コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 asting, high-avidity Ab response against the B cell epitope.
2 aining a single amino acid substitution in a B cell epitope.
3 antibody to a second, independent native ZP3 B cell epitope.
4 es as the carrier for a defined heterologous B cell epitope.
5 (isoleucine) were implicated in a pathogenic B cell epitope.
6 clonal antibody that targets a protective Ft B cell epitope.
7 d particle is known to contain a predominant B-cell epitope.
8 minal sugar of the Ogawa LPS is a protective B-cell epitope.
9 SARS-CoV-2 and identify putative T cell and B cell epitopes.
10 4(+) T cell epitopes as well as CD8(+) T and B cell epitopes.
11 ogenic autoantibodies gain access to cryptic B cell epitopes.
12 mily, resulting in the expression of variant B cell epitopes.
13 ecule contains important CD8(+), CD4(+), and B cell epitopes.
14 tional structures and carbohydrate chains to B cell epitopes.
15 a novel BLAST-based method to predict linear B cell epitopes.
16 g state-of-the-art methods to predict linear B cell epitopes.
17 e, are known or expected to contain multiple B cell epitopes.
18 s to large-protein Ags that display numerous B cell epitopes.
19 elper epitopes genetically linked to defined B cell epitopes.
20 y in regions corresponding to defined linear B-cell epitopes.
21 vaccine carrier platforms for heterologous, B-cell epitopes.
22 These areas are commonly dubbed B-cell epitopes.
23 falciparum will need to contain both T- and B-cell epitopes.
24 at positions 44 to 63) contained both T- and B-cell epitopes.
25 the recombinant antigen contained T-cell and B-cell epitopes.
26 entral hypervariable region encoding variant B-cell epitopes.
27 the presence of immunogenic conserved linear B-cell epitopes.
28 RAP-1 homolog did not contain cross-reactive B-cell epitopes.
29 y distinct MSP-2 molecules which bear unique B-cell epitopes.
30 nces (VS1 to VS4) harboring serovar-specific B-cell epitopes.
31 rly for the identification of conformational B-cell epitopes.
32 , with potential positive selection sites on B-cell epitopes.
33 ediction tools were used to identify LASV GP B-cell epitopes.
34 ggested the presence of conserved and unique B-cell epitopes.
35 fold to present conformationally constrained B-cell epitopes.
36 ant immunotoxins by identifying and removing B-cell epitopes.
37 immunodominant HLA class I, HLA class II and B- cell epitopes.
38 only low levels of antibodies to inhibitory B-cell epitope 1 (iB-1), an inhibitory epitope in RAP-1(
39 a vaccine candidate with 13 highly antigenic B-cell epitopes, 19 HTL antigenic epitopes, and 18 CTL e
42 posed vaccine is armed with 6-16 mers linear B-cell epitopes, 4-9 mer CTL epitopes, and 8-15 mer HTL
43 a 694aa multi-epitope vaccine containing 16 B-cell epitopes, 82 CTL epitopes and 89 HTL epitopes, wh
44 ell determinant associated with a 12-residue B cell epitope, a process termed somatic transgene immun
45 nses against foreign antigens, we tested two B-cell epitopes: a novel neutralizing B-cell epitope, de
46 Active immunotherapy with conformational B cell epitopes affords the possibility of generating an
47 taining only B-tail-C3dg and lacking the TNF B cell epitope also showed improvements in both models,
49 t the same polymorphism may control both the B cell epitope and constitute the MHC-bound peptide, we
50 anched core with a peptide module containing B cell epitopes and a universal T cell epitope of the Pl
51 esponse is triggered by recognition of T and B cell epitopes and is influenced by "danger" motifs tha
52 asizing the significance of virion-dependent B cell epitopes and the limitations of envelope protein-
53 acid repeats that comprise a surface-exposed B-cell epitope and (ii) the presence of a 32-amino-acid
54 es in surface electrostatic potential of HLA B-cell epitopes and applied this to explain HLA Bw4 and
55 identified in this study are immunodominant B-cell epitopes and may represent good candidates for se
57 sed to predict the presence of discontinuous B-cell epitopes and to confirm the molecular binding sta
58 One such polymorphic locus formed part of a B cell epitope, and antibodies from exposed individuals
59 ents to determine B cell domain specificity, B cell epitopes, and the relative importance of linear a
60 cific modelling for the prediction of linear B-cell epitopes, and the challenges faced when building
62 B cell epitope sequences and considered as a B cell epitope any peptide sequence producing ungapped B
63 ural pan DR epitope (PADRE) and carbohydrate B cell epitopes are demonstrated to be potent immunogens
68 y synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunoge
69 pilin glycan, was found to be a major linear B-cell epitope, as determined by peptide epitope mapping
71 a prime vaccine candidate, but variation in B-cell epitopes at the dimer interface of DBP leads to i
