ライフサイエンスコーパス: CF

1 CF children presented with higher gingival inflammation

2 CF lung disease is driven by innate immune dysfunction a

3 CF macrophage transferrin receptor 1 (TfR1) was reduced

4 CF macrophages exhibit reduced bacterial killing and inc

5 CF mice also exhibit depression-like behaviors compared

6 CF subjects receiving CFTR modulator therapy showed part

7 CF terminals in the KO were localized more proximally on

8 CF(3)-bicyclic dihydroanthracene derivatives have been s

9 CF(3)DODA-Me showed antiproliferative effects on tumor c

10 CF-related diabetes prevalence, however, steadily increa

11 CF-targeted enDUBs synergistically rescued common (Delta

12 of heteroleptic Fe(HMTO)(RO) [RO=(CH(3) )(2) CF(3) CO, CH(3) (CF(3) )(2) CO, or Ph(CF(3) )(2) CO] pre

13 odology uses an hypervalent iodine(III)-CF(2)CF(3) reagent, and mechanistic investigations are consis

14 ss is accomplished by [(Me(3)P)(4)NiH]N(SO(2)CF(3))(2) in the presence of triflic acid.

15 automated radiosynthesis of octreotide[Trp(2-CF(2)(18)F)] enables in vivo positron emission tomograph

16 e Ln(OTf)(3) complexes (Ln=Nd, Sm; OTf=SO(3) CF(3) ) react with crypt in THF to form the THF-soluble

17 e(HMTO)(RO) [RO=(CH(3) )(2) CF(3) CO, CH(3) (CF(3) )(2) CO, or Ph(CF(3) )(2) CO] prepared in situ sig

18 uring this process and the critical C(sp(3))-CF(3) bond-forming step involves the copper catalyst.

19 ions using a newly developed Rh(2) (S-2-Cl-5-CF(3) TPCP)(4) catalyst.

20 imidazol-2-ylidene; X = (Cl or BArF = {(3,5-(CF(3))(2)C(6)H(5))(4)B}), was isolated by reacting [RGe(

21 In addition, we characterize a panel of 62 CF-causing mutations.

22 In 70 CF patients with early infections, 14 shared strains inf

23 We identified 19,802 CF carriers and matched each carrier with 5 controls.

24 direct and indirect fluoride transfer from a CF(3) anionoid to TMSCF(3) (1) has been elucidated.

25 with establishment of chronic infection in a CF sibling pair.

26 Interestingly, a CF(3)-substituted BODIPY, known for forming J-type aggre

27 at can rapidly convert an NH(2) group into a CF(2) H group would be of great value to medicinal chemi

28 . aeruginosa isolates from teenage and adult CF patients, but not those from young CF patients, are o

29 ere is an urgent requirement to review adult CF health care provision, due to both increasing numbers

30 numbers therefore requiring specialist adult CF care.

31 Although early P. aeruginosa CF infection is thought to reflect acquisition of divers

32 -fluoride elimination of the generated alpha-CF(3) carbanions.

33 Although CF monocytes exhibited proinflammatory features, both mo

34 yclopropylamines bearing CH(2)F, CHF(2), and CF(3) substituents were synthesized by different methods

35 The C-CM and CF-incorporated crackers showed higher total phenolics a

36 ably, patients with CF (F508del/F508del) and CF mice showed a greatly attenuated or absent urinary HC

37 fferent clinical prognostic scores (Liou and CF-ABLE), forced expiratory volume in 1 second (FEV(1)),

38 the laboratory P. aeruginosa strain PAO1 and CF clinical isolates and then assessed differences in ba

39 enzyme function with natural, unnatural and CF(2)-labelled post-translationally modified protein sub

40 a rare case of PALG with hyperopic shift and CFs as initial presentation.

41 mal gland (PALG) causing hyperopic shift and CFs with the new OCT-A technology, getting deeper insigh

42 diazonium cations [CH(3) N(H)N(2) ](+) and [CF(3) N(H)N(2) ](+) were prepared as their low-temperatu

43 e a guide for selecting the most appropriate CF animal model for any given application.

