ライフサイエンスコーパス: CGA

1 CGA 325'615 in nanomolar concentrations or DCB in microm

2 CGA acts as an antioxidant in plants and protects agains

3 CGA bound deeply into the MP structure hydrophobic cavit

4 CGA can be conducted in an outpatient cancer community u

5 CGA content varied greatly (27.33-121.25mg/200 ml coffee

6 CGA drastically increased the release activity of the In

7 CGA has been shown to exist primarily in a tetrameric st

8 CGA is shown not a major contributor to CO2 formation, a

9 CGA isolates were obtained from diverse locations across

10 CGA isomer content was positively correlated (p<0.001) t

11 CGA, CFA and QNA primarily confer the bitterness, astrin

12 re randomly assigned (standard arm, n = 251; CGA arm, n = 243).

13 3-CGA and caffeine were found at higher concentrations in

14 3-CGA concentrations and pH were comparable between cold a

15 ations of caffeine and 3-chlorogenic acid (3-CGA) in cold brew coffee were investigated by brewing fo

16 It was determined that caffeine and 3-CGA concentrations reached equilibrium according to firs

17 The grind size did not impact 3-CGA and caffeine concentrations of cold brew samples sig

18 y of cold brew coffee is likely not due to 3-CGA or caffeine concentrations considering that most aci

19 G of 5' TCG 3' and by extruding the C of 5' CGA 3'.

20 guanine bases, primarily in the sequence 5'-CGA where the damaged nucleobase is flanked by two high-

21 is motif, called loop 6, has the sequence 5'-CGA-3'...5'-GAC-3' flanked on both sides by cis Watson-C

22 n was found in the other context studied, 5'-CGA-3'.

23 missense mutation was detected in codon 82 (CGA to GGA) that would create a non-conservative substit

24 A CGA includes an evaluation of an older individual's func

25 At discharge, a CGA score (range, 0-10) was calculated based on limitati

26 olymerase showed a striking preference for a CGA sequence at positions -12 to -10 rather than the lon

27 emonstrates that the variables examined in a CGA can predict morbidity and mortality in older patient

28 ng data show the benefits of incorporating a CGA in the evaluation of older patients with cancer.

29 Transfection of bovine CGA into a CGA-deficient PC12 clone rescued the regulated secretory

30 Stable transfection of CGA into a CGA-deficient pituitary cell line, 6T3, lacking a regula

31 ome geriatric syndromes may be modifiable, a CGA could enhance risk stratification, reduce age-relate

32 of the first studies evaluating the use of a CGA in developing interventions to improve the care of o

33 le discusses recent advances on the use of a CGA in older patients with cancer.

34 However, heating of a CGA moiety, caffeic acid, resulted in high yield of CO2

35 ospective trials evaluating the utility of a CGA to guide interventions to improve the quality of can

36 Sequencing showed a CGA-->TGA nonsense mutation at codon 306 in exon 8.

37 ence from recent studies demonstrates that a CGA can predict morbidity and mortality in older patient

38 les of neuroendocrine cells, chromogranin A (CGA) and chromogranin B (CGB), have been shown to underg

39 the Ca(2+) storage protein, chromogranin A (CGA), couples with InsP(3)-gated Ca(2+) channels (InsP(3

40 ocrine cells is dependent on chromogranin A (CGA).

41 -associated Escherichia coli clonal group A (CGA), a widespread cause of drug-resistant urinary tract

42 lonephritis isolates were in clonal group A (CGA; responsible for 38-51% of co-trimoxazole resistance

43 E. coli "clonal group A" (CGA) and the O2:K5/K7:H1 and O75:K+ clonal groups were s

44 oxidants, and among these, chlorogenic acid (CGA) accumulates to high levels in some crop plants.

45 pecific transformations of chlorogenic acid (CGA) and sesquiterpene lactones (STL) during SGID enhanc

46 oligosaccharides (FOS) and chlorogenic acid (CGA) contents were also evaluated.

47 wo CO2 formation pathways (chlorogenic acid (CGA) degradation and Maillard reaction) during coffee ro

48 5) affected the content of chlorogenic acid (CGA) isomers, several indices of browning and subsequent

49 tammetric determination of chlorogenic acid (CGA) measured as 5-O-caffeoylquinic acid (5-CQA).

