ライフサイエンスコーパス: COP

1 COP capillaries (inner diameter of 19-28 mum) were succe

2 COP is characterized by patchy peripheral or peribroncho

3 COP-5 consists of rigid, aromatic porphyrin and carbazol

4 COP-5 shows an unprecedented high selectivity in binding

5 COP-hfacac (2) provides rearranged allylic trichloroacet

6 performed to assess the efficacy of Bet v 1 COP immunotherapy during the 2013 birch pollen season.

7 Bet v 1 COP injections were well tolerated, with a higher freque

8 d medication scores improved in both Bet v 1 COP-treated groups, reaching statistical significance ov

9 Before the season, Bet v 1 COPs (50 and 100 mug in aluminum hydroxide) or placebo (

10 Bet v 1 COPs at 25 or 50 mug were administered on day 1, and 50

11 munotherapy using 2 dose regimens of Bet v 1 COPs versus placebo in subjects with birch pollen-induce

12 Copolymer-1 (COP-1) elicits neuroprotective activities in a wide rang

13 CO Probe 1 (COP-1) is capable of detecting CO both in aqueous buffer

14 ifetimes centered at 2.8 ns (representing (1)COP --> Cc ET).

15 o the conformational distributions in the (1)COP --> Cc ET whereas differences in overall porphyrin c

16 A genome scan was carried out on an F(2)(COP x DA) segregating population (n=224) to detect quant

17 We analyzed 21 COP and 39 TF patients.

18 were lost to follow-up, leaving 39 TF and 21 COP for analyses.

19 g with their 2D covalent organic polymer (2D COP) analogues, as energy materials.

20 o months of preseasonal immunotherapy with 3 COPs derived from Bet v 1 at a 50-mug dose showed promis

21 inating from triplet state were examined ((3)COP --> Cc ET).

22 ic cooling power of 2.8 watts per gram and a COP of 13.

23 he first single-crystal X-ray structure of a COP catalyst is also reported.

24 The assembly of such a COP is a thermodynamically controlled process, which inv

25 I, 2.9-4.6) vs. those treated for accidental COP (17 excess deaths; SMR, 1.3; 95% CI, 1.01-1.6).

26 alpha-COP binds to SMN, linking the COPI vesicular transport p

27 ly Golgi associated, in neuronal cells alpha-COP localizes to lamellipodia and growth cones and moves

28 rane proteins are captured by coatomer alpha-COP and beta'-COP subunits and packaged into COPI-coated

29 nding of KKxx motifs by the homologous alpha-COP domain.

30 ably, heterologous expression of human alpha-COP restored normal neurite length and morphology in SMN

31 ound within alpha-COP itself, mediates alpha-COP homo-oligomerization.

32 We present crystal structures of alpha-COP and beta'-COP bound to a series of naturally occurri

33 between the C-terminal domain (CTD) of alpha-COP and full-length epsilon-COP, two components of the B

34 Reduced levels of alpha-COP restricted development of neuronal processes in NSC-

35 Depletion of alpha-COP resulted in mislocalization of SMN and actin at the

36 dentified single amino acid mutants of alpha-COP that selectively abrogate SMN binding, retain COPI-m

37 y a conserved site on the COPI subunit alpha-COP that binds to flexible, acidic sequences containing

38 Binding experiments show that alpha-COP and beta'-COP have generally the same specificity fo

39 Together, our findings suggest that alpha-COP homo-oligomerization plays a key role in COPI coat s

40 The alpha-COP CTD adopts a U-shaped architecture that complements

41 round a protruding beta-hairpin of the alpha-COP CTD, thus interlocking the two proteins.

42 The alpha-COP protein co-immunoprecipitates with SMN, small nuclea

43 The alpha-COP(CTD) x epsilon-COP complex forms heterodimers in sol

44 The alpha-COP(CTD) x epsilon-COP heterodimer forms a rod-shaped st

45 One such sequence, found within alpha-COP itself, mediates alpha-COP homo-oligomerization.

46 Strikingly, the alphabeta'-COP core of coatomer crystallizes as a triskelion in whi

47 pathway negatively regulated by the DET1 and COP proteins.