44 Grillo-Ardila CF, Torres M, Gaitan HG.

45 esses: (a) ligand-metal charge transfer, (b) CF(3) elimination, and (c) C-C bond rotation processes.

46 requency approximately one-half octave below CF, in accordance with the experimental data.

47 , and IL-1beta could not distinguish between CF and SH but showed positive correlation with GI, PI, a

48 ay inform host-pathogen interactions between CF macrophages and Pa.

49 Wheat flour substitution by CF, GF and RF in bread reduces heat transfer to the doug

50 (trifluoromethyl)-pent-2-en-4-ynes [Ar-C=C-C(CF(3))=CH-CHAr'(Ar")] in good yields.

51 The proximate composition of C-CM and C-CF mostly differed for ash and fiber content as compared

52 Me) and 4-(trifluoromethyl)benzoyl chloride (CF(3)) were studied.

53 parator groups in the same hospital: chronic CF infection, sink drains, sterile site infections and a

54 rk, we show that [Fe(II)(Me(3)NTB)(CH(3)CN)](CF(3)SO(3))(2) (Me(3)NTB = tris((1-methyl-1H-benzo[d]imi

55 as well as a facilitated method for coating CFs with the insulator Parylene-C.

56 ose of the novel triple antibody combination CF-404 (i.e., 1 mg/kg of each component bNAb) delivered

57 We monitor F508del-CFTR, the most common CF-causing variant, and confirm rescue by low temperatur

58 nutrient for bacteria, including the common CF pathogen Pseudomonas aeruginosa (Pa).

59 partial substitution of wheat flour by corn (CF), green banana (GF) and rice flour (RF), at different

60 ry mechanistic experiments reveal that a 'Cu-CF(3)' species is formed during this process and the cri

61 The purpose of this study was to define CF heterogeneity during ventricular remodeling and the u

62 rries the common human Phe508del (DeltaF508) CF transmembrane conductance regulator (CFTR) mutation,

63 the structural effects of a patient-derived CF-phenotypic mutation, E217G, located in the loop regio

64 BB = 4,4'-di(4-benzoato)-2,2'-bipyridine; dF(CF(3))ppy = 2-(2,4-difluorophenyl)-5-(trifluoromethyl)py

65 units (SBUs) and photosensitizing Ir(DBB)[dF(CF(3))ppy](2)(+) [DBB-Ir-F, DBB = 4,4'-di(4-benzoato)-2,

66 in cranial neural crest cells (cNCCs) during CF closure.

67 rs have been identified that function during CF closure, the molecular and cellular mechanisms mediat

68 rs, were analyzed and their functions during CF closure determined.

69 ity reservoirs, we identified frequent early CF strain sharing which was associated with the presence

70 e luminophoric pincer ligands bearing either CF(3) or (t)Bu moieties on the triazole rings along with

71 OM-31R; 4-CH(3) , CMOM-41R) and the existing CF(3) SO(3) (-) variant CMOM-3S are studied herein.

72 luoride and its application to direct [(18)F]CF(3) incorporation at tryptophan or tyrosine residues u

73 We report a one-step route to [(18)F]CF(3)SO(2)NH(4) from [(18)F]fluoride and its application

74 TATA-binding protein (TBP) and core factor (CF).

75 lity of Life Questionnaire-Child Form (FAQLQ-CF) was administered to children aged 8-12 years, and th

76 The total FAQLQ-CF score of 103 children undergoing OIT improved signifi

77 Carbon fiber (CF) electrodes are thinner and more flexible than typica

78 Purkinje neurons (PNs), the climbing fiber (CF) input provides a signal to parallel fiber (PF) synap

79 llar slices revealed altered climbing fiber (CF)-evoked complex spike generation, as well as increase

80 onists and inhibitors on cardiac fibroblast (CF) phenotype, proliferation, and gene expression using

81 peutic progress in treating cystic fibrosis (CF) airway disease, airway inflammation with associated

82 d primary cultures of human cystic fibrosis (CF) and non-CF airway epithelia.

