ライフサイエンスコーパス: CFR

1 CFR improved with treatment in the spironolactone group

2 CFR in the left anterior descending coronary artery was

3 CFR is a stronger predictor of cardiovascular mortality

4 CFR simultaneously detects superoxide anion (O(2)(*-)) a

5 CFR was a stronger predictor of cardiovascular mortality

6 CFR was assessed by cardiac positron emission tomography

7 CFR was associated with outcomes independently of angiog

8 CFR was inversely related to parathyroid hormone (PTH) l

9 CFR was lower in PHPT patients than in control subjects

10 CFR was measured as the ratio of maximum flow to baselin

11 CFR was measured by positron emission tomography [N(13)]

12 CFR was not associated with infarct characteristics or c

13 CFR was quantified from stress/rest myocardial blood flo

14 CFR was the highest for Spn meningitis: 12.9% (46/357) i

15 CFR was the ratio of hyperemic to resting diastolic flow

16 CFRs within 30 days and 1 year after an IS declined by 3

17 R was 29.5 (interquartile range: 17.0-55.0), CFR was 1.4 (1.1-2.0), and RRR was 1.7 (1.3-2.3).

18 Age-specific COVID-19 CFRs and age-specific population shares by country.

19 ountries, the observed variation in COVID-19 CFRs is 13 times larger than what would be expected on t

20 o give the metallacyclobutanes CpCo(kappa(2)-CFR(F)CF2CF2-)(PPh2Me) in the first examples of cycloadd

21 as a compliance effort with OSHA standard 29 CFR Part 1910.132, requiring a formal hazard assessment

22 out a notice of proposed rule-making for 42 CFR Part 486, specifically the section that covers the o

23 tions: Protection of Human Subjects title 45 CFR 46) and regulations governing the return of individu

24 27 was more potent in MCF-7:CFR cells than six BET inhibitors in clinical trials.

25 h inhibition in fulvestrant-resistant (MCF-7:CFR) cells was confirmed in endocrine-resistant, palboci

26 135 studies with data on incidence (n = 90), CFR (n = 64), or serotype (n = 45).

27 A CFR group (n = 240) was compared with a non-CFR group (n

28 moxifloxacin dose of 25 mg/kg/day achieved a CFR > 90% in infants, but the optimal dose was 20 mg/kg/

29 le, as well as within pairs discordant for a CFR of <2.5.

30 at experienced an outbreak during 2009 had a CFR of 0.2% compared with 4.3% among other districts.

31 Fifty-eight percent had an abnormal CFR (of which 96% also had an abnormal AchFR).

32 Although an abnormal CFR increases the probability of significant obstructive

33 ) presented disturbed hemodynamics: abnormal CFR in 28 (52%) and MCD in 18 (33%).

34 imum flow to baseline flow at rest; abnormal CFR was defined as a ratio < 2.5.

35 toddlers, administered once daily, achieved CFR >/= 90%, with <10% achieving linezolid AUC0-24 assoc

36 -0.141; P < .001), with projected vs actual CFR equating to 359 lives saved.

37 The adjusted CFR estimates (95% CI) for the 2013-2016 West African ep

38 The adjusted CFR estimates for the 2013-2016 West African epidemic we

39 The adjusted CFR estimates improved the naive CFR estimates obtained

40 ore prevalent (64.8% vs 43.4%; P < .001) and CFR was lower (1.9 +/- 1.1 vs 2.2 +/- 0.7; P < .001) in

41 Maximal MBF <1.8 mL.g(-1).min(-1) and CFR<2 were considered impaired.

42 ith an IMR>40, the combination of IMR>40 and CFR</=2.0 did not have incremental prognostic value.

43 egorized according to IMR (</=40 or >40) and CFR (</=2.0 or >2.0).

44 , P=0.055), and in vessels with FFR>0.80 and CFR<2 (n=28, 39%), IMR had a wide dispersion (7-72.7 U),

45 e (CFR) agreement groups, using FFR>0.80 and CFR<2 as cutoffs.

46 to one for the estimation of MBF (0.986) and CFR (0.960) in repeated (82)Rb studies.

47 lic of Congo, including age distribution and CFR.

48 eGFR and CFR were associated with diastolic and systolic indices,

49 lower left ventricular ejection fraction and CFR.

50 ation between cardiac autonomic function and CFR.

