ライフサイエンスコーパス: AVP

1 AVP activates arginine vasopressin type 1A (V(1A))/Galph

2 AVP and OT signaling predominantly occur within a circui

3 AVP exerted the same effects on diestrous and proestrous

4 AVP from the SCN is found in regions important for the r

5 AVP increased extracellular-regulated kinase 1/2 (ERK1/2

6 AVP increases humans' willingness to cooperate.

7 AVP injected into wild-type mice enhanced and reduced, r

8 AVP is activated by two cofactors, the viral DNA and pVI

9 AVP stimulated GLP-1 and PYY release from primary cultur

10 AVP travels through the bloodstream to the kidney, where

11 AVP, initially synthesized as an inactive enzyme, requir

12 AVP, partially activated by being bound to DNA, excises

13 AVP-p demonstrates activity against viruses with the Old

14 AVP-p is unique among self-derived inhibitory peptides i

15 AVP-p may represent a potent, highly specific, novel the

16 AVP/cyclic adenosine monophosphate enhance the phosphory

17 Inhibition of the V(2) AVP receptor represses ENaC activity in Adx mice.

18 e potential therapeutic value of a new V1 a -AVP receptor partial agonist with a preferential splanch

19 tested the hypothesis that CREB3L1 activates AVP gene transcription.

20 lfide bond with AVP forming the fully active AVP-pVIc complex bound to DNA.

21 The persistent high urine volume after AVP administration was traced to a reduction in aquapori

22 l connectivity with the ventral pallidum, an AVP receptor-rich region previously associated with AVP-

23 icant positive association between Ang-2 and AVP index, MMP-2, Ang-1, and VEGF in SRA.

24 g immunohistochemistry, examined for 5HT and AVP afferent innervation/development to areas of the bra

25 s aggressive behavior and alters LAH 5HT and AVP development, yet only alterations in AVP afferent de

26 B-Raf and A-kinase anchoring protein 79, and AVP increased this interaction in ADPKD but not NHK cell

27 rences in AVP-ir fiber fractional areas, and AVP-ir cell body numbers, which were mainly observed in

28 n the structural differences between AVP and AVP-pVIc, we present a model that postulates that activa

29 cal modelling to investigate whether CRH and AVP promote distinct patterns of electrical excitability

30 ical modeling to investigate whether CRH and AVP promote distinct patterns of electrical excitability

31 Co-stimulation with CRH and AVP results in complex patterns of excitability includin

32 rease in excitability in response to CRH and AVP the patterns of electrical excitability and underlyi

33 he use of 5-HT-targeted drugs in females and AVP-targeted drugs in males.

34 e via AVP receptor (AVPR)2 in the kidney and AVP receptor 1A in vascular smooth muscle.

35 studying the role and relatedness of OT and AVP in the developing brain.

36 Reviewing the research about OT and AVP in these NDD suggests that altered OT pathways may b

37 1 (Fmr1) gene, resulting in decreased OT and AVP staining cells in some brain regions.

38 We review how the OT and AVP systems have been investigated in Autism Spectrum Di

39 appropriately phased to support rhythms, and AVP receptor signaling is required to impose circuit-lev

40 e-vasopressin (AVP) release: ( a) Thirst and AVP release are regulated by the classical homeostatic,

41 Finally, constant light increased VIP and AVP expression, but not VPAC2R.

42 In Ussing chambers, basolaterally applied AVP reduced colonic anion secretion and this effect was

43 The only approved AVP receptor agonist, desmopressin is indicated for the

44 homeostasis and behavior is problematic, as AVP is made in multiple nuclei in the hypothalamus (i.e.