50 ine (TBA) derivatives when chlorogenic acid (CGA) quinones and amino acids react can be unappealing f

51 as prepared by reaction of chlorogenic acid (CGA) with tryptophan (TRP) in air at pH 9 (37% w/w yield

52 Alkaline reactions of chlorogenic acid (CGA) yield undesirable development of brown or green pig

53 Chlorogenic acid (CGA), caffeic acid (CA), and quinic acid (QA) were quant

54 on of an activator of CaN, chlorogenic acid (CGA), on behavioral and electrophysiological indices of

55 Phenolic acids, mainly chlorogenic acid (CGA), represent the major compounds, followed by anthocy

56 Chlorogenic acid (CGA, caffeoyl quinate) is the major soluble phenolic com

57 caffeoylquinic acids (e.g. chlorogenic acid [CGA]) and the dicaffeoylquinic acids (diCQAs) have been

58 Chlorogenic acids (CGA) are a class of polyphenols noted for their health b

59 fect may be attributed to chlorogenic acids (CGA), which were the most abundant PA in digested coffee

60 In addition, CGA 325'615, but not DCB, also causes accumulation of Ce

61 cer patients to complete a self-administered CGA and then to characterize cancer patients across mult

62 e new reassignments of arginine codons (AGG, CGA, and CGG), representing the first sense codon change

63 The charophyte green algae (CGA, Streptophyta, Viridiplantae) occupy a key phylogene

64 otential anti-greening approach for alkaline CGA quinone-amine greening.

65 ments, limiting the utilization of alkalized CGA-rich foods.

66 s induction of chorionic gonadotropin alpha (CGA) and chorionic gonadotropin beta (CGB) genes, which

67 sduction, we used comparative gene analysis (CGA) combined with pathway visualization software to ide

68 matrix (i.e., comparative genomic analysis [CGA]) identified a candidate core genome consisting of 1

69 olar range in milk samples with added CA and CGA, confirming covalent bonding between milk proteins a

70 oteins lay between those of purified CGB and CGA, CGB aggregation showing the highest degree of aggre

71 he wobble position which reads CGU, CGC, and CGA bypasses much more frequently from the last codon th

72 Three of six arginine codons (CGU, CGC, and CGA) are decoded by two Escherichia coli tRNA(Arg) isoac

73 isotope analogs, CA-[(13)C(3),(15)N]Cys and CGA-[(13)C(3),(15)N]Cys.

74 Protein-bound CA-Cys and CGA-Cys were detected in the micro-molar range in milk s

75 ity of individual anthocyanins in the EE and CGA samples.

76 esults indicate that the contents of FOS and CGA were maintained in the pulping, enzymatic maceration

77 ult, in addition to higher levels of FOS and CGA, some mineral elements, such as K, Ca and P, and ess

78 compound in switchgrass, and the lignin and CGA biosynthetic pathways potentially share intermediate

79 In the standard and CGA arms, 35.1% and 45.7% of patients received a carbopl

80 In the standard and CGA arms, median TFFS times were 3.2 and 3.1 months, res

81 hout sorbic acid) and colloidal gas aphrons (CGA) separation; a surfactant (TWEEN20) based separation

82 The arginine (Arg, CGA) to stop (UGA) mutation is the most common PTC.

83 bromatosis 1 (NF1) mRNA changes an arginine (CGA) to a UGA translational stop codon, predicted to res

84 The pause sites map to a rare arginine (CGA) codon and to an adjacent threonine (ACA) codon.

85 The proportions of coal gangue ash (CGA) replacement with silica fume (SF: 0-20%) were varie

86 Comprehensive geriatric assessment (CGA) can contribute valuable information to oncologists

87 Comprehensive geriatric assessment (CGA) has aided the medical community greatly in understa

88 Comprehensive geriatric assessment (CGA) has been associated with improved outcomes in older

89 lts of a comprehensive geriatric assessment (CGA) in 150 patients with age >=70 years and serum sodiu

90 ceived a comprehensive geriatric assessment (CGA) in our Senior Adult Oncology Program (SAOP).