83 proach for the treatment of cystic fibrosis (CF) and other mucoobstructive diseases.Objectives: To de

84 ations in these genes cause cystic fibrosis (CF) and sickle cell disease (SCD), respectively.

85 Animal models of cystic fibrosis (CF) are essential for investigating disease mechanisms a

86 Patients with cystic fibrosis (CF) do not respond with increased urinary HCO(3) (-) exc

87 hort from the United States Cystic Fibrosis (CF) Foundation Patient Registry to assess whether therap

88 ruginosa from patients with cystic fibrosis (CF) frequently contain mutations in the gene encoding an

89 opment of new therapies for cystic fibrosis (CF) has benefited from therapeutically responsive biomar

90 Most infants with cystic fibrosis (CF) have pancreatic exocrine insufficiency that results

91 Cystic fibrosis (CF) is a genetic disease caused by mutations in the CF t

92 Cystic fibrosis (CF) is a life-threatening autosomal recessive disease, c

93 Cystic fibrosis (CF) is a life-threatening chronic inflammatory disease i

94 Cystic fibrosis (CF) is a monogenic disorder caused by mutations in the C

95 Cystic fibrosis (CF) is characterized by chronic bacterial infections and

96 Cystic fibrosis (CF) lung disease is characterized by an inflammatory res

97 to enter the circulation of cystic fibrosis (CF) patients during chronic infective states has not yet

98 rtunistic lung pathogens of cystic fibrosis (CF) patients.

99 ry disease, particularly in cystic fibrosis (CF) patients.

100 is a common complication of cystic fibrosis (CF) that affects approximately 20% of adolescents and 40

101 The role of epithelial cystic fibrosis (CF) transmembrane conductance regulator (CFTR) chloride

102 d mortality associated with cystic fibrosis (CF), a condition that predisposes patients to chronic lu

103 bserved in patient sputa in cystic fibrosis (CF), and while existing epidemiology indicates that pati

104 Conclusion In patients with cystic fibrosis (CF), automated quantification of lung MRI high-signal-in

105 nas aeruginosa infection in cystic fibrosis (CF), non-CF bronchiectasis (BE), and chronic obstructive

106 Background In patients with cystic fibrosis (CF), pulmonary structures with high MRI T2 signal intens

107 Background In cystic fibrosis (CF), recurrent imaging and pulmonary function tests (PFT

108 recessive diseases, such as cystic fibrosis (CF), require inheritance of 2 mutated genes.

109 infections in children with Cystic Fibrosis (CF), suggesting these isolates may have been acquired fr

110 eas CFTR mutations underlie cystic fibrosis (CF).

111 long QT syndrome (LQT) and cystic fibrosis (CF).

112 infections in children with cystic fibrosis (CF).

113 rotoxicity in children with Cystic Fibrosis (CF).

114 We find CF experiments do mitigate some effects of gas-phase wal

115 nked immunoassay (EIA), complement fixation (CF) and immunodiffusion (IMDF).

116 h as cactus mucilage (CM) and cladode flour (CF) for producing gluten-free snacks.

117 Increasingly, however, continuous flow (CF) mode is being used, in which reactants and products

118 Chorioretinal fold (CFs) is a rare condition resulting from undulations in t

119 f this review, several undeveloped areas for CF(3)CHN(2) are outlined, based on the overseen preceden

120 ratios for each condition were computed for CF carriers relative to controls.

121 Newborn screening for CF has enabled earlier diagnosis, nutritional interventi

122 everity, and it improved after treatment for CF exacerbation.

123 t PGD97 may be used as a novel treatment for CF, either as a single agent or in combination with smal

124 severe-intensity threshold (critical force; CF) remain unclear.