45 dependent on circulating ovarian steroids as AVP no longer excited preoptic kisspeptin neurons in ova

46 Once particles are assembled, AVP-mediated cleavage facilitates the release of the mem

47 s analogue d(CH2)5[D-Tyr(Et2)-Ile4-Eda9]AVP (AVP(an)) have been synthesized using the technetium comp

48 Elevated baseline AVP level was independently predictive of mortality, but

49 There was no interaction of baseline AVP with treatment assignment in terms of survival (P=0.

50 Based on the structural differences between AVP and AVP-pVIc, we present a model that postulates tha

51 [Cl(-)]i is differentially regulated between AVP+ and VIP+ neurons-a low concentration of the loop di

52 versed by bumetanide, and furosemide blocked AVP release, both in vivo and in hypothalamic explants.

53 during the day than during the night in both AVP+ and VIP+ neurons.

54 Aldosterone-independent stimulation by AVP shifts the role of ENaC in the ASDN from protecting

55 that is cleaved at both N- and C-termini by AVP.

56 ive to modulation of systemic and/or central AVP release through PVN inputs to the posterior pituitar

57 t, when subjects make the risky Stag choice, AVP down-regulates the BOLD signal in the left dorsolate

58 tedly, estrogen is found to permit circadian AVP signaling at preoptic kisspeptin neurons rather than

59 the brain and exhibits a prominent circadian AVP rhythm.

60 onate for these robust levels of circulating AVP at birth.

61 The 99mTc(NS3)(CN-AVP) and 99mTc(NS3)(CN-AVP(an)) ability of binding to small-cell lung cancer (S

62 he novel vasopressin conjugate 99mTc(NS3)(CN-AVP(an)) is a desirable compound for imaging oncogene re

63 The 99mTc(NS3)(CN-AVP) and 99mTc(NS3)(CN-AVP(an)) ability of binding to sm

64 Consequently, AVP failed to induce the sustained intracellular Ca(2+)

65 In contrast, AVP promotes an increase in single spike frequency, a me

66 Neonatal CSF AVP concentrations were significantly lower among ASD ca

67 on, the stimulatory effect of 1-desamino-8-D-AVP and the defect in AC6(-/-) mice seem to be restricte

68 umerous regions in which males have a denser AVP-immunoreactive innervation than females.

69 of its analogue d(CH2)5[D-Tyr(Et2)-Ile4-Eda9]AVP (AVP(an)) have been synthesized using the technetium

70 periments, male participants received either AVP or placebo intranasally and made decisions with fina

71 adjusting for baseline covariates, elevated AVP levels were associated with increased all-cause mort

72 sed the proportion of patients with elevated AVP (P<0.001), but this had no effect on mortality (haza

73 bsence of aldosterone combined with elevated AVP release compromises normal feedback regulation of EN

74 ion of PDE4, and inhibition of PDE1 enhanced AVP-induced ERK activation.

75 nfirm that Caprin-2 over-expression enhances AVP mRNA abundance and poly(A) tail length.

76 rning for Antiviral Peptide Prediction (FIRM-AVP) approach achieves a higher accuracy than either the

77 molality or copeptin (a surrogate marker for AVP).

78 smolality and copeptin (surrogate marker for AVP).

79 ow a previously unidentified causal role for AVP in social approach behavior in humans, as establishe

80 out the neonatal periphery suggest roles for AVP in modulating peripheral physiology and development

81 rnal capsid cement protein and substrate for AVP, is cleaved at two sites, one of which is near the N

82 on of copeptin, an established surrogate for AVP, with parameters of renal function and morphology in

83 However, AVP also causes dephosphorylation of AQP2 at S261.

84 However, AVP-mediated protection against H/R was elicited only vi

85 Remarkably, however, AVP signaling was critically dependent on circulating ov

86 he in females and activation of hypothalamic AVP neurons in males.

