ライフサイエンスコーパス: B-cell-specific

1 er the control of its own promoter, which is B cell specific.

2 Here, we show that mice with B cell-specific ablation of both Cbl and Cbl-b (Cbl-/-Cb

3 Here we show that B cell-specific ablation of Nfat2 leads to the loss of t

4 B cell-specific ablation of TBK1 in mice resulted in unc

5 Here, B-cell-specific ablation of ST6Gal1 in mice revealed tha

6 expression was accompanied by corresponding bs cell-specific accumulation of the constitutively tran

7 While the B cell-specific Act1 knockout mice displayed a similar p

8 ta gene encodes for the transcription factor B cell-specific activating protein that, in turn, direct

9 The recombination is initiated by the B cell-specific activation-induced cytidine deaminase (A

10 matic hypermutation and CSR both require the B-cell-specific activation-induced cytidine deaminase pr

11 so show that Cp, like Wp, interacts with the B cell-specific activator protein BSAP/Pax5.

12 -kappaB, octamer binding proteins, and Pax5 (B cell-specific activator protein).

13 ve shown that the transcription factor BSAP (B-cell-specific activator protein) directly interacts wi

14 eir role in B cell development, we generated B cell-specific ADAM10 knockout mice.

15 bances in naive lymph node architecture from B cell-specific ADAM10-deficient mice (ADAM10(B-/-)) inc

16 We have developed B cell-specific ADAM10-deficient mice (ADAM10(B-/-)).

17 We propose that B-cell-specific AID-RPA complexes preferentially bind to

18 ther, these data confirm that M2 function is B cell-specific and demonstrate that M2 primarily functi

19 Relative to females, males had reduced B cell-specific and NK cell-specific transcripts and an

20 x class II (MHC-II) genes are regulated in a B-cell-specific and gamma interferon-inducible manner.

21 suggest that LMP2A enhances, not diminishes, B-cell-specific antibody responses in vivo and in vitro

22 B-cell lymphoma through coengagement of the B cell-specific antigen CD19 and the TCR/CD3 complex on

23 CD19 is a B cell-specific antigen expressed on chronic lymphocytic

24 ated with CAR-modified T cells targeting the B-cell-specific antigen CD19.

25 generation of therapeutics directed against B-cell-specific antigens (CD20, CD22) are being applied

26 therapeutic antibodies targeting alternative B-cell-specific antigens in CLL has been less successful

27 several conserved binding sites, general and B cell-specific, as well as key differences between fami

28 B cell-specific ATM deficiency attenuated the establishm

29 Thus, our study defines a proviral role of B cell-specific ATM expression during chronic gammaherpe

30 ct gammaherpesvirus tropism for B-1 B cells, B cell-specific ATM expression was necessary to support

31 B cell-specific B29 (Igbeta, CD79b) genes in rat, mouse,

32 ral 2'-F-modified RNA aptamers targeting the B-cell-specific BAFF-R with nanomolar affinity using in

33 In summary, we identified a novel role for B cell-specific, BAFF-dependent transmembrane activator

34 Socs2 induction seems B cell-specific, because no induction was observed in TC

35 esearch in the past few years has identified B cell-specific biomarkers able to predict optimal Ab re

36 F-1b, NERF-2 acts as a transactivator of the B cell-specific blk promoter.

37 Transgenic CD19-hBtk mice with B cell-specific BTK overexpression show spontaneous germ

38 However, using B cell-specific c-/N-myc double-knockout mice and E(mu)-

39 cell proliferation, we generated mice with a B cell-specific Casp8 deficiency.

40 rinitrophenol-LPS was selectively reduced in B cell-specific Casp8-deficient mice.

41 xpressed p53 protein only in the presence of B cell-specific CD19-Cre.

42 ltransferase produces Siglec ligands for the B-cell-specific CD22 lectin and sustains humoral immune

43 To address this issue, a B cell-specific CD40L transgene (CD40LBTg) was introduce

44 evidence suggests that they may recognize a B cell-specific CD45 isoform.

45 ned a model of specific antibody deficiency, B cell-specific CD79a-Cre x XBP1 (X-box binding protein-

46 erefore, in the present study we generated a B cell-specific CD83 conditional knockout (CD83 B-cKO) m

47 Our study establishes a central role for GC B cell-specific CD84 and Ly108 expression in maintaining

48 -specific transcription factor PAX5, and the B-cell-specific cell surface protein CD19.

