ライフサイエンスコーパス: Alternaria

1 ses and eosinophilia induced by the allergen Alternaria.

2 mice were challenged once intranasally with Alternaria.

3 es, attenuated the eosinophils' responses to Alternaria.

4 ype 2 airway inflammation in mice exposed to Alternaria.

5 ytokine secretion in vivo in mice exposed to Alternaria.

6 ere Cladosporium, Fusarium, Aspergillus, and Alternaria.

7 function and airway eosinophilia induced by Alternaria.

8 o protease-containing aeroallergens, such as Alternaria.

9 Exposure to Alternaria (adjusted odds ratio [aOR], 1.07; 95% CI, 1.0

10 Alternaria aeroallergens induce the release of ATP from

11 id cell (ILC2) and eosinophilic responses to Alternaria allergen administration, and diminished eosin

12 )Rag2(-/-) mice exposed to asthma-associated Alternaria allergen develop enhanced eosinophilic lung i

13 Repetitive exposure of Rag1-/- mice to the Alternaria allergen extract generated a form of memory t

14 yperresponsiveness in a mouse model of acute Alternaria allergen inhalation.

15 Previously, Alternaria allergens were shown to produce a sustained i

16 PBMCs from Alternaria-allergic donors were stimulated with Alt a 1

17 In a therapeutic mouse model of Alternaria allergy nasal application of holo-Alt a 1, bu

18 improving allergen-specific immunotherapy in Alternaria allergy.

19 Alternaria also strongly induced other activation events

20 plantain Pla l 1), three were mold allergen (Alternaria Alt a 1), and a single one regards house dust

21 d were highest for Candida albicans (18.6%), Alternaria alternata (16.6%), Stemphylium herbarum (14.9

22 AC with Dermatophagoides pteronyssinus (DP), Alternaria alternata (AA), grass (GP) and olive (OP) pol

23 nut extract (PNE), an environmental allergen Alternaria alternata (Alt) and a detergent induce food a

24 ut extract (PNE), the environmental allergen Alternaria alternata (Alt), and detergent (4% SDS); oral

25 /musty odour and increased concentrations of Alternaria alternata allergen, Aspergillus fumigatus ant

26 associated mold sensitivity, particularly to Alternaria alternata and Cladosporium herbarum, with the

27 Alternaria alternata and house dust mite exposure evokes

28 e, and allergens that activate GPCRs such as Alternaria alternata and house dust mite.

29 ungal LOV-domain blue-light receptor LreA of Alternaria alternata and show that it predominantly cont

30 tory treatment and frequent sensitization to Alternaria alternata and soybean.

31 ls of Streptococcus pneumoniae infection and Alternaria alternata asthma, we show that sensory neuron

32 ve fungus] [clinical syndrome], for example, Alternaria alternata cutaneous infection.

33 ies identifying proteins from fungal species Alternaria alternata due to significant interspecies pro

34 ure to extract from the respiratory pathogen Alternaria alternata elicits profound epithelial cell (E

35 rmal and asthmatic subjects to extracts from Alternaria alternata evoked a rapid and sustained releas

36 bese) mice were challenged intranasally with Alternaria alternata extract (Alt-Ext) or PBS for 4 cons

37 (-/-) mice were challenged intranasally with Alternaria alternata extract for 4 consecutive days to i

38 ive mice were intranasally exposed to fungus Alternaria alternata extract or house dust mite for up t

39 ated lung inflammation following exposure to Alternaria alternata extract, marked by increased IL-5 a

40 House dust mite extract, Alternaria alternata extract, or rIL-33 was used to indu

41 by using IL-33, house dust mite extract, or Alternaria alternata extract.

42 linking apoptosis to this disease caused by Alternaria alternata f. sp. lycopersici.

43 Alternaria alternata f.sp. Lycopersici (AAL) toxin induc

44 sed in the mouse models of IL-33, IL-25, and Alternaria alternata ILC2-dependent airway inflammation.