48 ealed for producing tailor-made graphene and COP materials for efficient energy conversion and storag

49 Coat protein (COP) I and COP II complexes are involved in the transport of protei

50 amics that are dependent on microtubules and COP-II but not on COP-I vesicle machinery.

51 cally, BTZ and CFZ absorption in both PS and COP were all in the range of approximately 100-300 nm, w

52 an expansion of the number of SNARE, Rab and COP proteins.

53 oured both astaxanthin degradation (83%) and COPs formation (886.6 +/- 97.9 mug/g of lipids after 90

54 In both (ACI x COP)F(2) and (COP x ACI)F(2) populations, we find strong evidence for

55 triskelion in which three copies of a beta'-COP beta-propeller domain converge through their axial e

56 ubiquitin from Snc1, or deletion of a beta'-COP subunit propeller domain that binds K63-linked polyu

57 nt crystal structures of alpha-COP and beta'-COP bound to a series of naturally occurring retrieval m

58 ng experiments show that alpha-COP and beta'-COP have generally the same specificity for KKxx and KxK

59 are captured by coatomer alpha-COP and beta'-COP subunits and packaged into COPI-coated vesicles for

60 ditionally reveals cargo bound beneath beta'-COP.

61 Flexibility between beta'-COP WD-repeat domains and the location of cargo binding

62 to the N-terminal WD-repeat domain of beta'-COP identifies electrostatic contacts between the motif

63 tif backbone with basic side chains of beta'-COP.

64 ecificity for KKxx and KxKxx, but only beta'-COP recognizes the RKxx signal.

65 Moreover, replacement of the beta'-COP propeller domain with unrelated ubiquitin-binding do

66 lementary patches at the center of the beta'-COP propeller.

67 beta-COP and several Galpha subunits (Galpha(i1-3), Galpha(s)

68 Beta-COP depletion did not affect CFTR synthesis but impaired

69 ly interacts with at least zeta-COP and beta-COP of the COPI coatomer complex.

70 om both cerebellum and COS-7 cells, and beta-COP protein interacted directly with immobilized KA2 pep

71 -COP at a site common to the gamma- and beta-COP subunits.

72 ps with cellular Golgi proteins such as beta-COP and GS-28, G(C) expressed in the absence of G(N) loc

73 : an N-terminal dibasic site that binds beta-COP to hold channels in ER and a C-terminal "release" si

74 intermediate compartment that contains beta-COP, which is best known as a component of the COPI coat

75 d CFTR in epithelial cells, we depleted beta-COP from the human colonic epithelial cell HT-29Cl.19A u

76 ition, we demonstrate a requirement for beta-COP as a cellular cofactor for Nef that was necessary fo

77 ere observed and buds were labelled for beta-COP.

78 es that contained Rab2, PKCiota/lambda, beta-COP, and p53/p58.

79 and caused dispersion of Golgi markers beta-COP and GM130, whereas ER structure appeared intact.

80 and shows mutually exclusive binding of beta-COP and 14-3-3beta on adjacent N-terminal sites.

81 ssary for the downstream recruitment of beta-COP and release of Rab2-mediated retrograde-directed ves

82 compromised, as shown by the release of beta-COP into the cytosol.

83 tional consequence as cells depleted of beta-COP showed decreased cAMP-activated chloride currents.

84 branes contained a negligible amount of beta-COP that was reflected by the drastic reduction in Rab2-

85 anes were evaluated for the presence of beta-COP.

86 n with the Golgi membrane markers p115, beta-COP, and the trans-Golgi network marker, syntaxin 6.

