ライフサイエンスコーパス: Alder

1 Alder buckthorn (Frangula alnus) is one of Ireland's rar

2 e distinct reactions: one group catalyses an Alder-ene reaction that was, to our knowledge, previousl

3 cycloadditions was published the year before Alder's study of the reaction of diazomethane and dimeth

4 Comparable results were obtained for Ben Alder and Ben Gairn berries.

5 Diels-Alder cyclization of diverse diene-dienophile reactive p

6 Diels-Alder reaction occurs via a concerted mechanism if the d

7 vantage of the decarbonylative [4 + 2] Diels-Alder cycloaddition reaction between ethynyl and tetraph

8 which may proceed as a concerted [4+2] Diels-Alder reaction or a stepwise [6+4] cycloaddition followe

9 The reaction process involves [4+2] Diels-Alder, retro-Diels-Alder, and 1-1' coupling reactions, a

10 d by force-dependent dissociation of a Diels-Alder adduct of anthracene and maleimide.

11 and increased biological activity of a Diels-Alder cyclized (DAC) RGD peptide.

12 derivative were synthesized by using a Diels-Alder cycloaddition followed by an addition-elimination

13 post-assembly modification (PAM) via a Diels-Alder cycloaddition of the anthracene panels of the cage

14 This reaction sequence proceeds via a Diels-Alder cycloaddition reaction catalyzed by dimethylalumin

15 fer of stereochemical information in a Diels-Alder cycloaddition through a point-chirality, axial-chi

16 which is immediately intercepted by a Diels-Alder cycloaddition.

17 dergoes a wide range of reactions as a Diels-Alder diene, dienophile, and [2 + 2] addend.

18 quantitatively reproduce the KIEs in a Diels-Alder reaction and a catalytic glycosylation.

19 a natural enzyme evolved to catalyze a Diels-Alder reaction and shows how catalysis is achieved.

20 sence of light with suitable enes in a Diels-Alder reaction and undergoes a transformation into imine

21 s of 2,2'-bis(naphthoquinones) using a Diels-Alder reaction of conjugated ketene silyl acetals with b

22 eatures of our route are as follows: a Diels-Alder reaction of masked o-benzoquinone to assemble the

23 e exhibits exceptional reactivity as a Diels-Alder reaction partner and engages in [4 + 2] cycloaddit

24 s was synthesized using as key steps a Diels-Alder reaction to generate a highly substituted bicyclo[

25 ric size and diastereoselectivity in a Diels-Alder reaction.

26 ere successfully synthesized through a Diels-Alder/oxidative cyclodehydrogenation approach.

27 ticipate in a second stage acylnitroso Diels-Alder cycloaddition.

28 ieved via an intramolecular amidofuran Diels-Alder cycloaddition/rearrangement followed by an iminium

29 eotides employing Michael addition and Diels-Alder cycloaddition reactions.

30 -phase chemistry for the synthesis and Diels-Alder reaction of Fmoc-protected azopeptides has been de

31 on the 1,3-dipolar cycloadditions and Diels-Alder reactions owing to their excellent reaction kineti

32 sms of various electrocyclizations and Diels-Alder reactions.

33 e recently proposed bis-pericyclic and Diels-Alder routes is blurred, and favorable transition states

34 The reactions proceed via an aryne Diels-Alder (ADA) reaction, followed by a facile aromatization

35 lkylidenecarbenes, were intercepted as Diels-Alder adducts.

36 ecently developed catalytic asymmetric Diels-Alder (DA) reactions of cinnamate esters with cyclopenta

37 olyol chain, a Ti-catalyzed asymmetric Diels-Alder reaction to generate the cis-decalin skeleton, and

38 alyst for iminium-ion-based asymmetric Diels-Alder reactions following a rational design approach.

39 The thermal 6pai aza-Diels-Alder cycloadditions between alpha-oxoketenes, in situ d

40 The mechanism of the aza-Diels-Alder reaction catalyzed by tetraalkylammonium or trialk

41 The aza-Diels-Alder reaction of various alkenes and in situ formed 1-a

42 etical study of the intermolecular Aza-Diels-Alder reaction using 5-aminopyrrole as a building block

43 electric fields (EEFs) on the same aza-Diels-Alder reaction, demonstrating that very strong EEFs woul

44 Thermal asymmetric aza-Diels-Alder reactions also proceeded in good yields and with h

45 edox catalysis of radical cation based Diels-Alder cycloadditions mediated by the first-row transitio

46 retained, as evidenced in a benchmark Diels-Alder reaction.

