ライフサイエンスコーパス: BUN

1 BUN levels at 24 wk were reduced from 68.8 +/- 9.7 mg/dl

2 BUN levels were persistently higher among nonsurvivors t

3 BUN measurements confirmed renal protection at 48 hr in

4 BUN, serum creatinine concentration and urinalysis were

5 OR 2.35, 95% CI 1.01, 5.49; P-value = 0.04), BUN levels (red meat: OR 2.56, 95% CI 1.10, 5.93; P-valu

6 68-69 [10] years; 49.7%-51.5% female), 2479 (BUN) to 3195 (potassium) were analyzed, depending on ava

7 ](0.516) x [1.8/cystatin C (mg/L)](0.294)[30/BUN (mg/dl)](0.169)[1.099](male)[height (m)/1.4](0.188).

8 .15+/-0.3 vs. Group C = 2.10+/-0.06; Group A BUN = 27.0+/-6.0 vs. Group C = 31.1+/-6.4).

9 59+/-0.63 vs. Group C = 12.8+/-1.01; Group A BUN = 64.1+/-2.73 vs. Group C = 104.9+/-12.21)--however,

10 Combining admission BUN and change in BUN at 24 hours produced an AUC of 0.9

11 An elevated admission BUN/Cr identifies decompensated patients with heart fail

12 ably, in patients with an elevated admission BUN/Cr, the risk of death associated with RD (estimated

13 However, higher admission BUN/Cr was also associated with post-discharge worsening

14 Higher admission BUN/Cr was associated with in-hospital IRF (odds ratio,

15 However, in patients with a normal admission BUN/Cr, RD was not associated with increased mortality (

16 was used to evaluate the impact of admission BUN, change in BUN, admission Hgb, and change in Hgb on

17 shared among all the groups, namely Albumin, BUN, NLR and Pulse, using univariate analysis and multip

18 tamin B12 (P=0.05), creatinine (P=0.03), and BUN (P=0.05), and blood cyclosporine trough level (C0, P

19 ly increased serum phosphate, 1,25(OH)2D and BUN, and decreased serum PTH and FGF23, relative to vehi

20 were demonstrated between breath ammonia and BUN (0.86 to 0.96), which demonstrates the possibility o

21 gave an R(2) of 0.95 for breath ammonia and BUN correlation and an R(2) of 0.83 for breath ammonia a

22 ion between breath ammonia concentration and BUN and creatinine.

23 ressure, serum creatinine concentration, and BUN were obtained at baseline, during treatment with aml

24 Peak Cr and BUN (mg%) were significantly greater in Group C vs. Grou

25 By contrast, in P-/- creatinine and BUN increased only moderately (fourfold over sham).

26 findings but did reduce serum creatinine and BUN, as observed in patients with CKD.

27 to investigate the associations of eGFR and BUN with risk of incident CHD in the prospective Dongfen

28 n serum blood urea nitrogen (BUN) levels and BUN: Creatinine ratio indicated potential liver and kidn

29 In contrast, proteinuria and BUN levels were significantly reduced in mice treated wi

30 y (MDRD) formula that age, gender, race, and BUN account for creatinine production (CP).

31 ith CP independent of age, gender, race, and BUN.

32 earlier than the clinically popular sCr and BUN methods.

33 poor sensitivity and specificity of SCr and BUN, we used rat toxicology studies to compare the diagn

34 Compared with wild-type animals, BUN at 12 months was higher in cystinotic mice fed with

35 d liver and kidney function tests (ALT, AST, BUN, total protein) following short- and long-term treat

36 etabolic control, which is the time-averaged BUN (BUNa) or steady-state BUN (BUNs) for intermittent h

37 ROC analysis identified baseline BUN (P = .026, area under ROC curve [AUC] = 0.818), cyst

38 primary outcome was the interaction between BUN- and HDLD-associated mortality.

39 in-induced increases in the serum biomarkers BUN, creatinine, and neutrophil gelatinase-associated li

40 ime-averaged BUN (BUNa) or steady-state BUN (BUNs) for intermittent hemodialysis (IHD) or continuous

41 ely attenuated renal failure, as measured by BUN levels in mice fed an adenine diet known to cause re

42 ciation appeared to be partially mediated by BUN.

43 (BUN) level, creatinine (Cr) concentration, BUN:Cr ratio, and hepatic transaminase levels (P </= .05

44 ainment of intensive CRRT metabolic control (BUNs = 60 mg/dl), required urea clearance rates of appro

45 did not confer functional (serum creatinine, BUN and FITC-labeled inulin clearance) or histological p

46 nd no abnormalities in BP, serum creatinine, BUN, albuminuria, and histology.