91 are with comprehensive geriatric assessment (CGA) in the home is one approach to deal with the increa

92 ore on a comprehensive geriatric assessment (CGA) is associated with worse prognosis during hospitali

93 use of a comprehensive geriatric assessment (CGA) is one example of this effort.

94 Comprehensive geriatric assessment (CGA) is recommended to assess the vulnerability of elder

95 nderwent comprehensive geriatric assessment (CGA).

96 plate strand 5'-d(AAC GC-(1) T(-)(2) ACC ATC CGA ATT CGC CC), I (dG = (+)-trans- and (-)-trans-anti-B

97 od of developing central geographic atrophy (CGA) and neovascular (NV) AMD.

98 Chromogranins A and B (CGA and CGB) are high capacity, low affinity calcium (Ca

99 Chromogranins A and B (CGA and CGB), the major proteins of the secretory vesicl

100 Both CGA and CGB associate with inositol 1,4,5-trisphosphate

101 of 5.5, as found in secretory vesicles, both CGA and CGB bind to the InsP3R.

102 Transfection of bovine CGA into a CGA-deficient PC12 clone rescued the regulate

103 s modulation of InsP(3)R channel activity by CGA appears to be an essential component in the control

104 mulation of non-crystalline glucan caused by CGA 325'615 mimics the phenotype of the cellulose-defici

105 in the cell, the heterotetramer formation by CGA and CGB not only raises the possibility of interacti

106 Genes identified by CGA were cross-referenced with the published signature-t

107 ovalent bonding between milk proteins and CA/CGA.

108 precisely converting four codons (CAA, CAG, CGA, and TGG) into STOP codons without DSB formation.

109 control vector contained the codon pair CCC CGA in the zero reading frame, raising the possibility t

110 e strong support for the hypothesis that CCC CGA in the zero frame is indeed a weak translational fra

111 ur DNA oligomers, d(*CG*CGT*CG*CG) and d(*CG*CGA*CG*CG) (*C = C or br5C), have been synthesized and a

112 ted for the br5C-d(*CG*CGT*CG*CG)+br5C-d(*CG*CGA*CG*CG) duplex which incorporates a Z-Z junction.

113 ing the br5C-d(*CG*CGT*CG*CG) and br5C-d(*CG*CGA*CG*CG) nonamers together converts a fraction of the

114 nd treatment allocation on the basis of CGA (CGA arm: carboplatin-based doublet for fit patients, doc

115 mate-based selective MMP-12 inhibitors (CGA, CGA-1, and AGA) and the methodology to obtain MMP-12 sel

116 1 mutations (11/16), all A:T to G:C changes (CGA).

117 mRNA modifies cytidine in an arginine codon (CGA) at nucleotide 2914 to a uridine (UGA), creating an

118 resulting in a premature termination codon (CGA-TGA) on both alleles.

119 D) encapsulation of key compounds in coffee (CGA 1, CFA 2, and QNA 3), a systematic, comprehensive st

120 eine (CA-Cys) and chlorogenic acid-cysteine (CGA-Cys) adducts and their stable isotope analogs, CA-[(

121 anti-greening strategy, given that cysteine-CGA conjugates are colorless.

122 enol regeneration and formation of cysteinyl-CGA conjugates, which also contributed to antioxidant ca

123 altered triplets within long stretches of d(CGA) triplets.

124 tivity of oligonucleotides composed of the d(CGA) motif and several structurally related sequence var

125 tered by changing the 5'-nucleobase of the d(CGA) triplet and the frequency and position of the alter

126 into the stability and versatility of the d(CGA) triplet repeat motif and provides constraints for u

127 The d(CGA) triplet repeat motif is structurally dynamic and ca

128 Unlike DCB, CGA 325'615 also causes concomitant accumulation of non-

129 L(Arg1,2)(ICG) with I(34) was able to decode CGA.

130 2 additional models were developed to detect CGA in different scenarios.

131 The deep learning models (GA detection, CGA detection from all eyes, and centrality detection fr

132 30% less likely than their peers to develop CGA and NV AMD.

133 Tomatoes with elevated CGA levels could be used in foods with specific benefits

134 intraluminal pH is 7.5, as found in the ER, CGA totally dissociates from InsP3R, whereas CGB only pa

135 echanistic analyses at the endogenous ERVW1, CGA, and CGB loci revealed a regulatory axis in which LS

136 Observations of extant CGA species suggest the existence of some of the evoluti

137 uced dense-core granules, immunoreactive for CGA, in nonendocrine fibroblast CV-1 cells.