49 In addition, immunization of mice with B cell-specific cFLIP deletion resulted in selective rec

50 The resulting B cell-specific cFLIP-deficient mice were found to have

51 element does not support recruitment of the B cell-specific co-activator OBF-1 and that CD36 express

52 Here we show that OCA-B, a B cell-specific coactivator essential for germinal cente

53 B cell-specific coactivator OCA-B, together with Oct-1/2

54 ence) or inaccessible (MORE sequence) to the B-cell-specific cofactor OBF1 (OcaB, Bob1).

55 l mobility shift assays show that DICE forms B cell-specific complexes that were also sensitive to DI

56 ted two mouse models of Pol zeta function: a B cell-specific conditional knockout and a knock-in stra

57 Employing B cell-specific conditional knockout mice, we have demon

58 Using transgenic mouse models, we show that B-cell-specific constitutive activation of HH/GLI signal

59 B cell-specific cullin 3-deficient mice show reduced dev

60 Switch recombination depends upon the B cell-specific cytidine deaminase, AID, and conserved D

61 B-cell-specific deficiency in FcmuR enhanced the spontan

62 To test this idea, we used mice with B cell-specific deletion of a floxed cFLIP allele.

63 The B cell-specific deletion of ATF2 and ATF7 in mice result

64 Mice with B cell-specific deletion of Atg7 (B/Atg7(-/-) mice) show

65 In this study, we demonstrate that B cell-specific deletion of ATM in mice leads to reducti

66 In this report, we show that mice bearing B cell-specific deletion of beta-catenin have normal B c

67 y reduced peripheral T cell numbers, whereas B cell-specific deletion of FADD led to increased periph

68 Moreover, mice with B cell-specific deletion of Fra1 show enhanced plasma ce

69 Furthermore, B cell-specific deletion of Glut1 led to reduced B cell

70 B cell-specific deletion of IL-10 worsened cardiac funct

71 In this study, we define the consequences of B cell-specific deletion of PIK3IP1.

72 We have created mice with a B cell-specific deletion of prdm1, the gene encoding Bli

73 We in this study report that B cell-specific deletion of relb led to only a slight de

74 We found that B cell-specific deletion of Ship2, but not of its close

75 B cell-specific deletion of T-bet was also associated wi

76 We report here that B cell-specific deletion of the heavy chain of CD98 (CD9

77 We report that GC B cell-specific deletion of the NF-kappaB subunits c-REL

78 Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, an

79 Panhematopoietic or B cell-specific deletion of Zfx in the bone marrow block

80 in plasma cell development, later studies of B cell-specific deletion reported a much milder conseque

81 B-cell-specific deletion of AP4 resulted in reduced GC s

82 We show that B-cell-specific deletion of Max has a modest effect on B

83 Here we show that B-cell-specific deletion of TAK1 impaired the transition

84 We generated mice with an inducible and B-cell-specific deletion of the Syk gene and found that

85 t is independent of T-cell exhaustion, using B-cell-specific deletion of the transcription factor IRF

86 documented an important therapeutic role of B cell-specific depletion.

87 B-cell-specific depletion of pVHL leads to constitutive

88 The B cell-specific ELL2 conditional knockouts (cKOs; ell2(l

89 bination of transcription factors results in B cell-specific enhancer activation.

90 enome wide, KAP1 binding sites lacked active B cell-specific enhancers and were enriched in repressiv

91 SHM is dependent on the action of the B cell specific enzyme, activation-induced cytidine deam

92 The B cell-specific enzyme activation-induced cytidine deami

93 -specific phospholipase C gamma 2 (PLCG2), a B cell-specific enzyme that stimulates intracellular Ca(

94 vation-induced cytidine deaminase (AID) is a B-cell-specific enzyme that targets immunoglobulin genes

95 LigA (LK90) based B-cell specific epitopes were predicted and synthesised

96 Direct binding of Gfi1b to a site 5' of the B cell-specific Erag enhancer results in epigenetic chan

97 However, the B-cell-specific events that activate CD79b do not trigge

98 targets for the use of ADCs because they are B-cell-specific, expressed in non-Hodgkin lymphomas (NHL

99 Its B cell-specific expression makes it an attractive target

100 cription factor, Oct-2, is essential for the B cell-specific expression of CD36 in mouse B cells.

