ライフサイエンスコーパス: CNP

1 CNP (C-type natriuretic peptide) inhibits myofibrogenesi

2 CNP binds to the structural protein Gag and blocks HIV-1

3 CNP is also widespread in the Plasmodium falciparum geno

4 CNP's outstanding properties in biosensors which go from

5 CNP-cre:TNFR2(fl/fl) mice with TNFR2 ablation in oligode

6 CNP-induced sensitization of TRPV1 activity was attenuat

7 CNP-Sox17 mice showed increased Gli2 protein levels and

8 CNP/dnIRF-1 mice exhibited no phenotypic abnormalities b

9 CNPs are defined by the cognitive function they extract,

10 CNPs can be used as a whole sensor or a part of recognit

11 CNPs of various size are designed by tweaking size (2-25

12 CNPs that exhibit mostly or exclusively PL arising from

13 CNPs upstream of the urate transporter SLC2A9 on chromos

14 o successfully obtain CNP genotypes for 1495 CNPs from 487 human DNA samples of diverse ethnic backgr

15 ion range 8.5x10(-6) to 1.9x10(-9)molL(-1) 2-CNP with a correlation coefficient of (0.999) and a dete

16 ex at 457nm by the 2-chloro-4-nitrophenol (2-CNP) which produced from the reaction of the enzyme with

17 el matrix by various concentrations of the 2-CNP was successfully used as an optical sensor for the a

18 c redox species and anion depletion inside a CNP by diffuse-layer and surface-charge effects in a sol

19 Pyrolysis at 180 degrees C leads to a CNP molecular precursor with a strongly intense photolum

20 pharmacological activity of a 39 amino acid CNP analog (BMN 111) with an extended plasma half-life d

21 While lacking renal actions, CNP is less hypotensive than the cardiac peptides atrial

22 alpha-carboxy nucleoside phosphonate (alpha-CNP), was designed that is recognized by a variety of po

23 particular, the carboxyl oxygen of the alpha-CNP acts as the potential equivalent of the alpha-phosph

24 xygens of the phosphonate group of the alpha-CNP chelate Mg(2+), mimicking the chelation by the beta-

25 alpha-CNPs (i) do not require metabolic activation (phosphoryl

26 alpha-CNPs represent an entirely novel and broad technological

27 the kinetic interaction of the acyclic alpha-CNPs against the herpetic DNA polymerases differs from t

28 In addition, alpha-CNPs were also found to selectively interact with regula

29 kinetic interaction of the cyclopentyl alpha-CNPs against HIV RT.

30 for the synthesis of a series of novel alpha-CNPs, including a Rh(II)-catalyzed O-H insertion that co

31 Alpha-carboxynucleoside phosphonates (alpha-CNPs) are novel viral DNA polymerase inhibitors that do

32 alpha-carboxy nucleoside phosphonates (alpha-CNPs).

33 he cyclopentyl moiety in the prototype alpha-CNPs by a more flexible entity results in a selectivity

34 -1 reverse transcriptase revealed that alpha-CNPs mimic the dNTP binding through a carboxylate oxygen

35 Here we propose a novel method to analyse CNP using spatial statistical modelling.

36 s), NT-proBNP (3 assays), proBNP(1-108), and CNP were measured over 3 visits.

37 he stimulation of NPR-A and NPR-B by ANP and CNP, respectively.

38 IDE rapidly cleaves ANP and CNP, thus inactivating their ability to raise intracellu

39 genes that participate in PTHrP-IHH, BMP and CNP signaling, and many genes that have not previously b

40 nd NPR-B to the stimulation of ANP, BNP, and CNP in cultured cells.

41 Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide recept

42 Phosphorylated p38MAPK was found in CC1- and CNP-expressing differentiated oligodendrocytes of the ad

43 odeling after ischemia or vessel injury, and CNP/NPR-C expression and localization in tissue from pat

44 Both NO and CNP stimulate the synthesis of cGMP and thus the activat

45 primate lentiviruses are CNP-sensitive, and CNP sensitivity/resistance is determined by a single, na

46 mulated genes including IFITM3, SLC15A3, and CNP contribute to lysosome acidification.