45 and secretion in the phytopathogenic fungus Alternaria alternata in the presence of host-plant extra

46 Alternaria alternata is a clinically relevant allergen t

47 Direct exposure to the fungal species Alternaria alternata is a major risk factor for the deve

48 Alternaria alternata is associated with allergic respira

49 The fungal allergen Alternaria alternata is implicated in severe asthma and

50 Fusarium moniliforme toxins (fumonisins) and Alternaria alternata lycopersici (AAL) toxins are member

51 ic utility of MIS416 was investigated in the Alternaria alternata model of allergic asthma and in hum

52 exacerbated ILC2-dependent AHR in IL-33 and Alternaria alternata models.

53 y, we studied the effect of IL-33trap in the Alternaria alternata mouse model of allergic airway infl

54 mice were subjected to acute challenge with Alternaria alternata or house dust mite, and secretion o

55 long with 11 known compounds from the fungus Alternaria alternata P1210.

56 We found that Alternaria alternata produces aspartate protease(s) and

57 The tangerine pathotype of Alternaria alternata produces the A. citri toxin (ACT) a

58 derived from the common saprophytic fungus, Alternaria alternata release ATP, which in turn stimulat

59 ulated pomegranate fruits with six different Alternaria alternata species complex isolates, known to

60 ecretion of mannitol in the tobacco pathogen Alternaria alternata suggested that, like their animal c

61 ere repeatedly exposed to house dust mite or Alternaria alternata three times a week for up to 5 week

62 ponses after exposure to the fungal allergen Alternaria alternata Thus, CysLT1R promotes LTC4- and Al

63 nst Phytophthora parasitica var. nicotianae, Alternaria alternata var. nicotianae and Rhizoctonia sol

64 c airways disease to the fungal aeroallergen Alternaria alternata was determined.

65 in the presence or absence of VCs emitted by Alternaria alternata We found that volatile emissions fr

66 iveness to cold dry air and sensitisation to Alternaria alternata were determined before age 6 years.

67 hibition in growth of Rhizoctonia solani and Alternaria alternata were observed in response to ZNsw.

68 gic airway inflammation (house dust mice and Alternaria alternata) and OVA-induced models of active a

69 trinum, Aspergillus flavus, Fusarium solani, Alternaria alternata, Alternaria citri, Pseudomonas syri

70 d, timothy grass, ash tree, mites, dog, cat, Alternaria alternata, and Fagales mix).

71 ally challenged with PBS or mixed allergen ( Alternaria alternata, Aspergillus fumigatus, house dust

72 cts from seven environmental airborne fungi (Alternaria alternata, Aspergillus versicolor, Bipolaris

73 d, and specific IgE levels were measured for Alternaria alternata, cat, cockroach, dog, Dermatophagoi

74 whole extract fungal (Aspergillus fumigatus, Alternaria alternata, Cryptococcus neoformans and Candid

75 s farinae, dog, cat, timothy grass, ragweed, Alternaria alternata, egg, peanut, milk, and German cock

76 nically relevant ubiquitous fungal allergen, Alternaria alternata, increases bronchoalveolar lavage l

77 ommon environmental aeroallergen, the fungus Alternaria alternata, induces rapid release of IL-33 int

78 rotease-containing fungal allergens, such as Alternaria alternata, is not fully defined.

79 ichia coli or the fungi Botrytis cinerea and Alternaria alternata, likely due to limited ZnO release

80 (NAPT) with Dermatophagoides pteronyssinus, Alternaria alternata, Olea europaea and grass pollen wer

81 n tests with Dermatophagoides pteronyssinus, Alternaria alternata, Olea europea, and a mix of grass p

82 esponse positivity to Aspergillus fumigatus, Alternaria alternata, or Cladosporium herbarum.

83 oallergens, such as house dust mite (HDM) or Alternaria alternata, to induce experimental asthma.