51 ent elevation, angiographic blush grade, and CFR, IMR has superior clinical value for risk stratifica

52 The median IMR and CFR were 25 (interquartile range, 15-48) and 1.6 (interq

53 IMR and CFR were measured in the culprit artery at the end of pe

54 ith the use of the CAD prognostic index, and CFR was measured noninvasively by positron emission tomo

55 mated by using the CAD prognostic index, and CFR was quantified by using positron emission tomography

56 Change in MBF and CFR at 1 y were not different across groups of patients

57 dent and integrated value of maximal MBF and CFR for predicting cardiovascular death.

58 MBF and CFR were quantified in 4029 consecutive patients (median

59 Association of maximal MBF and CFR with cardiovascular death was assessed using Cox and

60 on in same subject, (3) stress perfusion and CFR after adenosine compared with dipyridamole, (4) hete

61 e protocol with maximum stress perfusion and CFR, (2) test-retest precision in same subject, (3) stre

62 flow capacity combining stress perfusion and CFR, and (5) potential relevance for patients with risk

63 When stratified by sex and CFR, only women with severely impaired CFR demonstrated

64 s the association between dietary sodium and CFR.

65 d significant after controlling for baseline CFR, change in BMI, race, and statin use.

66 This study provides baseline CFRs by viremia group, which allow appropriate adjustmen

67 is makes it difficult to define the baseline CFRs needed to evaluate treatments in the absence of ran

68 At baseline, CFR decreased (2.15 +/- 0.72, 2.02 +/- 0.65, and 1.88 +/

69 a significant interaction (P=0.039) between CFR and early revascularization by coronary artery bypas

70 sought to determine the association between CFR, angiographic CAD, and cardiovascular outcomes.

71 we observed significant associations between CFR and major adverse outcomes (death, nonfatal myocardi

72 modest inverse correlation was seen between CFR and CAD prognostic index (r=-0.26; P<0.0001).

73 gnificant interaction (P<0.007) seen between CFR and troponin.

74 In multivariable analysis, a binary CFR of less than or equal to 1.93 provided incremental d

75 es deaths increased from 3 among 2224 cases (CFR: 0.13%) in wave 1 to 113 among 4884 cases (CFR: 2.31

76 R: 0.13%) in wave 1 to 113 among 4884 cases (CFR: 2.31%) in wave 2 (P < .001).

77 CFR = 11.7%) and Turkana South (1493 cases; CFR = 1.0%), were surveyed.

78 holds in 2 districts, East Pokot (224 cases; CFR = 11.7%) and Turkana South (1493 cases; CFR = 1.0%),

79 th rubidium-82 injection at 3 minutes caused CFR that was significantly 15.7% higher than the 4-minut

80 uantification of coronary flow reserve (CFR; CFR=stress divided by rest myocardial blood flow) by pos

81 , resulting in 26 901 cases and 1362 deaths (CFR, 5.1%).

82 In Dollo-Ado, 407 cases and 23 deaths (CFR, 5.7%) were reported.

83 In Dadaab, 1370 measles cases and 32 deaths (CFR, 2.3%) were reported.

84 spected cholera cases, including 636 deaths (CFR, 3.7%), were reported all over the country.

85 ring 2007-2009 (16 616 cases and 454 deaths; CFR, 2.7%), which declined rapidly to 0 cases.

86 District CFRs ranged from 0% to 14.3%.

87 Heat stroke had an ED CFR of 99.4/10,000 (95% CI: 78.7, 120.1) visits and was

88 Heat stroke had a high ED CFR.

89 estimated glomerular filtration rate (eGFR), CFR, diastolic and systolic indices, and adverse cardiov

90 atients may be used to evaluate baseline EVD CFRs.

91 Integration of FFR, CFR, and IMR supports the existence of differentiated pa

92 as vasodilator/resting coronary blood flow (CFR and AchFR, respectively).

93 bei, the baseline estimates were as follows: CFR 2.4% (95% credible interval [CrI] 2.1%-2.8%), sCFR 3

94 After also adjusting for CFR, the effect of sex on outcomes was no longer signifi

95 decrease in maximal MBF after adjustment for CFR and clinical covariates).

96 symptomatic patients with normal MPI, global CFR but not CAC provides significant incremental risk st

97 High CFRs in Kenya are related to healthcare access dispariti

98 Premature infants did not have a higher CFR than term infants (P = .62).

99 th lower CFR than their brothers with higher CFR (p < 0.05).