47 , as indicated by elevated serum creatinine, BUN, and potassium.

48 Serum creatinine, BUN, folate and vitamin B12, and blood cyclosporine trou

49 level and recipients age, serum creatinine, BUN, folate concentrations, and creatinine clearance.

50 ly, there was no change in serum creatinine, BUN, or mean arterial pressure values.

51 se-dependent elevations in serum creatinine, BUN, uric acid, cystatin C, ACR, and KIM-1, indicating g

52 inuria (6.6 +/- 4.12 mg/24 hours), decreased BUN and serum creatinine levels (15.71 +/- 8.17 mg/dl an

53 ponse, increases estimated GFR and decreases BUN, serum phosphorus, and uric acid concentrations in p

54 a K (ml/h) versus patient weight for desired BUNs values of 60, 80, and 100 mg/dl were also generated

55 th significant reductions in cystic disease, BUN and serum creatinine levels.

56 educed survival in patients with an elevated BUN level and improved survival in patients with a norma

57 sient, and RD, in the setting of an elevated BUN/Cr, remains strongly associated with death.

58 longer folic acid therapy duration, elevated BUN and AST levels, VBG_HCO3 at initial record, and hemo

59 Late-exposed rabbits had elevated BUN and SCr relative to early-exposed.

60 AKI, those who have hyperkalemia or elevated BUN have a higher risk of death.

61 Of the 6 routine laboratory tests examined, BUN yielded the highest area under the concentration-tim

62 rry-Ig-treated mice developed renal failure (BUN > 50 mg/dl) compared with 18 of 38 (47.4%) mice in c

63 ictors for RHC placement: sepsis, PaO2/FIO2, BUN, and Pa.

64 sis, we also sampled the patient's blood for BUN and creatinine.

65 evidenced by improvements in renal function (BUN, creatinine, albuminuria), histologic injury and apo

66 eat EGF, IL-1alpha, IL-8, cortisol, glucose, BUN, and lactate concentrations or excretion rates durin

67 eat EGF, IL-1alpha, IL-8, cortisol, glucose, BUN, or lactate concentrations.

68 eat EGF, IL-1alpha, IL-8, cortisol, glucose, BUN, or lactate excretion rate.

69 = 11) developed severe LPS-induced ARF (24-h BUN 44.0 +/- 4.1 vs 112.1 +/- 20.0 mg/dl).

70 completely resistant to LPS-induced ARF (6-h BUN of 32.3 +/- 1.1 vs 61.7 +/- 5.6 mg/dl).

71 microalbuminuria, severe albuminuria, higher BUN level, and higher odds of DN.

72 ad significantly more albuminuria and higher BUN levels than MRL-lpr controls.

73 id doses, current and prior pain, and higher BUN levels were post-transplantation risk factors for gr

74 Analysis of histology, BUN, and urinary NGAL demonstrated marked phenotypic var

75 After 18 hours, BUN levels and renal cortical FC/CE content were determi

76 group E=3.99 +/- 1.5 mg%, and group B 72 hr BUN=241.3 +/- 32.8 mg% vs. group E=52.6 +/- 22.5 mg%).

77 strated reduced cystic enlargement, improved BUN and creatinine, and better survival than did Pkd(TKO

78 Combining admission BUN and change in BUN at 24 hours produced an AUC of 0.91 for mortality.

79 luate the impact of admission BUN, change in BUN, admission Hgb, and change in Hgb on mortality.

80 tudies revealed no significant difference in BUN between diabetic SPARC-null mice and diabetic WT mic

81 8 +/- 0.01 mg/min per 100 g) and increase in BUN (Intact, 20.3 +/- 2.1; OVX, 32.6 +/- 5.1; OVX+E(2),

82 For every 5-mg/dl increase in BUN during the first 24 hours, the age- and gender-adjus

83 ine the relationship between early trends in BUN and Hgb with respect to mortality.

84 Higher visit-to-visit variability in BUN (hazard ratio [HR] per 1-SD higher average successiv

85 The model (BALI), which included BUN >or=25 mg/dL, Age >or=65 years, LDH >or=300 IU/L, an

86 Mice injected with 15 mg/kg CP had increased BUN and serum creatinine and CP caused remarkable pathol

87 Serum markers of kidney injury, BUN, creatinine, and neutrophil gelatinase-associated li

88 lities included lower eGFR and higher levels BUN/creatine in blood and proteinuria.