47 lds several three-dimensional bicyclic Diels-Alder adducts.

48 A key biomimetic Diels-Alder dimerization was found to occur at ambient tempera

49 wo ester substituents were prepared by Diels-Alder cycloadditions of cyclopentadiene with dimethyl fu

50 for the fusion of additional rings by Diels-Alder reactions.

51 t cucurbit[7]uril (CB[7]) can catalyse Diels-Alder reactions for a number of substituted and unreacti

52 al mol(-1)) and identify the catalytic Diels-Alder proficiencies (>80% accuracy) of two homologous Pd

53 a perfect molecular vessel to catalyze Diels-Alder reactions of 9-hydroxymethylanthracene with N-subs

54 The lithium cation Li(+)-catalyzed Diels-Alder (DA) reactions of benzene toward a series of acety

55 recently reported Lewis acid-catalyzed Diels-Alder reactions of arylallenes and acrylates were studie

56 entative photocatalytic radical cation Diels-Alder reaction.

57 hway suggest that a stepwise, cationic Diels-Alder cycloaddition is operative.

58 In the classic Diels-Alder [4 + 2] cycloaddition reaction, the overall degree

59 For example, in the classic Diels-Alder reaction, butadiene and ethylene combine to produc

60 identical withCR) for use in classical Diels-Alder (DA) reactions (with 1,3-cyclopentadiene).

61 ion flow in water, while the classical Diels-Alder mechanism contributes only approximately 17%.

62 rrier of 22 kcal/mol for the concerted Diels-Alder process and provide no evidence of a competitive s

63 as maleimides, through a conventional Diels-Alder reaction.

64 ired the development of a Claisen/Cope/Diels-Alder cascade reaction.

65 hetic gain in a cascade cross-coupling/Diels-Alder reaction, delivering borylated or non-borylated ca

66 ons as 2pi or 4pi components (covering Diels-Alder and 1,3-dipolar cycloadditions).

67 [4+2] cycloadditions (Diels-Alder reactions) have been widely used in organic synthe

68 omorphone by oxidative dearomatization/Diels-Alder cycloaddition was investigated.

69 ly prepared by using the photo-dehydro-Diels-Alder (DDA) reaction, access to (1,7)naphthalenophanes b

70 M06-2X) studies of a series of dehydro-Diels-Alder (DDA) reactions.

71 t and selective normal electron-demand Diels-Alder (DA) reactions following its incorporation into an

72 However, the inverse electron-demand Diels-Alder (DAinv) reaction between tetrazine (Tz) and norbor

73 ion (SPAAC) or inverse-electron-demand Diels-Alder (IE-DA) reactions.

74 bioorthogonal inverse-electron-demand Diels-Alder (IEDDA) cleavage reaction between tetrazine and tr

75 The inverse electron-demand Diels-Alder (IEDDA) cycloaddition, which was performed overnig

76 openes in an inverse electronic demand Diels-Alder (IEDDA) cycloaddition-cycloreversion sequence with

77 The emerging inverse electron demand Diels-Alder (IEDDA) reaction stands out from other bioorthogon

78 engaged in the inverse electron demand Diels-Alder (iEDDA) reaction with cyclooctyne.

79 ia a no-rinse, inverse electron-demand Diels-Alder (IEDDA) reaction, enabling their immediate visuali

80 ork reports an inverse electron demand Diels-Alder (iEDDA)-type reaction to synthesize 1,3,5-trizines

81 train-promoted inverse electron-demand Diels-Alder cycloaddition (SPIEDAC) targeted to cyclopropene-l

82 rotein through inverse electron demand Diels-Alder cycloaddition with subsequent double retro-Diels-A

83 train-promoted inverse electron-demand Diels-Alder cycloaddition, that is, tetrazine ligation, is rep

84 Inverse-electron demand Diels-Alder cycloadditions have emerged as important bioorthog

85 dicated on the inverse electron demand Diels-Alder reaction as well as the use of this approach to vi

86 thiols and the inverse-electron demand Diels-Alder reaction between tetrazine and trans-cyclooctene (

87 cations of the inverse electron demand Diels-Alder reaction is provided that have been conducted in o

88 intracellular inverse-electron-demand Diels-Alder reaction with a suitable dienophile.