87 tream recruitment of beta-coat protein (beta-COP) to VTCs, the Rab2-PP2-treated membranes were evalua

88 tor, ArfGAP2/3, and the adaptor protein beta-COP-enable GIV to coordinately regulate Arf1 signaling.

89 omerase (PDI) and the COPI coat protein beta-COP.

90 ase alpha-subunit and the coat protein, beta-COP, a component of the COP-I complex.

91 Because Rab2, beta-COP, and p53/p58 are marker proteins for pre-Golgi inter

92 Moreover, some beta-COP colocalizes with intracellular caveolin-1, which was

93 din A, except that the coatomer subunit beta-COP remained on Golgi-derived membrane tubules.

94 orylation-dependent fashion to suppress beta-COP binding and allow forward transport.

95 ectron microscopy, GIV colocalizes with beta-COP and Galpha(i3) on vesicles found in close proximity

96 he alpha-subunit does not interact with beta-COP and traffics to the plasma membrane.

97 nthesized alpha-subunit associates with beta-COP immediately after its synthesis but that this intera

98 The interaction with beta-COP was reduced by mutating a dibasic motif at Lys(54) i

99 sicles was based on colocalization with beta-COP, a marker for these vesicles.

100 a,K-ATPase alpha-subunit interacts with beta-COP, is retained in the endoplasmic reticulum, and is ta

101 A resolution crystal structure of betadelta-COP.

102 second Arf1-GTP molecule binds to betadelta-COP at a site common to the gamma- and beta-COP subunits

103 ctor 1 (Arf1):GTP-binding betagammadeltazeta-COP F-subcomplex, which is related to the adaptor protei

104 ellent enantiomeric purities (87-98% ee) by [COP-OAc](2)-catalyzed cyclization of phenolic (E)-allyli

105 vel 3-D rectangular prismatic molecular cage COP-5 in one step from a readily accessible porphyrin-ba

106 ast to previously reported Pd(II) catalysts, COP-OAc (4) promotes the asymmetric cyclization of (Z)-a

107 matographic behavior of the AEX latex-coated COP capillaries are greatly dependent on the degree of s

108 transport vesicles coated with coat complex (COP) II deliver secretory cargo to vesicular tubular clu

109 ER export and interacted with coat complex (COP)II, while an RxR motif also played an important role

110 sicle coats similar to coat protein complex (COP) I, COPII, and clathrin.

111 Quantification of coat protein complex (COP) II assembly revealed a dramatic up-regulation at ex

112 hat TRAPPIII binds the coat protein complex (COP) II coat subunit Sec23.

113 ates catalyzed by the palladium(II) complex [COP-OAc](2) is a broadly useful method for the asymmetri

114 Five WF.COP congenic lines containing COP RN02 segments were compared.

115 Copenhagen (COP) and DA inbred rat strains show a wide difference in

116 the genetically related ACI and Copenhagen (COP) rat strains.

117 rait in crosses to the resistant Copenhagen (COP) strain.

118 etically related, but resistant, Copenhagen (COP) rat strain.

119 s previously been shown that the Copenhagen (COP) rat contains several genetic loci that contribute t

120 rs decreased susceptibility when Copenhagen (COP)-resistant alleles are introgressed into a Wistar Fu

121 l system involving free-base coproporphyrin (COP) complexed with horse heart cytochrome c (Cc).

122 bstrate receptor of E3 ubiquitin ligase CUL4(COP) (1-) (SPA) (s) , interacts with the diverse VP moti

123 system can operate up to 84% of Carnot cycle COP at a temperature span of 41 K, which cannot be obtai

124 xpression of others (such as dergic53, dbeta'COP, and drab6).

125 ents, we show that COPI subunit delta (delta-COP) affects the biology of APP, including its subcellul

126 ode of binding and show that mammalian delta-COP binds related tryptophan-based motifs such as that f

127 ndings demonstrate the crucial role of delta-COP in APP metabolism and, consequently, the generation

128 By scanning the length of delta-COP via functional complementation in yeast, we dissect

129 monstrating that, by targeting subunit delta-COP function, the moderation of the COPI-dependent traff

130 We conclude that delta-COP subunits bind Wxn(1-6)[WF] motifs within unstructure

131 n yeast, we dissect the domains of the delta-COP subunit.