87 Importantly, AVP and OT signaling within the SBNN has been shown to d

88 In AVP, however, His-54 Ndelta1 is 7.0 A away from Cys-122

89 In AVP, however, Tyr-84 is more than 11 A away from its pos

90 In AVP-pVIc, the general base His-54 Ndelta1 is 3.9 A away

91 In AVP-pVIc, Tyr-84 forms a cation-pi interaction with His-

92 and AVP development, yet only alterations in AVP afferent development within the LAH correlate with t

93 , for the first time, the role of L-cells in AVP regulated intestinal fluid secretion, potentially li

94 in concentrations correlated with changes in AVP concentrations in controls and patients.

95 lasmalemmal and cytoplamic NK3R densities in AVP-labeled but not in OC-labeled dendrites.

96 nificantly increased nuclear NK3R density in AVP-labeled somata but not in OC-labeled somata.

97 is due in part to age and sex differences in AVP and OT synthesis within the SBNN.

98 nd female mice to examine sex differences in AVP innervation.

99 ions) and sex (10 subregions) differences in AVP-ir fiber fractional areas, and AVP-ir cell body numb

100 However, their subcellular distribution in AVP or OC neurons of the PVN and plasticity following re

101 es nuclear NK3R translocation exclusively in AVP neurons.

102 risingly, we find that circadian function in AVP neurons, not VIP neurons, is essential for autonomou

103 ditions, NK3Rs were predominantly located in AVP neurons, however sparsely distributed in OC neurons

104 superoxide generating NADPH oxidase (NOX) in AVP-expressing hypothalamic paraventricular nucleus (PVN

105 is more than 11 A away from its position in AVP-pVIc.

106 tigated intracellular chloride regulation in AVP and VIP-expressing SCN neurons and found evidence su

107 relationship between baseline and trends in AVP with outcomes in patients hospitalized for worsening

108 PVN neurons, whereas robust upregulation in AVP neurons accompanied DH and SL rats.

109 ologic states characterized by inappropriate AVP secretion and positive water balance.

110 into rat SONs and PVNs resulted in increased AVP biosynthesis.

111 Tolvaptan treatment increased AVP levels during follow-up, but this incremental increa

112 phase of sepsis is associated with increased AVP levels and suppressed thirst.

113 on of NKCC2 with lipid rafts facilitates its AVP-induced apical translocation and activation at the s

114 concentration in Brattleboro rats that lack AVP.

115 iral-rescue approach to "cure" magnocellular AVP cells of their Brattleboro mutation.

116 ea, an increase in the size of magnocellular AVP neurons and a higher concentration of 5-HT and dopam

117 Our results suggest that the BNST/MeA AVP system innervates regions containing major modulator

118 As observed in cryo-electron micrographs, AVP-p treatment causes morphological changes consistent

119 ake of large amounts of water despite normal AVP secretion and action.

120 ll line cAMP accumulation), producing 57% of AVP's maximal activity (EC50 = 2.7 nM) and is not a V1a

121 asma membrane localization in the absence of AVP.

122 um-induced NDI by potentiating the action of AVP on the CD.

123 t a model that postulates that activation of AVP by pVIc occurs via a 62-amino acid-long activation p

124 There is a conundrum in the activation of AVP in that AVP and pVI are sequence-independent DNA-bin

125 that conundrum by showing that activation of AVP takes place on the one-dimensional contour of DNA.

126 was prevented by pharmacological blockade of AVP receptors.

127 However, a thorough characterization of AVP and OT-immunoreactive (ir) fibers and cell bodies ac

128 ntrating ability by augmenting the effect of AVP on the kidney and ameliorates lithium-induced NDI by

129 hydration-evoked GABA-mediated excitation of AVP neurons was reversed by bumetanide, and furosemide b

130 adal steroid hormone-dependent expression of AVP in the BNST and MeA and electrolytic lesions to elim

131 ell established as an important co-factor of AVP, the role of the N-terminal fragment, pVIn, is curre

132 To understand the function of AVP, it is essential to know the site of origin of vario

133 on of AQP2 in principal cells independent of AVP.