125 explaining 71% of the all-ion fragmentation (CF(2))(n) related fragments.

126 first year of treatment following the French CF Learning Society's recommendations.Measurements and M

127 r when solutions reached the SFOAE-frequency CF region.

128 r between a tone's characteristic frequency (CF) place and within one octave basal of the CF.

129 quency (called the characteristic frequency, CF).

130 rimary bronchial epithelial (hBE) cells from CF patients with the mutation.

131 9 N; P < 0.001) to levels not different from CF (276 +/- 55 N). These data suggest that CF reflects a

132 Human blood monocytes were isolated from CF (F508del/F508del) and non-CF persons and derived into

133 at a subset of A. xylosoxidans isolates from CF patients induce cytotoxicity in macrophages, suggesti

134 irway basal stem cells (UABCs) obtained from CF patients.

135 not improve clearance of mucus strands from CF airways.

136 The deuteriodifluoromethyl group (CF(2) D) represents a challenging functional group due t

137 The difluoromethyl group (CF(2) H) is considered to be a lipophilic and metabolica

138 Nine congeners are >=(CF(2))(7) Distinct chemical formulas and structures, as

139 tasets characterizing transcription in human CF vs. non-CF samples from airway and whole blood.

140 and suggest feasibility of an in vivo human CF urine test to validate drug efficacy.

141 methodology uses an hypervalent iodine(III)-CF(2)CF(3) reagent, and mechanistic investigations are c

142 ylase that regulates tubulin acetylation, in CF mice restores growth and inflammatory phenotypes to w

143 lling of B. cenocepacia and P. aeruginosa in CF MDMs in a dose-dependent manner.

144 demonstrated that microtubule alterations in CF are linked to a number of CF phenotypes including gro

145 , we demonstrated that BPI autoreactivity in CF patient sera exhibits high avidity.

146 itical thromboinflammatory effector cells in CF lung disease.

147 ontribution to divergent clinical courses in CF.

148 d contribute to dysregulated host defense in CF lung disease.

149 tudy, the hypothesis that Hdac6 depletion in CF mice would impact behaviors since Hda6 inhibition has

150 A was nearly an order of magnitude higher in CF patients than in healthy subjects (p = 8.0x10(-3)).

151 tilation inhomogeneity and hyperinflation in CF compared with PFT.

152 and calcium flux, and reduced lung injury in CF mice after intratracheal LPS or Pseudomonas aeruginos

153 ndicate a belief that SOA yields measured in CF chambers are not affected by gas-phase wall losses (G

154 Neutrophils were the most prevalent in CF, with a dominant immature proinflammatory archetype.

155 control policy for the management of risk in CF patients.

156 dative stress, consistent with a key role in CF lung disease.

157 rnal nucleophilicity of aryl substituents in CF(3)-pentenynes and external nucleophilicity of aromati

158 KC activation attenuates matrix synthesis in CFs.

159 s are further intramolecularly cyclized into CF(3)-bicyclic dihydroanthracene derivatives ("helicopte

160 Though KO CFs evoked larger amplitude EPSCs, the charge transfer w

161 oroanion generation, (13)C/(2)H KIEs, LFERs, CF(2) transfer efficiency and selectivity, the effect of

162 (PnPh(3)) as monodentate ancillary ligands ([CF(3)/Pn] or [(t)Bu/Pn], respectively) have been investi

163 hly proliferative Periostin (Postn)+ lineage CFs were found from postnatal day 1 (P1) to P11 but were

164 When activated with LPS, CF macrophage expressed reduced ferroportin (Fpn).

165 -wide efficiency as indicated by annual mean CF.

166 nd gene expression using primary adult mouse CFs, which spontaneously transdifferentiate into myofibr

167 Electron microscopy demonstrated that mutant CF terminals had twice as many vesicle release sites, pr

168 fonyl group adopting a sharp kink, and its N-CF(3)-phenyl substituted piperazine group reaching out t

169 F508) and pharmacotherapy-resistant (N1303K) CF mutations when combined with the US Food and Drug Adm

170 ltures of human cystic fibrosis (CF) and non-CF airway epithelia.