138 sisted for development of NV AMD but not for CGA.

139 innamoyltransferase (HQT) is responsible for CGA biosynthesis in tobacco, tomato and globe artichoke,

140 elected elderly cancer patients benefit from CGA and geriatric interventions.

141 selection of elderly who would benefit from CGA using screening tools such as the Vulnerable Elders-

142 he rate limiting step for CO2 formation from CGA.

143 to predict a consensus binding site of GTCG/CGA/G for the FruA DNA-binding domain.

144 We also provide evidence that the herbicide CGA 325'615 (Syngenta, Basel), which inhibits synthesis

145 n experimental thiatriazine-based herbicide, CGA 325'615.

146 The highest CGA yield (76.1 +/- 5.2 mg/g SCG(initial)) occurred betw

147 fessional team assessment approach, however, CGA may be time consuming and costly.

148 The results of SF (> 10%) in CGA-based geopolymer stabilizer soil attained the lowest

149 Anthocyanins in CGA samples showed higher stability (half-life = 55 d) t

150 yl acceptor, and could therefore function in CGA biosynthesis.

151 nes encoding enzymes potentially involved in CGA biosynthesis in switchgrass.

152 transferases (HCT/HQT) have been involved in CGA production, of which HCT reflects CGA levels.

153 differences in alpha-glucosidase inhibition, CGA showed a decreasing trend upon digestion.

154 ced differences in a-glucosidase inhibition, CGA showed a decreasing trend upon digestion.

155 droxamate-based selective MMP-12 inhibitors (CGA, CGA-1, and AGA) and the methodology to obtain MMP-1

156 IS-CGA-LLME is a three-step extraction process that include

157 t-assisted liquid-liquid microextraction (IS-CGA-LLME) as fast mycotoxin extraction (FaMEx) technique

158 ovascular effect of coffee may relate to its CGA content.

159 Key CGA domains included disability, malnutrition, depressio

160 le matrix proteins and the vesicle membrane, CGA and CGB are proposed to play essential roles in the

161 Buffered 2.55 mM CGA: 5.09 mM lysine: (0-5.09) mM cysteine solutions at p

162 ntre stage, diuretics and disease modifiers, CGA domains of disability, malnutrition, Short Physical

163 Moreover, CGA and CGB, as well as several other secretory vesicle

164 he myofibrillar protein-chlorogenic acid (MP-CGA) complexes binding in different environments (pH 6.0

165 ficant differences, with the non-covalent MP-CGA complexes formed at pH 6.0 showing significantly hig

166 required both AnAflR and at least one TCG(N5)CGA AflR binding site.

167 amining the contribution of the three TCG(N5)CGA elements in the 1.1 kb promoter region of stcU using

168 binds to the palindromic sequence 5'-TCG(N5)CGA-3' found in the promoter regions of several aflatoxi

169 The new CGA-specific PCR assay, which exhibited interlaboratory

170 urthermore, the difference in the ability of CGA and CGB to regulate the InsP3R/Ca2+ channel and the

171 r experiments in the presence and absence of CGA.

172 o be the principal route for accumulation of CGA in solanaceous species.

173 lecular docking predicted a high affinity of CGA for a-glucosidase.

174 lecular docking predicted a high affinity of CGA for alpha-glucosidase.

175 Assessment of CGA domains improved National Amyloidosis Centre prognos

176 rs) and treatment allocation on the basis of CGA (CGA arm: carboplatin-based doublet for fit patients

177 NSCLC, treatment allocation on the basis of CGA failed to improve the TFFS or OS but slightly reduce

178 ith an experimental strategy on the basis of CGA.

179 her concentrations and different behavior of CGA metabolites depending on the conjugated chemical pos

180 provement in the strength characteristics of CGA-SF in geopolymer-stabilized low-plasticity clay.

181 High concentrations of CGA and relatively low pH occur in the vacuoles of plant

182 coffee had a significantly higher content of CGA.

183 ty and 100% specificity for the detection of CGA among 138 diverse clinical and reference E. coli iso

184 ld allow the rapid and specific detection of CGA by any laboratory equipped for diagnostic PCR.