89 bioorthogonal inverse electron-demand Diels-Alder reaction.

90 line-catalyzed inverse-electron-demand Diels-Alder reaction.

91 by means of an inverse-electron-demand Diels-Alder reaction.

92 Inverse electron demand Diels-Alder reactions between s-tetrazines and strained dienop

93 bioorthogonal inverse-electron demand Diels-Alder reactions involving 1,2,4,5-tetrazines derivatives

94 e mechanism of inverse electron-demand Diels-Alder reactions of 1,2,3-triazines, and that these mecha

95 talysis of the inverse electron demand Diels-Alder reactions of heterocyclic azadienes has been intro

96 vestigated the inverse electron-demand Diels-Alder reactions of trans-cyclooctene (TCO) and endo-bicy

97 These inverse electron-demand Diels-Alder reactions of triazines have wide applications in b

98 f well-behaved inverse electron demand Diels-Alder reactions where it preferentially reacts with elec

99 adiene and the inverse electron-demand Diels-Alder reactions with 3,6-bis(trifluoromethyl)tetrazine w

100 The normal electron-demand Diels-Alder reactions with cyclopentadiene and the inverse ele

101 described employing diastereoselective Diels-Alder and selenocyclization reactions, starting from (R)

102 ubstrate-controlled diastereoselective Diels-Alder reaction with a different dienophile to form 2-fol

103 Ps, followed by the diastereoselective Diels-Alder reaction with N-aryl maleimides furnishing isoquin

104 gs, the un-rearranged dibenzothiophene Diels-Alder adduct is isolated in every instance.

105 imetic total synthesis of the dimeric, Diels-Alder natural product griffipavixanthone from a readily

106 nzo[m]tetraphene, by means of a double Diels-Alder reaction between styrene and a versatile benzodiyn

107 We further report that double Diels-Alder reactions under solvent-free condition provide fac

108 We demonstrate a C-F bond driven Diels-Alder reaction of a fluorinated dienophile and a borole

109 c sequence features a highly effective Diels-Alder reaction using a carbamate-substituted siloxy dien

110 capable of unlocking new and efficient Diels-Alder reactions would have major impact.

111 ize the origin of the enantioselective Diels-Alder reaction (DA) of o-hydroxystyrene and azlactone ca

112 his study is a highly enantioselective Diels-Alder reaction of a versatile cyclic carbamate siloxy di

113 These data establish Diels-Alder cyclization as a versatile approach to stabilize d

114 Few examples of oximino ether Diels-Alder reactions have been reported previously, and norma

115 te disfavored enolate addition and exo Diels-Alder reactions enantioselectively.

116 in one step, and a stereoselective exo-Diels-Alder reaction to form the 6-membered ring.

117 A first Diels-Alder condensation followed by a Stille cross-coupling i

118 Asymmetric syntheses of the flavonoid Diels-Alder natural products sanggenons C and O have been achi

119 on system, affording a pro-fluorescent Diels-Alder product that, on demand, converts into an intensiv

120 to-type cyclization followed by 6-fold Diels-Alder cycloaddition, C216 was obtained by oxidative cycl

121 Outcomes are exemplified for Diels-Alder cycloadditions, oxidative addition of bonds by tra

122 hable electrostatic organocatalyst for Diels-Alder reactions.

123 to 2,3-dimethyl-1,3-butadiene to form Diels-Alder product 3 with a zero-order dependence on diene.

124 dimerization sequence to afford formal Diels-Alder adducts that undergo a smooth gold-catalyzed doubl

125 s subsequently undergo either a formal Diels-Alder cycloaddition or a competitive Michael addition/re

126 into enantioselective enzymatic formal Diels-Alder reactions.

127 polymer (3D p-POP) using catalyst-free Diels-Alder cycloaddition polymerization followed by acid-prom

128 ered rings are readily accessible from Diels-Alder reactions, cycloadditions that generate five-membe

129 antioselective prototropic shift/furan Diels-Alder (IMDAF) cascade to construct the ACD tricyclic cor

130 talyzed formation of asymmetric hetero Diels-Alder adducts.

