ライフサイエンスコーパス: C-terminal tail

1 ed S-shaped Myo1c with Neph1 attached to its C-terminal tail.

2 panning regions and a required intracellular C-terminal tail.

3 cies measured to the alpha1S II-III loop and C-terminal tail.

4 ining motifs homologous to the alpha-tubulin C-terminal tail.

5 elices interlinked by three loops and a long C-terminal tail.

6 rdering of a generally disordered 20-residue C-terminal tail.

7 americ N-terminal domain and an unstructured C-terminal tail.

8 residues on a surface patch and the flexible C-terminal tail.

9 tory amino acid residues located in the Cx43 C-terminal tail.

10 wide main pore is physically plugged by the C-terminal tail.

11 nteracted with the inhibitory phosphorylated C-terminal tail.

12 tion with clarin-1 transcript, requiring its C-terminal tail.

13 our-helix bundle fold stabilized by its long C-terminal tail.

14 phosphorylated at four serines in its 18-aa C-terminal tail.

15 ortant of which is the autoinhibition by its C-terminal tail.

16 (K40) or detyrosination of the alpha-tubulin C-terminal tail.

17 9), Ser(350), Ser(357), and Ser(360)) in the C-terminal tail.

18 e PDZ domain configurations and a disordered C-terminal tail.

19 abilized by four disulfide bonds, and a long C-terminal tail.

20 ta and Imp7 chaperone the positively charged C-terminal tail.

21 t and second UBL domains (UBL1-2) within the C-terminal tail.

22 n, and its SH3 domain, which engages the PP1 C-terminal tail.

23 Ric8A: an armadillo-fold core and a flexible C-terminal tail.

24 -stranded RNA-binding domains (dsRBDs) and a C-terminal tail.

25 rs that contained only one tyrosine in their C-terminal tail.

26 ted to extend the Ser65 loop and shorten the C-terminal tail.

27 tor phosphorylation, often at the receptor's C-terminal tail.

28 two G domains together at their unstructured C-terminal tails.

29 wap involving the two N-terminal helices and C-terminal tails.

30 ysical interactions between adjacent channel C-terminal tails.

31 art through electrostatic binding to tubulin C-terminal tails.

32 e domain and intrinsically disordered N- and C-terminal tails.

33 steric interactions between adjacent channel C-terminal tails.

34 been linked to a "tubulin code" in which the C-terminal tail, a region of substantial sequence diverg

35 es a PDZ domain, a BAR domain, and an acidic C-terminal tail (ACT).

36 AE1's C-terminal tail (AE1C) contains multiple potential membr

37 The C-terminal tails also impact the conformational state of

38 s to cognate peptides within their partners' C-terminal tails, analogous to the "safety belt" binding

39 d with increased PTEN phosphorylation in the C-terminal tail and its localization to chromatin.

40 completed by His103 and His105 of the S100A9 C-terminal tail and previously identified as the high-af

41 onstrate that spinophilin interacts with the C-terminal tail and second intracellular loop of Group I

42 ons with the H3 alphaN, the H3 tail, the H2A C-terminal tail and stabilizes DNA in the unwrapped conf

43 estriction factor SAMHD1 at either its N- or C-terminal tail and targets it for destruction by the ce

44 protein lacking both the membrane-anchoring C-terminal tail and the intrinsically disordered loop, a

45 phosphorylates a conserved tyrosine in their C-terminal tail, and are activated by the receptor-type

46 nds the large FtsZ globular core rather than C-terminal tail, and the presence of two adjacent pocket

47 central alpha-helix with unstructured N- and C-terminal tails, and binds to the beta1 domain of RNAP.