185 rol analysis based upon the determination of CGA content in specialty and traditional coffee beverage

186 Downregulation of CGA expression in a neuroendocrine cell line, PC12, by a

187 In addition to the effects of CGA 325'615 on levels of both of these proteins, the lev

188 may also be applied to the identification of CGA.

189 The 12-y incidence of CGA and NV AMD in participants at moderate-to-high risk

190 Incubation of CGA with crude extracts of tomato fruits led to the form

191 ated, followed immediately by LA infusion of CGA.

192 We found that intra-LA infusions of CGA following cue extinction or reconsolidation reduced

193 ncentration-dependent cysteine inhibition of CGA-lysine greening was attributed to redox diphenol reg

194 ependence of the pH-dependent interaction of CGA and CGB by analytical ultracentrifugation and found

195 mRNA levels of CGA, CGB, PPARG, CYP19A1, CYP11A1, PTGS2, EREG, and the

196 caused plants to accumulate higher levels of CGA, with no side-effects on the levels of other soluble

197 gh-anthocyanin varieties have high levels of CGA.

198 However, one molecule of CGA bound to one molecule of CGB at pH 7.5 with DeltaG0

199 ntrifugation and found that two molecules of CGA bound to two molecules of CGB at pH 5.5 with DeltaG0

200 Overexpression of CGA induced dense-core granules, immunoreactive for CGA,

201 These results highlight the broad range of CGA quantity in commercial coffee and demonstrate that c

202 The reassignments of CGA and/or CGG were found in genomes with low GC content

203 shown to be a member or a close relative of CGA (by ERIC2 PCR and RAPD analysis, respectively) and y

204 in the remaining four probands, targeting of CGA-->TGA mutations in genomic DNA revealed a premature

205 Stable transfection of CGA into a CGA-deficient pituitary cell line, 6T3, lacki

206 e InsP3R/Ca2+ channel and the variability of CGA/CGB ratios could influence the pattern of InsP3-medi

207 ount of roasting had a detrimental effect on CGA content).

208 ee choice is important in delivering optimum CGA intake to consumers.

209 In the presence of luminal CGB monomers or CGA/CGB heteromers the InsP3R/Ca2+ channel open probabil

210 ction between the InsP3R and CGB monomers or CGA/CGB heteromers, purified mouse InsP3R type I were fu

211 yl quinate to generate caffeoyl shikimate or CGA.

212 A second model was trained to predict CGA presence from the same population.

213 A third model was trained to predict CGA presence from the subset of eyes with GA.

214 active geriatric assessment = 134; proactive CGA = 326): median age was 81 years (IQR 74-88); 326 (55

215 reactive geriatric assessment, and proactive CGA.

216 Using purified CGA and CGB, it recently has been shown that CGA interac

217 hasing might also be exacerbated by the rare CGA Arg codon in the second position due to increased va

218 negate wobble codon recognition of the rare CGA codon by an unknown mechanism, while still allowing

219 clonal groups, including recently recognized CGA.

220 chanisms, including redox coupling to reduce CGA quinones, and thiol conjugation, which forms colorle

221 ved in CGA production, of which HCT reflects CGA levels.

222 lacking m(7)G and m(5)C, and mature tRNA(Ser(CGA)) in mutants lacking Um and ac(4)C.

223 we used a genetic screen to examine tRNA(Ser(CGA)) variants.

224 onstrate that for the wild-type pre-tRNA(Ser)CGA and other pre-tRNAs, Lhp1p is required for the norma

225 that disrupts the anticodon stem of tRNA(Ser)CGA require Lhp1p for growth.

226 though maturation of the mutant pre-tRNA(Ser)CGA requires Lhp1p, introduction of a second mutation th

227 anticodon loop, only tRNA(Ser)AGA, tRNA(Ser)CGA, tRNA(Ser)UGA, and selenocysteine tRNA with UCA (tRN

228 gulation, inositol metabolism, and tRNA(Ser)(CGA) abundance.

229 d show that the mutation lies in a tRNA(Ser)(CGA), which has been modified to translate the nonsense

230 RNAs, and of individually purified tRNA-Ser-CGA.

231 Similarly, CGA infusions following cue re-exposure significantly at

232 The score on a simple CGA is associated with long-term mortality in older pati

233 , and cumulative deficits (sum of the single CGA items).