131 gel condensation/intramolecular hetero Diels-Alder reaction using O-(arylpropynyloxy)-salicylaldehyde

132 ly arise from an intramolecular hetero Diels-Alder reaction.

133 red phosphorus heterocycles via hetero Diels-Alder reactions.

134 olecular Diels-Alder (IMDA) and hetero-Diels-Alder (HDA) cyclizations from an ambimodal transition st

135 ates in an intramolecular [4+2] hetero-Diels-Alder (IMDA) cyclization to furnish the bicyclo[2.2.2]di

136 selectivities from Alder-ene to hetero-Diels-Alder and vice versa.

137 idines and alkenes, and [4 + 2] hetero-Diels-Alder cycloaddition of aldehydes with dienes.

138 reaction proceeds via a tandem hetero-Diels-Alder cycloaddition of N,N'-bis(benzenesulfonyl)sulfur d

139 nctional end group, by means of hetero-Diels-Alder cycloaddition through their inherent terminal thio

140 pontaneous intramolecular [4+2] hetero-Diels-Alder cycloaddition.

141 -6pi electrocyclic ring-opening/hetero-Diels-Alder pericyclic cascade.

142 rea-catalyzed asymmetric direct hetero-Diels-Alder reaction between alkylidene azlactone-derived dien

143 This intramolecular hetero-Diels-Alder reaction features unactivated dienophiles and o-QM

144 The direct hetero-Diels-Alder reaction followed by ring opening results in dense

145 ene in metal-free base-assisted hetero-Diels-Alder reaction is exploited to quickly assemble an impor

146 Bronsted acid catalysts of the hetero-Diels-Alder reaction of a wide variety of aldehydes and dienes

147 sobruceol was an intramolecular hetero-Diels-Alder reaction of an o-quinone methide that was formed b

148 oselective, ytterbium-catalyzed hetero-Diels-Alder reaction of enones with vinyl ethers followed by a

149 ed by a highly stereocontrolled hetero-Diels-Alder reaction.

150 ond catalyses a stereoselective hetero-Diels-Alder reaction.

151 he asymmetric induction for the hetero-Diels-Alder reaction.

152 ed by two and three consecutive hetero-Diels-Alder reactions (or conjugated additions) between nitros

153 intramolecular Diels-Alder and hetero-Diels-Alder reactions via a single ambimodal transition state,

154 f alpha- and beta-lapachone via hetero-Diels-Alder reactions was investigated by experimental and com

155 The domino aldol/hetero-Diels-Alder synthesis of some new tricyclic pyrano[3,4-c]chrom

156 tandem inverse-electron-demand hetero-Diels-Alder/oxa-Michael reaction catalyzed by modularly design

157 ddition inverse-electron-demand hetero-Diels-Alder/retro-Diels-Alder ( ihDA/ rDA) reaction, was achie

158 troso compounds using a one-pot hetero-Diels-Alder/ring contraction sequence.

159 eps by capitalizing on the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction in which an int

160 periments showing that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction proceeds in a s

161 We demonstrate that the hexadehydro-Diels-Alder (HDDA) cycloisomerization reaction to produce reac

162 tes typically used for the hexadehydro-Diels-Alder (HDDA) cycloisomerization reactions that produce r

163 thermally generated by the hexadehydro-Diels-Alder (HDDA) cycloisomerization.

164 e we report the use of the hexadehydro-Diels-Alder (HDDA) reaction for the de novo construction of a

165 t benzynes produced by the hexadehydro-Diels-Alder (HDDA) reaction react with many secondary metaboli

166 triflate) and the thermal hexadehydro-Diels-Alder (HDDA) reaction.

167 ye reported intramolecular hexadehydro-Diels-Alder (HDDA) reactions to generate arynes that functiona

168 ts with the Rh-catalyzed stepwise homo Diels-Alder cyclisation of NBD into its exo-cis-endo dimer.

169 rophilic substitution and as dienes in Diels-Alder cycloaddition.