100 al pneumonia deaths by combining in-hospital CFRs with hospital admission estimates from hospital-bas

101 -operator characteristic analysis identified CFR <2.32 as the best discriminating threshold for adver

102 Impaired CFR (below the median) was associated with an adjusted 3

103 Impaired CFR and positive troponin identified patients at highest

104 Impaired CFR was similarly present among women and men, but in pa

105 Impaired CFR, here reflecting microvascular dysfunction, modified

106 Impaired CFR, particularly absent severely obstructive CAD, may r

107 In adjusted analysis, impaired CFR remained independently associated with positive trop

108 rval, 1.37-3.47; P=0.001), and both impaired CFR and positive troponin were independently associated

109 egories was independently driven by impaired CFR irrespective of impairment in maximal MBF.

110 In patients without overt CAD, impaired CFR was independently associated with minimally elevated

111 with metabolic syndrome demonstrate impaired CFR, which is related to the augmentation in resting cor

112 CE was increased in the presence of impaired CFR even among patients with CAC = 0 (1.4% vs. 5.2%, p =

113 x and CFR, only women with severely impaired CFR demonstrated significantly increased adjusted risk o

114 Patients with impaired CFR but preserved maximal MBF had an intermediate cardio

115 tic patients without known CAD with impaired CFR experienced a rate of cardiac death comparable to th

116 ic patients without CAD, those with impaired CFR have event rates comparable to those of patients wit

117 n was independently associated with impaired CFR, representing a hidden biological risk, and a phenot

118 wed that mineralocorticoid blockade improved CFR in men and women with type 2 diabetes, implicating a

119 alocorticoid receptor (MR) blockade improves CFR in individuals with T2DM.

120 In a subset of 144 patients, IMR, CFR, and RRR were measured post-primary percutaneous cor

121 Decline in CFR after the mandate was associated with an increasing

122 CI], 1.38-2.31; P<0.001 per unit decrease in CFR after adjustment for maximal MBF and clinical covari

123 th events (hazard ratio for unit decrease in CFR, 2.02; 95% confidence interval, 1.20-3.40; P=0.008;

124 rs was associated with a 10.3% difference in CFR after adjustment for potential confounders (P = 0.02

125 Differences in CFR were no longer present after correcting rest flows f

126 to 14.4 +/- 6.3; p = 0.001) and increase in CFR (3.8 +/- 1.7 to 4.8 +/- 1.5; p = 0.017), from baseli

127 To confirm the increase in CFR and identify risk factors for measles death, we enha

128 The increase in CFR with spironolactone remained significant after contr

129 of death that partly explained variations in CFR in the study population.

130 rdial K(ATP) channels and not via increasing CFR.

131 d discordant categories based on integrating CFR and maximal MBF identify unique prognostic phenotype

132 mong women and men, but in patients with low CFR (<1.6, n=163), women showed a higher frequency of no

133 Subjects with low CFR experienced rates of events similar to those of subj

134 high angiographic scores, and those with low CFR or high CAD prognostic index showed the highest risk

135 bypass grafting, such that patients with low CFR who underwent coronary artery bypass grafting, but n

136 Lower CFR was associated with increased risk for major adverse

137 1000 mg/d was associated with a 10.0% lower CFR (95% CI: -17.0%, -2.5%) after adjustment for demogra

138 top quintile (>1456 mg/d) having a 20% lower CFR than the bottom quintile (<732 mg /d).

139 Patients with MVO had lower CFR at PPCI and day 1 (p < 0.05) and a trend toward high

140 ound that women had a higher rest MBF, lower CFR, and worse diastolic function compared with men.

141 cept VCAM-1, were higher in twins with lower CFR than their brothers with higher CFR (p < 0.05).

142 sodium consumption is associated with lower CFR.

143 all, children aged </=5 years had the lowest CFR and were brought to hospitals more quickly and treat

144 cular ejection fraction of 62%, and a median CFR of 1.8.

145 es, with a resulting age-standardized median CFR of 1.9%.

146 In multivariable models, CFR, but not eGFR, was independently associated with car

147 At 6 months, CFR and IMR were not significantly different between the

148 Moreover, CFR detects DIH 17.5 h earlier than histological changes

149 he adjusted CFR estimates improved the naive CFR estimates obtained without imputation and were more

150 ver, the accuracy and precision of the naive CFR remain limited because 44% of survival outcomes were

151 explained 93.6% of the variance in the naive CFR.

152 explained 93.6% of the variance in the naive CFR.