134 ed aggression in males, whereas injection of AVP inhibited aggression in females and stimulated aggre

135 An i.p. injection of AVP to LXRbeta(-/-) mice revealed a partial kidney respo

136 of this study is to identify the location of AVP receptor 1a (AVPR1A) sites as potential peripheral t

137 and polyuria seen in Hom rats due to loss of AVP facilitation of water reabsorption in the kidney.

138 dolescent Hom rats is not due to the loss of AVP function in magnocellular cells or a side effect of

139 ypoaroused phenotype could be due to loss of AVP in magnocellular cells that supply AVP to the periph

140 In conclusion, a partial or complete loss of AVP osmoregulation occurs in patients with SIAD.

141 Manipulation of AVP or 5-HT signalling can rescue the shoaling phenotype

142 ptin concentration as a surrogate measure of AVP concentration, patients with SIAD could be grouped a

143 caused by a defect in central production of AVP.

144 We thus identify CREB3L1 as a regulator of AVP transcription in the rat hypothalamus.

145 affinities and Ca(2+) signaling responses of AVP, Pro(8)-OXT and Leu(8)-OXT at human, macaque, and ma

146 Sliding of AVP-pVIc complexes along DNA illustrates a new biochemic

147 Comparison of the structure of AVP with that of an active form, the AVP-pVIc complex, r

148 In vaginally delivered neonates, a surge of AVP is released into the bloodstream at levels exceeding

149 P-1) and peptide YY (PYY) may be a target of AVP and contribute to the control of fluid balance.

150 1A) sites as potential peripheral targets of AVP in the neonatal mouse.

151 retic bumetanide had differential effects on AVP+ and VIP+ neurons, while blocking the KCCs with VU02

152 males in the near plasmalemmal p47(phox) on AVP dendrites seen in the present study.

153 aline stimulation together with copeptin (or AVP) measurement.

154 , unlike the static pattern observed for OT, AVP innervation of the forebrain SBNN appears to undergo

155 alian PVN (CCK, CRH, ENK, NTS, SS, VIP, OXT, AVP), we provide the first 3D arrangement map of NPO neu

156 Here, we tested whether OXT/AVP ligands show differential levels of crosstalk at pri

157 s the hypothesis that central, parvocellular AVP mechanisms underlie the regulation of arousal during

158 The anterior visual pathway (AVP) conducts visual information from the medulla of the

159 it that we call the anterior visual pathway (AVP).

160 treatment failure, we identified a peptide, AVP-p, derived from the fusion glycoprotein of a nonpath

161 We have identified a GP2-derived peptide, AVP-p, with antiviral activity and no acute cytotoxicity

162 rk in concert with the well-known peripheral AVP actions of controlling homeostasis and stress respon

163 Airway vascular permeability (AVP) index was also assessed.

164 lity, urine sodium concentration, and plasma AVP levels.

165 al intracellular Ca(2+) levels and prevented AVP-induced translocation of aquaporin 2, further sugges

166 is mediated by the virally encoded protease AVP.

167 y the virally encoded adenovirus proteinase (AVP) before the virus particle becomes infectious.

168 ly, activation of the adenovirus proteinase (AVP) during maturation and endosome escape following cel

169 The adenovirus proteinase (AVP), the first member of a new class of cysteine protei

170 adenovirus infection, the viral proteinase (AVP) becomes activated to process virion precursor prote

171 d a decrease in cytoplasmic p47(phox) in PVN AVP dendrites.

172 the present study, densities of NK3Rs in PVN AVP- or OC-labeled somatodendritic profiles were measure

173 munoreactive projections; we also quantified AVP-immunoreactive fiber density in gonadectomized and s

174 We therefore quantified AVP- and OT-ir fibers and cell bodies in 22 subregions o

175 ing a functional Avp gene and promoter (rAAV-AVP) rescued AVP within magnocellular cells and fiber pr

176 Rat AVP promoter deletion constructs revealed that CRE-like

177 3L1 (CREB3L1CA) induce the expression of rat AVP promoter-luciferase reporter constructs, whereas a d

178 for the arginine-vasopressin V(2) receptor (AVP V(2)R) was synthesized using "Click" chemistry.