101 s provide evidence that HSS1 is required for B cell-specific expression of CIITA and that HSS1 functi

102 B cell-specific expression of immunoglobulin heavy chain

103 small subunit), in themselves, confer strong bs cell-specific expression to gfpA reporter gene transc

104 ates CSR by transcriptionally activating the B cell-specific factor activation-induced cytidine deami

105 is induced by targeted DNA deamination by a B cell-specific factor, activation induced cytidine deam

106 ing B cell commitment, the expression of the B-cell-specific factor Pax5 sharply alters the temporal

107 ress activation-induced deaminase (AID), the B-cell-specific factor that deaminates DNA to initiate i

108 metabolism, and decreases the expression of B-cell-specific factors and genes associated with immuni

109 In this report, we generated B cell-specific FADD-deficient mice and showed that dele

110 nd immature B cells are reduced by 30-40% in B cell-specific FAK knockout mice.

111 ers, full FcgammaRIIb knockout (KO), but not B cell-specific FcgammaRIIb KO, mice showed a significan

112 B cell-specific Fcmr(-/-) mice lacked robust clonal expa

113 nsion and activation of transitional splenic B cells specific for 2F5's nominal gp41 MPER-binding epi

114 expressing this Ag, even though autoreactive B cells specific for alpha345NC1 hexamers are not purged

115 munization regimens, or it may indicate that B cells specific for broadly neutralizing Env determinan

116 erfered with TG2 cross-linking activity, and B cells specific for C-terminal epitopes were inefficien

117 Similarly, a fraction of naive human B cells specific for clinically-relevant Ags derived fro

118 -liposome prime:boosting in rabbits to drive B cells specific for cross-conserved sites.

119 B cells specific for DENV precursor membrane protein, en

120 B cells specific for Der p 1 were detected by using the

121 B cells specific for DEX enrich in the marginal zone (MZ

122 contains a high frequency of "dual reactive" B cells specific for DNA-based autoantigens such as chro

123 predominantly derived from activated memory B cells specific for epitopes conserved in several influ

124 is a common feature of populations of naive B cells specific for foreign Ags and a moderate level of

125 The mean frequencies of B cells specific for HLA-B7 were the same in rituximab-t

126 s have shown that the Ag receptors (BCRs) on B cells specific for nuclear autoantigens can facilitate

127 nerated a variable light chain library using B cells specific for PPS4 and PPS14 from each vaccinated

128 nsion of a pre-existing population of memory B cells specific for stem epitopes.

129 B cells specific for TG2 and modified gluten peptides ar

130 g, kynureninase, and that the development of B cells specific for the 2F5 epitope is constrained by i

131 fectively expand both low- and high-affinity B cells specific for the antigenic bait during immunizat

132 , despite the presence of circulating memory B cells specific for the corresponding Ags.

133 ve B cell repertoire of DBA/2 mice has fewer B cells specific for the DNA mimetope.

134 B cells specific for the major bee venom allergen phosph

135 B cells specific for the major bee venom allergen PLA is

136 tudy, we describe regulation of autoreactive B cells specific for the ribonucleoprotein Smith (Sm) at

137 We isolated B cells specific for the SARS-CoV-2 envelope glycoprotei

138 tematic changes in the frequencies of memory B cells specific for the two other PfEMP1 proteins were

139 Self-reactive B cells specific for ubiquitous membrane-bound autoantig

140 FSE staining in combination with T-cell- and B-cell-specific gating allowed discriminating between al

141 scriptional regulator that antagonizes T and B cell-specific gene expression programs.

142 he cytidine deaminase AID) and thus silenced B cell-specific gene expression, antigen presentation an

143 ve DNA binding of MEF2A and into its role in B cell-specific gene regulation.

144 +/-)Runx1(+/-) (ER(het)) mice, activation of B cell-specific gene transcription was depressed in thes

145 Surprisingly, B-cell-specific gene expression was negatively correlate

146 In this context, B cell-specific genes and mTOR signaling were associated

147 essing Cbfbeta-SMMHC also show inhibition of B cell-specific genes Cd79a, Igll1, VpreB1, and Blk.

148 lymphopoiesis and activates transcription of B cell-specific genes in the absence of upstream regulat

149 plasmacytoma cells activated multiple early B cell-specific genes synergistically.

150 Several B cell-specific genes were either not expressed or were

151 progenitors, with a concurrent repression of B cell-specific genes.