89 lockers, digitalis use, blood urea nitrogen (BUN) >25, body mass index (BMI) > or =30 kg/m2, and New

90 .1 mg/dL; P = .008) and blood urea nitrogen (BUN) (27 vs 21 mg/dL; P = .006) decreased significantly.

91 o correlating well with blood urea nitrogen (BUN) (r = 0.61, p < 0.01, n = 96).

92 stoperative increase in blood urea nitrogen (BUN) and creatinine compared with those who did not (17-

93 Blood urea nitrogen (BUN) and creatinine levels were similar to untreated mic

94 by measurement of serum blood urea nitrogen (BUN) and creatinine, chemistries (sodium, potassium, chl

95 that were analyzed for blood urea nitrogen (BUN) and creatinine, which are the accepted standards in

96 h later for analysis of blood urea nitrogen (BUN) and kidney tissue (n = 8 per group).

97 At 6 weeks, blood urea nitrogen (BUN) and serum creatinine (SCr) levels were measured.

98 ked (100%) reduction in blood urea nitrogen (BUN) and serum creatinine and a highly significant reduc

99 mg/24 hours), increased blood urea nitrogen (BUN) and serum creatinine levels (39.86 +/- 13.45 mg/dl

100 lasma concentrations of blood urea nitrogen (BUN) and the cytokines interleukin-6 (IL-6) and IL-10, r

101 nd significantly higher blood urea nitrogen (BUN) and total and direct bilirubin and alkaline phospha

102 um creatinine (SCr) and blood urea nitrogen (BUN) are the primary options for monitoring kidney dysfu

103 um creatinine (SCr) and blood urea nitrogen (BUN) daily for 3 days, and neutrophil infiltration deter

104 reater than 15 seconds, blood urea nitrogen (BUN) greater than 50 mg/dL, intubation, performance stat

105 eart disease (CHD), and blood urea nitrogen (BUN) has been shown to be a strong predictor of mortalit

106 rum creatinine (SCr) or blood urea nitrogen (BUN) in monitoring generalized renal function after expo

107 rt rate, cardiac index, blood urea nitrogen (BUN) level, creatinine (Cr) concentration, BUN:Cr ratio,

108 n upward trend in serum blood urea nitrogen (BUN) levels and BUN: Creatinine ratio indicated potentia

109 irty h after injection, blood urea nitrogen (BUN) levels were 30.3 +/- 4.4 and 114.8 +/- 23.5 mg/dl f

110 cholesterol (LDL-C) and blood urea nitrogen (BUN) levels were decreased after the RS intervention.

111 um creatinine (SCr) and blood urea nitrogen (BUN) levels were evaluated postischemia.

112 poalbuminemia, elevated blood urea nitrogen (BUN) levels, and evidence of severe nephritis.

113 correlated it with the blood urea nitrogen (BUN) levels.

114 lkaline phosphatase and blood urea nitrogen (BUN) levels.

115 was not associated with blood urea nitrogen (BUN) or the BUN to creatinine ratio.

116 uate accuracy of serial blood urea nitrogen (BUN) versus serial hemoglobin (Hgb) measurement for pred

117 tion leads to increased blood urea nitrogen (BUN) within the body resulting in elevated levels of amm

118 ial mediating effect of blood urea nitrogen (BUN) within these associations has not been reported.

119 erfusion, AKI, elevated blood urea nitrogen (BUN), and hyperkalemia were associated with increased mo

120 L-8, cortisol, glucose, blood urea nitrogen (BUN), and lactate differ between tattooed and contralate

121 urohormonal activation, blood urea nitrogen (BUN), could identify patients destined to experience adv

122 psis, APACHE III score, blood urea nitrogen (BUN), creatinine, net fluid balance, and positive end-ex

123 atively associated with blood urea nitrogen (BUN), supernatant IL-4, serum IL-6, monoclonal immunoglo

124 of kidney injury, serum blood urea nitrogen (BUN), was only significantly increased compared to contr

125 ar changes were seen in blood urea nitrogen (BUN).

126 um creatinine (SCr) and blood urea nitrogen (BUN).

127 sus 0.77 +/- 0.2 mg/dl; blood urea nitrogen (BUN): 20.1 +/- 14.1 versus 10.3 +/- 3.28 mg/dl] than tho

128 72 hr plasma creatinine (CR); urea nitrogen (BUN); thromboxane B2 (TXB2) and 6-keto prostaglandin F(1

129 nificantly higher serum blood-urea-nitrogen (BUN) and creatinine levels.