171 or the treatment of patients with CF and non-CF mucoobstructive diseases.

172 e isolated from CF (F508del/F508del) and non-CF persons and derived into macrophages (MDMs).

173 inosa infection in cystic fibrosis (CF), non-CF bronchiectasis (BE), and chronic obstructive pulmonar

174 acterizing transcription in human CF vs. non-CF samples from airway and whole blood.

175 ing on a validated and published nongenetic, CF-like sheep model, ewes inhaled CFTR(inh)172 and neutr

176 When metalated with palladium, o-CF(2)H-functionalized 1,10-phenanthroline provides highl

177 oromethyl-3,11-dioxoolean-1,12-dien-30-oate (CF(3)DODA-Me), a potent anticancer agent, were studied o

178 at the Si(II) atom with [H(OEt(2))(2)][Al{OC(CF(3))(3)}(4)] induces formal oxidation, and the compoun

179 tion is also expected to change, with 36% of CF adults being over 40 in 2030, versus 21% in 2017.

180 low generation, and crystalline analogues of CF(3)CHN(2) were developed during the past decade and ha

181 amplification extended two octaves apical of CF, which highlights that different vibratory motions pr

182 ion typically extended ~1.5 octaves basal of CF, and the data are consistent with coherent reflection

183 E components originate many octaves basal of CF.

184 al difluoro motif as a hybrid bioisostere of CF(3) and Et (BITE) in a series of modified barbiturate

185 ision therapies addressing the root cause of CF disease.

186 ingle-cell transcriptome characterization of CF sputum.Objectives: To define the transcriptional prof

187 CF addition, except for the darker color of CF-supplemented crackers.

188 ulmonary manifestations and comorbidities of CF.

189 nostic treatment for a major complication of CF.

190 l as increased amplitude and faster decay of CF-evoked EPSCs.

191 To advance the rational design of CF therapies, it is important to elucidate how mutationa

192 is of immune function and the development of CF lung disease.Methods: We performed single-cell RNA se

193 telet activation, which is a major driver of CF lung inflammation and impaired bacterial clearance.

194 Failure of CF closure results in colobomas.

195 mural than standard CF lesions with >20 g of CF in both groups (59.1% versus 7.7%; P<0.001 and 60.0%

196 the standard CF catheter-even with >20 g of CF-in both normal (983.1+/-905.8 versus 461.9+/-178.3 mm

197 scoveries that change the natural history of CF lung disease.

198 attributed to the more proximal location of CF terminals.

199 The mechanism of CF(2) transfer from TMSCF(3) (1), mediated by TBAT (2-12

200 to classify the existing reactivity modes of CF(3)CHN(2) and to systematically analyze the correspond

201 alterations in CF are linked to a number of CF phenotypes including growth regulation and inflammato

202 FAA partition coefficients and the number of CF(n) units indicates that OC is a good predictor of PFA

203 The age at onset of CF-related diabetes (CFRD) (marked by clinical diagnosis

204 iagnosis, and treatment for a broad range of CF carrier-related conditions.

205 Both rat models revealed a range of CF manifestations, including reduced survival, intestina

206 arriers are at increased risk for a range of CF-related conditions.

207 reveal distinct PKC-dependent regulation of CF transdifferentiation and proliferation and suggest th

208 d understanding of both the altered state of CF cells and the mechanisms of existing rescue strategie

209 Available in vitro systems of CF are also described and can offer a useful alternative

210 or heteroaromatic CH groups with N atoms or CF, CMe, or COH groups).

211 ysical properties were not impacted by CM or CF addition, except for the darker color of CF-supplemen

212 e transmetalation of [(XPhos)ArPdBr] (Ar = p-CF(3)-C(6)H(4)) with a model sulfoxonium ylide was obser

213 sequencing on isolates from early pediatric CF pulmonary infections and from comparator groups in th

214 chanism for local coincident detection of PF-CF activity.