47 NP regression models and the phasing SNP and CNP haplotypes (chi2df2=3190,p=7.23x10-08).

48 ported SNPs in SLC2A9 as assessed by SNP and CNP regression models and the phasing SNP and CNP haplot

49 y was downregulated in Npr2(+/-) valves, and CNP triggered synthesis of cGMP and activation of cGK1 (

50 dius CNPs with a cavity near the orifice and CNPs with an open path in the middle, in which the volum

51 Several primate lentiviruses are CNP-sensitive, and CNP sensitivity/resistance is determi

52 PEGylated CNPs is compared to those of bare CNPs, and the differences are outlined.

53 A negatively charged uncoated, "bare" CNP with high luminescence loses its PL when positively

54 Although biallelic CNPs show a strong correlation of copy number with flank

55 nique regions (p = 0.015) and that biallelic CNPs show greater stratification when compared to freque

56 (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more specific (100% versus 80%; P < 0.0001) and

57 V1 as a novel signaling cascade recruited by CNP in mouse DRG neurons that can lead to enhanced nocic

58 ctive oxygen species (ROS) were generated by CNPs.

59 e assessed the global alterations induced by CNPs in A549 lung cells using biospectroscopy techniques

60 rst-order, microbial implicit approach (CASA-CNP), and two recently developed microbially explicit mo

61 n cultured porcine valve interstitial cells, CNP inhibited pathological differentiation via the guany

62 This is the first study to characterize CNPs in ARIC and the first genome-wide analysis of CNPs

63 Similarly, negatively charged CNPs with hydroxyl and carboxylic functionalities did no

64 arable to those caused by positively charged CNPs.

65 cal needs are high-resolution maps of common CNPs and techniques that accurately determine the alleli

66 ween pairs of individuals were due to common CNPs with an allele frequency >5%, and more than 99% der

67 Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more

68 This microarray contained CNPs in segmental duplication-rich regions and insertion

69 is study is to determine whether a deficient CNP signaling axis in mice causes accelerated progressio

70 to examine the valvular effects of deficient CNP/NPR2 signaling in vivo, in the context of both moder

71 The high quantum yield of derived CNPs made them suitable for patterning and staining (flu

72 l of biospectroscopy techniques to determine CNP-induced alterations in target mammalian cells at ppb

73 Most common, diallelic CNPs were in strong linkage disequilibrium with SNPs, an

74 we have studied the effect of five different CNPs on a model relevant aquatic microorganism.

75 the feasibility of imputing newly discovered CNPs and SNPs.

76 Herein, DOX-encapsulated CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhi

77 iomarkers of cell alteration induced by each CNP type were identified.

78 Herein, DOX-encapsulated CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-

79 CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhibited similar physicochemical prop

80 pe caused by genetic deletion of endothelial CNP, but not NPR-C, can be rescued by pharmacological ad

81 Our data establish CNP/NPR2 signaling as a novel regulator of aortic valve

82 eurial arterioles express CNP, and exogenous CNP causes a concentration-dependent vascular relaxation

83 Epineurial arterioles express CNP, and exogenous CNP causes a concentration-dependent

84 ion, 2) GC-B phosphorylation is required for CNP-dependent activation by the A488P mutation, 3) the R

85 fine a central (patho)physiological role for CNP in angiogenesis and vascular remodeling in response

86 n, we sought to delineate a central role for CNP in angiogenesis and vascular remodeling in response

87 l cortical signals and their application for CNPs, including intention, motor imagery, decision makin

88 ical cohorts, the use of SNPs as markers for CNPs and statistical challenges in testing CNVs for asso

89 The results reveal that flame-formed CNPs behave like an indirect band gap material, and that

90 ogen peroxide and demonstrate an enzyme-free CNP-based biosensor capable of ultra-low (limit of quant

91 t, the R655C mutation converted GC-B-7A from CNP-unresponsive to CNP-responsive.

92 Furthermore, CNP injection into mouse hindpaw led to the development

93 f-function allele of a myelin-specific gene (CNP rs2070106-AA) associated with catatonia in 2 indepen

94 l study of CNVs, the challenge of genotyping CNPs in clinical cohorts, the use of SNPs as markers for

95 Here, multifunctional glycol CNPs designed to overcome multiple obstacles to their us

96 Neurofibroma number increased in homozygous CNP-hEGFR mice versus heterozygous littermates, and neur

97 amino acid difference in murine versus human CNP determines Gag binding and antiviral activity.

98 In CNP-Cre;Cdk5(fl/fl) conditional knock-out mouse (Cdk5 cK

99 functional remyelination were accelerated in CNP-hEGFR mice compared with wild-type mice.