153 CFR group (n = 240) was compared with a non-CFR group (n = 215).

154 ntly higher in the CFR group than in the non-CFR group for iron [i.e., 0.6 mg/100 kcal (0.4-0.8 mg/10

155 A normal CFR has a high negative predictive value for excluding h

156 A normal CFR value should prompt the measurement of AchFR.

157 Of those with a normal CFR, 53% had an abnormal AchFR, and 47% had a normal Ach

158 Vessels with FFR</=0.80 and normal CFR presented the lowest IMR, suggesting a preserved mic

159 om which only 20 (37%) presented both normal CFR and IMR.

160 ith CFR </=2.5, parathyroidectomy normalized CFR (3.3+/-0.7 versus 2.1+/-0.5; P<0.0001).

161 -elevationl infarction, IMR and RRR, but not CFR, were associated with MVO, myocardial hemorrhage, in

162 The overall observed CFR varies widely, with the highest rates in Italy (9.3%

163 Addition of CFR to clinical and imaging risk models improved risk di

164 crosstalk-free duplex imaging capability of CFR enables longitudinal measurement of two correlated b

165 ss the six locations in Europe, estimates of CFR varied widely.

166 yses, patients with concordant impairment of CFR and maximal MBF had high cardiovascular mortality of

167 % CI, 0.84-9.26]; P=0.019), independently of CFR<=2.0, RRR<=1.7, myocardial perfusion grade<=1, and T

168 lysis, only PTH increased the probability of CFR </=2.5 (P=0.03).

169 d to infection, giving an upper 95% bound on CFR of 0.6%.

170 characteristic analysis demonstrated optimal CFR and AchFR thresholds for identifying exercise pathop

171 The optimal CFR and AchFR diagnostic thresholds are 2.6 and 1.5, wit

172 When the adoption of optimized CFRs is constrained by economic access for or acceptabil

173 assess effectiveness of promoting optimized CFRs for improving maternal knowledge, feeding practices

174 t or discordant impairment of maximal MBF or CFR.

175 , "fatality", "death", "died", "deaths", or "CFR" for articles published in English.

176 1-3, 4-6, 7-9, and >/= 10 after an outbreak, CFRs were 1.6%, 0.66%, 0.33%, and 0.25%, respectively.

177 Nevertheless, the overall CFR decreased during this period.

178 The overall CFR during 2010-2017 was 2.5/1000: 6.0/1000 for women an

179 8.7%, with Egypt having a very low pediatric CFR.

180 r mass) during stress (n = 136), a preserved CFR (>1.93) excluded high-risk CAD with a high sensitivi

181 y, diabetics without known CAD and preserved CFR had very low annualized cardiac mortality, which was

182 Patients with concordantly preserved CFR and maximal MBF had the lowest cardiovascular mortal

183 Patients with preserved CFR but impaired maximal MBF had low cardiovascular mort

184 with prior CAD, whereas those with preserved CFR have event rates comparable to those of nondiabetics

185 ent rates comparable to those with preserved CFR, independently of revascularization.

186 rubidium-82 activation at 3 minutes produced CFR that averaged 15.7% higher than that in the 2/4-minu

187 The case fatality rate (CFR) for children was 48.7%, with Egypt having a very lo

188 tinuing to grow, but the case fatality rate (CFR) has steadily decreased.

189 The suicide case-fatality rate (CFR)-the proportion of suicidal acts that are fatal-depe

190 NaHS increased coronary flow rate (CFR) during baseline (mean +/- SD for AUC: 134.3 +/- 91.

191 755]; P < .001) and the case fatality rate ([CFR] 13.7 [469 of 3429] vs 7.6 [1344 of 17,660]; P < .00

192 s were reported (overall case-fatality rate [CFR], 3.9%), affecting all regions of the country.

193 There were 31 deaths (case fatality rate [CFR], 6.2% [95% confidence interval, 4.3%-8.6%]).

194 severity" scenario with case fatality rates (CFR) of 0.05%-0.1%, or a "high severity" scenario (CFR:

195 tcomes, and examined ED case fatality rates (CFR).

196 disease 2019 (COVID-19) case-fatality rates (CFRs) across countries, leading to uncertainty about the

197 to explore patterns in case-fatality rates (CFRs) at 30 days and 1 year and to explore whether these

198 Case fatality rates (CFRs) during 2010-2017 were calculated using incidence d

199 icrobials may result in case fatality rates (CFRs) exceeding 70%(4,5).