84 vigorously to a common environmental fungus, Alternaria alternata, which is implicated in the develop

85 skin infection with phaeohyphomycosis due to Alternaria alternata, which we treated with topical anti

86 TrkA inhibition in Alternaria alternata-challenged TrkA-KI mice markedly in

87 ameliorates ILC2-dependent AHR in IL-33 and Alternaria alternata-induced models.

88 on of house dust mite or the fungal allergen Alternaria alternata.

89 on the major allergen Alt a 1 of the fungus Alternaria alternata.

90 goides pteronyssinus) or the fungal allergen Alternaria alternata.

91 inflammation induced by the fungal allergen Alternaria alternata.

92 asally on days 0, 3 and 6 with a filtrate of Alternaria alternata.

93 ys were exposed to a common fungal allergen, Alternaria alternata.

94 for pathogenicity in the necrotrophic fungus Alternaria alternata.

95 sal administration of mouse genomic DNA with Alternaria amplified secretion of IL-5 and IL-13 into br

96 tion by age 12, in response to environmental Alternaria and Aspergillus, was elevated in children wit

97 an rhinovirus infection and sensitization to Alternaria and Cladosporium and daily counts of ambient

98 tigated the roles of protease(s) produced by Alternaria and of PARs expressed on eosinophils in their

99 Alternaria and Penicillium induced calcium-dependent exo

100 ts mites, pollens, animal epithelia, moulds (alternaria) and others.

101 ne allergens, including the house dust mite, Alternaria, and Aspergillus, for up to 8 wk.

102 exposure to an environmental fungus, such as Alternaria, and asthma have been recognized clinically.

103 een exposure to environmental fungi, such as Alternaria, and development and/or exacerbation of asthm

104 ing Dermatophagoides pteronyssinus, pollens, alternaria, and dog epithelia, was performed in patients

105 iven inhaled house dust mite, cat dander, or Alternaria, and the effect of inhibiting allergen-specif

106 Except for Alternaria antigen in dust, concentrations of airborne m

107 Alternaria antigen was detected in dust from 98% of home

108 aeroallergen (house dust mite, cockroach, or Alternaria antigen) or virus exposure induced the nuclea

109 Although Alternaria, Arthrinium, Epicoccum and Curvularia were si

110 mechanisms of airway Th2 responses by using Alternaria as a clinically relevant model for environmen

111 The presence of Cladosporium, Alternaria, Aspergillus, and Penicillium species increas

112 Cladosporium, Alternaria, Aspergillus, and Penicillium species were fo

113 ight into the uniquely pathogenic aspects of Alternaria-associated asthma.

114 ally on skin test reactivity to the allergen Alternaria at age 6 from among a large population of chi

115 ely to the abundance of most taxa, including Alternaria, Aureobasidium, Pseudopithomyces, Pseudomonas

116 erence in detection rate or concentration of Alternaria between asthmatic homes and homes without an

117 such as sclerotinia stem rot, blackleg, and alternaria black spot resulting in significant loss of c

118 ant contribution of redox-mediated pathways, Alternaria blight continues to infect crops in the Brass

119 d associated signaling networks triggered by Alternaria blight.

120 5 conferred transgenic apple plants enhanced Alternaria blotch resistance.

121 light (ALB), caused by a necrotrophic fungus Alternaria brassicae is a serious disease of oleiferous

122 ression conferred greater protection against Alternaria brassicae, Leptosphaeria maculans and Sclerot

123 transmission of two phytopathogenic agents, Alternaria brassicicola Abra43 (Abra43) and Xanthomonas

124 al plant pathogens (namely Botrytis cinerea, Alternaria brassicicola and Golovinomyces orontii).

