ライフサイエンスコーパス: Bartonella

1 known about in vivo virulence strategies of Bartonella.

2 ividually tested ticks were PCR positive for Bartonella.

3 ollected at Baird Ranch was PCR positive for Bartonella.

4 iales bacteria with affiliation to the genus Bartonella.

5 y Hill Open Space Reserve were infected with Bartonella.

6 Bacteria of the genus Bartonella, a member of the Alphaproteobacteria, are fas

7 Two species of Bartonella, a novel Bartonella clarridgeiae-like bacteri

8 rom bacteremic Bartonella spp., tested using Bartonella Alphaproteobacteria growth medium (BAPGM), we

9 ntly described clinical isolate, "Candidatus Bartonella ancashi," was obtained from a blood sample of

10 egree of identity with homologues from other Bartonella and alpha-Protebacteria.

11 logenetic analysis reveals a relationship to Bartonella and Brucella, which infect mammals.

12 ding the emerging human and animal pathogens Bartonella and Brucella.

13 argeting a 301-bp region of the ssrA gene of Bartonella and demonstrated specific amplification in ov

14 quences in the ITS region that are common to Bartonella and Mesorhizobium species, the amplification

15 association between the exposure of dogs to Bartonella and the exposure of dogs to A. phagocytophilu

16 pneumoniae, Mycobacterium tuberculosis, and Bartonella), and 13 viruses (parechovirus, dengue virus,

17 khoffii genomic expression library with anti-Bartonella antibodies led to the identification of the s

18 odels were used to assess the association of Bartonella antibody titer categories with potential risk

19 te negative blood cultures, the cat had high Bartonella antibody titers and B. henselae type I DNA wa

20 seropositive (titer of 1:4,096) for several Bartonella antigens (B. vinsonii subsp. berkhoffii, B. c

21 Members of the genus Bartonella are fastidious Gram-negative facultative intr

22 Bartonella are ubiquitous gram-negative pathogens that c

23 The mechanisms of Bartonella-associated vascular proliferation remain uncl

24 a previously uncharacterized resolvase from Bartonella bacilliformis ("Bart").

25 each other but phylogenetically distant from Bartonella bacilliformis and considerably divergent from

26 Bartonella bacilliformis causes bartonellosis, a potenti

27 Bartonella bacilliformis has caused debilitating illness

28 frame (ORF), showed significant homology to Bartonella bacilliformis IalA (invasion associated locus

29 Recombinant IalA protein from Bartonella bacilliformis is a monomeric adenosine 5'-tet

30 Genotypic diversity among 26 isolates of Bartonella bacilliformis obtained from different areas o

31 Bartonella bacilliformis was continuously internalized i

32 lone expressing an immunoreactive antigen of Bartonella bacilliformis was isolated by screening a gen

33 on-associated locus A and B genes (ialAB) of Bartonella bacilliformis were previously shown to confer

34 The groESL operon of Bartonella bacilliformis, a facultative intracellular, G

35 a clinical syndrome caused by the bacterium Bartonella bacilliformis, and is characterized by the de

36 the sole or principal vectors of Leishmania, Bartonella bacilliformis, and some arboviruses.

37 The causative agent, Bartonella bacilliformis, is endemic in specific regions

38 mpylobacter jejuni, Helicobacter pylori, and Bartonella bacilliformis, require flagellar motility to

39 The results of this study show that Bartonella bacilliformis, the agent of Oroya fever and v

40 d bacteremia from an organism that resembled Bartonella bacilliformis, the causative agent of Oroya f

41 ith the invasion of human red blood cells by Bartonella bacilliformis, the causative agent of several

42 by infection with the alpha-proteobacterium Bartonella bacilliformis.

43 of whom demonstrated previous infection with Bartonella bacilliformis.

44 ned genes by allelic exchange in a wild-type Bartonella background, which had not been achieved previ

45 Six (19%) of 31 Bartonella bacteremic coyotes exhibited the strain profi

46 By PFGE analysis, three Bartonella bacteremic coyotes were infected by a strain

47 Bartonella bacteria adhere to erythrocytes and persisten

48 and genotypes from cattle were identified as Bartonella bovis, both Bartonella species commonly found

49 Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during i

50 s revealed a cluster most closely related to Bartonella capreoli, and genotypes from cattle were iden

51 Human exposure to Bartonella clarridgeiae has been reported only on the ba

52 umented case of endocarditis associated with Bartonella clarridgeiae in any species.