48 d that the GGxxF and FxFG motifs in the Imp7 C-terminal tail are essential for Imp7:Impbeta dimerizat

49 To determine whether these C-terminal tails are intrinsically disordered regions, w

50 each provide evidence that the EGFR and HER3 C-terminal tails are intrinsically disordered with exten

51 ates in the intrinsically disordered tubulin C-terminal tails, are crucial for the biogenesis and sta

52 on is cell autonomous and is mediated by its C-terminal tail, as only Kif5Aa and chimeric motors cont

53 pend on disulfide formation or reside in the C-terminal tail binding site and cause constitutive C-te

54 we serendipitously discovered that its free C-terminal tail binds PDZ domains (when unphosphorylated

55 that a peptide corresponding to the Atlastin C-terminal tail binds to membranes as a parallel alpha h

56 s showed that the large central loop and the C-terminal tail both reside in the cytoplasm and are sep

57 Our density map reveals the receptor C-terminal tail bound to the Gbeta subunit of the G prot

58 imultaneously bind DNA in the absence of the C-terminal tail, but the tail modulates DNA binding and

59 Src is inhibited via phosphorylation of its C-terminal tail by another kinase, C-terminal Src kinase

60 in which beta5-strand slippage retracts the C-terminal tail by two residues into the Ub core.

61 f the microtubule surface, including tubulin C-terminal tails by CAP-Gly.

62 The C-terminal tail (C-tail) of AGC kinase domains is a high

63 se upon deletion of the non-conserved acidic C-terminal tail (C-tail) of the CTDs has been reported.

64 ain, followed by an acidic region (AR) and a C-terminal tail (C-tail) that have been shown to regulat

65 ly disordered linkers (IDLs) within the four C-terminal tails connected to the ssDNA binding domains.

66 interact strongly with beta-arrestins via a C-terminal tail containing clusters of serine/threonine

67 chemical characterization suggested that the C-terminal tail containing the GG motif interacts with t

68 The extramembrane C-terminal tail contains a completely conserved proline,

69 II is associated with phosphorylation of its C-terminal tail (CTD).

70 ulin, or whether proteolytic cleavage of the C-terminal tail (CTT) of alpha- and beta-tubulin, the lo

71 vation of arginine relative to lysine in the C-terminal tail (CTT) of HIV-1 envelope (Env).

72 by eliminating the last two residues of the C-terminal tail (CTT) of Rps16, believed to contact init

73 We investigated the role of the C-terminal tail (CTT) of SecA in nascent polypeptide rec

74 initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leadin

75 haromyces cerevisiae), has a long protruding C-terminal tail (CTT) that extends towards the mRNA clef

76 dergoes regulated cleavage that releases its C-terminal tail (CTT), which translocates to the nucleus

77 s a well-folded core domain and a disordered C-terminal tail (CTT).

78 Most SecA proteins contain a long C-terminal tail (CTT).

79 g to GCN2; however, the conserved 14-residue C-terminal tails (CTTs) in the P1 and P2 P-stalk protein

80 and/or glutamate residues to the disordered C-terminal tails (CTTs) of tubulin.

81 Mutations in the C-terminal tail decrease fusion activity in vitro, but n

82 The C-terminal tails demonstrate more rapid deuterium exchan

83 by tethering multiple Stim1 domains to Orai1 C-terminal tail, demonstrating that alpha-SNAP regulates

84 es clustered in two separable regions of the C-terminal tail, designated cluster 1 (Thr(347), Thr(349

85 This C-terminal tail displays the binding site for partner pr

86 However, when the C-terminal tail domain (CTD) is deleted, the majority of

87 n our current studies, we characterized a gB C-terminal tail domain (CTD) mutant truncated at amino a

88 Here we have examined the role of the C-terminal tail domain of Cin8 in regulating directional

89 on-catalytic domain of separase binds to the C-terminal tail domain of three homologs of the centrome

90 onsists of an N-terminal 'head' domain and a C-terminal tail domain that contains several predicted c

91 metavinculin-specific insert is part of the C-terminal tail domain, the actin-binding site of both i

92 core domain and an intrinsically disordered C-terminal tail domain.