170 lly available arylsulfonyl cyanides in Diels-Alder cycloadditions to generate isopyridine cycloadduct

171 N-acyl iminium ions as dienophiles in Diels-Alder reactions and electrophilic alkylating agents are

172 their 1-aza- and 2-aza-derivatives in Diels-Alder reactions with ethylene and fumaronitrile were inv

173 The replacement of CH with N increases Diels-Alder reactivity due not only to the more favorable orbi

174 he various dienes for both the initial Diels-Alder reaction and a possible, subsequent ene reaction.

175 ane structures using an intermolecular Diels-Alder cycloaddition between a pyrazinone and commerciall

176 A stereoselective intermolecular Diels-Alder cycloaddition of an intermediate pyrazinone with b

177 undergo either in situ intermolecular Diels-Alder reactions to deliver highly functionalized/substit

178 emonstrated to catalyse intermolecular Diels-Alder transformations.

179 can undergo bifurcating intramolecular Diels-Alder (IMDA) and hetero-Diels-Alder (HDA) cyclizations f

180 highly stereoselective intramolecular Diels-Alder (IMDA) reaction of the camphanate-containing trien

181 cyclic transformations: intramolecular Diels-Alder and hetero-Diels-Alder reactions via a single ambi

182 ization cascade and the intramolecular Diels-Alder cascade.

183 mpleted by a late-stage intramolecular Diels-Alder furan (IMDAF) cycloaddition to install the indole.

184 An intramolecular Diels-Alder reaction and an enone-olefin cycloaddition/fragmen

185 An approach to the intramolecular Diels-Alder reaction has led to a cascade synthesis of complex

186 te-templated asymmetric intramolecular Diels-Alder reaction of a masked o-benzoquinone (MOB) 9 and an

187 chiral amine-catalyzed intramolecular Diels-Alder reaction to afford 22 in excellent diastereoselect

188 ty of parameters on the intramolecular Diels-Alder reaction was investigated, including diene and die

189 enzymatic examples (the intramolecular Diels-Alder reaction, and the Cope and the Claisen rearrangeme

190 taking advantage of an intramolecular Diels-Alder reaction, we have developed a prodrug strategy for

191 eading to a spontaneous intramolecular Diels-Alder reaction.

192 eral Lewis acid induced intramolecular Diels-Alder reactions remained fruitless, dialkylaluminum chlo

193 Nitrofurans undergo intramolecular Diels-Alder reactions with tethered electron-poor dienophiles

194 stributions of expected and isomerized Diels-Alder adducts.

195 wickerol A (1) that is based on a Jung Diels-Alder reaction, an intramolecular alkylation to complete

196 implicated in the formation of the key Diels-Alder substrate to give the spirocyclic system of the an

197 NH4OAc mediated domino Knoevenagel/Diels-Alder cyclocondensation of beta-ketosulfones 1 and o-for

198 s), and [4 + 2] cycloadditions (mainly Diels-Alder-type reactions).

199 emical activation of a furan-maleimide Diels-Alder adduct reveals a latent furfuryl carbonate that su

200 orthogonality, namely furan/maleimide Diels-Alder chemistry.

201 ecies which can be used to effect many Diels-Alder reactions in >95% yield and >95% ee using catalyst

202 key-step, a chiral auxiliary-mediated Diels-Alder cycloaddition was developed, introducing the three

203 ocatechol in inter- or intra-molecular Diels-Alder reactions.

204 loped, which depended on the extent of Diels-Alder (DA) reaction of bismaleimide with furan.

205 The mechanisms of Diels-Alder reactions between 1,2,3-triazines and enamines hav

206 Despite the importance of Diels-Alder reactions in the biosynthesis of numerous secondar

207 na, stabilizes and separates a pair of Diels-Alder reagents.

208 de an enantioselective organocatalytic Diels-Alder reaction to construct the C ring, a diastereoselec

209 , and enantioselective organocatalyzed Diels-Alder reactions with acrolein to form enantiomerically e

210 in analogues is derived via cross-over Diels-Alder reactions from pools of ortho-quinol precursors.

211 The method involves an initial oxa-Diels-Alder reaction of ortho-quinone methides generated from

212 esumably formed through an initial oxa-Diels-Alder reaction, followed by an elimination of amine.