179 An antagonist of AVPR1B reduced AVP-triggered hormone secretion from murine and human ce

180 l to the B-Raf/MEK/ERK pathway and regulates AVP-induced proliferation of ADPKD cells.

181 nal Avp gene and promoter (rAAV-AVP) rescued AVP within magnocellular cells and fiber projections of

182 r classes of peptidergic neurons in the SCN: AVP (arginine vasopressin) and VIP (vasoactive intestina

183 dized peptide (METx) would lead to selective AVP receptor agonism.

184 ss of AVP in magnocellular cells that supply AVP to the peripheral circulation and project to limbic

185 OXT produce a less efficacious response than AVP at human AVPR1a and higher efficacious response than

186 AVPR1a and higher efficacious response than AVP at marmoset AVPR1a.

187 eceptor binding and membrane fusion and that AVP-p may represent a viable therapeutic strategy for ar

188 We found that AVP binds with higher affinity than OXT across AVPR1a, a

189 a conundrum in the activation of AVP in that AVP and pVI are sequence-independent DNA-binding protein

190 s and cryo-electron microscopy indicate that AVP-p induces premature activation of viral fusion prote

191 In conclusion, we propose that AVP activates L-cell AVPR1B, causing GLP-1 and PYY secre

192 a(2+)]i) in multiple cells and revealed that AVP increased [Ca(2+)]i in >80% of diestrous kisspeptin

193 Together, these studies show that AVP exerts a potent and direct stimulatory influence upo

194 By means of Ussing chambers, we show that AVP reduced colonic anion secretion, although this was b

195 slices from kisspeptin-GFP mice showed that AVP dose-dependently increased the firing rate of most k

196 These results suggest that AVP has a pleiotropic role in renal function and may fav

197 Recent evidence suggests that AVP may have additional effects on renal function and fa

198 The AVP bears a fundamental resemblance to the sky-compass p

199 This is mediated by the AVP receptor 1B, which is highly enriched in colonic L-c

200 ture of AVP with that of an active form, the AVP-pVIc complex, reveals why AVP is inactive.

201 ing of transmembrane proteins, including the AVP-regulated water channel, aquaporin 2.

202 ticle, we have analyzed the formation of the AVP from early larval to adult stages.

203 ship of primary and secondary neurons of the AVP lineages.

204 d by extension of the 3' poly(A) tail of the AVP mRNA, and the up-regulation of the expression of RNA

205 The immature fiber tracts of the AVP, formed by secondary neurons of lineages DALcl1/2 an

206 promotes AQP2 trafficking independent of the AVP-PKA axis.

207 in ccRCC, and suggest that inhibitors of the AVP-V2R pathway, including the FDA-approved drug Tolvapt

208 An activated adenovirus proteinase, the AVP-pVIc complex, was shown to slide along viral DNA wit

209 tically stimulated hypothalamus shortens the AVP mRNA poly(A) tail at the same time as reducing trans

210 und to DNA, excises pVIc, which binds to the AVP molecule that cut it out.

211 Direct binding of CREB3L1 to the AVP promoter was shown by chromatin immunoprecipitation

212 ontrols (n = 33 total), and quantified their AVP and oxytocin (OXT) concentrations.

213 inate the SCN, effectively eliminating those AVP-immunoreactive projections; we also quantified AVP-i

214 1) = 1.45 x 10(6) bp(2)/s, until it binds to AVP also on the same DNA molecule.

215 Here we show that Caprin-2 binds to AVP mRNAs, and that lentiviral mediated shRNA knockdown

216 suggesting impaired sensitivity of the CD to AVP in SHR-A3.

217 a larger effect on VIP+ neurons compared to AVP+ neurons.