132 f at its extreme C terminus to bind to delta-COP at the same site in the same way.

133 rminal mu-homology domain of the yeast delta-COP subunit in complex with the WxW motif from its bindi

134 previously described chloride-bridged dimer COP-Cl (1).

135 ude attainment of complete response after DR-COP with highly active antiretroviral therapy.

136 mab plus pegylated liposomal doxorubicin (DR-COP) in an attempt to provide a more practical approach

137 ors, and the cargo-binding alphabeta'epsilon-COP B-subcomplex.

138 Clathrin, Sec13-Sec31, and alphabeta'epsilon-COP.

139 s arose in mutants deficient in both epsilon-COP and either Cog1 or Cog2.

140 ly 10 min later by a COPI component (epsilon-COP) and a trans-Golgi network (TGN) marker (GRIP70).

141 n (CTD) of alpha-COP and full-length epsilon-COP, two components of the B-subcomplex, at a 2.9 A reso

142 y small interfering RNA depletion of epsilon-COP in wild-type cells under conditions in which COG-ins

143 ure that complements the TPR fold of epsilon-COP.

144 epleted of the temperature-sensitive epsilon-COP subunit.

145 We show that epsilon-COP depletion for 12 h caused a primary block to virus i

146 SEC28 encodes the epsilon-COP subunit of COPI (coat protein complex I) coatomer pr

147 The epsilon-COP TPRs form a circular bracelet that wraps around a pr

148 rms a rod-shaped structure, in which epsilon-COP adopts a tetratricopeptide repeat (TPR) fold that de

149 The alpha-COP(CTD) x epsilon-COP complex forms heterodimers in solution, and we demon

150 The alpha-COP(CTD) x epsilon-COP heterodimer forms a rod-shaped structure, in which e

151 ting of a discrete lifetime at 15.0 ns (free COP) and a Gaussian distribution of lifetimes centered a

152 ein, an Arf GTPase, and a coat protein (e.g. COPs, APs, or GGAs) are minimal components required for

153 model is proposed in which ERManI and gamma-COP contribute to a Golgi-based quality control module t

154 by the requirement of both ERManI and gamma-COP to support efficient intracellular clearance of the

155 l interaction between NHK, ERManI, and gamma-COP was identified by co-IP and Western blotting.

156 direct interaction between ERManI and gamma-COP, the gamma subunit of coat protein complex I (COPI)

157 RNA interference-mediated knockdown of gamma-COP enhanced the association between ERManI and NHK, whi

158 site-directed mutagenesis of suspected gamma-COP-binding motifs in the cytoplasmic tail of ERManI was

159 the structure of Arf1 bound to the gammazeta-COP subcomplex of coatomer.

160 ting of the back ET reaction (reduced Cc --> COP(+)).

161 o older persons with no recent fall history (COP Displacement, Short Term Diffusion Coefficient, and

162 However, COP and pelvic movement were significantly later in the

163 of Sac1 is required for coatomer complex-I (COP-I)-binding and continuous retrieval to the ER.

164 cting ENaC to the Golgi via coat complex II (COP II) during biogenesis.

165 Importantly, COP-1 immunization reduced astro- and microgliosis while

166 reased 10.6-fold in ACI rats and 4.5-fold in COP rats.

167 that acetate is a competent leaving group in COP-catalyzed enantioselective S(N)2' substitution react

168 uent carbonization of the metal-incorporated COPs led to the formation of COP-derived graphene analog

169 d colour values, TBARs, total and individual COPs, and the rancidity became pronounced.