130 R) patients (defined by blood urea nitrogen [BUN] >or=50 mg/dl and/or serum creatinine >or=2.5 mg/dl)

131 exhibited CKD (elevated blood urea nitrogen [BUN] and creatinine) and faithfully recapitulated the he

132 by 20 h of reperfusion (blood urea nitrogen [BUN] values, 46.6 +/- 6.9 and 68.4 +/- 7.9 mg/dl in C3 -

133 improved survival in patients with a normal BUN level.

134 ble logistic regression compared accuracy of BUN, Hgb, and additional routine laboratory tests.

135 The mediating effect of BUN was assessed to investigate the potential mechanism

136 nvestigate the potential mediating effect of BUN within these associations.

137 olimus showed side effects with elevation of BUN, cholesterol, triglycerides, and ALT after 120 days.

138 -severe decline in eGFR or a raised level of BUN might be associated with increased risk of incident

139 nitored by determination of plasma levels of BUN, creatinine, KIM-1 and NGAL.

140 r(db/db) mice exhibited increased markers of BUN, creatinine, NGAL, KIM-1, IL-6, cytochrome C, and HM

141 e injury and TFF3 augmented the potential of BUN and SCr to detect kidney damage.

142 ed with individuals in the lowest tertile of BUN, those in the highest tertile were at significantly

143 iated with HDLD use is strongly dependent on BUN concentrations with reduced survival in patients wit

144 with cold perception deficit, creatinine or BUN in the females.

145 Albumin outperformed either SCr or BUN for detecting kidney tubule injury and TFF3 augmente

146 o-body weight ratio, cystic index and plasma BUN levels, and was associated with increased renal tubu

147 Pre- and postdialysis BUN levels were reported in all children.

148 calculated from predialysis and postdialysis BUN measurements in patients receiving intermittent dial

149 ed for calculating PCRn from the predialysis BUN and Kt/V.

150 t/NLL)) + 0.168, where Co is the predialysis BUN in mg/dL.

151 Based on measurements of blood pressure, BUN, creatinine, albuminuria, genotyping and immunoblott

152 linear relationship, was utilized to produce BUN versus time curves by the direct quantification meth

153 in 43 gene (connexin 43+/-) had proteinuria, BUN, and serum creatinine levels significantly lower tha

154 Age, gender, race, BUN, and serum creatinine (Scr) were used to calculate M

155 ission blood urea nitrogen/creatinine ratio (BUN/Cr) could identify decompensated heart failure patie

156 Kim-1 outperforms SCr, BUN and urinary NAG in multiple rat models of kidney inj

157 tal-based cohort study, we identified serial BUN measurement as the most valuable single routine labo

158 nge of serum bilirubin, creatinine and serum BUN levels before and after the first treatment with ADV

159 igher levels of total kidney collagen, serum BUN, and urinary protein than Mrc2-sufficient Col4alpha3

160 on, decreased body mass, and increased serum BUN/creatinine ratio.

161 the time-averaged BUN (BUNa) or steady-state BUN (BUNs) for intermittent hemodialysis (IHD) or contin

162 Steady-state BUN versus time profiles for the same simulated patient

163 Mediation analysis showed that BUN mediated 12.4% of the association between the TyG in

164 emic vascular resistance, and changes in the BUN:Cr ratio(P </= .01).

165 ciated with blood urea nitrogen (BUN) or the BUN to creatinine ratio.

166 e not significantly different other than the BUN falling (p < 0.0001) after the preparation.

167 ata were available in real time, whereas the BUN and creatinine data were available generally 24 h la

168 e diagnostic performance of urinary Kim-1 to BUN, SCr and urinary N-acetyl-beta-D-glucosaminidase (NA

169 C3 deposition was inversely proportional to BUN values (r = -0.63; P < 0.001), which presumably indi

170 FR, urinary albumin-creatinine ratio (UACR), BUN, and serum urate.

171 y decreased after dialysis in agreement with BUN.

172 Four of five transgene-negative animals with BUN levels of > 100 mg/dl were anuric; the remaining ani

173 ephrectomy created a mouse model of CKD with BUN >80 mg/dl.

174 Serum AGE correlated with BUN (r = 0.6, P < 0.002 for CML; r = 0.4, P < 0.05 for M

175 ell C3 staining was strongly correlated with BUN values (r = 0.83, P < 0.001), as was C9 staining (r

176 In patients with BUN levels below the median, there was no associated ris

177 both of which correlated significantly with BUN values (P < 0.001).

178 In subjects with BUN levels above the median (21.0 mg/dl), both the unadj

179 ciation functional class >II, age >70 years, BUN >26 mg/dl, QRS duration >0.12 s, and atrial fibrilla