100 Sox17 overexpression in CNP-Sox17 mice sequentially promoted postnatal oligodend

101 supports the origin of photoluminescence in CNP as a surface phenomenon correlated a function of cha

102 improved by the solTNF inhibitor XPro1595 in CNP-cre:TNFR2(fl/fl) mice, indicating that for tmTNF to

103 Mice encode an inactive CNP variant and a single amino acid difference in murine

104 These include CNPs that are likely to be under positive selection, mos

105 We inferred a total of 2658 independent CNPs, 56% of which overlap genes.

106 study, we generated a transgenic mouse line (CNP/dnIRF-1) that overexpresses the dominant-negative fo

107 ntify a biological characteristic of macular CNP in malaria that had previously only been described s

108 igodendrocytes that expressed myelin markers CNP and Tmem10/Opalin.

109 Sox10), and mature oligodendrocyte markers (CNP, MBP) were quantified.

110 operties of MF-CNPs (smooth surfaces) and MF-CNP aggregations were characterized (RLCA aggregation of

111 xtraction and visualization of individual MF-CNPs that are mainly composed of high melting triacylgly

112 on of milk fat-crystalline nanoplatelets (MF-CNPs).

113 er-Porod models, structural properties of MF-CNPs (smooth surfaces) and MF-CNP aggregations were char

114 Elucidation of MF-CNPs provides a new dimension of analysis for describing

115 s were characterized (RLCA aggregation of MF-CNPs to form larger structures that present diffused sur

116 y image analysis, the length and width of MF-CNPs were measured (600 nm x 200 nm-900 nm x 300 nm).

117 stalline domain size, (i.e., thickness of MF-CNPs), was determined (27 nm (d001)).

118 and numerical simulations were used to model CNP responses.

119 ing SNP genotypes, the majority of multicopy CNPs do not (40% with r > 0.8).

120 ts of nitrogen-doped carbon nanoparticles (N-CNPs) and nitrogen-doped graphene quantum dots coupled t

121 Cerium oxide nanoparticles (nanoceria; CNPs) have been found to have both pro-oxidant and anti-

122 toluminescence (PL) of carbon nanoparticles (CNP) can be achieved with counterionic macromolecular ca

123 any manufactured carbon-based nanoparticles (CNPs) into our environment, generating a debate into the

124 t, glycol chitosan (GC)-based nanoparticles (CNPs) serve as an effective platform vehicle that can en

125 stem, especially carbon-based nanoparticles (CNPs).

126 ation mechanism of carbogenic nanoparticles (CNPs), otherwise referred to as C-dots, by following the

127 atom-doped fluorescent carbon nanoparticles (CNPs) by a unique combination of sonochemical, microwave

128 nd optical band gap of carbon nanoparticles (CNPs).

129 ic processing of carbonaceous nanoparticles (CNPs) may play an important role in determining their fa

130 Ceria nanoparticles (CNPs) have been demonstrated to neutralize free radical

131 Glycol chitosan nanoparticles (CNPs) are shown to accumulate in tumors, suggesting that

132 Cerium oxide nanoparticles (CNPs) contain several properties such as catalytic activ

133 ect synthesis of cerium oxide nanoparticles (CNPs) in polyethylene glycol (PEG) based solutions with

134 ity of carbon based spherical nanoparticles (CNPs) through defined chemistry and a vigilant choice of

135 dopamine sensors based on carbon nanopipets (CNP) prepared by chemical vapor deposition of carbon int

136 Here, we employ carbon-coated nanopipets (CNPs) for studying permselective electrochemistry in a c

137 In this work, open carbon nanopipettes (CNPs) with radius between 50 and 600 nm were used to con

138 nd, in the culture of embryonic DRG neurons, CNP stimulates branch formation, induces axon outgrowth,

139 knowledge of the roles and mechanisms of NO, CNP and cGKII signaling in cartilage and endochondral bo

140 Comparisons of coding and noncoding CNPs, however, reveal a strong effect of purifying selec

141 (21.6 disc areas) of capillary nonperfusion (CNP) who were followed for 18 months before the availabi

142 For FLAG-NPR-C, neither ANP, BNP, nor CNP increased its internalization in either cell line.

143 First, the C-type NP (CNP) is expressed in a restricted area of the dorsal spi

144 aqueous conditions, and glycol chitosan NPs (CNPs) have been extensively studied for the past few dec

145 sequencing read depth to successfully obtain CNP genotypes for 1495 CNPs from 487 human DNA samples o

146 rescued by pharmacological administration of CNP.