213 eaturing an unprecedented oxopyrrolium Diels-Alder cycloaddition which furnishes a key tetracyclic in

214 cyclic reactions, including the parent Diels-Alder cycloaddition of butadiene with ethylene, electroc

215 loisomerization process a pentadehydro-Diels-Alder (PDDA) reaction-a nomenclature chosen for chemical

216 Specifically, we exploit the photo-Diels-Alder reaction of triazolinediones with naphthalenes as

217 hrough an intramolecular photochemical Diels-Alder reaction.

218 The key step consists of the one-pot Diels-Alder trapping of a reactive 2-aminofuran intermediate,

219 ones in unprotected form via a one-pot Diels-Alder/ring-opening/tautomerization sequence.

220 An intramolecular strain-promoted Diels-Alder methylenecyclopropane (IMDAMC) reaction provided a

221 e of oxidation of naphthazarin quinone Diels-Alder adduct 10 is additionally demonstrated and enables

222 diated [3,3]-sigmatropic rearrangement/Diels-Alder reaction of 1,9-dien-4-yne esters is described.

223 which the key step is a regioselective Diels-Alder reaction between a pyranobenzoquinone dienophile a

224 endo stereochemistry of the resulting Diels-Alder adduct, and confirmed that the unique architecture

225 ditions, these adducts undergo a retro Diels-Alder reaction and we use our temperature dependent NMR

226 ectron-demand hetero-Diels-Alder/retro-Diels-Alder ( ihDA/ rDA) reaction, was achieved using the high

227 d spontaneously decomposes via a retro-Diels-Alder (rDA) reaction to afford a beta-substituted furan/

228 l-molecule cargo was achieved by retro-Diels-Alder cleavage of an oxanorbornadiene linkage, presumabl

229 ion of bromo-ethylmalonate and a retro-Diels-Alder cycloaddition reaction.

230 (4) results in the corresponding retro-Diels-Alder reaction, establishing DPF as a molecule that is a

231 on the rate of force-accelerated retro-Diels-Alder reactions of furan/maleimide adducts.

232 oaddition with subsequent double retro-Diels-Alder reactions to form a stable pyrrole linkage.

233 ns occur, namely two Diels-Alder/retro-Diels-Alder sequences, which can be performed in a stepwise or

234 cess involves [4+2] Diels-Alder, retro-Diels-Alder, and 1-1' coupling reactions, and the former is th

235 ation, disulfide formation, reversible Diels-Alder reactions), and (iii) physical cross-linking (e.g.

236 Sequential Diels-Alder reactions on a tautomerized naphthazarin core were

237 Upon tandem Diels-Alder reactions with several symmetrical as well as unsy

238 1,3-dioxa-2-silacyclohexene templated Diels-Alder cycloaddition and type-3 semipinacol rearrangement

239 Here we demonstrate that Diels-Alder [4 + 2] cycloadditions can be harnessed for peptid

240 ly analyze the regioselectivity of the Diels-Alder (DA) reaction of cyclopentadiene to the hollow non

241 Manipulation of the Diels-Alder adducts provides the desired geometrically defined

242 sequent reductive deoxygenation of the Diels-Alder adducts with Fe2(CO)9 followed by oxidative aromat

243 h the gas phase, the enzyme lowers the Diels-Alder barrier significantly, consistent with experimenta

244 The Diels-Alder chemistry of these new dendralenes (as multidienes

245 Both are produced by the Diels-Alder condensation of hexachlorocyclopentadiene with cyc

246 g-closing metathesis reaction, and the Diels-Alder cycloaddition of a dienol acetate.

247 The key steps involve the Diels-Alder cycloaddition of cyclopent-2-en-1-one to the aceto

248 tric Lewis-acid organocatalysis of the Diels-Alder cycloaddition of cyclopentadiene to cinnamates ari

249 A case study of the Diels-Alder cycloaddition of cyclopentadiene with ethylene ser

250 To this end, the Diels-Alder cycloaddition reaction involving cyclopentadiene a

251 hyde motif that is inaccessible by the Diels-Alder cycloaddition.

252 oadduct under kinetic control, but the Diels-Alder cycloadduct is formed under thermodynamic control.

253 rd, the superoxide species reduces the Diels-Alder cycloadduct radical cation to the final product an

254 certain if any of them proceed via the Diels-Alder mechanism.