125 resistance of gai to the necrotrophic fungus Alternaria brassicicola and susceptibility to the hemibi

126 immune responses to the necrotrophic fungus Alternaria brassicicola and the bacterial hemibiotroph P

127 the necrotrophic fungi Botrytis cinerea and Alternaria brassicicola as well as the generalist herbiv

128 necrotrophic fungal pathogens B. cinerea and Alternaria brassicicola based on increased pathogen grow

129 ore susceptible to the necrotrophic pathogen Alternaria brassicicola by suppression of the JA signali

130 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola concomitant with reduced express

131 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola in the Nossen-0 background but h

132 Alternaria brassicicola is a successful saprophyte and n

133 Alternaria brassicicola is an important, necrotrophic fu

134 gae pv tomato DC3000 and the fungal pathogen Alternaria brassicicola, although these phenotypes were

135 HDA19 was induced by wounding, the pathogen Alternaria brassicicola, and the plant hormones jasmonic

136 utants also show increased susceptibility to Alternaria brassicicola, another necrotrophic pathogen,

137 lly important necrotrophic fungi B. cinerea, Alternaria brassicicola, Fusarium graminearum, and Scler

138 arum, and the Arabidopsis thaliana pathogen, Alternaria brassicicola, resulted in reduced virulence a

139 the spread of another necrotrophic pathogen, Alternaria brassicicola, suggesting a common host respon

140 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola, whereas HUB1 overexpression con

141 ed susceptibility to the necrotrophic fungus Alternaria brassicicola.

142 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola.

143 ific susceptibility to the fungal necrotroph Alternaria brassicicola.

144 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola.

145 o desiccation and to infection by the fungus Alternaria brassicicola.

146 nfection by the necrotrophic fungal pathogen Alternaria brassicicola.

147 idopsis are resistant to the fungal pathogen Alternaria brassicicola.

148 e dipteran Bradysia impatiens and the fungus Alternaria brassicicola.

149 ompromises resistance to the fungal pathogen Alternaria brassicicola.

150 he defense against the necrotrophic pathogen Alternaria brassicicola.

151 to brassicicolin A, a known isocyanide from Alternaria brassicicola.

152 rophic fungal pathogens Botrytis cinerea and Alternaria brassicicola.

153 to the pathogenic fungi Botrytis cinerea and Alternaria brassisicola Both PAMPs and osmotic stress ac

154 mold strains of the genera Cladosporium and Alternaria but none on bacteria.

155 Alternaria, but not other common aeroallergens, possesse

156 Skin testing was performed for Alternaria, cat, cockroach, dog, Dermatophagoides farina

157 After a single airway exposure to OVA with Alternaria, CD69(+)ST2(+) T(H)2-type T cells, which high

158 Intranasal administration of Alternaria challenge reduced ILC2 numbers in the bone ma

159 Z1 expression as early as 3 h after a single Alternaria challenge that persisted for >/=5 d and was s

160 ronchoalveolar lavage eosinophilia following Alternaria challenge when analyzed 24 h later.

161 IL-33 in bronchoalveolar lavage fluid after Alternaria challenge, suggesting that more IL-33 was ava

162 epithelial cell brushings demonstrated that Alternaria-challenged naive WT mice had a >20-fold incre

163 avus, Fusarium solani, Alternaria alternata, Alternaria citri, Pseudomonas syringae, Elsinoe fawcetti

164 ble levels of common aeroallergens including Alternaria, cockroach, dog, dust mite, cat, mouse, and r

165 Alternaria concentration was associated with any wheeze

166 Whereas in some cases (e.g., orchard grass, Alternaria, cypress, and Russian thistle) IL-5 productio

167 Alternaria-derived aspartate protease(s) cleaved PAR-2 t

168 did not induce eosinophil degranulation, and Alternaria did not induce neutrophil activation, suggest

169 black roots, symptoms similar to a Fusarium-Alternaria disease complex, recently characterized in a

170 duction by activated DCs, and DCs exposed to Alternaria enhanced Th2 polarization of CD4(+) T cells.

171 d the growth of all competing fungi, such as Alternaria, Epicoccum and Ulocladium species.