93 The intrinsically disordered eIF1A C-terminal tail (eIF1A-CTT) binds to eIF5B Domain-4 (eIF

94 ), while the other two selectively truncated C-terminal tails encoded by either exon 4 (mE4M mice) or

95 equent large displacements of the regulatory C-terminal tail expose the substrate-binding surface and

96 yers with its flexible N-terminal domain and C-terminal tail exposed to the outside.

97 chimeric M2 receptor with nonphosphorylated C-terminal tail failed to activate Src.

98 runcated ACTN4 mutant 1-890, which lacks the C-terminal tail, fails to rescue the amoeboidal morpholo

99 nal propeller needs to be able to engage the C-terminal tail for vesicle clustering to occur.

100 decoupled, with the intrinsically disordered C-terminal tail fragment of ODC being required only for

101 x by the dominant negative membrane-anchored C-terminal tail fragment of PC1 elevated NHA2.

102 that WASP displaces the autoinhibitory Arp3 C-terminal tail from a hydrophobic groove at Arp3's barb

103 nding at this unique site shields the S100A9 C-terminal tail from proteolytic degradation by proteina

104 on event within the last few residues of the C-terminal tail generates a posttranslational modificati

105 trast, other AKAP79-signaling components and C-terminal tail GluA1 phosphorylation sites exhibited a

106 Thus, our data suggest that C-terminal tails harbor crucial signals for both the ins

107 intermolecular NTD-CTD interactions, and the C-terminal tail, have substantial static or dynamical di

108 the anionic semiquinone (ASQ) restructures a C-terminal tail helix (CTT) that otherwise inhibits inte

109 dynamics simulations suggests that the Ric8A C-terminal tail helps organize the GTP-binding site of G

110 phosphorylated on Yck consensus sites in its C-terminal tail in a Yck-dependent manner and that this

111 olved the high-resolution structure of DISC1 C-terminal tail in complex with its binding domain of Nd

112 a structural foundation for the role of the C-terminal tail in GPCR signaling, and of Gbeta as scaff

113 plained by the lack of an acidic, disordered C-terminal tail in human mtSSB protein.

114 tation of nanoscale motion at the tip of the C-terminal tail in the phosphomimic S339D/S340D mutant.

115 atively simple architecture, synthesize such C-terminal tails in the absence of a small ribosomal sub

116 ersely, the interaction of RecQ with the SSB C-terminal tail increases the on-rate of RecQ-DNA bindin

117 a pauses mediated by K-loop/polyglutamylated C-terminal tail interactions, providing further insight

118 Here we demonstrate that the Arp3 C-terminal tail is a structural switch that prevents Arp

119 able lipid bilayers, the requirement for the C-terminal tail is abrogated.

120 We show that the TubZ C-terminal tail is an unstructured domain that fulfills

121 During apoptosis, the C-terminal tail is cleaved by caspase, allowing the rele

122 The function of the C-terminal tail is conserved in human Atlastin.

123 Biochemical analysis shows that the Ric8A C-terminal tail is critical for its stability and functi

124 Their C-terminal tail is especially important in enabling the

125 protein S/TFPI interaction and that the TFPI C-terminal tail is not essential for this enhancement.

126 It contains nine tyrosines in its C-terminal tail, many of which are phosphorylated and bi

127 activity compared with ADAMTS13 lacking its C-terminal tail (MDTCS) or its CUB1-2 domains (WTDeltaCU

128 ed a threonine phosphorylation site within a C-terminal tail motif, which is targeted by the Akt/seru

129 mplex module for PM association found in the C-terminal tail of AAPs.