170 tients (14%) had < a 20% response to initial COP (cyclophosphamide, vincristine, and prednisone) ther

171 the group treated initially for intentional COP (58 excess deaths; SMR, 3.7; 95% CI, 2.9-4.6) vs. th

172 Interestingly, COP-5 serves as an excellent receptor for fullerenes.

173 nd decrease in 5-ch-3beta-ol-7-one and lower COPs were observed in low-fat goshtaba containing 1.5% X

174 uction in cholesterol and formation of lower COPs were observed in low-fat goshtaba formulated with 1

175 7-Ketocholesterol was the main COP in most cases during the whole heating treatment.

176 (COF) or an amorphous, microporous material (COP).

177 those taken from young adults (e.g., maximal COP velocity was 2.7x greater in fallers than young adul

178 ines were generated by transferring the Mcs1 COP allele onto a Wistar Furth (WF) genetic background.

179 on of these independent loci within the Mcs1 COP allele provide a model of the genetic complexity of

180 tly been elucidated, but the effects of most COPs and POPs on inflammasome assembly have not been inv

181 Long nano-COP reads reveal that, in human and Drosophila cells, sp

182 lysis of co-transcriptional processing (nano-COP), in which nascent RNAs are directly sequenced throu

183 Thus, nano-COP unveils the organizational complexity of RNA process

184 solvent bonding of PS or thermal bonding of COP, to alleviate the adverse effects of heterogeneous a

185 d IL-4-expressing lymphocytes into brains of COP-1-immunized animals was observed.

186 f Sec24D, the cargo recognition component of COP II that we previously demonstrated to interact with

187 The temporal events of COP and pelvic movement were not significantly different

188 Another interesting feature of COP capillaries lies in their flexibility.

189 performed using RNA extracted from femurs of COP, DA, F344 and LEW rats.

190 The formation of COP I/II complexes at membrane surfaces is an early step

191 al-incorporated COPs led to the formation of COP-derived graphene analogues, which acted as efficient

192 Here, we discuss our model of COP- and POP-mediated inflammasome regulation.

193 s were recorded and analyzed as the onset of COP and pelvic movement, the COP displacement, and cocon

194 Seventy-one percent of COP patients were off PPIs six months following TF.

195 The most common HRCT presentation of COP was ground-glass opacity (GGO) in 83.9% of cases, fo

196 The main presentations of COP on HRCT include bilateral GGOs and consolidations in

197 shed as a routine method for the analysis of COPs in foods.

198 ation is a necessary step in the analysis of COPs in order to eliminate interferences and increase se

199 of astaxanthin and the elevated formation of COPs during sun drying and storage indicate the necessit

200 thods for the extraction and purification of COPs.

201 The main source of COPs is through diet, and particularly from the consumpt

202 endent on microtubules and COP-II but not on COP-I vesicle machinery.

203 larvae with IAP (inhibitor of apoptosis) or COP (COPI coatomer, beta subunit) dsRNA silenced their t

204 Cobalt oxazoline palladacycles (COP) containing acetylacetonate and hexafluoroacetylacet

205 Cobalt oxazoline palladacyclic (COP) complex 4 containing acetate as a bridging ligand i

206 During the Third Conference of Parties (COP-3) in November 2019, elimination of the use of denta

207 comes 6-month post TF in crossover patients (COP), as compared to 6-month of HD PPI therapy, and 12-m

208 isting of 3 contiguous overlapping peptides (COPs) derived from Bet v 1, the major birch pollen aller

209 ower with a high coefficient of performance (COP) and the ability to be applied directly to surfaces.

210 bodies with CONSTITUTIVELY PHOTOMORPHOGENIC (COP) 1, a RING motif-containing E3 ligase.

211 roup of evolutionarily conserved pleiotropic COP/DET/FUS proteins was initially defined by their abil

212 the working hypothesis that the pleiotropic COP/DET/FUS group of proteins defined a protein ubiquiti

213 atterns of cryptogenic organizing pneumonia (COP) in X-rays have been reported for more than 20 years

214 (RB-ILD), cryptogenic organizing pneumonia (COP), acute interstitial pneumonia (AIP), and lymphoid i

215 sive natural seep field near Coal Oil Point (COP), California.