218 In contrast to AVP, we observed no age or sex differences in OT-ir fibe

219 which the kidney responds inappropriately to AVP.

220 n undermining coparenting and was related to AVP.

221 as nephrogenic DI results from resistance to AVP in the kidneys.

222 d PDEs, also induced a mitogenic response to AVP in NHK cells, similar to the effect of restricting i

223 mote its apical translocation in response to AVP stimulation and low chloride hypotonic stress.

224 ducing ERK1/2 phosphorylation in response to AVP stimulation.

225 The associations were specific to AVP, as ASD cases and controls did not differ in neonata

226 with high levels of pS256, despite unchanged AVP and cAMP.

227 n dissecting molecular mechanisms underlying AVP-mediated water reabsorption, evidenced by our identi

228 ent analysis examined baseline and follow-up AVP levels in 3196 EVEREST patients with valid AVP measu

229 nted the lithium-induced increase in urinary AVP excretion and suppressed the lithium-induced increas

230 V1a -AVP receptor expression in rats with cirrhosis and ascit

231 V1a -AVP receptor partial agonism could be a useful pharmacol

232 The effect of the V1a -AVP receptor partial agonist on PP was associated with a

233 P levels in 3196 EVEREST patients with valid AVP measurements.

234 Vasopressin (AVP) is both a neuroendocrine hormone located in magnoce

235 Vasopressin (AVP) signaling via PKA and other kinases activates NKCC2

236 Vasopressin (AVP) stimulates ENaC.

237 h oxytocin receptors (OXTR) and vasopressin (AVP) 1a receptors (AVPR1a).

238 ment of the serotonin (5HT) and vasopressin (AVP) neural systems modulating this behavior using puber

239 hool, assayed oxytocin (OT) and vasopressin (AVP), and measured coparenting and child behavior proble

240 a greater increase in basal and vasopressin (AVP)-stimulated cAMP levels and Cl(-) secretion by ADPKD

241 Defining how arginine vasopressin (AVP) acts centrally to regulate homeostasis and behavior

242 Arginine vasopressin (AVP) affects kidney function via vasopressin V2 receptor

243 with the neuropeptide arginine vasopressin (AVP) and clock proteins (PER2 and BMAL1), supporting tha

244 urohypophyseal hormone arginine vasopressin (AVP) and in the expression of oxidative stress.

245 Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential rol

246 Circulating levels of arginine vasopressin (AVP) are elevated during hypovolemia and during cardiac

247 Oxytocin (OT) and arginine vasopressin (AVP) are two small, related neuropeptide hormones found

248 nt on the neuropeptide arginine vasopressin (AVP) because it was prevented by pharmacological blockad

249 tain a mutation in the arginine vasopressin (AVP) gene, exhibit lower behavioral arousal than their h

250 Arginine vasopressin (AVP) has a key role in osmoregulation by facilitating wa

251 iciency of the hormone arginine vasopressin (AVP) in the pituitary gland or the hypothalamus, whereas

252 e antidiuretic hormone arginine vasopressin (AVP) increases in the hypothalamus, and this is accompan

253 Arginine vasopressin (AVP) is a neurohypophysial hormone regulating hydrominer

254 "social" neuropeptide arginine vasopressin (AVP) is significantly lower in pediatric ASD cases vs. c

255 Arginine vasopressin (AVP) levels are elevated in proportion to heart failure

256 y elevated circulating arginine vasopressin (AVP) levels in SHR-A3 compared with SHR-B2.