130 The C-terminal tail of AE1 has an important role in its pola

131 In contrast, the C-terminal tail of alpha-syn is regulated by calcium ion

132 In particular, the role of the amphipathic C-terminal tail of Atlastin is still unknown.

133 These data suggest that the C-terminal tail of Atlastin locally destabilizes bilayer

134 ion occurs when the intrinsically disordered C-terminal tail of beta-spectrin binds the N-terminal ta

135 Kindlin-2 linkage to the C-terminal tail of beta3 completed the outside-in circui

136 ons from random-coil chemical shifts for the C-terminal tail of capsid and SP1, both in the absence a

137 as1-2/I-E-via the type I-E-specific extended C-terminal tail of Cas1-displays intrinsic affinity for

138 lectrostatic interactions between the acidic C-terminal tail of Cdc34 and a feature on SCF called the

139 The C-terminal tail of CENH3 is confirmed to be responsible

140 nesis revealed that a conserved motif in the C-terminal tail of DC2 is critical for assembly into the

141 H2)-SH3-SH2 domains, which interact with the C-terminal tail of DCC, is sufficient to restore netrin-

142 Finally, we provided evidence that the C-terminal tail of DHHC5 can be palmitoylated in respons

143 gulate DOR surface delivery, focusing on the C-terminal tail of DOR that is sufficient for NGF-mediat

144 her these results suggest that, although the C-terminal tail of dSLBP does not contact the RNA, phosp

145 ements of linkage specificity, including the C-terminal tail of E6AP and a hydrophilic surface region

146 mutations reduce autophosphorylation of the C-terminal tail of EGFR and attenuate phosphorylation of

147 IF1A promote scanning, eIF1 and possibly the C-terminal tail of eIF1A must be displaced from the P de

148 uencing revealed a partial truncation in the C-terminal tail of Env that had emerged in the sort; how

149 , highlighting the indispensable role of the C-terminal tail of FAAP20, beyond the compact zinc finge

150 concert with structural elements within the C-terminal tail of FFA4 to allow for the recruitment of

151 Here we describe the crystal structure the C-terminal tail of FGF19 (FGF19(CT)) bound to sKLB and d

152 Here we report that the C-terminal tail of FGF23, a region responsible for KLA b

153 lient-binding region of Hsp90(Ec) and in the C-terminal tail of FtsZ, where many cell-division protei

154 acteria known to interact with the conserved C-terminal tail of FtsZ.

155 e cargo-binding domain was identified in the C-terminal tail of fungal Kinesin heavy chain (KHC).

156 In addition, Gbetagamma interacts with the C-terminal tail of GPR124 and promotes the formation of

157 he nucleic acid binding site of BolA and the C-terminal tail of Grx.

158 The C-terminal tail of H1.2 is critical for the observed eff

159 WP2A does not influence H2A.Z occupancy, the C-terminal tail of H2A.Z is one important mediator to re

160 hemical approaches, we demonstrated that the C-terminal tail of HER3 interacted with the WW domains o

161 germline frameshift mutations involving the C-terminal tail of HIST1H1E, which is a widely expressed

162 virus carrying a truncation deletion of the C-terminal tail of HIV-1 Env glycoprotein 41 (gp41) show

163 The C-terminal tail of hPC2 contains 2 EF hand motifs, but o

164 IRS-1 mediates a direct interaction with the C-terminal tail of IQGAP1.

165 omer contains a lid motif that can clamp the C-terminal tail of its dimeric binding partner against i

166 show that SEPT9 associates directly with the C-terminal tail of KIF17 and interacts preferentially wi

167 Kif5B (kinesin-1) motor domain fused to the C-terminal tail of Kif18A.

168 te with Lck in cells and dephosphorylate the C-terminal tail of Lck, which prevents its adoption of a

169 ed by hyperphosphorylation of the inhibitory C-terminal tail of Lck.

170 teins and by epigenetic modifications of the C-terminal tail of linker histones.

171 A lysine residue (Lys(1112)) at the C-terminal tail of mGluR1 (a member of the group I mGluR

172 etimes required two specific leucines on the C-terminal tail of microR.

173 Both the C-terminal tail of MlaF and the interaction with MlaB ar

174 Our structure also implicates a unique C-terminal tail of MlaF in self-dimerization.

175 etween the C-terminal domain of BRD4 and the C-terminal tail of MLV IN.