53 inoculated with Bartonella henselae- and/or Bartonella clarridgeiae-infected cat blood and monitored

54 Two species of Bartonella, a novel Bartonella clarridgeiae-like bacterium and B. vinsonii s

55 ed primers that were designed to amplify the Bartonella consensus ITS region.

56 All Bartonella cultures were found to be negative.

57 In this study we compared some common Bartonella culturing methodologies using four diverse sp

58 sion in specific-pathogen-free cats and that Bartonella DNA can be detected in blood, brain, lymph no

59 Using this assay, we identified Bartonella DNA in 29% and 47% of blood specimens from el

60 repeats not found in any other bacterial or Bartonella DNA sequences.

61 in some Warthin-Starry stained sections, and Bartonella DNA was amplified from the lymph node (from 6

62 udy of the adaptation mechanisms employed by Bartonella during the transition between human host and

63 Bartonella effector protein A (BepA) of vasculotumorigen

64 Bartonella henselae or Bartonella elizabethae DNA from EDTA-anticoagulated bloo

65 tis E virus in this population was 13.6%; to Bartonella elizabethae, 12.5%; to B. quintana, 9.5%; to

66 eiae, and B. henselae), highly suggestive of Bartonella endocarditis.

67 o infection by undergoing apoptosis and that Bartonella evolved the antiapoptotic activity to enhance

68 , Babesia, Anaplasma, Rickettsia, Ehrlichia, Bartonella, Francisella, Powassan virus, tick-borne ence

69 nce analyses of gltA amplicons obtained from Bartonella from the rodents demonstrated considerable he

70 The most notable difference between Bartonella Fur and other Fur proteins was a substantiall

71 204 nucleotides immediately upstream of the Bartonella fur gene.

72 racterize antigens recognized by the host, a Bartonella genomic expression library was screened with

73 tA, a commonly used gene for differentiating Bartonella genotypes.

74 In this model, Bartonella grows in extracellular aggregates, embedded w

75 Four species of Bartonella have been reported to infect cats and dogs, a

76 Five species of Bartonella have been reported to infect humans and cause

77 Members of the genus Bartonella have historically been connected with human d

78 on at a sequence that is highly conserved in Bartonella hbp genes, which we designated the hbp family

79 oronary artery disease and seropositivity to Bartonella henselae (odds ratio [OR], 0.852; 95% confide

80 Bartonella henselae and B. koehlerae bacteremia was docu

81 Bartonella henselae and B. quintana induce an unusual va

82 ter membrane protein family of proteins from Bartonella henselae and Bartonella quintana, respectivel

83 ichia, and Rickettsia species, as well as on Bartonella henselae and Escherichia coli, and the assay

84 Sixty-five (24%) cats had Bartonella henselae bacteremia, and 138 (51%) cats were

85 Herein, we report a case of Bartonella henselae endocarditis involving prosthetic mi

86 We report the first feline case of Bartonella henselae endocarditis.

87 and it facilitated the primary isolation of Bartonella henselae from blood and aqueous fluid of natu

88 Bartonella henselae fur gene expression complemented a V

89 rovide molecular microbiological evidence of Bartonella henselae genotype San Antonio 2 (SA2) infecti

90 Bartonella henselae has only recently been isolated, cha

91 mechanism contributes to the persistence of Bartonella henselae in the chronically infected vascular

92 We report the first case of HLH due to Bartonella henselae infection in a patient with human im

93 alignancies, high-dose androgen therapy, and Bartonella henselae infection.