147 t detected at 2h, LH decreases the amount of CNP available to bind to the receptor.

148 Application of CNP potentiated capsaicin- and proton-activated TRPV1 cu

149 The area of CNP increased significantly with higher levels of CVP an

150 best-corrected visual acuity (BCVA), area of CNP, retinal fluorescein transit time (FTT), and an eval

151 ence of rubeosis iridis, and larger areas of CNP that correlate with the degree of CVP elevation.

152 The in vitro angiogenic capacity of CNP was examined in pulmonary microvascular endothelial

153 e of a maximally activating concentration of CNP.

154 Specifically, disruption of CNP leads to endothelial dysfunction, hypertension, athe

155 his review, we summarize the distribution of CNP, its evolutionary dynamics within populations, its f

156 The proangiogenic effect of CNP/NPR-C is dependent on activation of G(i), ERK1/2, an

157 addition, strong complementary expression of CNP was detected in the hindbrain at the entry zones of

158 Mechanistically, expression of CNP-hEGFR increased SCP/neurofibroma-initiating cell sel

159 ertension by demonstrating the importance of CNP/NPR-C signaling in preserving vascular homoeostasis.

160 er, genetic or pharmacological inhibition of CNP and NPR-C, but not NPR-B, reduces the angiogenic pot

161 schemia is associated with reduced levels of CNP and its cognate NPR-C.

162 Some cell types express high levels of CNP and we speculate that CNP evolved to restrict lentiv

163 f rat NPR-A due to the promiscuous nature of CNP in this species.

164 Most patterns of CNP in D. melanogaster suggest that negative selection a

165 mpares favourably with the raw percentage of CNP-pixels and also with manual grading.

166 This quantifies the percentage of CNP-pixels in each of 48 sectors and then characterises

167 for improving sensitivity and selectivity of CNP sensors for ionic analytes.

168 ances, significant biases remain in terms of CNP discovery and genotyping.

169 , and superoxide dismutase (SOD) activity of CNPs synthesized in various concentration of PEG did not

170 n ARIC and the first genome-wide analysis of CNPs and uric acid.

171 In particular, a recent application of CNPs has shown great potential as an efficient theranost

172 es can increase the range of applications of CNPs.

173 g at higher temperatures, the PL behavior of CNPs strongly depends on the conditions used for their s

174 The current challenges of CNPs to overcome in theranostics are also discussed, and

175 c approach for assessing the contribution of CNPs to heritable traits in large population-based studi

176 ent with the theory and the baseline data of CNPs from stretched-stabilized ethylene flames, thus ind

177 discuss the advantages and disadvantages of CNPs-based biosensors that function through various dete

178 The locations and frequencies of CNPs are strongly shaped by purifying selection, with de

179 e demonstrate that exome-based genotyping of CNPs strongly correlates with whole-genome data (median

180 a model, aimed to investigate the impact of CNPs on marine microgel formation, a critical shunt betw

181 s induced by real-world levels of a panel of CNPs.

182 Several preparations of CNPs with varying Ce(3+):Ce(4+) are produced and are ana

183 Among the various shapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high

184 plex provides the tunable oxidation state of CNPs.

185 capacity of the active 3+ oxidation state of CNPs.

186 We selected a subset of CNPs for further characterization in 1876 additional sam

187 Synthesis of CNPs in PEG demonstrated a concentration dependent (of P

188 from solonaceae family for the synthesis of CNPs.

189 New methods demonstrate the ubiquity of CNPs in eukaryotes and their medical importance in human

190 w that the DNP tail has a striking effect on CNP, converting it from a non-agonist to a partial agoni

191 ment simulations of electrostatic effects on CNP voltammograms show permselective ion transport in a

192 is article, the overall research progress on CNPs is reviewed from early works.

193 Here, small and sharp open CNPs were employed to carry out intracellular VIEC with

194 se to 100 pM dopamine was obtained with open CNPs.

195 ure patterns over the Central North Pacific (CNP) imparts a significant signature upon the seasonal-m

196 hift from the oceanic central North Pacific (CNP) to the neritic east Pacific region near the Baja Ca

197 n increase in ambient carbonaceous particle (CNP) levels has been found, potentially leading to signi

198 PEGylated CNPs acted as efficient radical scavengers, and superoxi

199 ability as well as SOD activity of PEGylated CNPs is compared to those of bare CNPs, and the differen

200 ents the fusion of the 22-amino acid peptide CNP together with the 15-amino acid linear C-terminus of

201 C-type natriuretic peptide (CNP) antagonizes FGFR3 downstream signaling by inhibitin

202 tide composed of C-type natriuretic peptide (CNP) fused to the C-terminal tail of Dendroaspis natriur

203 rial arterioles, C-type natriuretic peptide (CNP) has properties consistent with EDHF-like activity.