176 In sum, these observations suggest that the C-terminal tail of MoaA provides an essential mechanism

177 A phosphorylation cluster in the C-terminal tail of MOPr was identified as a mediator of

178 Phosphorylation of serine 363 on the C-terminal tail of MOR was required and sufficient for a

179 tionally relevant interactions with both the C-terminal tail of Na(v)1.6 and FGF14.

180 studies on Naa60 were unable to resolve the C-terminal tail of Naa60, which is responsible for the o

181 Arg-395 stabilizes the C-terminal tail of NCF4 and the conformation of NCF2 loo

182 we identified a critical RXG sequence in the C-terminal tail of NgBR that is conserved and essential

183 observed that the ultra-long and disordered C-terminal tail of NHERF1 has a type 1 PDZ-binding motif

184 TPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET.

185 viroplasms, highlighting the key role of the C-terminal tail of NSP5 in the formation of replication-

186 We show that the C-terminal tail of NuMA can directly bind to the C termi

187 r this Golgi retention was also found in the C-terminal tail of P/rds and supported the cilia targeti

188 The regions in the C-terminal tail of P/rds are essential for this unconven

189 tein/protein docking, we discovered that the C-terminal tail of p47(phox) is critical for stabilizing

190 purified caspase-3 and -8 could release the C-terminal tail of p53R2.

191 t that this interaction involves the dynamic C-terminal tail of P7, more specifically an acidic clust

192 rted that the VxP motif in the intracellular C-terminal tail of PC1 functions as a CTS in an ADP ribo

193 There is also evidence that the C-terminal tail of PC2 is also cleaved in ELVs.

194 at this peptide is a mimic for the conserved C-terminal tail of PP2A, an important region of the phos

195 and site-specific phospho-Ser/Thr(s) in the C-terminal tail of PTEN.

196 Further modeling of the flexible C-terminal tail of Ric8A indicated that it interacts wit

197 , and proteolytic cleavage or removal of the C-terminal tail of SAA resulted in formation of various-

198 nds on MsRecO interaction with the conserved C-terminal tail of single-stranded (ss) DNA-binding prot

199 The structure reveals that the C-terminal tail of STING adopts a beta-strand-like confo

200 that a conserved PLPLRT/SD motif within the C-terminal tail of STING mediates the recruitment and ac

201 required for RV-A16 replication, nor was the C-terminal tail of STING that mediates IRF3 signaling.

202 of naturally occurring protease sites in the C-terminal tail of SUMO proteins.

203 himeric beta(2)-adrenergic receptor with the C-terminal tail of the arginine vasopressin type 2 recep

204 rmed a high-affinity interaction between the C-terminal tail of the beta1a and RyR1.

205 ta1a490-524) corresponding to the 35-residue C-terminal tail of the beta1a subunit.

206 e we engineer phosphorylation sites into the C-terminal tail of the beta2-adrenoceptor (beta2AR) and

207 fied two phosphorylation sites at the distal C-terminal tail of the chemokine receptor CXCR4, but wer

208 The C-terminal tail of the Drosophila formin Cappuccino (Cap

209 The approximately 230-residue C-terminal tail of the epidermal growth factor receptor

210 RE domain directly binds to the proline-rich C-terminal tail of the essential snRNP core proteins SmN

211 the indel in GPRC6A generates a loss of the C-terminal tail of the Gprca protein.

212 Phosphorylation of residues in the C-terminal tail of the micro-opioid receptor (MOPr) is t

213 The glycan binding site and the novel C-terminal tail of the mutant CALR proteins were require

214 r the interaction with arrestin-3 within the C-terminal tail of the receptor.

