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1 AFP can be regarded as a problem of the large-scale mult
2 AFP can still be used in the surveillance of HCC in Indo
3 AFP confirms the performance evidenced in other studies,
4 AFP level was evaluated against patient characteristics,
5 AFP responders at 1 mo had better overall survival than
6 AFP response, radiological response rate, and disease co
7 AFP was incubated in Ab1-coated wells; unbound AFP was t
8 AFPs have gained a large interest for their use in antif
9 nt (P < 0.001); KPS improvement (P < 0.001); AFP improvement (P < 0.001)] and reduction of therapeuti
10 onders, at 8.5 mo versus 4.8 mo (P = 0.018); AFP responders at 3 mo had overall survival of 13.3 mo,
11 .35 95% confidence interval (CI) 1.35-4.09], AFP >100 ng/mL (2.14 95% CI 1.17-3.93), and F4 fibrosis
12 R >/= 5 (P < 0.0001, hazard ratio, HR: 6.2), AFP > 200 (P < 0.0001, HR: 3.8), and Size >3 cm (P < 0.0
13 ies, Gunma, Japan) and AFP (IMMULITE(R) 2000 AFP, Siemens Healthcare Diagnostics, Tarrytown, New York
14 could be expanded to the TTV (</=115 cm(3) )/AFP (</=400 ng/mL) criteria in centers with at least 8-m
15 t (Maximum Mid-Expiratory Flow, MMEF25-75%), AFP and CEA for never smokers, light and never smokers w
17 limited value In diagnosing nvHCC, Having a AFP value over 400 ng/ml was associated with aggressive
19 eptides, the assay can quantify low abundant AFP expression (0.5 ng) with good correlation with conve
21 ater than 18 months (HR, 1.6; P = 0.043) and AFP greater than 400 at HCC diagnosis (HR, 3.0; P < 0.00
23 ch as family history of lung cancer, CEA and AFP for light smokers, and lung function test (Maximum M
25 the APRI score in diagnosis of cirrhosis and AFP in the diagnosis of HCC was determined using AUROC a
26 ents within the Metroticket 2.0 criteria and AFP model <=2 points exhibited heterogeneous recurrence
27 ilan criteria, Metroticket 2.0 criteria, and AFP model cut-off <=2 points (all P < 0.001) with c-stat
29 EXT III, PRETEXT IV, metastatic disease, and AFP concentration of 100 ng/mL or lower at diagnosis.
32 criteria, macroscopic vascular invasion, and AFP score>2 were independent predictors of recurrence, w
33 o-Biological Laboratories, Gunma, Japan) and AFP (IMMULITE(R) 2000 AFP, Siemens Healthcare Diagnostic
36 Comparing the two groups, AUC for OPN and AFP were 0.51 (95 % CI: 0.39-0.63) and 0.79 (95 % CI: 0.
41 e vacuum infiltration of Drimys angustifolia AFPs into the star fruit allowed an initial cryoprotecti
43 ts were used to label one member of the anti-AFP pair (Ab2) via amine-amine coupling using glutaralde
44 the proposed AuNP/TNW/AuNP coupled with anti-AFP through the analysis of the photocurrent change.