215 ear Ca(2+) signals associated with paired PF-CF synaptic activity.

216 ) )(2) CF(3) CO, CH(3) (CF(3) )(2) CO, or Ph(CF(3) )(2) CO] prepared in situ significantly increases

217 Thus, postnatal CFs are heterogeneous and include a transient proliferat

218 A beta-proline CF(3)-tripeptide with alternating absolute chirality bet

219 A decrease in PWV(CF) , PWV(CR) , SBP and DBP (-25%, -17%, -4% and -8%, re

220 Central (carotid-femoral artery PWV, PWV(CF) ) and peripheral (carotid-radial artery PWV, PWV(CR)

221 and the underlying mechanisms that regulate CF function.

222 ons were more often transmural than standard CF lesions with >20 g of CF in both groups (59.1% versus

223 uced larger lesion volumes than the standard CF catheter-even with >20 g of CF-in both normal (983.1+

224 hyl-alkyl)thiophenes in Bronsted superacids (CF(3)SO(3)H, FSO(3)H) gave rise to short-lived and react

225 ation and neuronal development, while Tcf21+ CFs differentially express genes related to ECM maturati

226 Ten CF (aged 3 to 12 years) and 10 systemically healthy (SH)

227 However, some studies indicate that CF carriers are at increased risk for some conditions as

228 m CF (276 +/- 55 N). These data suggest that CF reflects an oxygen-delivery-dependent balance between

229 The CF clones Strain B and Clone C were present.

230 The CF rat models presented herein will prove useful for lon

231 The CF(3)Boc-group that caps the P3 amino moiety was discove

232 nes have a stereochemistry such that all the CF(3) groups are on the same face of the cyclohexyl ring

233 ction between the NH(2) groups on DA and the CF(2) groups on PVDF is responsible for aligning the PVD

234 Iron is elevated in the CF lung and is a critical nutrient for bacteria, includi

235 of a pathogenic or inflammatory role in the CF lung.

236 s of early P. aeruginosa colonization in the CF lung.

237 ecessive disease, caused by mutations in the CF transmembrane conductance regulator (CFTR) chloride c

238 a genetic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, resu

239 0 cm(-1) compared to the same stretch in the CF(3) analogue, indicating a significantly stronger HB i

240 ditionally, the synthetic versatility of the CF(2)Br intermediates was showcased through functionaliz

241 hough the electron-withdrawing nature of the CF(3) group should facilitate deprotonation of adjacent

242 The exceptional ability of the CF(3) moiety to prevent in vivo metabolism as well as im

243 n the direct photochemical reactivity of the CF(3) moiety.

244 CF) place and within one octave basal of the CF.

245 occurring only when PF activity precedes the CF input.

246 ns that arise as P. aeruginosa adapts to the CF lung abrogate T6SS activity, making P. aeruginosa and

247 ropic glutamate receptors (mGluR1s) when the CF input is delayed by 100-150 ms from the first PF inpu

248 inear Ca(2+) transients, associated with the CF synaptic potential and colocalized with the PF Ca(2+)

249 removal of the tumor partially resolved the CFs and contributes to impressive visual acuity recovery

250 the H-bonding interaction strength for the -CF(2)H group (~3 kcal/mol).

251 que reductive and base compatibility of the -CF(2)H hydrogen bond donor group.

252 In the excess of TfOH, these CF(3)-pentenynes are further intramolecularly cyclized i

253 have provided significant health benefits to CF patients.

254 sed for some conditions previously linked to CF carriers (e.g., pancreatitis, male infertility, bronc

255 Comparing SERF to CF ablation, the SERF catheter produced larger lesion vo

256 thoxy (-OCH(3)) as well as trifluoromethyl (-CF(3)) in the 2 and 3 position as potential candidates f

257 s and elucidate the role of the triterpenoid CF(3)DODA-Me in abrogating several of these tumor-promot

258 ecessity for syn-pyramidalization of the two CF(2) groups in the 4 + 2 transition state.