204 c oxide (NO) and C-type natriuretic peptide (CNP) in the regulation of cartilage development.

205 C-type natriuretic peptide (CNP) is a fundamental endothelial signaling species that

206 roBNP(1-108), or C-type natriuretic peptide (CNP) is not well understood.

207 h Galpha(i), and C-type natriuretic peptide (CNP) treatment induced translocation of protein kinase C

208 c, which encodes C-type natriuretic peptide (CNP), and determined that this mediator is essential for

209 the receptor for C-type natriuretic peptide (CNP), guanylyl cyclase B (GC-B, also known as Npr2 or NP

210 ed of the ligand C-type natriuretic peptide (CNP), its receptor, the guanylyl cyclase natriuretic pep

211 oys an analog of C-type natriuretic peptide (CNP), which antagonizes the mitogen-activated-protein (M

212 e to the agonist C-type natriuretic peptide (CNP).

213 ve properties of C-type natriuretic peptide (CNP).

214 Capillary non-perfusion (CNP) lesions are central to the pathogenesis of major ca

215 '-3'-cyclic nucleotide 3'-phosphodiesterase (CNP) are associated with the schizophrenic symptom catat

216 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) promoter-driven overexpression of human EGFR (hEGFR

217 ',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP), a membrane-associated protein with unknown functio

218 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-enhanced green fluorescent protein transgenic mouse

219 k gap and reach the charge neutrality point (CNP).

220 as well as genotype copy number polymorphic (CNP) loci with high sensitivity and specificity from exo

221 We characterize copy-number polymorphism (CNP) across genomic regions, and we contrast patterns to

222 nd implications of copy number polymorphism (CNP) have only recently become apparent in other organis

223 several of these copy-number polymorphisms (CNPs) are associated with human diseases, including lupu

224 In addition, copy number polymorphisms (CNPs) are present at higher frequencies in the populatio

225 Whether copy number polymorphisms (CNPs) contribute to uric acid levels is unknown.

226 le genomic map of copy-number polymorphisms (CNPs) in Drosophila melanogaster.

227 Segmental copy-number polymorphisms (CNPs) represent a significant component of human genetic

228 notypes for 1,320 copy number polymorphisms (CNPs) that segregate at an allele frequency >1%.

229 regions of common copy number polymorphisms (CNPs), calls genotypes of SNPs, identifies rare CNVs via

230 including common copy-number polymorphisms (CNPs), in disease.

231 des both SNPs and copy number polymorphisms (CNPs).

232 nt physiochemical and biological properties, CNPs have been investigated for multimodal imaging and t

233 The cognitive neural prosthetic (CNP) is a very versatile method for assisting paralyzed

234 expression of the structural myelin protein CNP is associated with catatonic signs in an age-depende

235 Like other antiretroviral proteins, CNP displays interspecies variation in antiviral activit

236 The copy-number quantitation (CNP phenotype) represents the total number of segmental

237 These include 10-200 nm radius CNPs with a cavity near the orifice and CNPs with an ope

238 In streptozotocin-induced diabetic rats, CNP-mediated vascular relaxation in epineurial arteriole

239 of the JCI, Janova et al. show that reduced CNP levels correlate with catatonia and white matter inf

240 depleted the casein-bound phosphate region (CNP).

241 oof of concept that BMN 111, a NEP-resistant CNP analog, might benefit individuals with ACH and hypoc

242 tion affected maximum activity at saturating CNP concentrations.

243 various shapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high product and quantum yield

244 Since CNP may be a regulator of vascular function, a vasopepti

245 NPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhibited similar physicochemical properties, incl

246 are impaired in vivo in endothelium-specific CNP(-/-) and NPR-C(-/-), but not NPR-B(-/-), mice; the d

247 solated from wild-type, endothelium-specific CNP(-/-), global natriuretic peptide receptor (NPR)-B(-/

248 hapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high product and quantum yield with good

249 In addition, the synthesized SU-CNPs were employed for quantitative detection of a widel

250 first time, we have successfully used the SU-CNPs for live cell detection of ZnO nanoparticles.