172 Alternaria-evoked ATP release exhibited a greater peak r

173 of the channel by RNA interference, inhibit Alternaria-evoked ATP release.

174 Inhibition of VDAC-1 blocked Alternaria-evoked Ca(2+) uptake across the plasma membra

175 ease in [Ca2+]i typically observed following Alternaria exposure appeared to be independent of protea

176 grate from the circulation to the lung after Alternaria exposure is unknown.

177 meability that was previously observed after Alternaria exposure.

178 l subsets were identified in the lungs after Alternaria exposure.

179 omolecule permeability that occurs following Alternaria exposure.

180 lungs showed robust expression of IL-5 after Alternaria exposure.

181 d IL33(fl/fl) eGFP mice were challenged with Alternaria extract (Alt Ext) or vehicle for 4 days.

182 /-) ) mice were challenged intranasally with Alternaria extract (Alt-Ext) or PBS for 4 consecutive da

183 ung lavage samples from mice challenged with Alternaria extract and in sputum from patients with mode

184 intranasally to ovalbumin (OVA) antigen with Alternaria extract as an adjuvant.

185 or vehicle and challenged intranasally with Alternaria extract for four consecutive days to induce i

186 Alternaria extract rapidly induces mitochondrial and nuc

187 A proximity ligand assay showed that Alternaria extract stimulated MARCKS desorption from the

188 Exposure of hBE cells to Alternaria extract stimulated P2Y(2) receptors coupled t

189 The eosinophil-stimulating activity in Alternaria extract was highly heat labile and had an M(r

190 Finally, treatment of Alternaria extract with aspartate protease inhibitors, w

191 n bronchial epithelial cells were exposed to Alternaria extract, TSLP was potently induced.

192 ) and the PGI(2) analogs cicaprost decreased Alternaria extract-induced IL-33 release by human bronch

193 us administration of a PGI2 analog inhibited Alternaria extract-induced lung IL-5 and IL-13 protein e

194 were exposed to these Ags in the presence of Alternaria extract.

195 lly with pharmacologic agents and exposed to Alternaria extract.

196 were examined in Balb/c mice challenged with Alternaria extracts, with or without treatment with JQ1.

197 of these integrins before airway exposure to Alternaria in mice.

198 tment repressed ILC2 activity and suppressed Alternaria-induced airway inflammation and AHR.

199 IL-33 release and Th2-type responses in the Alternaria-induced airway inflammation model in naive mi

200 lts indicate that an important mechanism for Alternaria-induced ATP release is Ca2+ dependent and inv

201 as the conductive mechanism responsible for Alternaria-induced ATP release, an essential early step

202 nd cysteine protease inhibitors also reduced Alternaria-induced ATP release; however, the sustained i

203 In caspase-3-deficient mice, Alternaria-induced DNA release was suppressed.

204 The Alternaria-induced eosinophil degranulation was pertussi

205 a alternata Thus, CysLT1R promotes LTC4- and Alternaria-induced ILC2 activation and lung inflammation

206 OX pathway on ILC2 function is inhibitory in Alternaria-induced innate airway inflammation.

207 in models of dry skin or compound 48/80- or Alternaria-induced itch.

208 the hypothesis that COX inhibition augments Alternaria-induced pulmonary group 2 innate lymphoid cel

209 In mice, Alternaria-induced type 2 immune responses were blocked

210 Thus, Alternaria induces STAT6-dependent acute airway eosinoph

211 In response to Alternaria infection, additional reactive oxygen species

212 lung inflammation in response to repetitive Alternaria inhalation challenges.