152 e E-box site, found in regulatory regions of B cell-specific genes; promote cell survival of early pr

153 It activates transcription of several B-cell-specific genes, including the lambda5 gene, which

154 The activation of B-cell-specific genes, such as CD19 and PAX5, is a hallm

155 we established a mouse model of CLL in which B-cell-specific genetic ablation of ILK resulted in dece

156 5 (BSAP) is required for the expression of a B-cell-specific genetic program and for B-cell different

157 In transformed leaf regions, strong bs cell-specific GFP expression was accompanied by corre

158 B cell-specific gilz KO mice confirmed that the effect o

159 s of HSP90b1 in B-cell biology in vivo using B-cell-specific HSP90b1-null mice.

160 ndidate Igh regulatory region defined by pro-B cell-specific hypersensitivity and interaction with fa

161 n 3 (Id3) in the regulation of B-1b cells as B-cell-specific Id3 knockout mice (Id3(BKO)Apoe(-/-)) ha

162 ld type MZP B cells but not other subsets to B cell-specific IL-10 deficient mice prevented graft rej

163 flow cytometry, IL-10 reporter (Vert-X) and B cell-specific IL-10 knockout mice, migration assays, a

164 Use of a novel B cell-specific IL-10 knockout mouse revealed that B cel

165 B cells from naive controls, and mice with a B cell-specific IL-6 deficiency showed less severe disea

166 in ST2(-/-) , IL-4(-/-) , IL-4Ralpha(-/-) or B-cell-specific IL-4Ralpha(-/-) mice, demonstrating IL-3

167 2(-/-) , IL-4(-/-) , IL4Ralpha(-/-) and T-or B-cell-specific IL-4Ralpha(-/-) mice.

168 To further understand how B-cell-specific immunoglobulin promoter expression is me

169 The results of B cell-specific immunotoxin therapy may have clinical im

170 esults show that (1) the immunoconjugate has B-cell-specific in vitro and in vivo cytotoxicity; (2) B

171 Using B cell-specific inactivation of the critical HR factor B

172 ue eosinophilia-regulating function for the "B cell-specific" inhibitory molecule CD22 on GI eosinoph

173 Wild type C57BL/6, or B cell-specific interleukin (IL)-10 (CD19-Cre::IL-10) mi

174 Surprisingly, B cell-specific IRF-1 deficiency attenuated the establis

175 Further, we found that B cell-specific IRF-1 deficiency led to reduced levels o

176 matin occupancy at sites in the Igh locus is B cell specific, is correlated with histone H4 lysine 20

177 cinoma cells is primarily mediated by IL-8, (b) cell-specific isoforms of IL-8 with distinct osteocla

178 Igbeta protein is considered B-cell specific; its only known role is in B-cell recept

179 cells by establishing a mouse strain with a B cell-specific JAB1 deletion.

180 n a B cell line and generating a conditional B cell-specific Kidins220 knockout (B-KO) mouse strain,

181 We report that B cell-specific KLF2 deficiency leads to decreased expre

182 pe B cells are present in neonatal mice with B cell-specific KLF2 deficiency, suggesting that B1 diff

183 Using B cell-specific knockdown strategies, we confirmed the r

184 In this study, we show that mice with B cell-specific knockout of caspase-9 had decreases in G

185 ed GC B cells and Ab production in mice with B cell-specific knockout of caspase-9.

186 M levels were reduced in ApoE(-/-) mice with B-cell-specific knockout of CXCR4, and overexpression of

187 CSR, were lower in B cells from both KI and B cell-specific KO mice, concomitant with increases in p

188 oid and full FcgammaRIIb KO mice, but not in B cell-specific KO mice, whereas disease severity was on

189 RP105 is a TLR homolog thought to be mostly B cell specific, lacking a signaling domain.

190 covery and functional elucidation of a human B cell-specific lncRNA with high levels of expression in

191 in mp cells) plays a key role in determining bs cell-specific localization of the rubisco enzyme.

192 nd accompanied by a male-specific decline in B-cell specific loci.

193 In this study, we show that the B cell-specific loss of GRK2 severely disrupts B cell tr

194 We demonstrate that B cell-specific loss of T-bet prevents control of persis

195 nic architecture resembling that observed in B-cell-specific lymphotoxin-beta-deficient mice, includi

196 B cell-specific Lyn mutant mice also develop myeloprolif

197 Within 8 mo of life, B cell-specific Lyn mutant mice develop high titers of I

198 eversed the autoimmune phenotype observed in B cell-specific Lyn-deficient mice by blocking productio

199 The B cell-specific Lyn-deficient mice have no defects in ea

200 The anti-CD20, B-cell-specific mAb rituximab (RTX) has been approved fo

201 and established disease, we screened several B cell-specific mAbs and found that a combination of ant

202 ic mouse that expresses inducible ABF-1 in a B cell-specific manner was generated to demonstrate that

203 ain but retains the DNA-binding domain, in a B cell-specific manner.