251 compatibility study demonstrated that the SU-CNPs were not harmful to the cell up to a very high conc

252 In addition, the SU-CNPs were successfully utilized for the qualitative and

253 the first time that luminescence switchable CNPs can be synthesized for efficient intracellular trac

254 Bare and carboxyl-terminated CNPs did present some toxicity at the cellular level whi

255 l chromogenic rapid test--the Carba NP test (CNP)--and the modified Hodge test (MHT).

256 likely to be population differentiated than CNPs in unique regions (p = 0.015) and that biallelic CN

257 ess high levels of CNP and we speculate that CNP evolved to restrict lentivirus replication therein.

258 It was found that CNPs exert marked effects in A549 cells and also contrib

259 We observe that CNPs in segmental duplications are more likely to be pop

260 ase association and our results suggest that CNPs (especially those that cannot be imputed from SNP g

261 The CNP approach relies on scientific understanding of the n

262 The CNP conductance has a two-dimensional character on the o

263 The CNP records the cognitive state of the subject, rather t

264 mune responses between the wild-type and the CNP/dnIRF-1 mice were identified throughout the experime

265 Here we use Cre-recombinase driven by the CNP promoter to generate a mouse line with oligodendrocy

266 e its application through an analysis of the CNP located in gene CCL3L1 in 201 families with asthma.

267 was generated to clarify the pattern of the CNP receptor expression.

268 essure intrusions into the subtropics of the CNP, accompanied by the establishment of persistent, qua

269 ressure anomalies over high latitudes of the CNP.

270 The effect of dopamine adsorption on the CNP detection limit is discussed along with the possibil

271 Only the CNP analog has reached clinical trials.

272 We confirmed that the CNP platform applied to two different types of drugs res

273 The major finding of our study was that the CNP/dnIRF-1 mice, compared with the wild-type mice, were

274 Furthermore, these results suggest that the CNP/NPR-C pathway has potential as a disease-modifying t

275 lted in a shift in peaks associated with the CNP region, possibly caused by SHMP sequestering calcium

276 d two different triplet sequences within the CNP ring to their corresponding residues in BNP.

277 an efficient theranostic system because the CNPs could be utilized for a disease-specific theranosti

278 ycyclic aromatic hydrocarbons comprising the CNPs.

279 zed ethylene flames are used to generate the CNPs reproducibly over the range of 4-23 nm in volume me

280 micals could be simply encapsulated into the CNPs through hydrophobic or charge-charge interactions.

281 structure, nitric acid oxidation leaves the CNPs with a surface charge density lower than that of th

282 verning the variation of the band gap of the CNPs studied.

283 ps, measured both in situ and ex situ on the CNPs prepared in several additional flames, are consiste

284 y lower than that of the SWNTs, and thus the CNPs do not form stable dispersions in aqueous media dur

285 For disease-specific theranostics, CNPs could be simply modified with imaging agents, and t

286 ulated kinases 1 and 2, confirming that this CNP analog inhibits fibroblast-growth-factor-mediated MA

287 in Fgfr3(Y367C/+) mice, treatment with this CNP analog led to a significant recovery of bone growth.

288 d Npr2(+/)(-) fibroblasts was insensitive to CNP treatment, whereas aged Npr2(+/)(-) and Npr2(+/)(-);

289 n converted GC-B-7A from CNP-unresponsive to CNP-responsive.

290 l DNA methylation levels in cells exposed to CNPs at 0.1 mg/L were determined using HPLC-MS and genet

291 cking surface Ce(3+) sites of the most toxic CNP, CNP1, with phosphate treatment reverted toxicity an

292 redox chemistry of the most and least toxic CNPs, CNP1 and CNP2, respectively, were modified by incu

293 ation (e.g., NDE1), myelination (e.g., UGT8, CNP) and oligodendrocyte proliferation (e.g., ENPP2, SEM

294 he cognate receptor that primarily underlies CNP-dependent vasoprotective functions and developed sma

295 hical model in which we infer the underlying CNP phenotype from the (single or replicate) quantitativ

296 the electrochemical response of multi-valent CNPs in presence of hydrogen peroxide and demonstrate an

297 neurofibroma number and size increased when CNP-hEGFR was crossed to Nf1(fl/fl);DhhCre mice.

298 ) variably declined after treatment; whereas CNP concentrations showed no consistent change.

299 However, it is unknown whether CNP signaling regulates aortic valve health in vivo.

300 rate guanylyl cyclase receptor compared with CNP.