213 Importantly, Alternaria inhibited IL-12 production by activated DCs,

214 Alternaria is a potent inducer of cellular stress and th

215 We conclude that Alternaria is the major allergen associated with the dev

216 posure to ubiquitous airborne fungi, such as Alternaria, is implicated in the development and exacerb

217 The fungal allergen, Alternaria, is specifically associated with severe asthm

218 Alternaria leaf blight (ALB), caused by a necrotrophic f

219 significant lagged effects up to 3 days with Alternaria, Leptosphaeria, Cladosporium, Sporormiella, C

220 Early blight (EB) caused by Alternaria linariae or Alternaria solani and leaf blight

221 Alternaria linariae populations harboured more multilocu

222 te (Der p 1), cockroach (Bla g 1), and mold (Alternaria mix) allergens using ELISA.

223 ytical method for the determination of three Alternaria mycotoxins (alternariol, alternariol monometh

224 Occurrence of type A trichothecenes, Alternaria mycotoxins and their conjugates in the final

225 used for the routine monitoring of the major Alternaria mycotoxins in pomegranates.

226 The stability of two Alternaria mycotoxins, alternariol (AOH) and alternariol

227 ted porous polymer microspheres selective to Alternaria mycotoxins, alternariol (AOH) and alternariol

228 derstand the acute innate airway response to Alternaria, naive wild-type (WT) mice were challenged on

229 Inheritance patterns for Alternaria-negative asthma revealed a contribution from

230 ildren at age 6 into Alternaria-positive and Alternaria-negative groups identifies subphenotypes that

231 g Alternaria-positive subjects, asthma among Alternaria-negative subjects was associated with lower l

232 In contrast to Alternaria, neither Aspergillus nor Candida induced bron

233 were positively associated with indoor dust Alternaria [odds ratio (OR) = 1.83; 95% confidence inter

234 m EpC mucin release and swelling elicited by Alternaria or by intranasal LTE4 GPR99 expression is det

235 that human eosinophils respond vigorously to Alternaria organisms and to the secretory product(s) of

236 cies of the Capnodiales group, including the Alternaria pathogen, on aromatic compounds.

237 sts and sterile mycelium, were Cladosporium, Alternaria, Penicillium, Ulocadium, Fusarium, Arthrinium

238 s, dividing asthma in children at age 6 into Alternaria-positive and Alternaria-negative groups ident

239 ontributed approximately equivalent risk for Alternaria-positive asthma in the child.

240 When compared with asthma among Alternaria-positive subjects, asthma among Alternaria-ne

241 hus, the asthma-related environmental fungus Alternaria produces potent Th2-like adjuvant effects in

242 ation machinery that directly responds to an Alternaria protein product(s).

243 sensitized and challenged with ovalbumin or Alternaria received OM-85 intranasally, and cardinal cel

244 ty to utilize sole carbon sources suggesting Alternaria regulates expression of cell wall-degrading e

245 Zygomycetes (RR = 1.96; CI, 1.35, 2.83), and Alternaria (RR = 1.51; CI, 1.00, 2.28), after controllin

246 Furthermore, this Alternaria serine protease-IL-33 axis triggered a rapid,

247 , including Colletotrichum and Fusarium, and Alternaria, sharply increased at harvest stage, likely c

248 previously exposed intranasally to OVA with Alternaria showed more robust antigen-specific immune re

249 had been pulsed with OVA in the presence of Alternaria, showed that the recipient mice had enhanced

250 (diagnosed after age 6) was associated with Alternaria skin tests at age 6 but not at age 11.

251 ore age 6) was independently associated with Alternaria skin tests at both ages 6 and 11, whereas new

252 blight (EB) caused by Alternaria linariae or Alternaria solani and leaf blight (LB) caused by A. alte

253 onferred tolerance to salt stress and fungus Alternaria solani infection.

254 Alternaria solani severely affects tomato (Solanum lycop

255 hird crucial global crop facing threats from Alternaria solani, a necrotrophic fungal pathogen causin

256 the fungal necrotrophs Botrytis cinerea and Alternaria solani, bacterial pathogen Pseudomonas syring

257 ly blight, caused by the necrotrophic fungus Alternaria solani, is an increasing problem in potato cu

258 with or without infection with necrotrophic Alternaria solani, though no adverse effect could be obs

259 thium irregulare, Fusarium oxysporum solani, Alternaria solani, Trichoderma reesei, and Trichoderma h

260 ces against the necrotrophic fungal pathogen Alternaria solani.