45 e 5 cm or smaller, solitary lesion, baseline AFP level lower than 100 ng/dL, and Eastern Cooperative
47 we examine the molecular recognition between AFP and trehalose crystal interfaces using molecular dyn
55 ction in AFP from > 1,000 ng/mL to different AFP thresholds before LT on survival and HCC recurrence
56 ut nonmetastatic, HCC and initially elevated AFP, possibly enabling early therapy monitoring independ
57 measured in expression of PAPPA, FLT1, ENG, AFP, PGF, and LGALS14, but not LGALS13 or the lineage ma
58 the high-resolution structure of the entire AFP particle in the extended state, trace 11 protein cha
59 et that is classified by an extreme EpCAM(+) AFP(+) gene expression signature and associated with poo
62 erum 25OH-vitamin D, serum alfa-fetoprotein (AFP)) were performed on a cohort of 200 Egyptian CHC pat
64 rs, and 8 years or older; alpha fetoprotein (AFP) concentration of 100 ng/mL or lower and 101-1000 ng
65 er of 3 to 5 cm and serum alpha fetoprotein (AFP) greater than 100 ng/mL at transplant yielded a 50%
67 rveillance ultrasound and alpha fetoprotein (AFP) tests have minimal direct harm, downstream harms fr
68 antigen (CEA), bilirubin, alpha fetoprotein (AFP), and c-reactive protein (CRP) were identified and i
72 ikingly, patients with an alpha-fetoprotein (AFP) >=10 ng/mL and having used sirolimus for >=3 months
73 ltivariate analysis, only alpha-fetoprotein (AFP) >=200 ng/mL (P = 0.006) and large tumor size (P = 0
75 serum tumor markers were alpha-fetoprotein (AFP) 2.0 ng/mL, human chorionic gonadotropin (hCG) 151,1
76 sed two model biomarkers [alpha-fetoprotein (AFP) and cancer antigen 125 (CA125)] to demonstrate the
77 hrough the examination of alpha-fetoprotein (AFP) and ultrasound for patients at risk in developing H
78 or etiology of cirrhosis, alpha-fetoprotein (AFP) at liver transplant, tumor diameter, tumor patholog
79 REAT), which incorporates alpha-fetoprotein (AFP) at liver transplantation (LT), microvascular invasi
82 nsitive and specific than Alpha-fetoprotein (AFP) in the diagnosis of HCC among the White population.
86 tial necrosis, high serum alpha-fetoprotein (AFP) level (>100 ng/mL), and Barcelona Clinic Liver Canc
87 atients (542 men), median alpha-fetoprotein (AFP) level at the time of LT was 8.3 ng/mL; 9.4% had mic
88 em, tumor size, and serum alpha-fetoprotein (AFP) level were investigated using Cox proportional haza
90 losed a slightly elevated alpha-fetoprotein (AFP) of 12.3 ug/L (upper limit of normal, 8.0 ug/L), and
94 under optimal conditions, alpha-fetoprotein (AFP) was detected at a limit of detection of 1ngmL(-1) a
96 rface antigen (HBsAg) and alpha-fetoprotein (AFP) with the lowest concentration of naked-eye detectio
98 ciated gene expression of alpha-fetoprotein (AFP), Albumin (Alb), Glucose-6-phosphatase (G6Pc), SRY (
99 ntigen 19-9 (CA 19-9) and alpha-fetoprotein (AFP), commonly used to help in the diagnosis of iCCA and
101 with elevated circulating alpha-fetoprotein (AFP), low rate of necrosis/fibrosis after treatment, and
102 was associated with serum alpha-fetoprotein (AFP), tumor-node-metastasis (TNM) stage, and lymph node
104 umour burden score (TBS), alpha-fetoprotein (AFP), year of transplantation, underlying cause of cirrh
107 anel [APOH, ORM2, C3, and alpha-fetoprotein (AFP)] has proven to outperform AFP, the known HCC serum
109 as patients with negative alpha-fetoprotein (AFP; n = 1), resulting in 24 patients and 57 scans that
110 internal clathrate water network of the fish AFP Maxi, which extends to the protein's outer surface,
112 new national policy has been implemented for AFP > 1,000 ng/mL requiring a decrease to < 500 ng/mL be
113 cluded in the immunosensor modification (for AFP: 1st and 3rd approaches: 1.36fg/ml in comparison wit
114 we report a previously unidentified role for AFPs in effectively inhibiting trehalose precipitation i
116 ccording to Metroticket 2.0 model and French AFP model with Milan criteria serving as benchmark.
