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1 to zanamivir (3-7-fold increase in IC(50) or 50% effective concentration).
3 ncephalographic effect, 12.7% over baseline; 50% effective concentration, 13.1 ng/mL; and effect-site
5 tant over 12 weeks and exceeded the in vitro 50% effective concentration by 5000-fold in vaginal flui
6 sed a dose-dependent reduction in VZV yield (50% effective concentration, congruent with 8 microM).
7 ntified by population sequencing, the median 50% effective concentration (EC(50) ) values for BMS-790
9 ivity under posttreatment conditions [median 50% effective concentration (EC(50)) = 3.80 nM to 1.73 m
10 V mutation showed a 2.9-fold increase in the 50% effective concentration (EC(50)) for adefovir compar
11 rations approximately 100-fold the antiviral 50% effective concentration (EC(50)) for genotype 1 viru
13 efficiently neutralized LT in vitro, with a 50% effective concentration (EC(50)) of 0.1 nM, and prov
14 Remdesivir inhibited Ituri Ebola virus at a 50% effective concentration (EC(50)) of 12nM (with a sel
16 locks astrovirus replication in vitro with a 50% effective concentration (EC(50)) of approximately 1.
17 The most active compound, VF-57a, displays a 50% effective concentration (EC(50)) of ~0.8 muM and an
18 cells and cell culture infectious virus with 50% effective concentrations (EC(50)s) of 46.8 and 16.1
19 inhibits both murine hepatitis virus (MHV) (50% effective concentration [EC(50)] = 0.17 muM) and Mid
20 ily induce the dimerization of Tp34; Cu(2+) (50% effective concentration [EC(50)] = 1.7 muM) and Zn(2
21 activities and reduces HBsAg both in vitro (50% effective concentration [EC(50)] ranged from 1.4 to
22 However, the median effective concentration (50% effective concentration, EC(50)) of ropivacaine requ
23 ll activation, causing a 66% decrease in the 50% effective concentration (EC50) for activation throug
24 were effectively neutralized by 81.39a at a 50% effective concentration (EC50) of <0.01 to 4.9 mug/m
25 tate mRNA and JNK1 protein expression with a 50% effective concentration (EC50) of <0.1 microM but di
26 ecting several noxious stimuli, exhibiting a 50% effective concentration (EC50) of 12.6 +/- 3.2 muM.
27 tylated esters exhibited antiviral activity (50% effective concentration (EC50) ranging from 1.7 to 2
28 ) and compared the phenotypic sensitivities (50% effective concentration [EC50]) of mutant and wild-t
29 pe laboratory HIV-1 strain (HIV-1(WT)), with 50% effective concentrations (EC50s) of 3.0 to 49 nM, an
30 clovir (3-, 14-, and 3-fold increases in the 50% effective concentrations [EC50s], respectively).
32 er sensitivity to bortezomib than FL (median 50% effective concentration for viability, 209 nmol/L v
34 nst DENV-1-4 and DENV-1 ADE infections, with 50% effective concentrations in the low micromolar range
35 toxin in in vitro cytotoxicity assays with a 50% effective concentration of 0.65 ng/ml for the lead c
36 t, clemizole's antiviral effect is moderate (50% effective concentration of 8 microM against an HCV g
39 ogenous oxidative membrane damage lowers the 50% effective concentration of direct-acting antivirals
43 ed in this subject was 117 nM and the median 50% effective concentration value for a GT-1a H77c repli
44 96, F1609-0442, and F1750-0048) having EC50 (50% effective concentration) values of 4.8 +/- 2.3, 12.5