257 ncluding VIP, GRP, and arginine vasopressin (AVP) neurons, with each ipRGC innervating specific subdo

258 The neuropeptide arginine vasopressin (AVP) plays significant roles in maintaining homeostasis

259 ling lipidized peptide arginine vasopressin (AVP) receptor agonist, that had not been designed as a p

260 Synthetic arginine vasopressin (AVP) receptor agonists able to induce systemic and mesen

261 Arginine vasopressin (AVP) regulates fluid balance and blood pressure via AVP

262 se in water intake and arginine vasopressin (AVP) secretion to promote fluid expansion and maintain b

263 Arginine vasopressin (AVP) stimulates the release of enteroendocrine L-cell de

264 renal collecting duct, arginine vasopressin (AVP) stimulates the synthesis of cAMP, leading to signal

265 sing hormone (CRH) and arginine vasopressin (AVP) to control the release of adrenocorticotrophic horm

266 sing hormone (CRH) and arginine vasopressin (AVP) to control the release of adrenocorticotrophin horm

267 e antidiuretic hormone arginine vasopressin (AVP) underlies diabetes insipidus, which is characterize

268 inct binding sites for arginine vasopressin (AVP) within its V2 -receptor (V2 R).

269 Here we show that arginine vasopressin (AVP), a neuropeptide that mediates complex mammalian soc

270 d serum sodium, plasma arginine vasopressin (AVP), and plasma copeptin concentrations from 50 patient

271 a surrogate marker of arginine vasopressin (AVP), to be associated with increased risk for type 2 di

272 ption is controlled by arginine vasopressin (AVP), which binds to V2 receptors, resulting in protein

273 a central modulator of arginine vasopressin (AVP)-induced water transport in the renal collecting duc

274 ction of parvocellular arginine vasopressin (AVP)-positive neurons in the preoptic area, an increase

275 neuropeptide hormone, arginine vasopressin (AVP).

276 eness of the kidney to arginine vasopressin (AVP).

277 t serotonin (5-HT) and arginine-vasopressin (AVP) act in opposite ways in the hypothalamus to regulat

278 Arginine-vasopressin (AVP) binding to vasopressin V2 receptors promotes redist

279 e elevated circulating arginine-vasopressin (AVP) levels, we examined whether AVP can affect the skel

280 us output neuropeptide arginine-vasopressin (AVP) on the activity of preoptic area kisspeptin neurons

281 , taste for water, and arginine-vasopressin (AVP) release: ( a) Thirst and AVP release are regulated

282 The neuropeptides vasopressin (AVP) and oxytocin (OT) have been implicated in the regul

283 99mTc-labeled conjugates of the vasopressin (AVP) peptide and of its analogue d(CH2)5[D-Tyr(Et2)-Ile4

284 lay stress information include vasopressin- (AVP) and oxytocin- (OC) containing neurons of the parave

285 gulates fluid balance and blood pressure via AVP receptor (AVPR)2 in the kidney and AVP receptor 1A i

286 vo environment, heat-disrupted ts-1 virions, AVP-pVIc complexes processed five different precursor pr

287 In vivo, in heat-disrupted immature virus, AVP was also activated by pVI in DNA-dependent reactions

288 In vitro, AVP-pVIc complexes processed a purified virion precursor

289 Whether AVP also affects kidney structure in the general populat

290 asopressin (AVP) levels, we examined whether AVP can affect the skeleton directly as yet another comp

291 We next examined whether AVP signaling in kisspeptin neurons was time and ovarian

292 tive form, the AVP-pVIc complex, reveals why AVP is inactive.

293 anding the features that are associated with AVP activity is a core need to identify and design new A

294 eptor-rich region previously associated with AVP-mediated social reward processing in mammals.

295 pVIc then forms a disulfide bond with AVP forming the fully active AVP-pVIc complex bound to D

296 Pretreatment of H9c2 cells with AVP significantly reduced H/R-induced cell death and cas

297 show that CREB3L1 mRNA levels correlate with AVP transcription level in SONs and PVNs following sodiu

298 ly, increases in expression in parallel with AVP expression in supraoptic nuclei (SONs) and paraventi

299 ivity in H9c2 myoblasts after treatment with AVP.

300 ency, either globally or specifically within AVP-expressing neurons, developed central diabetes insip