72 imeric RHDV VLPs by insertion of the foreign B-cell epitopes at three different locations within VP60
73 59R), Tau (AV-1980R) or Abeta/tau (AV-1953R) B cell epitopes, based on immunogenic MultiTEP platform
75 ide biosynthetic approach, 30 precise linear B-cell epitopes (BCEs) were mapped on E6, E7 and L1 prot
76 e demonstrate that short 7-12-aa peptides of B-cell epitopes bind antibodies poorly; thus, epitope ma
77 e (same T cell epitopes) and structure (same B cell epitopes) but with different susceptibilities to
79 t a peptide vaccine containing minimal T and B cell epitopes composed of only 5 amino acids (N, A, V,
80 e surface as well as rhoptries and expresses B-cell epitopes conserved among otherwise antigenically
82 ecies specific and identified three distinct B-cell epitopes containing sequences DRYI, CHPSDGKC, and
85 -epitopes, are over-represented in published B-cell epitope datasets that are commonly used for devel
87 red binding kinetics identified "functional" B-cell epitopes, defined as those residues contributing
88 humoral responses against displayed foreign B-cell epitopes, demonstrated by both, in vitro neutrali
89 d an Ad-based malaria vaccine by inserting a B cell epitope derived from a Plasmodium yoelii circumsp
90 were genetically fused to an immunodominant B cell epitope derived from the N-terminal region I and
91 d a lipopeptide oral delivery system using a B-cell epitope derived from the aspartic protease Na-APR
92 profile, and immunogenicity of two chimeric, B-cell epitopes derived from the human epidermal growth
93 ed two B-cell epitopes: a novel neutralizing B-cell epitope, derived from feline calicivirus capsid p
95 uently boosted with molecules containing the B cell epitope-derived peptide without carrier or linked
96 pCol(28-40); that is, 1) elimination of the B cell epitope, either by substitution of the critical r
98 ent malaria models have shown that CS repeat B-cell epitopes expressed in a recombinant hepatitis B v
100 1, a novel conjugate of Abeta1-15 peptide (a B-cell epitope fragment) conjugated to an immunogenic ca
101 The B cell component consists of just 3 B cell epitopes from the ectodomain of glycoproteins L a
102 eptide system containing B-tail-tagged C3dg, B cell epitopes from TNF, and the universal T cell epito
104 enovirus 5 (Ad5) recombinant that displays a B-cell epitope from the circumsporozoite protein (CSP) o
105 MAP (T3-CS-T1) containing T3-T1 and a potent B-cell epitope from the circumsporozoite protein central
106 rus capsid protein, and a well characterized B-cell epitope from the extracellular domain of influenz
108 date, termed ICC-1132, which contains T- and B-cell epitopes from the repeat region and a universal T
109 sis for the cryptic nature (crypticity) of a B cell epitope harbored by an autoantigen is unknown.
111 ubsequent transfusion with RBCs expressing a B-cell epitope (hen egg lysozyme [HEL]) fused to (OVA)(3
112 een mounted an antibody response against the B-cell epitope higher than mice receiving the gene codin
113 oligomannose glycans on Env shields peptidic B cell epitopes, impedes the presentation of T helper ce
115 Second, B cells specific to the peptidic B cell epitope in pCol(28-40) were absent among expandin
117 ane protein (MOMP) contains serovar-specific B cell epitopes in four regions of the molecule whose am
119 The amino acid sequences of four putative B cell epitopes in the fusion (E1) protein of the rubell
120 itope mapping revealed major and minor T and B cell epitopes in the N-terminal, first, and second loo
121 ug delivery vehicle, T cell responses, T and B cell epitopes in the protein drug, and the associated
123 rs, we investigated how the accessibility of B cell epitopes in vivo influences the development of gl
125 ised against a peptide derived from a linear B-cell epitope in the N-terminal region of gelsolin iden
126 A, S462A, and D465A mutations targeting on a B-cell epitope in the OTU domain region generated the vi
127 mal model studies are identifying T-cell and B-cell epitopes in FVIII and characterizing the presenta
128 sed identification of individual immunogenic B-cell epitopes in major antigens of a pathogen remains
130 ole of TCP presentation in the generation of B-cell epitopes in order to optimize TcpA-based cholera
131 297 to 314) comprises a region of end-to-end B-cell epitopes in some serovars of the B and F/G serogr
135 ion and amino acid composition of all of the B-cell epitopes in the remaining 25-kDa portion of Pseud
137 We previously identified seven major mouse B-cell epitopes in the toxin, and subsequently silenced
140 ne PvMSP1P-19-specific antibody function and B-cell epitopes in vivax patients, five monoclonal antib
141 nd their deamidated forms, as immunodominant B-cell epitopes in wheat and related cereal proteins.