200 failure with up to 33% case fatality rates (CFRs).

201 se onset and calculated case fatality rates (CFRs).

202 ance data and estimated case fatality rates (CFRs).

203 d acquisition risks and case fatality rates (CFRs).

204 d more insight into the case fatality ratio (CFR) and how it varies with age and other characteristic

205 an ever before into the case fatality ratio (CFR) and how it varies with age and other characteristic

206 lia suggested increased case fatality ratio (CFR) in the second of 2 waves.

207 il, giving an estimated case fatality ratio (CFR) of 0.4% (range: 0.3 to 1.8%) based on confirmed and

208 The case fatality ratio (CFR) of Ebola virus disease (EVD) can vary over time and

209 on rate and in-hospital case-fatality ratio (CFR) of pneumonia in older adults, stratified by age and

210 The case-fatality ratio (CFR) was 17.4% (95% confidence interval [CI], 13.1%-21.6

211 The case-fatality ratio (CFR) was 43%.

212 The case-fatality ratio (CFR), calculated from total numbers of reported cases an

213 uspected cholera cases (case fatality ratio [CFR], 0.87%).

214 untry, with 657 deaths (case-fatality ratio [CFR], 6.1%).

215 haracteristics such as incidence, sex ratio, CFR, and seasonality differ substantially across the aff

216 ttack rates (ARs), and case fatality ratios (CFRs) for each camp.

217 We described case fatality ratios (CFRs), pathogen distribution, and annual changes in sero

218 Complementary feeding recommendations (CFRs) with the use of locally available foods can be dev

219 he washout rate) was associated with reduced CFR.

220 In the Cape Floristic Region (CFR) of South Africa, a fire-prone biodiversity hotspot,

221 ty in the megadiverse Cape Floristic Region (CFR).

222 ministration 21 code of federal regulations [CFR] 50.24).

223 Consequently, the reported CFRs are larger than they would have been had the data i

224 molecular chemo-fluoro-luminescent reporter (CFR) is synthesized for duplex imaging of drug-induced h

225 in combination with a coronary flow reserve (CFR</=2.0), in the culprit artery after emergency percut

226 ndrome showed a lower coronary flow reserve (CFR) (2.5 +/- 1.0) than those without metabolic syndrome

227 outcomes and baseline coronary flow reserve (CFR) after intracoronary adenosine in 189 women referred

228 assified in 4 FFR and coronary flow reserve (CFR) agreement groups, using FFR>0.80 and CFR<2 as cutof

229 low reserve (FFR) and coronary flow reserve (CFR) and the index of microcirculatory resistance (IMR);

230 We assessed coronary flow reserve (CFR) as a marker of coronary microvascular function in a

231 oss-sectional design, coronary flow reserve (CFR) assessed by cardiac (82)Rb-positron emission tomogr

232 cardial perfusion and coronary flow reserve (CFR) by positron emission tomography, where submaximal s

233 resistance (IMR), and coronary flow reserve (CFR) for predicting microvascular obstruction (MVO), myo

234 ular dysfunction as a coronary flow reserve (CFR) of less than 2.0.

235 Coronary flow reserve (CFR) was determined from positron emission tomography.

236 blood flow (MBF) and coronary flow reserve (CFR) with dynamic (82)Rb PET is feasible.

237 othesis that a normal coronary flow reserve (CFR) would be helpful for excluding the presence of high

238 Reduced coronary flow reserve (CFR), an indicator of coronary microvascular dysfunction

239 levation and impaired coronary flow reserve (CFR), an integrated measure of coronary vasomotor functi

240 Coronary flow reserve (CFR), an integrated measure of focal, diffuse, and small

241 Coronary flow reserve (CFR), an integrated measure of large- and small-vessel C

242 mine the evolution of coronary flow reserve (CFR), index of microcirculatory resistance (IMR), ratio

243 blood flow (MBF) and coronary flow reserve (CFR), termed coronary flow capacity, allows for comprehe

244 Impaired coronary flow reserve (CFR), the ratio of adenosine-stimulated to rest myocardi

245 al dietary sodium and coronary flow reserve (CFR), which is a measure of overall coronary vasodilator

246 titative estimates of coronary flow reserve (CFR), with respect to prediction of clinical outcomes.

247 hyperemic MBF versus coronary flow reserve (CFR).