204 activation of BATF is mediated by EBNA2 in a B-cell-specific manner and is duplicated in non-EBV-infe

205 ntegrations at Ebfaz or Evi3 express the pre-B-cell-specific marker immunoglobulin lambda chain 5, an

206 Bright/Dril1/ARID3a is a B cell-specific, matrix association (or attachment) regi

207 D complexes greatly reduce activation of the B cell-specific mb-1 (Cd79a) gene by the transcription f

208 The early B cell-specific mb-1 promoter was hypermethylated at CpG

209 sed Pax-5 protein activates endogenous early B-cell-specific mb-1 genes in plasmacytoma cells, but on

210 Fc receptor homolog 4 (FcRH4) is a B cell-specific member of the recently identified family

211 inical target for B-cell lymphoma is CD22, a B-cell-specific member of the sialic acid binding Ig-lik

212 Despite the leakiness in the system, B cell-specific MHCII deletion resulted in substantially

213 Here we show that B cell-specific miR-17~92 transgenic mice developed lymp

214 CD19 is a B cell-specific molecule that serves as a major costimul

215 It is clear that antibodies targeting other B-cell-specific molecules, such as CD22, also offer pote

216 In this study, we examine the role of Bmi-1 (B-cell-specific Moloney murine leukemia virus integratio

217 B-cell-specific Moloney murine leukemia virus integratio

218 A B-cell-specific monoclonal antibody, rituximab, may be a

219 he role of Mule in B lymphocyte homeostasis, B cell-specific Mule knockout (BMKO) mice were generated

220 stasis and activation, which in concert with B cell-specific MyD88 signaling pathways can drive the d

221 B-cell-specific N-WASP gene deletion causes enhanced and

222 antibody production is severely impaired in B-cell-specific Notch2-deficient mice that lack marginal

223 Co-transfection of the B cell-specific octamer transcriptional co-activator Bob

224 Concomitant B cell-specific overexpression of the antiapoptotic prot

225 on-B cell lines, and also selectively by the B cell-specific pathway involving B cell receptor cross-

226 The B-cell-specific Pax5 also promotes the transcription of

227 Blockage of B cell-specific PD-L1 restored Th1 responses.

228 B cell-specific Pdia1 deletion in young high-fat diet fe

229 t mouse models its mutation has a relatively B cell-specific phenotype.

230 .1 gene is upstream of the gene encoding the B cell-specific phospholipase C gamma 2 (PLCG2), a B cel

231 x with the TLR adaptor protein MyD88 and the B cell-specific positive regulator of TLR signaling TAB2

232 We developed a new B cell-specific PPARgamma (B-PPARgamma) knockout mouse a

233 cific molecules and also by interfering with B-cell-specific pro-survival signals.

234 SR DSBs could be promoted by IgH-specific or B-cell-specific processes or by general aspects of chrom

235 of Ets factors with AML1 in the context of a B cell-specific promoter might help to determine the fun

236 erent immunoglobulin promoters and two other B-cell-specific promoters have higher activities in the

237 wn-regulation in the expression of HLA-DO, a B cell-specific protein known to interfere with HLA-DM f

238 re ablated in mice and humans lacking AID, a B cell-specific protein of unknown molecular activity.

239 fied and validated, revealing a role for the B cell-specific protein Pax5 in viral gene regulation an

240 The human B cell-specific protein, CD79b (also known as Igbeta and

241 unction of viral load, while transcripts for B cell-specific proteins and neutrophil chemokines were

242 We show that mature B cell-specific PTEN overexpression enhances CSR.

243 Mice with a B cell-specific PTP1B deficiency show increased T cell-d

244 se of the severe osteopetrosis--we generated B cell-specific RANK knockout mice.

245 hat NOTCH1 transactivates MYC via binding to B-cell-specific regulatory elements, thus implicating th

246 ation, we performed systematic analysis of a B-cell-specific regulatory model exhibiting follicular l

247 a are consistent with the silencing of a pre-B cell-specific replication program in the fusion hybrid

248 perhaps because of the presence of a strong B-cell-specific repressed chromatin conformation on the

249 ce of Chlamydia infection, consistent with a B cell-specific role of Rab7.