117 the spruce budworm Choristoneura fumiferana AFP, including stereo-specific binding and consequential
120 Of the 665 LT recipients, 457 (68.7%) had AFP-producing tumors, and 208 (31.3%) had non-AFP-produc
123 nadensis, and demonstrate that the hemolymph AFPs are crucial for inhibiting trehalose crystallizatio
130 etween fluorescence and clinically important AFP concentrations (range: 0-350 ng/mL with a correlatio
131 8% versus 67.0% for those with a decrease in AFP to 101-499 ng/mL (P < 0.001) and 88.4% for those wit
132 Low initial AFP level, a significant drop in AFP with DS and low tumor grade, favorably influence sur
133 n the proposed method and an ELISA method in AFP and CA125 measurements of serum samples were less th
134 ed to evaluate the effects of a reduction in AFP from > 1,000 ng/mL to different AFP thresholds befor
135 stricting LT to patients with a reduction in AFP from > 1,000 to < 500 ng/mL, validating the recently
137 Our data define a cognate ZBTB20 site in AFP promoter which mediates the postnatal repression of
141 with HCC recurrence: microvascular invasion, AFP at time of LT, and the sum of the largest viable tum
145 ded age, sex, liver disease diagnosis, MELD, AFP, NLR, radiographic Milan status, and number of LRT t
148 CA125) and linear ranges (0.2pg/mL-0.68ng/mL AFP and 0.003-25U/mL CA125) of this method are the same
150 d a ZBTB20-binding site at -104/-86 of mouse AFP gene, flanked by two HNF1 sites and two C/EBP sites
151 ot produce AFP (hereafter referred to as non-AFP-producing tumors), and to identify factors influenci
152 FP-producing tumors, and 208 (31.3%) had non-AFP-producing tumors (the maximum AFP level before an LT
153 with radiographically apparent HCC have non-AFP-producing tumors that have more favorable pathologic
156 ictors of recurrence among patients with non-AFP-producing tumors include radiologic (>2 tumors [HR,
157 nsplant HCC recurrence for patients with non-AFP-producing tumors is predicted by important radiologi
158 d recurrence lowest, among patients with non-AFP-producing tumors within the Milan criteria (71% surv
160 0 criteria (0.014, Z = 0.023; P = 0.509) nor AFP model (-0.014, Z = -0.021; P = 0.492) provided signi
162 ng/dL), 12 patients achieved restored normal AFP levels (<13 ng/dL) and exhibited median overall surv
165 r was successfully exploited for analysis of AFP in real human blood plasma, serum and urine sample.
171 rm maintenance in resource-poor countries of AFP surveillance as a platform for surveillance of vacci
173 mmunosensor exhibited sensitive detection of AFP with an ultrahigh sensitivity of 0.001 ng mL(-1) and
174 Moreover, the practical determination of AFP in human serum is also investigated, demonstrating i
176 nted polymer was also used for estimation of AFP in the concentration range of 3.96-80.0 ng mL(-1), w
181 ameters most associated with the increase of AFP >=10 ng/ml according to multivariate analysis were t
183 ated more than a decade ago that mixtures of AFP isoforms can exhibit synergistic enhancement of each
191 imilarly, the sensitivity and specificity of AFP were 62.9% and 93.3% at an ROC - derived optimum cut
193 health facilities) is a critical strategy of AFP surveillance systems for highly sensitive and timely
194 o vaccine introduction, and strengthening of AFP surveillance) that have contributed to the interrupt
198 en some controversies regarding the usage of AFP concerning its low sensitivity and specificity in de
200 otection, indicating that the application of AFPs can increase the quality of frozen star fruit.