234 GAA(6N)TGCC (KpnAI), ACA(6N)TYCA (StySEAI), CGA(6N)TACC (StySENI) and TAAC(7N)RTCG (StySGI).

235 pH optimum and a high Km for its substrate, CGA.

236 clones encoding the enzyme that synthesizes CGA, hydroxycinnamoyl-CoA quinate: hydroxycinnamoyl tran

237 a concentration-time profiles of 25 systemic CGA metabolites over 24 h after DGCE consumption and we

238 TAC, GAT.ATC, GTT.AAC, CAC.GTG, AGG.CCT, TCG.CGA, and AAG.CTT), and the adjoining paper describes stu

239 However, long tracts of TCG.CGA showed strong inhibition of DNA synthesis at specifi

240 In view of the interaction of tetrameric CGA with tetrameric inositol 1,4,5-trisphosphate (IP3) r

241 these conjugates proceeds more quickly than CGA dimerization and amine addition reactions mitigating

242 We conclude that CGA is an "on/off" switch that alone is sufficient to dr

243 Our results show that CGA-coupled InsP(3)Rs are more sensitive to activation t

244 The results showed that CGA bound with MP significantly enhanced its antioxidant

245 CGA and CGB, it recently has been shown that CGA interacts with CGB at pH 5.5.

246 in high yield of CO2 (>98%), suggesting that CGA hydrolysis could be the rate limiting step for CO2 f

247 The CGA detection model had values of 0.966 (0.957-0.975), 0

248 ame starting within the next codon after the CGA, our data also support possible contribution to expr

249 The analysis of the association between the CGA score and 2-year subsequent mortality was performed

250 However, the association between the CGA score and long-term mortality is uncertain.

251 ficant reduction (P = 0.93) was seen for the CGA (OR, 1.02; 95% CI, 0.71-1.45).

252 Patients in the CGA arm, compared with standard arm patients, experience

253 sed with the concentration of TWEEN20 in the CGA fraction (6.07-8.58 mM).

254 w-up, 528 of 672 (78.6%) participants in the CGA HAH group versus 247 of 328 (75.3%) participants in

255 The anthocyanins loss in the CGA sample (with the maximum content of surfactant, 8.58

256 A 1-point increase in the CGA score was associated with a 19% higher mortality (ha

257 All components of the CGA score showed a consistent association with higher de

258 Only the CGA content of coffee corresponded to intracellular anti

259 mation of both aromatic and benzylic thiolyl-CGA conjugate species formed with cysteine and glutathio

260 l conjugation, which forms colorless thiolyl-CGA compounds that do not readily participate in color-g

261 rolysis of the quinic acid moiety of thiolyl-CGA conjugates yielded a variety of isomeric species als

262 e also observed a strong preference for this CGA sequence by Escherichia coli sigma(28) RNA polymeras

263 Thus, CGA is broadly disseminated and contributes to co-trimox

264 not only to the vesicle membrane but also to CGA at pH 5.5, with the exception of a few matrix protei

265 However, perceived barriers to CGA include time, familiarity, cost, and lack of a well-

266 atrix proteins that appeared to bind only to CGA or to vesicle membrane.

267 esponding genes, suggest preferred routes to CGA in switchgrass.

268 highest levels, between 25 and 30% of total CGA; subsequent relative quantities were: 4-CQA>3-CQA>5-

269 recognized by tRNA(GGA)(Ser) and UCG by tRNA(CGA)(Ser).

270 Here, we report evidence that tRNASer(CGA) (serU) can, surprisingly, also decode TCA, thereby

271 ation of Penium margaritaceum, a unicellular CGA species.

272 HAH with CGA versus hospital admission with CGA when available using 2:1 randomization.

273 s of coffee positively corresponds best with CGA content.

274 Admission avoidance HAH with CGA led to similar outcomes as hospital admission in the

275 Admission avoidance HAH with CGA versus hospital admission with CGA when available us

276 Purified CGB was also shown to interact with CGA at pH 5.5.

277 on were reproduced experimentally: MnBP with CGA, MBzP with CYP11A1, and MEHP with PTGS2.