248 ET) and assessment of coronary flow reserve (CFR).

249 ent quantification of coronary flow reserve (CFR; CFR=stress divided by rest myocardial blood flow) b

250 r calcium on the calcium-frequency response (CFR) in our model and three altered models.

251 ed, and the cumulative fraction of response (CFR) was calculated.

252 aria using comparative functional responses (CFRs) and cohabitation trials.

253 lobal ischemia, and early revascularization, CFR and CAD prognostic index were independently associat

254 a-analyses of incidence, case fatality risk (CFR), and serotype prevalence.

255 teristics of the pandemic (acquisition risk, CFR) and length of delay (length of pandemic, waitlist p

256 f 0.05%-0.1%, or a "high severity" scenario (CFR: 0.25%-0.5%).

257 ographies at low-risk physiological severity CFR >/=2.3 to CFR <2.0, thereby implying high-risk quant

258 We sought to investigate the impact of sex, CFR, and angiographic CAD severity on adverse cardiovasc

259 h given a particular method (method-specific CFR).

260 Method-specific CFRs were higher for males and older persons.

261 uicide attempts, overall and method-specific CFRs, and distribution of methods used, by sex, age grou

262 Variation in overall suicide CFR between sexes and across age groups, regions, and ur

263 Hyperemic MBF was more accurate than CFR, implying that a single measurement of MBF in diagno

264 hyperemic MBF was significantly higher than CFR (80% vs. 68%, respectively, P = 0.02), with optimal

265 proportional hazards analysis revealed that CFR improved model fit, risk discrimination, and risk re

266 The CFR for IMD-W was 16% (32/199, P < .001).

267 The CFR intervention improved mothers' knowledge and childre

268 The CFR is not a good predictor of overall mortality from SA

269 The CFR significantly improved prediction of adverse outcome

270 The CFR was high.

271 onset, mean viremia remained stable, and the CFR increased with viremia, V, from 21% (95% CI 16%-27%)

272 ected for model imperfection to estimate the CFR without imputation, with imputation and adjusted wit

273 ected for model imperfection to estimate the CFR without imputation, with imputation, and adjusted wi

274 ortality adjusted for biases and examine the CFR, the symptomatic case-fatality ratio (sCFR), and the

275 asures of ecological opportunity explain the CFR's longitudinal diversity gradient.

276 s for calcium, iron, niacin, and zinc in the CFR group (23, 0.6, 0.7, and 0.5 mg/100 kcal, respective

277 t densities were significantly higher in the CFR group than in the non-CFR group for iron [i.e., 0.6

278 before coincided with a 14% increase in the CFR.

279 sed viremia and other variables to model the CFR.

280 Compared to adults (15-44 y old [y.o.]), the CFR was larger in young children (0-4 y.o.) (odds ratio

281 )= 0.935), as was the reproducibility of the CFR estimates (R(2) = 0.841).

282 n the sensitivity and the specificity of the CFR for identifying high-risk CAD varied substantially d

283 t clinical and demographic predictors of the CFR.

284 lar phylogenies for 21 clades endemic to the CFR.

285 The CFRs significantly increased intakes of calcium, iron, n

286 The CFRs were similar between patients who received ribaviri

287 The CFRs, which were developed using LP, were promoted in an

288 ow-risk physiological severity CFR >/=2.3 to CFR <2.0, thereby implying high-risk quantitative severi

289 rdiovascular events were partly mediated via CFR.

290 ject decreasing precipitation in the western CFR, which would slow recovery rates there, likely reduc

291 showing evidence of harm in scenarios where CFRs were substantially higher for KT recipients (eg, >=

292 dietary sodium was inversely associated with CFR (P-trend = 0.03), with the top quintile (>1456 mg/d)

293 t rate were the only factors associated with CFR (P=0.04, P=0.01, and P=0.006, respectively).

294 dietary sodium is inversely associated with CFR independent of CVD risk factors and shared familial

295 lerotic burden was inversely correlated with CFR (r=-0.207, P=0.055), and in vessels with FFR>0.80 an

296 ic activity, were positively correlated with CFR after adjustment for age and heart rate.

297 - mediastinum ratio remained correlated with CFR after further adjustment.

298 In all PHPT patients with CFR </=2.5, parathyroidectomy normalized CFR (3.3+/-0.7

299 In patients with CFR </=2.5, PTH was higher (26.4 pmol/L [quartiles 1 and

300 ted MACE rates were higher for patients with CFR <2.0 compared with >/=2.0 (1.9 vs. 5.5%/year, p = 0.