215 the SAM-binding site, whereas the conserved C-terminal tail of the second monomer provides residues

216 that mediates critical interactions with the C-terminal tail of the spliceosomal SmN/B/B' proteins in

217 live cells to identify a short motif in the C-terminal tail of the TRPV1 subunit that governs channe

218 taarr1 in complex with only a phosphorylated C-terminal tail of the vasopressin 2 receptor activates

219 ate the role of the intrinsically disordered C-terminal tail of the XRCC4-like factor (XLF), a critic

220 The distal segment of the C-terminal tail of this kinase interacts with, and block

221 xpression of a short segment within the very C-terminal tail of TRIM56 inhibited the replication of i

222 lular integrin alphaVbeta3 binds RKRK at the C-terminal tail of tropoelastin.

223 have used this microarray to interrogate the C-terminal tails of a small group of candidate proteins

224 n of EML4 mediated its binding to the acidic C-terminal tails of alpha- and beta-tubulin on the micro

225 e direct interaction is mediated through the C-terminal tails of both Dyn2 and alpha-actinin 4, and t

226 The C-terminal tails of CysE and CdiA-CT each insert into th

227 The conserved C-terminal tails of GroEL are thus important for protein

228 We show that the flexible C-terminal tails of Mtf1 and TFB2M play a crucial role i

229 and structure-function analyses to truncate C-terminal tails of SYP-5/6, we provide evidence support

230 apping cryo-EM experiments revealed that the C-terminal tails of the H1 isoforms mainly controlled th

231 These PTMs often occur on the C-terminal tails of the microtubule tracks, act as molec

232 y because of the interaction with the acidic C-terminal tails of the tubulin monomers.

233 microtubule binding was not dependent on the C-terminal tails of tubulin.

234 (PKA)-targeted site within its intracellular C-terminal tail, often in conjunction with protein kinas

235 d, a construct composed of the B box and the C-terminal tail only bent DNA at higher protein concentr

236 rsely, the overexpression of a competing CD9 C-terminal tail peptide in REH cytoplasm decreased RAC1

237 next generation sequencing, we show that the C-terminal tail peptide region of MLV IN is important fo

238 that this requires the unstructured anionic C-terminal tail peptides found on both alpha- and beta-t

239 extension of HMO1 as truncation of the HMO1 C-terminal tail phenocopies hmo1 deletion.

240 ructural understanding of PTEN regulation by C-terminal tail phosphorylation, we used protein semisyn

241 p47(phox) C-terminal tail plays a key role in stabilizing intramol

242 Leu(496)-Leu(500)-Trp(503) within the beta1a C-terminal tail plays a nonessential role in the bidirec

243 ct kinesin motor cargo delivery, and include C-terminal tail polyglutamylation important for KIF1A ca

244 1A motility and response to perturbations in C-terminal tail polyglutamylation is underexplored.

245 modifications of the KIF1A K-loop or tubulin C-terminal tail polyglutamylation reduced KIF1A pausing

246 ing in vitro enzyme assays, we show that the C-terminal tail portion of these peptides is dispensable

247 Rather, deletion of a 63-residue-long C-terminal-tail portion of TRIM56 abrogated the antivira

248 two trimer-of-dimer discs stabilized by the C-terminal tails, possibly through tail-to-tail interact

249 n-treated cardiomyocytes) displays decreased C-terminal tail priming-site phosphorylation, increased

250 inal tail and the adjacent SAM domain or the C-terminal tail proceeding the HD domain are targeted by

251 Polyglutamylation of the tubulin C-terminal tail recruits spastin to microtubules and mod

252 nstructured segment in Nup53 and show that a C-terminal tail region binds to a putative helical fragm

253 The plastid-specific C-terminal tail region of cpSRP54 plays a crucial role i

254 The C-terminal tail region of human heme oxygenase-2 (HO2) c

255 merization and reveal a critical role of the C-terminal tail region of IN in higher order oligomeriza

256 on dimer formation; however deletion of the C-terminal tail region prevented dimer formation in vivo

257 ound predicted to bind to PC2 in the PC1:PC2 C-terminal tail region with helix:helix interaction.

258 ne knot (ICK) backbone region and a flexible C-terminal tail region, similar to previously described

259 We further showed that the N- and C-terminal "tail" regions of the peptide are important f

260 We propose that Cu binding to the Ctr1 C-terminal tail regulates Cu transport into the cytoplas

261 nal tail binding site and cause constitutive C-terminal tail release and polymerization.