255 tly proposed mechanisms (including the Diels-Alder one) for this reaction in water (as a first-order

256 free energy simulations show that the Diels-Alder pathway is favored in the enzyme environment.

257 ditions, as an alternative path to the Diels-Alder products, are highly disfavored.

258 relation between the logarithms of the Diels-Alder rate constants and measured K(1:1) values.

259 ns are challenging to access using the Diels-Alder reaction (the ortho-para rule).

260 moiety of DPF is a potent diene in the Diels-Alder reaction and reacts with dienophiles dimethyl acet

261 The Diels-Alder reaction between 1 and 6 occurs under the selected

262 products with a dienophile through the Diels-Alder reaction confirmed the formation of vitamin D3 iso

263 The Diels-Alder reaction enables introduction of new functionaliti

264 The Diels-Alder reaction is a cornerstone of modern organic synthe

265 The Diels-Alder reaction is one of the most common methods to chem

266 The Diels-Alder reaction is one of the most powerful and widely us

267 nd 2,2,2-trifluoroacetophenone and the Diels-Alder reaction of cyclopentadiene with methyl vinyl keto

268 The Diels-Alder reaction of the photocaged diene (o-quinodimethane

269 It is observed that the Diels-Alder reaction only displays high diastereoselectivity w

270 e origins of chirality transfer in the Diels-Alder reaction using chiral arylallenes are uncovered, a

271 taining CPP precursor was used for the Diels-Alder reaction with the parent benzyne or 3,6-dimethoxyb

272 are attached to this module using the Diels-Alder reaction, which also forms one of the acene rings.

273 to the enhancement of the rate of the Diels-Alder reaction.

274 lents for application as dienes in the Diels-Alder reaction.

275 the distortion of the reactants in the Diels-Alder reactions are nearly identical and that the reacti

276 The Diels-Alder reactions between 2 equiv of (E,E)-1,4-bis(4-bromo

277 tivity and endo/exo selectivity of the Diels-Alder reactions involving 1,2-azaborines have been compu

278 Rolf Huisgen explored the Diels-Alder reactions of 1,3,5-cycloheptatriene (CHT) and cycl

279 The Diels-Alder reactions of 2-(1'-cycloalkenyl)thiophenes and 2-(

280 The activation free energies for the Diels-Alder reactions of cyclic 1-azadienes are 10-14 kcal mol

281 ivities and stereoselectivities in the Diels-Alder reactions of substituted cyclopropenes with butadi

282 The Diels-Alder reactivities of a series of cycloalkenes, from the

283 The physical factors governing the Diels-Alder reactivity of (2,7)pyrenophanes have been computat

284 The Diels-Alder reactivity of C59NH azafullerene has been explored

285 The Diels-Alder substrate is built up in an efficient manner by rh

286 Thermal Diels-Alder reactions of alpha-amido acrylates with N-Cbz-1,2-

287 ers undergo a Michael-type addition to Diels-Alder (DA) adducts of furylated drugs and acetylenedicar

288 f spinosyn A, catalyzes a transannular Diels-Alder reaction.

289 te for a successful diene transmissive Diels-Alder (DTDA) reaction by employing two different dienoph

290 reparative value of diene-transmissive Diels-Alder sequences since they offer products of regio- and

291 t the temperature dependent NMR of two Diels-Alder adducts of furan: one formed with maleic anhydride

292 mycinone were achieved by means of two Diels-Alder reactions.

293 pericyclic reactions occur, namely two Diels-Alder/retro-Diels-Alder sequences, which can be performe

294 ible from benzocyclobutenol, undergoes Diels-Alder reaction with vinylphosphine oxides, yielding the

295 Aromatics are formed via Diels-Alder cycloaddition with ethylene, which is produced in

296 enzymes that reverse periselectivities from Alder-ene to hetero-Diels-Alder and vice versa.

297 The key steps are an intramolecular Alder-ene (IMAE) reaction and a lactam-to-lactone rearra

298 cted to a palladium-catalyzed intramolecular Alder-ene (IMAE) reaction, thus producing the isomeric a

299 t-catalyzed hydrovinylation reaction and the Alder-ene reaction generate acyclic 1,4-dienes, which we

300 best match is for an age of 1.186 Ma for the Alder Creek Rhyolite sanidine and 28.201 Ma for the Fish