259 We used UK CF Registry data to project the number of patients aged

260 ect of the peripheral substituent ((t)Bu vs. CF(3), respectively) and its influence on the bonding, c

261 hiles including CO(2) and aldehydes, whereas CF(3) radical addition furnishes a wide range of gem-dif

262 Our goal was to determine whether CF carriers are at increased risk for a range of CF-rela

263 0% of adolescents and 40%-50% of adults with CF.

264 to address the basic defects associated with CF-causing mutations, partially restoring the CFTR funct

265 sed risk for some conditions associated with CF.

266 Children with CF had significantly higher BOP scores (P = 0.001) and c

267 ions and lung disease in young children with CF.Methods: Longitudinal data on 330 children participat

268 ductal cells and frequently coexpressed with CF transmembrane conductance regulator (CFTR) along with

269 .65, P < .001), whereas the correlation with CF-ABLE score was weaker (R = 0.28 to 0.38, P = .005 to

270 After removing individuals diagnosed with CF and SCD, we assessed heterozygosity effects at our le

271 or these infants, allowing most infants with CF to achieve their weight goals by 12 months of age(1).

272 rection of low linear growth in infants with CF.

273 MDMs were infected with CF clinical isolates of B. cenocepacia and P. aeruginosa

274 27 years]; six men) and 12 participants with CF (median age, 18 years [age range, 9-40 years]; eight

275 Participants with CF also underwent pulmonary function tests the same day.

276 rics were compared between participants with CF and control participants.

277 rom May 2018 to June 2019, participants with CF and healthy control participants underwent PFTs and f

278 In six participants with CF exacerbation and follow-up after treatment, a decreas

279 Participants with CF exacerbation underwent repeat MRI after their treatme

280 IQR(N) was higher for participants with CF than for control participants (mean, 0.66 +/- 0.16 vs

281 ll expiration was lower in participants with CF than in control participants (0.34 +/- 0.08 vs 0.39 +

282 lthy individuals and study participants with CF were prospectively enrolled between January 2017 and

283 For participants with CF, MRI metrics were correlated with the standard lung c

284 In participants with CF, T2-weighted HSV or T2-weighted VIP were associated w

285 Notably, patients with CF (F508del/F508del) and CF mice showed a greatly attenu

286 approach for the treatment of patients with CF and non-CF mucoobstructive diseases.

287 that serum and monocytes from patients with CF exhibit an enhanced NLRP3-inflammasome signature with

288 al epithelial (HBE) cells from patients with CF without impacting calcium signaling.

289 explain metabolic alkalosis in patients with CF, and suggest feasibility of an in vivo human CF urine

290 and exacerbation risk in adult patients with CF.Supplemental material is available for this article.S

291 now applicable for up to 90% of people with CF who carry responsive CFTR mutations, including those

292 esise carbene-metal-amide photoemitters with CF(3)-substituted ligands to show sky-blue to deep-blue

293 The reaction of quinolines with CF(3)-ynones resulted in the formation of 1,3-oxazinoqui

294 cing of sputum cells from nine subjects with CF and five healthy control subjects.

295 iven condition increased among subjects with CF, so did the corresponding relative odds for carriers

296 mpared our results with 23,557 subjects with CF, who were also matched with controls; as the relative

297 here TpXPC = tris(para-X-phenyl)corrole (X = CF(3), H, Me, and OCH(3)) and L = pyridine (py), trimeth

298 is(para-X-phenyl)corroles, Re[TpXPC](O) (X = CF(3), H, F, CH(3), and OCH(3)), with elemental chlorine

299 adult CF patients, but not those from young CF patients, are outcompeted by the epidemic Bcc isolate

300 can initiate long-term infections in younger CF patients, Bcc infections only arise in teenagers and