94 Bartonella henselae is a gram-negative pathogen that cau

95 Bartonella henselae is a recently recognized pathogenic

96 The gram-negative bacterium Bartonella henselae is capable of causing angiogenic les

97 Bartonella henselae is increasingly associated with a va

98 Bartonella henselae is known to cause central nervous sy

99 Bartonella henselae is one of the most common zoonotic a

100 A hallmark of Bartonella henselae is persistent bacteremia in cats des

101 Bartonella henselae is responsible for various disease s

102 Bartonella henselae is the causative agent of human cat

103 Using Bartonella henselae isolates from cats and a human, the

104 Bartonella henselae or Bartonella elizabethae DNA from E

105 egative pathogens were identified, including Bartonella henselae Pap31, Brucella Omp31, Agrobacterium

106 hat the closest homologs to HbpA include the Bartonella henselae phage-associated membrane protein, P

107 ector protein A (BepA) of vasculotumorigenic Bartonella henselae protects the infected human endothel

108 Using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell

109 s is usually made on the basis of increasing Bartonella henselae serum antibody titers.

110 ittens born to antibody-positive queens with Bartonella henselae to determine the contribution of ant

111 se functional transposon-mutant screening in Bartonella henselae to identify such factor as a pro-ang

112 We observed a CAMP-like reaction when Bartonella henselae was grown in close proximity to S. a

113 Bartonella henselae wound-associated infections suggest

114 rium tumefaciens and similar pathogens (e.g. Bartonella henselae) may also be able to transform human

115 In Bartonella henselae, 8 of the 10 virB operon genes share

116 at-scratch disease is an infection caused by Bartonella henselae, a fastidious gram-negative bacillus

117 etect and differentiate Bartonella quintana, Bartonella henselae, and Coxiella burnetii from surgical

118 ogens Brucella abortus, Brucella melitensis, Bartonella henselae, and Legionella pneumophila, which a

119 chronic infections, e.g., Brucella abortus, Bartonella henselae, and Legionella pneumophila.

120 rom animals known to be infected with either Bartonella henselae, B. clarridgeiae, or B. vinsonii sub

121 athogenic Bartonella species and subspecies: Bartonella henselae, B. quintana, B. washoensis, and B.

122 patient's blood and serum were negative for Bartonella henselae, Bartonella quintana, and B. bacilli

123 aciens, Bordetella pertussis, Brucella spp., Bartonella henselae, Helicobacter pylori and Legionella

124 with the facultative intracellular bacterium Bartonella henselae, is characterized by angiogenic lesi

125 ophils with intracellular pathogens, such as Bartonella henselae, Listeria monocytogenes, Legionella

126 Bartonella vinsonii subsp. berkhoffii, Bartonella henselae, or DNA of both organisms was amplif

127 human pathogens have emerged recently (e.g., Bartonella henselae, Rickettsia felis), and their mechan

128 Sera from patients who had a high titer for Bartonella henselae, the causative agent of bacillary an

129 ific-pathogen-free cats were inoculated with Bartonella henselae- and/or Bartonella clarridgeiae-infe

130 chia chaffeensis, Rickettsia rickettsii, and Bartonella henselae.

131 ilar to the VirB type IV secretion system of Bartonella henselae.

132 been identified upstream of the htrA gene of Bartonella henselae.

133 The veterinarian was coinfected with Bartonella henselae.

134 e an important new tool for investigation of Bartonella-host interaction.

135 of 273 bp of the gltA gene were applied for Bartonella identification.

136 The genus Bartonella includes numerous species with varied host as

137 Here, I establish in vitro models to study Bartonella-induced blood vessel formation.

138 thelioma, these results suggest that chronic Bartonella infection could have a role in the developmen

139 wildlife removal on per capita prevalence of Bartonella infection in either rodents or fleas.

140 who developed clinical signs compatible with Bartonella infection in Santa Clara County, Calif., this

141 opod exposure as a potential risk factor for Bartonella infection.

142 the diagnostic and therapeutic management of Bartonella infection.

143 tive diagnostic method for identification of Bartonella infections in humans and have utility in Bart

144 Diagnosis of Bartonella infections is hampered by the slow, fastidiou

145 at elicit antibody production in response to Bartonella infections, this project was undertaken to id

146 ues are increasingly important in diagnosing Bartonella infections.

147 Here we show that Bartonella inhibits apoptosis of endothelial cells in vi

148 No evidence of infection was seen in Bartonella-inoculated astrocyte cultures.

149 Bartonella is a Gram-negative pathogen that is unique am

150 ltA, 16S rRNA gene, and groEL sequences of a Bartonella isolate obtained from a California ground squ

151 Bartonella isolates associated with human disease and re

152 rphism, sequence, and phylogenetic analyses, Bartonella isolates from a dog with endocarditis, 22 gra

153 ed from the human patient in question and of Bartonella isolates obtained from the following Nevada r

154 However, a specific blood culture for Bartonella isolation grew a fastidious, gram-negative or

155 nsation, and hallucinations was persistently Bartonella koehlerae seroreactive and bacteremic.