250 in the bone marrow was largely normal in the B cell-specific S1pr1 knockout (B-S1pr1KO) mice, their n

251 We generated B cell-specific Shp-1 and Syk double-knockout (DKO) mice

252 block at the pro/pre-B cell stage, whereas a B cell-specific Shp-1 deficiency promoted B-1a cell deve

253 CD22 is a B cell-specific sialic acid-binding immunoglobulin-like

254 CD22 is currently recognized as a B cell-specific Siglec and has been exploited therapeuti

255 By recapitulating two basic features of B-cell-specific somatic hypermutation, G/C mutations tar

256 l bone loss (p < 0.001), whereas T cell- and B cell-specific Stat3 mice were resistant, suggesting th

257 multiple complex isoforms, including several B cell-specific surface receptors.

258 B cell-specific survival ligand concentrations were meas

259 CD20 is a widely validated, B cell-specific target for therapy in B cell malignancie

260 This promoter is B-cell specific, though it is a weak promoter.

261 Thus, B cell-specific Tlr9 deficiency unlinked disease from au

262 Critically, B cell-specific Tlr9 overexpression resulted in ameliora

263 In conclusion, E1E2 can prime B cells specific to conserved neutralizing epitopes, but

264 s, spontaneous Ab secreting cells and memory B cells specific to influenza hemagglutinin were primari

265 Second, B cells specific to the peptidic B cell epitope in pCol(

266 al tolerogenic effects of these HEL forms on B cells specific to this Ag.

267 Induction of immune tolerance on memory B cells specific to transplantation carbohydrate antigen

268 ng splenic B cells purified from young adult B cell-specific Traf3 (-/-) and littermate control mice.

269 B cell-specific TRAF3 deficiency results in enhanced via

270 B cells of B-cell-specific TRAF3(-/-) mice (B-Traf3(-/-)) display r

271 B-cell-specific Traf3(-/-) mice displayed severe periphe

272 Additionally, we observe a B cell-specific trans association of rs11171739 at 12q13

273 The B cell-specific transcription factor BACH2 is required f

274 TCR targeting a peptide of the intracellular B cell-specific transcription factor BOB1 presented in t

275 Here we demonstrate that the B cell-specific transcription factor BSAP/Pax5 binds to

276 stage due to insufficient expression of the B cell-specific transcription factor EBF and its target

277 of numerous genes via the regulation of the B cell-specific transcription factor PAX5.

278 the prior binding of the macrophage- and the B cell-specific transcription factor PU.1 and exhibit hi

279 ells by epigenetic mechanisms, the lack of a B cell-specific transcription factor, and likely by the

280 PAX5, a B cell-specific transcription factor, is overexpressed t

281 cer regions overlapped with binding sites of B cell-specific transcription factors (TFs) and the degr

282 ulations were defined based on expression of B cell-specific transcription factors Pax-5 and B lympho

283 quires the Notch1 pathway to alter levels of B cell-specific transcription factors, E2A and EBF.

284 e stages of B-cell development by regulating B-cell specific transcription.

285 Since the B-cell-specific transcription factor Oct-2 also directly

286 o be determined by at least two factors: the B-cell-specific transcription factor Pax5 and linker his

287 In this report, we show that the B-cell-specific transcription factor Pax5 helps to promo

288 These cells consistently express the B-cell-specific transcription factor PAX5, and the B-cel

289 ome 9p13 result in reduced expression of the B-cell-specific transcription factor PAX5.

290 nf complex), increased transcription via the B-cell-specific transcription factor Pax5/BSAP.

291 BACH2, a B-cell-specific transcription factor, plays a critical r

292 OCA-B is a B cell-specific transcriptional coactivator for OCT fact

293 ed positively by STAT5 and negatively by the B-cell-specific transcriptional repressors BACH2 and BCL

294 When expressed as a B cell-specific transgene in mice, LMP2A drives B cell d

295 antiapoptotic protein Bcl-x(L) or Bcl-2 as a B cell-specific transgene.

296 mphomagenesis/leukemogenesis, we generated a B-cell-specific transgenic mouse model with targeted ove

297 Strikingly, B-cell-specific transgenic overexpression of spry2 in mi

298 mechanism of histone exchange, thus allowing B cell-specific V(H)-to-DJ(H) recombination.

299 body VDR KO, T cell-specific VDR (T-VDR) KO, B cell-specific VDR (B-VDR) KO, and vitamin D deficient

300 estricted LANA gene expression could explain B-cell-specific viral persistence.