142 rovide useful but incomplete descriptions of B-cell epitopes, indicating that increased efforts to fu
143 is currently difficult, because the specific B-cell epitopes involved in toxin neutralization have no
147 rom a linear sequence window similarity to a B-cell epitope-like 3D surface similarity window which b
150 zing data on more than 900 peptides used for B-cell epitope mapping of immunodominant proteins of Chl
151 n contrast, researchers typically choose for B-cell epitope mapping short peptide antigens in antibod
154 of these studies showed that the B27.29 MUC1 B-cell epitope maps to two separate parts of the glycope
155 Antigenic variation in MSP2 Th cell and B cell epitopes may contribute to immune evasion that al
157 el CD4(+) T-cell epitopes as well as a novel B-cell epitope, Meu10, which encodes a glycosylphosphati
158 anti-GBM Ab was not related to the peptidic B cell epitope nested in pCol(28-40); that is, 1) elimin
159 ope vaccine that contains the immunodominant B cell epitope of Abeta in tandem with the synthetic uni
160 laria repeat peptide containing a protective B cell epitope of Plasmodium falciparum, the most lethal
161 eptide (PPPRMPPP) with similarity to a major B cell epitope of the snRNP core protein B were identifi
162 luenza viruses expressing the immunodominant B cell epitope of this CS protein produced high titers o
163 of neutralizing antibodies to conformational B cell epitopes of MSP119 Here, using the PfMSP1/8 const
164 itope vaccines, containing CTL, Th cell, and B cell epitopes of the human papillomavirus type 16.
165 ggests the hybrids to have the discontinuous B cell epitopes of the natural Ag 5 but with an altered
166 h a peptide vaccine containing minimal T and B cell epitopes of the Plasmodium falciparum circumsporo
167 ntibody LA-2 defines an important protective B-cell epitope of OspA against which protective sera hav
168 ts of the sequence Asn-Ala-Asn-Pro (NANP), a B-cell epitope of P.falciparum sporozoites, induced anti
169 ks, and it underlies the cryptic nature of a B-cell epitope of the alpha3.alpha4.alpha5 hexamer, impl
171 ay peptide libraries in determining dominant B-cell epitopes of allergens, in developing mimotope imm
172 l of the present study is to identify linear B-cell epitopes of EF and to determine the relative cont
175 amework is shown to reliably identify linear B-cell epitopes of human-adapted viruses given protein s
176 he present study were to identify sequential B-cell epitopes of LF and to determine the capacity of t
177 a branched peptide containing minimal T- and B-cell epitopes of Plasmodium falciparum CS protein elic
178 Pol expressed in insect cells, we mapped the B-cell epitopes of Pol recognized by these MAbs to amino
180 rane protein contains important neutralizing B-cell epitopes of relevance for antibody-mediated prote
181 epitope polypeptide that contains T-cell and B-cell epitopes of reported novel potential vaccination
185 c antibody repertoires to the immunodominant B-cell epitopes of the major peanut allergens Ara h 1 to
194 -CSF is driving the autoantibodies and not a B-cell epitope on a pathogen cross-reacting with GM-CSF.
195 with plague, suggesting that this protective B-cell epitope on rV is conserved between these three sp
196 including the fact that the key neutralizing B-cell epitopes on RTA have not been fully defined.
197 ever, in the absence of cross-reactive T and B cell epitopes, one lung infection can modify immunity
199 substitution of the critical residues of the B cell epitope or by truncation, failed to abrogate anti
202 adjuvant by noncovalently assembling a T and B cell epitope peptide into nanofibers using a short C-t
203 determinant that enhances the response to a B-cell epitope peptide of Plasmodium falciparum expresse
204 ore, the results suggest that conformational B cell epitopes play a more significant role in ovomucoi
205 bly several freely available structure-based B cell epitope prediction programs can identify already
207 AbEpiTope-1.0, a tool for antibody-specific B cell epitope prediction, using AlphaFold for structura
208 ts that are commonly used for development of B-cell epitope prediction approaches from protein antige
209 comes the well known inaccuracy of in silico B-cell epitope prediction from primary protein sequences
210 ins was conducted to assess whether existing B-cell epitope prediction methods, combined with compreh
212 of eight new tools were added, including two B-cell epitope prediction tools, four T-cell epitope pre
217 exhibit immunogenicity, whereby a variety of B-cell epitopes, predominantly in the amino terminus of
219 e Database, we found that only 31% (8/26) of B-cell epitopes present in recently circulating H1N1 str
221 that, inasmuch as contiguity between T- and B-cell epitopes provides enough signaling capacity to tr
222 against hybrid ubiquitin presenting the HIV B cell epitope reacted specifically with the foreign epi
224 ng homology between the pathogenic human MPO B cell epitope recognized by ANCA in patients with acute
225 d envelope protein containing several linear B cell epitopes recognized by neutralizing antibody.