156 Bartonella koehlerae, a recently described feline Barton

157 er Blattabacterium-like, Solitalea-like, and Bartonella-like symbionts.

158 The Bartonella mitogen was found in bacterial culture supern

159 These data suggest that Bartonella modulation of host or target cell cytokines a

160 intracellular organisms with characteristic Bartonella morphology but identified no ultrastructural

161 species within Methanosarcina, Pseudomonas, Bartonella, Nitrosomonas, Thermotoga, and Aquifex showed

162 sponse, and ELISA testing using other feline Bartonella OMP antigens showed statistically lower optic

163 Very recently, Bartonella organisms have been isolated from large rumin

164 We identified the flea-borne Bartonella parasites infecting sympatric populations of

165 group III consisted of 26 serum samples from Bartonella PCR-negative and IFA-negative dogs, and group

166 group II consisted of 36 serum samples from Bartonella PCR-positive naturally infected dogs, group I

167 Bartonella proteins that elicit an antibody response dur

168 95% confidence interval [CI], 0.293-2.476), Bartonella quintana (OR, 0.425; 95% CI, 0.127-1.479), C.

169 previously identified four highly conserved Bartonella quintana adhesin genes that undergo phase var

170 Here, we report latent infections with Bartonella quintana and a hemotropic Mycoplasma sp. in a

171 Of all bacteria, Bartonella quintana has the highest reported in vitro he

172 saccharide (LPS) and Pap31, a homolog of the Bartonella quintana heme-binding protein A (HbpA), defin

173 necessary to characterize the risk of human Bartonella quintana infection following cat bites.

174 Bartonella quintana is a fastidious, gram-negative, rod-

175 Bartonella quintana is a gram-negative agent of trench f

176 Bartonella quintana is a vector-borne bacterial pathogen

177 The bacterial pathogen Bartonella quintana is passed between humans by body lic

178 family of hemin-binding proteins (Hbp's) of Bartonella quintana that bind hemin on the outer surface

179 We report here the detection of Bartonella quintana, after putative bite transmission, i

180 serum were negative for Bartonella henselae, Bartonella quintana, and B. bacilliformis.

181 DNA amplification of biopsy tissue revealed Bartonella quintana, and Bartonella serologies were subs

182 d to simultaneously detect and differentiate Bartonella quintana, Bartonella henselae, and Coxiella b

183 A BafA homolog from a related pathogen, Bartonella quintana, is also functional.

184 ily of proteins from Bartonella henselae and Bartonella quintana, respectively.

185 Bartonella quintana, the agent of trench fever and a cau

186 Bartonella quintana, the agent of trench fever and an et

187 as cultured in the 1960s and reclassified as Bartonella quintana; it was also found to cause endocard

188 The genes were termed brpA to -C (bartonella repeat protein) and bore significant similari

189 ns can be coinfected with various Ehrlichia, Bartonella, Rickettsia, and Babesia species.

190 This study reports the occurrence of "Bartonella rochalimae" in Europe and the presence of Bar

191 first case of canine endocarditis caused by "Bartonella rochalimae" is reported.

192 We propose that Bartonella's antiapoptotic mechanism accounts at least i

193 ree strains and placed them within the genus Bartonella separately from previously described species.

194 psy tissue revealed Bartonella quintana, and Bartonella serologies were subsequently noted to be posi

195 serological testing (i.e., Q fever serology, Bartonella serology) in culture-negative cases.

196 We challenged cats transfused with anti-Bartonella serum and kittens born to antibody-positive q

197 DNA sequencing evidence of a potentially new Bartonella sp. infecting dogs in Greece and Italy.

198 After a 1-month incubation period, a Bartonella sp. was isolated on a 5% rabbit blood agar pl

199 r bacterial, viral and parasitic agents like Bartonella sp., Phleboviruses and Leishmania spp., respe

200 We detected infection with a Bartonella species (B. henselae or B. vinsonii subsp. be

201 Three strains of a novel Bartonella species (Bartonella tamiae) were isolated fro

202 . elizabethae should be added to the list of Bartonella species (i.e., B. vinsonii subsp. berkhoffii,

203 species are a reservoir host for pathogenic Bartonella species and are consistent with a hypothesize

204 ergoing coronary angiography for evidence of Bartonella species and Coxiella burnetii infection.