216 viving acute carbon monoxide (CO) poisoning (COP) may have increased risk for long-term mortality.

217 inue to promote community-oriented policing (COP) and its emphasis on positive, nonenforcement contac

218 ape-persistent covalent organic polyhedrons (COPs) with ethynylene linkers are usually prepared throu

219 pe-persistent, covalent organic polyhedrons (COPs).

220 We describe novel cycloolefin polymer (COP)-based open tubular capillary ion exchange columns.

221 ted surface-sulfonated cyclo-olefin polymer (COP) capillary column with an inner diameter (i.d.) of 2

222 s polystyrene (PS) and cyclo-olefin polymer (COP) have become common materials for fabrication of mic

223 posable and single-use cyclo-olefin polymer (COP) microfluidic chip interfaced with a quantitative re

224 ctrodes deposited onto Cyclo Olefin Polymer (COP) substrates was fabricated for the detection of Camp

225 als (polystyrene (PS), cyclo-olefin polymer (COP), and PDMS).

226 A class of 2D covalent organic polymers (COPs) incorporating a metal (such as Fe, Co, Mn) with pr

227 (COF) and two new covalent organic polymers (COPs) made with fluoranthene-containing monomers and hex

228 Center of pressure (COP) was measured during 4 minutes of quiet stance with

229 and displacements of the center of pressure (COP) were quantified within time intervals typical for A

230 ce plate to identify the center of pressure (COP), and its anteroposterior (AP) and mediolateral (ML)

231 The center of pressure (COP), pelvic movements, and muscle activities were recor

232 tion (SVS) on body sway (center-of-pressure, COP) during standing and walking at different speeds and

233 Cholesterol oxidation products (COPs) and peroxides were formed during the heating treat

234 ecent years, cholesterol oxidation products (COPs) have drawn scientific interest, particularly due t

235 formation of cholesterol oxidation products (COPs) in low-fat meat product (goshtaba) of Jammu and Ka

236 rmination of cholesterol oxidation products (COPs) in milk powder based foods is reported.

237 hrimp, while cholesterol oxidation products (COPs) showed a dramatic increase (8.6-fold), reaching a

238 (TBARs) and cholesterol oxidation products (COPs), and the rancidity was more pronounced.

239 describe the clash opportunity progressive (COP) computational method for designing a mutant aaRS to

240 Coat protein (COP) I and COP II complexes are involved in the transpor

241 p115 tethers coat protein (COP)I vesicles to Golgi membranes.

242 SCAP incorporation into common coat protein (COP)II-coated vesicles.

243 cided with a marked slowing of coat protein (COP)II-mediated protein export.

244 We have identified a novel protein, COP (CARD only protein), which has a high degree of sequ

245 These CARD-only proteins (COPs) and PYD-only proteins (POPs) function as endogenou

246 s (POPs) and the related CARD-only proteins (COPs) in regulating inflammasome responses and their imp

247 4.3+/-11 years; 55% male) with biopsy-proven COP in a tertiary lung center between 2009 and 2012 were

248 decoy proteins encoding only a CARD or PYD, COPs and POPs, respectively, are assumed to inhibit infl

249 cyclobutadiene)cobalt]dipalladium, (R(p),S)-[COP-OAc](2), or its enantiomer.

