ライフサイエンスコーパス: BDNF receptor

1 eurotrophin receptor p75 (p75(NTR)), the pro-BDNF receptor.

2 ctor BDNF, Numb binds to activated TrkB, the BDNF receptor, and functions both as an endocytic regula

3 1 at trkB brain-derived neurotrophic factor (BDNF) receptors, and BDNF neuroprotection is enhanced by

4 Administration of a BDNF receptor antagonist (the TrkB receptor antagonist A

5 be determined whether transport of TrkB, the BDNF receptor, depends on HTT and whether such transport

6 Mutants in the BDNF receptor gene trkB and antibodies to its second rec

7 ith neuroticism, and a locus overlapping the BDNF receptor gene, NTRK2.

8 [NTRK2, a brain-derived neurotrophic factor (BDNF) receptor gene, rs1211166, P = 1.04E-06] in the Pha

9 sting involvement of trkB (the high-affinity BDNF receptor) in BDNF-induced differentiation.

10 Intriguingly, the activity of TrkB, the BDNF receptor, is required in the cell body for the indu

11 wing for inducible, reversible disruption of BDNF receptor kinase activity by administration of 1NMPP

12 TrkB, the brain-derived neurotrophic factor (BDNF) receptor, selectively from D1+ or D2+ neurons oppo

13 the TrkB brain-derived neurotrophic factor (BDNF) receptor specifically localized to intracellular l

14 Activation of TrkB, the BDNF receptor, stimulates GCPs to secrete BDNF, thereby

15 RKB), the brain-derived neurotrophic factor (BDNF) receptor that promotes neuronal plasticity and ant

16 e pan-neurotrophin receptor p75(NTR) and the BDNF receptor TrkB (tropomyosin receptor kinase B) are n

17 and (4) prevents decreased activation of the BDNF receptor TrkB (tropomyosin-related kinase B), all a

18 ly, we found that systemic administration of BDNF receptor TrkB agonist, LM22A-4, dampens habitual al

19 immunoreactivity for activated forms of the BDNF receptor TrkB and beta1-integrins, two synaptic rec

20 t increases in cAMP can rapidly activate the BDNF receptor TrkB and induce BDNF-dependent long-lastin

21 ignaling, we measured the mRNA levels of the BDNF receptor TrkB and of P/Q-type Ca(2+) channel alpha-

22 4R mutants, mouse mutants that expresses the BDNF receptor TrkB at a quarter of the normal amount sho

23 tiviral vectors were used to overexpress the BDNF receptor trkB in layer V corticospinal motor neuron

24 hat bind to PSD-95 promoted signaling by the BDNF receptor TrkB in the hippocampus and reduced depres

25 Here, we show that inhibition of the BDNF receptor TrkB increases voluntary ethanol consumpti

26 ults, we hypothesized that activation of the BDNF receptor TrkB is necessary for the effects of BDNF

27 Here we report that the number of BDNF receptor TrkB on the surface of hippocampal neurons

28 ing evidence suggests that activation of the BDNF receptor TrkB promotes epileptogenesis caused by st

29 1, a protein that couples activation of the BDNF receptor TrkB to downstream signaling pathways regu

30 to ethanol results in the activation of the BDNF receptor TrkB, leading to the activation of the mit

31 removal of the endogenous BDNF by using the BDNF receptor TrkB-Fc fusion protein inhibited the forma

32 e and precursor BDNF protein, as well as the BDNF receptor TrkB.

33 corpuscles, a mechanoreceptor expressing the BDNF receptor TrkB.

34 Here, we show that the BDNF receptor TrkB.T1 is expressed by pancreatic beta-ce

35 LR animals a downregulation of the inactive BDNF receptor TrkB.T1, associated with an activation of

36 vation of brain-derived neurotrophic factor (BDNF) receptor TrkB, facilitation of mammalian target of

37 on of the brain-derived neurotrophic factor (BDNF) receptor trkB.T1, a truncated isoform of BDNF.

38 heat-shock cognate protein-70 as well as the BDNF receptor (trkB) and protein kinases, as determined

39 mortem human subjects with major depression, BDNF receptor (TRKB) expression, but not BDNF, was reduc

40 of females, though the HVC of both sexes has BDNF receptors (TrkB).

41 tive, green fluorescent protein (GFP)-tagged BDNF receptors (TrkB-GFP) in live cells during retrograd

42 tudy, we found that 5-HT treatment increases BDNF receptor, TrkB (tropomyosin related kinase B), leve

43 re associated with reduced activation of the BDNF receptor, TrkB, and that pharmacologic activation o

44 The BDNF receptor, TrkB, is critical to limbic epileptogenes

45 ls about the subcellular localization of the BDNF receptor, TrkB, relative to synaptic and nonsynapti

46 noadhesin chimera (TrkB-IgG) that mimics the BDNF receptor, TrkB, to selectively block BDNF in the hi

47 ophin independence, transcripts encoding the BDNF receptor, TrkB, were expressed at very low levels.

48 d subsequent activation of the high-affinity BDNF receptor, TrkB.

49 For example, activation of the BDNF receptor tropomyosin receptor kinase B (TrkB) in th

50 Furthermore, the BDNF receptor tropomyosin receptor kinase B (TrkB) was e

51 to locally knock down the expression of the BDNF receptor tropomyosin-receptor-kinase type B in rats

52 ternatively spliced truncated isoform of the BDNF receptor tropomyosin-related kinase B.T1 (trkB.T1).

53 NF scavenger or by intracellular blockade of BDNF receptor [tropomyosin-related kinase B (TrkB)] sign

54 t can be reversed by directly activating the BDNF receptor, tropomyosin receptor kinase B.

55 on of the brain-derived neurotrophic factor (BDNF) receptor tropomysin-related kinase B (TrkB).

56 to induce long-term depression, and with the BDNF receptor tyrosine kinase TrkB to elicit long-term p

57 SE-induced activation of the BDNF receptor tyrosine kinase, TrkB, is one signaling pa

58 The BDNF receptor tyrosine kinase, TrkB, underlies nervous s

59 ncated, kinase-deficient isoform (T1) of the BDNF receptor tyrosine receptor kinase B (trkB).

60 se is accompanied by the upregulation of the BDNF receptor, tyrosine kinase B (TrkB).

61 ice (TrkB-PV(-/-)) in which the gene for the BDNF receptor, tyrosine kinase B receptor (trkB), has be

62 Activation of BDNF receptors using a pharmacological agonist was also

63 r tyrosine kinase B (trkB) demonstrated that BDNF receptors were present on corticospinal neuronal so

64 of these neurons were positive for TrkB, the BDNF receptor with a tyrosine kinase activity.