205 srA sequences was sufficient to discriminate Bartonella species and provided phylogenetic data consis

206 strain and to several known human-pathogenic Bartonella species and subspecies: Bartonella henselae,

207 t advance in the genetic manipulation of all Bartonella species and, combined with the animal model t

208 Most known Bartonella species are arthropod borne.

209 Bartonella species are gram-negative, emerging bacterial

210 Bartonella species cause serious human infections global

211 le were identified as Bartonella bovis, both Bartonella species commonly found in wild and domestic r

212 Bartonella species constitute emerging, vector-borne, in

213 pid and reliable method for the detection of Bartonella species DNA in clinical samples.

214 , we investigated the potential use of other Bartonella species for their ability to recapitulate hum

215 pecific enough to detect a diverse number of Bartonella species in a wide range of environmental samp

216 cular findings related to the isolation of a Bartonella species in North Carolina beef cattle and the

217 s associated with the molecular detection of Bartonella species in patient samples and indicate that

218 cats supports a potential etiologic role for Bartonella species in several idiopathic disease process

219 al results support perinatal transmission of Bartonella species in this family.

220 voles) in the UK and confirmed that several Bartonella species infect both rodent species.

221 ent with a hypothesized Old World origin for Bartonella species recovered from Rattus species introdu

222 ed strains, the activity is produced only by Bartonella species that are significant human pathogens

223 ngle-step PCR assay to differentiate between Bartonella species was determined with characterized iso

224 Infection with a Bartonella species was implicated in three cases of epis

225 Bartonella species were isolated from the blood of 63 of

226 pable of detecting the diverse repertoire of Bartonella species while maintaining genus specificity h

227 ed by an organism identified as the proposed Bartonella species, "B. washoensis." The organism was is

228 Because of variation in ITS sequences among Bartonella species, a single PCR amplification can be us

229 tys, 20 with a Rickettsia species, 16 with a Bartonella species, and 7 with B. canis.

230 o support cocultures consisting of different Bartonella species, and it facilitated the primary isola

231 resented a previously uncultured and unnamed bartonella species, closely related to B. clarridgeiae a

232 and considerably divergent from other known Bartonella species, confirming their novelty.

233 monstrated specific amplification in over 30 Bartonella species, subspecies, and strains.

234 ulted in a product of a unique size for each Bartonella species, thereby allowing differentiation wit

235 nella koehlerae, a recently described feline Bartonella species, was isolated from two naturally infe

236 refore, it is important to determine if some Bartonella species, which are emerging pathogens, could

237 an uncommon manifestation of infection with Bartonella species.

238 m that supports the growth of at least seven Bartonella species.

239 used as a diagnostic target for detection of Bartonella species.

240 to achieve molecular diagnostic detection of Bartonella species.

241 tration of molecular Koch's postulates for a Bartonella species.

242 d the fur gene and flanking regions of three Bartonella species.

243 es to the identification of human-pathogenic Bartonella species.

244 on and differentiation of medically relevant Bartonella species.

245 on and differentiation of medically relevant Bartonella species.

246 e slow, fastidious growth characteristics of Bartonella species.

247 dogs were more likely to be seroreactive to Bartonella spp.

248 ty was observed with antiserum against other Bartonella spp.

249 (8.4%), Anaplasma phagocytophila (1.9%), and Bartonella spp. (34.5%).

250 Bartonella spp. are etiological agents of life-threateni

251 Bartonella spp. are known to induce vasoproliferative tu

252 e performed to clarify the potential role of Bartonella spp. as a cause of chronic neurological and n

253 lished reports, support a potential role for Bartonella spp. as a cause of epistaxis in dogs and pote

254 h as PCR may help to implicate a spectrum of Bartonella spp. as a cause of or a cofactor in chronic c

255 Several Bartonella spp. have been found to cause culture-negativ

256 evalence of bacteremia and seroreactivity to Bartonella spp. in gray foxes suggests that they may act

257 orting concurrent infection with one or more Bartonella spp. in more than one family member; however,

258 ining changes in prevalence and abundance of Bartonella spp. infection in rodents and their flea vect

259 It is of clinical relevance that Bartonella spp. may adversely influence human reproducti

260 had reciprocal titers of antibodies against Bartonella spp. of > or =64.