250 Similarly, COPs are suggested to bind to the CARD of caspase-1 to p

251 idence of bacteremia and the admitting SMART-COP and PORT scores were similar in patients with and wi

252 isease at admission was assessed using SMART-COP and Pneumonia Outcomes Research Team (PORT) scoring

253 Variance of elderly subjects' COP measures from the young adult cohort were weighted t

254 Latex attachment on sulfonated COP surfaces are much stronger; several types show suffi

255 SVS-COP coupling decreased from standing to walking and furt

256 SVS-COP coupling was determined by correlation analysis in f

257 Furthermore, SVS-COP coupling depended on the gait-cycle-phase with peaks

258 und to give significantly higher values than COP hearts for: (1) maximal developed tension (38.3 % gr

259 We conclude that COP-1 may warrant therapeutic consideration for HIV-1-as

260 he surface water refutes the hypothesis that COP seep methane appreciably influences carbon dioxide d

261 a metabolic encephalopathy, we reasoned that COP-1 could be developed as an adjunctive therapy for di

262 10 generation was treated with DMBA, and the COP homozygous rats developed 1.5 +/- 0.3 carcinomas/rat

263 for which each locus was homozygous for the COP allele, tumor development was reduced by approximate

264 In the COP, TF further improved control of regurgitation and of

265 as the onset of COP and pelvic movement, the COP displacement, and cocontraction and reciprocal muscl

266 present and constitute resting states of the COP catalyst (however, monomeric palladium(II) complexes

267 catalyzed by palladium(II) complexes of the COP family is a powerful method for the preparation of e

268 realized with palladacyclic complexes of the COP family.

269 AM83H and SEC16A, a protein component of the COP II complex at endoplasmic reticulum exit sites.

270 The outcomes of the COP-3 meeting included a call for information on the ava

271 e coat protein, beta-COP, a component of the COP-I complex.

272 t targeting of REMORIN is independent of the COP-II-dependent secretory pathway and mediated by PI4P

273 Golgi in a process that is dependent on the COP-II complex and ARF GTPases.

274 of the congenic lines minimally retained the COP allele at D2Mit29 on the centromeric end of chromoso

275 Seeing that the COP seep field is one of the biggest natural seeps, a lo

276 of these sites is functionally linked to the COP I-dependent C-terminal dilysine ER retrieval pathway

277 With the COP design algorithm we then designed a mutant tyrosyl t

278 CNS initiated a step was identical with the COP then pelvic movement.

279 The COPs determined were 7-beta-OH-ch, 5-ch-3beta-ol-7-one a

280 e thermodynamic stabilities of some of these COP structures.

281 To illustrate this COP procedure, we apply it to the design of mutant Metha

282 ntrol the oligomeric state of p24 and, thus, COP vesicle formation.

283 Therefore, we develop an automated web tool-COP (COrrelations by Positional artifacts) to detect the

284 e range 10-36% in fresh samples with a total COPs amount from 212 to 645ngg(-1) and 6-14% for an oxid

285 Maximum total COPs concentrations were achieved at 20 min in neat chol

286 e Mcs1 congenic line that carried one or two COP alleles of the Mcs1 region had a significantly reduc

287 After canning two COPs (7-beta-OH-ch, 5-ch-3beta-ol-7-one) were produced i

288 rnating cycles (total of six cycles) of VAMP/COP chemotherapy followed by response-based, involved-fi

289 -adapted combined-modality therapy with VAMP/COP and response-based, involved-field radiation therapy

290 A WF.COP-D2Mit29/D2Rat201 homozygous congenic strain derived

291 Five WF.COP congenic lines containing COP RN02 segments were com

292 still able to reach the plasma membrane when COP II-directed transport was disrupted by two different

293 by two different mutant forms of Sar1, when COP I-mediated vesicular traffic from the endoplasmic re

294 xit from the ER through its association with COP II.

295 on mechanism analogous to that observed with COP catalysts.

296 ted tomography (HRCT) scans in patients with COP.

297 In both (ACI x COP)F(2) and (COP x ACI)F(2) populations, we find strong

298 locus, Emca2, on chromosome 18 in the (ACI x COP)F(2) population.

299 (P < 0.001) compared with rats carrying zero COP alleles at this locus.

300 Fn specifically interacts with at least zeta-COP and beta-COP of the COPI coatomer complex.