261 luding Aspergillus sp., Penicillium sp., and Alternaria sp. Hydrophobic Deep Eutectic Solvents (HDESs

262 luding Aspergillus sp., Penicillium sp., and Alternaria sp. Matrix effect (ME) is unavoidable in mult

263 al pathogens, Fusarium brachygibbosum U4 and Alternaria sp. U10, and the specialist herbivore Manduca

264 corymbifera, Aspergillus sp. (five species), Alternaria sp., Bipolaris spicifera, Fusarium sp. (three

265 is of the mycobiota showed a predominance of Alternaria sp., Fusarium sp. and Epicoccum sp. Microdoch

266 Alternaria species are widespread microfungi the seconda

267 Alternaria species is one of the most common molds assoc

268 Finally, LTD(4) was coadministered with Alternaria species repetitively to RAG2(-/-) mice (with

269 Penicillium, Aspergillus, Cladosporium, and Alternaria species, although further work should conside

270 ld-type, RAG2(-/-), and STAT6(-/-) naive and Alternaria species-challenged mice.

271 Additionally, LTD(4) potentiates Alternaria species-induced eosinophilia and ILC2 prolife

272 Finally, LTD(4) potentiated Alternaria species-induced eosinophilia, as well as ILC2

273 rected toward new forms of immunotherapy for Alternaria species-sensitive allergic patients.

274 ssociated with allergic diseases, and 80% of Alternaria species-sensitive patients produce IgE antibo

275 Alternaria-specific serine protease activity causes rapi

276 genetic clusters corresponding to the three Alternaria spp.

277 insights into the evolution and structure of Alternaria spp. and can lead to new directions in optimi

278 AAL-toxin is the primary determinant of the Alternaria stem canker disease of tomato, thus linking a

279 Alternaria stimulated bone marrow-derived dendritic cell

280 r cholesterol lowering compounds in reducing Alternaria-stimulated allergic inflammation.

281 efeldin A and BAPTA-AM significantly blocked Alternaria-stimulated incorporation of fluorescent lipid

282 are present in mouse lung and are induced by Alternaria, suggesting commonly used ILC2 identification

283 persensitive to grass pollen, cat dander and Alternaria tenuis with a history of urticaria and dyspno

284 muli, including innate stimuli (TLR ligands, Alternaria), Th2 cytokines (IL-4, IL-13), and adaptive i

285 ellular calcium concentration in response to Alternaria that was desensitized by peptide and protease

286 The unique capacity of Alternaria to drive this early IL-33 release resulted in

287 Besides the zearalenone group, the Alternaria toxin alternariol (AOH) has been described as

288 to sauces) resulted positive to at least one alternaria toxin investigated.

289 toxin (TEN), and tenuazonic acid (TeA), five alternaria toxins (ATs) was developed by liquid chromato

290 rst report about possibility of reduction of Alternaria toxins in wheat using the extrusion process.

291 However, the estrogenicity of Alternaria toxins is still largely overlooked and furthe

292 ptimal parameters for reduction of all three Alternaria toxins were as follows: w=24g/100g, q=25kg/h,

293 e maximum increase in [Ca2+]i resulting from Alternaria treatment was greater in cells from asthmatic

294 re associated with more common rhinitis, and Alternaria was associated with asthma.

295 sought to investigate the mechanism whereby Alternaria was capable of initiating severe, rapid onset

296 Although Alternaria was commonly found in both kinds of homes, th

297 The TSLP-inducing activity of Alternaria was partially blocked by treating the extract

298 By logistic regression, Alternaria was the only allergen independently associate

299 organisms and to the secretory product(s) of Alternaria with eosinophils releasing their proinflammat

300 te before subsequently being challenged with Alternaria (with or without serine protease activity), a