261 s experimentally and naturally infected with Bartonella spp. other than B. henselae Additional resear

262 hern blots indicate that all five pathogenic Bartonella spp. possess hbpA homologs.

263 ts (20.8%) were PCR positive for one or more Bartonella spp. using the BAPGM platform.

264 virus, and yellow fever virus), 8 bacteria (Bartonella spp., Brucella spp., Coxiella burnetii, Lepto

265 adult beagles experimentally inoculated with Bartonella spp., group II consisted of 36 serum samples

266 Infections caused by several bacteria (e.g. Bartonella spp., Lawsonia intracellularis and Citrobacte

267 Patients with infection from bacteremic Bartonella spp., tested using Bartonella Alphaproteobact

268 ains, which were closely related to a cattle Bartonella strain and to several known human-pathogenic

269 icks, molecular analysis showed a variety of Bartonella strains, which were closely related to a catt

270 tsia typhi also reacted with our recombinant Bartonella SucB.

271 Bartonella suppresses both early and late events in apop

272 lla infections in humans and have utility in Bartonella surveillance studies.

273 Although heme is essential for Bartonella survival, little is known about genes involve

274 Our data showed that Bartonella tamiae demonstrated temperature-dependent gro

275 Three strains of a novel Bartonella species (Bartonella tamiae) were isolated from human patients fro

276 Here, we demonstrate the ability of Bartonella taylorii to cause chronic infection in SCID/B

277 e ticks were more likely to be infected with Bartonella than female ticks (26 versus 12%, P = 0.05).

278 acificus ticks may play an important role in Bartonella transmission among animals and humans.

279 , defaunation represents an elevated risk in Bartonella transmission to humans (bartonellosis).

280 monella, Escherichia, Shigella, Listeria and Bartonella, using published literature.

281 es associated with each rodent host, and the Bartonella variants carried by individual fleas.

282 were host-generalists but the assemblage of Bartonella variants in fleas tended to reflect the assem

283 in fleas tended to reflect the assemblage of Bartonella variants in the host species they were collec

284 This process led to the discovery of a Bartonella vinsonii subsp. arupensis gene encoding a 382

285 We propose the name Bartonella vinsonii subsp. arupensis subsp. nov. as the

286 Immunologic screening of a Bartonella vinsonii subsp. berkhoffii genomic expression

287 In this report, we describe isolation of Bartonella vinsonii subsp. berkhoffii genotype II from a

288 The molecular characterization of a Bartonella vinsonii subsp. berkhoffii genotype III strai

289 la rochalimae" in Europe and the presence of Bartonella vinsonii subsp. berkhoffii genotypes II and I

290 Bartonella vinsonii subsp. berkhoffii was originally iso

291 Bartonella vinsonii subsp. berkhoffii, Bartonella hensel

292 in 12 dogs, of which 11 were seroreactive to Bartonella vinsonii subspecies berkhoffii antigens.

293 emia with fever due to a novel subspecies of Bartonella vinsonii was found in a cattle rancher.

294 hrlichia sp., 16 to Babesia canis, and 25 to Bartonella vinsonii, and 22 seroconverted to Rickettsia

295 om a mouse experimentally infected with live Bartonella was reactive against recombinant SucB, indica

296 We report the first documented case of Bartonella washoensis bacteremia in a dog with mitral va

297 ck protein gene groEL, and 16S rRNA gene) of Bartonella washoensis cultured from the human patient in

298 an with prosthetic valve endocarditis due to Bartonella washoensis The infecting agent was characteri

299 of 38 cattle had antibodies (> or =1:64) to Bartonella weissii (bovine origin) antigens.

300 Structures suggestive of Bartonella were visualized in some Warthin-Starry staine

301 fecal-oral transmission pathway, but not in Bartonella, which use blood-borne transmission pathways.