201 ition (IRI) activity of all major classes of AFPs using cryoscopy, sonocrystallization, and recrystal
202 rowth inhibition by the different classes of AFPs: blocking fast ice growth requires rapid nonbasal p
208 -fetoprotein (AFP)] has proven to outperform AFP, the known HCC serum biomarker, alone, in this study
209 reporting non-polio acute flaccid paralysis (AFP) (OR = 1.13, 95% CI 1.02-1.26 for a 1-unit increase
210 ns of patients with acute flaccid paralysis (AFP) and sewage samples collected from 60 environmental
211 Surveillance for acute flaccid paralysis (AFP) is a fundamental cornerstone of the global polio er
212 fied with non-polio acute flaccid paralysis (AFP) reported through polio surveillance, information on
213 ors associated with acute flaccid paralysis (AFP) surveillance, routine immunization, and polio suppl
215 as limited by the small numbers of non-polio AFP cases in some districts, which was reflected by larg
218 te that the new fungal protease preparations AFP and FPII, bacterial protease preparation HT and the
219 fungal and bacterial protease preparations (AFP, FPII, F60K and HT) was evaluated over a range of pH
220 ng tumors or with tumors that do not produce AFP (hereafter referred to as non-AFP-producing tumors),
222 re, we characterize the antifeeding prophage AFP from Serratia entomophila by cryo-electron microscop
224 peptides inspired by the antifreeze protein (AFP) and antifreeze glycoprotein (AFGP) are attached ont
233 tective capabilities of antifreeze proteins (AFPs), we hypothesized that supplementation of islets wi
235 Overexpression of ABI5/ABF binding proteins (AFPs) results in extreme ABA resistance of seeds via mul
236 Overexpression of ABI5/ABF binding proteins (AFPs) results in extreme ABA resistance of seeds via mul
238 TCR that recognizes the HLA-A*02-restricted AFP(158-166) peptide, FMNKFIYEI, with an optimum balance
239 ermore, we present the first study revealing AFP glycopeptide signatures of individual HCC patients,
241 r improve the performance of the large-scale AFP by incorporating massive protein-protein network inf
242 l for End-stage Liver Disease (MELD) scores, AFP levels, and neutrophil-lymphocyte ratios (NLR); were
245 erval [CI] = 8.9, 114; P < .001), high serum AFP level (odds ratio = 4.4; 95% CI = 1.3, 16; P = .02),
247 group, the BCLC staging system and the serum AFP level were associated with PFS (P = 0.04) and OS (P
248 In the multivariate analysis, tumor size, AFP < 100 ng/mL and serum alkaline phosphatase were inde
251 tylase activity by trichostatin A suppressed AFP effects on a small fraction of the ABI5-regulated ge
253 hat supplementation of islets with synthetic AFP analog antiaging glycopeptide (AAGP) would enhance p
258 In multivariable analysis, a decrease in the AFP to 101-499 ng/mL was associated with a > 2-fold redu
259 Furthermore, we provide the structure of the AFP sheath-baseplate complex in a contracted state.
260 and shows preferential strong binding of the AFP to the fast growing surfaces of the sugar crystal.
262 Z (NINJA) protein, it was suggested that the AFPs interact with the co-repressor TOPLESS to inhibit A
263 Collectively, these results suggest that the AFPs participate in multiple mechanisms modulating ABA r
265 ariables: age, type of locoregional therapy, AFP, donor sex, body mass index, or nonalcoholic steatoh
267 ecause of the extensive resources devoted to AFP surveillance, multiple opportunities exist for addit
272 er for patients beyond Milan, but within TTV/AFP (16 of 38; 42.1%), than for those within Milan (49 o
278 s salts and alcohols, the advantage of using AFPs as an additive is that they do not alter the physic
279 h data on process indicators associated with AFP surveillance and routine immunization, showing stati
281 h radiographically apparent HCC lesions with AFP-producing tumors or with tumors that do not produce
282 hin Metroticket 2.0 criteria (75.3%) or with AFP model <=2 points (74.1%) was inferior to that observ
283 was not performed in 45.4% of patients with AFP > 1,000 ng/mL at LT versus 12.8% of those with AFP o
284 ility at 5 years was 35.0% for patients with AFP > 1,000 ng/mL versus 13.3% for patients with AFP of
287 p was modified to include only patients with AFP <400 ng/mL; these patients were compared to patients
289 > 1,000 ng/mL versus 13.3% for patients with AFP of 101-499 ng/mL and 7.2% for patients with AFP <= 1
291 s in LT for HCC, especially in patients with AFP-evidence of higher tumor activity, advocating partic
292 e, and recurrence highest, for patients with AFP-producing tumors outside the Milan criteria (40% sur
293 cteristics similar to those of patients with AFP-producing tumors, but, pathologically, they had fewe
296 Meier 5-year post-LT survival for those with AFP > 1,000 ng/mL at LT was 48.8% versus 67.0% for those
299 1,000 ng/mL at LT versus 12.8% of those with AFP of 101-499 ng/mL and 10.3% of those with AFP <= 100
300 tar fruits that were vacuum infiltrated with AFPs retained their drip loss constant after 15 days.