228 d to T cell determinants located outside the B cell epitope region, because processing/presentation o
229 n disorder tendency is the best indicator of B-cell epitope regions for chlamydial and published data
235 tabase upon a dataset of 62,730 known linear B cell epitope sequences and considered as a B cell epit
236 ith antibiotic-resistant organisms, and some B-cell epitopes should be included in a subunit vaccine.
237 th the peptide vaccine or treatment with the B cell epitopes significantly reduced tumor growth in bo
238 Ag, in addition to within a known protective B-cell epitope (so-called group a determinant of HBsAg 1
239 framework to predict variable-length linear B-cell epitopes specific for human-adapted viruses with
241 These results present a new murine model of B cell epitope spreading and lupus autoimmunity induced
242 des harboring T cell epitopes can initiate a B cell epitope spreading cascade within the snRNP comple
244 rabbits develop anti-Sm autoantibodies with B cell epitope spreading of the autoimmune response as w
245 cipitation assays showed that intermolecular B cell epitope spreading to U1RNA-associated A ribonucle
247 ersified anti-GBM antibody response through "B cell epitope spreading." In this study, an expansion o
249 shows a cluster of mutations in a predicted B-cell epitope, suggesting immune-avoidance selection.
250 peptides containing the same minimal T- and B-cell epitopes, T1BT*, comprised of a CS-derived univer
252 lapped with regions in histones that contain B cell epitopes targeted by autoantibodies, as well as t
253 the resolution of Lyme disease, the specific B cell epitopes targeted during human infections remain
255 ls from B. bovis-immune cattle and that like B-cell epitopes, Th-cell epitopes are conserved in diffe
257 caques recognized a limited number of linear B cell epitopes that are highly conserved among orthopox
258 The apoptotic form of U1-70 kd displays B cell epitopes that are not displayed on the intact for
260 topes (5 HLA class I, 36 HLA class II) and 6 B cell epitopes that could serve as promising targets fo
261 we have identified and validated immunogenic B-cell epitopes that are cross-reactive between members
262 out 100 amino acids that encodes immunogenic B-cell epitopes that induce variant-specific antibodies
263 In an independent dataset incorporating 503 B cell epitopes, this method reached accuracy, specifici
264 onstrate previously unknown, highly reactive B cell epitopes throughout the full proteome of SARS-CoV
265 g M5 peptides revealed myosin-cross-reactive B-cell epitopes throughout the A and C repeat regions an
267 previously discovered C. pneumoniae-specific B-cell epitopes to 48 peptide antigens from 12 C. pneumo
268 enic RITs by identifying and removing T- and B-cell epitopes to hide the RIT from the immune system.
269 apsid is an efficient vehicle for presenting B-cell epitopes to the immune system, making this a usef
270 iously reported that we could eliminate most B-cell epitopes using a combination of point mutations a
272 from the GAS M protein (J14) representing a B cell epitope was incorporated alongside a universal T
274 c envelope containing only T-helper (TH) and B-cell epitopes was dependent on CD8+ T cells as well as
275 cell epitopes located within the autoimmune B cell epitope were suppressed in a dominant fashion.
277 nd immunogenic MHC class I, MHC class II and B cell epitopes were extracted from top-ranking vaccine
278 elop a multiepitope vaccine, 12 high ranking B cell epitopes were identified from the extracellular d
282 genes of HCV, encoding cytotoxic (CTL), and B cell epitopes were sequenced at 2 time points, 2 years
290 onse against HVR epitopes, T-cell and linear B-cell epitopes were localized by measuring peripheral b
292 alysis of protein antigenicity, and selected B-cell epitopes were synthesized colinearly with a promi
294 ication and validation of these neutralising B-cell epitopes will provide insights towards the design
299 gE Ab responses can be boosted by repetitive B cell epitopes without allergen-specific T cell help by
300 ctor VIII can be reduced by mutagenesis of a B-cell epitope without apparent loss of function, sugges