known to stabili

47 s of helix-stabilizing cosolvents, including 2,2,2-trifluoroethanol (TFE), on the thermodynamics and

48 intermediate (10-20% v/v) concentrations of 2,2,2-trifluoroethanol (TFE).

49 sidues 4-14; and helix 2, residues 20-29) in 2,2,2-trifluoroethanol (TFE).

50 se in k(d) from tert-butylbenzene (tBuPh) to 2,2,2-trifluoroethanol (TFE).

51 ies were recorded in the solvent system (40% 2,2,2-Trifluoroethanol (TFE)/water), which gave the larg

52 re reported for solvolyses in acetone/water, 2,2,2-trifluoroethanol(TFE)/water, and TFE/ethanol mixtu

53 as decreased markedly in the presence of 50% 2,2,2-trifluoroethanol, which causes loss of tertiary st