262 Phosphorylation was detected at rhodopsin C-terminal tail residues T336 and S338.

263 nding domain, residues 1-177, and a flexible C-terminal "tail", residues 178-261.

264 Removing the C-terminal tail resulted in a protein that bent DNA to a

265 R with COPI, via atypical COPI motifs on the C-terminal tail, retain DOR in the Golgi.

266 We propose a model in which the HMGB1 C-terminal tail serves as an intramolecular damper that

267 er/Thr residues (amino acids 380-385) on the C-terminal tail serves to alter the conformational state

268 e N-terminal 75% of apoA-I, and its flexible C-terminal tail suggest the propagation of structural pe

269 mulated the nuclear translocation of the PC1 C-terminal tail/TAZ (PC1-CTT/TAZ) complex, leading to in

270 Our data supports a model in which a single C-terminal tail tethers XLF to Ku, while allowing XLF to

271 CpaB contains a C-terminal tail that appears to block access to the CpaA

272 nsposition target site and an accordion-like C-terminal tail that elongates and contracts to help to

273 M013 also has a unique 33-residue C-terminal tail that follows the N-terminal PYD, and it

274 ike JAZ8, however, JAZ13 contains a Ser-rich C-terminal tail that is a site for phosphorylation.

275 regulated by a conformational change in the C-terminal tail that leads to creation of an enlarged bi

276 esses a unique, structurally uncharacterized C-terminal tail that plays an important role in autophos

277 o unique features as follows: the first is a C-terminal tail that stabilizes the ultimate four HEAT r

278 of the 5-HT3A subunit, but not on the P2X2R C-terminal tail that triggers the functional cross-inhib

279 dentify activities for the highly basic Rrp6 C-terminal tail that we term the 'lasso' because it bind

280 XRCC4 and XLF both include disordered C-terminal tails that are functionally dispensable in is

281 ,8-dihydroneopterin aldolase (Mt-FolB), have C-terminal tails that could also interact with Mt-Enc.

282 intrinsically disordered, negatively charged C-terminal tails that interact with microtubule-binding

283 that Cingulin directly binds to microtubule C-terminal tails through electrostatic interactions.

284 KIF1A initially interacts with microtubule C-terminal tails through its K-loop, a positively charge

285 g region (EF) or two Arg residues within the C-terminal tail (TL).

286 osphorylation disrupts H-bonds that link the C-terminal tail to the autoinhibitory region (AIR) and t

287 ic states and Ca(2+)-binding profiles in the C-terminal tail using biophysical approaches.

288 Evaluation of defined SmpB C-terminal tail variants highlighted the importance of e

289 vivo effects of missense mutation of DISC1's C-terminal tail, we tested mice carrying mutation D453G

290 minus to the II-III and III-IV loops and the C-terminal tail were significantly lower, thus suggestin

291 to modify aberrant translation products with C-terminal tails which assist with RQC-mediated protein

292 distinct structural feature, the protruding C-terminal tail, which appears in both the mutant and wi

293 man STING homodimer and release of the STING C-terminal tail, which exposes a polymerization interfac

294 ight polymers of FtsZ constructs lacking the C-terminal tail, which is known to provide a flexible te

295 Less is known about the Ku70 C-terminal tail, which lies outside the ring.

296 domain binds to the CK2-phosphorylated XRCC4 C-terminal tail, while LigIV uses its tandem BRCT repeat

297 order interactions appear facilitated by the C-terminal tail, while the polyglutamine forms an amyloi

298 ith G protein and through its phosphorylated C-terminal tail with beta-arrestin.

299 ocalization required interactions of the LHR C-terminal tail with the PDZ protein GAIP-interacting pr

300 ggesting an interaction of exon 7-associated C-terminal tails with beta-arrestin 2 in morphine-induce